10.5826/dpc.1201a43
text/xml
2160-9381
1855
en
Francisco Javier Salazar-Torres
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
Combined Epidermal-Follicular Mucinous Nevus: Dermoscopic Appearance 
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-02-02
2021-06-28
2022-02-02
2022-02-09
e2022043
Dermatol Pract Concept
Francisco Javier Salazar-Torres
2022/02/02
10.5826/dpc.1201a43
e2022043
Dermatology Institute of Jalisco, “Dr. José Barba Rubio”, Zapopan, México
2160-9381
en
e2022043
Oiso N, Kimura M, Kawada A. Follicular mucinous nevus: a possible new variant of mucinous nevus. J Am Acad Dermatol. 2014;71(4):e141-e1422. DOI: 10.1016/j.jaad.2014.04.065. PMID: 25219735.
Combined Epidermal-Follicular Mucinous Nevus: Dermoscopic Appearance 
https://dpcj.org/index.php/dpc/article/download/1855/1493
     Combined Epidermal-Follicular Mucinous Nevus:
               Dermoscopic Appearance
                             Arturo Robles-Tenorio1, Francisco Javier Salazar-Torres1


1 Dermatology Institute of Jalisco, “Dr. José Barba Rubio”, Zapopan, México



Citation: Robles-Tenorio A, Salazar-Torres FJ. Combined epidermal-follicular mucinous nevus: dermoscopic appearance.
Dermatol Pract Concept. 2022;12(1):e2022043. DOI: https://doi.org/10.5826/dpc.1201a43
Accepted: July 17, 2021; Published: January 2022
Copyright: ©2022 Robles-Tenorio and Salazar-Torres. This is an open-access article distributed under the terms of the Creative
Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted
noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Robles-Tenorio, MD, MSc, Dermatology Institute of Jalisco, “Dr. José Barba Rubio”, Zapopan, México.
E-mail: arturo.robten@gmail.com




Case Presentation                                                        and geometric brown structures were observed on der-
                                                                         moscopy (Figure 1B). Epidermal hyperkeratosis, acantho-
A 17-year-old Hispanic male presented with long-standing                 sis, papillomatosis, as well as abundant mucin deposits
asymptomatic papules grouped as an irregular, brown,                     around the hair follicles were noted on histopathology,
10 cm × 6 cm × 0.2 cm plaque over the right aspect of                    compatible with combined epidermal-follicular mucinous
the neck (Figure 1A). Perifollicular hypopigmentation                    nevus (MN).




                  Figure 1. Combined epidermal-follicular mucinous nevus. (A) Clinical appearance. (B) Perifollicular hy-
                  popigmentation and pigmented geometric structures around the papules can be observed on dermoscopy.


Image Letter | Dermatol Pract Concept. 2022;12(1):e2022043                                                                           1
Teaching Point                                                     Informed consent: Informed consent for publication of clini-
                                                                   cal details and clinical images was obtained from the patient.
There are less than 30 reports of MN in the literature [1].
Histopathology is essential for the diagnosis, wherein mucin
deposits along the superficial dermis are present. The combined
                                                                   References
epidermal subtype also exhibits hyperkeratosis, acanthosis, and    1. Lepage W, Frouin É, Junca A, et al. Mucinous nevus of late onset.
rete ridges elongation. Perifollicular mucinous involvement has       Ann Dermatol Venereol. 2016;143(8):547-553. DOI: 10.1016/
only been described in one case, yet epidermal changes were           j.annder.2016.03.017. PMID: 27197785.
                                                                   2. Oiso N, Kimura M, Kawada A. Follicular mucinous nevus: a
subtle [2]. In contrast, we observed epidermal changes and per-
                                                                      possible new variant of mucinous nevus. J Am Acad Dermatol.
ifollicular mucin deposits, which correlated with perifollicular
                                                                      2014;71(4):e141-e1422. DOI: 10.1016/j.jaad.2014.04.065.
hypopigmentation observed in dermoscopy. The dermoscopic              PMID: 25219735.
appearance of MN has not been previously documented.




2                                                                        Image Letter | Dermatol Pract Concept. 2022;12(1):e2022043
