10.5826/dpc.1204a149
text/xml
2160-9381
2055
en
Alejandro  Martínez-García
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
Aneurysmal dermatofibroma after varicose vein surgery.
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-10-31
2021-09-20
2022-10-31
2022-11-29
e2022149
Dermatol Pract Concept
Alejandro  Martínez-García
2022/10/31
10.5826/dpc.1204a149
e2022149
Pathology Service, Lozano Blesa University Hospital, Zaragoza, Spain. 
2160-9381
en
e2022149
Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J, Puig S. Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients. Br J Dermatol. 2006 Feb;154(2):244-50. doi: 10.1111/j.1365-2133.2005.06844.x. PMID: 16433792.
Aneurysmal dermatofibroma after varicose vein surgery.
https://dpcj.org/index.php/dpc/article/download/2055/1800
           Aneurysmal Dermatofibroma After Varicose
                        Vein Surgery
                 Pablo Villagrasa-Boli1, Juan Monte-Serrano1, Sara Martínez-Cisneros1,
                                      Alejandro Martínez-García2


1 Dermatology Service, Lozano Blesa University Hospital, Zaragoza, Spain
2 Pathology Service, Lozano Blesa University Hospital, Zaragoza, Spain



Citation: Villagrasa-Boli P, Monte-Serrano J, Martínez-Cisneros S, Martínez-García A. Aneurysmal dermatofibroma after varicose vein
surgery. Dermatol Pract Concept. 2022;12(4):e2022149. DOI: https://doi.org/10.5826/dpc.1204a149
Accepted: January 15, 2022; Published: October 2022
Copyright: ©2022 Villagrasa-Boli et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-
NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Pablo Villagrasa Boli, Dermatology Service, Lozano Blesa University Hospital. San Juan Bosco Avenue, 15, 50009,
Zaragoza, Spain. E-mail: pablovillaboli@gmail.com




Case presentation                                                        stroma containing spindle cells (Figure 1C). Immunohisto-
                                                                         chemical tinctions for Factor XIIIa (Figure 1D) and for CD68
A 45-year-old man was referred to dermatology consulta-                  were positive, while human herpesvirus 8 was not detected.
tions for evaluation of a pigmented lesion on the left leg. The
lesion appeared at the incision site of a varicose vein surgery
                                                                         Teaching point
performed one year prior.
    Clinical examination revealed an indurated 12 mm brown               Aneurysmatic dermatofibroma represents approximately
plaque (Figure 1A). Dermoscopy showed at the center white                1.7% of all types of dermatofibromas [1]. Like any derma-
network surrounded by bluish areas and a rainbow pattern,                tofibroma, this subtype may appear after local trauma. Its
and at the periphery a homogeneous brown color (Figure 1B).              clinical diagnosis can be difficult due to its resemblance to
Histopathological examination revealed blood-filled spaces               malignant tumors, such as Kaposi sarcoma, angiomatoid
with peripheral hemosiderin deposits, and a dense collagenous            malignant fibrous histiocytoma and melanoma [2].




Image Letter | Dermatol Pract Concept. 2022;12(4):e2022149                                                                                1
Figure 1. (A) Clinical examination of the lower limbs. The hematoma on the right leg is unrelated to the reason for consultation.
(B) Multi-component dermoscopic pattern composed of central white stripes with rainbow areas, and a peripheral brown network.
(C) Dense tumoral stroma with congested blood vessels; the epidermis shows basal layer hyperpigmentation, acanthosis and hyperkerato-
sis. (D) diffuse positivity for factor XIIIa throughout the tumor.



References                                                            2. Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J,
                                                                         Puig S. Dermoscopic findings of haemosiderotic and aneurys-
1. Güngör Ş, Erdemir AT, Öztürk Sarı Ş, Büyükbabani N, K
                                                       ­ ocatürk E,      mal dermatofibroma: report of six patients. Br J Dermatol.
   Gürel MS. Aneurysmatic dermatofibroma with dermoscopic and            2006;154(2):244-250. DOI: 10.1111/j.1365-2133.2005.06844.x.
   reflectance confocal microscopic features. J Eur Acad ­Dermatol       PMID: 16433792.
   Venereol. 2016;30(5):880-883. DOI: 10.1111/jdv.13046. PMID:
   25690844.




2                                                                          Image Letter | Dermatol Pract Concept. 2022;12(4):e2022149
