The drinking water assessment provides Tier II (PRZM 3.12/EXAMS 2.98)
surface water modeling and Tier I (SCI-GROW, version 2.3) groundwater
modeling.  The modeling was conducted for the parent compound only.  The
residue concentrations from Tier II surface water modeling are not
expected to exceed 35.6 µg/L for the peak concentration, 2.3 µg/L for
the annual average concentration, and 1.5 µg/L for the 30 year average
concentration.  Residue concentration from Tier I groundwater modeling
is not expected to exceed 0.02 µg/L.  For acute exposures the 35.6
µg/L peak concentration was used.  For chronic exposures the 2.3 µg/L
annual average concentration was used.  These drinking water residues
were incorporated in the DEEM-FCID into the food categories “water,
direct, all sources” and “water, indirect, all sources.”

Residue Data Used for Acute and Chronic Assessments

For the acute dietary analysis, tolerance level or highest field trial
residues were used for all crops.  The crops for which the highest field
trial residues were used are as follows: Amaranth, leafy; Arugula;
Chrysanthemum; Cress, garden; Cress, upland; Dandelion, leaves; Fennel;
Parsley, leaves; Radicchio; Rhubarb; Spinach; Swiss chard; Beans, dry;
Celery; Lettuce, head; Lettuce, leaf; and Pea, dry.  One hundred percent
crop treated was assumed for all commodities in the assessment. For the
chronic dietary analysis, anticipated residues were derived for certain
crops (apple, broccoli, celery, collard, grape, lettuce, citrus, pepper,
mustard green and tomato), which are the major dietary contributors
based on preliminary runs. Experimentally derived processing factors for
apple juice, grape juice, citrus juices, tomato paste, tomato puree,
wheat flour, and wheat germ were applied.

Results of Acute Dietary Exposure Analysis

The results of the aggregate acute dietary analysis for food and water
indicate that acute dietary risks do not exceed Agency’s level of
concern (< 100% of the aPAD) for the U.S. population and all subgroups.
At the 95th percentile, the U.S. population has an exposure from food
and drinking water that results in a risk estimate for the general U.S.
population at 1% of the aPAD.  The most highly exposed subpopulation is
“females 13-49 years” at 80% of the aPAD.  The results of the acute
dietary exposure analysis at the 95th percentile of exposure are
reported in Table 15 below.

Results of Chronic Dietary Exposure Analysis

The results of the aggregate chronic dietary analysis for food and
drinking water indicate that chronic dietary risks (food and drinking
water) do not exceed HED’s level of concern (<100% cPAD) for the U.S.
population and all subgroups.  The U.S. population exposure from food
and water results in a risk estimated at 19% of the cPAD.  The most
highly exposed population subgroup is “children 1 -2” with an
exposure estimated at 48% of the cPAD.  The results of the chronic
dietary exposure analysis are reported in Table 15, below.

Table 15.  Summary of Dietary Exposure and Risk for Pyraclostrobin –
Food & Water

Population Subgroup	Acute Dietary

(95th Percentile)	Chronic Dietary	Cancer

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure

(mg/kg/day)	% cPAD	Dietary Exposure

(mg/kg/day)	Risk

General U.S. Population	0.043	1.4	0.0061	19	A separate quantitative
cancer risk assessment is not required.

All Infants (< 1 year old)	0.055	1.8	0.011	33

	Children 1-2 years old	0.072	2.4	0.016	48

	Children 3-5 years old	0.064	2.2	0.012	36

	Children 6-12 years old	0.046	1.5	0.0074	22

	Youth 13-19 years old	0.035	1.2	0.0043	13

	Adults 20-49 years old	0.039	1.3	0.0050	15

	Adults 50+ years old	0.041	1.4	0.0057	17

	Females 13-49 years old	0.040	80	0.0047	14

Conclusions

Acute and chronic exposures and risks do not exceed HED’s level of
concern for the U.S. population and for all relevant population
subgroups.  Since risk estimates are below HED’s level of concern, a
more highly refined analysis is not needed at this time.  Of note is
that contribution from drinking water is minimal.  HED concludes that
the acute and chronic exposure estimates are unlikely to underestimate
actual acute or chronic exposure.

5.3	Anticipated Residue and Percent Crop Treated (%CT) Information TC
\l2 "5.3 Anticipated Residue and Percent Crop Treated (%CT) Information

The acute analysis was conducted using tolerance level residues or the
highest residues for all commodities. These tolerance level or highest
residues were derived from field trial data conducted at the maximum
application rate and minimum PHI permitted on the proposed or existing
labels.  For all commodities 100% crop treated was assumed.  A limited
number of experimentally derived processing factors were used to refine
the acute and chronic analyses.

The chronic dietary assessment was conducted using tolerance level
residues for all crops except for apple, celery, grape, head lettuce,
leaf lettuce, orange, pepper, spinach, tomato and additional crops in
the leafy vegetables group where anticipated average residue values were
derived from crop field trials.  These field trials represent maximum
application rates and minimum PHIs.  For all commodities 100% crop
treated was assumed.

6.0	Residential (Non-Occupational) Exposure/Risk Characterization  TC
\l1 "6.0	Residential (Non-Occupational) Exposure/Risk Characterization

A product containing pyraclostrobin (i.e., Insignia®) is registered for
application to residential turf grass and recreational sites.  It may be
applied to turf at rates ranging from 0.28 to 0.5 lb ai/A, at intervals
of 14 to 28 days; and the maximum seasonal application rate is 3 lb
ai/A.  The residential exposure assessment was prepared in an HED
memorandum dated 8/19/04 (D298017, K. O’Rourke).  Residential and
recreational turf applications are applied by professional pest control
operators (PCOs) only, and therefore, residential handler exposures do
not occur.  There is, however, a potential for exposure to homeowners in
residential settings from entering previously treated lawns where
children might play and adults might work or play.  As a result, risk
assessments have been completed for postapplication scenarios.  The
short-term MOEs for each postapplication scenario resulted in MOEs above
100, and therefore are not of concern.  For toddlers, the short-term
dermal MOE is 180 (0.027 mg/kg/day) and the combined incidental oral MOE
is 620 (0.009425 mg/kg/day; hand-to-mouth activities), and combined
dermal and oral exposures result in and MOE of 140.  Dermal and
incidental oral exposures are combined because they share common toxic
effects; i.e., decreased body weight gain and decreased food
intake/efficiency.  For adults, the short-term dermal MOE is 260 (0.019
mg/kg/day).

Recreational exposures to turf are expected to be similar to, or in many
cases less than, those evaluated for residential postapplication
exposure and risk; and therefore, a separate recreational exposure
assessment was not conducted.

Spray drift is always a potential source of exposure to residents nearby
to spraying operations.  This is particularly the case with aerial
application, but, to a lesser extent, could also be a potential source
of exposure from the ground application method employed for
pyraclostrobin.  The Agency has been working with the Spray Drift Task
Force, EPA Regional Offices and State Lead Agencies for pesticide
regulation and other parties to develop the best spray drift management
practices.  The Agency is now requiring interim mitigation measures for
aerial applications that must be placed on product labels/labeling.  The
Agency has completed its evaluation of the new data base submitted by
the Spray Drift Task Force, a membership of U.S. pesticide registrants,
and is developing a policy on how to appropriately apply the data and
the AgDRIFT computer model to its risk assessments for pesticides
applied by air, orchard airblast and ground hydraulic methods.  After
the policy is in place, the Agency may impose further refinements in
spray drift management practices to reduce off-target drift and risks
associated with aerial as well as other application types where
appropriate.

7.0	Aggregate Risk Assessments and Risk Characterization  TC \l1 "7.0
Aggregate Risk Assessments and Risk Characterization

In accordance with the FQPA, HED must consider and aggregate (add)
pesticide exposures and risks from three major sources: food, drinking
water, and residential exposures.  In an aggregate assessment, exposures
from relevant sources are added together and compared to quantitative
estimates of hazard (e.g., a NOAEL or PAD), or the risks themselves can
be aggregated.  When aggregating exposures from various sources, HED
considers both the route and duration of exposure.  Common effects
(i.e., decreased body weight gain, food intake, and food efficiency)
were seen in the studies selected to evaluate dietary, dermal and
incidental oral ingestion exposures; and therefore, route-specific
exposures can be aggregated.

Based on the proposed Section 3 food crop uses, aggregate assessments
were conducted for acute and chronic dietary exposures (food + drinking
water), and existing short-/intermediate-term residential exposures
(i.e., chronic dietary, plus incidental oral and dermal exposures for
kids, and chronic dietary, plus dermal exposures for adults).  Both
short- and intermediate-term exposures may occur during postapplication
activities for adults and children.  However, because the toxicity
endpoints and points of departure are identical for short- and
intermediate-term exposures, separate risk estimates for short- and
intermediate-term exposures were not calculated.

To assess aggregate acute and chronic dietary risks, estimates of
pesticide residues in drinking water (EDWCs) were incorporated directly
into the dietary exposure analysis.  Refer to section 5.2 for these risk
estimates.

