COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 permeability?
Constraint: Even if you are uncertain, you must pick either a, b, or c without using any additional words.
Options:
[a] C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12
[b] COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC
[c] C[C@H](N)C(=O)O
Answer: b