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Calcitonin reduces calcium levels in the blood by two main mechanisms: 1  It inhibits the activity of osteoclasts, which are the cells responsible for breaking down bone. 2  It can also decrease the resorption of calcium in the kidneys, again leading to lower blood calcium levels. The secretion of calcitonin is also inhibited by the hormone somatostatin which is also released by the C-cells in the thyroid gland. What happens if I have too much calcitonin? There does not seem to be any effect on the body as a result of having too much calcitonin. Calcitonin is a hormone that is produced in humans by the parafollicular cells (commonly known as C-cells) of the thyroid gland. Calcitonin is involved in helping to regulate levels of calcium and phosphate in the blood, opposing the action of parathyroid hormone. The secretion of calcitonin is also inhibited by the hormone somatostatin which is also released by the C-cells in the thyroid gland. What happens if I have too much calcitonin? There does not seem to be any effect on the body as a result of having too much calcitonin. Introduction. Calcitonin is produced by the parafollicular C cells of the thyroid. This hormone is thought to function in calcium and phosphorous metabolism, essentially opposing the effects of parathyroid hormone. In addition, calcitonin represents the classical clinical marker for medullary thyroid carcinoma (MTC). An elevated serum calcitonin level is a highly sensitive marker for medullary thyroid carcinoma (MTC) that can be used for screening, differential diagnosis, prognostic assessment, follow-up monitoring, and assessment of treatment response. Calcitonin, which is produced by your thyroid gland, serves to lower blood calcium levels. It counters the actions of parathyroid hormone. Calcitonin inhibits osteoclast function, slowing the breakdown of bone. Calcitonin's effects on blood calcium levels are small in comparison to parathyroid hormone's influence. High levels of calcitonin, which may be caused by a thyroid tumor, generally do not result in elevated blood calcium. DRUG CLASS: Calcitonin salmon is a man-made version of the hormone, calcitonin, that is found in salmon. Calcitonin is used for treating postmenopausal (after menopause) osteoporosis (bone loss), Paget's disease of bone, and hypercalcemia (high blood calcium levels). Calcitonin is a naturally occurring hormone. It helps regulate calcium levels in your body and is involved in the process of bone building. When taken by shot or nasal spray, it slows the rate of bone thinning. Calcitonin may be used in men with osteoporosis who have normal levels of the male sex hormone testosterone or whose osteoporosis does not get better with testosterone treatment. Miacalcin (calcitonin-salmon) is a man-made form of a hormone that occurs naturally in the thyroid gland used to treat Paget's disease of bone, postmenopausal osteoporosis, or high levels of calcium in the blood (hypercalcemia).  People at increased risk of fractures may also be given calcitonin to reduce the possibility of a bone fracture, and to decrease the severity of fractures when they do occur. This hormone is produced in the thyroid under normal conditions. It interacts with calcitonin receptors on the bone to inhibit the natural breakdown of bone, and control the overall amount of calcium in the bloodstream. When a doctor suspects that a patient has a thyroid disorder, particularly cancer, he or she may order a calcitonin test. In this test, a sample of blood is taken to determine how much of the hormone is in the blood. The patient may also be given injections of calcium to test the body's response. Calcitonin is released by the thyroid gland if the amount of calcium in the bloodstream is high. Calcitonin decreases the amount of calcium and phosphorus in the blood. It does this by slowing the activity of cells found in bone, called osteoclasts. These cells cause calcium to be released as they 'clean' bone. However, parathyroid hormone and calcitonin work together to control calcium levels in the blood. The blood calcium level is the main stimulus for the release of these hormones, as the release of these hormones is not controlled by the pituitary.
http://www.yourhormones.info/hormones/calcitonin.aspx http://www.yourhormones.info/hormones/calcitonin.aspx http://www.medscape.com/viewarticle/586210 http://www.livestrong.com/article/110719-hormones-regulate-blood-calcium-levels/ http://www.medicinenet.com/calcitonin/article.htm http://www.webmd.com/osteoporosis/calcitonin-for-osteoporosis http://www.rxlist.com/miacalcin-side-effects-drug-center.htm http://www.wisegeekhealth.com/what-is-calcitonin.htm http://patient.info/health/the-thyroid-and-parathyroid-glands
is calcitonin bad