The short-/intermediate-term aggregate risk assessment takes into
account average exposure estimates from dietary consumption of
pyraclostrobin (food and drinking water) and
non-occupational/residential uses (turf).  Postapplication exposures
from the use on turf are considered predominantly short-term (1-30
days).  To calculate the short-/intermediate-term aggregate risk
estimates, the chronic dietary exposure (food + drinking water) is added
to the residential exposures using the inverse MOE methodology described
below (see Table 16 below).  The total combined MOE from dietary (food +
water) and non-occupational/residential exposure is 100 for children 1-2
years old, which is not of concern to HED.  For adults the total
combined MOE is 200, which also is not of concern to HED.  These
aggregate exposure risk assessments are considered conservative
estimates, that should not underestimate risks, because of the following
inputs: 1) dietary inputs primarily used tolerance level residues; 2)
crop specific (turf) screening level drinking water modeling data were
used (i.e., Tier II surface water model); 3) maximum application rates
and minimum application intervals were used; and 4) conservative SOPs
and upper level estimates of exposure were employed.

Table 16.  Short-/Intermediate Term Aggregate Risk Calculations

Population

Dermal Exposure

Oral Exposure

Total Combined MOE2

NOAEL

mg/kg/day

Exposure

mg/kg/day

MOE1

NOAEL mg/kg/day

Incidental Oral Exposure mg/kg/day 	Chronic Dietary (Food + Water)
mg/kg/day

MOE1

Children 1-2 yrs

5

0.027

180

5.8

0.009425

0.0164

220

100

Adults

5

0.019

260

5

NA

0.00613

820

200

1 The Level of Concern MOE is 100.

2 Total Combined MOE = 1/ [(1/MOEDermal) + (1/MOEOral)]

8.0	Cumulative Risk Characterization/Assessment  TC \l1 "8.0	Cumulative
Risk Characterization/Assessment

Unlike other pesticides for which EPA has followed a cumulative risk
approach based on a common mechanism of toxicity, EPA has not made a
common mechanism of toxicity finding as to pyraclostrobin and any other
substances and pyraclostrobin does not appear to produce a toxic
metabolite produced by other substances. For the purposes of this
tolerance action, therefore, EPA has not assumed that pyraclostrobin has
a common mechanism of toxicity with other substances. For information
regarding EPA’s efforts to determine which chemicals have a common
mechanism of toxicity and to evaluate the cumulative effects of such
chemicals, see the policy statements released by EPA’s Office of
Pesticide Programs concerning common mechanism determinations and
procedures for cumulating effects from substances found to have a common
mechanism on EPA’s website at   HYPERLINK
"http://www.epa.gov/pesticides/cumulative/"
http://www.epa.gov/pesticides/cumulative/ .

9.0	Occupational Exposure/Risk Pathway  TC \l1 "9.0	Occupational
Exposure/Risk Pathway

Reference: Pyraclostrobin: Occupational and Residential Risk Assessment
to Support Request for Section 3 Registrations on Oats and Oilseed Crop
group (Foliar and Seed Treatment), Herbs, and Tropical Fruits. (DP#:
348792; PC#: 099100) K. O’Rourke; 01/31/08.

9.1	Short-/Intermediate-Term Handler Risk  TC \l2 "9.1
Short-/Intermediate-Term Handler Risk

Foliar and In-Furrow Treatment

Occupational handlers may experience short-/intermediate-term exposure
to pyraclostrobin while mixing/loading and applying sprays to
agricultural crops.  No chemical-specific handler exposure data were
submitted in support of this use pattern.  It is the policy of the HED
to use data from the Pesticide Handlers Exposure Database (PHED) Version
1.1 as presented in PHED Surrogate Exposure Guide (8/98) to assess
handler exposures when chemical-specific monitoring data are not
available ( HED Science Advisory Council for Exposure Draft Policy # 7,
dated 1/28/99).

The results of the occupational handler exposure and risk assessment
indicate that risks are not of concern with baseline clothing, or in
some cases, when gloves and respirator are used to mitigate exposure.
[Note: The respirator unit exposure value represents a PF 5
NIOSH-approved filtering face-piece respirator (e.g., dust mask), which
is considered to provide an 80% reduction in inhalation exposure.]
Exposure assumptions and MOE estimates are summarized in Table 17.

It is feasible for the same individual to mix/load and apply
formulations, especially for groundboom and airblast applications,
however, appropriate data are not available in PHED for which unit
exposures for these combined activities can be derived.  HED does not
recommend simply adding the unit exposure values for each job function
because any extrapolation error (i.e., exposure from the amount ai
handled in the study to that of a real-life application) would be
magnified, leading to greater uncertainty.  For information and
characterization purposes, even with the over-estimation uncertainty,
the MOEs for these combined activities for groundboom and airblast
application of pyraclostrobin would be above the LOC of 100, and not of
concern (i.e., dermal/inhalation MOEs of 1,400/210 and 1,200/510,
respectively).

The proposed Headline® Fungicide label requires chemical resistant
gloves, however, a respirator is not indicated.  In addition, the
minimum level of PPE for handlers is based on acute toxicity for the
end-use products.  The Registration Division (RD) is responsible for
ensuring that PPE listed on the label is in compliance with the Worker
Protection Standard (WPS).

	Table 17.  Summary of  MOEs for Occupational Handlers of Pyraclostrobin
(Foliar Treatment)

Exposure Scenario (Scenario #)	Dermal Unit Exposure (mg/lb ai) 1
Inhalation

Unit

Exposure

(mg/lb ai) 1	Use Site	Application

Rate

(lb ai/A) 2	Area Treated

(A/day) 3	Daily Dose

(mg/kg/day) 4	Short-/Int-term

MOE 5

Dermal	Inhalation	Dermal	Inhalation

Mixer/Loader

(1) Mixing/Loading Liquid for Aerial application or Chemigation	2.9

or

0.023

(w/gloves)	0.0012

or

0.00024

(w/

respirator)

	Oats	0.15	1,200	1.2

0.0097

(gloves)	0.0031

0.00062

(respirator)	4.1

520

(gloves)	75

370

(respirator)

	Canola & Flax	0.10	350	0.24

0.0019

(gloves)	0.00060	21

2,700

(gloves)	380

(2) Mixing/Loading Liquid for Groundboom application or Chemigation

	In-Furrow tmt	0.20	200	0.27

0.0021

(gloves)	0.00069	18

2,300

(gloves)	340

	Oats	0.15	200	0.20

0.0016

(gloves)	0.00051	25

3,100

(gloves)	450

	Canola & Flax	0.10	80	0.054

0.00043

(gloves)	0.00014	92

12,000

(gloves)	1,700

(3) Mixing/Loading Dry Flowables for Aerial application or Chemigation
0.066	0.00077	Turf & Ornamentals	0.50	350	0.027	0.0019	190	120

	Herbs & Tropical Fruit	0.15	350	0.0081	0.00058	620	400

(4) Mixing/Loading Dry Flowables for Groundboom application

	Herbs	0.15	80	0.0018	0.00013	2,700	1,700

(5) Mixing/Loading Dry Flowables for Airblast application

	Tropical Fruit	0.15	40	0.00092	0.000066	5,400	3,500

Applicator

(6) Applying Sprays with Fixed-wing Aircraft	0.005	0.000068	Turf &
Ornamentals	0.50	350	0.0020	0.00017	2,400	1,400

	Oats	0.15	1,200	0.0021	0.00017	2,400	1,300

	Herbs & Tropical Fruit	0.15	350	0.00061	0.000051	8,200	4,500

	Canola & Flax	0.10	350	0.00041	0.000034	12,000	6,800

(7) Applying Sprays with Open Cab Groundboom 	0.014	0.00074	In-Furrow
tmt	0.20	200	0.0013	0.00042	3,800	540

	Oats	0.15	200	0.00098	0.00032	5,100	730

	Herbs	0.15	80	0.00039	0.00013	13,000	1,800

	Canola & Flax	0.10	80	0.00026	0.000085	19,000	2,700

(8) Applying Sprays with Open Cab Airblast Sprayer	0.36	0.0045	Tropical
Fruit	0.15	40	0.0050	0.00039	990	600

Flagger

(9) Flagging to Support Aerial Applications	0.011	0.00035	Turf &
Ornamentals	0.50	350	0.0045	0.00088	1,100	260

	Oats, Herbs & Tropical Fruit	0.15	350	0.0013	0.00026	3,700	880

	Canola & Flax	0.10	350	0.00090	0.00018	5,600	1,300

1 Dermal unit exposure values represent long pants, long sleeved shirts,
shoes, and socks; values representing the addition of chemical-resistant
gloves are shown for those scenarios in which the MOEs do not reach 100
at baseline.  Inhalation unit exposure values represent no respirator,
except for “Oats” in Scenario #1, for which a dust-mist respirator
was added.  Values are reported in the PHED Surrogate Exposure Guide
dated August 1998.

2 Application rates are based on maximum values found in proposed labels
(See Table 1)

3 Daily area treated is based on the area that can be reasonably applied
in a single day for each exposure scenario, based on the application
method and formulation/packaging type. (standard EPA/OPP/HED values).

4 Daily Dose (mg/kg/day) = (Unit Exposure * % Absorption * Application
rate * Area treated) / Body Weight of 60-kg for dermal or 70-kg for
inhalation; where dermal absorption is 14%..

