Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 permeability.
Constraint: You must select all options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
b CCO[C@H](CCC(C)(C)O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@@]4(C)C3CC[C@]12C
c CC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1O
d CC(C)NC[C@@H](O)COc1ccc(CCOCC2CC2)cc1
e CCCCCOc1cccc(NC(=O)OCCN2CCCC2)c1
Answer: a