1 colonization of a niche in the host (this includes attachment to cells). 2 immunoevasion, evasion of the host's immune response.
Virulence factors are molecules produced by pathogens (bacteria, viruses, fungi and protozoa) that contribute to the pathogenicity of the organism and enable them to achieve the following: 1  colonization of a niche in the host (this includes attachment to cells). 2  immunoevasion, evasion of the host's immune response. Bacterial virulence factors enable a host to replicate and disseminate within a host in part by subverting or eluding host defenses. The use of genomic techniques has led to the identification of new virulence factors that may serve as targets for new therapies. 1 Bacterial Virulence Factors are molecules synthesized by certain bacteria that increases their capacity to infect or damage human tissues. 1 Invasion Factors. 2  Some virulent bacteria produce proteins that either disrupt host cell membranes or stimulate endocytosis into host cells. 3  These virulence factors allow the bacteria to enter host cells and facilitate entry into the body across epithelial tissue layers at the body surface. * obtain nutrition from the host. Virulence factors are very often responsible for causing disease in the host as they inhibit certain host functions. Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to adhere to cells. In essence, the ability of pathogenic bacteria to cause disease in a susceptible host is determined by multiple virulence factors acting individually or together at different stages of infection. Discovering virulence factors of pathogenic bacteria is a key in understanding pathogenesis and for identification of targets for novel drugs and design of new vaccines. Virulence factors are molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following: * colonization of a niche in the host (this includes adhesion to cells). * Immunoevasion, evasion of the host's immune response.
https://en.wikipedia.org/wiki/Virulence_factor http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646308/ http://pathwaymedicine.org/bacterial-virulence-factors http://www2.cedarcrest.edu/academic/bio/hale/bioT_EID/lectures/anthraxvirulence.html http://www.bioportfolio.com/channels/virulence-factors http://www.sciencedirect.com/science/article/pii/S1367593108000148 http://www.sciencedirect.com/science/article/pii/S1367593108000148 http://www.bioportfolio.com/channels/virulence-factors
what are bacterial virulence factors