FC(F)(F)c1cccc(C2=CCN(CCc3ccc4ccccc4c3)CC2)c1
FC(F)(F)c1cccc(C2=CCN(CCc3ccc4ccccc4c3)CC2)c1
1-(2-naphthalen-2-ylethyl)-4-[3-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, or d without using any additional words.
Options:
a. C[C@@H]1O[C@@H](Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@@H](O)[C@H](O)[C@@H]1O
b. FC(F)(F)c1cccc(C2=CCN(CCc3ccc4ccccc4c3)CC2)c1
c. CN1CC(=O)NC1=N
d. O=C(CS)NCCCCCC(=O)Nc1cccc2cccnc12
Answer: b