Plasma cells
1 IgM antibodies are the largest antibody. 2  They are found in blood and lymph fluid and are the first type of antibody made in response to an infection. 3  They also cause other immune system cells to destroy foreign substances. 4  IgM antibodies are about 5% to 10% of all the antibodies in the body. Antibodies are substances made by the body's immune system in response to bacteria, viruses, fungus, animal dander, or cancer cells. Antibodies attach to the foreign substances so the immune system can destroy them. Antibodies are specific to each type of foreign substance. Monoclonal antibodies to treat cancer. One way the immune system attacks foreign substances in the body is by making large numbers of antibodies. An antibody is a protein that sticks to a specific protein called an antigen. Antibodies circulate throughout the body until they find and attach to the antigen. Once attached, they can recruit other parts of the immune system to destroy the cells containing the antigen. B lymphocytes are the white blood cells that produce plasma cells  that produce antibodies. Antibodies are special proteins that  recognize foreign materials and help the bo … dy destroy or neutralize  them.    The type of white blood cell that secretes antibodies to kill  microorganisms is called lymphocytes.  Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shape protein produced by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. The antibody recognizes a unique molecule of the harmful agent, called an antigen, via the variable region Though strictly speaking, an antibody is not the same as an immunoglobulin; B cells can produce two types of immunoglobulins-surface immunoglobulins, which are B cell receptors; and secreted immunoglobulins, which are antibodies. So antibodies are one of two classes of immunoglobulins. An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shape protein produced by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. Rating Newest Oldest. Best Answer: Your body makes antibodies when it comes in contact with an antigen. An antigen is any substance that your immune system recognizes as foreign and causes your body to initiate an immune response. If your body makes antibodies all of the time you most likely have what is known as an autoimmune disorder (an overactive immune system attacks normal body cells.) Or you have a chronic infection (such as HIV or Hepatitis)and your body is attempting to fight it off. Polyclonal Antibodies vs. Monoclonal Antibodies. Polyclonal Antibodies. The immune response to an antigen generally involves the activation of multiple B-cells all of which target a specific epitope on that antigen. As a result a large number of antibodies are produced with different specificities and epitope affinities these are known as polyclonal antibodies.  IgM is not only the first class of antibody to appear on the surface of a developing B cell. It is also the major class secreted into the blood in the early stages of a primary antibody response, on first exposure to an antigen. Antibodies defend us against infection by binding to viruses and microbial toxins, thereby inactivating them (see Figure 24-2). The binding of antibodies to invading pathogens also recruits various types of white blood cells and a system of blood proteins, collectively called complement (discussed in Chapter 25). Antibodies recognize specific antigens by identifying certain areas on the surface of the antigen known as antigenic determinants. Once the specific antigenic determinant is recognized, the antibody will bind to the determinant. The antigen is tagged as an intruder and labeled for destruction by other immune cells. The antigen-binding site is the area of the antibody that recognizes the specific antigenic determinant and binds to the antigen. Since different antibodies recognize different antigens, antigen-binding sites are different for different antibodies. This area of the molecule is known as the variable region. Antibodies (also known as immunoglobulins, abbreviated Ig) are gamma globulin proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immun … e system to identify and neutralize foreign objects, such as bacteria and viruses. More Information: Antibodies (also known as immunoglobulins, abbreviated Ig) are gamma globulin proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immun
http://www.webmd.com/a-to-z-guides/immunoglobulins http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/immunotherapy/immunotherapy-monoclonal-antibodies http://www.answers.com/Q/Which_cells_make_antibodies https://en.wikipedia.org/wiki/Antibody https://en.wikipedia.org/wiki/Antibody https://answers.yahoo.com/question/index?qid=20090103234532AAia3oy http://www.randox-lifesciences.com/Article/ViewArticle/57?path=Polyclonal%20vs.%20Monoclonal&20Antibodies&articleSectionId=1 http://www.ncbi.nlm.nih.gov/books/NBK26884/ http://biology.about.com/od/molecularbiology/ss/antibodies.htm http://www.answers.com/Q/What_Makes_Antibodies
what makes antibodies