10.5826/dpc.1203a96
text/xml
2160-9381
2074
en
Qiuning Sun
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
A Particular Bicentric Structure in Dermoscopy of Degos Disease
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-07-28
2021-09-26
2022-07-28
2022-09-15
e2022096
Dermatol Pract Concept
Qiuning Sun
2022/07/28
10.5826/dpc.1203a96
e2022096
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
2160-9381
en
e2022096
Dermatol Pract Concept. 2014;4(3):59-61. DOI: 10.5826/dpc.0403a11. PMID: 25126461. PMCID: PMC4132001.
A Particular Bicentric Structure in Dermoscopy of Degos Disease
https://dpcj.org/index.php/dpc/article/download/2074/1673
                    Dermatology Practical & Conceptual


      A Particular Bicentric Structure in Dermoscopic
             Demonstration of Degos Disease
                                          Anqi Li1, Rouyu Fang1, Qiuning Sun1


1 Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical
  College, Beijing, China



Citation: Li A, Fang R, Sun Q. A Particular bicentric structure in dermoscopic demonstration of Degos Disease.
Dermatol Pract Concept. 2022;12(3):e2022096. DOI: https://doi.org/10.5826/dpc.1203a96
Accepted: October 30, 2021; Published: July 2022
Copyright: ©2022 Li et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial
License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and
reproduction in any medium, provided the original authors and source are credited.
Funding: This research was supported by Sedimentation Integration Fund of Peking Union Medical College Hospital (ZC201902245).
Competing interests: None.
Authorship: All authors have contributed significantly to this publication
Corresponding author: Qiuning Sun, Peking Union Medical College Hospital, Department of Dermatology No.1 Shuaifuyuan, Dongcheng
District, Beijing, China. Tel: +86 13910318639, E-mail: doctorjenny1@126.com




Case Presentation                                                       2 yellow-white structureless centers of different sizes with
                                                                        telangiectasia, similar to a bicentric structure (Figure 1B).
A 38-year-old woman suffered recurrent abdominal pain                   Histopathology showed intravascular thrombosis in the der-
and rashes for 1 year. Physical examination showed multi-               mis (Figure 1C). Abdominal CT scanning confirmed small
ple red papules with porcelain-white centers over her trunk             bowel perforation and abdominal adhesion. A diagnosis of
and limbs (Figure 1A). Dermoscopic imaging demonstrated                 Degos disease was made.




Figure 1. Clinical, dermoscopic, and histopathological figures (A) red papules with porcelain-white atrophic centers (B) two yellow-white
structureless centers in different sizes with telangiectasia (C) epidermis atrophy, vacuolar degeneration of basal layer, increased collagen
fibers, and intravascular thrombosis of the dermis.



Image Letter | Dermatol Pract Concept. 2022;12(3):e2022096                                                                                1
Teaching point                                                    References
Degos disease is characterized by unusual chronic throm-          1. Darwich E, Guilabert A, Mascaró JM Jr, et al. Dermoscopic
                                                                     description of a patient with thrombocythemia and factor V
bo-obliterative vasculopathy that affects small vessels. The
                                                                     Leiden mutation-associated Degos’ disease. Int J Dermatol.
histopathology of Degos disease is inconsistent, so dermos-
                                                                     2011;50(5):604-6. DOI: 10.1111/j.1365-4632.2010.04539.x.
copy may be helpful in making a definite diagnosis. The              PMID: 21506980.
dermoscopic character of Degos disease is a homogeneous           2. Anker JP, Kaminska-Winciorek G, Lallas A, et al. The dermo-
yellow-white structureless area in the center, surrounded by         scopic variability of Degos disease at different stages of progres-
a circular hairpin-like small vessel [1,2]. Apart from the fea-      sion. Dermatol Pract Concept. 2014;4(3):59-61. DOI: 10.5826/
                                                                     dpc.0403a11. PMID: 25126461. PMCID: PMC4132001.
tures mentioned previously, we noticed a particular bicentric
structure, which is related to avascular necrosis caused by
thrombosis.




2                                                                       Image Letter | Dermatol Pract Concept. 2022;12(3):e2022096
