8 hours 43 minutes
– Take I-75 south to southwestern Ohio, then I-71 south into Louisville, KY. Take I-64 west into Indiana. Stay on I-64 west for nearly an hour, then take Exit 63. Turn left (south) onto Highway 162 and drive 7 miles until the road comes to a stoplight. Proceed straight at the light into the Holiday World parking lot. Since this is a long drive, you might want to stop halfway and stay overnight in a hotel. You can find the city that is halfway between Saint Louis, MO and Detroit, MI. From St. Louis, Missouri. – Drive on I-64 east for approximately 3 hours; take Exit #57-A South and head south on US 231 to the State Road 162 exit, which will take you directly into the town of Santa Claus and to the Holiday World parking lots. Merge onto I-71 south and stay on it for approximately 1 hour and 10 minutes, then take Exit 1 to I-64 west. Continue on I-64 west for approximately 1 hour then take Exit 63. Turn left (south) onto Highway 162 and drive 7 miles until the road comes to a stoplight. Your trip begins in Saint Louis, Missouri. It ends in Detroit, Michigan. If you're planning a road trip, you might be interested in seeing the total driving distance from Saint Louis, MO to Detroit, MI. How long is the drive from Detroit, MI to Saint Louis, MO? The total driving time is 8 hours, 43 minutes. You can also calculate the cost to drive from Saint Louis, MO to Detroit, MI based on current local gas prices and an estimate of your car's best gas mileage. The distance between Missouri, USA, and Detroit, MI, is 660 miles and will take about 10 Hours 20 Minutes of driving time. The driving distance between Detroit, MI and Nashville, TN is approximately 535 miles. The driving time would be approximately 8 hours 30 minutes if you were to travel non-sto … p in good driving conditions. 552 mi (888km) - about 8 hours 39 mins Saint Louis, MO, USA to Detroit, MI, USA.
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