Prostaglandins are known as local hormones-they are released from cells and bring about changes in neighbouring cells that carry specific prostaglandin receptors in their membranes. The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.
Release of these enzymes results in production of prostaglandins, with consequent induction of pain. High concentrations of prostaglandins cause pain by direct action upon nerve endings. More typically, however, at low concentrations, they markedly increase sensitivity to pain. The pain threshold may be so altered that even normally painless stimuli may be painful. There are many steps involved in conversion of the fatty acids to prostaglandins. Prostaglandins are not only synthesized when tissues are injured, but are ubiquitous throughout the body. They are not stored but are synthesized upon need. The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from fatty acids. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are a subclass of eicosanoids and form the prostanoid class of fatty acid derivatives. The structural differences between prostaglandins account for their different biological activities. Prostaglandins differ from endocrine hormones in that they are not produced at a specific site but in many places throughout the human body. Prostaglandins have two derivatives: prostacyclins and thromboxanes. Prostaglandins and inflamation. Prostaglandins are known as local hormones-they are released from cells and bring about changes in neighbouring cells that carry specific prostaglandin receptors in their membranes. The influence which prostaglandins have depends upon the type of tissue they are acting upon. Prostaglandins and endometriosis. Prostaglandins and pain messengers. Prostaglandins serve a variety of regulatory functions within the body. One of these functions is to assist the transmission of pain signals to the brain so that you are readily alerted that damage or dysfunction has occurred Functions of Prostaglandins-some basics. They have a variety of physiological effects on the body including: - Activation of the inflammatory responses at the sites of damaged tissue, and production of pain and fever. When tissues are damaged, white blood cells flood the site to try to minimise tissue destruction. These hormones are called prostaglandins and they are found throughout your body. There are two types of prostaglandins in the body – ‘good prostaglandins’ and’ bad prostaglandins’. The bad ones are called Antagonistic Prostaglandins and they cause: 1  Pain. 2  Inflammation. A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are mediators and have a variety of strong physiological effects, such as regulating the contraction and relaxation of smooth muscle tissue. Prostaglandins are not hormones, but autocrine or paracrine, which are locally acting messenger molecules. Also, their target cells are present in the immediate vicinity of the site of their secretion (of which there are many). The prostaglandins, together with the thromboxanes and prostacyclins, form the prostanoid class of fatty acid derivatives, a subclass of eicosanoids. Prostaglandins are a member of the lipid class of biochemicals and are known for their potent physiological properties. They belong to a subclass of lipids known as the eicosanoids because of their structural similarities to the C-20 polyunsaturated fatty acids, the eicosanoic acids.  Print | Email article to a friend | Last updated: October 24, 2013. The prostaglandins are a group of lipids made at sites of tissue damage or infection that are involved in dealing with injury and illness. They control processes such as inflammation, blood flow, the formation of blood clots and the induction of labour. Alternative names for prostaglandins Prostaglandin D2; prostaglandin E2; prostaglandin F2; prostaglandin I2 (which is also known as prostacyclin); a closely related lipid called thromboxane.
http://www.banamine.com/research/Prostaglandins.asp https://en.wikipedia.org/wiki/Prostaglandin http://www.endo-resolved.com/prostaglandins_endometriosis.html http://www.endo-resolved.com/prostaglandins.html http://www.lgmpharma.com/blog/prostaglandins/ http://micro.magnet.fsu.edu/micro/gallery/prostaglandin/prostaglandin.html http://www.yourhormones.info/hormones/prostaglandins.aspx
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