CCC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1
CCC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1
2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest {permeability__names__noun}.
Constraint: You must select all options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
Task: Please answer the multiple choice question.
Question: Rank these molecules from lowest to highest Caco-2 cell effective permeability.
Constraint: You must select all options from a, b, c, d, or e without using any additional words.
Options:
a) COC(=O)/C=C/CNC(=O)CN1C(=O)[C@@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)N=C(c2ccccc2)c2ccccc21
b) CNC(=N)c1cccc(CC(CC(=O)N2CCC(C)CC2)NS(=O)(=O)c2ccc3ccccc3c2)c1
c) COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5/C=C\CCCCN(C)C(=O)[C@@H]4C3)cc(-c3cccc(C(C)C)n3)nc2c1C
d) Cn1c(N)nc2ncc(-c3ccccc3)cc21
e) CCC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1
Answer: e