{"action":"created","issue":{"url":"https://api.github.com/repos/broadinstitute/picard/issues/196","labels_url":"https://api.github.com/repos/broadinstitute/picard/issues/196/labels{/name}","comments_url":"https://api.github.com/repos/broadinstitute/picard/issues/196/comments","events_url":"https://api.github.com/repos/broadinstitute/picard/issues/196/events","html_url":"https://github.com/broadinstitute/picard/pull/196","id":68336210,"number":196,"title":"New CLP for downsampling in a way that tries to keep neighboring reads together","user":{"login":"yfarjoun","id":2745554,"avatar_url":"https://avatars.githubusercontent.com/u/2745554?v=3","gravatar_id":"","url":"https://api.github.com/users/yfarjoun","html_url":"https://github.com/yfarjoun","followers_url":"https://api.github.com/users/yfarjoun/followers","following_url":"https://api.github.com/users/yfarjoun/following{/other_user}","gists_url":"https://api.github.com/users/yfarjoun/gists{/gist_id}","starred_url":"https://api.github.com/users/yfarjoun/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/yfarjoun/subscriptions","organizations_url":"https://api.github.com/users/yfarjoun/orgs","repos_url":"https://api.github.com/users/yfarjoun/repos","events_url":"https://api.github.com/users/yfarjoun/events{/privacy}","received_events_url":"https://api.github.com/users/yfarjoun/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":4,"created_at":"2015-04-14T10:41:15Z","updated_at":"2015-04-26T03:06:30Z","closed_at":null,"pull_request":{"url":"https://api.github.com/repos/broadinstitute/picard/pulls/196","html_url":"https://github.com/broadinstitute/picard/pull/196","diff_url":"https://github.com/broadinstitute/picard/pull/196.diff","patch_url":"https://github.com/broadinstitute/picard/pull/196.patch"},"body":"This is intended to mimic to a higher degree the results of sequencing less. The idea is to create a periodic mask of reads based on their location within their tile. The mask is setup in such a way so that the same percentage of reads is removed from the bulk and from the boundaries of each tile, and so that neighboring tiles agree on which part of their shared boundary to keep or remove. \r\n\r\nSince this is based on location, mates (and secondary alignments) are treated equally.\r\n"},"comment":{"url":"https://api.github.com/repos/broadinstitute/picard/issues/comments/96314703","html_url":"https://github.com/broadinstitute/picard/pull/196#issuecomment-96314703","issue_url":"https://api.github.com/repos/broadinstitute/picard/issues/196","id":96314703,"user":{"login":"yfarjoun","id":2745554,"avatar_url":"https://avatars.githubusercontent.com/u/2745554?v=3","gravatar_id":"","url":"https://api.github.com/users/yfarjoun","html_url":"https://github.com/yfarjoun","followers_url":"https://api.github.com/users/yfarjoun/followers","following_url":"https://api.github.com/users/yfarjoun/following{/other_user}","gists_url":"https://api.github.com/users/yfarjoun/gists{/gist_id}","starred_url":"https://api.github.com/users/yfarjoun/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/yfarjoun/subscriptions","organizations_url":"https://api.github.com/users/yfarjoun/orgs","repos_url":"https://api.github.com/users/yfarjoun/repos","events_url":"https://api.github.com/users/yfarjoun/events{/privacy}","received_events_url":"https://api.github.com/users/yfarjoun/received_events","type":"User","site_admin":false},"created_at":"2015-04-26T03:06:30Z","updated_at":"2015-04-26T03:06:30Z","body":"@mcovarr I responded to your comments. Care to take another glance?"}}