{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/synapse/issues/22","labels_url":"https://api.github.com/repos/geneontology/synapse/issues/22/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/synapse/issues/22/comments","events_url":"https://api.github.com/repos/geneontology/synapse/issues/22/events","html_url":"https://github.com/geneontology/synapse/issues/22","id":98156326,"number":22,"title":"Defining ion channel/transporter properties","user":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"milestone":{"url":"https://api.github.com/repos/geneontology/synapse/milestones/3","html_url":"https://github.com/geneontology/synapse/milestones/synaptic%20transmission%20terms%20fit%20for%20annotation","labels_url":"https://api.github.com/repos/geneontology/synapse/milestones/3/labels","id":1151090,"number":3,"title":"synaptic transmission terms fit for annotation","description":"Date by which synaptic transmission terms & their context in the ontology should be of a quality sufficient for annotation to start.","creator":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"open_issues":5,"closed_issues":0,"state":"open","created_at":"2015-06-05T12:53:13Z","updated_at":"2015-07-30T12:16:19Z","due_on":"2015-08-30T23:00:00Z","closed_at":null},"comments":4,"created_at":"2015-07-30T12:16:19Z","updated_at":"2015-07-30T12:51:27Z","closed_at":null,"body":"During discussion of how to record the function of gene products in the PSP/PSC and its regulation, we agreed that we need a good set of molecular function terms covering ion channels and pumps acting at the post-synaptic membrane.  GO already has quite good coverage of these functions, but we should review definitions for key properties:\r\n\r\n**channels**\r\n- gating\r\n  - ligand\r\n  - second messenger\r\n  - voltage\r\n  - ion\r\n  - mechanical (probably not relevant to this project?)\r\n- Cargo/selectivity\r\n- Rectifier\r\n  - inward\r\n  - outward\r\n  - delayed\r\n  - open\r\n\r\n**transmembrane ion transporters**"},"comment":{"url":"https://api.github.com/repos/geneontology/synapse/issues/comments/126312456","html_url":"https://github.com/geneontology/synapse/issues/22#issuecomment-126312456","issue_url":"https://api.github.com/repos/geneontology/synapse/issues/22","id":126312456,"user":{"login":"bmeldal","id":10517124,"avatar_url":"https://avatars.githubusercontent.com/u/10517124?v=3","gravatar_id":"","url":"https://api.github.com/users/bmeldal","html_url":"https://github.com/bmeldal","followers_url":"https://api.github.com/users/bmeldal/followers","following_url":"https://api.github.com/users/bmeldal/following{/other_user}","gists_url":"https://api.github.com/users/bmeldal/gists{/gist_id}","starred_url":"https://api.github.com/users/bmeldal/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/bmeldal/subscriptions","organizations_url":"https://api.github.com/users/bmeldal/orgs","repos_url":"https://api.github.com/users/bmeldal/repos","events_url":"https://api.github.com/users/bmeldal/events{/privacy}","received_events_url":"https://api.github.com/users/bmeldal/received_events","type":"User","site_admin":false},"created_at":"2015-07-30T12:51:27Z","updated_at":"2015-07-30T12:51:27Z","body":"related tickets:\r\nhttps://github.com/geneontology/go-ontology/issues/11989 (Kir6.x channels)\r\nhttps://github.com/geneontology/go-ontology/issues/11978 (acetylcholine receptor activity)\r\n"}}