CC(CO)NC(=O)C1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1
CC(CO)NC(=O)C1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1
N-(1-hydroxypropan-2-yl)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, d, or e without using any other words.
Options:
a. COC(=O)c1c(Cl)cc(Cl)cc1-c1ccc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
b. CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23)CC1
c. O=C(O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12
d. CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(CCF)c3c2F)CC1
e. CC(CO)NC(=O)C1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1
Answer: e