These diseases that may be similar, or associated with Erdheim-Chester Disease: 1 Polyostotic sclerosing histiocytosis. 2 Bone pain. 3 Retroperitoneal fibrosis. 4 Diabetes insipidus. 5 Exophthalmos. 6 Dyspnea. 7 Ataxia.
Erdheim-Chester disease is a non-Langerhans cell histiocytosis that is progressive and may lead on to multi-organ involvement. Pulmonary involvement is rare, its presentation is nonspecific, and it carries an adverse outcome. Several radiological features, when considered together, may point to the diagnosis. Erdheim-Chester Disease: Related Medical Conditions. To research the causes of Erdheim-Chester Disease, consider researching the causes of these these diseases that may be similar, or associated with Erdheim-Chester Disease: 1  Polyostotic sclerosing histiocytosis. 2  Bone pain. 3  Retroperitoneal fibrosis. 4  Diabetes insipidus. 5  Exophthalmos. 6  Dyspnea. 7  Ataxia. The exact cause of Erdheim-Chester disease (ECD) is unknown. However, the disease is thought to represent an abnormal inflammatory process characterized by excessive proliferation and accumulation of certain cells, with associated scarring or overgrowth of fibrous connective tissue (fibrosis). Erdheim-Chester disease (ECD) is a rare non-Langerhans cell, non-familial multisystemic granulomatosis, with widespread manifestations and of highly variable severity. The most common presenting symptom is bone pain. Erdheim-Chester disease (ECD) is a rare multisystem disorder of adulthood. It is characterized by excessive production and accumulation of histiocytes within multiple tissues and organs. Histiocytes are large phagocytic cells (macrophages) that normally play a role in responding to infection and injury.
http://www.ncbi.nlm.nih.gov/pubmed/17304381 http://www.rightdiagnosis.com/e/erdheim_chester_disease/causes.htm http://rarediseases.org/rare-diseases/erdheim-chester-disease/ http://radiopaedia.org/articles/erdheim-chester-disease http://rarediseases.org/rare-diseases/erdheim-chester-disease/
cause of erdheim-chester disease