{"action":"closed","issue":{"url":"https://api.github.com/repos/veg/hyphy/issues/290","labels_url":"https://api.github.com/repos/veg/hyphy/issues/290/labels{/name}","comments_url":"https://api.github.com/repos/veg/hyphy/issues/290/comments","events_url":"https://api.github.com/repos/veg/hyphy/issues/290/events","html_url":"https://github.com/veg/hyphy/issues/290","id":78088687,"number":290,"title":"Estimating branch-by-branch variation in rates Analysis","user":{"login":"francicco","id":9006870,"avatar_url":"https://avatars.githubusercontent.com/u/9006870?v=3","gravatar_id":"","url":"https://api.github.com/users/francicco","html_url":"https://github.com/francicco","followers_url":"https://api.github.com/users/francicco/followers","following_url":"https://api.github.com/users/francicco/following{/other_user}","gists_url":"https://api.github.com/users/francicco/gists{/gist_id}","starred_url":"https://api.github.com/users/francicco/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/francicco/subscriptions","organizations_url":"https://api.github.com/users/francicco/orgs","repos_url":"https://api.github.com/users/francicco/repos","events_url":"https://api.github.com/users/francicco/events{/privacy}","received_events_url":"https://api.github.com/users/francicco/received_events","type":"User","site_admin":false},"labels":[],"state":"closed","locked":false,"assignee":null,"milestone":null,"comments":0,"created_at":"2015-05-19T13:31:01Z","updated_at":"2015-05-24T12:56:46Z","closed_at":"2015-05-24T12:56:46Z","body":"Dears,\r\n\r\nI'm very new to this kind of analysis and I'd like to have some help, basically on how to perform some analysis. I already dowloaded HyPhy (I'm currently trying to install it on a computer cluster) and read both pdf in the help folder (Theory and practice).\r\n\r\nI come to the point. I have a bunch of alined sequences for ~ 20 closely related species and I'd like to test for positive and diversify selection both looking at branch-by-branch variation, also specifying a particular branch and then looking for site-by-site variation.\r\n\r\nMay somebody help me to shed some light on the issue.\r\nThanks a lot for you helpfulness\r\nbest\r\nFrancesco"}}