Cn1cncc1CN1CC(N(Cc2cccc(-n3cccc3)c2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21
Cn1cncc1CN1CC(N(Cc2cccc(-n3cccc3)c2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21
N-[6-cyano-1-[(3-methylimidazol-4-yl)methyl]-3,4-dihydro-2H-quinolin-3-yl]-N-[(3-pyrrol-1-ylphenyl)methyl]pyridine-2-sulfonamide
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should have a {permeability__names__noun} value of approximately {permeability#} {permeability__units}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} has a {permeability__names__noun} value of approximately {permeability#} {permeability__units}: {SMILES#}
User: I want to come up with a SMILES.
Assistant: This sounds very interesting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should have a Caco-2 cell permeability value of approximately -5.639 cm/s.
Assistant: Got it, here you go, this SMILES has a Caco-2 cell permeability value of approximately -5.639 cm/s: Cn1cncc1CN1CC(N(Cc2cccc(-n3cccc3)c2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21