	UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES

  SEQ CHAPTER \h \r 1 Date:		27-May-2009

Subject:	Spinosad/Spinetoram.  Dietary Risk Assessment in Support of the Requested use on Date, Pomegranate, Pineapple, Spice (Subgroup 19B; except black pepper), Hop, Tree Nuts (Crop Group 14), and/or Pistachio.

PC Code:  110003 and 110008	DP Barcode:  358161 and 358164

Decision No.:  400738 and 401004	Registration No.:  62719-541; 62719-545; 62719-282; 62719-292

Petition No.:  8E7445 and 8E7450	Regulatory Action:  Section 3 Registration and Label Amendment

Risk Assessment Type:  dietary	Case No.:  none

TXR No.:  not applicable	CAS No.:  187166-40-1 and 187166-15-0; 131929-60-7 and 131929-63-0

MRID No:  none	40 CFR:  180.495 and 180.635

Reviewer/To:	Tom Bloem, Chemist

		Risk Assessment Branch 1/Health Effects Division (RAB1/HED; 7509P)

Through:		Nancy Tsaur, Chemist, Risk Assessment Branch III (RAB3)/HED

		Thurston Morton, Chemist, Risk Assessment Branch IV (RAB4)/HED

		Dietary Exposure Science Advisory Council (DESAC)

				George F. Kramer, Ph.D., Senior Chemist

				HED/RAB1 (7509P)

Executive Summary

HED concluded that spinosad (110003) and spinetoram (110008) are toxicologically equivalent (see D331741, P. Shah et al., 20-Sep-2007); therefore, as part of the current assessment, exposures to these compounds were combined.  The chronic dietary risk assessment was conducted using the Dietary Exposure Evaluation Model - Food Consumption Intake Database (DEEM-FCID(, ver. 2.03).  DEEM-FCID( incorporates food consumption data from the United States Department of Agriculture (USDA) Continuing Surveys of Food Intakes by Individuals (CSFII; 1994-1996 and 1998).  Acute and cancer analyses were not conducted as toxicological effects attributable to a single dose were not identified and spinetoram and spinosad are classified as not likely to be carcinogens (cancer risk assessment is not required).

The chronic analysis assumed 100% crop treated for all food crop commodities; average field-trial residues for apple, Brassica leafy vegetables, citrus, fruiting vegetables, herbs, banana, and strawberry; tolerance-level residues for the remaining food crop commodities; DEEM™ (ver. 7.81) default processing factors for all commodities excluding orange juice, field corn (meal, starch, flour, and oil), grape juice, and wheat (flour and germ) where the spinosad processing factors were assumed; and modeled drinking water estimates.  Residues in livestock were refined through the incorporation of a refined dietary burden (average feed-crop residues and percent crop treated estimates) and through the incorporation of average residues from the feeding and dermal magnitude of the residue studies.  The resulting chronic exposure estimates do not exceed HED's level of concern (≤95% chronic population adjusted dose (cPAD); children 1-2 years old were the most highly exposed subpopulation).

I.  Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED concluded will result in no unreasonable adverse health effects).  This dose is referred to as the PAD.  The PAD is equivalent to the reference dose (RfD) divided by the Food Quality Protection Act (FQPA) Safety Factor (SF).  For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site:  “Available Information on Assessing Exposure from Pesticides, A User’s Guide,” 21-Jun-2000, web link:      HYPERLINK "http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf"  http://www.epa.gov/fedrgstr/ EPA-PEST/2000/July/Day-12/6061.pdf ; or see SOP 99.6 (20-Aug-1999).  The most recent spinosad/spinetoram dietary exposure analysis can be found in D354053 (T. Bloem, 26-Jun-2008).

II.  Residue Information

Residues of Concern in Plants and Livestock:  HED concluded that spinosad (consists of two related active ingredients:  spinosyn A and spinosyn D; PC code 110003) and spinetoram (consists of two related active ingredients:  XDE-175-J and XDE-175-L; PC Code:  110008) are toxicologically equivalent (see D331741, P. Shah et al., 20-Sep-2007); therefore, as part of the current assessment, exposures to these compounds were combined.  The residues of concern in plants, livestock, and water following application of spinetoram or spinosad are as described in Tables 1 and 2, respectively.

Table 1:  Residues for Tolerance Expression and Risk Assessment for Spinetoram (see D331741, P. Shah et al., 20-Sep-2007 for more information).

Matrix	Residues included in Risk Assessment	Residues included in Tolerance Expression

Plants1	XDE-175-J, XDE-175-L, ND-J, and NF-J	XDE-175-J, XDE-175-L, ND-J, and NF-J

Ruminant1,2	XDE-175-J, XDE-175-L, ND-J, and NF-J	XDE-175-J, XDE-175-L, ND-J, and NF-J

Hen1,3	XDE-175-J, XDE-175-L, ND-J, NF-J, 3'-O-deethyl-175-J, 3'-O-deethyl-175-L, and O-demethyl-175-L2	XDE-175-J, XDE-175-L, ND-J, and NF-J

Rotational Crops1	can not be determined from the available data

Drinking Water1	since identified or partially identified degradates in the fate studies contained the major ring structures of the parent compound, a total residue method was used in modeling	--

1  See D331741 (P. Shah et al., 20-Sep-2007) for more information.

2  Feeding studies should employ dosing with parent only (XDE-175-J and XDE-175-L) and should monitor for the residues of concern for risk assessment.

