Movantik is a prescription medication used to treat opioid-induced constipation in adults with chronic non-cancer pain. Movantik belongs to a group of drugs called mu-receptor opioid antagonists.
print_label | resize_label. NOW AVAILABLE: Learn More. MOVANTIK is the first once daily oral therapy in its class indicated for the treatment of opioid-induced constipation (OIC) in adults with chronic non-cancer pain. Learn about the mechanism of action of MOVANTIK. Watch the video. Learn about the mechanism of action of MOVANTIK. 1 MOVANTIK ™ (naloxegol) is contraindicated in: 2  Patients with known or suspected gastrointestinal (GI) obstruction and patients at increased risk of recurrent obstruction, due to the potential for GI perforation. The U.S. Food and Drug Administration today approved Movantik (naloxegol), an oral treatment for opioid-induced constipation in adults with chronic non-cancer pain. Opioids are a class of drugs that are used to treat and manage pain. MOVANTIK (naloxegol) tablets for oral use contain 14.2 mg and 28.5 mg of naloxegol oxalate, respectively equivalent to 12.5 mg and 25 mg of naloxegol. Excipients in tablet core are: mannitol, cellulose microcrystalline, croscarmellose sodium, magnesium stearate, and propyl gallate. Naloxegol oxalate is a white to off-white powder, with high aqueous solubility across the physiologic pH range. MOVANTIK (naloxegol) tablets for oral use contain 14.2 mg and 28.5 mg of naloxegol oxalate, respectively equivalent to 12.5 mg and 25 mg of naloxegol. Excipients in tablet core are: mannitol, cellulose microcrystalline, croscarmellose sodium, magnesium stearate, and propyl gallate. by The GoodRx Pharmacist on September 22, 2014 at 3:24 pm. Movantik (naloxegol) is a new drug for the treatment of opioid-induced constipation in adult with chronic non-cancer pain—basically, it’s used to prevent constipation when you’re prescribed an opioid for pain relief. It was approved by the FDA on September 16, 2014, and should be available in the first half of 2015.  IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK. 1  MOVANTIK may cause serious side effects, including: 2  Tear in your stomach or intestinal wall (perforation). 3  Opioid withdrawal. 4  Do not take MOVANTIK if you: 5  Have a bowel blockage (intestinal obstruction) or have a history of bowel blockage. 6  Are allergic to MOVANTIK or any of the ingredients in MOVANTIK. 7  Te 1 Tear in your stomach or intestinal wall (perforation). 2  Stomach pain that is severe can be a sign of a serious medical condition. 3  If you get stomach pain that does not go away, stop taking MOVANTIK and get emergency medical help right away. 4 Release. The U.S. Food and Drug Administration today approved Movantik (naloxegol), an oral treatment for opioid-induced constipation in adults with chronic non-cancer pain. Opioids are a class of drugs that are used to treat and manage pain. Movantik’s safety and effectiveness were established in two clinical trials of 1,352 participants who had taken opioids for at least four weeks for non-cancer related pain and had opioid-induced constipation. Updated: Movantik is a prescription medication used to treat opioid-induced constipation in adults with chronic non-cancer pain. Movantik belongs to a group of drugs called mu-receptor opioid antagonists. These work by blocking the effects of opioids in the gastrointestinal tract. This medication comes in oral tablet form and is taken once daily on an empty stomach. Naloxegol (INN; PEGylated naloxol; trade names Movantik and Moventig) is a peripherally-selective opioid antagonist developed by AstraZeneca, licensed from Nektar, for the treatment of opioid-induced constipation. It was approved in 2014 in adult patients with chronic, non-cancer pain. 
https://www.movantikhcp.com/ http://www.rxlist.com/movantik-drug.htm http://www.rxlist.com/movantik-drug.htm http://www.goodrx.com/blog/movantik-new-fda-approved-drug-for-constipation/ https://www.movantik.com/ http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm414620.htm http://www.rxwiki.com/movantik https://en.wikipedia.org/wiki/Naloxegol
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