Polygonum Cuspidatum Extract Resveratrol Extract Japanese Knotweed Extract

Polygonum Cuspidatum Extract Resveratrol | Japanese Knotweed Extract

What is Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract?

TIZAN Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract is an extract of the roots of Polygonum cuspidatum. It is a type of natural phenol, and a phytoalexin produced naturally by several plants in response to injury or when the plant is under attack by pathogens such as bacteria or fungi. Food sources of resveratrol include the skin of grapes, blueberries, raspberries, mulberries, and senna. It has amazing anti-aging properties, and has others benefits such as cardiovascular effects, anti-cancer, estrogen regulating effects are mentioned here.

Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract Benefits


The study by Harvard Medical School researchers shows that resveratrol stimulates production of SIRT1, a serum that blocks diseases by speeding up the cell’s energy production centers known as mitochondria. It affects the activity of enzymes called sirtuins. Sirtuins control several biological pathways and are known to be involved in the aging process. Resveratrol is only one of many natural and synthetic sirtuin-activating compounds now known. Researchers found that resveratrol can extend the lifespans of yeast, worms, flies and fish.


It is famous for its Cardioprotective effects. It could afford cardioprotection by affecting the expression of nitric oxide synthase.


It can help you beat cancer – from brain tumours to breast, colon, prostate cancers and many more. It induced human promyelocytic leukemia cell differentiation, inhibited enzymes that promote tumor growth, and exerted antitumor effects in neuroblastomas.

Weight Loss

It helps you to lose weight is through reducing the amounts of estrogen that your body produces. Estrogen increases body fat and decreases muscle mass, so reducing the amounts of estrogen produced by your body will help you lose weight and build muscle.

Helps Protect the Brain and Cognitive/Mental Health

It is particularly unique as its antioxidants can cross the blood-brain barrier to protect the brain and the nervous system, unlike other antioxidants. Recent studies show that resveratrol noticeably increased blood flow to the brain, suggesting a considerable benefit to healthy brain function and neuroprotective effects. This means consuming more can increase protection against cognitive/mental problems, including Alzheimer’s, dementia and others.

What is Polygonum cuspidatum?

Polygonum cuspidatum, commonly called Japanese knotweed, is a member of the buckwheat family (Polygonaceae). It is also known as P. japonicum, Reynoutria japonica, Pleuropteris zuccarinii, and Polygonum zuccarinii, as well as false bamboo. A native of eastern Asia, this species grows in waste areas throughout the northeastern United States and into southern Canada. Polygonum cuspidatum extract appear to have antipyretic and analgesic activities. It appeared to confer protection of the gastric membrane against stress ulcers, slight inhibition of gastric secretion, and no effect on blood pressure.

What the benefits of Polygonum cuspidatum root?

Roots of Polygonum cuspidatum contain compounds called stilbenes. One stilbene called resveratrol has several physiological activities. It exhibits cancer chemopreventive activity by acting as an antioxidant, antimutagen, and anti-inflammatory agent. It also induces human promyelocytic leukemia cell differentiation and inhibits the development of preneoplastic lesions. It inhibits protein-tyrosine kinase, which catalyzes the phosphorylation of tyrosine. This kinase is involved in signal transduction in the cytoplasm of a cell involved in the regulation of mitogenesis. The inhibition of protein-tyrosine kinase by resveratrol is possibly antimutagenic by deterring the kinaseõs function. It inhibits lipoxygenase products, which are enzymes found in leukocytes, the heart, brain, lung, and spleen. Resveratrol, and its glucoside precursor, piceid, inhibit the deposition of triglycerides and cholesterol in the liver. Resveratrol, piceid, and another stilbene compound reduced the elevation of aspartate transaminase and alanine transaminase by inhibiting lipid peroxidation in the livers. Analysis of these two enzymes in blood serum gives good diagnostic information for heart and liver damage. These same three compounds have shown potential as an antithrombotic, thus preventing the formation of blood clots within blood vessels.

Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract Specification

Resveratrol (HPLC)98%50%
Emodin (HPLC)0.1%2%
AppearanceWhite PowderBrown Fine Powder
Particle Size100% Pass 80 Mesh
Heavy Metals≤10ppm
Total Plate Count≤1000cfu/g
Yeast and Mold≤100cfu/g

The Best Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract Supplier TIZAN


Why Choose TIZAN Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract?

Tizan specialize in Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

Where to buy Polygonum Cuspidatum Extract Resveratrol Extract | Japanese Knotweed Extract?


Shelf Life

2 Years



  • 1Kg/Bag, aluminum foil bag vacuum packing.

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