5 Short-/Intermediate-Term MOE = NOAEL / Daily Dose.  The dermal NOAEL
is 5 mg/kg/day, and the inhalation NOAEL is 0.23 mg/kg/day.  The LOC is
100.

Seed Treatment

Occupational handlers may experience short-/intermediate-term exposure
to pyraclostrobin while performing seed treatment activities, including
several distinct handling activities, each with its own exposure
potential.  These activities are: (1) loader/applicator; (2) sewer; (3)
bagger; (4) multiple activities (including cleaning and forklift
operation); and, (5) seed planters.

No chemical-specific handler exposure data were submitted in support of
this use pattern.  For assessing seed treatment activities, unit
exposure data were taken from HED Science Advisory Council for Exposure
Policy 14: Standard Operating Procedures for Seed Treatment.  The amount
of ai handled depends on the application rate (lb ai/100 lb seed) and
the pounds of seed treated in a day (or the pounds of seed that can be
planted in a day), all of which may vary, depending upon the seed type.
Values for the amount of seed treated and planted per day were obtained
from HED’s Standard Operating Procedure (SOP) #15.  Exposure and risk
estimates for seed treatment handlers were calculated based on canola
data (commercial rate assumed to be 718,000 lb seed/day) for seed
treatment, and flax data for seed planting, which represent the maximum
combination of application rate and amount handled for the proposed
crops.  The results are presented in Table 18.

For the proposed seed treatment uses, all seed treatment activities
result in MOEs greater than the LOC of 100 with baseline clothing, or
baseline plus gloves and respirator, and therefore, are not of concern.
While there is a data gap for on-farm seed treatment (i.e., the data
available for on-farm seed treatment represents a dust formulation in a
planter box, which is not applicable) this scenario is not likely to
result in risks of concern because seed treatment activities in the
commercial setting (estimated in Table 18), which handle much greater
quantities of seed, are not of concern.  [Note: The respirator unit
exposure value represents a PF 5 NIOSH-approved filtering face-piece
respirator (e.g., dust mask), which is considered to provide an 80%
reduction in inhalation exposure.]

The proposed BAS 500 ST label is a supplemental label only, and does not
provide information regarding personal protective equipment (PPE) (i.e.,
whether gloves and a respirator are currently required).  In addition,
the minimum level of PPE for handlers is based on acute toxicity for the
end-use product.  The Registration Division (RD) is responsible for
ensuring that PPE listed on the label is in compliance with the Worker
Protection Standard (WPS).

Table 18.  Summary of  MOEs for Seed Treatment Activities

Activity	Dermal Unit Exposure (mg/lb ai) 1	Inhalation

Unit

Exposure

(mg/lb ai) 1	Application

Rate

(lb ai/

lb seed) 2	Seed Handled per Day

(lb seed) 3	Daily Dose

(mg/kg/day) 4	Short-/Int-term

MOE 5

	Dermal	Inhalation	Dermal	Inhalation

Loader/ Applicator	0.023

(w/gloves)	0.00034	0.0004	718,000	0.015	0.0014	320	160

Sewer	0.0062	0.00023

	0.0042	0.00094	1,200	240

Bagger	0.0091	0.00016

	0.0061	0.00066	820	350

Multiple

Activity	0.042

(w/gloves)	0.0016

or

0.00032

(w/respirator)

	0.028	0.0066

or

0.0013

(w/respirator)	180	35

or

180

(w/respirator)

On-Farm	No data	No data

6,700	--	--	--	--

Seed Planter	0.25

(w/gloves)	0.0034

	0.0016	0.00013	3,200	1,800

1 Dermal unit exposure values represent baseline clothing (long pants,
long sleeved shirts, shoes, and socks), except where gloves are
indicated (for planting, gloves are for loading only).  Inhalation unit
exposure values represent no respirator, except for “multiple
activity” scenario.  There is a data gap for on-farm seed treatment;
the formulation is a water-dispersible granule for which the label
indicates standard slurry or mist-type seed treatment equipment should
be used.  The data available for on-farm seed treatment represents a
dust formulation in a planter box scenario, which is not applicable.

2 Application rates are based on maximum values in proposed seed
treatment label (See Table 1)

3   SEQ CHAPTER \h \r 1 Values for amount of seed handled for all
activities are based on an assumed rate for canola, except the on-farm
and planter scenarios, which were based on flax.

4 Daily Dose (mg/kg/day) = (Unit Exposure * % Absorption * Application
rate * Seed Handled) / Body Weight of 60-kg for dermal or 70-kg for
inhalation; where dermal absorption is 14%.

5 Short-/Intermediate-Term MOE = NOAEL / Daily Dose.  The dermal NOAEL
is 5 mg/kg/day, and the inhalation NOAEL is 0.23 mg/kg/day.  The LOC is
100.

9.2	Short-/Intermediate-Term Postapplication Risk  TC \l2 "9.2
Short-/Intermediate-Term Postapplication Risk

This Section 3 action for pyraclostrobin involves foliar applications to
agricultural crops.  Therefore, postapplication exposure is possible for
workers entering treated fields.  Chemical-specific dislodgeable foliar
residue (DFR) data had previously been submitted by the registrant to
support earlier registration requests for food crops (MRID#s: 45118727,
45118724, 45118726, and 45118728 and 45118729).  An overview of each
study was provided in a previous assessment (D269670, K. O’Rourke,
9/30/2002); a summary of the results is provided in Table 19.

The DFR data were used to estimate restricted entry intervals (REIs) by
extrapolating, where possible, to the proposed crops.  It was found that
the type of formulation used influences the DFR profile; therefore, DFR
data for both the emulsifiable concentrate and water-dispersible granule
formulations were considered.  Average percent initial DFR values were
calculated (i.e., 18% for emulsifiable concentrate and 20% for
water-dispersible granule) and used to estimate surrogate residue values
for each crop, according to its proposed formulation.  Although
uncertainties are introduced into the assessment when crop-specific
residues are used to estimate residues for other types of crops, it is
believed to be more realistic than using default assumptions

In addition to these residue data, transfer coefficients (Tc) are used
to relate the foliage residues to activity patterns (e.g., scouting) to
estimate potential human exposure.  The transfer coefficients used in
this assessment are from an interim transfer coefficient policy
developed by HED’s Science Advisory Council for Exposure using
proprietary data from the Agricultural Re-entry Task Force (ARTF)
database (policy # 3.1).

The estimated short-/intermediate-term MOEs are presented in Table 20.
The results of the postapplication exposure and risk assessment indicate
that MOEs of 100 are achieved on Day 0 for all scenarios and, therefore,
are not of concern.

The pyraclostrobin technical material has been classified in Toxicity
Category III for acute dermal, primary eye irritation, and primary skin
irritation.  Per the Worker Protection Standard (WPS), a 12-hr
restricted entry interval (REI) is required for chemicals classified
under Toxicity Category III or IV.  The proposed labels indicate an REI
of 12 hrs, which is in compliance with the WPS.

Table 19.  Summary of DFR Study Results

Crop

Location

(state)

Formu-lation

Application Rate

(lb ai/A)

Number

of Apps.

Interval

r2

Initial DFR

(% of

Appl. Rate)

Dissipation

(% per day)

Half-life (days)

peaches

CA

WDG

0.12

5

7 days

0.84

22

2

27.8

peaches

GA

WDG

0.12

5

7 days

0.97

15

11

6

peaches

PA

WDG

0.12

5

7 days

0.94

22

9

7.7

Peaches Average

20

7

strawberries

NC

WDG

0.18

5

7 days

0.77

26

15

4.2

strawberries

CA

WDG

0.18

5

7 days

0.98

25

15

4.4

strawberries

OR

WDG

0.18

5

7 days

0.91

12

13

4.9

      Strawberry Average

21

14

peanuts

NC

EC

0.25

5

14 days

0.91

18

26

2.3

peanuts

GA

EC

0.25

5

14 days

0.77

17

61*

0.74

peanuts

TX

EC

0.25

5

14 days

0.91

18

24

2.5

  Peanuts Average

18

25*

grapes

CA

WDG

0.18

3

14 days

0.97

22

6

11.1

grapes

WA

WDG

0.18

3

14 days

0.94

25

6

11.8

grapes

PA

WDG

0.18

3

14 days

0.82

14

4

15.6

      Grapes WDG Average

20

5

grapes

CA

EC

0.18

3

14 days

0.95

14

9

7.4

grapes

WA

EC

0.18

3

14 days

0.9

22

9

7.5

grapes

PA

EC

0.18

3

14 days

0.79

12

5

13.9

grapes

CA

EC

0.15

6

10 days

0.9

6

6

12

grapes

NY

EC

0.15

6

10 days

0.92

28

6

11.2

grapes

WA

EC

0.15

6

10 days

0.9

24

4

17.3

      Grapes EC Average

18

7

EC Average

18

13

    WDG Average

20

9

WDG = water dispersible granule

EC = emulsifiable concentrate

* The results from the Georgia site reflect uncharacteristically high
rainfall during the monitoring period.  This is not representative of
typical conditions, therefore, the dissipation from this site was not
included in the average.

