COC(=O)c1c(Cl)cc(Cl)cc1-c1cnc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
COC(=O)c1c(Cl)cc(Cl)cc1-c1cnc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
methyl 2,4-dichloro-6-[5-fluoro-6-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]pyridin-3-yl]benzoate
Task: Please predict a property for a molecule based on the description.
Description: Predict the {permeability__names__noun}.
{#Molecule |!}{SMILES__description}: {SMILES#}
Constraint: Answer the question in a {#full|complete!} sentence.
Result: This molecule has a {permeability__names__noun} of {permeability#} {permeability__units}.
Task: Please predict a property for a molecule based on the description.
Description: Predict the Caco-2 permeability.
Molecule SMILES: COC(=O)c1c(Cl)cc(Cl)cc1-c1cnc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
Constraint: Answer the question in a full sentence.
Result: This molecule has a Caco-2 permeability of -4.538 cm/s.