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Cancer in Children: An Overview

Your child has been diagnosed with cancer. You are likely feeling shocked and scared. These feelings are normal, but remember you are not alone. Support and treatment are available. Your child’s healthcare team will help you and your child every step of the way.

What is cancer?

Cancer is a disease in which the body’s cells grow abnormally. Normally, cells grow at a steady rate. But with cancer, the cells grow out of control and crowd out normal cells. With some cancers, the cells join together and form a lump of tissue called a tumor:



    Cancer occurs when normal cells begin to grow abnormally.

What causes cancer?

Unlike cancer in adults, the cause of cancer in children is often not known. Parents of children with cancer often blame themselves, but cancer in children is no one’s fault. Changes in certain genes, called mutations, may affect the way your child’s cells grow. This gene mutation is random and couldn’t have been prevented. In rare cases, other factors play a role. These include exposure to certain viruses, chemicals, or radiation. It is very rare that cancer in children may be hereditary and may be more likely to happen in certain families.

What are the symptoms of cancer?

There is no single set of symptoms for cancer. Instead, your child’s symptoms depend on what type of cancer it is and where the cancer is found.

How is cancer diagnosed?

Your child may have had a number of imaging or blood tests to diagnose cancer. More tests still may be needed. Often a biopsy, a sample of the tumor, may be removed and checked in a lab. Your healthcare team can tell you more about any tests your child needs.

What is staging and grading?


  • Where the primary tumor is

  • How big the tumor is and how many there are


  • How abnormal the cancer cells look under a microscope

For many cancers, the stages are written as Roman numerals and can have a value of I through IV (1 through 4). The stage numbers refer to how big the tumor is and how much it has spread. For instance, stage I is an early stage of cancer. It means the cancer has not spread to other parts of the body. A stage IV cancer is the most widespread. Many cancers are broken down into further classifications. Your healthcare provider can tell you more if needed and answer any questions you have about the stage of your child’s cancer.

How is cancer treated?

Childhood cancers are often more curable than cancer in adults. The goal of treatment is to attack the abnormal cells, while hurting as few of the healthy cells as possible. To treat the cancer, your child may need more than 1 therapy. These may include the following:

  • Chemotherapy kills cancer cells or shrinks tumors using strong medicine. This treatment often requires several sessions and has side effects. These side effects can include tiredness, hair loss, nausea, and vomiting. There are medicines available to help treat certain side effects.

  • Surgery removes all or part of a tumor.

  • Radiation kills cancer cells or shrinks tumors using high-energy waves, such as X-ray.


What is the likely outcome for my child?

The likelihood of cure may depend on the following:

  • The presence of symptoms related to the type of cancer

  • Type and stage of the cancer


  • The look of the cancer cells under a microscope

  • If the cancer has spread

  • The child’s age and overall health

  • The cancer’s response to treatment

  • Your child's response to medicines, procedures, or therapies



Online Medical Reviewer: Adam Levy MD
Online Medical Reviewer: L Renee Watson MSN RN
Online Medical Reviewer: Rita Sather RN
Date Last Reviewed: 12/1/2021
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