{"action":"opened","issue":{"url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/346","labels_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/346/labels{/name}","comments_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/346/comments","events_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/346/events","html_url":"https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/346","id":84769715,"number":346,"title":"promoter motif 8","user":{"login":"srynobio","id":1106139,"avatar_url":"https://avatars.githubusercontent.com/u/1106139?v=3","gravatar_id":"","url":"https://api.github.com/users/srynobio","html_url":"https://github.com/srynobio","followers_url":"https://api.github.com/users/srynobio/followers","following_url":"https://api.github.com/users/srynobio/following{/other_user}","gists_url":"https://api.github.com/users/srynobio/gists{/gist_id}","starred_url":"https://api.github.com/users/srynobio/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/srynobio/subscriptions","organizations_url":"https://api.github.com/users/srynobio/orgs","repos_url":"https://api.github.com/users/srynobio/repos","events_url":"https://api.github.com/users/srynobio/events{/privacy}","received_events_url":"https://api.github.com/users/srynobio/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":0,"created_at":"2015-06-03T21:00:30Z","updated_at":"2015-06-03T21:00:30Z","closed_at":null,"body":"**Reported by nlw on 2007-09-11 19:13 UTC**\nName:  Motif 8\r\n\r\nDef: \r\nA sequence element characteristic of some RNA polymerase II promoters, usually located between -60 and -45 relative to the TSS. Consensus sequence is MKSYGGCARCGSYSS. Tends to co-occur with motif 7.  Tends to not occur with DPE motif \\(SO:0000015\\) or motif 10.\r\n\r\nDBxref: PMID:12537576\r\n\r\nComment:\r\nThis consensus sequence was identified computationally using the MEME algorithm within core promoter sequences from -60 to +40, with an E value of 5.1e-29."}}