what genes affect wilms tumors
This page Mutations of the WT1 gene on chromosome 11p13 are observed in approximately 20% of Wilms tumors. At least half of the Wilms tumors with mutations in WT1 also carry mutations in CTNNB1, the gene encoding the proto-oncogene beta-catenin. A gene on the X chromosome, WTX, is inactivated in up to 30% of Wilms tumor cases, according to research published in 2007. Most cases do not have mutations in any of these genes.