3  O-demethyl-175-L is either 2’-O-demethyl-175-L or 4’-O-demethyl-175-L or a mixture of both.

Table 2:  Residues for Tolerance Expression and Risk Assessment for Spinosad.

Matrix	Residues included in Risk Assessment	Residues included in Tolerance Expression

Plants1	spinosyn A and D	spinosyn A and D

Livestock1	spinosyn A and D	spinosyn A and D

Rotational Crops1	spinosyn A and D	spinosyn A and D

Drinking Water2	total spinosad	--

Fish/Shellfish3	adjustment of the TRRs in the edible tissues from the spinosyn A bioconcentration study (19 ppb data) for the EFED water concentration resulting from the mosquito larvicide use	spinosyn A and D

1  See D243816 (G. Herndon, 3-Mar-1998) and D264984 (W. Donovan, 14-Jun-2002) for more information.

2  See HED risk assessment D316077 (T. Bloem et al., 2-Aug-2006) for more information.

3  HED notes that these conclusions are appropriate for this mosquito larvicide petition only and will be reevaluated if the petitioner alters the aquatic application scenario; see D316077 (T. Bloem et al., 2-Aug-2006) for more information.

Tolerances Recommended as a Result of the Proposed Use:  The petitioner proposed the following:  (1) spinosad (D358163, T. Bloem, 27-May-2009)- registration for application to date and pomegranate and reduction in the preharvest interval (PHI) for tree nuts (crop group 14) and pistachio and (2) spinetoram (D358160, T. Bloem, 27-May-2009) - registration for application to date, pomegranate, pineapple, spice (subgroup 19B; except black pepper), and hop and reduction in the preharvest interval (PHI) for tree nuts (crop group 14) and pistachio.  In addition, the petitioner submitted data addressing deficiencies identified in an earlier review (D357703, T. Bloem, 28-April-2009).  Based on these uses, HED concluded that the following tolerances are appropriate:  (1) spinosad - almond, hulls - 19 ppm; nut, tree, group 14 - 0.10 ppm; pistachio - 0.10 ppm; date - 0.10 ppm; pomegranate - 0.30 ppm; citrus, oil - 23 ppm; and vegetable, leafy, except Brassica, group 4 - 10 ppm and (2) spinetoram - almond, hulls - 19 ppm; nut, tree, group 14 - 0.10 ppm; pistachio - 0.10 ppm; date - 0.10 ppm; pomegranate - 0.30 ppm; pineapple - 0.04 ppm; pineapple, processed waste - 0.15 ppm; spice, subgroup 19B, except black pepper - 1.7 ppm; hop, dried cones - 22 ppm; citrus, oil - 23 ppm; and vegetable, leafy, except Brassica, group 4 - 10 ppm.

Food Residues used in the Chronic Analysis:  HED concluded that spinosad and spinetoram are toxicologically equivalent and that exposures to these compounds should be combined (D331741, P. Shah et al., 20-Sep-2007).  The current analysis assumed 100% crop treated for all food crop commodities; average spinosad field-trial residues for apple, Brassica leafy vegetables, citrus, fruiting vegetables, herbs, banana, and strawberry (see Table 3 for average residues); spinosad tolerance-level residues for the remaining food crop commodities (40 CFR 180.495); spinosad residue estimates for fish/shellfish (D316078, T. Bloem, 2-Aug-2006; residues of spinetoram are not expected in fish/shellfish); DEEM™ (ver. 7.81) default processing factors for all commodities excluding orange juice, field corn (meal, starch, flour, and oil), grape juice, and wheat (flour and germ) where the spinosad processing factors were assumed; previously calculated spinosad egg and poultry and hog tissue estimates (see Table 3); and spinosad residues in ruminant and milk (see Table 3).  HED concludes that these assumptions are appropriate for combined spinosad and spinetoram residues for the following reasons:

(1)  Spinosad is registered for application to all of the crops that spinetoram is registered for application to with similar preharvest and retreatment intervals and application rates ≥ to the spinetoram application rates.  Based on the spinosad and spinetoram application scenarios, the nearly identical structure for spinosad and spinetoram, and the side-by-side spinosad and spinetoram residue data which resulted in spinetoram residues ≤ spinosad residues, HED concluded that translation of the spinosad residue data to spinetoram was acceptable (D325387, T. Bloem, 12-Sep-2007).  Since both products control the same pest species, HED concludes that it is unlikely that spinetoram and spinosad will be applied to the same crop.  Therefore, HED concludes that the spinosad residue data are an acceptable estimate for potential spinosad or spinetoram residues.

 spinetoram processing data and concluded that DEEM™ (ver. 7.81) default processing factors should be assumed pending the submission of these data (D325387, T. Bloem, 17-Sep-2007).  The petitioner submitted the requested data and HED concluded that the spinosad processing factors are adequate for both spinosad and spinetoram (D357703, T. Bloem, 28-Apr-2009).

