10.5826/dpc.1201a04
text/xml
2160-9381
1684
en
Server Serdaroglu
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
Scrotal Basal Cell Carcinoma—A Rare Manifestation
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-02-02
2021-02-23
2022-02-02
2022-02-09
e2022004
Dermatol Pract Concept
Server Serdaroglu
2022/02/02
10.5826/dpc.1201a04
e2022004
Istanbul University, Cerrahpasa, Cerrahpasa Medical Faculty Department of Dermatology, Istanbul, Turkey
2160-9381
en
e2022004
Dai B, Kong YY, Ye DW, Xu XW, Yao XD, Zhang SL. Basal cell carcinoma of the scrotum: clinicopathologic analysis of 10 cases. Dermatol Surg. 2012;38(5):783-790. DOI: 10.1111/j.1524-4725.2012.02356.x. PMID: 22309181.
Scrotal Basal Cell Carcinoma—A Rare Manifestation
https://dpcj.org/index.php/dpc/article/download/1684/1482
                   Scrotal Basal Cell Carcinoma—A Rare
                               Manifestation
Tugba Kevser Uzuncakmak1, Defne Özkoca1, Bengu Cobanoglu Simsek2, Server Serdaroğlu1


1 Istanbul University, Cerrahpasa, Cerrahpasa Medical Faculty Department of Dermatology, Istanbul, Turkey
2 Istanbul Medeniyet University Medical Faculty, Department of Pathology, Istanbul, Turkey



Citation: Uzuncakmak TK, Özkoca D, Simsek BC, Serdanoğlu S. Scrotal basal cell carcinoma – a rare manifestation. Dermatol Pract
Concept. 2022;12(1):e2022004. DOI: https://doi.org/10.5826/dpc.1201a04
Accepted: April 13, 2021; Published: January 2022
Copyright: ©2022 Uzuncakmak et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-
NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication
Corresponding author: Tugba Kevser Uzuncakmak, MD, Istanbul University Cerrahpasa Medical Faculty, Department of Dermatology,
Istanbul, Turkey. E-mail: drtugbakevser@gmail.com




Case Presentation                                                       was referred for total excision. The histopathology revealed
                                                                        basal cell cancer of metatypical type (Figure 1D). No new
A 68-year-old male presented with a 6-year history of a                 lesions were observed in the biannual follow-up visit.
slowly growing ulcerated lesion on the scrotum. Dermato-
logical examination revealed a polypoid lesion of 2 × 2 cm
                                                                        Teaching Point
on an erythematous base on the left scrotum. The surface was
ulcerated, and microbleeding spots were observed ­(Figure 1,            Basal cell carcinoma is the most common type of cancer that
A and B). No other lesions were present. Contact dermos-                is commonly seen on sun-exposed areas, yet it is rarely seen
copy of the lesion revealed polymorphic linearly grouped                on the genitalia. Despite its rarity, genital basal cell carci-
dotted vessels and short linear vessels. Surface ulceration             nomas have increased risk of distant metastasis. Therefore,
was prominent with the rope sign. Crystallite structures were           after the initial therapy, long-term follow-up is mandatory
evident in the left lower quadrant. (Figure 1C). The patient            in these cases.




Image Letter | Dermatol Pract Concept. 2022;12(1):e2022004                                                                           1
Figure 1. (A and B) A 2 × 2 cm sized, polypoid, centrally ulcerated tumoral lesion on an erythematous base on the left scrotum. (C) Poly-
morphic linearly grouped dotted vessels and short linear vessels. Surface ulceration was prominent with the rope sign. (D) Widespread
ulceration on the surface. Tumor cells proliferating as nodular structures from the basal layer to the stroma had pale large cytoplasm
(H&E, ×100).




References                                                             2. Dai B, Kong YY, Ye DW, Xu XW, Yao XD, Zhang SL. Basal cell
                                                                          carcinoma of the scrotum: clinicopathologic analysis of 10 cases.
1. Han S, Zhang Y, Tian R, Guo K. Basal cell carcinoma aris-              Dermatol Surg. 2012;38(5):783-790. DOI: 10.1111/j.1524-
   ing from the scrotum: an understated entity. Urol Case Rep.            4725.2012.02356.x. PMID: 22309181.
   2020;33:101332. DOI: 10.1016/j.eucr.2020.101332. PMID:
   33102034; PMCID: PMC7573964.




2                                                                            Image Letter | Dermatol Pract Concept. 2022;12(1):e2022004
