{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/12024","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12024/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12024/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12024/events","html_url":"https://github.com/geneontology/go-ontology/issues/12024","id":102352896,"number":12024,"title":" rename ribonucleoside-diphosphate reductase activity","user":{"login":"ValWood","id":7359272,"avatar_url":"https://avatars.githubusercontent.com/u/7359272?v=3","gravatar_id":"","url":"https://api.github.com/users/ValWood","html_url":"https://github.com/ValWood","followers_url":"https://api.github.com/users/ValWood/followers","following_url":"https://api.github.com/users/ValWood/following{/other_user}","gists_url":"https://api.github.com/users/ValWood/gists{/gist_id}","starred_url":"https://api.github.com/users/ValWood/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ValWood/subscriptions","organizations_url":"https://api.github.com/users/ValWood/orgs","repos_url":"https://api.github.com/users/ValWood/repos","events_url":"https://api.github.com/users/ValWood/events{/privacy}","received_events_url":"https://api.github.com/users/ValWood/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/PomBase","name":"PomBase","color":"bfd4f2"}],"state":"closed","locked":false,"assignee":{"login":"ukemi","id":11067494,"avatar_url":"https://avatars.githubusercontent.com/u/11067494?v=3","gravatar_id":"","url":"https://api.github.com/users/ukemi","html_url":"https://github.com/ukemi","followers_url":"https://api.github.com/users/ukemi/followers","following_url":"https://api.github.com/users/ukemi/following{/other_user}","gists_url":"https://api.github.com/users/ukemi/gists{/gist_id}","starred_url":"https://api.github.com/users/ukemi/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ukemi/subscriptions","organizations_url":"https://api.github.com/users/ukemi/orgs","repos_url":"https://api.github.com/users/ukemi/repos","events_url":"https://api.github.com/users/ukemi/events{/privacy}","received_events_url":"https://api.github.com/users/ukemi/received_events","type":"User","site_admin":false},"milestone":null,"comments":8,"created_at":"2015-08-21T10:58:16Z","updated_at":"2015-08-24T12:26:56Z","closed_at":"2015-08-24T11:36:14Z","body":"can we name\r\nribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor\r\nback to \r\nribonucleoside-diphosphate reductase activity\r\nbecause that is what everyone calls it... (well they usually call it ribonuleotide reductase, but this works)\r\n\r\nI ask because I want to request the term\r\nribonucleoside-diphosphate reductase inhibitor  activity\r\n(or even better \r\nand I want it to match the term name it refers to.\r\n\r\nIt also matches the GO complex name\r\nGO:0005971 - ribonucleoside-diphosphate reductase complex\r\n\r\nIf they are not equivalent (currently these are *exact* synonyms), some more complicated solution will be required....\r\n\r\n\r\n\r\n\r\n\r\n\r\n"},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/134171470","html_url":"https://github.com/geneontology/go-ontology/issues/12024#issuecomment-134171470","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12024","id":134171470,"user":{"login":"pgaudet","id":4782928,"avatar_url":"https://avatars.githubusercontent.com/u/4782928?v=3","gravatar_id":"","url":"https://api.github.com/users/pgaudet","html_url":"https://github.com/pgaudet","followers_url":"https://api.github.com/users/pgaudet/followers","following_url":"https://api.github.com/users/pgaudet/following{/other_user}","gists_url":"https://api.github.com/users/pgaudet/gists{/gist_id}","starred_url":"https://api.github.com/users/pgaudet/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/pgaudet/subscriptions","organizations_url":"https://api.github.com/users/pgaudet/orgs","repos_url":"https://api.github.com/users/pgaudet/repos","events_url":"https://api.github.com/users/pgaudet/events{/privacy}","received_events_url":"https://api.github.com/users/pgaudet/received_events","type":"User","site_admin":false},"created_at":"2015-08-24T12:26:55Z","updated_at":"2015-08-24T12:26:55Z","body":"Hi David, Val,\r\n\r\nIn fact there are three types of ribonucleotide reductases: \r\nhttps://en.wikipedia.org/wiki/Ribonucleotide_reductase#Function\r\n\r\nEach organism usually has a single one (Dicty has two different types, as far as I remember, but I think it's rather an exception). \r\n\r\nIs the type of acceptor within the scope of GO ? This seems very mechanistic and has no impact on the biologically-relevant aspects of RNR, ie, the substrate specificity (it acts on all ribonucleotides with similar efficiency), ad its regulation. \r\n\r\nI would be in favor or keeping all these in a single term. There are no annotations to GO:0036175. \r\n\r\nThanks, \r\nPascale\r\n\r\n\r\n\r\n"}}