10.6092/issn.2038-3460/17084
In addition to being one of the most iconic of the new reproductive technologies introduced in the late twentieth century, in vitro fertilization is also a technology of representation – a looking glass into conception, a window onto early human development, and as such a new form of public spectacle. Still a rapidly expanding global biomedical service sector, IVF technology is also the source of new images of human origins, and thus offers a new visual grammar of coming into being. This lecture explores these connections, and argues that the micromanipulation imagery associated with IVF, and now a routine feature of news coverage and popular debate of NRTs, also introduces a new connection between cells and tools, thus returning us to one of the oldest sociological questions – the question concerning technology. Moving between IVF as a technology of reproduction, and a visual technology, enables us to revisit a series of broad sociological questions concerning technology, reproduction, genealogy and the future of biological control from the unique perspective offered by the conversion of the human embryo into both a tool and a lens.
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Sarah Franklin
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Tecnoscienza – Italian Journal of Science & Technology Studies
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Embryo Watching: How IVF Has Remade Biology
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Lectures
2013-07-12
2023-05-30
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Sarah Franklin
2013/07/12
10.6092/issn.2038-3460/17084
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visual culture
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Embryo Watching: How IVF Has Remade Biology
https://tecnoscienza.unibo.it/article/download/17084/16004
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                                                                           Lecture
Embryo Watching
How IVF Has Remade Biology
!
Sarah Franklin
University of Cambridge
!
    Abstract In addition to being one of the most iconic of the new reproduc-
    tive technologies introduced in the late twentieth century, in vitro fertiliza-
    tion is also a technology of representation – a looking glass into conception,
    a window onto early human development, and as such a new form of public
    spectacle. Still a rapidly expanding global biomedical service sector, IVF tech-
    nology is also the source of new images of human origins, and thus offers a
    new visual grammar of coming into being. This lecture explores these con-
    nections, and argues that the micromanipulation imagery associated with IVF,
    and now a routine feature of news coverage and popular debate of NRTs, al-
    so introduces a new connection between cells and tools, thus returning us to
    one of the oldest sociological questions – the question concerning technolo-
    gy. Moving between IVF as a technology of reproduction, and a visual tech-
    nology, enables us to revisit a series of broad sociological questions concern-
    ing technology, reproduction, genealogy and the future of biological control
    from the unique perspective offered by the conversion of the human embryo
    into both a tool and a lens.

    Keywords IVF; micromanipulation; human embryo; biological control; visual
    culture.

    Corresponding author Sarah Franklin, Department of Sociology, Free
    School Lane, Cambridge CB2 3RQ, United Kingdom - Email:
    sbf25@cam.ac.uk



1. Introduction
    Although its first human offspring were not born until the1970s, in
vitro fertilization is now at least a century old, and is itself the product of
many generations of accumulated scientific expertise. Early efforts to
achieve fertilization in glass included the novel experiments on partheno-
genesis undertaken by Jacques Loeb at the turn of the century, but his
use of the sea urchin body as itself a kind of translucent container hint at
an even longer history of embryo watching (Loeb 1913; Pauly 1987). A

!
TECNOSCIENZA
Italian Journal of Science & Technology Studies
4(1) pp. 23-43 – ISSN 2038-3460
www.tecnoscienza.net                              2013
24                                                            Tecnoscienza - 4 (1)

key to understanding the eventual success of IVF in higher vertebrates in
the post-war period is the shift that occurred in the study of embryology,
from the late nineteenth century onwards, whereby the study of the earli-
est stages of biological development changed from being a largely de-
scriptive project into one that involved forcing new kinds of life out of
manipulated cells and organisms (Franklin 2013). This shift, described by
both Philip Pauly (1987) and Hannah Landecker (2007) as a process of
“taking life in hand”, cannot be separated from the evolution of tech-
nique in the context of embryology, for example the development of new
culture media, micromanipulation methods, visualisation technologies,
and new model organisms. It is also a shift that marks a turn from watch-
ing into more explicit forms of making, and the ultimate ‘designer baby’
to emerge out of this line of thought would be a fully synthetic embryo –
a prospect toward which the functional iPS cell (named for the iPhone)
gestures. The merging between what Ian Hacking (1983) describes as
“representing and intervening” to produce what Evelyn Fox Keller has
called “the biological gaze” (1996) are both central and indispensible to
what we might call, after Sharon Traweek (1988), the culture of embryo
culture. Like all scientific cultures, this project is at once local and inter-
national, personal as well as professional, and today it is increasingly ori-
entated toward the development of new translational technologies such as
stem cell research and regenerative medicine.
     Notably, atypically, and for complex reasons that are beyond the
scope of this lecture, the professional scientific culture of embryo re-
search has increasingly become more prominent both within and outside
of the scientific laboratory in the midst of biology’s ‘big bang’. As the
Norwegian anthropologist Merete points out in her cultural analysis of
contemporary cellular imagery, “cellular images have gained aesthetic as
well as dramatic appeal, as they have moved out of the laboratory and be-
come available for the public” (2012, 475). As she also notes, “images of
(...) cells related to techniques of assisted reproduction” are central to this
process. Indeed, there is no doubt that IVF is the primary technique
through which the most famous of the newly mediagenic human cells, the
human embryo, has become increasingly public visible, legible and even
iconic. The unexpectedly dramatic and rapid expansion of IVF technolo-
gy as a form of both reproductive biomedicine and basic scientific re-
search is both exceptional and arguably under theorised in general, as
well as in relation to the question concerning technology, or more specifi-
cally, the technics of visualisation. In addition to becoming both a plat-
form technology and a way of life, IVF has been implanted into popular
consciousness over the past three decades as a set of visual images and
narratives depicting ‘live’ embryological procedures such as fertilization,
micro-injection, embryo biopsy, genetic diagnosis, stem cell propagation,
mitochondrial replacement therapy, and nuclear transfer, to name only
the most recent and well established genres within what we might call the
bioptical imaginary. The rapid routinization of IVF has been central to
Franklin                                                                           25
the introduction of a new visual language of reproduction that is particu-
larly striking in its vivid depiction of the merger between reproductive
cells and hand held tools. Like the language of genes and DNA, the imag-
es and idioms through which IVF has come to be understood as a “help-
ing hand” (Strathern 1992a; 1992b; Franklin 1997) have travelled far and
wide, introducing a new version of ‘the facts of life’ as a union of cells and
tools. Part of the way IVF has become more comfortable and familiar is
through a kind of mass public education in reproductive biology so that
the human gamete in a Petri dish now recognizably codes for a celebrated
arena of medical scientific innovation and capacity as well as for a “mira-
cle baby” and a “hope technology” (Franklin 1997). Indeed, these in-
creasingly familiar visual images have arguably become the dominant vis-
ual signifier of the expansion of the IVF platform over the past half cen-
tury, if not for ‘the age of biology’ in general. Like ultrasound imagery,
with its ability to convey the live action of pregnancy as a screen image,
IVF offers privileged visual access to the previously unseen events of early
human life – and indeed is popularly associated with precisely this capacity.
    This lecture explores the emergence of a new visual culture of manip-
ulated reproductive cells, and their circulation as a highly public spectacle
that refigures sex as something that is made. Visual imagery is essential to
this process. In order to be taken in hand, the IVF embryo must first be
made available to the eye, and once it has been transformed into an im-
age, it can be circulated across the increasingly broad range of media that
include newspapers, magazines, the internet and the scholarly literature.
Unlike in the nineteenth or early twentieth century, the technological
means of broadcasting high quality colour images, and their easy repro-
ducibility, enables them to proliferate within the vast digital networks of
contemporary culture, and thus to establish a new ground state for what I
am calling the ‘global biological’. The interface between IVF technology
and its worldwide audience, who are increasingly literate in its language
of visual form, reveals how ‘live IVF’ circulates as a different kind of
shared technological substance, and virtual life, as an iconic spectacle of
artificial biology. IVF is thus a ‘culture media’ in more than one sense of
the term. IVF is an example of a local biology that has become a global
one, and this lecture explores this interface1.


