Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
NK cells become activated upon stimulation by the cytokines IL-2, IL-15, IL-15RA in complex with IL-15, IL-18 and IL-12 to produce a large variety of cytokines and chemokines that includes IFNγ, TNFα, IL-17 and IL-22 to name a few. Unlike most lymphoid cells, NK cells are part of the innate immune system and mediate their effect in an antigen independent manner that in general does not give rise to immunological memory or protective immunity. White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All leukocytes are produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. White cells are found in the buff, a thin, typically white layer of nucleated cells between the sedimented red blood cells and the blood plasma. The scientific term leukocyte directly reflects its description. The role NK cells play is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to viral-infected cells and respond to tumor formation, acting at around 3 days after infection. This role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release. Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system. This role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release. Q. What is the common name and the scientific name for brain cells. Answered By: Emilie Smart. Last Updated: Sep 26, 2015 Views: 5062. Brain cell is a generic term for the neurons and glial cells. Neurons are nerve cells that process and transmit information through the nervous system. Glial cells provide support, protection, and nutrition to the neurons. Other cells in the brain include epithelial cells that make up the lining of the blood vessels. The common names for certain brain cells that you may be looking for are gray and white matter. See the Credo Reference link Brain below. Here are some websites that will help answer your question: In addition to the knowledge that natural killer cells are effectors of innate immunity, recent research has uncovered information on both activating and inhibitory NK cell receptors which play important function roles including self tolerance and sustaining NK cell activity. This role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release. NK cells (belonging to the group of innate lymphoid cells) are defined as large granular lymphocytes (LGL) and constitute the third kind of cells differentiated from the common lymphoid progenitor-generating B and T lymphocytes. This role of NK cells is critical to immune success particularly because T cells are unable to recognize pathogens in the absence of surface antigens. Tumor cell detection results in activation of NK cells and consequent cytokine production and release. Similar to cytolytic CD8+ T cells, NK cells contain a variety of proteins that mediate the destruction of target cells by inducing a program of apoptotic cell death. NK cells are characterized by the presence of cytoplasmic granules that contain proteins such as perforin and granzymes. Unlike most lymphoid cells, NK cells are part of the innate immune system and mediate their effect in an antigen independent manner that in general does not give rise to immunological memory or protective immunity. 1 NK cells have. 2  activating receptors, that activate the NK cell when it binds to a target cell, and. 3  inhibitory receptors that transmit an inhibitory signal if they encounter class I MHC molecules on a cell surface. Perhaps the function of NKT cells is to provide quicker help for a cell-mediated immune response (IFN-γ) or antibody-mediated response (IL-4) than the several days needed by conventional T-helper cells. If so, NKT cells would represent a link between innate and adaptive immunity.
http://www.ebioscience.com/knowledge-center/antigen/cytokines/nk-cells.htm https://en.wikipedia.org/wiki/White_blood_cell https://en.wikipedia.org/wiki/Natural_killer_cell https://en.wikipedia.org/wiki/Natural_killer_cell http://ebrpl.libanswers.com/faq/15630 https://en.wikipedia.org/wiki/Natural_killer_cell https://en.wikipedia.org/wiki/Natural_killer_cell http://www.ebioscience.com/knowledge-center/antigen/cytokines/nk-cells.htm http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/N/NK_Cells.html
what are NK cells, scientific name