(3)  The spinosad poultry tolerances are ≥3.3x the HED-recommended spinetoram tolerances.  Since these tolerances are based on maximum residues and 100% crop treated and since the metabolites included as spinetoram residues of concern in hen are likely to be significantly less that parent (based on the metabolism study), HED concludes that the spinosad tolerances are an adequate estimate of combined spinosad and spinetoram residues in poultry commodities for a chronic analysis.

(4)  The spinosad hog tissue residue estimates are based on consumption of spinosad treated feed commodities and from the registered spinosad premise treatment application scenario (see Table 3).  The hog dietary burden was calculated using spinosad percent crop treated estimates and average spinosad field-trial residues.  Spinosad treated feed contributes ≤23% of the total spinosad hog tissue residue estimates (remaining derived from premise treatment) with nearly 100% of this quantity being derived from the post-harvest cereal grain application scenario.

HED concludes that the spinosad hog tissue residue estimates are an adequate estimate of combined spinosad and spinetoram residues for the following reasons:  (a) post-harvest cereal grain and hog premise application scenarios are not requested for spinetoram and (b) the spinosad transfer coefficients are greater than those calculated from the 37.85 ppm single level spinetoram feeding study (47030801.der.doc).  Table 3 contains a summary of the hog tissue residue estimates.

(5)  Beef and dairy cattle dietary burdens to combined spinosad and spinetoram were previously calculated (D354053, T. Bloem, 26-Jun-2008).  Based on the revised Table 1 feedstuffs (OPPTS 860.1000), the only feed item associated with the current petition is almond hulls which are fed to only dairy cattle (roughage; 10% of the diet; 90% dry matter).  Almond hulls do not need to be included in the dairy cattle dietary burden as the contribution from this commodity is 0.30 ppm (100% crop treated and average residues assumed) which is less than the roughage commodities included in the previously calculated dietary burden calculations.  Using the ruminant dietary burdens, residues in ruminant tissue and milk were calculated using the results from the spinosad ruminant feeding study.  As stated above, the spinosad transfer coefficients are greater than those calculated from the 37.85 ppm single-level spinetoram feeding study (47030801.der.doc).  The residues resulting from dietary exposure were then added to the expected residues resulting from the spinosad dermal use and the proposed spinosad ear tag use (spinetoram is not registered for dermal or ear tag use).  Table 3 contains a summary of the beef and dairy cattle residue estimates.

Table 3:  Summary of Refined Combined Spinosyn A and D Residue Estimates Used in the Analysis.

crop group/matrix	crop/commodity	residue (ppm)	reference

refined food crop residues

citrus	grapefruit	0.057	D237752, G. Herndon, 2-Mar-1998; applied to the remaining crops in this crop group using SOP 2000.1; orange juice processing factor included (0.1x).

	lemon	0.068

orange	0.085

	fruiting vegetable	tomato	0.041	D232203, G. Herndon, 2-Mar-1998; applied to the remaining crops in this crop group using SOP 2000.1

	pepper (bell)	0.054

pepper (nonbell)	0.110

	pome fruit	apple	0.026	D228434, S. Willett, 23-Jan-1997; applied to the remaining crops in this crop group using SOP 2000.1

Brassica leafy vegetables	broccoli	0.313	D228434, S. Willett, 23-Jan-1997; applied to the remaining crops in this crop group using SOP 2000.1

	cabbage without wrapper leaves	0.081

mustard greens	3.506

	herbs	fresh	1.200	D278777, W. Donovan, 10-Jul-2002; D312374, T. Bloem, 20-July-2005

	dried	13.920

	cereal grain	corn grain	0.510	Average residues following post-harvest spinosad treatment of the grain (D304201, W. Cutchin, 13-Oct-2004); HED notes that foliar application of spinosad to cereal grains is also registered resulting in <LOQ residues in grain; therefore, HED concludes that the average residues resulting from only the post harvest treatment are acceptable.  The following corn  and wheat processing factors were included (D304201, W. Cutchin, 13-Oct-2004):  corn meal - 0.26x; corn flour - 0.22x, corn oil - 1.2x, corn starch - <0.01x, wheat flour - 0.34x, and wheat germ - 0.72x.

	wheat grain	0.551

barley grain	0.652

oat grain	0.495

rice grain	0.664

	--	banana	0.084	D312374, T. Bloem, 20-Jul-2005; D323723, T. Bloem, 2-Feb-2006

--	strawberry	0.235	45244701.der.wpd

--	grape	0.15	D281616, W. Donovan, 15-Aug-2002; grape juice processing factor included (3.41x).

refined milk/ruminant/hog residues

milk	whole	0.207	See D354053 (T. Bloem, 26-June-2008) for derivation of these estimates; the ruminant milk and tissue residue estimates include a contribution from dietary exposure and from the feed through, dermal, and ear tag uses.

