It is caused by either excessive cortisol-like medication such as prednisone or a tumor that either produces, or results in the production of excessive cortisol by the adrenal glands. Cushing's disease is a cause of Cushing's syndrome characterised by increased secretion of adrenocorticotropic hormone (ACTH) from the anterior pituitary (secondary hypercortisolism).
Cushing's syndrome, also known as hypercortisolism, Itsenko-Cushing syndrome, and hyperadrenocorticism, is a collection of signs and symptoms due to prolonged exposure to cortisol. Cases due to a pituitary adenoma are known as Cushing's disease. It is the second most common cause of Cushing's syndrome after medication. A number of other tumors may also cause Cushing's. *Cushing's syndrome facts by John P. Cunha, DO, FACOE. 1  Cushing's syndrome, or hypercortisolism, is a relatively rare hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. 1 It may also develop because of overproduction of cortisol by the body, or adrenal tumors. 2  Cushing's syndrome is diagnosed with tests such as the 24-hour urinary free cortisol level test, the dexamethasone suppression test, the CRH stimulation test, CT scan or MRI, and the dexamethasone-CRH test. 26. Cushing's syndrome is caused by too high a level of glucocorticoid in the body. This can be caused by taking steroid medication long-term (the common cause) or by the body making too much cortisol (the main glucocorticoid made by the body). Cushing's syndrome, caused by the body making too much cortisol, is rare. About 5 in 1 million people develop this type of Cushing's syndrome each year. Most cases are in people aged between 20 and 50. Women are five times more commonly affected than men. Cushing’s Syndrome is a disease caused by an excess of cortisol production or by excessive use of cortisol or other similar steroid (glucocorticoid) hormones. Cortisol is a normal hormone produced in the outer portion, or cortex, of the adrenal glands, located above each kidney.  1 Symptoms include upper body obesity, rounded face, increased fat around the neck, thinning arms and legs, fatigue, weakness, high blood pressure, and mood disorders. 2  Children tend to be obese with slowed growth rates. 3  Pituitary adenomas cause most cases of Cushing's syndrome. 1 It may also develop because of overproduction of cortisol by the body, or adrenal tumors. 2  Cushing's syndrome is diagnosed with tests such as the 24-hour urinary free cortisol level test, the dexamethasone suppression test, the CRH stimulation test, CT scan or MRI, and the dexamethasone-CRH test. Cushing's disease (also known as Cushing disease, tertiary or secondary hypercortisolism, tertiary or secondary hypercorticism, Itsenko-Cushing disease) is a cause of Cushing's syndrome characterised by increased secretion of adrenocorticotropic hormone (ACTH) from the anterior pituitary (secondary hypercortisolism).  Cushing’s disease is a specific type of Cushing’s syndrome caused by a pituitary tumor leading to excessive production of ACTH (Adrenocorticotropic hormone). Excessive ACTH stimulates the adrenal cortex to produce high levels of cortisol, producing the disease state. Cases due to a pituitary adenoma are known as Cushing's disease. It is the second most common cause of Cushing's syndrome after medication. A number of other tumors may also cause Cushing's. Causes. You can get Cushing's syndrome when there’s too much cortisol in your body for too long. Cortisol comes from your adrenal glands, which sit on top of your kidneys. The most common cause is related to medications called glucocorticoids, also commonly known as steroids or prednisone. The excess cortisol can throw your body's other systems off. Most cases of Cushing's syndrome can be cured, though it may take some time for your symptoms to ease up. The condition, also known as hypercortisolism, is more common in women than men. 1 Cushing's syndrome, or hypercortisolism, is a relatively rare hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. 1 It may also develop because of overproduction of cortisol by the body, or adrenal tumors. 2  Cushing's syndrome is diagnosed with tests such as the 24-hour urinary free cortisol level test, the dexamethasone suppression test, the CRH stimulation test, CT scan or MRI, and the dexamethasone-CRH test. Cushing's syndrome is caused by either excessive cortisol-like medication such as prednisone or a tumor that either produces, or results in the production of excessive cortisol by the adrenal glands. Cases due to a pituitary adenoma are known as Cushing's disease. It is the second most common cause of Cushing's syndrome after medication. A number of other tumors may also cause Cushing's.
https://en.wikipedia.org/wiki/Cushing%27s_syndrome http://www.medicinenet.com/cushings_syndrome/article.htm http://patient.info/health/cushings-syndrome-leaflet http://www.nadf.us/adrenal-diseases/cushings-syndrome/ http://www.medicinenet.com/cushings_syndrome/article.htm https://en.wikipedia.org/wiki/Cushing%27s_disease https://en.wikipedia.org/wiki/Cushing%27s_syndrome http://www.webmd.com/a-to-z-guides/cushing-syndrome http://www.medicinenet.com/cushings_syndrome/article.htm https://en.wikipedia.org/wiki/Cushing%27s_syndrome
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