It is caused by a build-up of fatty deposits on the walls of the arteries around the heart (coronary arteries).The fatty deposits, called atheroma, are made up of cholesterol and other waste substances. It is usually caused by a build-up of fatty deposits on the walls of the arteries around the heart (coronary arteries).The fatty deposits, called atheroma, are made up of cholesterol and other waste substances.auses of heart disease.
Coronary heart disease (CHD) is a disease in which a waxy substance called plaque (plak) builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle. When plaque builds up in the arteries, the condition is called atherosclerosis (ATH-er-o-skler-O-sis). CAD, also called coronary heart disease, is the leading cause of death for both men and women in the United States. CAD occurs if plaque builds up in the arteries of the heart. Plaque narrows the arteries and reduces blood flow to the About Coronary Heart Disease (CHD). Coronary heart disease (CHD) is a disease in which a waxy substance called plaque (plak) builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle. When plaque builds up in the arteries, the condition is called atherosclerosis (ATH-er-o-skler-O-sis).  Causes of heart disease. Coronary heart disease (CHD) is usually caused by a build-up of fatty deposits on the walls of the arteries around the heart (coronary arteries). The fatty deposits, called atheroma, are made up of cholesterol and other waste substances.  Coronary artery disease is caused by hardening of the arteries, or atherosclerosis. This means that fatty deposits called plaque build up inside the arteries. Arteries are the blood vessels that carry oxygen-rich blood throughout your body. Atherosclerosis can affect any arteries in the body. When it occurs in the arteries that supply blood to the heart (the coronary arteries), it is called coronary artery disease. Coronary heart disease (CHD), also known as coronary artery disease is a narrowing of the blood vessels (coronary arteries) that supply oxygen and blood to the heart. Sometimes a clot may form which can obstruct the flow of blood to heart muscle. Coronary heart disease commonly causes angina pectoris (chest pain), shortness of breath, heart attack (myocardial infarction) and other symptoms. The coronary arteries are called so because they encircle the heart like a crown. Coronary heart disease is generally caused by atherosclerosis-when plaque (cholesterol substances) accumulates on the artery walls, causing them to narrow, resulting in less blood flow to the heart. Sometimes a clot may form which can obstruct the flow of blood to heart muscle. Coronary heart disease commonly causes angina pectoris (chest pain), shortness of breath, heart attack (myocardial infarction) and other symptoms. The coronary arteries are called so because they encircle the heart like a crown. Heart disease is a result of plaque buildup in your coronary arteries -- a condition called atherosclerosis -- that leads to blockages. The arteries, which start out smooth and elastic, become narrow and rigid, restricting blood flow to the heart. A. A. Coronary artery disease, also called coronary heart disease, or simply, heart disease, is the No. 1 killer in America, affecting more than 13 million Americans. Heart disease is a result of plaque buildup in your arteries, which blocks blood flow and heightens the risk for heart attack and stroke. Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis. CAD is caused by plaque buildup in the walls of the arteries that supply blood to the heart (called coronary arteries) and other parts of the body. Plaque is made up of deposits of cholesterol and other substances in the artery. Coronary heart disease is caused by any problem with the coronary arteries that keeps the heart from getting enough oxygen-and nutrient-rich blood. The most common cause by far is atherosclerosis. Lack of sufficient blood is called ischemia, so coronary heart disease is sometimes called ischemic heart disease. 
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