	fat	2.588

skim	0.077

	ruminant	meat	0.113

fat	2.219

meat byproduct	0.385

kidney	0.385

liver	0.615

	hog	meat	0.314	See D319957 (T. Bloem, 24-Aug-2005) for derivation of these estimates; the hog residue estimates include a contribution from dietary exposure and dermal exposure resulting from the premise treatment (D264984, W. Donovan, 14-Jun-2002; D321764, T. Bloem, 2-Feb-2006) using the cattle dermal magnitude of the residues data (pour-on treatment) as a conservative surrogate.

	meat byproducts	1.052

fat	3.518

kidney	1.052

liver	1.357

III.  Water Data

Drinking water residues were incorporated directly into the chronic dietary analyses (“water, direct, all sources” and “water, indirect, all sources”) and were provided by the Environmental Fate and Effects Division (EFED).  EFED concluded that the previously provided spinetoram (D325409, L. Liu, 14-May-2007) and spinosad (D331271, R. Parker, 28-July-2006) estimates were acceptable for the current use.  EFED generated the surface and ground water estimates using the FQPA Index Reservoir Screening Tool (FIRST) and Screening Concentration In Ground Water (SCIGROW) models, respectively.  Table 4 is a summary of the modeled water concentrations.  Based on these estimates, the chronic analysis assumed a water residue estimate of 10.5 ppb.  The models and their description are available at the EPA internet site:   HYPERLINK "http://www.epa.gov/ oppefed1/models/water/"  http://www.epa.gov/ oppefed1/models/water/ .

Table 4:  Estimated Drinking Water Concentrations for Spinosad/Spinetoram (ppb).

	Acute	Chronic	Long-term average

spinosad (turf application scenario; 4 x 0.4 lb ai/acre; RTI = 7 days; 87% of the watershed is treated)

surface	34.5	10.5	--

ground	1.1	1.1	1.1

spinetoram (turf and fire ant mound application; 1 x 0.454 lb ai/acre; 100% of the watershed is treated)

surface	14.419	6.171	--

ground	0.072	0.072	0.072

IV.  DEEM-FCID( Program and Consumption Information

 were conducted using DEEM-FCID™ (Version 2.03), which incorporates consumption data from USDA’s CSFII, 1994-1996 and 1998.  The 1994-96, 98 data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  Consumption data are averaged for the entire U.S. population and within population subgroups for chronic exposure assessment.

For chronic exposure and risk assessment, an estimate of the residue level in each food or food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form.  The resulting residue consumption estimate for each food/food form is summed with the residue consumption estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD.  This procedure is performed for each population subgroup.

V.  Toxicological Information

HED concluded that spinosad (110003) and spinetoram (110008) are toxicologically equivalent and that exposures to these compounds should be combined (D331741, P. Shah et al., 20-Sep-2007).  The following is a summary of the dietary endpoints chosen by HED for dietary risk assessment (see human-health risk assessment for rationale; D331741, P. Shah et al., 20-Sep-2007).  Based on the toxicological databases, the acceptable residue chemistry and environmental fate databases, and the residue assumptions used in the current assessment, HED concluded that the FQPA SF may be reduced to 1x.

Table 5:  Summary of Toxicological Doses and Endpoints for Spinosad/Spinetoram for Use in Dietary Exposure Assessment.

Exposure

Scenario	Dose Used in Risk

Assessment, UF1	FQPA SF and Endpoint for Risk Assessment	Study and Toxicological Effects

Acute Dietary

(gen. US pop. and all pop. subgroups)	No toxicological effect attributable to a single dose identified. This risk assessment is not required.

Chronic Dietary

(all populations)	Oral NOAEL = 2.49 mg/kg/day

UF1 = 100

cRfD = 0.0249 mg/kg/day	FQPA SF = 1x

cPAD = NOAEL ÷ (UF x FQPA SF) = 0.0249mg/kg/day	Chronic Toxicity Study in Dogs;  LOAEL = M/F 5.36/5.83 mg/kg/day; based on arteritis and necrosis of the arterial walls of the epididymides in males and the thymus, thyroid, larynx, and urinary bladder in females.

Cancer	Classification:  Not likely to be carcinogen; cancer risk assessment is not required

1  NOAEL = no observed adverse effect level; LOAEL = lowest observed adverse effect level; UF = uncertainty factor = intraspecies (10x) and interspecies (10x);  RfD = reference dose = NOAEL ÷ UF.; PAD = RfD ÷ FQPA SF.

VI.  Results/Discussion

f ≤95% cPAD (children 1-2 years old were the most highly exposed population subgroup); therefore, chronic exposure to spinosad/spinetoram does not exceed HED's level of concern.  Table 6 is a summary of the results of the chronic analysis.

Table 6:  Summary of Chronic Dietary (food and water) Exposure and Risk for Spinosad/Spinetoram.

