{"action":"created","issue":{"url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/116","labels_url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/116/labels{/name}","comments_url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/116/comments","events_url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/116/events","html_url":"https://github.com/clingen-data-model/clingen-data-model/issues/116","id":86683877,"number":116,"title":"SimpleAlleleReglationshipType 'sequentially_related_to question","user":{"login":"larrybabb","id":959003,"avatar_url":"https://avatars.githubusercontent.com/u/959003?v=3","gravatar_id":"","url":"https://api.github.com/users/larrybabb","html_url":"https://github.com/larrybabb","followers_url":"https://api.github.com/users/larrybabb/followers","following_url":"https://api.github.com/users/larrybabb/following{/other_user}","gists_url":"https://api.github.com/users/larrybabb/gists{/gist_id}","starred_url":"https://api.github.com/users/larrybabb/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/larrybabb/subscriptions","organizations_url":"https://api.github.com/users/larrybabb/orgs","repos_url":"https://api.github.com/users/larrybabb/repos","events_url":"https://api.github.com/users/larrybabb/events{/privacy}","received_events_url":"https://api.github.com/users/larrybabb/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":{"login":"srynobio","id":1106139,"avatar_url":"https://avatars.githubusercontent.com/u/1106139?v=3","gravatar_id":"","url":"https://api.github.com/users/srynobio","html_url":"https://github.com/srynobio","followers_url":"https://api.github.com/users/srynobio/followers","following_url":"https://api.github.com/users/srynobio/following{/other_user}","gists_url":"https://api.github.com/users/srynobio/gists{/gist_id}","starred_url":"https://api.github.com/users/srynobio/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/srynobio/subscriptions","organizations_url":"https://api.github.com/users/srynobio/orgs","repos_url":"https://api.github.com/users/srynobio/repos","events_url":"https://api.github.com/users/srynobio/events{/privacy}","received_events_url":"https://api.github.com/users/srynobio/received_events","type":"User","site_admin":false},"milestone":null,"comments":2,"created_at":"2015-06-09T18:07:47Z","updated_at":"2015-06-10T12:11:43Z","closed_at":null,"body":"I'm not sure if we support this relationship type in the current version of the model.  Please provide an example of its use to clarify."},"comment":{"url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/comments/110724468","html_url":"https://github.com/clingen-data-model/clingen-data-model/issues/116#issuecomment-110724468","issue_url":"https://api.github.com/repos/clingen-data-model/clingen-data-model/issues/116","id":110724468,"user":{"login":"larrybabb","id":959003,"avatar_url":"https://avatars.githubusercontent.com/u/959003?v=3","gravatar_id":"","url":"https://api.github.com/users/larrybabb","html_url":"https://github.com/larrybabb","followers_url":"https://api.github.com/users/larrybabb/followers","following_url":"https://api.github.com/users/larrybabb/following{/other_user}","gists_url":"https://api.github.com/users/larrybabb/gists{/gist_id}","starred_url":"https://api.github.com/users/larrybabb/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/larrybabb/subscriptions","organizations_url":"https://api.github.com/users/larrybabb/orgs","repos_url":"https://api.github.com/users/larrybabb/repos","events_url":"https://api.github.com/users/larrybabb/events{/privacy}","received_events_url":"https://api.github.com/users/larrybabb/received_events","type":"User","site_admin":false},"created_at":"2015-06-10T12:11:43Z","updated_at":"2015-06-10T12:11:43Z","body":"I want to understand this more.  Can you provide an example?  And, can we\nadd some more documentation and possible sample scenarios to the\ndocumentation so it is clear how and when this value would be used in\npractice?\n\nIf these are two canonically equivalent simple alleles, then they should be\naggregated by having a common relationship to the same canonical allele.  If\nthis is the case, then we do not need to wire together the simple alleles\nindividually.  If it is different then we should clarify how this would be\ndifferent then canonically equivalent alleles.  Also, verify that if this\nrelationship is conveyed in the underlying conceptual model as well.\nCurrently, the only simple allele relationship in the conceptual model is\nbetween transcript and amino acid alleles.  There is nothing that represents\na relationship between two nucleotide simple alleles as of yet.\n\nFrom:  Shawn Rynearson <notifications@github.com>\nReply-To:  clingen-data-model/clingen-data-model\n<reply+000ea21b9565c1619e5cc1ee87d0072f462c6a9c864c92d492cf00000001118f28079\n2a169ce052ab0e5@reply.github.com>\nDate:  Tuesday, June 9, 2015 6:17 PM\nTo:  clingen-data-model/clingen-data-model\n<clingen-data-model@noreply.github.com>\nCc:  Lawrence Babb <larry.babb@gmail.com>\nSubject:  Re: [clingen-data-model] SimpleAlleleReglationshipType\n'sequentially_related_to question (#116)\n\n\nI added it last as a way to show a relationship between to simple alleles of\nthe same type e.g. two simpleAlleles that denote the same change type, but\nare two separate recorded changes.\n\nCanonicalAllele\n\n\nReply to this email directly or view it on GitHub\n<https://github.com/clingen-data-model/clingen-data-model/issues/116#issueco\nmment-110521032> .\n\n \n   \n \n\n\n"}}