{"action":"created","issue":{"url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/58","labels_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/58/labels{/name}","comments_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/58/comments","events_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/58/events","html_url":"https://github.com/BgeeDB/expression-annotations/issues/58","id":110145831,"number":58,"title":"GTEx normality - individual cases","user":{"login":"aechchiki","id":13200013,"avatar_url":"https://avatars.githubusercontent.com/u/13200013?v=3","gravatar_id":"","url":"https://api.github.com/users/aechchiki","html_url":"https://github.com/aechchiki","followers_url":"https://api.github.com/users/aechchiki/followers","following_url":"https://api.github.com/users/aechchiki/following{/other_user}","gists_url":"https://api.github.com/users/aechchiki/gists{/gist_id}","starred_url":"https://api.github.com/users/aechchiki/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/aechchiki/subscriptions","organizations_url":"https://api.github.com/users/aechchiki/orgs","repos_url":"https://api.github.com/users/aechchiki/repos","events_url":"https://api.github.com/users/aechchiki/events{/privacy}","received_events_url":"https://api.github.com/users/aechchiki/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/BgeeDB/expression-annotations/labels/GTEx","name":"GTEx","color":"fad8c7"}],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":1,"created_at":"2015-10-07T03:26:06Z","updated_at":"2015-10-07T13:40:20Z","closed_at":null,"body":"Some other funny subject cases that came in (following new normality rules #55 and #54):\r\n\r\n- what if subjects were reported to be cocaine users (5y before death)? \r\n>>> example: ID 590922 (died from Cerebral Vascular Accident, and suffered from dementia and schizophrenia): i would have discarded only brain tissue.... but  this is a case of drug use.... how to proceed?\r\n- what if subjects were reported to abuse from prescription pills, but the cause of death is not directly linked to drug abuse (example: ID 590955, formally died by motor vehicle accident)\r\n- what if the subjects were diagnosed with \"non-metastatic cancer\" (they don't say where/what type of cancer),  but the cause of death is not directly linked to cancer (example: ID 590934, formally died because of pontine bleed )\r\n- what about subjects suffering from arthritis? it's not specified whether it's rheumatoid or not; thus in the most optimistic case it would only design \"articulation inflammation\"... how to proceed?\r\n- there are LOADS of subjects suffering from diabetes (type II)... isn't it too restrictive to discard them all?\r\n- what about subjects who have been reported \"positive for blood cultures\", aka bacteria were found in blood samples? same for subjects  who have been reported \"septic\", aka bacteria or toxins were found in body fluids. I think that we should discard them, because it could be the sign of a systemic infection\r\n"},"comment":{"url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/comments/146199069","html_url":"https://github.com/BgeeDB/expression-annotations/issues/58#issuecomment-146199069","issue_url":"https://api.github.com/repos/BgeeDB/expression-annotations/issues/58","id":146199069,"user":{"login":"mimiblis","id":13200045,"avatar_url":"https://avatars.githubusercontent.com/u/13200045?v=3","gravatar_id":"","url":"https://api.github.com/users/mimiblis","html_url":"https://github.com/mimiblis","followers_url":"https://api.github.com/users/mimiblis/followers","following_url":"https://api.github.com/users/mimiblis/following{/other_user}","gists_url":"https://api.github.com/users/mimiblis/gists{/gist_id}","starred_url":"https://api.github.com/users/mimiblis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/mimiblis/subscriptions","organizations_url":"https://api.github.com/users/mimiblis/orgs","repos_url":"https://api.github.com/users/mimiblis/repos","events_url":"https://api.github.com/users/mimiblis/events{/privacy}","received_events_url":"https://api.github.com/users/mimiblis/received_events","type":"User","site_admin":false},"created_at":"2015-10-07T13:40:20Z","updated_at":"2015-10-07T13:40:20Z","body":"@aechchiki : as discussed by whatsapp ;-P\r\n(when I put something here, it means all other param have been checked and are ok, that is why I hesitate)\r\n- GTEX-145MO: what do you think of 'unspecified heart disease' (hardy 3), I would throw it away...\r\n- GTEX-1445S: they say 'heart attack', then heart disease, with an underlying cause of GastroIntestinal bleeding (hardy 3) --> ?\r\n- GTEX-13RTJ: resp. failure, with underlying cause = dehydration --> for me keep all?\r\n- GTEX-13O3P: resp. failure due to GI bleeding --> ?\r\n- GTEX-14E6E: je me souviens plus, head trauma on garde aussi le cerveau?\r\n- GTEX-13FHO: end stage liver disease, mais avec DHHRDY de 0?"}}