Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
2-[(7-methyl-1H-imidazo[4,5-b]pyridin-2-yl)methyl]-3H-benzimidazole-5-carboximidamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, d, or e without using any other words.
Options:
a.) Cc1nc(-c2c(Cl)cc(Cl)cc2-c2ccc([C@@H](C)NC(=O)C3(NC(=O)C(F)(F)F)CC3)c(F)c2)no1
b.) COC(=O)C(C)NP(=O)(OC[C@@H]1C=C[C@H](n2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(OC)cc1
c.) O=C(O)CC(CC1CCN(C(=O)CCc2ccc3c(n2)NCCC3)CC1)c1cnc2ccccc2c1
d.) Cc1ccnc2nc(Cc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c12
e.) O=c1c(OC2C(O)OC(CO)C(O)C2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
Answer: d