{"action":"closed","issue":{"url":"https://api.github.com/repos/genome/civic-client/issues/164","labels_url":"https://api.github.com/repos/genome/civic-client/issues/164/labels{/name}","comments_url":"https://api.github.com/repos/genome/civic-client/issues/164/comments","events_url":"https://api.github.com/repos/genome/civic-client/issues/164/events","html_url":"https://github.com/genome/civic-client/issues/164","id":95458868,"number":164,"title":"add definitions for all options in evidence type, level, direction","user":{"login":"jmcmichael","id":132909,"avatar_url":"https://avatars.githubusercontent.com/u/132909?v=3","gravatar_id":"","url":"https://api.github.com/users/jmcmichael","html_url":"https://github.com/jmcmichael","followers_url":"https://api.github.com/users/jmcmichael/followers","following_url":"https://api.github.com/users/jmcmichael/following{/other_user}","gists_url":"https://api.github.com/users/jmcmichael/gists{/gist_id}","starred_url":"https://api.github.com/users/jmcmichael/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/jmcmichael/subscriptions","organizations_url":"https://api.github.com/users/jmcmichael/orgs","repos_url":"https://api.github.com/users/jmcmichael/repos","events_url":"https://api.github.com/users/jmcmichael/events{/privacy}","received_events_url":"https://api.github.com/users/jmcmichael/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/genome/civic-client/labels/enhancement","name":"enhancement","color":"84b6eb"}],"state":"closed","locked":false,"assignee":{"login":"jmcmichael","id":132909,"avatar_url":"https://avatars.githubusercontent.com/u/132909?v=3","gravatar_id":"","url":"https://api.github.com/users/jmcmichael","html_url":"https://github.com/jmcmichael","followers_url":"https://api.github.com/users/jmcmichael/followers","following_url":"https://api.github.com/users/jmcmichael/following{/other_user}","gists_url":"https://api.github.com/users/jmcmichael/gists{/gist_id}","starred_url":"https://api.github.com/users/jmcmichael/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/jmcmichael/subscriptions","organizations_url":"https://api.github.com/users/jmcmichael/orgs","repos_url":"https://api.github.com/users/jmcmichael/repos","events_url":"https://api.github.com/users/jmcmichael/events{/privacy}","received_events_url":"https://api.github.com/users/jmcmichael/received_events","type":"User","site_admin":false},"milestone":null,"comments":1,"created_at":"2015-07-16T15:24:39Z","updated_at":"2015-08-04T20:23:15Z","closed_at":"2015-08-04T20:23:15Z","body":"These fields should display their extended descriptions after selection (similar to how the Ratings field shows the definitions for each star)\r\n\r\n**Evidence Type**\r\nPredictive - Evidence pertaining to a variant’s effect on therapeutic response\r\nPredictive Evidence Direction:\r\n- Supports: The experiment or study supports this variant’s response to a drug\r\n- Does not support: The experiment or study does not support, or was inconclusive of an interaction between the variant and a drug\r\n\r\nDiagnostic - Evidence pertaining to a variant’s impact on patient diagnosis\r\nDiagnostic Evidence Direction:\r\n- Supports: The experiment or study supports variant’s impact on the diagnosis of disease or subtype\r\n- Does not Support: The experiment or study does not support the variant’s impact on diagnosis of disease or subtype\r\n\r\nPrognostic - Evidence pertaining to a variant’s impact on disease progression, severity, or patient survival\r\nPrognostic Evidence Direction\r\n- Supports: The experiment or study supports a variant’s impact on prognostic outcome\r\n- Does not support: The experiment or study does not support a prognostic association between variant and outcome\r\n\r\n**Evidence Levels**\r\nA - Validated association\r\n- Proven/consensus association in human medicine.\r\n\r\nB - Clinical Evidence\r\n- Clinical trial or other primary patient data supports association.\r\n\r\nC - Preclinical Evidence\r\n- In vivo or in vitro models support association.\r\n\r\nD - Case Study\r\n- Individual case reports from clinical journals.\r\n\r\nE - Inferential Association\r\n- Indirect evidence."}}