10.5826/dpc.1203a122
text/xml
2160-9381
1800
en
Naimah Aljassem
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
greyish white septae
Retiform Hemagioendothelioma: Dermoscopic-pathological corelation
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2022-07-28
2021-05-21
2022-07-28
2022-09-15
e2022122
Dermatol Pract Concept
Naimah Aljassem
2022/07/28
10.5826/dpc.1203a122
e2022122
Department of Pathology, NMC Royal Hospital
2160-9381
greyish white septae
en
e2022122
Retiform Hemagioendothelioma: Dermoscopic-pathological corelation
https://dpcj.org/index.php/dpc/article/download/1800/1672
                   Dermatology Practical & Conceptual


                    Retiform Hemagioendothelioma:
                  Dermoscopic-pathological Correlation
                                           Saurabh Mittal1, Naimah Aljassem2


1 Department of Dermatology, NMC Royal Hospital
2 Department of Pathology, NMC Royal Hospital



Citation: Mittal S, Aljassem N. Retiform Hemagioendothelioma: Dermoscopic-pathological correlation.
Dermatol Pract Concept. 2022;12(3):e2022122. DOI: https://doi.org/10.5826/dpc.1203a122
Accepted: October 29, 2021; Published: July 2022
Copyright: ©2022 Mittal et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non
Commercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: Both authors have contributed significantly to this publication
Corresponding author: Dr. Saurabh Mittal, MD, Department of Dermatology, NMC Royal Hospital, Abu Dhabi, UAE. E-mail:
drsaurabh0811@gmail.com




Case Presentation                                                       Based on the above features, a diagnosis of retiform heman-
                                                                        gioendothelioma was made.
A-31-year-old female presented with a single, asymptomatic,
slowly growing, soft, cystic, dark-red nodule (with bluish
periphery) of size 2 cm x1 on the medial aspect of left up-
                                                                        Teaching point
per thigh, of 4-5 years duration (Figure 1A). Dermoscopy                Retiform hemangioendothelioma is a rarely infiltrative
revealed multiple deep red-colored globules of variable sizes           neoplasm, that mostly presents as an isolated growth, com-
separated by grayish white septae (Figure 1B).                          monly involving the lower limbs [1,2]. Surgical excision has
    Histology showed a tumor composed of infiltrating vas-              been used most commonly, although recurrences have been
cular channels, which was poorly circumscribed and was                  reported [2]. The unique feature observed was the grayish
composed of partially compressed, anastomosing vessels                  white septae separating the globules. Histologically, these
lined by hobnail endothelial cells. The vessels were separated          septae conformed to the attenuated fibrous walls. To our
by attenuated fibrous walls. Immunohistochemistry was pos-              knowledge, this is the first case describing the dermoscopic
itive for CD34 highlighting the florid vascular proliferation.          features for this entity.




Image Letter | Dermatol Pract Concept. 2022;12(3):e2022122                                                                          1
Figure 1. (A) Clinical picture showing dark-red nodule. (B) Dermoscopy (Dermlite 10x) revealing multiple deep red-colored globules of
variable sizes separated by grayish white septae.




References                                                           2. Nobeyama Y, Ishiuji Y, Nakagawa H. Retiform hemangioendo-
                                                                        thelioma treated with conservative therapy: report of a case and
 1. Requena L, Kutzner H. Hemangioendothelioma. Semin Diagn             review of the literature. Int J Dermatol. 2016;55(2):238-243.
    Pathol. 2013;30(1):29-44. DOI: 10.1053/j.semdp.2012.01.003.         DOI: 10.1111/ijd.12908. PMID: 26267121.
    PMID: 23327728.




2                                                                          Image Letter | Dermatol Pract Concept. 2022;12(3):e2022122
