pigment epithelial detachment causes
What does pigment epithelial detachment (PED) involve? Follow Following Unfollow Pending Disabled. A answered. Pigment epithelial detachment (PED) is a manifestation of neovascular (wet) age-related macular degeneration (AMD). There are different forms of PED, and some have a better prognosis than others, but unfortunately, all forms of PED can cause progressive visual loss. Retinal pigment epithelial detachment. Detachment of the retinal pigment epithelium may or may not be associated with choroidal neovascularization and may be caused by different types of pathogenesis, each associated with distinct angiographic features, natural course, visual prognosis, and response to treatment.