10.5826/dpc.1301a28
text/xml
2160-9381
2409
en
Meenakshi Sachdeva
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
pink
Various Color Presentations of Pseudochromhidrosis—A Case Series
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Research Letter
2023-01-31
2022-02-18
2023-01-31
2023-02-27
e2023028
Dermatol Pract Concept
Meenakshi Sachdeva
2023/01/31
10.5826/dpc.1301a28
e2023028
Department of Dermatology, Venereology and Leprosy, Pt B.D. Sharma, University of Health Sciences, Rohtak, Haryana, India
2160-9381
pink
en
e2023028
Singal A, Thami GP. Red pseudochromhidrosis of the neck. Clin Exp Dermatol. 2004;29(5):548-549. DOI: 10.1111/j.1365-2230.2004.01567.x. PMID: 15347348.
Various Color Presentations of Pseudochromhidrosis—A Case Series
https://dpcj.org/index.php/dpc/article/download/2409/1913
                      Various Colors of Presentation
                 of Pseudochromhidrosis - A Case Series
         Priyadarshini Sahu1, Disha Chakraborty1, Surabhi Dayal1, Meenakshi Sachdeva1


1 Department of Dermatology, Venereology and Leprosy, Pt B.D. Sharma, University of Health Sciences, Rohtak, Haryana, India



Key words: pseudochromhidrosis, red, black, pink
Citation: Sahu P, Chakraborty D, Dayal S, Sachdeva M. Various Colors of Presentation of Pseudochromhidrosis - A Case Series.
Dermatol Pract Concept. 2023;13(1):e2023028. DOI: https://doi.org/10.5826/dpc.1301a28
Accepted: June 8, 2022; Published: January 2023
Copyright: ©2023 Sahu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-
NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing Interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding Author: Priyadarshini Sahu, Department of Dermatology, Venereology and Leprosy, Pt. B. D. Sharma, University of Health
Sciences, Rohtak, Haryana, India. Pin-124001 Tel: +91-9416536159 E-mail: priyadarshini.sahu.9@gmail.com




Introduction                                                                  Case 2. A 7-year-old boy presented with progressive
                                                                         darkening of both the palms since last 5 days. Skin bi-
Colored sweat is a sporadic disorder, which can be due to                opsy was performed which supported the diagnosis of
apocrine, true eccrine and pseudo-ecrrine chromhidrosis [1].             pseudo-chromhidrosis.
Pseudo-chromhidrosis is characterized by excretion of nor-                    Case 3. A 36-year-old female, known case of rheuma-
mal colorless sweat, which becomes colored following contact             toid arthritis presented with 10 days history of pink dis-
with products of chromogenic microbial or extrinsic chem-                coloration of both palms which aggravated with exertion.
icals on the skin surface [2]. There are very few case reports           She did not give consent for biopsy. Clinical diagnosis of
of pseudo-chromhidrosis [1-4]. Hereby, we present three                  pseudo-chromhidrosis was made.
sporadic case of red, black and pink pseudo-chromhidrosis.                    In all the three cases, color fade on rubbing with ab-
                                                                         solute alcohol. All patients denied intake of food, vitamin

Case Presentation                                                        supplements, use of cosmetics or dyes that could have
                                                                         caused such discoloration. There was no specific odor or
Case 1. An apparently healthy 10-year-old female presented               bleeding from any site. Psychological assessment was nor-
with reddish discoloration of both palms for last 7 days. Her            mal and family history was insignificant for all patients.
brother was also suffering from the similar complaint. Clinical          Routine biochemical tests, gram staining, fungal scrapping
examination revealed palmar creases with reddish secretion               and staining revealed no abnormality. All patients were
(Figure 1). Skin biopsy was negative for lipofuscin granules             prescribed oral erythromycin and topical clindamycin
around eccrine orifices which ruled out apocrine chromhidro-             which resulted in complete relief with no recurrence for
sis. Clinical diagnosis of pseudo-chromhidrosis was made.                all patients.




Research Letter | Dermatol Pract Concept. 2023;13(1):e2023028                                                                          1
Figure 1. Pre-treatment and post-treatment photographs of patients of red pseudo-chromhidrosis.




Figure 2. Pre-treatment and post-treatment photographs of patients of pink pseudo-chromhidrosis.



Conclusions                                                          as there is difference in management with different types.
                                                                     Pseudo-chromhidrosis can be treated with topical or systemic
Chromhidrosis, ie colored sweat can be produced by eccrine           antibiotics and cessation of offending agents.
and apocrine glands. Eccrine chromhidrosis due to intrinsic              Although, pseudo-chromhidrosis does not constitute
factors is known as true eccrine chromhidrosis and second-           a health issue, it may cause psychological stress and social
ary to extrinsic factors is known as pseudo-chromhidrosis.           embarrassment. Thus, dermatologist must be aware of the
In pseudo-chromhidrosis, sweat produced is colorless but it          various colors of chromhidrosis in order to determine its ac-
becomes colored because of chromogen, which include chro-            tual cause as pseudo-chromhidrosis is easily treatable with
mogenic bacteria, chemicals, paints, dyes and self-tanning           antiseptic scrub, topical, systemic antibiotics [2]. On detail
products [2].                                                        literature scan, red pseudo-chromhidrosis has never been
    Apocrine chromhidrosis is due to presence of increased           reported on palms and pink pseudo-chromhidrois has been
amount of lipofuscin granules in apocrine glands and their           once been reported in the literature.
excretion in sweat produces colored sweat [5]. While the di-
agnosis of eccrine chromhidrosis depends on detailed patient
history and exclusion of ingestion of pigments, diagnosis of         References
pseudo-chromhidrosis is based on exclusion of chromhidrosis
                                                                      1. Nair PA, Kota RK, Surti NK, Diwan NG, Gandhi SS. Yellow
and successful treatment with antibiotics or antiseptic scrub            pseudochromhidrosis in a young female. Indian Dermatol On-
in this case. Thus, it is very important to distinguish between          line J. 2017;8(1):42-44. DOI: 10.4103/2229-5178.198778.
apocrine or eccrine chromhidrosis and pseudo-chromhidrosis               PMID: 28217472. PMCID: PMC5297270.



2                                                                         Research Letter | Dermatol Pract Concept. 2023;13(1):e2023028
 2. Koley S, Mandal RK. Red and black pseudochromhidrosis. In-   4. Mapare A, Tapre V, Khandelwal A. Apocrine chromhidrosis
    dian J Dermatol. 2016;61(4):454-457. DOI: 10.4103/0019          over dorsum of foot. Journal of Dental and Medical Sciences.
    -5154.185733. PMID: 27512200. PMCID: PMC4966413.                2012;2(3):33-34.
 3. LeFeber WP, Golitz LE. Green foot.      Pediatr Dermatol.    5. Singal A, Thami GP. Red pseudochromhidrosis of the neck.
    1984;2(1):38-40. DOI: 10.1111/j.1525-1470.1984.tb00439.x.       Clin Exp Dermatol. 2004;29(5):548-549. DOI: 10.1111/j.1365
    PMID: 6438617.                                                  -2230.2004.01567.x. PMID: 15347348.




Research Letter | Dermatol Pract Concept. 2023;13(1):e2023028                                                                 3