!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
1
  I have used the term “global biological” elsewhere to describe stem cells, using
‘global’ in two interlinked senses. Stem cell science is both part of a global biolog-
ical enterprise, and is dedicated, as was the human genome project, to the depic-
tion of global aspects of the biological, as in their totality. The vast banks, regis-
tries and depositories of substances ranging from human blood and genes to stem
cells and mouse models comprise global biological projects both in their reliance
upon a high degree of global cooperation among scientific teams and their goal of
better characterizing the global properties of phenomena such as cellular potency.
See further in Franklin (2004, 60-62).
26                                                            Tecnoscienza - 4 (1)

    IVF is of course (and among other things) a very famous technology –
perhaps even a technology that to a certain extent epitomizes what a
technology is imagined to be and to do, and images of IVF are thus also a
sign of the technological (especially where it meets the biological). The
difference between conception via IVF and unassisted, natural, or ‘spon-
taneous’ conception is precisely what is celebrated by the adjectives ‘pre-
cious’ or ‘miracle’ commonly used to mark IVF babies as ‘special’. As
Stewart Brand (2010) observes in his manifesto for synthetic biology,
Whole Earth Discipline, what is also iconic about IVF babies is that de-
spite their artificial or ‘test-tube’ origins, the viable offspring of IVF are
indistinguishable from ‘regular’ children. This is another of the unifica-
tions IVF can be seen to perform, by linking the normal and the techno-
logical biologically. In this lecture, I explore the public face of IVF as a
set of visual images to explore the question of how this technology of re-
making sex has itself become conventional – a new reproductive norm
that is based on taking biological reproduction ‘in hand’. The turn here,
to IVF as a technology of representation as well as reproduction, adds
another crucial layer to the question of why it is so popular despite the
fact that it, still, usually fails in a majority of cycles.


2. The Baby in the Bottle
    As Susan Squier points out in her analysis of the twentieth century his-
tory of the image of the baby in the bottle (1994), IVF technology has a
powerful visual and literary genealogy which can be read, among other
things, as a series of reflections on the reproductive politics of gender and
sex filtered through the lens of artificial conception. Looking back to the
nineteenth century, Squier points, for example, to feminist readings of
Mary Shelley’s Frankenstein and its critique of “the new male birth of fra-
ternal contractual democracy” with its “male monopoly on political crea-
tion” as well as her “powerful critique of the newly revised institution of
mothering.” Together these themes have been argued to converge in
Shelley’s creation of “a nightmare image of scientific procreation that an-
ticipates IVF” (Squier 1994, 15). In the early twentieth century, she ar-
gues, these themes continued to proliferate in a host of tales, fables, nov-
els, and children’s stories featuring technologies of embryology and re-
production, and the moral, scientific and political questions they raised.
From Charles Kingsley Amis’s The Water Babies, to Julian Huxley’s Tis-
sue Culture Kings, John Burdon Sanderson Haldane’s essay on Daedalus,
or the Science of the Future, the prolific writings of his sister Naomi
Mitchison, and their close friends and colleagues Aldous Huxley, Vera
Brittain, John Desmond Bernal, and Herbert George Wells, in whose
writings the figures of ectogenesis, cloning, and artificial reproduction
conspicuously serve as the lens through which definitions of the future,
and future technologies, are both imaged and imagined. As Squier notes,
Franklin                                                                           27
these stories produced by a highly scientifically literate group of friends
and kin (many of whom were closely biologically related as well as related
through the study of biology) typically wove together elements from the
history of embryology with science fiction, even sometimes very accurate-
ly predicting the future, as in Haldane’s account of the young Cambridge
undergraduate who successfully develops IVF (1924). As Squier (1994,
71) notes:

                Haldane’s story of the development of in vitro gestation par-
           allels the actual story of the development of in vitro fertilization,
           as told in Dr Robert Edwards’s autobiographical account. Both
           narratives move from successful animal embryology to advances
           in human embryology.

     And yet, as she points out, Haldane’s story – first delivered as a lec-
ture in Cambridge to the Heretics Society – is also couched in the lan-
guage of myth, narrating the victory of Daedalus over Prometheus as con-
firmation that biology has become the “pivotal” science for the twentieth
century. Thus, “Daedalus looks cheerfully ahead to a future in which the
invention of ectogenesis enables the control of human reproduction, the
improvement of the human species, and finally the emancipation of man-
kind” (Squier 1994, 73).
     In the same way that Squier argues the complex interwoven plots of
Haldane’s vision of ectogenesis united British biofuturists, humanists, and
socialists with their detractors throughout the 1920s and 1930s in a de-
bate over reproductive technology, so too can this period be understood
in Foucauldian terms as an extension of the “entry of the phenomena pe-
culiar to the life of the human species into the order of knowledge and
power [and] the sphere of political techniques” (Foucault 1990, 141-2).
Except that, to be precise, it is not merely sex, or even sexuality, in these
debates that serves as the “pivot of the two axes along which developed
the entire political technology of life”, as Foucault (1990, 145) suggests,
but a more literal technologization of reproduction in the form of taking
it ‘in hand’. It is artificial reproduction and ectogenesis that are pivotal in
this debate about the future of the human – just as they have continued to
be since.
     Squier’s account can help us to move more explicitly into the realm of
IVF as a contemporary, twenty-first century representational field, or
what I will describe as the visual logic of IVF, and in particular its role as
a symbolic image coupling biology and artifice. What is notable in
Squier’s account is the sheer amount of imaginative reconstruction of sex,
gender, kinship and reproduction that is occurring through the lens of
‘the baby in the bottle’ in this period. New possibilities of regeneration as
well as recombination, in the form of chimeras, hybrids and mosaics, as
well as cloning, transhumanism, and ectogenesis, are in free play amidst
the questioning of traditional gender and kinship (and economic) orders
28                                                                 Tecnoscienza - 4 (1)

