{"action":"created","issue":{"url":"https://api.github.com/repos/isovic/graphmap/issues/7","labels_url":"https://api.github.com/repos/isovic/graphmap/issues/7/labels{/name}","comments_url":"https://api.github.com/repos/isovic/graphmap/issues/7/comments","events_url":"https://api.github.com/repos/isovic/graphmap/issues/7/events","html_url":"https://github.com/isovic/graphmap/issues/7","id":102151177,"number":7,"title":"Turn terminal deletions into soft clips","user":{"login":"andreas-wilm","id":1095945,"avatar_url":"https://avatars.githubusercontent.com/u/1095945?v=3","gravatar_id":"","url":"https://api.github.com/users/andreas-wilm","html_url":"https://github.com/andreas-wilm","followers_url":"https://api.github.com/users/andreas-wilm/followers","following_url":"https://api.github.com/users/andreas-wilm/following{/other_user}","gists_url":"https://api.github.com/users/andreas-wilm/gists{/gist_id}","starred_url":"https://api.github.com/users/andreas-wilm/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/andreas-wilm/subscriptions","organizations_url":"https://api.github.com/users/andreas-wilm/orgs","repos_url":"https://api.github.com/users/andreas-wilm/repos","events_url":"https://api.github.com/users/andreas-wilm/events{/privacy}","received_events_url":"https://api.github.com/users/andreas-wilm/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/isovic/graphmap/labels/enhancement","name":"enhancement","color":"84b6eb"}],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":3,"created_at":"2015-08-20T14:25:00Z","updated_at":"2015-08-21T01:53:15Z","closed_at":null,"body":"I got a bunch of sequences that get aligned with leading (trailing not observed) deletions e.g. 50D740M1D1M1D2M. Terminal indels don't make sense in an alignment (after all: how do you distinguish between a terminal insertion or deletion?). They should be soft clipped. "},"comment":{"url":"https://api.github.com/repos/isovic/graphmap/issues/comments/133244685","html_url":"https://github.com/isovic/graphmap/issues/7#issuecomment-133244685","issue_url":"https://api.github.com/repos/isovic/graphmap/issues/7","id":133244685,"user":{"login":"andreas-wilm","id":1095945,"avatar_url":"https://avatars.githubusercontent.com/u/1095945?v=3","gravatar_id":"","url":"https://api.github.com/users/andreas-wilm","html_url":"https://github.com/andreas-wilm","followers_url":"https://api.github.com/users/andreas-wilm/followers","following_url":"https://api.github.com/users/andreas-wilm/following{/other_user}","gists_url":"https://api.github.com/users/andreas-wilm/gists{/gist_id}","starred_url":"https://api.github.com/users/andreas-wilm/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/andreas-wilm/subscriptions","organizations_url":"https://api.github.com/users/andreas-wilm/orgs","repos_url":"https://api.github.com/users/andreas-wilm/repos","events_url":"https://api.github.com/users/andreas-wilm/events{/privacy}","received_events_url":"https://api.github.com/users/andreas-wilm/received_events","type":"User","site_admin":false},"created_at":"2015-08-21T01:53:15Z","updated_at":"2015-08-21T01:53:15Z","body":"Here's an example sequence:\r\nACTCCTACGGGAGGCAGCAGTAGGGAATCTTCCGCAATGGACGAAAGTCTGACGGAGCAACGCCGCGTGAGTGATGAAGGCTTTCGGGTCGTAAAACTCTGTTGTTAGGGAAGAACAAGTGCTAGTTGAATAAGCTGGCACCTTGACGGTACCTAACCAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTATCCGGAATTATTGGGCGTAAAGCGCGCGCAGGTGGTTTCTTAAGTCTGATGTGAAAGCCCACGGCTCAACCGTGGAGGGTCATTGGAAACTGGAAACTTGAGTGCAGAAGAGGAAAGTGGAATTCCATGTGTAGCGGTGAAATGCGTAGAGATATGGAGGAACACCAGTGGCGAAGGCGACTTTCTGGTCTGTAACTGACACTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGTCTACTAGGGGTTGGGGCCTTTGAGGCTTTAGTGGCGCAGCTAACGCGATAAGTAGACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGTCTTGACATCCACGGAAGTTTTCAGAGATGAGAATGTGCCTTCGGGAACCGTGAGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGCTG\r\nwhich matches sequence 4453932\twith cigar string\t50D308M1D114M1I86M1D38M1D9M1I21M1I101M1D8M1I48M1D1M1D2M"}}