{"action":"created","issue":{"url":"https://api.github.com/repos/genome/dgi-db/issues/49","labels_url":"https://api.github.com/repos/genome/dgi-db/issues/49/labels{/name}","comments_url":"https://api.github.com/repos/genome/dgi-db/issues/49/comments","events_url":"https://api.github.com/repos/genome/dgi-db/issues/49/events","html_url":"https://github.com/genome/dgi-db/issues/49","id":104083427,"number":49,"title":"Drug-gene interactions from CIVIC for query list of drugs report gene ID instead of symbol","user":{"login":"malachig","id":856728,"avatar_url":"https://avatars.githubusercontent.com/u/856728?v=3","gravatar_id":"","url":"https://api.github.com/users/malachig","html_url":"https://github.com/malachig","followers_url":"https://api.github.com/users/malachig/followers","following_url":"https://api.github.com/users/malachig/following{/other_user}","gists_url":"https://api.github.com/users/malachig/gists{/gist_id}","starred_url":"https://api.github.com/users/malachig/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/malachig/subscriptions","organizations_url":"https://api.github.com/users/malachig/orgs","repos_url":"https://api.github.com/users/malachig/repos","events_url":"https://api.github.com/users/malachig/events{/privacy}","received_events_url":"https://api.github.com/users/malachig/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":4,"created_at":"2015-08-31T16:13:31Z","updated_at":"2015-08-31T16:41:14Z","closed_at":null,"body":"On the live site.\r\n\r\nI searched for ERLOTINIB, IBRUTINIB, and LAPATINIB.\r\n\r\nFor CIViC results and and various other sources as well, the \"Gene\" shown is the Entrez ID instead of the Entrez gene symbol.  Even if Entrez ID was available shouldn't these have been imported with the Gene Symbol as their gene record?\r\n\r\nFor example I get an 'ERLOTINIB' and '19' drug-gene interaction.  19 is EGFR.\r\n\r\nI also see appear to be duplicate interactions from CIViC.  For example,\r\nhttp://dgidb.genome.wustl.edu/interaction_claims/bd41a7e7-4ac6-45bd-9f0f-71e2daedfad5\r\nhttp://dgidb.genome.wustl.edu/interaction_claims/9e2984b9-d532-476b-b1f2-f4c6b8bc5bdc\r\n\r\nWhen I query from the gene direction and enter 'EGFR' I get a gene-drug interaction with 'ERLOTINIB'. So that looks nicer though I see all the same duplicate entries there as well of course.\r\n\r\n![screen shot 2015-08-31 at 11 13 21 am](https://cloud.githubusercontent.com/assets/856728/9583497/4e755732-4fd1-11e5-8f32-8b3cdf9df621.png)\r\n"},"comment":{"url":"https://api.github.com/repos/genome/dgi-db/issues/comments/136424363","html_url":"https://github.com/genome/dgi-db/issues/49#issuecomment-136424363","issue_url":"https://api.github.com/repos/genome/dgi-db/issues/49","id":136424363,"user":{"login":"ahwagner","id":811065,"avatar_url":"https://avatars.githubusercontent.com/u/811065?v=3","gravatar_id":"","url":"https://api.github.com/users/ahwagner","html_url":"https://github.com/ahwagner","followers_url":"https://api.github.com/users/ahwagner/followers","following_url":"https://api.github.com/users/ahwagner/following{/other_user}","gists_url":"https://api.github.com/users/ahwagner/gists{/gist_id}","starred_url":"https://api.github.com/users/ahwagner/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ahwagner/subscriptions","organizations_url":"https://api.github.com/users/ahwagner/orgs","repos_url":"https://api.github.com/users/ahwagner/repos","events_url":"https://api.github.com/users/ahwagner/events{/privacy}","received_events_url":"https://api.github.com/users/ahwagner/received_events","type":"User","site_admin":false},"created_at":"2015-08-31T16:41:14Z","updated_at":"2015-08-31T16:41:14Z","body":"Ah. We can definitely make that change for the CIViC importer, then. We will also need to update CIViC to accept gene symbol lookups in the URL. To illustrate what I mean:\r\n\r\nhttps://civic.genome.wustl.edu/#/events/genes/42 will work fine.\r\nhttps://civic.genome.wustl.edu/#/events/genes/RET hangs.\r\n\r\nGTP is the same way (although we obviously have less control over this):\r\n\r\nhttp://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1797 will work.\r\nhttp://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=EGFR will not.\r\n\r\nThis may be an issue with the way we do linking now, though. I like the idea of keeping the primary record IDs consistent."}}