Population Subgroup	cPAD (mg/kg/day)	Chronic

Exposure (mg/kg/day)	%cPAD

General U.S. Population	0.0249	0.011873	48

All Infants (<1 year old)

0.010256	41

Children 1-2 years old

0.023616	95

Children 3-5 years old

0.020963	84

Children 6-12 years old

0.014588	59

Youth 13-19 years old

0.010210	41

Adults 20-49 years old

0.010755	43

Adults 50+ years old

0.010356	42

Females 13-49 years old

0.010246	41

VII.  Characterization of Inputs/Outputs

The chronic analysis is conservative in that it assumed DEEM™ (ver. 7.81) default processing factors for the majority of the food commodities, 100% crop treated for all food crop commodities, and modeled drinking water estimates which assumed 87% of the watershed is treated.  HED notes that residues in livestock were refined through the incorporation of a refined dietary burden (average feed-crop residues and projected percent crop or percent crop treated estimates for some feed commodities) and through the incorporation of average milk residues from the ruminant dermal magnitude of the residue study.  The following additional refinements are possible:

(1) Incorporation of combined spinosad and spinetoram percent crop treated estimates for the food crop commodities (100% crop treated currently assumed for all food crop commodities).

(2) Refinement in the fish/shellfish residue estimates.  Fish/shellfish are included as spinosad is currently registered for application as a mosquito larvicide (direct application to water); the current fish/shellfish residue estimates are based on a 489 ppb water concentration which assumed an entire water body is treated, uniform 10 cm depth, and no inflow/outflow.

(3) Refinement in the poultry residue estimates (tolerance-level residues are currently assumed).

VIII.  Conclusions

HED concluded that spinosad and spinetoram are toxicologically equivalent (D331741, P. Shah et al., 20-Sep-2007); therefore, as part of the current assessment, exposures to these compounds were combined.  The chronic dietary risk assessment was conducted using DEEM-FCID( (ver. 2.03).  DEEM-FCID( incorporates the USDA CSFII (1994-1996 and 1998).  Acute and cancer analyses were not conducted as toxicological effects attributable to a single dose were not identified and spinetoram and spinosad are classified as not likely to be carcinogens (cancer risk assessment is not required).

 (≤95% cPAD; children 1-2 years old were the most highly exposed subpopulation).

Attachment 1:  DEEM-FCID( chronic residue file.

Attachment 2:  DEEM-FCID( chronic exposure estimates.

cc with all attachments: G. Larocca/B. Akinlosotu (RD; RM 13)

T. Bloem:S10945:PY1:(703)605-0217:7509P

Attachment 1:  DEEM-FCID( chronic residue file.

Filename: C:\Documents and Settings\tbloem\spinetoram\pineapple, date, pomegranate, hop, subgroup 19B, and revised PHI fro tree nuts\110003c.R98

