BAX is a member of the Bcl-2 gene family.
BAX expression is regulated by p53, the tumour suppressor, and is involved in p53-mediated apoptosis. Bax. A 21-kD protein encoded by BAX, located on chromosome 19q13.3-q13.4, which has significant homology with Bcl-2, the apoptosis repressor, with which it forms a heterodimer. Overexpression of Bax compared to Bcl-2 signifies apoptosis. DEFINITION of 'BAX Contract'. A BAX contract is a short-term investment instrument that uses a Canadian banker's acceptance (BA) as its underlying security. The specific BA underlying the contract has a nominal value of C$1 million and a maturity of three months. The contracts are traded on the Montreal Derivatives Exchange. BREAKING DOWN 'BAX Contract'. These contracts are great way for a company to hedge against a rise in interest rates. BAX contracts are becoming increasingly popular because they are a less expensive hedge than their over-the-counter competition, forward rate agreements. Bax has 1 related variation via Baxter: Baxley. Bax is an uncommonly occurring first name for men but a very prominent last name for both adults and children (#15809 out of 150436, Top 11%). (2000 U.S. Census). Below is a graphed comparison of the popularity of the boy name Bax and corresponding names. Bax /bax/ [1 syll.] as a name for boys is of Old English derivation, and the meaning of the name Bax is baker. Bax is an alternate form of Baxter (Old English). Bix is a common last name Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family members form hetero-or homodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The BAX gene was the first identified pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero-or homodimers. Sir Arnold Edward Trevor Bax, KCVO (8 November 1883 – 3 October 1953) was an English composer, poet, and author. His prolific output includes songs, choral music, chamber pieces, and solo piano works, but he is best known for his orchestral music. Between 1910 and 1920 Bax wrote a large amount of music, including the symphonic poem Tintagel, his best-known work. During this period he formed a lifelong association with the pianist Harriet Cohen – at first an affair, then a friendship, and always a close professional relationship. Entrez Gene Summary for BAX Gene. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero-or homodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. BAX (BCL2-Associated X Protein) is a Protein Coding gene. BAX. A gene located on chromosome 19q13.3-q13.4, which encodes Bax, which belongs to the BCL2 family of proteins with which it forms a heterodimer, together acting as anti-or pro-apoptosis regulators, depending on whether Bax or Bcl-2 is greater. Bax. A 21-kD protein encoded by BAX, located on chromosome 19q13.3-q13.4, which has significant homology with Bcl-2, the apoptosis repressor, with which it forms a heterodimer. Overexpression of Bax compared to Bcl-2 signifies apoptosis. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis. The p53 protein is a transcription factor that, when activated as part of the cell's response to stress, regulates many downstream target genes, including BAX. The BAX gene was the first identified pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero-or homodimers. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero-or homodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. 1 In the exone 3 of the gene Bax mutation G7/G9 in cells SKOV3 results in an inactivation of proapoptotic activity of the protein Bax. 2  BAX is required for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
http://medical-dictionary.thefreedictionary.com/Bax http://www.investopedia.com/terms/b/bax.asp http://www.thinkbabynames.com/meaning/1/Bax https://en.wikipedia.org/wiki/Bcl-2-associated_X_protein https://en.wikipedia.org/wiki/Arnold_Bax http://www.genecards.org/cgi-bin/carddisp.pl?gene=BAX http://medical-dictionary.thefreedictionary.com/Bax https://en.wikipedia.org/wiki/Bcl-2-associated_X_protein http://www.ncbi.nlm.nih.gov/gene/581
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