A histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface.
Histiocytoma is a common, benign, cutaneous neoplasm of the dog. Histiocytomas usually occur as solitary lesions which undergo spontaneous regression. Epidermal invasion in histiocytoma, or presence of simultaneous multiple histiocytomas especially in aged dogs can present a diagnostic dilemma and distinction from MF and non-epidermotropic cutaneous lymphoma (NECL) is difficult on purely morphological grounds. A histiocytoma in the dog is a benign tumor. It is an abnormal growth in the skin of histiocytes (histiocytosis), a cell that is part of the immune system. A similar disease in humans, Hashimoto-Pritzker disease, is also a Langerhans cell histiocytosis.  As readers of the Dermatology Diary learned in the entry for week 3, a histiocytoma is a benign skin tumor, usually seen in young dogs, that often spontaneously regresses without treatment.. This is often alarming to dog owners; as it they often appear suddenly, almost overnight. Histiocytomas are not painful, and most dogs do not even seem to notice them, despite the fact that they lump may be ulcerated. Click here to view photos of a histiocytoma in a young dog. A histiocytoma is a benign skin tumor that originates in the Langerhans cells, immune cells that function to provide protective immunity to the tissues that are in contact with the outer environment -- the nose, stomach, intestines and lungs, but mainly the skin's surface.  Malignant fibrous histiocytoma (MFH), a type of sarcoma, is a malignant neoplasm of uncertain origin that arises both in soft tissue and bone. It was first introduced in 1961 by Kauffman and Stout (Ref. 22) and controversy has plagued it since.  Histiocytoma in dogs is a benign cell growth that may be seen on the surface of the skin. The condition affects more often dogs under the age of 5. The skin growth is often mistaken for a cancerous tumor, so a proper diagnosis is required. The precise causes of histiocytoma in dogs are not known. The tumors occur when the skin cells develop rapidly and uncontrollably. The condition affects dogs that are younger, under the age of 5 and certain dog breeds are more likely to have histiocytoma: Malignant fibrous histiocytoma is a soft tissue sarcoma that usually occurs in the limbs, most commonly the legs, and may also occur in the abdomen. Learn about malignant fibrous histiocytoma and find information on how we support and care for children and teens with sarcoma before, during, and after treatment. The exact cause of malignant fibrous histiocytoma is not entirely understood, however, studies have indicated that genetics may play a role. In addition: 1  Scientists are looking into the role of an associated genetic abnormality on the short arm of chromosome 19 that may give rise to this disease. The histiocytoma is an unsightly but benign skin tumor that tends to arise on the skin of young dogs. While young dogs (under three years of age) are more likely to get these (especially on the face and extremities), they can happen to dogs of any age in just about any location. Technically, a histiocytoma is an abnormal proliferation of histiocytes in the skin. Histiocytes are cells that function as part of the immunological barrier against invaders that would attempt an “attack” o A malignant fibrous histiocytoma is a type of cancerous tumor that can start in either bone or, most often, in the soft tissues that connect, support or surround organs and other body parts. It’s a painless mass that most often turns up in the extremities, although it can occur anywhere in the body. The exact cause of malignant fibrous histiocytoma is not entirely understood, however, studies have indicated that genetics may play a role. In addition: 1  Scientists are looking into the role of an associated genetic abnormality on the short arm of chromosome 19 that may give rise to this disease. Malignant fibrous histiocytoma is a condition involving a tumor of the bone or soft tissues. Malignant fibrous histiocytoma is a rare condition in which there is a tumor of the bone or soft tissues. The disease is the most common soft tissue cancer that is diagnosed in older adults, and is often diagnosed in people between the ages of 50 and 70. No one knows the exact cause or causes of malignant fibrous histiocytoma; however, research has shown that people with certain risk factors are more likely than others to develop the condition. A risk factor is anything that increases a person's chances of developing a disease.
http://www.histiocytosis.ucdavis.edu/histiocytoma.html https://en.wikipedia.org/wiki/Histiocytoma_(dog) http://vetmedicine.about.com/od/diseasesconditionsfaqs/f/FAQ_histiocytom.htm http://www.petmd.com/dog/conditions/skin/c_dg_histiocytoma http://www.sarcomahelp.org/mfh.html http://www.vetinfo.com/histiocytoma-in-dogs.html http://www.dana-farber.org/Pediatric-Care/Treatment-and-Support/Malignant-Fibrous-Histiocytoma.aspx http://www.embracepetinsurance.com/health/histiocytoma http://www.dana-farber.org/Pediatric-Care/Treatment-and-Support/Malignant-Fibrous-Histiocytoma.aspx http://bone-cancer.emedtv.com/malignant-fibrous-histiocytoma/malignant-fibrous-histiocytoma.html
what is histiocytoma