Table 20.  Summary of Estimated Postapplication MOEs for Foliar
Treatments

Crop	Application Rate

(lb ai/A) 1	DAT 2	DFR 3

(μg/cm2)	TC 4

(cm2/hr)	Activity 4	Short-/Int-

Term MOE 5

Canola & Flax 	0.10	0	0.20	100	Irrigating and scouting immature/low
foliage plants	13,000

1,500	Irrigating and scouting mature/high foliage plants	890

Oats	0.15	0	0.30	100	Irrigating and scouting immature/low foliage plants
8,900

1,500	Irrigating and scouting mature/high foliage plants	590

Herbs

0	0.34	500	Irrigation, scouting, thinning, weeding immature plants	1,600

1,500	Irrigating and scouting mature plants	530

2,500	Hand harvesting, pruning, and thinning mature plants	320

Tropical Fruit

0	0.34	100	Propping	8,000

1,000	Irrigation, scouting, weeding	800

1,500	Harvesting, pruning, training, tying	530

3,000	Thinning	270

1 Maximum application rate indicated on proposed labels (see Table 1).

2 DAT = Days after treatment needed to reach the LOC of 100; DAT 0 = the
day of treatment, after sprays have dried; assumed to be approximately
12 hours.

3 DFR (µg/cm2) = Application rate (lb ai/A) x CF (4.54E+8 ug/lb) x CF
(2.47E-8 A/cm2) x Initial Fraction of ai Retained on the Foliage (from
Table 19, used EC average [18%] for canola, flax and oats, and WDG
average [20%] for herbs and tropical fruits).

4 TC (cm2/hr) = transfer coefficients and associated activities from
ExpoSAC Policy Memo #003.1 “Agricultural Transfer Coefficients”,
8/17/2000.

5 MOE = MOE on the corresponding DAT.  MOE = NOAEL / Daily Dose.

   Daily Dose = [(DFR x  TC x 14% Dermal absorption  x  8-hr Exposure
Time)] / [(CF: 1000 µg/mg) x (60-kg Body Weight)]

   Short-/intermediate-term Dermal NOAEL = 5 mg/kg/day.  The LOC is 100.

10.0	Data Needs and Label Recommendations  TC \l1 "10.0	Data Needs and
Label Recommendations

10.1	Residue Chemistry Data Needs and Label Recommendations  TC \l2
"10.1	Residue Chemistry Data Needs and Label Recommendations

For Petition #6F7105

860.1500 Crop Field Trials

Oats:  No residue data are submitted for oat forage.  The petitioner did
not provide residue data or propose a tolerance for oat forage because
applications are made after the growth stages at which oat is foraged.
Based on the current proposed use patterns, the Agency will not require
residue data or a tolerance for oat forage.

860.1900 Field Accumulation in Rotational Crops

Label revisions are required to specify a 14-day plantback interval
restriction for all annual crops that are not registered.

860.1550 Proposed Tolerances

The petitioner should submit a revised Section F reflecting the
recommended tolerances and commodity definitions presented in Table 14.

The petitioner should submit a revised Section F to propose individual
tolerances of 0.45 ppm for all oilseeds in subgroups rapeseed,
sunflower, and cotton, as follows: 1) rapeseed (i.e., borage, crambe,
cuphea, echium, flax seed, gold of pleasure, hare’s ear mustard,
lesquerella, lunaria, meadowfoam, milkweed, mustard seed, oil radish,
poppy seed, rapeseed, sesame, and sweet rocket); 2) sunflower (i.e.,
Castor oil plant, Chinese tallowtree, Euphorbia, Evening primrose,
Jojoba, Niger seed, Rose hip, Safflower, Stokes aster, Sunflower,
Tallowwood, Tea oil plant, Vernonia ); and 3) cotton (only entry
presently in this subgroup).

Note: The existing tolerances on sunflower at 0.3 ppm and cotton,
undelinted seed at 0.3 ppm should be removed from 40 CFR §180.582.

860.1520 Processed Food and Feed

Oats:  No residue data for the oat processed commodities (flour and
groats/rolled oats) are submitted.  However, data from the wheat
processing studies (MRID #’s 45118620 and 45321101) can be translated
to adequately support the proposed use on oat.  Based on the wheat
studies, residues are not expected to concentrate in oat processed
commodities.

Barley:  No residue data for the barley processed commodities (bran and
pearled) are submitted.  However, data from the wheat processing studies
(MRID #’s 45118620 and 45321101) can be translated to adequately
support the proposed use on barley.  Based on the wheat studies,
residues are not expected to concentrate in barley processed
commodities.

For Petition #6E7165

860.1500 Crop Field Trials

The submitted residue data for avocado are inadequate to fulfill data
requirements because the field trials were conducted at exaggerated
rates (ca 2.6x).  Since the submitted data represent an overestimate of
the residues expected from the proposed use, HED considers that the
tolerance for avocado may need to be reduced.  Also, since the proposed
use is for late season foliar application, includes a 0-day preharvest
interval, and these data are being translated to support a wide number
of tropical/subtropical fruits, HED requests that the petitioner provide
additional, bridging field trial data (i.e., two to three field trials
at the proposed label rate of 2 applications, total 0.3 lb ai/season) as
a condition of registration.

860.1900 Field Accumulation in Rotational Crops

Label revisions are required to specify a 14-day plantback interval
restriction for all annual crops that are not registered.

860.1550 Proposed Tolerances

The petitioner should submit a revised Section F to correct the
tolerance residue definition (parent + metabolite) and to make it
consistent with the definition listed in 40 CFR §180.582 (a)(1).  The
revised Section F should also incorporate the recommended tolerances and
commodity definitions presented in Table 14.

For Petition #7E7245

860.1500 Crop Field Trials

Barley:  No residue data were submitted for barley forage, and these
data are normally required to support the amended use pattern.
However, the petitioner did not provide residue data or propose a
tolerance for barley hay because applications are made after the growth
stages at which barley hay is harvested.  Based on the current proposed
use patterns, the Agency will not require residue data or a tolerance
for barley hay.

860.1520 Processed Food and Feed

Barley:  Residue data for the barley processed commodities (pearled
barley and bran) are normally required.  However, data from the wheat
processing studies (MRID #’s 45118620 and 45321101) can be translated
to adequately support the proposed use on barley.  Based on the wheat
studies, residues are not expected to concentrate in barley processed
commodities.

860.1900 Field Accumulation in Rotational Crops

Label revisions are required to specify a 14-day plantback interval
restriction for all annual crops that are not registered.

860.1550 Proposed Tolerances

The petitioner should submit a revised Section F reflecting the
recommended tolerances and commodity definitions presented in Table 14.

10.2	Occupational Label Recommendations  TC \l2 "10.2	Occupational Label
Recommendations

The proposed Headline® Fungicide label requires chemical resistant
gloves; however, a respirator is not indicated and is needed for the
handler scenario of mixing/loading liquids for aerial application or
chemigation.

The proposed BAS 500 ST label is a supplemental label only, and does not
provide information regarding personal protective equipment (PPE).  Such
PPE information should be added to the label.  Gloves are needed for
several seed treatment scenarios, and a respirator is needed for the
multiple activity scenario.

11.0	International Residue Limit Status  TC \l1 "11.0	International
Residue Limit Status

The Codex Alimentarius Commission, Mexico and Canada have not
established any maximum residue limits (MRLs) for residues of
pyraclostrobin in or on raw agricultural commodities, although a variety
of MRLs are pending in Canada.  Therefore, there are no questions of
compatibility of U.S. tolerances with International MRLs at the present
time.

INTERNATIONAL RESIDUE LIMIT STATUS

Chemical Name:  methyl
[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]methoxy
carbamate	Common Name:

Pyraclostrobin	(   Proposed tolerances

(  Reevaluated tolerance

(  Other	Date: 12/20/07

Codex Status (Maximum Residue Limits)	U. S. Tolerances

No Codex proposal step 6 or above

No Codex proposal step 6 or above for the crops requested
Petition Numbers:  6E7105, 6E7165, and 7E7245

DP#s:  334535, 336189, and 343754

Other Identifier:

Residue definition (step 8/CXL):  pyraclostrobin (fat soluble)
Reviewers/Branch: B. Cropp-Kohlligan, G. Otakie, J. Stokes / RRB4

	Residue definition in PP#6E7105, PP#6E7165,and PP#7E7245:  Combined
residues of pyraclostrobin and BF 500-3, expressed as pyraclostrobin.