Chemical: spinosad

RfD(Chronic): .0249 mg/kg bw/day  NOEL(Chronic): 2.49 mg/kg bw/day

RfD(Acute): 0 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day

Date created/last modified: 05-19-2009/09:43:04/8          Program ver. 2.03

Comment: 10x interspecies; 10x intraspecies; 1x FQPA SF

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

01010500 1AB  Beet, garden, roots                0.100000   1.000  1.000

01010501 1AB  Beet, garden, roots-babyfood       0.100000   1.000  1.000

01010520 1A   Beet, sugar                        0.100000   1.000  1.000

01010521 1A   Beet, sugar-babyfood               0.100000   1.000  1.000

01010530 1A   Beet, sugar, molasses              0.750000   1.000  1.000

01010531 1A   Beet, sugar, molasses-babyfood     0.750000   1.000  1.000

01010670 1AB  Burdock                            0.100000   1.000  1.000

01010780 1AB  Carrot                             0.100000   1.000  1.000

01010781 1AB  Carrot-babyfood                    0.100000   1.000  1.000

01010790 1AB  Carrot, juice                      0.100000   1.000  1.000

01010840 1AB  Celeriac                           0.100000   1.000  1.000

01011000 1AB  Chicory, roots                     0.100000   1.000  1.000

01011680 1AB  Ginseng, dried                     0.100000   1.000  1.000

01011900 1AB  Horseradish                        0.100000   1.000  1.000

01012500 1AB  Parsley, turnip rooted             0.100000   1.000  1.000

01012510 1AB  Parsnip                            0.100000   1.000  1.000

01012511 1AB  Parsnip-babyfood                   0.100000   1.000  1.000

01013140 1AB  Radish, roots                      0.100000   1.000  1.000

01013160 1AB  Radish, Oriental, roots            0.100000   1.000  1.000

01013270 1AB  Rutabaga                           0.100000   1.000  1.000

01013310 1AB  Salsify, roots                     0.100000   1.000  1.000

01013880 1AB  Turnip, roots                      0.100000   1.000  1.000

01030150 1CD  Arrowroot, flour                   0.100000   1.000  1.000

01030151 1CD  Arrowroot, flour-babyfood          0.100000   1.000  1.000

01030170 1CD  Artichoke, Jerusalem               0.100000   1.000  1.000

01030820 1CD  Cassava                            0.100000   1.000  1.000

01030821 1CD  Cassava-babyfood                   0.100000   1.000  1.000

01031390 1CD  Dasheen, corm                      0.100000   1.000  1.000

01031660 1CD  Ginger                             0.100000   1.000  1.000

01031661 1CD  Ginger-babyfood                    0.100000   1.000  1.000

01031670 1CD  Ginger, dried                      0.100000   1.000  1.000

01032960 1C   Potato, chips                      0.100000   1.000  1.000

01032970 1C   Potato, dry (granules/ flakes)     0.100000   6.500  1.000

01032971 1C   Potato, dry (granules/ flakes)-b   0.100000   6.500  1.000

01032980 1C   Potato, flour                      0.100000   1.000  1.000

01032981 1C   Potato, flour-babyfood             0.100000   1.000  1.000

01032990 1C   Potato, tuber, w/peel              0.100000   1.000  1.000

01032991 1C   Potato, tuber, w/peel-babyfood     0.100000   1.000  1.000

01033000 1C   Potato, tuber, w/o peel            0.100000   1.000  1.000

01033001 1C   Potato, tuber, w/o peel-babyfood   0.100000   1.000  1.000

01033660 1CD  Sweet potato                       0.100000   1.000  1.000

01033661 1CD  Sweet potato-babyfood              0.100000   1.000  1.000

01033710 1CD  Tanier, corm                       0.100000   1.000  1.000

01033870 1CD  Turmeric                           0.100000   1.000  1.000

01034060 1CD  Yam, true                          0.100000   1.000  1.000

01034070 1CD  Yam bean                           0.100000   1.000  1.000

02000510 2    Beet, garden, tops                10.000000   1.000  1.000

02001010 2    Chicory, tops                     10.000000   1.000  1.000

02001400 2    Dasheen, leaves                   10.000000   1.000  1.000

02003150 2    Radish, tops                      10.000000   1.000  1.000

02003170 2    Radish, Oriental, tops            10.000000   1.000  1.000

02003320 2    Salsify, tops                     10.000000   1.000  1.000

03001640 3    Garlic                             0.100000   1.000  1.000

03001650 3    Garlic, dried                      0.100000   1.000  1.000

03001651 3    Garlic, dried-babyfood             0.100000   1.000  1.000

03001980 3    Leek                               0.100000   1.000  1.000

03002370 3    Onion, dry bulb                    0.100000   1.000  1.000

03002371 3    Onion, dry bulb-babyfood           0.100000   1.000  1.000

03002380 3    Onion, dry bulb, dried             0.100000   9.000  1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.100000   9.000  1.000

03002390 3    Onion, green                       2.000000   1.000  1.000

03003380 3    Shallot                            0.100000   1.000  1.000

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

04013130 4A   Radicchio                         10.000000   1.000  1.000

04013550 4A   Spinach                           10.000000   1.000  1.000

04013551 4A   Spinach-babyfood                  10.000000   1.000  1.000

04020760 4B   Cardoon                           10.000000   1.000  1.000

04020850 4B   Celery                            10.000000   1.000  1.000

04020851 4B   Celery-babyfood                   10.000000   1.000  1.000

04020860 4B   Celery, juice                     10.000000   1.000  1.000

04020870 4B   Celtuce                           10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

