{"action":"created","issue":{"url":"https://api.github.com/repos/nest/nest-simulator/issues/17","labels_url":"https://api.github.com/repos/nest/nest-simulator/issues/17/labels{/name}","comments_url":"https://api.github.com/repos/nest/nest-simulator/issues/17/comments","events_url":"https://api.github.com/repos/nest/nest-simulator/issues/17/events","html_url":"https://github.com/nest/nest-simulator/pull/17","id":79487888,"number":17,"title":"First Structural Plasticity Pull request, corrected","user":{"login":"sdiazpier","id":12412962,"avatar_url":"https://avatars.githubusercontent.com/u/12412962?v=3","gravatar_id":"","url":"https://api.github.com/users/sdiazpier","html_url":"https://github.com/sdiazpier","followers_url":"https://api.github.com/users/sdiazpier/followers","following_url":"https://api.github.com/users/sdiazpier/following{/other_user}","gists_url":"https://api.github.com/users/sdiazpier/gists{/gist_id}","starred_url":"https://api.github.com/users/sdiazpier/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/sdiazpier/subscriptions","organizations_url":"https://api.github.com/users/sdiazpier/orgs","repos_url":"https://api.github.com/users/sdiazpier/repos","events_url":"https://api.github.com/users/sdiazpier/events{/privacy}","received_events_url":"https://api.github.com/users/sdiazpier/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":3,"created_at":"2015-05-22T15:02:42Z","updated_at":"2015-05-29T14:57:22Z","closed_at":null,"pull_request":{"url":"https://api.github.com/repos/nest/nest-simulator/pulls/17","html_url":"https://github.com/nest/nest-simulator/pull/17","diff_url":"https://github.com/nest/nest-simulator/pull/17.diff","patch_url":"https://github.com/nest/nest-simulator/pull/17.patch"},"body":"\r\nThese changes include the first step in order to enable structural plasticity in NEST. The implementation corresponds to the formalism described in: M. Butz and A. van Ooyen. A simple rule for dendritic spine and axonal bouton formation can account for cortical reorganization after focal retinal lesions. PLoS Comput. Biol., 9(10):e1003259, Oct 2013.\r\n\r\nThis Model of Structural Plasticity (MSP) considers synapses to be not just a weighted link between two neurons but as consisting of two connected parts, a presynaptic axonal element and a postsynaptic dendritic element. Matching synaptic elements develop independently from each other, only depending on the level of activity of the hosting neuron.\r\nOnce new synaptic elements are formed, they are first considered as vacant. From that moment on, they can be connected with a matching counterpart to form a new synapse in a random process.\r\nSynapses can break apart when a bound synaptic element is deleted. The remaining and now freed synaptic element of the broken synapse can then rebind with a different synaptic element.\r\nBreaking of synapses and rebinding of synaptic elements causes the rewiring of the network until a homoeostatic point is reached.\r\n\r\nThis first request includes only the implementation of classes and data structures to represent synaptic elements and their dynamics within the network. No changes in the connectivity are present at this point."},"comment":{"url":"https://api.github.com/repos/nest/nest-simulator/issues/comments/106838907","html_url":"https://github.com/nest/nest-simulator/pull/17#issuecomment-106838907","issue_url":"https://api.github.com/repos/nest/nest-simulator/issues/17","id":106838907,"user":{"login":"apeyser","id":96407,"avatar_url":"https://avatars.githubusercontent.com/u/96407?v=3","gravatar_id":"","url":"https://api.github.com/users/apeyser","html_url":"https://github.com/apeyser","followers_url":"https://api.github.com/users/apeyser/followers","following_url":"https://api.github.com/users/apeyser/following{/other_user}","gists_url":"https://api.github.com/users/apeyser/gists{/gist_id}","starred_url":"https://api.github.com/users/apeyser/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/apeyser/subscriptions","organizations_url":"https://api.github.com/users/apeyser/orgs","repos_url":"https://api.github.com/users/apeyser/repos","events_url":"https://api.github.com/users/apeyser/events{/privacy}","received_events_url":"https://api.github.com/users/apeyser/received_events","type":"User","site_admin":false},"created_at":"2015-05-29T14:57:22Z","updated_at":"2015-05-29T14:57:22Z","body":"@sdiazpier: I believe that's all the comments I have here, it's mostly lint and questions."}}