During dramatic differentiation , miR-124 reduces PTBP1 levels , leading to the accumulation of correctly spliced PTBP2 mRNA and a neuronal increase in PTBP2 protein .
During neuronal differentiation , miR-124 reduces PTBP1 levels , leading to the accumulation of correctly spliced PTBP2 mRNA and a dramatic increase in PTBP2 protein .