CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, or d without using any additional words.
Options:
a: CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
b: COCCOCCOC(=O)[C@H](Cc1ccc(OC(=O)N(C)C)cc1)NC(=O)[C@H]1N(S(=O)(=O)c2cnn(C)c2)CSC1(C)C
c: COc1ccc(CCN(C)CCC[C@](C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC
d: O=C(O)CCc1nc(-c2ccccc2)c(-c2ccccc2)o1
Answer: a