They are transcribed in the nucleus but are then translated in the cell's cytoplasm.
In a multicellular organism every cell contains every gene found in the organism. Not all genes are actually used in every cell. The specialization of cell into different types means that some genes are used in some cells and not in others.  Often, for gene transcription to occur, a number of transcription factors must bind to DNA regulatory sequences. This collection of transcription factors, in turn, recruit intermediary proteins such as cofactors that allow efficient recruitment of the preinitiation complex and RNA polymerase. Thus, for a single transcription factor to initiate transcription, all of these other proteins must also be present, and the transcription factor must be in a state where it can bind to them if necessary. Cofactors are proteins that modulate the effects of transcription factors. Transcription factors perform this function alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription of genetic information from DNA to RNA) to specific genes. Thus, for a single transcription factor to initiate transcription, all of these other proteins must also be present, and the transcription factor must be in a state where it can bind to them if necessary. Cofactors are proteins that modulate the effects of transcription factors. A eukaryotic cell has a nucleus that separates the processes of transcription and translation. Eukaryotic transcription occurs within the nucleus where DNA is packaged into nucleosomes and higher order chromatin structures. When transcription is arrested by the presence of a lesion in the transcribed strand of a gene, DNA repair proteins are recruited to the stalled RNA polymerase to initiate a process called transcription-coupled repair. Central to this process is the general transcription factor TFIIH that has ATPase activity In eukaryotes, transcription factors (like most proteins) are transcribed in the nucleus but are then translated in the cell's cytoplasm. Many proteins that are active in the nucleus contain nuclear localization signals that direct them to the nucleus. Thus, for a single transcription factor to initiate transcription, all of these other proteins must also be present, and the transcription factor must be in a state where it can bind to them if necessary. Cofactors are proteins that modulate the effects of transcription factors. Report Abuse. Transcription factors are protein complexes that help RNA polymerase bind to DNA. RNA polymerase is the enzyme that transcribes genes to make messenger RNA, which is then used to make protein. By controlling RNA polymerase's access to the gene, transcription factors control the rate at which a gene is transcribed. Without transcription factors, cells would not be able to effectively regulate the rate at which genes are expressed. What is the function of transcription factors in eukaryotic cells? A. They control the expression of certain genes. B. They bend the DNA to bring it close to the operator. Gene transcription occurs in both eukaryotic and prokaryotic cells.Unlike prokaryotic RNA polymerase that initiates the transcription of all different types of RNA, RNA polymerase in eukaryotes (including humans) comes in three variations, each encoding a different type of gene. When transcription is arrested by the presence of a lesion in the transcribed strand of a gene, DNA repair proteins are recruited to the stalled RNA polymerase to initiate a process called transcription-coupled repair. Central to this process is the general transcription factor TFIIH that has ATPase activity Transcription is the process of copying genetic information stored in a DNA strand into a transportable complementary strand of RNA. Eukaryotic transcription takes place in the nucleus of the cell and proceeds in three sequential stages: initiation, elongation, and termination. When transcription is arrested by the presence of a lesion in the transcribed strand of a gene, DNA repair proteins are recruited to the stalled RNA polymerase to initiate a process called transcription-coupled repair. Central to this process is the general transcription factor TFIIH that has ATPase activity Transcription factors are one of the groups of proteins that read and interpret the genetic blueprint in the DNA. They bind to the DNA and help initiate a program of increased or decreased gene transcription. As such, they are vital for many important cellular processes. Thus, for a single transcription factor to initiate transcription, all of these other proteins must also be present, and the transcription factor must be in a state where it can bind to them if necessary. Cofactors are proteins that modulate the effects of transcription factors.
http://highered.mheducation.com/sites/9834092339/student_view0/chapter15/transcription_factors.html https://en.wikipedia.org/wiki/Transcription_factor https://en.wikipedia.org/wiki/Transcription_factor https://en.wikipedia.org/wiki/Eukaryotic_transcription https://en.wikipedia.org/wiki/Transcription_factor https://answers.yahoo.com/question/index?qid=20081112105452AAjb4Df https://en.wikipedia.org/wiki/Eukaryotic_transcription https://en.wikipedia.org/wiki/Eukaryotic_transcription https://en.wikipedia.org/wiki/Transcription_factor
what do transcription factors do in eukaryotic cells