in the early-twentieth century. As Squier herself suggests, the history of
the baby in the bottle supplies a prehistory for IVF in which this tech-
nique plays a far more radical role than its use as a ‘renormalizing’ tech-
nology in the present might suggest.


3. Screening IVF
    As it is crucial to the history of in vitro fertilization that it provided a
technological platform through which reproductive substance could be
both seen and handled, so too is it equally crucial for IVF as a representa-
tional technology that it has, in this sense, a ‘natural’ visual interface with
the mainstream media – among other things, it is a screen-based technol-
ogy. As we have seen with the dramatic success of the iPhone, the intro-
duction of the hand-held screen is in itself an iconic moment for the his-
tory of human technologies, enhancing the hand-tool relation by intensi-
fying its depth as well as scale. IVF too is a powerful hand-held screen
window onto early life that achieves a similar, if less portable, marriage
between visualization and manipulation – and one that is greatly ampli-
fied by the capacities of micromanipulation harnessed to digital repro-
duction.




     Fig. 1 – IVF. This author photo of an iPhone photo of a hand-held camera
     photo of an iPhone photo of a textbook reproduction of a digital photo of an
     IVF embryo illustrates the easy reproducibility of the digital embryo online,
     on screen, and thus a new version of Benjamin’s “work of A.R.T. in the age of
     mechanical reproduction”.
Franklin                                                                    29

     Crucial to the visual logic of IVF on screen is the fact that what we are
looking at when we observe a fertilized egg, or embryo, in a Petri dish –
or the manipulation of an egg or embryo in one of these handy chambers
– is no ordinary sight. For many people, scientists, clinicians, and patients
alike, witnessing a live human embryo is ‘special’. Images of early human
life – be they of gametes, embryos, or foetuses – are distinctively media-
genic in that they merge highly specialized scientific imaging apparatus
with intimate human biological substance, condensed into a spectacle of
shared origins. This makes of such images an especially suggestive primal
scene of the new reproductive mechanics brought about by assisted con-
ception, and it is not surprising much has been written about embryos as
visual objects (Franklin 1999; Hopwood 1999, 2000, 2009; Dubow 2009;
Morgan 2009)2. As many artists as well as news editors and lobbyists have
recognized, contemporary embryological imagery is a potent contact-zone
uniting scientific research, high tech laboratory apparatus, biological sub-
stance, and powerful visualizing techniques with the promissory future of
‘the age of biology’. These images at once sign the beginnings of human
life, and shared human futures, while also depicting a shared, and unique-
ly human, technological legacy manifest as highly specialised craft (thus a
second sign of being-ness as human technological agency). The images
both reproduce and model a fusion of accumulated scientific knowledge,
human reproductive substance, and technological artifice, multiply over-
determining the viewer position of witnessing ourselves, our technology,
our future, and our obligations to one another. In this sense, and as the
artist Suzanne Anker has poignantly suggested, the in vitro lens is also a
mirror (Anker and Franklin 2010).
     Importantly, and unlike other reproductive screening technologies,
such as ultrasound, IVF imagery establishes a viewer position that is only
made possible by the direct manipulation, or handling, of what is shown.
In the very fact of these images’ existence is the structuring presence of
the technologies that make them possible, the hands that hold the tools,
the tools that manipulate the cells, the dishes that contain the materials,
the knowledge of how to do all of these things, and the screens that dis-
play these scenes. All of this equipment depends upon the histories of
technique that have been passed down as part of the still artisanal culture
of laboratory labour, and the logics that make such scientific interven-
tions both possible and desirable. The sense of being hands on is irrevo-
cably part of what IVF imagery reveals, from a spectator position that re-
produces the point of view of the manipulator. Thus the viewer of these
images is always-already visually implicated in the substantive and con-
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
2
 For a superb online resource on the visual culture of embryology, see Hopwood
and Buklijas (2008) Making Visible Embryos, http://www.hps.cam.ac.uk/-
visibleembryos. Bioartists have also made use of human embryos in projects such
as Helen Chadwick’s Unnatural Selections (1996).
30                                                                 Tecnoscienza - 4 (1)

ceptual connections they establish: the double-grip of the hand-held tool
securing the manipulated cell in place, and the screen that holds the im-
age in focus within its frame, ‘grip’ the object the viewer is shown3.
Hence, in addition to the practical or scientific questions posed by these
primal scenes (how does life begin, what are its mechanisms, how do they
work), and their “special” content (early human life, shared origins, po-
tential offspring, cures for disease, etc.), there is an additional visual sig-
nificance to the form of spectatorship Evelyn Keller (1996) describes as
“the biological gaze”, because the very ability to witness these objects ref-
erences a prior series of interventions that has ‘allowed us in’ as viewers;
looking, as we inevitably must, through the keyhole science has provided
into a formerly hidden domain. It is impossible, in other words, to view
an image of an in vitro embryo without inhabiting the position of its han-
dler.
    The popular version of the reproductive gaze inaugurated by the foe-
tal photography of Lennart Nilsson in the 1960s, and now manifest as the
contemporary imagery of IVF, stem cells, cloning, is derivative of IVF’s
history as a research tool, both in its logic and its logistics. In the same
way that IVF was dependent upon earlier forms of embryo watching, so
have later forms of this art come to depend on IVF. However an im-
portant shift has occurred since the 1960s, when both the images of the
earth taken from outer space, and the images of inner space published in
Life magazine, provided unprecedented visual access to aspects of the
human condition that were previously unwitness-able. As noted in the
extensive literature on the Nilsson images (Petchesky 1987; Franklin
1991, 1999; Hartouni 1992; Stabile 1992; Duden 1993; Kaplan 1994;
Newman 1996; Michaels 1999; Franklin et al. 2000; Dubow 2009) and
the ‘blue planet’ photographs (Kelley 1988; Duden 1993; Macnaghten
and Urry 1998; Franklin et al. 2000; Cosgrove 2001; Poole 2008), part of
the sense of awe generated by these now iconic twentieth century images
derives from the absence of any visible technology within the photo-
graphic frame. The power of these photographs thus derives in part from
the combination of their inferred technological potency and its absence
from view. The only ‘handle’ these photographs offer is their frame.

