CC(C)(C)NCC(O)COc1cccc2c1CC(O)C(O)C2
CC(C)(C)NCC(O)COc1cccc2c1CC(O)C(O)C2
8-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell effective permeability.
Constraint: You must select all options from a, b, c, d, or e without using any additional words.
Options:
a: CC(C)NC[C@@H](O)COc1ccc(CCOCC2CC2)cc1
b: CC(C)(C)NCC(O)COc1cccc2c1CC(O)C(O)C2
c: CC(C)(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1
d: CN(C)CC/C=C1/c2ccccc2Sc2ccc(Cl)cc21
e: CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1
Answer: b