COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell effective permeability.
Constraint: You must select all options from a, b, c, or d without using any other words.
Options:
(a) COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
(b) CC(C)NS(=O)(=O)n1c(N)nc2ccc(C(C(N)=O)c3cccc(F)c3)cc21
(c) CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1
(d) CCCCCCCCCC(=O)OC
Answer: a