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
3
  Focusing the camera lens is essential to capturing a sharp image, and in the pro-
duction of high quality cinematic images in the film industry the focus puller is
assisted by the dolly grip, who moves the camera dolly to a preset mark while the
focus puller adjusts the lens in tandem. A dolly grip will also assist a camera oper-
ator shooting through a hand-held device in order to guide him or her along a
predetermined path. To make images of embryos, the camera operator in the la-
boratory (who would normally be working alone) captures a sharp image by mov-
ing the plane of focus up and down. The ‘grip’ that is provided by the focal plane
is so narrow that is essential the equipment is bolted to the floor, often onto a
heavy stone or metal surface, without the stability of which micromanipulation
imagery is much more difficult to produce.
Franklin                                                                   31
    In contrast to such ‘portrait’ images, the relationship of technology to
its objects in the visual culture of IVF is all about the explicit intimacy
between tools and cells. Far from absent, the technological ‘handles’
through which cells are manipulated are not only often prominent in im-
agery of reproductive cells in glass: the tools are also often moving, as if
alive, as in the signature image of micro-injection. Like ultrasound image-
ry, which gains in vividness what it loses through lack of focus through its
ability to convey the live movement of the foetus in utero in real time, the
newly iconic imagery of micromanipulation, like the popular short clips
of beating stem cell colonies (the poster image for regenerative medicine),
relies on a different visual vocabulary to the poignant still portraiture of
the Nilsson foetus. The enlivening of tools, especially in contrast to the
immobilisation of the cells with which they share the amber limelight,
comprises a significant departure from earlier forms of reproductive im-
agery, as will be discussed in further detail below.
    If the Nilsson imagery introduced a form of reproductive witnessing,
or spectacle, which heralded the emergence of the public human embryo
and foetus, the early twenty-first century equivalent of embryo watching
can be found in images of micromanipulation. The ‘taking in hand’ of re-
productive substance is now both familiar and quotidian in the form of
publicly broadcast ‘live’ images, such as those used to illustrate news sto-
ries about cloning, stem cell research, and new reproductive technologies
such as IVF. The now increasingly common flat-screen image of mi-
cromanipulation, for example, routinely displays a cell secured in place
by a holding pipette on one side being penetrated by a micro-injection
needle, a biopsy pipette, or some other micro-tool on the other.




  Fig. 2 – Micromanipulation. A Google image search of IVF quickly reveals
  dozens of micromanipulation images, such as this one, from a BBC website,
  where it is subtitled “IVF – in vitro fertilisation” (http://www.bbc.co.uk
  /schools/gcsebitesize/science/aqa/nervesandhormones/controlinthehumanbo
  dyrev5.shtml, accessed 20 November 2012).
32                                                                Tecnoscienza - 4 (1)


    Such imagery has become a powerful and ubiquitous contemporary
visual shorthand for union of technology and biology in the name of re-
making life across a wide range of techniques from somatic cell nuclear
transfer and transgenic animal production to preimplantation genetic di-
agnosis and aneuploidy screening.




     Fig. 3 – Embryo biopsy. Image of embryo biopsy from 11 March 2011 cover-
     age of mitochondrial disease testing from the Daily Telegraph subtitled: “A
     controversial IVF technique involving the DNA from three people is to be as-
     sessed by Government regulators”.


    The familiar micromanipulation scene typically appears as a horizon,
the pipette-cell-pipette fusion bisecting the frame in an assemblage that
now codes for biotechnological investigation writ large. As Merete Lie
(2012, 478) argues: “With a combination of new medical imaging tech-
nologies miniscule parts of the body, like cells and even the interior life of
a cell, are materializing. Imaging technologies can transform human cells
into astonishing and aesthetically appealing images.” It is these explicit
images of cellular manipulation, greatly magnified and often shown in live
motion, which have inaugurated the mass witnessing of new flows of re-
productive and genetic substance in a spectacle of re-engineering at the
ground zero of built biology. Already iconic, micromanipulation imagery
is used in advertising, corporate logos, and on fashionable club wear and
CD covers, as well as being featured on the evening news, in mainstream
films, and documentary accounts of new reproductive technologies such
as cloning.
Franklin                                                                         33
    Although, as noted above, it differs from earlier reproductive portraits
in important and distinctive ways, the image of micro-manipulation
shares a visual kinship with earlier iconic images uniting the logics of life
and technology with the question of human obligations to the future, eth-
ical horizons, and questions of “life itself” (Franklin et al. 2000). Like the
foetus and the blue planet images, the cell at the center of the microma-
nipulation image glows with a radiant light – often blue or amber -- com-
bining the ethereal beauty of life’s innate mystery with the power of the
bioscientific gaze. Unlike such earlier images, however, the distinctly
planetary cell becomes a window onto the ability to re-engineer biological
interiority. With its faintly visible cumulus, or corona, the cell appears to
emit vitality, or energy, as a kind of bio-luminescence, but it is not ‘float-
ing in space’. The cell is at once bounded and permeable, ‘captive’ and
already joined with the tools that hold it in place. Translucent, it is also
somewhat opaque, with an obscure and grainy interior, lacking depth of
field, while at the same time the tools convey a sense of reach ‘beyond’
the visible frame, or edge, of the image. Structuring the image is the shal-
low plane of focus, which, like the holding pipette, positions the cell se-
curely in flat visual grip. Like a living Petri dish, the micromanipulation
set-up handily presents a visually engaging biopic of tools that are the
source of new life and poised to grasp, probe and penetrate the cell’s in-
terior. In particular, the image of micro-injection, in which a needle is
shown penetrating an egg cell, recapitulates the familiar ‘moment’ of con-
ception, restaging the conventional denouement of the sexual union of
egg and sperm, and thus life’s beginnings (Martin 1991). Instead of the
agency of fertilization being carried by the substance ‘itself’, however, mi-
cromanipulation images of fertilization depict the helping hands of sci-
ence as the active agents, which assume the activity formerly assumed to
be merely biological, self-acting, or naturally automatic. Here, then, are
the new mechanics of making sex – replacing and extending biological
action in the form of hand-held tools.
    In contrast to the still portraits of the foetus or the blue planet, the
scene of micro-injection is cinematic, and the movement of the microma-
nipulation tools is the main ‘story’ these images convey, and emphasize4.
Notably, these are more evidently ‘working’ screen scenes than the earlier
images of inner and outer space, often linked in newsreel footage with
scenes of white-coated scientists at work in their labs5. The cell in these

