COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, d, or e without using any other words.
Options:
a) COc1cc(C(=O)NCc2ccc(OCCN(C)C)cc2)cc(OC)c1OC
b) COc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341
c) C[C@H](CS)C(=O)N1CCC[C@@H]1C(=O)O
d) Cc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1C(F)(F)F
e) CCOC(=O)[C@H](Cc1ccc(OC(=O)N(C)C)cc1)NC(=O)[C@H]1N(S(=O)(=O)c2cnn(C)c2)CSC1(C)C
Answer: b