what causes increased alkaline phosphatase level
- The alkaline phosphatase test (ALP) is used to help detect liver disease or bone disorders. 1  In conditions affecting the liver, damaged liver cells release increased amounts of ALP into the blood.2  Any condition that affects bone growth or causes increased activity of bone cells can affect ALP levels in the blood.f ALP results are increased but it is not clear whether this is due to liver or bone disease, tests for ALP isoenzyme may be done to determine the cause. A GGT test and/or a test for 5'-nucleotidase may also be done to differentiate between liver and bone disease.