{"action":"opened","issue":{"url":"https://api.github.com/repos/johnlees/seer/issues/16","labels_url":"https://api.github.com/repos/johnlees/seer/issues/16/labels{/name}","comments_url":"https://api.github.com/repos/johnlees/seer/issues/16/comments","events_url":"https://api.github.com/repos/johnlees/seer/issues/16/events","html_url":"https://github.com/johnlees/seer/issues/16","id":119496215,"number":16,"title":"Speed up firth regression","user":{"login":"johnlees","id":6331837,"avatar_url":"https://avatars.githubusercontent.com/u/6331837?v=3","gravatar_id":"","url":"https://api.github.com/users/johnlees","html_url":"https://github.com/johnlees","followers_url":"https://api.github.com/users/johnlees/followers","following_url":"https://api.github.com/users/johnlees/following{/other_user}","gists_url":"https://api.github.com/users/johnlees/gists{/gist_id}","starred_url":"https://api.github.com/users/johnlees/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/johnlees/subscriptions","organizations_url":"https://api.github.com/users/johnlees/orgs","repos_url":"https://api.github.com/users/johnlees/repos","events_url":"https://api.github.com/users/johnlees/events{/privacy}","received_events_url":"https://api.github.com/users/johnlees/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/johnlees/seer/labels/enhancement","name":"enhancement","color":"84b6eb"},{"url":"https://api.github.com/repos/johnlees/seer/labels/low%20priority","name":"low priority","color":"f7c6c7"},{"url":"https://api.github.com/repos/johnlees/seer/labels/stats","name":"stats","color":"fbca04"}],"state":"open","locked":false,"assignee":{"login":"johnlees","id":6331837,"avatar_url":"https://avatars.githubusercontent.com/u/6331837?v=3","gravatar_id":"","url":"https://api.github.com/users/johnlees","html_url":"https://github.com/johnlees","followers_url":"https://api.github.com/users/johnlees/followers","following_url":"https://api.github.com/users/johnlees/following{/other_user}","gists_url":"https://api.github.com/users/johnlees/gists{/gist_id}","starred_url":"https://api.github.com/users/johnlees/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/johnlees/subscriptions","organizations_url":"https://api.github.com/users/johnlees/orgs","repos_url":"https://api.github.com/users/johnlees/repos","events_url":"https://api.github.com/users/johnlees/events{/privacy}","received_events_url":"https://api.github.com/users/johnlees/received_events","type":"User","site_admin":false},"milestone":null,"comments":0,"created_at":"2015-11-30T13:53:58Z","updated_at":"2015-11-30T13:53:58Z","closed_at":null,"body":"Try using BOBYQA algorithm to maximise likelihood for Firth regression, rather than N-R iterations. I wonder if it might be faster..."}}