{"action":"opened","issue":{"url":"https://api.github.com/repos/iqbal-lab/Mykrobe-predictor/issues/88","labels_url":"https://api.github.com/repos/iqbal-lab/Mykrobe-predictor/issues/88/labels{/name}","comments_url":"https://api.github.com/repos/iqbal-lab/Mykrobe-predictor/issues/88/comments","events_url":"https://api.github.com/repos/iqbal-lab/Mykrobe-predictor/issues/88/events","html_url":"https://github.com/iqbal-lab/Mykrobe-predictor/issues/88","id":108847619,"number":88,"title":"Document special case of Clinda output","user":{"login":"Phelimb","id":629499,"avatar_url":"https://avatars.githubusercontent.com/u/629499?v=3","gravatar_id":"","url":"https://api.github.com/users/Phelimb","html_url":"https://github.com/Phelimb","followers_url":"https://api.github.com/users/Phelimb/followers","following_url":"https://api.github.com/users/Phelimb/following{/other_user}","gists_url":"https://api.github.com/users/Phelimb/gists{/gist_id}","starred_url":"https://api.github.com/users/Phelimb/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/Phelimb/subscriptions","organizations_url":"https://api.github.com/users/Phelimb/orgs","repos_url":"https://api.github.com/users/Phelimb/repos","events_url":"https://api.github.com/users/Phelimb/events{/privacy}","received_events_url":"https://api.github.com/users/Phelimb/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":0,"created_at":"2015-09-29T11:08:42Z","updated_at":"2015-09-29T11:08:42Z","closed_at":null,"body":"The options for Clindamycin output are:\r\n\r\nR(constitutive)\r\nR(inducible)\r\n\r\nr(constitutive)\r\nr(inducible)\r\n\r\nS\r\n\r\nThe \"constitutive\" is implied for all the other drugs and just means that there's a direct relationship between the gene and resistance (the usual case). \r\n\r\nHowever, Clindamycin has a special case. When any of the ERM* genes are present the isolate will become resistant to Clindamycin if first treated with Erythromycin (hence induced) but not otherwise \\cite{}. We have the (constitutive), (inducible) in order to distinguish between these two cases. "}}