Vasoconstrictor
The efferent arterioles are blood vessels that are part of the urinary tract of organisms. The efferent arterioles form from a convergence of the capillaries of the glomerulus. They play an important role in maintaining the glomerular filtration rate despite fluctuations in blood pressure. The efferent arterioles of the juxtamedullary glomeruli are much different. They do break up, but they form bundles of vessels (arteriolae recti) that cross the outer zone of the medulla to perfuse the inner zone. In summary, thapsigargin treatment markedly attenuates juxtamedullary afferent arteriolar vasoconstrictor responses to Ang II or NE. In addition, depletion of intracellular calcium pools with thapsigargin completely abolishes the response of juxtamedullary efferent arterioles to these vasoconstrictor agents. These studies were conducted to determine the role of calcium release from the thapsigargin-sensitive intracellular calcium pool on the Ang II-and NE-mediated vasoconstriction of juxtamedullary afferent and efferent arterioles. The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems. They play an important role in the regulation of blood pressure as a part of the tubuloglomerular feedback mechanism. The afferent arterioles branch from the renal artery, which supplies blood to the kidneys. The afferent arterioles later diverge into the capillaries of the glomerulus.  arteriole. afferent glomerular arteriole a branch of an interlobular artery that goes to a renal glomerulus. efferent glomerular arteriole one arising from a renal glomerulus, breaking up into capillaries to supply renal tubules. postglomerular arteriole efferent glomerular a. precapillary arteriole arterial capillary. preglomerular arteriole afferent glomerular a. straight arterioles of kidney branches of the arcuate arteries of the kidney arising from the efferent glomerular arterioles and passing down to the renal pyramids When Arterioles are in series, the combined Resistance is higher than the individual Resistances. The Afferent Arteriole is in Series with the Efferent Arteriole. Increasing the Resistance of EITHER ONE increases the Total Resistance of the Kidney and reduces Renal blood flow (& vice versa). Constriction of BOTH Afferent & Efferent Arterioles, with preferential Constriction of the Efferent Arteriole. This results in a massive reduction in RBF/RPF and an increased in GFR. These are active under pathologic conditions (e.g. hemorrhage) NOT physiologic conditions. The magnitude of the efferent arteriolar vasoconstriction evoked by 10 nmol/L Ang II was not significantly different from the afferent arteriolar response to the same Ang II concentration. The response of efferent arterioles to thapsigargin treatment was similar to the response of afferent arterioles. These studies were conducted to determine the role of calcium release from the thapsigargin-sensitive intracellular calcium pool on the Ang II-and NE-mediated vasoconstriction of juxtamedullary afferent and e The remarkable difference in the efficacy of thapsigargin treatment in altering afferent and efferent arteriolar responsiveness to Ang II and NE strongly suggests that calcium release from thapsigargin-sensitive intracellular stores plays a pivotal role in the ability of efferent arterioles to respond to these agents. These studies were conducted to determine the role of calcium release from the thapsigargin-sensitive intracellular calcium pool on the Ang II-and NE-mediated vasoconstriction of juxtamedullary afferent and efferent arterioles.
https://en.wikipedia.org/wiki/Efferent_arteriole http://hyper.ahajournals.org/content/29/1/222.full https://en.wikipedia.org/wiki/Afferent_arterioles http://medical-dictionary.thefreedictionary.com/arteriole https://quizlet.com/33909680/glomerular-filtration-renal-blood-flow-flash-cards/ http://hyper.ahajournals.org/content/29/1/222.full http://hyper.ahajournals.org/content/29/1/222.full
what type of response by the afferent arterioles