{"action":"created","issue":{"url":"https://api.github.com/repos/stephens999/gtex-viz/issues/6","labels_url":"https://api.github.com/repos/stephens999/gtex-viz/issues/6/labels{/name}","comments_url":"https://api.github.com/repos/stephens999/gtex-viz/issues/6/comments","events_url":"https://api.github.com/repos/stephens999/gtex-viz/issues/6/events","html_url":"https://github.com/stephens999/gtex-viz/issues/6","id":85175765,"number":6,"title":"expression: patterns of expression across tissues","user":{"login":"stephens999","id":1800389,"avatar_url":"https://avatars.githubusercontent.com/u/1800389?v=3","gravatar_id":"","url":"https://api.github.com/users/stephens999","html_url":"https://github.com/stephens999","followers_url":"https://api.github.com/users/stephens999/followers","following_url":"https://api.github.com/users/stephens999/following{/other_user}","gists_url":"https://api.github.com/users/stephens999/gists{/gist_id}","starred_url":"https://api.github.com/users/stephens999/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/stephens999/subscriptions","organizations_url":"https://api.github.com/users/stephens999/orgs","repos_url":"https://api.github.com/users/stephens999/repos","events_url":"https://api.github.com/users/stephens999/events{/privacy}","received_events_url":"https://api.github.com/users/stephens999/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":5,"created_at":"2015-06-04T16:37:51Z","updated_at":"2015-06-20T17:32:07Z","closed_at":null,"body":"Here the idea is to do analogues of the previous issues, but based on raw expression, not eQTLs.\r\nKushal has already done a bunch of this  - eg the structure analysis and clustering of tissues\r\nhe presented at last gtex meeting. It just needs putting in one place here.\r\n\r\n- heatmap showing pairwise similarity of tissues in terms of expression. \r\n- tsne clustering of tissues showing similar patterns of expression.\r\n- structure analysis, clustering tissues. (tsne clustering of structure results?)\r\n- sfa of expression data? \r\n\r\n"},"comment":{"url":"https://api.github.com/repos/stephens999/gtex-viz/issues/comments/113792456","html_url":"https://github.com/stephens999/gtex-viz/issues/6#issuecomment-113792456","issue_url":"https://api.github.com/repos/stephens999/gtex-viz/issues/6","id":113792456,"user":{"login":"kkdey","id":9523596,"avatar_url":"https://avatars.githubusercontent.com/u/9523596?v=3","gravatar_id":"","url":"https://api.github.com/users/kkdey","html_url":"https://github.com/kkdey","followers_url":"https://api.github.com/users/kkdey/followers","following_url":"https://api.github.com/users/kkdey/following{/other_user}","gists_url":"https://api.github.com/users/kkdey/gists{/gist_id}","starred_url":"https://api.github.com/users/kkdey/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/kkdey/subscriptions","organizations_url":"https://api.github.com/users/kkdey/orgs","repos_url":"https://api.github.com/users/kkdey/repos","events_url":"https://api.github.com/users/kkdey/events{/privacy}","received_events_url":"https://api.github.com/users/kkdey/received_events","type":"User","site_admin":false},"created_at":"2015-06-20T17:32:07Z","updated_at":"2015-06-20T17:32:07Z","body":"I now have a scatter plot for a gene (the most highly expressed gene) for Brain Amygdala and Brain Hypothalamus : https://github.com/stephens999/gtex-viz/blob/master/gtex.Kushal/plots/brain_scatter_plot.pdf\r\n\r\nAlso for the same gene between Skin exposed and not exposed : https://github.com/stephens999/gtex-viz/blob/master/gtex.Kushal/plots/skin_scatter_plot.pdf\r\n\r\nAnd a heatmap of the proportion of cases having correlation more than 0.3 across tissues (brain tissues clearly show higher proportion) : https://github.com/stephens999/gtex-viz/blob/master/gtex.Kushal/plots/cor_thresh_0_3.pdf"}}