one major difference between meiosis i and meiosis ii is that
- The essential difference between meiosis I and meiosis II is in purpose. Meiosis I is dedicated to forming two haploid cells from one diploid cell, while meiosis II is meant to split the sister chromatids in the haploid cells produced in meiosis I, creating four daughter cells. Meiosis I also recombines, or shuffles, genes on each pair of chromosomes.