{"action":"closed","issue":{"url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/73","labels_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/73/labels{/name}","comments_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/73/comments","events_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/73/events","html_url":"https://github.com/BgeeDB/expression-annotations/issues/73","id":114547098,"number":73,"title":"tricky GTEx colon mucosa annotation","user":{"login":"ANiknejad","id":2682520,"avatar_url":"https://avatars.githubusercontent.com/u/2682520?v=3","gravatar_id":"","url":"https://api.github.com/users/ANiknejad","html_url":"https://github.com/ANiknejad","followers_url":"https://api.github.com/users/ANiknejad/followers","following_url":"https://api.github.com/users/ANiknejad/following{/other_user}","gists_url":"https://api.github.com/users/ANiknejad/gists{/gist_id}","starred_url":"https://api.github.com/users/ANiknejad/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ANiknejad/subscriptions","organizations_url":"https://api.github.com/users/ANiknejad/orgs","repos_url":"https://api.github.com/users/ANiknejad/repos","events_url":"https://api.github.com/users/ANiknejad/events{/privacy}","received_events_url":"https://api.github.com/users/ANiknejad/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/BgeeDB/expression-annotations/labels/GTEx","name":"GTEx","color":"fad8c7"}],"state":"closed","locked":false,"assignee":null,"milestone":null,"comments":3,"created_at":"2015-11-02T08:25:16Z","updated_at":"2015-12-21T10:28:31Z","closed_at":"2015-12-21T10:28:31Z","body":"This is not clear which colon 'muscularis' is the target: muscularis mucosa OR muscularis propria\r\nLook at \r\nhttp://www.histology.leeds.ac.uk/digestive/GI_layers.php\r\n\r\n1271796\tGTEX-WH7G-1426-SM-4LVMU\r\n\r\n'6 pieces, up to 10x4mm; All have muscularis propria (our target) but 5 of 6 have (unwanted) mucosa'\r\n-> this is mapped on 1159\tsigmoid colon\r\nIf this is realy 'muscularis propria', should be mapped on new Uberon term \r\nid: UBERON:0035805\r\n+name: muscle layer of sigmoid colon\r\n\r\nBut others guys talk about only 'muscularis'\r\n1267692\tGTEX-11EQ9-1526-SM-5PNY7\r\n6 pieces, muscularis, adherent rim of serosa/fat up to ~1.5mm\r\n\r\n--> and this is also mapped on 1159\tsigmoid colon\r\n\r\n1267342\tGTEX-111YS-1826-SM-5GIEP\r\n6 pieces; muscularis (target) with up to 1 mm external fat\r\n--> and this is also mapped on 1159\tsigmoid colon\r\n\r\nFor esophagus, the target sounds to be 'muscularis mucosa':\r\n\r\n1268726\tGTEX-12WSL-1526-SM-5GCP8\r\n5 pieces; well dissected mucosa with prominent muscularis mucosae\r\nmapped on 6920\tesophagus squamous epithelium\r\n\r\n\r\n"}}