{"action":"created","issue":{"url":"https://api.github.com/repos/sys-bio/roadrunner/issues/114","labels_url":"https://api.github.com/repos/sys-bio/roadrunner/issues/114/labels{/name}","comments_url":"https://api.github.com/repos/sys-bio/roadrunner/issues/114/comments","events_url":"https://api.github.com/repos/sys-bio/roadrunner/issues/114/events","html_url":"https://github.com/sys-bio/roadrunner/issues/114","id":67034401,"number":114,"title":"RoadRunner crashes with Biomodels 9","user":{"login":"hsauro","id":1054990,"avatar_url":"https://avatars.githubusercontent.com/u/1054990?v=3","gravatar_id":"","url":"https://api.github.com/users/hsauro","html_url":"https://github.com/hsauro","followers_url":"https://api.github.com/users/hsauro/followers","following_url":"https://api.github.com/users/hsauro/following{/other_user}","gists_url":"https://api.github.com/users/hsauro/gists{/gist_id}","starred_url":"https://api.github.com/users/hsauro/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/hsauro/subscriptions","organizations_url":"https://api.github.com/users/hsauro/orgs","repos_url":"https://api.github.com/users/hsauro/repos","events_url":"https://api.github.com/users/hsauro/events{/privacy}","received_events_url":"https://api.github.com/users/hsauro/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/sys-bio/roadrunner/labels/bug","name":"bug","color":"fc2929"},{"url":"https://api.github.com/repos/sys-bio/roadrunner/labels/priority","name":"priority","color":"eb6420"}],"state":"open","locked":false,"assignee":{"login":"0u812","id":7402146,"avatar_url":"https://avatars.githubusercontent.com/u/7402146?v=3","gravatar_id":"","url":"https://api.github.com/users/0u812","html_url":"https://github.com/0u812","followers_url":"https://api.github.com/users/0u812/followers","following_url":"https://api.github.com/users/0u812/following{/other_user}","gists_url":"https://api.github.com/users/0u812/gists{/gist_id}","starred_url":"https://api.github.com/users/0u812/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/0u812/subscriptions","organizations_url":"https://api.github.com/users/0u812/orgs","repos_url":"https://api.github.com/users/0u812/repos","events_url":"https://api.github.com/users/0u812/events{/privacy}","received_events_url":"https://api.github.com/users/0u812/received_events","type":"User","site_admin":false},"milestone":null,"comments":7,"created_at":"2015-04-08T02:37:32Z","updated_at":"2015-08-27T23:48:33Z","closed_at":null,"body":"It has been reported that CVODE in libRoadRunner crashes with Biomodels 09. Contact Kyle for details."},"comment":{"url":"https://api.github.com/repos/sys-bio/roadrunner/issues/comments/135585963","html_url":"https://github.com/sys-bio/roadrunner/issues/114#issuecomment-135585963","issue_url":"https://api.github.com/repos/sys-bio/roadrunner/issues/114","id":135585963,"user":{"login":"0u812","id":7402146,"avatar_url":"https://avatars.githubusercontent.com/u/7402146?v=3","gravatar_id":"","url":"https://api.github.com/users/0u812","html_url":"https://github.com/0u812","followers_url":"https://api.github.com/users/0u812/followers","following_url":"https://api.github.com/users/0u812/following{/other_user}","gists_url":"https://api.github.com/users/0u812/gists{/gist_id}","starred_url":"https://api.github.com/users/0u812/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/0u812/subscriptions","organizations_url":"https://api.github.com/users/0u812/orgs","repos_url":"https://api.github.com/users/0u812/repos","events_url":"https://api.github.com/users/0u812/events{/privacy}","received_events_url":"https://api.github.com/users/0u812/received_events","type":"User","site_admin":false},"created_at":"2015-08-27T23:48:33Z","updated_at":"2015-08-27T23:48:33Z","body":"I can get this to simulate using extremely small tolerances. Not sure why Jarnac can do it with looser tols, maybe it uses a stiff solver.\r\n\r\n1e-14 (rel & abs):\r\n![](https://raw.githubusercontent.com/wiki/sys-bio/roadrunner/img/biomod9/cvode-1e-14.png)\r\n\r\n1e-13:\r\n![](https://raw.githubusercontent.com/wiki/sys-bio/roadrunner/img/biomod9/cvode-1e-13.png)\r\n\r\n5e-13:\r\n![](https://raw.githubusercontent.com/wiki/sys-bio/roadrunner/img/biomod9/cvode-5e-13.png)"}}