Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
2-[(7-methyl-1H-imidazo[4,5-b]pyridin-2-yl)methyl]-3H-benzimidazole-5-carboximidamide
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell permeability.
Constraint: You must select all options from a, b, c, or d without using any other words.
Options:
a. Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
b. NC(Cc1ccccc1)C(=O)OC[C@@H]1O[C@H](n2cc(F)c(=O)[nH]c2=O)C[C@H]1O
c. C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO
d. CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(C)C(=O)NCC(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(C)C(N)=O
Answer: a