O=C(NC1(C(=O)N[C@H](Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccc(C(F)(F)F)cc2s1
O=C(NC1(C(=O)N[C@H](Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccc(C(F)(F)F)cc2s1
N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-6-(trifluoromethyl)-1-benzothiophene-2-carboxamide
User: Can you {#tell me|derive|estimate!} the {permeability__names__noun} for the molecule with the {SMILES__description} {SMILES#}?
Assistant: Based on my analysis, the {permeability__names__noun} for this molecule is approximately {permeability#} {permeability__units}.
User: Can you tell me the Caco-2 cell effective permeability for the molecule with the SMILES O=C(NC1(C(=O)N[C@H](Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccc(C(F)(F)F)cc2s1?
Assistant: Based on my analysis, the Caco-2 cell effective permeability for this molecule is approximately -5.192 cm/s.