Propofol marketed as Diprivan, is a short-acting, intravenously administered hypnotic/amnestic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is sedation for medical procedures accomplished with the use of propofol, a hypnotic agent used to induce anesthesia and manage patients on mechanical ventilators.
Reviewed by Laura J. Martin, MD. Propofol is a strong anesthetic that's used for surgery, some medical exams, and for sedation for people on ventilators -- never as a sleep aid. It's given by IV and should only be administered by a medical professional trained in its use. It takes effect in a matter of seconds. Propofol is a potentially deadly drug in the wrong hands, and there is no room for error. It's only designed for people trained to do advanced cardiac life support , Dombrowski says. It induces a deep level of sleep and sedation, and it can cause your blood pressure to go down and your breathing to stop. You can die. Problem: Using propofol (DIPRIVAN) to sedate patients during endoscopic and other diagnostic procedures is gaining momentum in a growing number of hospitals, outpatient surgery centers, and physician offices.(1) In trained hands, propofol offers many advantages over other drugs used for sedation because it:  Propofol marketed as Diprivan, is a short-acting, intravenously administered hypnotic / amnestic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. The half-life of elimination of propofol has been estimated to be between 2 and 24 hours. However, its duration of clinical effect is much shorter, because propofol is rapidly distributed into peripheral tissues. When used for IV sedation, a single dose of propofol typically wears off within minutes. These 10 animal facts will amaze you. Propofol sedation is sedation for medical procedures accomplished with the use of propofol, a hypnotic agent used to induce anesthesia and manage patients on mechanical ventilators. Some facilities prefer to use an anesthesiologist or nurse-anesthetist for propofol sedation, as these care providers have special training in the administration of anesthesia and the potential complications. Propofol is also used for procedural sedation, for example during endoscopic procedures. Its use in these settings results in a faster recovery compared to midazolam. Because of its fast induction and recovery time, propofol is also widely used for sedation of infants and children undergoing MRI. The half-life of elimination of propofol has been estimated to be between 2 and 24 hours. However, its duration of clinical effect is much shorter, because propofol is rapidly distributed into peripheral tissues. When used for IV sedation, a single dose of propofol typically wears off within minutes. Propofol is 98% plasma-protein bound, and is metabolized primarily in the liver. The drug is lipophilic and is prepared as an oil/water emulsion consisting of 1% propofol, 10% soybean oil, 2.25% glycerol, and 1.2% egg lecithin. Propofol is contraindicated in patients with hypersensitivity to eggs or soybean. Propofol is an FDA approved anesthetic agent used for the induction and maintenance of general anesthesia and for sedation in ventilated patients [ 16 ]. It is classified as an ultrashort-acting hypnotic agent. Propofol possesses sedative, amnestic, and hypnotic properties, but minimal levels of analgesia [ 17 ] Propofol is the generic name for Diprivan, which is a prescription, injectable drug. It's an anesthetic used to put people to sleep before surgery. It's also given for sedation in hospital intensive care units (ICUs). Propofol was first approved by the Food and Drug Administration (FDA) in 1989, and is sold as Diprivan by Fresenius Kabi USA. The deaths of two celebrities, Michael Jackson and Joan Rivers, have been linked to misuse or complications of propofol. Pregnancy and Propofol. Propofol is classified by the FDA as a Category B drug for pregnancy. This means that it is not known to cause harm to an unborn baby or fetus.
http://www.webmd.com/pain-management/features/propofol-faq http://www.ismp.org/Newsletters/acutecare/articles/20051103.asp https://en.wikipedia.org/wiki/Propofol http://www.wisegeek.com/what-is-propofol-sedation.htm https://en.wikipedia.org/wiki/Propofol http://www.gastrohep.com/freespeech/freespeech.asp?id=101 http://www.everydayhealth.com/drugs/propofol
what is propofol sedation