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
4
  As both Lisa Cartwright (1995) and Hannah Landecker (2006) have document-
ed, the history of the cinema has its origins in the effort to explore the mechanics
of cell biology.
5
  The contrast is particularly evident in relation to Nilsson’s photos, the work of
preparation for which is noticeably absent, as it is only the finished object in the
form of a photograph he sought to produce, much as an earlier generation of
specimen collectors artfully arranged their display objects in glass containers (an-
other important lineage of in vitro imagery, see Anker and Franklin 2010).
34                                                             Tecnoscienza - 4 (1)

images is tightly coupled to its tools, engaged in a process of itself being
re-tooled, whereby its internal mechanics will be recomposed, repro-
grammed, and remade. This is the bespoke wet life of the biotechnology
lab in the making – no longer the pristine, untouched, ‘natural’ life of the
planet or the foetus, part of whose grandeur lay in the autonomy of their
inherent and ultimately mysterious life-giving properties, which exceed
and predate even our most powerful means of technological creation.




Fig. 4 – Stem cell research - The Telegraph 19 October 2010 ‘Stem cell research:
a new age dawns in healthcare’6


    The new animated digital embryological imagery also differs from ear-
lier photographic reproductive portraiture in not being self-contained:
this imagery does not remain within the frame. Whereas Nilsson’s foetal
portraits employed the margins of the photograph to foreground the cap-
tured object alone, thus delivering visual set pieces which speak for them-
selves partly through the autonomy of the foetal body, the scene of mi-
cromanipulation always extends off-screen, breaking through the frame
of the image along the trajectory of the handles of the micro-tools. These
tools, and the camera, thus become the connections linking the cell to the
modus operandi of the micromanipulation station, and the guiding hands
and eyes of its live operator. The manipulation tools are scaled precisely
to cellular dimensions to create a workable fit between the microscopic
object and the prosthetic hands of the operator who will delicately recon-
struct it, and so the tools are also magnified. So too are their movements,
creating the slow, jerky, groping drama of connection between tools and
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
6
 http://www.telegraph.co.uk/health/8072484/Stem-cell-research-a-new-age daw–
ns-in-healthcare.html, accessed 20 November 2012.!
Franklin                                                                    35
cells depicted in the now-familiar genre of animated films that unite cells
and tools against the blurry background and the flat light that is only
barely gripped or visible within an almost impossibly thin plane of focus.
These effects of scale, dimension, perspective, framing, and context re-
produce the scientific gaze, its instruments, and its object – as well as its
labour ‘exactly’ while at the same time rendering fragile and tentative the
very connections they depict.
    The confident-yet-ambivalent message these images communicate is
particularly pronounced in the blurring of the tool and object they so viv-
idly reveal. In the magnified image of micromanipulation, the aqueous
environment of the cell is evident in the viscosity of its contents, which
can be seen and sensed in the flows of substances within the hollow glass
tools themselves. Like the cell, the instruments are transparent, enabling
us to both see and see through this multi-layered scene of fertile coupling
between tools and cells. In a kind of respiratory movement, the injection
needle appears to inhale cellular contents for removal, and to exhale new
material into the cell’s interior. In this sense, micromanipulation imagery
mechanically imitates a metabolic symbiosis of parts. And indeed this is
precisely what is occurring. Micromanipulation takes place on cells that
are typically submerged in clear sterile oil, using tiny glass tools as thin as
strands of hair. The micro-tools are secured with small clamps that attach
them to hydraulically-driven ‘joy sticks’ that allow the manipulator to
conduct various procedures, using touch as much as sight to guide his or
her movements. The eyepieces are connected to a video lead that allows
the manipulator to view the ‘bed’ of the machine on a monitor, and to
record, transmit, or display and further enlarge these processes on screen.
To view the contents of a cell takes a practiced eye, as there is little con-
trast, for example, between tiny semi-transparent organelles, such as the
multiple pro-nuclei, and the rest of the cell contents, consisting largely of
cytoplasm (Franklin 2003). It is for this reason that a colour filter is often
used, to aid the manipulator in identifying the various parts of the cell by
increasing resolution through contrast.
    For both clinical and scientific procedures, there are five basic micro
tools, which are used for manipulating eggs, embryos and sperm:

    1) The holding pipette to fix and position the oocyte or embryo dur-
       ing a procedure;
    2) The sharp microneedle to create an opening in the zona pellucida
       or shell of the egg;
    3) The blunt-edged biopsy micropipette 15-16 um in diameter for
       polar body removal;
    4) The angled micropipette 25-30 um in diameter for blastomere bi-
       opsy;
    5) The finely pulled micropipette of 7-8 um inner diameter bevelled
       to a 30 degree angle with the tip pulled to form an ICSI insertion
       tool.
36                                                               Tecnoscienza - 4 (1)


    Additional varieties of micropipette for human embryonic cell line
procedures are commonly forged by hand by softening a glass capillary
tube over a burner and pulling it to form the desired width and tip to
serve a particular purpose. Mechanical pipette pullers can also be used,
and increasingly commercially prepared micropipettes are used in order
to conform to industry standards. Two additional instruments, a micro-
forge and a beveller, are used to fashion specialized features of these glass
tools. In addition to controlling for the diameter of the end of the mi-
cropipette, and sharpening, bevelling, or flame-polishing (blunting) of the
tip, micro-tools are bent at the attachment end to an angle commensurate
with the bed of the micromanipulator, so that they can be positioned par-
allel with each other, and with the machine. As well as precision and pre-
preparation, sterility is essential to the practice of micromanipulation
techniques such as microinjection or embryo biopsy. For example, newly
made tools may be exposed to ultra-violet radiation before use for up to
20 minutes to sterilize them, and cells are immersed in sterile equilibrated
mineral oil during manipulation procedures. Purity has become more im-
portant to micromanipulation technology as the IVF platform has ex-
panded various kinds of genetic testing, screening, and diagnosis, and the
derivation of human ESC lines. The presence of male gametes adhering
around the cumulus cells of the ova is potentially the cause of misdiagno-
sis when an embryo needs to be screened for molecular abnormalities, or
contamination of a cell line7.
    The most common micromanipulation procedure in the context of
contemporary reproductive biomedicine is ICSI, intracytoplasmic sperm
injection, now used both to enhance the purity of IVF embryos (by elimi-
nating excess, potentially contaminating sperm), and to increase the ferti-
lization rate of the limited egg supply by ensuring that the sperm pene-
trates the tough outer coat of the egg. Scenes of ICSI dominate the mi-
cromanipulation imagery made available to a wider audience, both be-
cause they are readily available, and perhaps because they replay a “famil-
iar scene” of conception, involving penetration of the egg with the sperm-
containing injection needle. This refiguration of the ‘moment of fertiliza-
tion’, however, is, like IVF in general, both like and unlike its unassisted
counterpart. As the following instructions for ICSI emphasize, the roles
of the egg and sperm are significantly altered in this new, technologically
assisted, version of the ‘drama’ of life’s beginnings:



