Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1
Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1
N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, or d without using any other words.
Options:
(a) Cc1c(O)c(=O)ccn1C
(b) CN(CC(=O)O)C(=O)CN
(c) CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
(d) Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1
Answer: d