{"action":"created","issue":{"url":"https://api.github.com/repos/obophenotype/uberon/issues/693","labels_url":"https://api.github.com/repos/obophenotype/uberon/issues/693/labels{/name}","comments_url":"https://api.github.com/repos/obophenotype/uberon/issues/693/comments","events_url":"https://api.github.com/repos/obophenotype/uberon/issues/693/events","html_url":"https://github.com/obophenotype/uberon/issues/693","id":72388230,"number":693,"title":"new term request: profundal placode","user":{"login":"ANiknejad","id":2682520,"avatar_url":"https://avatars.githubusercontent.com/u/2682520?v=3","gravatar_id":"","url":"https://api.github.com/users/ANiknejad","html_url":"https://github.com/ANiknejad","followers_url":"https://api.github.com/users/ANiknejad/followers","following_url":"https://api.github.com/users/ANiknejad/following{/other_user}","gists_url":"https://api.github.com/users/ANiknejad/gists{/gist_id}","starred_url":"https://api.github.com/users/ANiknejad/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ANiknejad/subscriptions","organizations_url":"https://api.github.com/users/ANiknejad/orgs","repos_url":"https://api.github.com/users/ANiknejad/repos","events_url":"https://api.github.com/users/ANiknejad/events{/privacy}","received_events_url":"https://api.github.com/users/ANiknejad/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":1,"created_at":"2015-05-01T08:57:09Z","updated_at":"2015-05-03T07:03:59Z","closed_at":null,"body":"Hi Chris,\r\n\r\nCurrently we only have this term for 'profundal' stuff:\r\n\r\nid: XAO:0004093\r\nname: profundal placode (Xenopus)\r\n\r\n'profundal placode' sounds to be egal to 'ophtalmic placode'\r\nhttp://www.ncbi.nlm.nih.gov/pubmed/?term=22512454\r\n\" [In vertebrates] The lens placode, which generates the crystalline-containing cells of the lens, is also associated with the forebrain but forms more posteriorly alongside the region of the diencephalon that will give rise to the optic cup. More caudally, the trigeminal placodes, the ophthalmic (or profundal) and maxillomandibular, emerge at the level of the midbrain-hindbrain boundary....clearly distinct profundal and trigeminal placodes giving rise to correspondingly distinct ganglia are readily observable in shark embryos (O’Neill et al. 2007).\"\r\n\r\nIn Uberon we have an 'optic placode' exact synonym of \r\nUBERON:0003071\r\nname: eye primordium\r\n\r\nHowever I guess, that does not match the 'profundal placode' as defined here for Shark\r\nhttp://www.ncbi.nlm.nih.gov/pubmed/?term=17234174\r\n\r\nCheers,\r\n\r\nAnne\r\n\r\n"},"comment":{"url":"https://api.github.com/repos/obophenotype/uberon/issues/comments/98445997","html_url":"https://github.com/obophenotype/uberon/issues/693#issuecomment-98445997","issue_url":"https://api.github.com/repos/obophenotype/uberon/issues/693","id":98445997,"user":{"login":"cmungall","id":50745,"avatar_url":"https://avatars.githubusercontent.com/u/50745?v=3","gravatar_id":"","url":"https://api.github.com/users/cmungall","html_url":"https://github.com/cmungall","followers_url":"https://api.github.com/users/cmungall/followers","following_url":"https://api.github.com/users/cmungall/following{/other_user}","gists_url":"https://api.github.com/users/cmungall/gists{/gist_id}","starred_url":"https://api.github.com/users/cmungall/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/cmungall/subscriptions","organizations_url":"https://api.github.com/users/cmungall/orgs","repos_url":"https://api.github.com/users/cmungall/repos","events_url":"https://api.github.com/users/cmungall/events{/privacy}","received_events_url":"https://api.github.com/users/cmungall/received_events","type":"User","site_admin":false},"created_at":"2015-05-03T07:03:59Z","updated_at":"2015-05-03T07:03:59Z","body":"Interesting. See also: [UBERON:0003070](http://purl.obolibrary.org/obo/UBERON_0003070) ! trigeminal placode\r\n\r\nFigure 9-5 of Butler and Hodos seems to use Profundal as synonymous with trigeminal...  but this may only be true of their distal end; from XAO: \"The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24\""}}