!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
7
 The reliance on microinjection in the context of assisted conception has become
more routine due to the increasingly standardised use of ICSI, intra-cytoplasmic
sperm injection, in IVF in order to avoid contamination of the egg’s environment
during fertilization. ICSI is also used in order to avoid sperm cell contamination
when performing polar body removal or blastomere biopsy.
Franklin                                                                             37
                Under control of the stereomicroscope the washed sperm are
           added to the drop containing 10% PVP [polyvinylpyrrolidone], to
           slow down sperm movement, facilitating selection of morphologi-
           cally normal sperm for injection. This also minimizes sperm ad-
           herence to the glass surface once it is inside the micropipette. ….
           A sperm is immobilised by gently rubbing its tail on the bottom of
           the dish and aspirated into the pipette, tail first… Once the oocyte
           is brought into focus, the ICSI micropipette containing the immo-
           bilized sperm is lowered and brought into focus; once again, the
           fluid control and sperm movement within the pipette are assessed.
           Should the sperm become stuck in the pipette, it is expelled and
           another sperm is retrieved, or if necessary the microtool is chan-
           ged.
                The holding pipette is lowered and the oocyte is rotated so
           that a slit opening in the zona pellucida is at the 3 o’clock position.
           The outer edge of the oocyte is brought into focus and the sperm
           is brought to the tip of the micropipette. The micropipette is guid-
           ed through the slit opening in the zona pellucida into the center of
           the oocyte, and a small amount of ooplasm is aspirated into the
           micropipette to ensure breakage of the membrane by slow turning
           of the micrometer of the microinjector. Once the membrane has
           been broken, the contents of the micropipette, i.e. ooplasm and
           the immobilised sperm, are expelled slowly into the oocyte and the
           micropipette is slowly withdrawn. Complete control over aspira-
           tion and expulsion are needed to diminish the amount of medium
           deposited along with the sperm (Verlinsky and Kuliev 2005, 22).

    As is evident from this technical description of ICSI, fertilization in
the context of assisted conception is not narrated as a journey, an adven-
ture-romance, or an epic quest, but as a difficult feat of manual control of
tiny glass tools. Thus, although the ICSI penetration scene is legible as an
analogy to ‘normal’ fertilization, the procedure is clearly quite different in
terms of both form and content. Indeed, other than the fact that a sperm
ends up inside an egg, almost nothing about the means of achieving this
legendary union is analogous to the conventional narrative of the biologi-
cal union of egg and sperm. Indeed, as in the case of IVF, for which arti-
ficial menopause is the counter-intuitive ground state required of the fe-
male patient, ICSI is in many respects the opposite of its unassisted corol-
lary. Far from being an all but automatic natural process ensuring the
flow of reproductive substance across the generations, ICSI imagery de-
picts a skilled manual feat of precision micro-engineering to achieve suc-
cessful fertilization. Deliberately prevented from being either self-acting
or automatic, the egg and sperm are forced into a microtooled union via
manual assemblage. Formerly imagined as unstoppable, the sperm cell is
firmly taken in hand by the micro-manipulator: first it is ‘immobilized’,
then immersed in ooplasm, and ‘expelled’ into the egg – its tail having
been cut off to make it more easily manageable and ‘cleaner’. No longer a
38                                                            Tecnoscienza - 4 (1)

heroic gamete-Olympian, the sperm must be brought under ‘complete
control’. The only active agent in this union is the handler.
    What is just like ‘normal’ conception in the context of ICSI remains
its purpose, namely the unification of egg and sperm – thus activating the
process of fertilization leading to potential biological offspring. It is only
from the point of view of ensuring the continuity of biological relations
between parents and offspring that the logic of ICSI is identical to that of
‘unassisted’ conception. It is the aim of reproducing the familiar kinship
pattern of bilateral descent, through which the offspring inherits an equal
amount of shared substance from both parents, that drives this manual
imitation of a biological union. And it is precisely the fact that this union
did not occur naturally that makes the technological ‘seconding’ of this
process appear commonsensical. Reversing the usual logic, according to
which it is the biological facts of life that determine parenthood, ICSI is
only isomorphic with the standard model of ‘unassisted’ conception if bi-
ological action is superseded by the very logic it is imagined to underpin.
Consequently, it is a different union to that of the natural, biological
merging of egg and sperm which defines the visual and technical logics of
these images, namely the merging or fusion of substance and tool, or
hand and cell. The ICSI coupling, it turns out, is comprised of several in-
ter-related pairs: egg and sperm, camera and screen, tool and hand, view-
er and manipulator, and substance and tool. The reproduction of this
screen scene via the mainstream media adds yet another level to the dis-
tinctive visual logic of these images too, as it is the images themselves that
come to comprise a kind of shared cultural frame of reference for wit-
nessing the remaking of sex – or even a shared culture medium for under-
standing them. This layering of techno-logics – whereby ICSI might be
viewed on television, for example, or downloaded onto an iPhone – in
turn introduces a new convention of witnessing the ‘exact mechanisms’ of
reproduction live on screen.
    What is on display in such a spectacle is thus not only the logic of
IVF, but the biological relativity implicit in making biological relatives.
The relativity of the biological to the technical could hardly be made
more explicitly visual than in the scene of microinjection, in which cells
and tools engage in the complex intercourse of merging with a purpose.
Beyond the frame, beyond the invisible hands, beyond the camera and its
monitor, beyond the lab are all of the other important contextual ele-
ments through which this novel composition makes sense – such as the
conventional understanding of what a parent should be, as well as the ex-
pectation of what technology can do, and the logic that puts these two
forms of conventional thinking together to come up with ICSI as the ob-
vious answer. But like IVF, the sense this equation makes may be superfi-
cially obvious in ways that obscure what is implicitly contradictory and
even queer about its origins. For in addition to everything legible and or-
dinary about the logics of biology, kinship, reproduction, technology,
progress, and hope (among others) are the counter-logics the ICSI primal
Franklin                                                                   39
scene has the potential to suggest or imply – such as the fact that the dif-
ference between cells and tools has become irrelevant.