Crop (s)	MRL (mg/kg)	Crop(s)	Recommended Tolerance (ppm)

Oats	0.5	PP#6E7105

Papaya	0.05	Oats grain	1.2

Barley	0.5	Oats, hay 	18

Oats, straw	15

Canola, seed	0.45

Flax, seed 	0.45

Borage	0.45

Crambe	0.45

Cuphea	0.45

Echium	0.45

Flax seed	0.45

Gold of pleasure	0.45

Hare’s ear mustard	0.45

Lesquerella	0.45

Lunaria	0.45

Meadowfoam	0.45

Milkweed	0.45

Mustard seed	0.45

Oil radish	0.45

Poppy seed	0.45

Rapeseed	0.45

Sesame	0.45

Sweet rocket	0.45

Castor oil plant	0.45

Chinese tallowtree	0.45

Euphorbia	0.45

Evening primrose	0.45

Jojoba	0.45

Niger seed	0.45

Rose hip	0.45

Safflower	0.45

Stokes aster	0.45

Sunflower	0.45

Tallowwood	0.45

Tea oil plant	0.45

Vernonia	0.45

Cotton	0.45

PP#6E7165

Avocado	0.6

Sapote, black	0.6

Canistel	0.6

Sapote, mamey	0.6

Mango	0.6

Papaya	0.6

Sapodilla	0.6

Star Apple	0.6

PP#7E7245

Barley, grain	1.4

Barley, straw	6.0

Limits for Canada	Limits for Mexico

(No Limits

(No Limits for the crops requested	(No Limits

(No Limits for the crops requested

Residue definition:	Residue definition:

Crop(s)	MRL (mg/kg)	Crop(s)	MRL (ppm)

	Notes/Special Instructions:

12.0	Appendix: Toxicity Profile  TC \l1 "12.0	Appendix: Toxicity Profile

12.1	Appendix 1.: Pyraclostrobin Toxicology Requirements and Available
Studies for Food Uses  TC \l2 "12.1	Appendix 1.: Pyraclostrobin
Toxicology Requirements and Available Studies for Food Uses

Appendix 1: Pyraclostrobin Toxicology Requirements and Available Studies
for Food Uses.

  SEQ CHAPTER \h \r 1 Test

	Technical

	Required	Satisfied

870.1100	Acute Oral Toxicity

870.1200	Acute Dermal Toxicity

870.1300	Acute Inhalation Toxicity

870.2400	Primary Eye Irritation

870.2500	Primary Dermal Irritation

870.2600	Dermal Sensitization		yes

yes

yes

yes

yes

yes	yes

yes

yes

yes

yes

yes

870.3100	Oral Subchronic (rodent)

870.3150	Oral Subchronic (dog)

870.3200	28-Day Dermal

870.3465	28-Day Inhalation		yes

yes

yes

yes	yes

yes

yes

yes

870.3700a	Developmental Toxicity (rat)

870.3700b	Developmental Toxicity (rabbit)

870.3800	Reproduction		yes

yes

yes	yes

yes

yes

870.4100a	Chronic Toxicity (rat)

870.4100b	Chronic Toxicity (dog)

870.4200a	Oncogenicity (rat)

870.4200b	Oncogenicity (mouse)		yes

yes

yes

yes	yes

yes

yes

yes

870.5100	Mutagenicity—Gene Mutation - bacterial

870.5300	Mutagenicity—Gene Mutation - mammalian

870.5375	Mutagenicity—Structural Chromosomal Aberrations

870.5395	Mutagenicity—Microneucleus - mammalian

870.5550	Mutagenicity—Unscheduled DNA - mammalian 		yes

yes

yes

yes

yes	yes

yes

yes

yes

yes

870.6100a	Acute Delayed Neurotox. (hen)

870.6100b	90-Day Neurotoxicity (hen)

870.6200a	Acute Neurotox. Screening Battery (rat)

870.6200b	90 Day Neuro. Screening Battery (rat)

870.6300	Develop. Neuro		no

no

yes

yes

no

	-

-

yes

yes

-

870.7485	General Metabolism

870.7600	Dermal Penetration		yes

yes	yes

yes

12.2	Appendix 2.: Acute Toxicity Data on Pyraclostrobin Technical  TC
\l2 "12.2	Appendix 2.: Acute Toxicity Data on Pyraclostrobin Technical

  SEQ CHAPTER \h \r 1 Appendix 2. Acute Toxicity Profile:

  SEQ CHAPTER \h \r 1 Table 1. Acute Toxicity Data on Pyraclostrobin
Technical

Study/ Species	MRID	Results	Toxicity  Category

870.1100 Acute Oral, Rats	45118302	LD50 = > 5000 mg/kg	IV

870.1200 Acute Dermal, Rabbits	45118305	LD50 = >2000mg/kg	III

870.1300 Acute Inhalation, Rats	45118308	0.31 mg/L < LC50 < 1.07 mg/L	II

870.2400 Primary Eye Irritation, Rabbits	45118311	Moderate eye
irritation; MAS 4.6/110	III

870.2500 Primary Skin Irritation, Rabbits	45118314	Moderate skin
irritation; MAS 2.2/8.0	III

870.2600 Dermal Sensitization, Guinea pig	45118317	Not a skin sensitizer
N/A

12.3	Appendix 3.: Subchronic, Chronic and Other Toxicity Profile  TC
\l2 "12.3	Appendix 3.: Subchronic, Chronic and Other Toxicity Profile

  SEQ CHAPTER \h \r 1 Appendix 3. Subchronic, Chronic and Other Toxicity
Profile

Guideline No./Study Type	MRID No. (year)/ Classification/Doses	Results

870.3100

90-Day oral toxicity (rat)	45118321 (1999)

Acceptable/guideline

0, 50, 150, 500, 1000, 1500 ppm

M: 0, 3.5, 10.7, 34.7, 68.8, 105.8 mg/kg/day;

F: 0, 4.2 12.6, 40.8, 79.7,118.9  mg/kg/day	NOAEL = 10.7 mg/kg/day

EL = 34.7 mg/kg/day based on ↓body weight/ weight gain in males,
↓food intake (both sexes), ↑ relative liver wt and spleen wt in
females and histopathology of duodenum and liver in males, and spleen in
both sexes.

870.3100

90-Day oral toxicity

(mouse)	45118320 (1999)

Acceptable/guideline

0, 50, 150, 500, 1000, 1500 ppm

M: 0, 9.2, 30.4, 119.4, 274.4, 475.5 mg/kg/day

F:0, 12.9, 40.4, 162.0, 374.1, 634.8 mg/kg/day	NOAEL = 9.2 mg/kg/day

LOAEL =  30.4 mg/kg/day based on ↓body weight/ weight gain in males,
changes in clinical chemistry in both sexes (increased urea and
decreased triglycerides), and increased incidences in females of lymph
node apoptosis, thymus atrophy, and ulcer/erosion in the glandular
stomach.

870.3150

90-Day oral toxicity (dog)	45118323 (1999)

Acceptable/guideline

0, 100, 200, 450 ppm

M: 0, 2.8, 5.8, 12.9 mg/kg/day

F: 0, 3.0, 6.2, 13.6 mg/kg/day	NOAEL = 5.8 mg/kg/day

LOAEL = 12.9 mg/kg/day based on ↑diarrhea, clinical chem. changes, and
increased incidence of thickening/ mucosal hypertrophy of the duodenum
in both sexes; body weight loss, and ↓food intake/efficiency in
females.

870.3050

28-Day oral toxicity (rat)

	MRID 45118322 (1999)

Acceptable/guideline

0, 20, 100, 500, 1500 ppm

M: 0, 1.8, 9.0, 42.3, 120.2 mg/kg/day

F: 0, 2.0 9.6, 46.6, 126.3  mg/kg/day	NOAEL =  9.0 mg/kg/day

LOAEL = 42.3 mg/kg/day based on changes in hematology parameters,
increased absolute and relative spleen weight, histopathology in spleen
and liver, in addition to increased duodenal mucosal hyperplasia in both
sexes.

870.3200

28-Day dermal toxicity (rat)	45118324 (1999) Unacceptable/guideline (a
higher dose could be tolerated and the limit dose is 1000 mg/kg/day)

0, 40, 100, 250 mg/kg for 5 days/wk	Dermal NOAEL = 40 mg/kg/day

Dermal LOAEL = 100 mg/kg/day based on scale formation, hyperkeratosis,
and epidermal thickening.

Systemic NOAEL = 250 mg/kg/day

Systemic LOAEL > 250 mg/kg/day

The HIARC (TXR 0051553) determined that a repeat study at a higher dose
is not needed since an oral end-point (developmental toxicity NOAEL of
5.0 mg/kg/day) with a 14% dermal absorption rate yields a dermal
equivalent dose of 36 mg/kg/day (5 ÷ 0.14) which is well below the
apparent systemic toxicity NOAEL of 250 mg/kg/day in the dermal study.

870.3465

28-Day inhalation toxicity (rat)	46638801 (2005)

Acceptable/guideline

0.001, 0.030, or 0.300 mg/L for 6 hours per day, 5 days/week (20
exposure days) – Test substance was dissolved in acetone and
administered as an aerosol	Inhalation NOAEL = 0.001 mg/L (oral
equivalent dose = 0.23 mg/kg/day)

Inhalation LOAEL = 0.030 mg/L (oral equivalent dose = 6.9 mg/kg/day)
based on findings of hyperplasia in the duodenum, alveolar histiocytosis
in the lungs, and olfactory atrophy/necrosis in the nasal tissues.

870.3700a

Prenatal developmental (rat)	45118325 (1999)

Acceptable/guideline

0, 10, 25, 50 mg/kg/day	Maternal NOAEL = 10 mg/kg/day

LOAEL = 25 mg/kg/day based on ↓body wt/ wt gain and ↓food
intake/efficiency.

