Onglyza (Saxagliptin Hydrochloride)

Onglyza (℞)
2.5mg Tablet


Onglyza (℞)
5mg Tablet



Saxagliptin Hydrochloride Information

METFORMIN; SAXAGLIPTIN (met FOR min; SAX a glip tin) is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.


They need to know if you have any of these conditions: -anemia -become easily dehydrated -diabetic ketoacidosis -heart disease -heart failure -history of alcohol abuse problem -if you often drink alcohol -kidney disease -liver disease -low levels of vitamin B12 in the blood -older than 80 years -pancreatitis -polycystic ovary syndrome -previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat -serious infection or injury -thyroid disease -type 1 diabetes -undergoing surgery or certain procedures with injectable contrast agents -an unusual or allergic reaction to metformin, saxagliptin, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding




Do not take this medicine with any of the following medications: -certain contrast medicines given before X-rays, CT scans, MRI, or other procedures -dofetilide -gatifloxacin This medicine may also interact with the following medications: -acetazolamide -amiloride -certain antiviral medicines for HIV infection or hepatitis -calcium channel blockers -certain antibiotics like clarithromycin and telithromycin -certain medicines for fungal infections like ketoconazole and itraconazole -cimetidine -crizotinib -digoxin -diuretics -female hormones, like estrogens or progestins and birth control pills -glycopyrrolate -isoniazid -lamotrigine -memantine -methazolamide -midodrine -morphine -nefazodone -niacin, niacinamide -phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine -phenytoin -procainamide -propantheline -quinidine -quinine -ranitidine -ranolazine -steroid medicines like prednisone or cortisone -stimulant medicines for attention disorders, weight loss, or to stay awake -thyroid medicines -topiramate -trimethoprim -trospium -vancomycin -vandetanib -zonisamide



Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -feeling faint or lightheaded, falls -fever, chills -joint pain -muscle aches or pains -pain in the lower back -signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness -slow or irregular heartbeat -unusual stomach upset or pain -unusually weak or tired -vomiting Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -diarrhea -headache -heartburn -metallic taste in mouth -nausea -runny or stuffy nose -stomach gas, upset




Saxagliptin, Metformin Hydrochloride Oral tablet, extended-release

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