It is used to prevent nausea and vomiting caused by certain cancer treatments, including chemotherapy, radiation therapy, and surgery.
Uses. This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It is also used to prevent and treat nausea and vomiting after surgery in adults. Granisetron belongs to a class of medications called 5-HT3 blockers. It works by blocking one of the body's natural substances (serotonin) that can cause vomiting. Dosage is based on your medical condition and response to treatment. The dosage may also be based on weight. Use this medication exactly as directed to get the most benefit from it. Do not use more medication or use it more often than prescribed. What Is Granisetron Used For? Granisetron hydrochloride (Kytril ®) is a prescription medication approved for the prevention of nausea and vomiting due to chemotherapy or radiation. An injectable form of granisetron is also available and is used to prevent nausea and vomiting due to chemotherapy or surgery. Granisetron works by blocking serotonin, a chemical produced by the body that is associated with nausea and vomiting. Serotonin has many effects in the body and has several receptors where it can bind. Its empirical formula is C18H24N4O•HCl, while its chemical structure is: granisetron hydrochloride. Granisetron hydrochloride is a white to off-white solid that is readily soluble in water and normal saline at 20°C. Limit alcoholic beverages. Granisetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting)... A Stacy Wiegman, PharmD, Pharmacy, answered. Granisetron hydrochloride is a prescription medication that's used to prevent nausea and vomiting caused by certain cancer treatments, including chemotherapy, radiation therapy, and surgery. When taken by an injection, Granisetron hydrochloride is given by a health care professional in a hospital or clinic and it may be administered as a 30-second injection or mixed into IV fluid and infused over five minutes. Granisetron hydrochloride is a type of medication called a 5-HT3 blocker and it works by blocking serotonin, which is a chemical in the body that can cause vomiting. When taken by an injection, Granisetron hydrochloride is given by a health care professional in a hospital or clinic and it may be administered as a 30-second injection or mixed into IV fluid and infused over five minutes. It may be used for chemotherapy-induced nausea and vomiting and appears to work about the same as ondansetron. The most common side-effects of chemotherapy treatment are nausea, vomiting and diarrhea. This is one type of drug that a doctor can prescribe to prevent, lessen, or relieve discomfort. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. A granisetron transdermal patch with the trade name Sancuso was approved by the US FDA on September 12, 2008. Sancuso is manufactured by 3M Drug Delivery Systems Division in St. Paul, MN, for ProStrakan, Inc., a pharmaceutical company headquartered in Bedminster, NJ, with global headquarters in Scotland. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. From Wikipedia, the free encyclopedia. Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. granisetron hydrochloride. Granisetron hydrochloride is a white to off-white solid that is readily soluble in water and normal saline at 20°C. KYTRIL Injection is a clear, colorless, sterile nonpyrogenic, aqueous solution for intravenous administration. KYTRIL 1 mg/mL is available in 1 mL single-use and 4 mL multi-use vials. 0.1 mg/mL: Each 1 mL contains 0.112 mg granisetron hydrochloride equivalent to granisetron, 0.1 mg; sodium chloride, 9 mg; citric acid, 2 mg. Contains no preservative. The solution's pH ranges from 4.0 to 6.0
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what is granisetron hcl used for