Developmental NOAEL = 25 mg/kg/day

LOAEL = 50 mg/kg/day based on ↑ incidences of dilated renal pelvis and
cervical ribs with no cartilage.

870.3700b

Prenatal developmental (rabbit)	45118326 and 45437001 (1999)
Acceptable/guideline

0, 1, 3, 5, 10, 20 mg/kg/day	Maternal NOAEL = 5 mg/kg/day

LOAEL = 10 mg/kg/day based on ↓ body wt gain and ↓food
intake/efficiency.

Developmental NOAEL = 5 mg/kg/day

LOAEL =10 mg/kg/day based on ↑ resorption/post-implantation loss.

870.3800

Reproduction and fertility effects

(rat)	Two Generation: MRID 45118327 (1999) Acceptable/guideline when
combined with the one generation preliminary study (below)

0, 25, 75, 300 ppm

F0 M/F: 0, 2.5/2.6, 7.4/7.8, 29.0/30.4 mg/kg/day

F1 M/F: 0, 2.8/3.0, 8.6/9.0, 35.0/36.0 mg/kg/day

One Generation: MRID 45596210 (2002)

0, 200, 400, 600 ppm

F0 M/F: 0, 20.5/21.3, 39.9/42.5, 59.1/60.4 mg/kg/day	Parental/Systemic
NOAEL = 29 mg/kg/day

LOAEL > 29 mg/kg/day based on no effects.

Reproductive NOAEL = 29 mg/kg/day

LOAEL > 29 mg/kg/day based on no effects.

Offspring NOAEL =  29 mg/kg/day

LOAEL > 29  mg/kg/day based on no effects.

Offspring NOAEL < 20.5 mg/kg/day

Offspring LOAEL = 20.5 mg/kg/day based on decreased pup body weight and
body weight gain on and after post-natal day 7.

870.4100a

Chronic toxicity

(rat)	45118329 (1999) Unacceptable/guideline

0, 25, 75, 200 ppm

M: 0, 1.1, 3.4, 9.0 mg/kg/day

F: 0, 1.5, 4.6, 12.3 mg/kg/day	NOAEL =  9.0 mg/kg/day

LOAEL > 9.0 mg/kg/day.

870.4100b

Chronic toxicity (dog)	45118328 (1999)

Acceptable/guideline

0, 100, 200, 400 ppm

M: 0, 2.7, 5.4, 10.8 mg/kg/day

F: 0, 2.7, 5.4, 11.2 mg/kg/day	NOAEL = 5.4 mg/kg/day

LOAEL = 10.8 mg/kg/day based on ↑ diarrhea and clinical chemistry
changes in both sexes (decreased cholesterol, protein, albumin, and
globulin), and ↓ body weight gain and ↓food intake/efficiency in
females.

870.4200

Carcinogenicity

(rat)	45118331 (1999)

Acceptable/guideline

0, 25, 75, 200 ppm

M: 0, 1.2, 3.4, 9.2 mg/kg/day

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kg/day

LOAEL =  9.2 mg/kg/day based on ↓ body weight and body weight gain,
and kidney atrophy/tubular casts in both sexes; hepatic necrosis and
gross/ microscopic ulcerations/lesions in the glandular and
fore-stomachs in males.

No evidence of carcinogenicity

870.4300

Carcinogenicity

(mouse)	45118330 (1999) Unacceptable/guideline

M: 0, 10, 30, 120 ppm

0, 1.4, 4.1, 17.2 mg/kg/day

F: 0, 10, 30, 120, 180 ppm

0, 1.6, 4.8, 20.5, 32.8 mg/kg/day	NOAEL =  M: 4.1 mg/kg/day

	     F:  32.8 mg/kg/day

LOAEL =  M: 17.1 mg/kg/day based on decrease in body weight gain (20%)
at 13 weeks which was supported by the results of a 90-day study.

	    F >32.8 mg/kg/day

Inadequate dosing in females based on CARC Report dated 10/22/03 (TXR #
0051445)

No evidence of carcinogenicity

Gene Mutation

870.870.5100

Bacterial reverse mutation assay	45118332 (1997)

Acceptable/guideline	Negative  ± S9 up to 5,000 μg/plate by standard
plate and tube preincubation. No cytotoxicity at any dose but there was
precipitation at ≥2,500 μg/plate.

Gene Mutation

870.5300

Mammalian cell culture	45118335 (1998)

Acceptable/guideline	Negative  ± S9 up to cytotoxic and precipitating
concentration of 20 μg/mL

Cytogenetics (in vitro)

870.5375 Chromosomal aberrations	45118333 (1999)

Acceptable/guideline	Negative ± S9 for clastogenic/aneugenic activity
up to 25 μg/mL.  Precipitation and cytotoxicity (reduced cell
attachment and poor quality of metaphases) were seen at concentrations
≥50  μg/mL.

Cytogenetics

870.5395

Micronucleus test in mouse	45118334 (1998)

Acceptable/guideline	Negative for clastogenic/aneugenic activity up to
the highest dose tested (300 mg/kg).  In a preliminary study, doses
≥400 mg/kg caused death.

Unscheduled DNA synthesis

870.5550

Rat hepatocyte culture	45118336 (1998)

Acceptable/guideline	Negative up to a cytotoxic concentration of 1.0
µg/mL.

870.6200a

Acute neurotoxicity screening (rat)	45118337(1999)

Acceptable/guideline

0, 100, 300, 1000 mg/kg	Neurotoxicity NOAEL = 1000 mg/kg

M/F LOAEL >1000 mg/kg

Systemic M/F NOAEL = 300/〱〰洠⽧杫

M/F LOAEL 1000/ >1000 mg/kg based on ↓body weight gain in males.

870.6200b

Subchronic neurotoxicity screening (rat)	45118401 (1999)

Acceptable/guideline

0, 50, 250, 750 (M)/1500 (F) ppm

M: 0, 3.5, 16.9, 49.9 mg/kg/day

F: 0, 4.0, 20.4, 111.9 mg/kg/day	Neurotoxicity M/F NOAEL =  49.9/111.9
mg/kg/day

M/F LOAEL  >49.9/111.9 mg/kg/day.

Systemic M/F NOAEL =  16.9/20.4 mg/kg/day

M/F LOAEL =  49.9/111.9 mg/kg/day based on ↓ body weight gain, and ↓
food intake/efficiency.

870.7485

s

(rat)	 45118403 (1998)

 45118404 (1999)

Acceptable/guideline	Nearly 35% of an oral dose of pyraclostrobin is
absorbed with urinary and fecal excretions accounting for about 15% and
85%, respectively, and bile elimination accounted for about 30%. Two
peak plasma concentrations were reached at 0.5-1 and 8 hours with lower
plasma concentrations in males than females (by 16-38%) during the early
peak phase.  Elimination was biphasic at a low dose with plasma half
lives of nearly 10/35 hours and monophasic at a high dose with a
half-life of nearly 20 hours.  Tissue distribution was fast, peaking at
0.5 hours, and was slightly higher among females.  Some of the highest
concentrations were found in the liver, thyroid, kidney, lung, adrenal
glands, and pancreas but all levels dropped by more than 20-fold within
72 hours. About 33 metabolites were identified in urine, feces, and bile
with no sex- or dose-related differences but the position of the label
seemed to alter the profile, particularly in the urine.  Desmethoxy
pyraclostrobin (500M07) is one of the major metabolites in rat and is
also found in large amounts in plants (BF 500-3) and livestock (500M07).
 The rat metabolic pathway included phase-I reactions such as
N-demethoxylation, various hydroxylations, and cleavage of the ether
bond with subsequent oxidation; these reactions were followed by phase
II glucuronidation and sulfation.

870.7600

Dermal penetration

(rat)	45118402 (1999) Unacceptable/guideline (most of the test material
was retained on the dressing and was unavailable for absorption;
therefore, actual dose cannot be determined. 	The HIARC calculated and
recommended a dermal penetration rate of 14% (report dated 2/10/03; TXR
# 0051553)

Page   PAGE  1  of   NUMPAGES  68


[Federal Register Volume 80, Number 90 (Monday, May 11, 2015)]
[Notices]
[Page 26966]
[FR Doc No: 2015-11365]

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SECURITIES AND EXCHANGE COMMISSION

Sunshine Act Meeting

    Notice is hereby given, pursuant to the provisions of the
Government in the Sunshine Act, Public Law 94-409, that the Securities
and Exchange Commission Equity Market Structure Advisory Committee will
hold a public meeting on Wednesday, May 13, 2015, in the Multipurpose
Room, LL-006 at the Commission's headquarters, 100 F Street NE.,
Washington, DC.
    The meeting will begin at 9:30 a.m. (EDT) and will be open to the
public. Seating will be on a first-come, first-served basis. Doors will
be open at 9:00 a.m. Visitors will be subject to security checks. The
meeting will be webcast on the Commission's Web site at www.sec.gov.
    On April 23, 2015, the Commission published notice of the Committee
meeting (Release No. 34-74793), indicating that the meeting is open to
the public and inviting the public to submit written comments to the
Committee. This Sunshine Act notice is being issued because a majority
of the Commission may attend the meeting.
    The agenda for the meeting will focus on Rule 611 of SEC Regulation
NMS.
    For further information, please contact the Office of the Secretary
at<PHONE_NUMBER>.

