$401$ is around $400$ and $.205$ is around $.2$ so the [fraction](https://artofproblemsolving.com/wiki/index.php/Fraction) is approximately \[\frac{400}{.2}=2000\rightarrow \boxed{\text{E}}\]
Estimate to determine which of the following numbers is closest to $\frac{401}{.205}$.
$\text{(A)}\ .2 \qquad \text{(B)}\ 2 \qquad \text{(C)}\ 20 \qquad \text{(D)}\ 200 \qquad \text{(E)}\ 2000$