Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N[C@H]1C
Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N[C@H]1C
(2R)-7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should it be a special {#molecule|one!}?
User: Yes, the molecule should have a {permeability__names__noun} value close to {permeability#} {permeability__units}.
Assistant: {#Understood|Got it|Ok!}, this {SMILES__description} has a {permeability__names__noun} value of approximately {permeability#} {permeability__units}: {SMILES#}
User: I want to create a SMILES.
Assistant: This sounds very exciting. Should it be a special one?
User: Yes, the molecule should have a Caco-2 cell effective permeability value close to -5.305 cm/s.
Assistant: Understood, this SMILES has a Caco-2 cell effective permeability value of approximately -5.305 cm/s: Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N[C@H]1C