10.5826/dpc.1204a161
text/xml
2160-9381
2108
en
Miyuki  Kato
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
Subungual Eccrine Angiomatous Hamartoma: Description of a Novel Dermoscopic Feature
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-10-31
2021-10-17
2022-10-31
2022-11-29
e2022161
Dermatol Pract Concept
Miyuki  Kato
2022/10/31
10.5826/dpc.1204a161
e2022161
Department of Dermatology, Tokyo Metropolitan Tama Medical Center, Fuchu‐shi, Tokyo, Japan
2160-9381
en
e2022161
Subungual Eccrine Angiomatous Hamartoma: Description of a Novel Dermoscopic Feature
https://dpcj.org/index.php/dpc/article/download/2108/1801
         Subungual Eccrine Angiomatous Hamartoma:
         Description of a Novel Dermoscopic Feature
                                  Takahiro Mizuta1, Nobuo Isono2, Miyuki Kato1


1 Department of Dermatology, Tokyo Metropolitan Tama Medical Center, Fuchu‐shi, Tokyo, Japan
2 Department of Plastic and Surgery, Tokyo Metropolitan Tama Medical Center, Fuchu‐shi, Tokyo, Japan



Citation: Mizuta T, Isono N, Kato M. Subungual Eccrine Angiomatous Hamartoma: Description of a Novel Dermoscopic Feature.
Dermatol Pract Concept. 2022;12(4):e2022161. DOI: https://doi.org/10.5826/dpc.1204a161
Accepted: January 31, 2022; Published: October 2022
Copyright: ©2022 Mizuta al. This is an open-access article distributed under the terms of the Creative Commons Attribution-
NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Takahiro Mizuta, MD, Tokyo Metropolitan Tama Medical Center, 2‐8‐29 Musashidai, Fuchu‐shi, Tokyo 183‐8524,
Japan. Phone: +81-42-323-5111, Fax: +81-42-312-9156 E-mail: t.miz.cof.lif2120@gmail.com




Case presentation                                                        (Figures 1, B and C), consistent with the diagnosis of eccrine
                                                                         angiomatous hamartoma (EAH).
A 45-year-old woman presented with a 2-month history
of progressive tenderness at the tip of the left first toenail.
                                                                         Teaching Point
Clinical examination showed no gross abnormalities within
and beneath the nail plate. Nail plate dermoscopy revealed               EAH is a rare, benign combined eccrine and vascular
longitudinal yellowish-brown to yellowish-red areas with no              ­malformation located mainly on the limbs, rarely in sub-
remarkable changes in the nail plate, lunula, or proximal nail           ungual areas. To our knowledge, this is the first report on
fold (Figure 1A). Histologic examination showed increased                nail plate dermoscopic descriptions of EAH. The presence
number of eccrine glands with irregular, dilated blood vessels           of yellowish-brown to yellowish-red areas may reflect the




Image Letter | Dermatol Pract Concept. 2022;12(4):e2022161                                                                           1
Figure 1. (A) Nail plate dermoscopy revealed yellowish-brown to yellowish-red areas, which are arrayed longitudinally under the nail plate.
(B, C) Histopathology showed the hamartomatous presentation of the lobules of the eccrine glands accompanied by abnormally dilated
vessels. (H&E stain; original magnification: B, ×4; C, ×20.)



numerous dilated eccrine glands and clusters of dilated cap-           References
illaries among and around the eccrine glands, which could be
helpful in its diagnosis [1,2].                                         1. García García SC, Saeb Lima M, Villarreal Martínez A, et al.
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Acknowledgments: We thank Editage (www.editage.com)
                                                                           JDCR.2017.08.014. PMID: 29387774.
for English language editing.
                                                                        2. Kelati A, Chiaverini C, Giacchero D, Ilie M, Lacour JP, Baha-
                                                                           doran P. Dermoscopy of eccrine angiomatous hamartoma: The
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