In the majority of cases, excess levels of GH are causes by a benign (noncancerous) tumor in the pituitary gland (pituitary adenoma).The pituitary gland is a small gland at the base of the brain that produces several important hormones to control body functions such as growth, development, reproduction, and metabolism.
Acromegaly is most often caused by a benign (non-cancerous) tumor of the pituitary gland that secretes excess growth hormone. In rare cases, acromegaly can be caused by tumors of the pancreas, lungs or adrenal glands. It controls the production of hormones in all endocrine glands. Acromegaly is a condition in which the pituitary gland secretes growth hormone after the normal growth of the skeleton and other organs is complete. In almost all cases, it is caused by a benign (non-cancerous) tumor of the pituitary gland Causes. Acromegaly is a rare disorder that is caused by excess levels of growth hormone (GH) in the body. In the majority of cases, excess levels of GH are causes by a benign (noncancerous) tumor in the pituitary gland (pituitary adenoma). In rare cases, non-pituitary tumors in the pancreas, lungs or adrenal glands may cause acromegaly. These tumors may directly produce excess growth hormone or they may produce growth hormone-releasing hormone (GHRH), which stimulates the pituitary gland to release GH. Continue ReadingAcromegaly Symptoms. Acromegaly is a growth disorder caused by too much growth hormone (GH) being released by the pituitary gland, leading to excessive growth. When GH is released at normal levels, it promotes healthy growth. Too much of it, though, is a serious—but rare —endocrine disorder Acromegaly is a rare but serious condition caused by too much growth hormone (GH) in the blood. GH is released into the bloodstream by the pituitary gland, located at the base of the brain. The blood carries GH to other parts of the body where it has specific effects. In children, GH stimulates growth and development. Acromegaly is usually caused by a non-cancerous tumor in the pituitary gland called a pituitary adenoma. The tumor produces too much GH and raises the level of GH in the blood. In most cases, acromegaly is caused by the growth of a benign tumor (adenoma), affecting the pituitary gland. Symptoms of acromegaly include abnormal enlargement in bones of the hands, arms, feet, legs, and head. In rare cases, non-pituitary tumors in the pancreas, lungs or adrenal glands may cause acromegaly. These tumors may directly produce excess growth hormone or they may produce growth hormone-releasing hormone (GHRH), which stimulates the pituitary gland to release GH. Endocrine Glands Involved in Acromegaly. The pituitary gland is a small gland at the base of the brain that produces several important hormones to control body functions such as growth, development, reproduction, and metabolism. Growth Hormone (GH) is part of a cascade of hormones that is produced by the pituitary gland. Growth hormone-releasing hormone (GHRH) is a hormone produced by the hypothalamus and its function is to stimulate the pituitary gland to produce GH. 1 Growth hormone (GH). 2  GH is made in the pituitary gland (see figure below). 3  In a person with acromegaly, too much GH is released into the body. 4  Overproduction of GH causes changes in physical appearance and body function. Acromegaly is generally caused by a noncancerous growth called a tumor or an adenoma located on the pituitary gland. The pituitary gland is a pea-sized structure located in the front of the brain, behind the eyes (see figure below). It is also commonly referred to as the master gland of the body. Acromegaly is a serious systemic condition caused in over 98% of cases by an adenoma (i.e., benign tumor) of the pituitary gland that secretes excessive growth hormone (GH). 
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what glands are associated with acromegaly