COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, d, or e without using any additional words.
Options:
a) NC(N)=NC(=O)c1nc(Cl)c(N)nc1N
b) CCCCCCCCCC(=O)O
c) O=C(NC1(C(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1cc2ccccc2s1
d) COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
e) Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2NC1C
Answer: d