{"action":"created","issue":{"url":"https://api.github.com/repos/pombase/fypo/issues/2294","labels_url":"https://api.github.com/repos/pombase/fypo/issues/2294/labels{/name}","comments_url":"https://api.github.com/repos/pombase/fypo/issues/2294/comments","events_url":"https://api.github.com/repos/pombase/fypo/issues/2294/events","html_url":"https://github.com/pombase/fypo/issues/2294","id":100338237,"number":2294,"title":"PMID:25417108","user":{"login":"Antonialock","id":12727506,"avatar_url":"https://avatars.githubusercontent.com/u/12727506?v=3","gravatar_id":"","url":"https://api.github.com/users/Antonialock","html_url":"https://github.com/Antonialock","followers_url":"https://api.github.com/users/Antonialock/followers","following_url":"https://api.github.com/users/Antonialock/following{/other_user}","gists_url":"https://api.github.com/users/Antonialock/gists{/gist_id}","starred_url":"https://api.github.com/users/Antonialock/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/Antonialock/subscriptions","organizations_url":"https://api.github.com/users/Antonialock/orgs","repos_url":"https://api.github.com/users/Antonialock/repos","events_url":"https://api.github.com/users/Antonialock/events{/privacy}","received_events_url":"https://api.github.com/users/Antonialock/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":1,"created_at":"2015-08-11T15:26:50Z","updated_at":"2015-08-12T10:27:21Z","closed_at":null,"body":"1. abnormal RNA polymerase II release at rDNA \r\n2. abnormal RNA polymerase II release at tDNA \r\n3. abnormal RNA polymerase II release at highly transcribed protein-coding gene \r\n4. decreased antisense transcription-derived small RNA level at tDNA \r\n5. decreased antisense transcription-derived small RNA level at rDNA \r\n6. increased antisense small RNA at rDNA  \t\r\n7. increased number of Rad52 foci at rDNA replication origins \r\n8. increased number of Rad52 foci at rDNA replication pause sites \r\n9. decreased number of Rad52 foci at highly transcribed protein coding genes \r\n10. increased level of DNA:RNA hybrids at rDNA \r\n11. stable shortened rDNA during veg growth\r\n12. progressively shortening rDNA through meiotic generations \r\n13. normal rDNA copy number "},"comment":{"url":"https://api.github.com/repos/pombase/fypo/issues/comments/130250989","html_url":"https://github.com/pombase/fypo/issues/2294#issuecomment-130250989","issue_url":"https://api.github.com/repos/pombase/fypo/issues/2294","id":130250989,"user":{"login":"mah11","id":5196259,"avatar_url":"https://avatars.githubusercontent.com/u/5196259?v=3","gravatar_id":"","url":"https://api.github.com/users/mah11","html_url":"https://github.com/mah11","followers_url":"https://api.github.com/users/mah11/followers","following_url":"https://api.github.com/users/mah11/following{/other_user}","gists_url":"https://api.github.com/users/mah11/gists{/gist_id}","starred_url":"https://api.github.com/users/mah11/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/mah11/subscriptions","organizations_url":"https://api.github.com/users/mah11/orgs","repos_url":"https://api.github.com/users/mah11/repos","events_url":"https://api.github.com/users/mah11/events{/privacy}","received_events_url":"https://api.github.com/users/mah11/received_events","type":"User","site_admin":false},"created_at":"2015-08-12T10:27:21Z","updated_at":"2015-08-12T10:27:21Z","body":"a few questions:\r\n\r\nIs \"RNA polymerase II release\" distinct from \"termination of RNA polymerase II transcription\" (a la GO:0006369)?\r\n\r\n\"Antisense transcription-derived small RNA\" sounds the same as \"antisense small RNA\", only wordier. OK if I use the \"antisense small RNA\" wording in the names for 4-6?\r\n\r\nDoes \"shortened rDNA\" mean \"decreased rDNA copy number\"?"}}