localized
The symptoms and treatment for rheumatoid arthritis (RA) and osteoarthritis are different, and an accurate diagnosis is important for the patient's health. RA is an autoimmune disease where the immune system attacks healthy tissues in the body. Along the same lines, it is highly unlikely that patients with localized scleroderma progress and develop severe systemic (internal) conditions such as rheumatoid arthritis, or lupus erythematosus, or systemic sclerosis (the internal form of scleroderma). Osteoarthritis is a disease of the joints. Unlike many other forms of arthritis, such as rheumatoid arthritis and systemic lupus, osteoarthritis does not affect other organs of the body. The most common symptom of osteoarthritis is pain in the affected joints after repetitive use. Joint pain is usually worse later in the day. Osteoarthritis (OA) is a disease of the entire joint involving the cartilage, joint lining, ligaments, and underlying bone. The breakdown of these tissues eventually leads to pain and joint stiffness. The joints most commonly affected are the knees, hips, and those in the hands and spine. The Dangers of Osteoarthritis. Unlike rheumatoid arthritis, which is characterized by systemic inflammation, osteoarthritis is a localized disease that occurs only in the affected joints. With osteoarthritis, the thin layer of cartilage between the joints gradually erodes and wears away. Joint symptoms. Joints painful but without swelling; affects joints asymmetrically; affects bigger joints such as hips & knees. Localized with variable, progressive course. Joints are painful, swollen, and stiff; affects joints symmetrically; affects smaller joints such as hands & ankles. Systemic with exacerbations and remissions.
http://www.diffen.com/difference/Osteoarthritis_vs_Rheumatoid_Arthritis http://www.scleroderma.org/site/DocServer/Localized.pdf?docID=317 http://www.webmd.com/osteoarthritis/default.htm http://www.cdc.gov/arthritis/basics/osteoarthritis.htm https://www.drvitaminsolutions.com/content/osteoarthritis-01 http://www.diffen.com/difference/Osteoarthritis_vs_Rheumatoid_Arthritis
is osteoarthritis localized or systemic