The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.
1 an outer kinetochore, which interacts with microtubules; the outer kinetochore is a very dynamic structure, with many identical components, which are assembled and functional only during cell division. The kinetochore forms in eukaryotes, assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis and meiosis. Making the world better, one answer at a time. As the centrosomes separate, spindle fibers made of microtubules radiate from the centrosome in preparation for mitosis. This array of spindle fibers is called the mitotic spindle, which serves to equally divide the chromatids between the two offspring cells during cell division. Two types of spindle fibers make up the mitotic spindle: kinetochore fibers and polar fibers.  spindle fibers. Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during both types of nuclear division: mitosis and meiosis. During mitosis, the spindle fibers are called the mitotic spindle. Meanwhile, during meiosis, the spindle fibers are referred to as the meiotic spindle '+A+. Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during both types of nuclear division: mitosis and meiosis. During mitosis, the spindle fibers are called the mitotic spindle. Meanwhile, during meiosis, the spindle fibers are referred to as the meiotic spindle Lesson Summary. The mitotic spindle is a structure composed of microtubules which segregates chromosomes into the daughter cells during mitosis. A microtubule is a rope-like component of the cytoskeleton. The centrosome is an organelle that serves as a microtubule organizing center during cell division. An astral microtubule is a short microtubule which emanates from the centrosome and serves to accurately position the mitotic spindle within the cell. A kinetochore microtubule is a microtubule which attaches to the kinetochore and positions the chromosome The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function. In most cell types, spindle microtubule nucleation occurs primarily at two centrosomes, which define the spindle poles, but microtubules can also be generated by the chromosomes and within the spindle itself. The kinetochore /kɪˈnɛtəkɔər/ is the protein structure on chromatids where the spindle fibers attach during cell division to pull sister chromatids apart. The kinetochore forms in eukaryotes, assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis and meiosis. Attachments. Spindle microtubules attach to a specific protein complex called the kinetochore, which is in the centromere area near the center of each chromosome. Other microtubules attach to the chromosome arms or to the other end of the cell. The chromosomes can also create microtubules, as can the spindle itself It is also referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process that produces gametes with half the number of chromosomes of the parent cell. In cell biology, spindle apparatus refers to the subcellular structure of eukaryotic cells that separates chromosomes between daughter cells during cell division.
https://en.wikipedia.org/wiki/Kinetochore http://www.answers.com/Q/What_is_the_structure_and_function_of_the_mitotic_spindle http://www.nature.com/scitable/definition/spindle-fibers-304 http://www.nature.com/scitable/definition/spindle-fibers-304 http://study.com/academy/lesson/mitosis-i-the-mitotic-spindle.html http://www.ncbi.nlm.nih.gov/pubmed/18275887 https://en.wikipedia.org/wiki/Kinetochore http://education.seattlepi.com/function-spindles-perform-during-mitosis-4730.html https://en.wikipedia.org/wiki/Spindle_apparatus
what is the function and structure of a mitotic spindle