Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell permeability?
Constraint: Even if you are uncertain, you must pick either a, b, or c without using any other words.
Options:
a. Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
b. Cc1ccc(N2CCN(C(=O)[C@H](C)Cc3ccc(Cl)cc3)CC2)c([C@@H](NC(=O)CCN)C(C)C)c1
c. NC(CC(=O)O)C(=O)OC[C@@H]1O[C@H](n2cc(F)c(=O)[nH]c2=O)C[C@H]1O
Answer: a