CN1C(=O)CC(N2CCN(CC/C=C3/c4ccccc4COc4ccc(CC(=O)O)cc43)CC2)N(C)C1=O
CN1C(=O)CC(N2CCN(CC/C=C3/c4ccccc4COc4ccc(CC(=O)O)cc43)CC2)N(C)C1=O
2-[(11Z)-11-[3-[4-[1,3-dimethyl-2,6-bis(oxidanylidene)-1,3-diazinan-4-yl]piperazin-1-yl]propylidene]-6H-benzo[c][1]benzoxepin-2-yl]ethanoicacid
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell effective permeability.
Constraint: You must select all options from a, b, or c without using any other words.
Options:
[a] C=C(c1ccccc1)[C@H]1OC[C@@H](N)[C@H](C)O1
[b] CN1C(=O)CC(N2CCN(CC/C=C3/c4ccccc4COc4ccc(CC(=O)O)cc43)CC2)N(C)C1=O
[c] CC(C(=O)O)c1ccc2c(c1)Cc1cccnc1O2
Answer: b