    Dated: May 6, 2015.
Brent J. Fields,
Secretary.
[FR Doc. 2015-11365 Filed 5-7-15; 11:15 am]
 BILLING CODE 8011-01-P


eived electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received 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electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC App. H 8 of RM# 34762 received electronically from MBC Impingement & entrainment losses data for Huntington Beach Power Station, Southern California. Amy Gage, 6/ 3/ 2003


[Federal Register Volume 82, Number 58 (Tuesday, March 28, 2017)]
[Notices]
[Pages 15356-15357]
[FR Doc No: 2017-06035]

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DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. EL16-6-004]

PJM Interconnection, L.L.C.; Notice of Filing

    Take notice that on March 2, 2017, PJM Interconnection, L.L.C.
submitted tariff filing per: Further Compliance Filing to be effective
February 1, 2017, pursuant to the Federal Energy Regulatory
Commission's (Commission) Order issued on January 31, 2017 Order.\1\
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    \1\ PJM Interconnection, LLC, et al., 158 FERC 61,093 (2017).
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    Any person desiring to intervene or to protest this filing must
file in accordance with Rules 211 and 214 of the Commission's Rules of
Practice and Procedure (18 CFR 385.211, 385.214). Protests will be
considered by the Commission in determining the appropriate action to
be taken, but will not serve to make protestants parties to the
proceeding. Any person wishing to become a party must file a notice of
intervention or motion to intervene, as appropriate. Such notices,
motions, or protests must be filed on or before the comment date. On or
before the comment date, it is not necessary to serve motions to
intervene or protests on persons other than the Applicant.
    The Commission encourages electronic submission of protests and
interventions in lieu of paper using the ``eFiling'' link at http://www.ferc.gov. Persons unable to file electronically should submit an
original and 5 copies of the protest or intervention to the Federal
Energy Regulatory Commission, 888 First Street NE., Washington, DC
20426.
    This filing is accessible on-line at http://www.ferc.gov, using the
``eLibrary'' link and is available for review in the Commission's
Public Reference Room in Washington, DC. There is an ``eSubscription''
link on the Web site that enables subscribers to receive email
notification when a document is added to a subscribed docket(s). For
assistance with any FERC Online service, please email
<EMAIL_ADDRESS>or call<PHONE_NUMBER> (toll free). For
TTY, call<PHONE_NUMBER>.

    Comment Date: 5:00 p.m. Eastern Time on April 4, 2017.

    Dated: March 21, 2017.
Kimberly D. Bose,
Secretary.
[FR Doc. 2017-06035 Filed 3-27-17; 8:45 am]
BILLING CODE 6717-01-P


[Federal Register: March 15, 2006 (Volume 71, Number 50)]
[Notices]
[Page 13382-13384]
[DOCID:fr15mr06-104]

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DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

Meetings; Sunshine Act

March 9, 2006.
    The following notice of meeting is published pursuant to section
3(a) of the government in the Sunshine Act (Pub. L. No. 94-409), 5
U.S.C 552b:

Agency Holding Meeting: Federal Energy Regulatory Commission.

Date and Time: March 16, 2006, 10 a.m.

Place: Room 2C, 888 First Street NE., Washington DC 20426.

Status: Open.

Matters to be Considered: Agenda.
    *Note--Items listed on the agenda may be deleted without further
notice.

Contact person for more information: Magalie R. Salas, Secretary,
Telephone<PHONE_NUMBER>. For a recorded listing item stricken from or
added to the meeting, call<PHONE_NUMBER>.
    This is a list of matters to be considered by the Commission. It
does not include a listing of all papers relevant to the items on the
agenda; however, all public documents may be examined in the Public
Reference Room.

                     903rd--Meeting--Regular Meeting
                        [March 16, 2006, 10 a.m.]
------------------------------------------------------------------------
     Item No.              Docket No.                   Company
------------------------------------------------------------------------
                          Administrative Agenda
------------------------------------------------------------------------
A-1..............  AD02-1-000................  Agency Administrative
                                                Matters.
A-2..............  AD02-7-000................  Customer Matters,
                                                Reliability, Security
                                                and Market Operations.
A-3..............  AD06-3-000................  Energy Market Update.
------------------------------------------------------------------------
                                Electric
------------------------------------------------------------------------
E-1..............  OMITTED...................
E-2..............  OMITTED...................
E-3..............  EC03-131-003, EC03-131-004  Oklahoma Gas and Electric
                                                Company and McClain LLC
E-4..............  ER96-719-006, EL05-59-000.  MidAmerican Energy
                                                Company.
                   ER96-719-008, ER99-2156-    Cordova Energy Company
                    006.                        LLC.
E-5..............  ER06-451-000..............  Southwest Power Pool,
                                                Inc.
E-6..............  ER06-356-000, ER06-356-001  Midwest Independent
                                                Transmission System
                                                Operator, Inc.
E-7..............  ER06-493-000..............  Midwest Independent
                                                Transmission System
                                                Operator, Inc.
E-8..............  ER06-487-000..............  PJM Interconnection,
                                                L.L.C. and the PJM
                                                Transmission Owners.
                   ER06-488-000..............  PJM Interconnection,
                                                L.L.C., and Virginia
                                                Electric and Power
                                                Company (PJM South).
                   ER06-489-000..............  PJM Interconnection,
                                                L.L.C., and Monongahela
                                                Power Company, The
                                                Potomac Edison Company
                                                and West Penn Power
                                                Company, all doing
                                                business as Allegheny
                                                Power, American Electric
                                                Power Service
                                                Corporation on behalf of
                                                its Operating Companies:
                                                Appalachian Power
                                                Company, Columbus
                                                Southern Power Company,
                                                Indiana Michigan Power
                                                Company, Kentucky Power
                                                Company, Kingsport Power
                                                Company, Ohio Power
                                                Company, and Wheeling
                                                Power Company;
                                                Commonwealth Edison
                                                Company, Commonwealth
                                                Edison Company of
                                                Indiana, and Dayton
                                                Power and Light Company
                                                (PJM West).
                   ER06-490-000..............  Public Service Electric
                                                and Gas Company, PECO
                                                Energy Company, PPL
                                                Electric Utilities
                                                Corporation, Baltimore
                                                Gas and Electric
                                                Company, Jersey Central
                                                Power & Light Company,
                                                Metropolitan Edison
                                                Company, Pennsylvania
                                                Electric Company,
                                                Potomac Electric Power
                                                Company, Atlantic City
                                                Electric Company,
                                                Delmarva Power & Light
                                                Company, UGI Utilities,
                                                Inc., Allegheny Electric
                                                Cooperative, Inc., CED
                                                Rock Springs, LLC, Old
                                                Dominion Electric
                                                Cooperative, Rockland
                                                Electric Company, and
                                                Duquesne Light Company.
E-9..............  ER06-506-000, ER06-506-001  New York Independent
                                                System Operator, Inc.
E-10.............  ER06-522-000..............  Midwest Independent
                                                Transmission System
                                                Operator, Inc.
E-11.............  ER97-4345-017.............  Oklahoma Gas and Electric
                                                Company.
                   ER98-511-005, EL05-107-000  OGE Energy Resources,
                                                Inc.
E-12.............  ER01-2230-001,ER01-2230-00  New York Independent
                    2.                          System Operator, Inc.
E-13.............  OMITTED...................
E-14.............  OMITTED...................
E-15.............  ER02-2263-003, ER02-2263-   Southern California
                    004, ER02-2263-005.         Edison Company.
E-16.............  ER03-1079-006.............  Aquila, Inc.
                   ER02-47-006...............  Aquila Long Term, Inc.
                   ER95-216-026..............  Aquila Merchant Services,
                                                Inc.
                   ER03-725-006..............  Aquila Piatt County
                                                L.L.C.
                   ER02-309-006..............  MEP Clarksdale Power,
                                                LLC.
                   ER02-1016-004.............  MEP Flora Power, LLC.
                   EL05-83-000, EL05-83-001..  Aquila, Inc., Aquila Long
                                                Term, Inc., Aquila
                                                Merchant Services, Inc.,
                                                Aquila Piatt County
                                                L.L.C., MEP Clarksdale
                                                Power, LLC, and MEP
                                                Flora Power, LLC.
E-17.............  OMITTED...................
E-18.............  OMITTED...................
E-19.............  EL04-57-002...............  FPL Energy Marcus Hook,
                                                L.P. v. PJM
                                                Interconnection, L.L.C.
E-20.............  OMITTED...................
E-21.............  ER05-130-001, ER05-130-     Pacific Gas and Electric
                    003, ER05-150-00.           Company.
E-22.............  OMITTED...................
E-23.............  ER06-207-001, ER06-208-     Xcel Energy Services Inc.
                    001, ER06-209-001, ER06-
                    210-001.
E-24.............  OMITTED...................
E-25.............  OMITTED...................
E-26.............  ER04-938-003, ER04-938-004  California Independent
                                                System Operator
                                                Corporation.
E-27.............  OMITTED...................
E-28.............  ER05-611-003..............  Bridgeport Energy, LLC.
E-29.............  EL05-49-001...............  Exelon Corporation v. PPL
                                                Electric Utilities
                                                Corporation and PJM
                                                Interconnection, LLC.

