


Concerns have been raised regarding the potential for endocrine disrupting compounds (EDCs) to alter brain development and behavior. Developmental exposure to bisphenol A (BPA), a ubiquitous EDC, has been linked to altered sociosexual and mood-related behaviors in various animal models and children but effects are inconsistent across laboratories and animal models creating confusion about potential risk in humans. Exposure to endocrine active diets, such as soy, which is rich in phytoestrogens, may contribute to this variability. Here, we tested the individual and combined effects of low dose oral BPA and soy diet or the individual isoflavone genistein (GEN; administered as the aglycone genistin (GIN)) on rat sociosexual behaviors with the hypothesis that soy would obfuscate any BPA-related effects. Social and activity levels were unchanged by developmental exposure to BPA but soy diet had sex specific effects including suppressed novelty preference, and open field exploration in females. The data presented here reinforce that environmental factors, including anthropogenic chemical exposure and hormone active diets, can shape complex behaviors and even reverse expected sex differences.













Live birth rates per initiated treatment cycle were measured.













Does BPA disrupt autophagy in the liver?



the BPA pill 

Bisphenol A, commonly known as BPA, is the great unknown threat to western civilization. More dangerous than demographic shifts, Islam, or even the dreaded THOT, it is set to become the most important political issue of our age. At over 6 billion pounds produced per year it is most ubiquitous plasticizer used on earth. It’s xenoestrogens find their way into your body from the of plastic products you use every day. Bisphenol A is in everything, from your plastic bottle of glistening filtered spring water, to the catheter you’ll use once the toxins from BPA turn cells in your prostate cancerous. Did someone hand you a receipt today? Hopefully you had not recently sterilized your hands with that little bottle of congealed rubbing alcohol you have in the car. Ten thousand times more BPA just leeched into your bloodstream because you used hand sanitizer before touching that thermal paper receipt. If that wasn’t already enough, just remember that it’s in your kid’s milk bottle, your toothbrush, your dental implants and fillings, and your Tupperware lunch container that you microwaved earlier. Bisphenol A is It is the cause of your depression, your low T, your man tits. BPA will be the downfall of civilization that no one sees coming.

No BPA in EU Receipts by 2020

from an article published on the European Chemicals Agency site:

In December 2016, the European Commission decided to restrict BPA in thermal paper in the EU. This ban will take effect in 2020, giving manufacturers, importers and users of thermal paper the time to phase it out and find an alternative.

As a result of the restriction, paper manufacturers will need to replace BPA with other dye developers. One potential replacement that is being considered by industry is the chemical Bisphenol S (BPS). However, concerns have been expressed that it may cause similar health problems to BPA. To make sure that one hazardous chemical is not being replaced by another, BPS is currently under substance evaluation and the European Commission has also asked ECHA to further investigate the use of BPS as a substitute for BPA in thermal paper.