CCCCCCC(N)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
CCCCCCC(N)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
(2R)-N-[(2S)-1-[[(2S)-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxidanylidene-propan-2-yl]-1-[(2S)-2-(2-azanyloctanoylamino)-3-(2,6-dimethyl-4-oxidanyl-phenyl)propanoyl]pyrrolidine-2-carboxamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, d, or e without using any additional words.
Options:
a) CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1
b) Clc1ccncc1
c) CCCCCCC(N)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
d) C/C=C\C=C/CC/C=C/C=C/C(=O)NCC(C)C
e) COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1ccc2c(c1)OCO2)c1cn(C)c2cc(C#N)ccc12
Answer: c