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Morphology of pericytes and the basement membrane shared with endothelial cells was observed with a transmission electron microscope (JEM-1400PLUS; JEOL, Japan).
The team also observed that muscle immobility itself led to a significant decline in the abundance of pericytes in the affected muscle tissues.
Hemangiopericytoma: a vascular tumor featuring zimmermann's pericytes. Ann Surg 1942;116(1):26-33.
SMA-positive pericytes reacted for both endothelial cells and spindle cells in all four reports including the present case which underwent this staining (Table 2).
Others postulate that these cells originated from pericytes, which are essentially progenitors of fat/muscle cells [9,10].
Wakisaka and Nagao first reported the expression of SGLT2 in cultured bovine retinal pericytes [39] highlighting the functional glucose sensor role of SGLT2 in the retinal microvasculature.
Accumulation of sorbitol results in intramural pericytes of retinal capillaries losing their primary function, for example, auto regulation of retinal capillaries [20].
The tyrosine kinase platelet-derived growth factor receptor beta (PDGFR-[beta]) on pericytes regulates postnatal angiogenesis, lymphangiogenesis, mesangial and vascular smooth muscle cell proliferation, and pericyte recruitment to capillaries.