Prontosil, the first of the family of sulfa drugs.
He is credited with the discovery of Sulfonamidochrysoidine (KI-730) – the first commercially available antibiotic (marketed under the brand name Prontosil) – for which he received the 1939 Nobel Prize in Physiology or Medicine. Domagk was born in Lagow, Brandenburg, the son of a school headmaster. Until he was 14, he attended school in Sommerfeld (now Lubsko, Poland). In 1939, Domagk received the Nobel Prize in Medicine for this discovery, the first drug effective against bacterial infections. He was forced by the Nazi regime to refuse the prize and was arrested by the Gestapo for a week. Gerhard Domagk. Gerhard Domagk was born in 1895 in Lagow, Brandenburg, as the son of a teacher. At the age of 20, Domagk — who would later go on to win a Nobel Prize — was confronted with the supposed limits of medicine through his experiences in World War I. At that time, operations that were initially successful were often marred by fatal infectious diseases such as gangrene or gas gangrene. In 1932, while searching for a way to combat bacterial infections by chemical means, Domagk stumbled upon the active substance dimethyl benzyl dodecyl ammonium chloride, which was later launched on the market as a 10 percent solution under the trade name Zephirol. The discovery of the antibacterial action of the sulphonamides was not, however, Domagk's only contribution to chemotherapy. He also discovered the therapeutic value of the quaternary ammonium bases and he also extended, in collaboration with Klarer and Mietzsch, his work on the sulphonamides. His mother, Martha Reimer, came from farming stock in the Marches, where she lived in Sommerfeld until 1945 when she was expelled from her home; she died from starvation in a refugee camp. Domagk himself was, from the age of 14, at school in Silesia until he reached the upper sixth form. For his discovery of prontosil's therapeutic effect, Dr Domagk was named a Nobel Prize winner in 1939, but he was ordered by Nazi authorities to decline the honor. His mother was driven from their family home, and starved to death in a refugee camp. Military service: German Army (1914-18). German chemist and pathologist Gerhard Domagk researched infections caused by bacteria, and found that an industrial dye, prontosil rubrum, had antibacterial action that proved an effective treatment for staphylococci and haemolytic streptococci. The story and subsequent media attention kicked off America’s great sulfa boom. German scientist Gerhard Domagk was the invented Protonsil, the first of the family of sulfa drugs, in 1935 Prontosil, the first of the family of sulfa drugs, started out its life not as an antibiotic but as an industrial dye. For a long period, humans did not understand what caused disease, much less how to treat pathogenic illness. However, since the end of the 19th century, medical science began to understand the true roots of illnesses caused by pathogens, such as harmful bacteria and viruses. Gerhard Domagk-Biographical. Gerhard Johannes Paul Domagk was born on October 30, 1895, at Lagow, a beautiful, small town in the Brandenburg Marches. Until he was fourteen he went to school in Sommerfeld, where his father was assistant headmaster. His mother, Martha Reimer, came from farming stock in the Marches, where she lived in Sommerfeld until 1945 when she was expelled from her home; she died from starvation in a refugee camp. Domagk himself was, from the age of 14, at school in Silesia until he reached the upper sixth form. Born: 30 October 1895, Lagow, Germany (now Poland). Died: 24 April 1964, Burgberg, West Germany (now Germany). Affiliation at the time of the award: Munster University, Munster, Germany. Prize motivation: for the discovery of the antibacterial effects of prontosil. Field: bacteriology. Gerhard Domagk was caused by the authorities of his country to decline the award but he later received the diploma and the medal.
https://en.wikipedia.org/wiki/Gerhard_Domagk http://www.bayer.com/en/Gerhard-Domagk.aspx http://www.nobelprize.org/nobel_prizes/medicine/laureates/1939/domagk-bio.html http://www.nndb.com/people/744/000128360/ http://www.randomhistory.com/antibiotics-history.html http://www.nobelprize.org/nobel_prizes/medicine/laureates/1939/domagk-bio.html http://www.nobelprize.org/nobel_prizes/medicine/laureates/1939/domagk-facts.html
what did gerhard domagk invent