10.5826/dpc.1202a67
text/xml
2160-9381
1834
en
Miguel Dominguez-Santas
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
Intralympathic histiocytosis
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-05-02
2021-06-10
2022-05-02
2022-05-24
e2022067
Dermatol Pract Concept
Miguel Dominguez-Santas
2022/05/02
10.5826/dpc.1202a67
e2022067
Dermatology Department, Ramon y Cajal University Hospital, Madrid, Spain 
2160-9381
en
e2022067
Korman JB, Burgin S, Tahan SR. Intralymphatic histiocytosis in association with severe osteoarthritis of the shoulder. J Am Acad Dermatol. 2013;69(6):e314–e315. DOI: 10.1016/j.jaad.2013.08.020. PMID: 24238195.
Intralympathic histiocytosis
https://dpcj.org/index.php/dpc/article/download/1834/1566
                                Intralymphatic Histiocytosis
         Emilio Garcia-Mouronte1, Borja Diaz-Guimaraens1, Emilio de Dios Berna-Rico1,
                                  Miguel Dominguez-Santas1


1 Dermatology Department, Ramon y Cajal University Hospital, Madrid, Spain



Citation: Garcia-Mouronte E, Diaz-Guimaraens B, Berna-Rico E, Dominguez-Santas M. Intralymphatic histiocytosis.
Dermatol Pract Concept. 2022;12(2):e2022067. DOI: https://doi.org/10.5826/dpc.1202a67
Accepted: September 6, 2021; Published: April 2022
Copyright: ©2022 Iorizzo et al. This is an open-access article distributed under the terms of the Creative Commons
Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted
noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Emilio Garcia-Mouronte, MD. Dermatology Department, Ramon y Cajal University Hospital. Carretera Colmenar
Viejo km 9.100, 28034 Madrid, Spain. E-mail: emilio.garcia.mouronte@gmail.com




Case Presentation
An 87-year-old man presented to our Dermatology depart-
ment with a history of 1-year-long asymptomatic erythem-
atous plaques on his left shoulder. He referred he had been
previously diagnosed from severe osteoarthritis on this loca-
tion. Moreover, he denied taking regular medication, expo-
sure to heat or suffering from any other medical condition.
    Dermatological examination showed 2 mm wide serpig-
inous erythematous plaques with a vascular anatomic dis-
tribution on the anterior side of his left shoulder (Figure 1).
Neither cervical nor axillary adenopathies were detected.
After taking a punch-biopsy, a diagnosis of intralymphatic
histiocytosis was established.


Teaching point
Intralymphatic histiocytosis is a benign proliferation of
histiocytes within lymphatic vessels [1]. Although its etio-
pathogenesis has not yet been clearly elucidated, it has been
associated to several chronic inflammatory and degenerative
disorders, such as osteoarthritis [2]. Thus, Dermatologists
should take into account this entity whenever they are facing
serpiginous erythematous plaques with a vascular distribu-               Figure 1. 2 mm wide serpiginous erythematous plaques with a
tion on a persistent swollen joint.                                      vascular distribution on the left shoulder.



Image Letter | Dermatol Pract Concept. 2022;12(2):e2022067                                                                             1
References                                                            2. Korman JB, Burgin S, Tahan SR. Intralymphatic histiocyto-
                                                                         sis in association with severe osteoarthritis of the shoulder.
1. Takiwaki H, Adachi A, Kohno H, Ogawa Y. Intravascular or in-          J Am Acad Dermatol. 2013;69(6):e314–e315. DOI: 10.1016/j.
   tralymphatic histiocytosis associated with rheumatoid arthritis:      jaad.2013.08.020. PMID: 24238195.
   A report of 4 cases. J Am Acad Dermatol. 2004;50(4):585–590.
   DOI: 10.1016/j.jaad.2003.09.025. PMID: 15034508.




2                                                                        Research Letter | Dermatol Pract Concept. 2022;12(2):e2022067