E-30.............  ER00-2268-003, ER00-2268-   Pinnacle West Capital
                    005, ER00-2268-006, ER00-   Corporation.
                    2268-007, ER00-2268-008,
                    ER00-2268-010, ER00-2268-
                    012, ER00-2268-013, ER00-
                    2268-015, EL05-10-002.
                   ER99-4124-001, ER99-4124-   Arizona Public Service
                    003, ER99-4124-004, ER99-   Company.
                    4124-005, ER99-4124-006,
                    ER99-4124-008, ER99-4124-
                    010, ER99-4124-011, ER99-
                    4124-013, EL05-11-002,
                    EL05-11-004.
                   ER00-3312-002, ER00-3312-   Pinnacle West Energy
                    004, ER00-3312-005, ER00-   Corporation.
                    3312-006, ER00-3312-007,
                    ER00-3312-009, ER00-3312-
                    011, ER00-3312-012, ER00-
                    3312-014, EL05-12-002,
                    EL05-12-004.
                   ER99-4122-004, ER99-4122-   APS Energy Services
                    006, ER99-4122-007, ER99-   Company, Inc.
                    4122-008, ER99-4122-009,
                    ER99-4122-011, ER99-4122-
                    013, ER99-4122-014, ER99-
                    4122-016, EL05-13-002,
                    EL05-13-004.
                   ER03-352-003..............  Gen West LLC.
E-31.............  ER06-517-000, ER06-524-000  California Independent
                                                System Operator
                                                Corporation.
E-32.............  ER06-532-000..............  Midwest Independent
                                                Transmission System
                                                Operator, Inc., and
                                                First Energy Services
                                                Company.
E-33.............  OMITTED...................
------------------------------------------------------------------------
                              Miscellaneous
------------------------------------------------------------------------
M-1..............  RM05-33-001...............  Revision of Rules of
                                                Practice and Procedure
                                                Regarding Issue
                                                Identification.
------------------------------------------------------------------------
                                   Gas
------------------------------------------------------------------------
G-1..............  RM05-22-0000..............  Five-Year Review of Oil
                                                Pipeline Pricing Index.
G-2..............  RP06-177-000..............  Iroquois Gas Transmission
                                                System, L.P.
G-3..............  RP05-668-002, RP05-668-001  Southern Star Central Gas
                                                Pipeline, Inc.
G-4..............  OR06-3-000................  Enbridge Energy, Limited
                                                Partnership.
G-5..............  RP05-422-000..............  El Paso Natural Gas
                                                Company.
G-6..............  OMITTED...................
------------------------------------------------------------------------
                         Energy Projects--Hydro
------------------------------------------------------------------------
H-1..............  P-2659-018................  PacifiCorp.
H-2..............  P-2738-061................  New York State Electric &
                                                Gas Corporation.
H-3..............  P-2056-038................  Northern States Power
                                                Company.
------------------------------------------------------------------------
                      Energy Projects--Certificates
------------------------------------------------------------------------
C-1..............  CP06-10-000...............  Dominion Transmission,
                                                Inc.
------------------------------------------------------------------------

Magalie R. Salas.
Secretary.
    A free Webcast of this event is available through http://www.ferc.gov.
 Anyone with Internet access who desires to view this

event can do so by navigating to http://www.ferc.gov's Calendar of

Events and locating this event in the Calendar. The event will contain
a link to its Webcast. The Capitol Connection provides technical
support for the free Webcasts. It also offers access to this event via
television in the DC area and via phone bridge for a fee. If you have
any questions, visit http://www.CapitolConnection.org or contact

Danelle Perkowski or David Reininger at<PHONE_NUMBER>.
    Immediately following the conclusion of the Commission Meeting, a
press briefing will be held in Hearing Room 2. Members of the public
may view this briefing in the Commission Meeting overflow room. This
statement is intended to notify the public that the press briefings
that follow Commission meetings may now be viewed remotely at
Commission headquarters, but will not be telecast through the Capitol
Connection service.
[FR Doc. 06-2586 Filed 3-13-06; 3:45 pm]

BILLING CODE 6717-01-P


[Federal Register Volume 84, Number 96 (Friday, May 17, 2019)]
[Notices]
[Pages 22489-22490]
[FR Doc No: 2019-10240]

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DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. ER19-1820-000]

Stony Knoll Solar, LLC; Supplemental Notice That Initial Market-
Based Rate Filing Includes Request for Blanket Section 204
Authorization

    This is a supplemental notice in the above-referenced proceeding of
Stony

Knoll Solar, LLC's application for market-based rate authority, with an
accompanying rate tariff, noting that such application includes a
request for blanket authorization, under 18 CFR part 34, of future
issuances of securities and assumptions of liability.
    Any person desiring to intervene or to protest should file with the
Federal Energy Regulatory Commission, 888 First Street NE, Washington,
DC 20426, in accordance with Rules 211 and 214 of the Commission's
Rules of Practice and Procedure (18 CFR 385.211 and 385.214). Anyone
filing a motion to intervene or protest must serve a copy of that
document on the Applicant.
    Notice is hereby given that the deadline for filing protests with
regard to the applicant's request for blanket authorization, under 18
CFR part 34, of future issuances of securities and assumptions of
liability, is June 3, 2019.
    The Commission encourages electronic submission of protests and
interventions in lieu of paper, using the FERC Online links at http://www.ferc.gov. To facilitate electronic service, persons with internet
access who will eFile a document and/or be listed as a contact for an
intervenor must create and validate an eRegistration account using the
eRegistration link. Select the eFiling link to log on and submit the
intervention or protests.
    Persons unable to file electronically should submit an original and
5 copies of the intervention or protest to the Federal Energy
Regulatory Commission, 888 First Street NE, Washington, DC 20426.
    The filings in the above-referenced proceeding are accessible in
the Commission's eLibrary system by clicking on the appropriate link in
the above list. They are also available for electronic review in the
Commission's Public Reference Room in Washington, DC. There is an
eSubscription link on the website that enables subscribers to receive
email notification when a document is added to a subscribed docket(s).
For assistance with any FERC Online service, please email
<EMAIL_ADDRESS>or call<PHONE_NUMBER> (toll free). For
TTY, call<PHONE_NUMBER>.

    Dated: May 13, 2019.
Nathaniel J. Davis, Sr.,
Deputy Secretary.
[FR Doc. 2019-10240 Filed 5-16-19; 8:45 am]
 BILLING CODE 6717-01-P


[Federal Register Volume 86, Number 79 (Tuesday, April 27, 2021)]
[Notices]
[Page 22196]
[FR Doc No: 2021-08746]

=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket Nos. AD21-6-000; AD20-6-000]

RTO/ISO Credit Principles and Practices; Credit Reforms in
Organized Wholesale Electric; Notice Inviting Post-Technical Conference
Comments

    On February 25 and 26, 2021, Federal Energy Regulatory Commission
(Commission) staff convened a technical conference to discuss
principles and best practices for credit risk management in organized
wholesale electric markets.
    All interested persons are invited to file post-technical
conference comments on the issues raised during the technical
conference, including the questions listed in the Supplemental Notice
of Technical Conference issued February 24, 2021, and on the questions
listed in the attachment to this Notice. Commenters need not answer all
of the questions but are encouraged to organize responses using the
numbering and sequencing in the Supplemental Notice and the attached
questions. In addition, commenters are invited to reference material
previously filed in this docket, including the technical conference
transcript and submitted opening remarks, but are encouraged to avoid
repetition or replication of previous material. Comments must be
submitted on or before 45 days from the date of this Notice.
    Comments may be filed electronically via the internet.\1\
Instructions are available on the Commission's website http://www.ferc.gov/docs-filing/efiling.asp. For assistance, please contact
FERC Online Support at<EMAIL_ADDRESS>or toll free at 1-
866-208-3676, or for TTY,<PHONE_NUMBER>. Although the Commission
strongly encourages electronic filing, documents may also be paper-
filed. To paper-file, submissions sent via the U.S. Postal Service must
be addressed to: Federal Energy Regulatory Commission, Office of the
Secretary, 888 First Street NE, Washington, DC 20426. Submissions sent
via any other carrier must be addressed to: Federal Energy Regulatory
Commission, Office of the Secretary, 12225 Wilkins Avenue, Rockville,
Maryland 20852.
---------------------------------------------------------------------------

    \1\ See 18 CFR 385.2001(a)(1)(iii).
---------------------------------------------------------------------------

    For more information about this Notice, please contact:

David Bowers (Technical Information), Office of Energy Policy and
Innovation,<PHONE_NUMBER><EMAIL_ADDRESS>Kaleb Lockwood (Legal Information), Office of the General Counsel,
(202) 502-8255<EMAIL_ADDRESS>
    Dated: April 21, 2021.
Kimberly D. Bose,
Secretary.
[FR Doc. 2021-08746 Filed 4-26-21; 8:45 am]
BILLING CODE 6717-01-P