10.5826/dpc.1303a156
text/xml
2160-9381
2972
en
Mohamed Denguezli
https://creativecommons.org/licenses/by-nc/4.0
Dermatology Practical & Conceptual
A Congenital Plaque-Like Myofibroblastic Tumor
Text.Serial.Journal
https://dpcj.org/index.php/dpc
Image Letter
2023-07-31
2022-11-13
2023-07-31
2023-08-24
e2023156
Dermatol Pract Concept
Mohamed Denguezli
2023/07/31
10.5826/dpc.1303a156
e2023156
Dermatology Department, Faculty of Medicine of Sousse, Farhat Hached University Hospital, Sousse, Tunisia
2160-9381
en
e2023156
Moulonguet, I. et al. Plaque-Like Myofibroblastic Tumor: Report of 4 Cases. Am J Dermatopathol 39, 767–772 (2017).
A Congenital Plaque-Like Myofibroblastic Tumor
https://dpcj.org/index.php/dpc/article/download/2972/2229
    A Congenital Plaque-Like Myofibroblastic Tumor
       Haifa Mkhinini1, Nadia Fetoui Ghariani1, Badreddine Sriha2, Mohamed Denguezli1


1 Dermatology Department, Faculty of Medicine of Sousse, Farhat Hached University Hospital, Sousse, Tunisia
2 Anatomopathology Department, Faculty of Medicine of Sousse, Farhat Hached University Hospital, Sousse, Tunisia



Citation: Mkhinini H, Fetoui Ghariani N, Sriha B, Denguezli M. A Congenital Plaque-Like Myofibroblastic Tumor. Dermatol Pract
Concept. 2023;13(3):e2023156. DOI: https://doi.org/10.5826/dpc.1303a156
Accepted: January 4, 2023; Published: July 2023
Copyright: ©2023 Mkhinini et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-
NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use,
distribution, and reproduction in any medium, provided the original authors and source are credited.
Funding: None.
Competing interests: None.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Haifa Mkhinini, Resident, Faculty of Medicine of Sousse Dermatology Department, Farhat Hached University
Hospital, Sousse, Tunisia. E-mail: Haifa.mkhinini90@gmail.com




Case Presentation                                                        within the first 4 years of life [1]. This tumor typically presents
                                                                         as a slowly growing firm, red-brown colored, papulonodular
A 6-month-old boy presented with a history of congenital                 plaque, mostly localized on the lower back [1]. Clinical dif-
plaque on the right peri axillary region. Physical examina-              ferential diagnosis includes giant dermatofibroma, multiple
tion revealed an irregular violaceous, infiltrated plaque with           clustered dermatofibroma and dermatofibrosarcoma protu-
central fine scales, measuring 30mm x15 mm (Figure 1A).                  berans. Histopathological examination shows the same fea-
Dermoscopy showed structureless whitish and violaceous                   tures as dermatofibroma, but immunohistochemistry favors
areas, some dotted vessels and a thin peripheral pigmented               a myofibroblastic lineage [1]. Recurrence after surgical exci-
network (Figure 1B). Histopathological examination of a                  sion is reported [2].
skin biopsy showed a proliferation of spindle cells extend-
ing throughout the reticular dermis, arranged in a storiform
pattern and separated from the epidermis by a grenz zone.                References
The superjacent epidermis was hyperplastic with hyperpig-                 1. Sekar T, Mushtaq J, AlBadry W, et al. Plaque-like Myofibro-
mentation of the basal layer (Figure 1, C and D). Immuno-                    blastic Tumor: 2 Cases of This Unusual Dermal Tumor Which
histochemistry demonstrated diffuse positivity for smooth                    ­Occurs in Infancy and Early Childhood. Pediatr Dev Pathol.
muscle actin (Figure 1E) while immunostaining for CD34                        2018;21(5):444-448. DOI: 10.1177/1093526617746807. PMID:
                                                                              29224420.
was negative. The diagnosis of plaque-like myofibroblastic
                                                                          2. Moulonguet I, Biaggi A, Eschard C, et al. Plaque-Like Myofi-
tumor (PLMT) was made.
                                                                              broblastic Tumor: Report of 4 Cases. Am J Dermatopathol.
                                                                              2017;39(10):767-772. DOI: 10.1097/DAD.0000000000000869.

Teaching Point                                                                PMID: 28930106.


PLMT is a rare, benign pediatric tumor, firstly described in
2007. It occurs commonly in infants and young ­children




Image Letter | Dermatol Pract Concept. 2023;13(3):e2023156                                                                                1
Figure 1. (A) Violaceous nodular plaque of the right peri axillary region. (B) Dermoscopy showed whitish and violaceous areas, peripheral
pigmented network and dotted vessels. (C) Acanthosis, proliferation of spindle cells within the reticular dermis (H&E, ×200) arranged in a
storiform pattern (D) (H&E, ×200). (E) Strong positivity for smooth muscle actin.




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