It is usually a sign of bone marrow stress as well as immature red blood cells.
Answered by The Community. Making the world better, one answer at a time. polychromasia: the reaction of red cells to stain as indicated by the appearance of bluish or grayish colored erythrocytes Polychromasia refers to variation in erythrocyte coloration. This variation largely relates to the maturation of the cell. Increases in polychromasia suggest an increased bone marrow response. No polychromasia correlates with non-responsive, anemic patients, which is characterized by all cells exhibiting the same coloration. This finding presents a guarded prognosis, pending resolution of the cause of the non-regeneration. Polychromasia is usually a sign of bone marrow stress as well as immature red blood cells. 3 types are recognized, with types (1) and (2) being referred to as 'young red blood cells' and type (3) as 'old red blood cells'. Giemsa stain is used to distinguish all three types in blood smears. The formation of red blood cells is commonly known as haematopoiesis. Up to the first 60 days of life, the yolk sac is the main source of haematopoiesis. The liver is then used as the main hematopoietic organ of the embryo until near birth, where it is then taken over by the bone marrow. Increases in polychromasia suggest an increased bone marrow response. No polychromasia correlates with non-responsive, anemic patients, which is characterized by all cells exhibiting the same coloration. This finding presents a guarded prognosis, pending resolution of the cause of the non-regeneration. Erythrocytic Anisocytosis Mature avian erythrocytes are oval-shaped and nucleated POLYCHROMASIA. Polychromasia is a variation in staining of erythrocytes with the Wright's stain because of the presence of young erythrocytes. These young cells have a diffuse bluish color, blue color, indicating residual RNA. They will appear as reticulocytes with methylene blue staining. An increase in the number of polychromatophilic erythrocytes or reticulocytes indicates accelerated erythropoiesis and a response to an anemia. Polychromasia occurs when the immature reticulocytes of the bone marrow are released, resulting in a grayish blue color of the cells. This color is seen because of the ribosomes still left on the immature blood cells, which are not found on mature red blood cells. The formation of red blood cells is commonly known as haematopoiesis. Up to the first 60 days of life, the yolk sac is the main source of haematopoiesis. The liver is then used as the main hematopoietic organ of the embryo until near birth, where it is then taken over by the bone marrow. Get help from a doctor now ›. Part of anemia: Polychromasia means lots of immature red blood cells in the blood stream. When red blood cells don't have enough nutrients they can be smaller (microcyte) or bigger (macrocyte) than usual. Microcytes + anemia is usually due to iron deficiency.  pol·y·chro·ma·to·phil·i·a. 1. A tendency of certain cells, such as the red blood cells in pernicious anemia, to stain with basic and also acidic dyes. 2. Condition characterized by the presence of many red blood cells that have an affinity for acid, basic, or neutral stains. Synonym(s): polychromasia.  Shares & Saves. Save. Polychromasia refers to a condition in which red blood cells (RBCs) appear grayish-blue in color when examined on a blood smear slide under a microscope. Polychromasia occurs when RBCs are released prematurely from the bone marrow, where they are produced. RBCs are released prematurely in response to a certain type of hormone stimulation usually resulting from anemia or possibly due to structural damage to the bone marrow from a variety of causes.
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what is polychromasia