Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 permeability.
Constraint: You must select all options from a, b, c, d, or e without using any additional words.
Options:
a: O=C(O)COc1ccc(C(=O)CN2CCN(C3CCNCC3)CC2=O)cc1
b: CN(C)CCC=C1c2ccccc2CCc2ccccc21
c: CCCCOc1cccc(NC(=O)OCCN2CCCC2)c1
d: Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
e: Cc1c(N(C)C)c(=O)n(-c2ccccc2)n1C
Answer: d