04023670 4B   Swiss chard                       10.000000   1.000  1.000

05010610 5A   Broccoli                           0.313000   1.000  1.000

05010611 5A   Broccoli-babyfood                  0.313000   1.000  1.000

05010620 5A   Broccoli, Chinese                  0.313000   1.000  1.000

05010640 5A   Brussels sprouts                   0.081000   1.000  1.000

05010690 5A   Cabbage                            0.081000   1.000  1.000

05010710 5A   Cabbage, Chinese, napa             0.081000   1.000  1.000

05010720 5A   Cabbage, Chinese, mustard          0.313000   1.000  1.000

05010830 5A   Cauliflower                        0.313000   1.000  1.000

05011960 5A   Kohlrabi                           0.081000   1.000  1.000

05020630 5B   Broccoli raab                      3.506000   1.000  1.000

05020700 5B   Cabbage, Chinese, bok choy         3.506000   1.000  1.000

05021170 5B   Collards                           3.506000   1.000  1.000

05021940 5B   Kale                               3.506000   1.000  1.000

05022290 5B   Mustard greens                     3.506000   1.000  1.000

05023180 5B   Rape greens                        3.506000   1.000  1.000

05023890 5B   Turnip, greens                     3.506000   1.000  1.000

06003470 6    Soybean, seed                      0.040000   1.000  1.000

06003480 6    Soybean, flour                     0.040000   1.000  1.000

06003481 6    Soybean, flour-babyfood            0.040000   1.000  1.000

06003490 6    Soybean, soy milk                  0.040000   1.000  1.000

06003491 6    Soybean, soy milk-babyfood or in   0.040000   1.000  1.000

06003500 6    Soybean, oil                       0.040000   1.000  1.000

06003501 6    Soybean, oil-babyfood              0.040000   1.000  1.000

06010430 6A   Bean, snap, succulent              0.300000   1.000  1.000

06010431 6A   Bean, snap, succulent-babyfood     0.300000   1.000  1.000

06012570 6A   Pea, edible podded, succulent      0.300000   1.000  1.000

06020310 6B   Bean, broad, succulent             0.040000   1.000  1.000

06020330 6B   Bean, cowpea, succulent            0.040000   1.000  1.000

06020370 6B   Bean, lima, succulent              0.040000   1.000  1.000

06022550 6B   Pea, succulent                     0.040000   1.000  1.000

06022551 6B   Pea, succulent-babyfood            0.040000   1.000  1.000

06022590 6B   Pea, pigeon, succulent             0.040000   1.000  1.000

06030300 6C   Bean, black, seed                  0.040000   1.000  1.000

06030320 6C   Bean, broad, seed                  0.040000   1.000  1.000

06030340 6C   Bean, cowpea, seed                 0.040000   1.000  1.000

06030350 6C   Bean,  great northern, seed        0.040000   1.000  1.000

06030360 6C   Bean, kidney, seed                 0.040000   1.000  1.000

06030380 6C   Bean, lima, seed                   0.040000   1.000  1.000

06030390 6C   Bean, mung, seed                   0.040000   1.000  1.000

06030400 6C   Bean, navy, seed                   0.040000   1.000  1.000

06030410 6C   Bean, pink, seed                   0.040000   1.000  1.000

06030420 6C   Bean, pinto, seed                  0.040000   1.000  1.000

06030980 6C   Chickpea, seed                     0.040000   1.000  1.000

06030981 6C   Chickpea, seed-babyfood            0.040000   1.000  1.000

06030990 6C   Chickpea, flour                    0.040000   1.000  1.000

06031820 6C   Guar, seed                         0.040000   1.000  1.000

06031821 6C   Guar, seed-babyfood                0.040000   1.000  1.000

06032030 6C   Lentil, seed                       0.040000   1.000  1.000

06032560 6C   Pea, dry                           0.040000   1.000  1.000

06032561 6C   Pea, dry-babyfood                  0.040000   1.000  1.000

06032580 6C   Pea, pigeon, seed                  0.040000   1.000  1.000

08001480 8    Eggplant                           0.054000   1.000  1.000

08002340 8    Okra                               0.110000   1.000  1.000

08002700 8    Pepper, bell                       0.054000   1.000  1.000

08002701 8    Pepper, bell-babyfood              0.054000   1.000  1.000

08002710 8    Pepper, bell, dried                0.054000   1.000  1.000

08002711 8    Pepper, bell, dried-babyfood       0.054000   1.000  1.000

08002720 8    Pepper, nonbell                    0.110000   1.000  1.000

08002721 8    Pepper, nonbell-babyfood           0.110000   1.000  1.000

08002730 8    Pepper, nonbell, dried             0.110000   1.000  1.000

08003740 8    Tomatillo                          0.041000   1.000  1.000

08003750 8    Tomato                             0.041000   1.000  1.000

08003751 8    Tomato-babyfood                    0.041000   1.000  1.000

08003760 8    Tomato, paste                      0.041000   5.400  1.000

08003761 8    Tomato, paste-babyfood             0.041000   5.400  1.000

08003770 8    Tomato, puree                      0.041000   3.300  1.000

08003771 8    Tomato, puree-babyfood             0.041000   3.300  1.000

08003780 8    Tomato, dried                      0.041000  14.300  1.000

08003781 8    Tomato, dried-babyfood             0.041000  14.300  1.000

08003790 8    Tomato, juice                      0.041000   1.500  1.000

09010750 9A   Cantaloupe                         0.300000   1.000  1.000

09010800 9A   Casaba                             0.300000   1.000  1.000

09011870 9A   Honeydew melon                     0.300000   1.000  1.000

09013990 9A   Watermelon                         0.300000   1.000  1.000

09014000 9A   Watermelon, juice                  0.300000   1.000  1.000

09020210 9B   Balsam pear                        0.300000   1.000  1.000

09020880 9B   Chayote, fruit                     0.300000   1.000  1.000

09021020 9B   Chinese waxgourd                   0.300000   1.000  1.000

09021350 9B   Cucumber                           0.300000   1.000  1.000

09023080 9B   Pumpkin                            0.300000   1.000  1.000

09023090 9B   Pumpkin, seed                      0.300000   1.000  1.000

09023560 9B   Squash, summer                     0.300000   1.000  1.000

09023561 9B   Squash, summer-babyfood            0.300000   1.000  1.000

09023570 9B   Squash, winter                     0.300000   1.000  1.000

09023571 9B   Squash, winter-babyfood            0.300000   1.000  1.000

