{"action":"opened","issue":{"url":"https://api.github.com/repos/firasm/CEST/issues/39","labels_url":"https://api.github.com/repos/firasm/CEST/issues/39/labels{/name}","comments_url":"https://api.github.com/repos/firasm/CEST/issues/39/comments","events_url":"https://api.github.com/repos/firasm/CEST/issues/39/events","html_url":"https://github.com/firasm/CEST/issues/39","id":84322983,"number":39,"title":"CEST Spectrum from Andrew's Brain scan on May 29th","user":{"login":"firasm","id":2507459,"avatar_url":"https://avatars.githubusercontent.com/u/2507459?v=3","gravatar_id":"","url":"https://api.github.com/users/firasm","html_url":"https://github.com/firasm","followers_url":"https://api.github.com/users/firasm/followers","following_url":"https://api.github.com/users/firasm/following{/other_user}","gists_url":"https://api.github.com/users/firasm/gists{/gist_id}","starred_url":"https://api.github.com/users/firasm/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/firasm/subscriptions","organizations_url":"https://api.github.com/users/firasm/orgs","repos_url":"https://api.github.com/users/firasm/repos","events_url":"https://api.github.com/users/firasm/events{/privacy}","received_events_url":"https://api.github.com/users/firasm/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":{"login":"andrewcyung","id":1995950,"avatar_url":"https://avatars.githubusercontent.com/u/1995950?v=3","gravatar_id":"","url":"https://api.github.com/users/andrewcyung","html_url":"https://github.com/andrewcyung","followers_url":"https://api.github.com/users/andrewcyung/followers","following_url":"https://api.github.com/users/andrewcyung/following{/other_user}","gists_url":"https://api.github.com/users/andrewcyung/gists{/gist_id}","starred_url":"https://api.github.com/users/andrewcyung/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/andrewcyung/subscriptions","organizations_url":"https://api.github.com/users/andrewcyung/orgs","repos_url":"https://api.github.com/users/andrewcyung/repos","events_url":"https://api.github.com/users/andrewcyung/events{/privacy}","received_events_url":"https://api.github.com/users/andrewcyung/received_events","type":"User","site_admin":false},"milestone":null,"comments":0,"created_at":"2015-06-03T02:47:07Z","updated_at":"2015-06-03T02:47:07Z","closed_at":null,"body":"@andrewcyung  did a CEST brain scan of a mouse before coming so I thought I'd try and visualize it so we can make sense of it\r\n\r\nThese data are normalized to the 300 ppm freq. offset so they should be comparable to each other.\r\n\r\nHere are andrew's notes on the experiment:\r\n\r\n```Objectives\r\nrepeat successful mouse brain CEST experiment where I got amide/amine peaks\r\nduplicate successful experiment with turboCEST sequence method\r\ninvestigate the effect of acceleration factor, with respect to total saturation time over the course of an entire image acquisition for one particular offset\r\n\r\n** Data Key **\r\n2,3,4: RARE localizers\r\n5,6: fieldmap and shim voxel\r\n9. quick 3-offset CEST scan to characterize B0 homogeneity\r\n10. reproduce successful experiment with ubcCEST_FLASH (1.0 uT, 72x72, 3.6cm FOV, 490 ms sat pulse, TR=500 ms (i.e. ~10 ms imaging time), -1 to 5 ppm with 0.4 ppm stepsize,\r\n11. try to reproduce same thing but with turboCEST acceleration factor 1 (this time, TR has new meaning; does not include sat pulse.  So TR=10ms)\r\n12. same turboCEST sequence but now with 8 sec of inter-experiment delay (between  frequency offset images)\r\n13. now try #12 but with acceleration factor 2\r\n15. acceleration factor of 1, but saturation pulse length is cut in half.   Therefore, time is same as #13 (accel factor 2) and will be about the same saturation duration from start of scan to centre of k-space\r\n16. same as #15 but sat pulse length is 350 ms (narrow range)\r\n17. same as 15 but reverse encoding so that centre of k-space is acquired last\r\n18. repeat of 12 but with narrower frequency range\r\n19. repeat of 18 but accel = 2\r\n20. repeat of 18 but accel = 4\r\n21. repeat of 18 but accel = 8\r\n22. repeat of 12 but narrower frequency range\r\n```\r\n\r\nFor 1 pixel (blue star)\r\n\r\n![unknown](https://cloud.githubusercontent.com/assets/2507459/7951725/247439e2-0979-11e5-9eb1-f578182c5c0e.png)\r\n\r\n![unknown-1](https://cloud.githubusercontent.com/assets/2507459/7951734/2e2e512a-0979-11e5-80b3-4e1ee92d562e.png)\r\n"}}