We can solve this problem with a brute force approach.

If Cal's number is $1$:
If Bill's number is $2$, Al's can be any of $4, 6, 8, 10$.
If Bill's number is $3$, Al's can be any of $6, 9$.
If Bill's number is $4$, Al's can be $8$.
If Bill's number is $5$, Al's can be $10$.
Otherwise, Al's number could not be a whole number multiple of Bill's.
If Cal's number is $2$:
If Bill's number is $4$, Al's can be $8$.
Otherwise, Al's number could not be a whole number multiple of Bill's while Bill's number is still a whole number multiple of Cal's.
Otherwise, Bill's number must be greater than $5$, i.e. Al's number could not be a whole number multiple of Bill's.
Clearly, there are exactly $9$ cases where Al's number will be a whole number multiple of Bill's and Bill's number will be a whole number multiple of Cal's. Since there are $10*9*8$ possible permutations of the numbers Al, Bill, and Cal were assigned, the probability that this is true is $\frac9{10*9*8}=\boxed{\text{(\textbf C) }\frac1{80}}$
Al, Bill, and Cal will each randomly be assigned a whole number from $1$ to $10$, inclusive, with no two of them getting the same number. What is the probability that Al's number will be a whole number multiple of Bill's and Bill's number will be a whole number multiple of Cal's?
$\textbf{(A) } \dfrac{9}{1000} \qquad\textbf{(B) } \dfrac{1}{90} \qquad\textbf{(C) } \dfrac{1}{80} \qquad\textbf{(D) } \dfrac{1}{72} \qquad\textbf{(E) } \dfrac{2}{121}$