CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
[2-butyl-5-chloranyl-3-[[4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 permeability.
Constraint: You must select all options from a, b, c, d, or e without using any other words.
Options:
[a] Clc1ccc(C2CN3CCN=C3c3ccccc32)cc1
[b] CC(C)(C)c1nn2ccccc2c1Cc1ccc(C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)cc1
[c] CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
[d] CC(C)NC[C@@H](O)COc1ccc(CCOCC2CC2)cc1
[e] CC(C)(C)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1
Answer: c