O=C1CN=C(c2ccccn2)c2cc(Br)ccc2N1
O=C1CN=C(c2ccccn2)c2cc(Br)ccc2N1
7-bromo-5-pyridin-2-yl-1,3-dihydro-1,4-benzodiazepin-2-one
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, or d without using any additional words.
Options:
a: NCc1cccc(Cc2ncccn2)c1
b: O=C1CN=C(c2ccccn2)c2cc(Br)ccc2N1
c: CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21
d: O=c1cc(-c2ccccc2)oc2ccccc12
Answer: b