{"action":"created","issue":{"url":"https://api.github.com/repos/geronimp/graftM/issues/121","labels_url":"https://api.github.com/repos/geronimp/graftM/issues/121/labels{/name}","comments_url":"https://api.github.com/repos/geronimp/graftM/issues/121/comments","events_url":"https://api.github.com/repos/geronimp/graftM/issues/121/events","html_url":"https://github.com/geronimp/graftM/issues/121","id":109418561,"number":121,"title":"graftM create builds an HMM from sequences that have not been deduplicated","user":{"login":"caity-s","id":12855031,"avatar_url":"https://avatars.githubusercontent.com/u/12855031?v=3","gravatar_id":"","url":"https://api.github.com/users/caity-s","html_url":"https://github.com/caity-s","followers_url":"https://api.github.com/users/caity-s/followers","following_url":"https://api.github.com/users/caity-s/following{/other_user}","gists_url":"https://api.github.com/users/caity-s/gists{/gist_id}","starred_url":"https://api.github.com/users/caity-s/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/caity-s/subscriptions","organizations_url":"https://api.github.com/users/caity-s/orgs","repos_url":"https://api.github.com/users/caity-s/repos","events_url":"https://api.github.com/users/caity-s/events{/privacy}","received_events_url":"https://api.github.com/users/caity-s/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":4,"created_at":"2015-10-02T02:14:52Z","updated_at":"2015-10-14T07:21:18Z","closed_at":null,"body":"Hello Ben,\r\n\r\nGraftM create builds the HMM using the sequences provided, and seems to be resulting in an HMM biased to duplicates.\r\n\r\nThanks,\r\nCaitlin"},"comment":{"url":"https://api.github.com/repos/geronimp/graftM/issues/comments/147960235","html_url":"https://github.com/geronimp/graftM/issues/121#issuecomment-147960235","issue_url":"https://api.github.com/repos/geronimp/graftM/issues/121","id":147960235,"user":{"login":"wwood","id":15348,"avatar_url":"https://avatars.githubusercontent.com/u/15348?v=3","gravatar_id":"","url":"https://api.github.com/users/wwood","html_url":"https://github.com/wwood","followers_url":"https://api.github.com/users/wwood/followers","following_url":"https://api.github.com/users/wwood/following{/other_user}","gists_url":"https://api.github.com/users/wwood/gists{/gist_id}","starred_url":"https://api.github.com/users/wwood/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/wwood/subscriptions","organizations_url":"https://api.github.com/users/wwood/orgs","repos_url":"https://api.github.com/users/wwood/repos","events_url":"https://api.github.com/users/wwood/events{/privacy}","received_events_url":"https://api.github.com/users/wwood/received_events","type":"User","site_admin":false},"created_at":"2015-10-14T07:21:18Z","updated_at":"2015-10-14T07:21:18Z","body":"One might argue that diamond sequences shouldn't be deduplicated, because the deduplication happens only for those positions aligned to the HMM, and diamond doesn't care about HMMs. What do you think @geronimp ?"}}