It is a type of systemic scleroderma and an ongoing, progressive, autoimmune disease that attacks the connective tissues of the body.
Definition. Limited scleroderma, or CREST syndrome, is one subtype of scleroderma — a condition that literally means hardened skin.. The skin changes associated with limited scleroderma typically occur only in the lower arms and legs and sometimes the face and throat. Limited scleroderma can also affect your digestive tract.  CREST Syndrome is a form of scleroderma that is characterized by least two of the following symptoms: calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia. Common symptoms reported by people with CREST Syndrome.  CREST syndrome: Introduction. CREST syndrome is a type of systemic scleroderma and an ongoing, progressive, autoimmune disease that attacks the connective tissues of the body. CREST syndrome can also affect any part of the body. CREST is an acronym for a group of conditions that are hallmarks of CREST syndrome and affect the skin, muscles, digestive tract and other organs and blood vessels. The exact cause of CREST syndrome is not known, but it is classified as an autoimmune disease. CREST syndrome is a disease of skin and blood vessels and, in severe cases, the lungs, digestive tract, or heart. To be diagnosed with CREST, an individual must display at least two of the five symptoms. It is often associated with scleroderma.  CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc) is a multisystem connective tissue disorder. The acronym CREST refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. CREST syndrome. [krest]. abbreviation for c alcinosis, R aynaud's phenomenon, e sophageal dysfunction, s clerodactyly, and t elangiectasis. CREST syndrome is a disease of skin and blood vessels and, in severe cases, the lungs, digestive tract, or heart. To be diagnosed with CREST, an individual must display at least two of the five symptoms.  CREST syndrome is a type of systemic scleroderma and an ongoing, progressive, autoimmune disease that attacks the connective tissues of ... more 1  ». CREST syndrome: Group of symptoms usually related to systemic sclerosis. 2  CREST syndrome: A mild form of LIMITED SCLERODERMA, a multi-system disorder. 1 CREST syndrome: A mild form of LIMITED SCLERODERMA, a multi-system disorder. 2  Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. 3  When the defect in esophageal function is not prominent, it is known as CRST syndrome. In this article. Some people have a type of scleroderma called CREST syndrome (or limited scleroderma). Unlike other types, which only affect the arms, legs, and face, this kind can involve your digestive tract. While less common, it can also lead to problems with your heart and lungs.  CREST syndrome: A limited form of scleroderma, a disease of connective tissue that involves the formation of scar tissue (fibrosis) in the skin and sometimes also in other organs of the body. 
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what is crest disease