4. Conclusions
    It is in the convergence between the prevailing logics and conventions
of biological kinship and those introduced by new reproductive technol-
ogies that IVF, ICSI and their ilk that confirm a new relativity of the bio-
logical that remains to be charted as the “age of biology” unfolds. There
is no reason not to assume that the remaking of nature as technique will
remain largely compatible with the logics of unassisted nature, or natural
procreation, or of the ‘automatic’ flow of genealogy – nature has long
been cultured up, after all, and biology has arguably always been a rela-
tive condition. Moreover, nature and biology are highly plastic categories,
and as kinship theory confirms, biological parenthood has never been left
to its own devices. To the contrary, the logic by which biological parent-
hood is understood to create a natural tie, or a biological relation, is high-
ly dependent on specific forms of labour, including the crafting of sub-
stantial connections, family norms, kinship systems, inheritance patterns,
marriage prohibitions, and other social technologies.
    The way in which these new dimensions of reproductive experience
stretch the frame of existing conventions is both paralleled and demon-
strated in the imagery that has accompanied the rise of IVF over the past
thirty years, and specifically the rise of micromanipulation imagery, in its
very explicit staging of the mechanization of reproductive substance. If
micromanipulation has become an increasingly recognizable visual short-
hand for the fusion of tool and substance, and if ICSI introduces a new
figuration of conception that is more strongly defined in visual terms than
in narrative ones, what are the consequences of these shifts for under-
standings of ‘the facts of life’? Or with what we might call IVF? How do
these new images interact with older, more established, representations of
reproductive substance, such as the traditional egg and sperm narrative?
How do they refigure the meanings of the biological, the technological, or
the relationship of reproductive biology to new forms of digital represen-
tation? To understand the formation of an emergent global biological cul-
ture, and to interpret the ways in which IVF works not only as a technol-
ogy of reproduction, but a culture medium, IVF is an excellent case study
that will repay further investigation.
    One defining feature of the imagery of retooled reproductive sub-
stance is its introduction of a new genealogical model, in which it is not
only reproductive substance, but its directionality, orientation or ‘flow’
that is redesigned. In the familiar tree models of natural history, so fa-
voured by Darwin, and still a basic tool of genetics today, reproductive
flow is always one-way. It is also always brachiating, binary, and bilateral,
but contained, and limited, in its irrevocable path. This arboreal pattern
40                                                            Tecnoscienza - 4 (1)

of biological flow is superseded in micromanipulation images both by
new conduits for the transmission, in the form of the tools, and the possi-
bility of open-ended dissemination. These are the new coordinates of mi-
cromanipulated life. Extending beyond the frame, the micro-tools point
not only to the genealogical terminus that is their object, but to the termi-
nation of the conventional genealogical model (so familiar to kinship
studies) that was their predecessor. The rotation of its regenerative axis to
a horizontal position re-orients the genealogy of flat screen life, while de-
taching this scene from it from its genealogical ‘trunk’, and leaving it lit-
erally open-ended as a conduit. The new ‘stem’ of life in the flat screen
world of cultivated human cells is the inner cell mass – the totipotent
source of cells that can be amplified into regenerative lines. In the context
of flat screen life, genealogy is an open-door.
     The visual grammar that holds the micro-manipulation image in place,
then, is not derived from the logic of sex or genealogy belonging to natu-
ral history, but rather to modern scientific technique. It might be difficult
to find a more explicit visual representation of Rabinow’s (1992) claim
that life “will become technique” in a manner that reverses the order of
Darwinian evolutionary time and telos, by making culture the origin of
biology. The fact that the cells on the bed of the micro-manipulator are
submerged in culture medium reminds us of the etymological roots of the
term ‘culture’ in cultivation, that is, in the art of technique. What mi-
cromanipulation imagery provides is the kind of horizon-altering perspec-
tival shift described by Barbara Duden (1993) in relation to fetal photog-
raphy – offering an instrumental reframing of reproduction as technology.
This is how micromanipulation imagery has become, in Duden’s words,
“part of the mental universe of our time” (1993, 1) in its depiction of the
production of new life in ways that are detached from the orders and
logics of living things that have structured far more than biological cate-
gories in the past.
     It is the relativity of these former biological categories that IVF argua-
bly makes more visible – both in its use as a clinical procedure, and as a
research tool in science. To describe IVF as a technological platform has
a literal meaning in relation to micromanipulation imagery that is both
technically and metaphorically apt (as is the common description of the
micromanipulation table as its ‘bed’). The mental universe in which both
IVF and flat screen life are legible – their grammar – is increasingly wide-
ly shared, and help to contextualize the question of why IVF is so popular
in spite of all its difficulty, and why it is so curious despite having become
more regular and normal. The same logic that makes IVF useful for clini-
cal purposes – as a tool to aid in the overcoming of the obstacle of infer-
tility – applies to the remaking of biology as technology more generally,
and thus also to the newly conventional visual logic of micromanipula-
tion, with its vivid depiction of taking living tools in hand. To the extent
this logic also grounds a new understanding of technology as biology,
Franklin                                                                         41
through the recomposition of reproductive substance, so too has it al-
ready reshaped the future of kinship.


