{"action":"closed","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/6189","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/6189/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/6189/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/6189/events","html_url":"https://github.com/geneontology/go-ontology/issues/6189","id":97173154,"number":6189,"title":"TPV for ncRNA polyadenylation","user":{"login":"gocentral","id":12972975,"avatar_url":"https://avatars.githubusercontent.com/u/12972975?v=3","gravatar_id":"","url":"https://api.github.com/users/gocentral","html_url":"https://github.com/gocentral","followers_url":"https://api.github.com/users/gocentral/followers","following_url":"https://api.github.com/users/gocentral/following{/other_user}","gists_url":"https://api.github.com/users/gocentral/gists{/gist_id}","starred_url":"https://api.github.com/users/gocentral/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/gocentral/subscriptions","organizations_url":"https://api.github.com/users/gocentral/orgs","repos_url":"https://api.github.com/users/gocentral/repos","events_url":"https://api.github.com/users/gocentral/events{/privacy}","received_events_url":"https://api.github.com/users/gocentral/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/auto-migrated","name":"auto-migrated","color":"ededed"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/RNA%20processes","name":"RNA processes","color":"ededed"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/SGD","name":"SGD","color":"bfd4f2"}],"state":"closed","locked":false,"assignee":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"milestone":null,"comments":15,"created_at":"2009-06-04T21:11:54Z","updated_at":"2015-09-25T16:51:48Z","closed_at":"2015-09-25T16:51:48Z","body":"Hi,\r\n\r\nI'm looking at the tree for \"ncRNA polyadenylation\" \\(GO:0043629\\) and notice that it is under \"RNA 3'-end processing\". However, polyadenylation \\(pA\\) of ncRNAs is not necessarily part of producing a mature RNA, but is often the initial step in degradation. I think the tricky bit is that the exosome and TRAMP complex which perform the catabolism of various RNAs in the nucleus are also involved in 3'-end processing of a variety of RNAs, and it may be that the pA step occurs in 3'-end processing too. \r\n\r\nPerhaps moving \"RNA polyadenylation\" to be a direct child of \"RNA metabolic process\" would help. Then \"ncRNA polyadenlyation\" could have it's parentage under \"ncRNA 3'-end processing\" removed. It already has a child term \"ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process\". If it becomes clear that the pA step is also occurring in ncRNA 3'-end processing, a parallel term for something like \"ncRNA polyadenylation during polyadenylation-dependent ncRNA 3'-end processing\" could be added.\r\n\r\nHowever, I suspect that it may not be completely true for \"mRNA  polyadenylation\" to be under \"RNA 3'-end processing\" either. While it is true that mRNA pA occurs as part of mRNA 3'-end processing, I think that pA of mRNAs, or at least of pre-mRNAs also occurs as part of RNA surveillance and degradation to prevent incorrectly formed mRNAs from leaving the nucleus.\r\n\r\n-Karen\r\n\n\nReported by: krchristie\n\nOriginal Ticket: [geneontology/ontology-requests/6208](https://sourceforge.net/p/geneontology/ontology-requests/6208)"}}