Attacks of muscle weakness or paralysis when the level of potassium in the blood drops. Reduced levels of potassium in their blood (hypokalemia) during episodes of muscle weakness.
Hypokalemic periodic paralysis is an inherited disorder that causes occasional episodes of muscle weakness. It is one of a group of genetic disorders that includes hyperkalemic periodic paralysis and thyrotoxic periodic paralysis. Attacks that do not begin until adulthood are rare in people with hypokalemic periodic paralysis and are usually caused by other disorders. How often the attacks occur varies. Some people have attacks every day, while others have them once a year. Episodes of muscle weakness usually last between a few hours and a day. Hypokalemic periodic paralysis is a disorder that causes occasional episodes of muscle weakness and sometimes a lower than normal level of potassium in the blood. It is one of a group of genetic disorders that includes. and. 1  hyperkalemic periodic paralysis. Definition. Hypokalemic periodic paralysis is a disorder that causes occasional episodes of muscle weakness and sometimes a lower than normal level of potassium in the blood. It is one of a group of genetic disorders that includes. and. 1  hyperkalemic periodic paralysis. 2  thyrotoxic periodic paralysis. Hypokalemic periodic paralysis causes attacks of muscle weakness or paralysis when the level of potassium in the blood drops. During severe attacks the patient may be unable to move and even appear unconscious. Even during paralysis the patient is awake and completely aware of their surroundings. Hypokalemic Periodic Paralysis (HypoKPP) is a rare inherited muscle disorder which is estimated to occur in only one of 100,000 individuals. Hypokalemic periodic paralysis. From Wikipedia, the free encyclopedia. Hypokalemic periodic paralysis is a rare, autosomal dominant channelopathy characterized by muscle weakness or paralysis with a matching fall in potassium levels in the blood (primarily due to defect in a voltage-gated calcium channel). The prognosis for periodic paralysis varies. Overactivity, a diet that is not low in sodium and carbohydrates, or simply an unfortunate gene mutation can lead to a type of chronic, low level weakness called an abortive attack, or to permanent muscle damage. Hypokalemic periodic paralysis: Related Medical Conditions. To research the causes of Hypokalemic periodic paralysis, consider researching the causes of these these diseases that may be similar, or associated with Hypokalemic periodic paralysis: 1  Genetic disease. 2  Hyperthyroidism. 3  Paramyotonia congenital. 4  Anderson-Tawil syndrome. 5  Clinodacttly. 6  Micrognathia.  People with hypokalemic periodic paralysis have reduced levels of potassium in their blood (hypokalemia) during episodes of muscle weakness. Researchers are investigating how low potassium levels may be related to the muscle abnormalities in this condition. A small percentage of people with the characteristic features of hypokalemic periodic paralysis do not have identified mutations in the CACNA1S or SCN4A gene. In these cases, the cause of the condition is unknown. Back to Top Causes. Hypokalemic periodic paralysis is a condition in which a person has episodes of muscle weakness and sometimes severe paralysis. The condition is caused by a defect in the the CNA4A gene. It is congenital, which means it is present from birth. Attacks that do not begin until adulthood are rare in people with hypokalemic periodic paralysis and are usually caused by other disorders. How often the attacks occur varies. Some people have attacks every day, while others have them once a year. Episodes of muscle weakness usually last between a few hours and a day.
http://www.nytimes.com/health/guides/disease/hypokalemic-periodic-paralysis/overview.html http://umm.edu/health/medical/ency/articles/hypokalemic-periodic-paralysis http://hkpp.org/patients/hypokpp-FAQ https://en.wikipedia.org/wiki/Hypokalemic_periodic_paralysis http://www.rightdiagnosis.com/h/hypokalemic_periodic_paralysis/causes.htm http://ghr.nlm.nih.gov/condition/hypokalemic-periodic-paralysis http://www.nytimes.com/health/guides/disease/hypokalemic-periodic-paralysis/overview.html
causes of hypokalemic periodic paralysis