References
Anker, S. and Franklin, S. (2011) Specimens as Spectacles: Reframing Fetal Re-
   mains, in “Social Text”, 29 (1), pp. 103-125.
Brand, S. (2010) Whole Earth Discipline, London, Atlantic Books.
Cartwright, L. (1995) Screening the Body: Tracing Medicine’s Visual Culture, Min-
   neapolis, MN, University of Minnesota Press.
Cosgrove, D. (2001) Apollo’s Eye: a Cartographic Genealogy of the Earth in the
   Western Imagination, Baltimore, MD, John’s Hopkins University Press.
Dubow, S. (2009) Ourselves Unborn: A History of the Fetus in Modern America,
  Oxford, Oxford University Press.
Duden, B. (1993) Disembodying Women: Perspectives on Pregnancy and the Un-
  born, Cambridge, MA, Harvard University Press.
Foucault, M. (1976) La volonté du savoir, Paris, Gallimard (Eng. transl. The His-
   tory of Sexuality. Volume 1: An Introduction, New York, Vintage, 1990).
Franklin, S. (1991) Fetal Fascinations: New Dimensions to the Medical Scientific
   Construction of Fetal Personhood, in S. Franklin, J. Stacey and C. Lury (eds.)
   Off-Centre: Feminism and Cultural Studies, London, Harper Collins, pp. 190-
   205.
Franklin, S. (1997) Embodied Progress: a Cultural Account of Assisted Conception,
   London, Routledge.
Franklin, S. (1999) Dead Embryos: Feminism in Suspension, in L. M. Morgan and
   M. W. Michaels (eds.) Fetal Subjects, Feminist Positions, Philadelphia, Univer-
   sity of Pennsylvania Press, pp. 61–82.
Franklin, S. (2003) Re-thinking Nature-Culture: Anthropology and the New Genet-
   ics, in “Anthropological Theory”, 3 (1), pp. 65-85.
Franklin, S. (2004) Stem Cells R Us: Emergent life Forms and the Global Biologi-
   cal, in A. Ong and S. J. Collier (eds.) Global Assemblages: Technology, Politics
   and Ethics as Anthropological problems, Oxford, Blackwell, pp. 59-78.
Franklin, S. (2013) Biological Relatives: IVF, Stem Cells and the Future of Kinship,
   Durham, NC, Duke University Press.
Franklin, S., Lury, C. and Stacey, J. (eds.) (2000) Global Nature, Global Culture,
   London, Sage.
Hacking, I. (1983) Representing and Intervening, Cambridge, Cambridge Univer-
   sity Press.
Haldane, J. B. S. (1924) Daedalus: or, Science and the Future, New York, E. P.
   Dutton and Company.
42                                                                 Tecnoscienza - 4 (1)

Hartouni, V. (1992) Fetal Exposures: Abortion Politics and the Optics of Allusion,
   in “Camera Obscura”, 10 (2 29), pp. 130-149.
Hopwood, N. (1999) Giving Body’ to Embryos: Modeling, Mechanism and the Mi-
  crotome in Late Nineteenth-Century Anatomy, in “Isis” 90 (3), pp. 462–496.
Hopwood, N. (2000) Producing Development: The Anatomy of Human Embryos
  and the Norms of Wilhelm His, in “Bulletin of the History of Medicine”, 74
  (1), pp. 29–79.
Hopwood, N. (2009) Embryology, in P. J. Bowler and J. V. Pickstone (eds.) The
  Cambridge History of Science, Vol. 6: The Modern Biological and Earth Scienc-
  es, Cambridge, Cambridge University Press, pp. 285-315.
Kaplan, E. A. (1994) Look Who’s Talking, Indeed: Fetal Images in Recent North
   American Visual Culture, in E. N. Glenn, G. Chang, and L. R. Forcey (eds.),
   Mothering: Ideology, Experience, and Agency, New York, Routledge, pp. 121-
   137.
Keller, E. F. (1996) The Biological Gaze, in G. Robertson, M. Mash, L. Tickner, J.
    Bird, B. Curtis and T. Putnam (eds.) FutureNatural: Nature, Science, Culture,
    London and New York, Routledge, pp. 107-121.
Kelley, K. W. (ed.) (1988) The Home Planet, Reading, MA, Addison-Wesley.
Landecker, H. (2006) Microcinematography and the History of Science and Film, in
   “Isis”, 97 (1), pp. 121-132.
Landecker, H. (2007) Culturing Life: How Cells Became Technologies, Cambridge,
   MA, Harvard University Press.
Lie, M. (2012) Reproductive Images: The Autonomous Cell, in “Science as Cul-
    ture”, 21 (4), pp. 475-496.
Loeb, J. (1913) Reversibility in Artificial Parthenogenesis, in “Science, S. N.”, 38,
   pp. 749-750.
Macnaghten, P. and Urry, J. (1995) Towards a Sociology of Nature, in “Sociology”,
   29, pp. 203-20.
Michaels, M. W. (1999) Fetal Galaxies: Some Questions About What We See, in L.
   M. Morgan and M. W. Michaels (eds.) Fetal Subjects, Feminist Positions, Phil-
   adelphia, University of Pennsylvania Press, pp. 113-32.
Martin, E. (1991) The Egg and the Sperm: How Science has Constructed a Romance
   Based on Stereotypical Male and Female Roles, in “Signs” 16 (3), pp. 485-501.
Morgan, L. (2009) Icons of Life: a Cultural history of Human Embryos, Berkeley,
  University of California Press.
Newman, K. (1996) Fetal Positions: Individualism, Science, Visuality, Stanford,
  CA, Stanford University Press.
Petchesky, R. P. (1987) Foetal Images: The Power of Visual Culture in the Politics
   of Reproduction, in M. Stanworth (ed.) Reproductive Technologies: Gender,
   Motherhood and Medicine, Cambridge, Polity, pp. 57-80.
Franklin                                                                        43
Pauly, P. J. (1987) Controlling Life: Jacques Loeb and the Engineering Ideal in Bi-
   ology, Oxford, Oxford University Press.
Poole, R. (2008) Earthrise: How Man First Saw the Earth, New Haven, CT, Yale
   University Press.
Rabinow, P. (1992) Artificiality and Enlightenment, in J. Crary and S. Kwinter
   (eds.) Incorporations, New York, Zone Books, pp. 234-52.
Squier, S. M. (1994) Babies in Bottles: Twentieth Century Visions of Reproductive
        Technology, New Brunswick, NJ, Rutgers University Press.
Stabile, C. (1992) Shooting the Mother: Fetal Photography and the Politics of Dis-
        appearance, in “Camera Obscura”, 10 (1 28), pp. 178-205.
Strathern, M. (1992a) After Nature: English Kinship in the Late Twentieth Centu-
        ry, Cambridge, Cambridge University Press.
Strathern, M. (1992b) Reproducing the Future: Anthropology, Kinship and the
        New Reproductive Technologies, New York, Routledge.
Traweek, S. (1988) Beamtimes and Lifetimes: The World of high Energy Physicists,
      Cambridge, MA, Harvard University Press.
Verlinsky, Y. and Kuliev, A. (2005) Atlas of Preimplantation Genetic Diagnosis,
       London, CRC Press.
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