CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, or d without using any other words.
Options:
(a) C[C@H](N[C@H](CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@@H]1C(=O)O
(b) COc1ccc2[nH]c(S(=O)Cc3ncc(C)c(OC)c3C)nc2c1
(c) CN1C(=O)CC(N2CCN(CC/C=C3/c4ccccc4COc4ccc(C(=O)O)cc43)CC2)N(C)C1=O
(d) CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
Answer: d