COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should have a {permeability__names__noun} value of approximately {permeability#} {permeability__units}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} has a {permeability__names__noun} value of approximately {permeability#} {permeability__units}: {SMILES#}
User: I want to come up with a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should have a Caco-2 cell permeability value of approximately -5.640 cm/s.
Assistant: Ok, this SMILES has a Caco-2 cell permeability value of approximately -5.640 cm/s: COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC