{"action":"opened","issue":{"url":"https://api.github.com/repos/STAT540-UBC/Discussion/issues/25","labels_url":"https://api.github.com/repos/STAT540-UBC/Discussion/issues/25/labels{/name}","comments_url":"https://api.github.com/repos/STAT540-UBC/Discussion/issues/25/comments","events_url":"https://api.github.com/repos/STAT540-UBC/Discussion/issues/25/events","html_url":"https://github.com/STAT540-UBC/Discussion/issues/25","id":56312904,"number":25,"title":"Need help understanding unbiased activation of T cells","user":{"login":"IssamLaradji","id":3382128,"avatar_url":"https://avatars.githubusercontent.com/u/3382128?v=3","gravatar_id":"","url":"https://api.github.com/users/IssamLaradji","html_url":"https://github.com/IssamLaradji","followers_url":"https://api.github.com/users/IssamLaradji/followers","following_url":"https://api.github.com/users/IssamLaradji/following{/other_user}","gists_url":"https://api.github.com/users/IssamLaradji/gists{/gist_id}","starred_url":"https://api.github.com/users/IssamLaradji/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/IssamLaradji/subscriptions","organizations_url":"https://api.github.com/users/IssamLaradji/orgs","repos_url":"https://api.github.com/users/IssamLaradji/repos","events_url":"https://api.github.com/users/IssamLaradji/events{/privacy}","received_events_url":"https://api.github.com/users/IssamLaradji/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":0,"created_at":"2015-02-02T23:58:53Z","updated_at":"2015-02-02T23:58:53Z","closed_at":null,"body":"So I read this paper (http://www.sciencemag.org/content/345/6202/1254665.full) which says in the abstract,\r\n\"We analyzed gene expression in CD4+ T cells during unbiased activation or in T helper 17 (TH17) conditions from 348 healthy participants representing European, Asian, and African ancestries.\"\r\n\r\nWhat does \"unbiased activation\" mean ? is that an activation done to the gene expressions without any stimulants ?\r\n\r\nThanks!\r\n\r\n "}}