O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccncc1
O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccncc1
2-(pyridin-4-ylmethylamino)-N-[3-(trifluoromethyl)phenyl]benzamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, or d without using any additional words.
Options:
a. O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccncc1
b. CCCCCCCCCC(=O)Nc1ccc(S(=O)(=O)Nc2nncs2)cc1
c. CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1
d. Cn1c(N2CCN(CCCN3c4ccccc4Sc4ccc(CCC(=O)O)cc43)CC2)cc(=O)n(C)c1=O
Answer: a