NC(N)=NC(=O)c1nc(Cl)c(N)nc1N
NC(N)=NC(=O)c1nc(Cl)c(N)nc1N
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell permeability.
Constraint: You must select all options from a, b, c, d, or e without using any other words.
Options:
a) CN(C)[C@@H]1C(=O)C(C(N)=O)=C(O)[C@@]2(O)C(=O)C3=C(O)c4c(O)ccc(Cl)c4[C@@](C)(O)[C@H]3C[C@@H]12
b) O=C(NC1(C(=O)N[C@H](Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccc(C(F)(F)F)cc2s1
c) c1ccncc1
d) COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2C)cc1OC
e) NC(N)=NC(=O)c1nc(Cl)c(N)nc1N
Answer: e