early signs of thyroid problems
- You might not notice signs or symptoms of Hashimoto's disease at first, or you may notice a swelling at the front of your throat (goiter). Hashimoto's disease typically progresses slowly over years and causes chronic thyroid damage, leading to a drop in thyroid hormone levels in your blood.igns and symptoms of hypothyroidism include: 1  Fatigue and sluggishness. 2  Increased sensitivity to cold. 3  Constipation. 4  Pale, dry skin. 5  A puffy face. 6  Hoarse voice. 7  Unexplained weight gain â occurring infrequently and rarely exceeding 10 to 20 pounds, most of which is fluid.