10001060 10   Citrus citron                      0.085000   1.000  1.000

10001070 10   Citrus hybrids                     0.085000   1.000  1.000

10001080 10   Citrus, oil                       23.000000   1.000  1.000

10001800 10   Grapefruit                         0.057000   1.000  1.000

10001810 10   Grapefruit, juice                  0.057000   2.100  1.000

10001970 10   Kumquat                            0.085000   1.000  1.000

10001990 10   Lemon                              0.068000   1.000  1.000

10002000 10   Lemon, juice                       0.068000   2.000  1.000

10002001 10   Lemon, juice-babyfood              0.068000   2.000  1.000

10002010 10   Lemon, peel                        0.068000   1.000  1.000

10002060 10   Lime                               0.068000   1.000  1.000

10002070 10   Lime, juice                        0.068000   2.000  1.000

10002071 10   Lime, juice-babyfood               0.068000   2.000  1.000

10002400 10   Orange                             0.085000   1.000  1.000

10002410 10   Orange, juice                      0.085000   0.100  1.000

10002411 10   Orange, juice-babyfood             0.085000   0.100  1.000

10002420 10   Orange, peel                       0.085000   1.000  1.000

10003070 10   Pummelo                            0.057000   1.000  1.000

10003690 10   Tangerine                          0.085000   1.000  1.000

10003700 10   Tangerine, juice                   0.085000   2.300  1.000

11000070 11   Apple, fruit with peel             0.026000   1.000  1.000

11000080 11   Apple, peeled fruit                0.026000   1.000  1.000

11000081 11   Apple, peeled fruit-babyfood       0.026000   1.000  1.000

11000090 11   Apple, dried                       0.026000   8.000  1.000

11000091 11   Apple, dried-babyfood              0.026000   8.000  1.000

11000100 11   Apple, juice                       0.026000   1.300  1.000

11000101 11   Apple, juice-babyfood              0.026000   1.300  1.000

11000110 11   Apple, sauce                       0.026000   1.000  1.000

11000111 11   Apple, sauce-babyfood              0.026000   1.000  1.000

11001290 11   Crabapple                          0.026000   1.000  1.000

11002100 11   Loquat                             0.200000   1.000  1.000

11002660 11   Pear                               0.200000   1.000  1.000

11002661 11   Pear-babyfood                      0.200000   1.000  1.000

11002670 11   Pear, dried                        0.200000   6.250  1.000

11002680 11   Pear, juice                        0.200000   1.000  1.000

11002681 11   Pear, juice-babyfood               0.200000   1.000  1.000

11003100 11   Quince                             0.200000   1.000  1.000

12000120 12   Apricot                            0.200000   1.000  1.000

12000121 12   Apricot-babyfood                   0.200000   1.000  1.000

12000130 12   Apricot, dried                     0.200000   6.000  1.000

12000140 12   Apricot, juice                     0.200000   1.000  1.000

12000141 12   Apricot, juice-babyfood            0.200000   1.000  1.000

12000900 12   Cherry                             0.200000   1.000  1.000

12000901 12   Cherry-babyfood                    0.200000   1.000  1.000

12000910 12   Cherry, juice                      0.200000   1.500  1.000

12000911 12   Cherry, juice-babyfood             0.200000   1.500  1.000

12002300 12   Nectarine                          0.200000   1.000  1.000

12002600 12   Peach                              0.200000   1.000  1.000

12002601 12   Peach-babyfood                     0.200000   1.000  1.000

12002610 12   Peach, dried                       0.200000   7.000  1.000

12002611 12   Peach, dried-babyfood              0.200000   7.000  1.000

12002620 12   Peach, juice                       0.200000   1.000  1.000

12002621 12   Peach, juice-babyfood              0.200000   1.000  1.000

12002850 12   Plum                               0.200000   1.000  1.000

12002851 12   Plum-babyfood                      0.200000   1.000  1.000

12002860 12   Plum, prune, fresh                 0.200000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000  1.000

12002870 12   Plum, prune, dried                 0.200000   5.000  1.000

12002871 12   Plum, prune, dried-babyfood        0.200000   5.000  1.000

12002880 12   Plum, prune, juice                 0.200000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400  1.000

13010550 13A  Blackberry                         0.700000   1.000  1.000

13010560 13A  Blackberry, juice                  0.700000   1.000  1.000

13010561 13A  Blackberry, juice-babyfood         0.700000   1.000  1.000

13010580 13A  Boysenberry                        0.700000   1.000  1.000

13011420 13A  Dewberry                           0.700000   1.000  1.000

13012080 13A  Loganberry                         0.700000   1.000  1.000

13013200 13A  Raspberry                          0.700000   1.000  1.000

13013201 13A  Raspberry-babyfood                 0.700000   1.000  1.000

13013210 13A  Raspberry, juice                   0.700000   1.000  1.000

13013211 13A  Raspberry, juice-babyfood          0.700000   1.000  1.000

13020570 13B  Blueberry                          0.250000   1.000  1.000

13020571 13B  Blueberry-babyfood                 0.250000   1.000  1.000

13021360 13B  Currant                            0.250000   1.000  1.000

13021370 13B  Currant, dried                     0.250000   1.000  1.000

13021490 13B  Elderberry                         0.250000   1.000  1.000

13021740 13B  Gooseberry                         0.250000   1.000  1.000

13021910 13B  Huckleberry                        0.250000   1.000  1.000

14000030 14   Almond                             0.100000   1.000  1.000

14000031 14   Almond-babyfood                    0.100000   1.000  1.000

14000040 14   Almond, oil                        0.100000   1.000  1.000

14000041 14   Almond, oil-babyfood               0.100000   1.000  1.000

14000590 14   Brazil nut                         0.100000   1.000  1.000

14000680 14   Butternut                          0.100000   1.000  1.000

14000810 14   Cashew                             0.100000   1.000  1.000

14000920 14   Chestnut                           0.100000   1.000  1.000

14001550 14   Filbert                            0.100000   1.000  1.000

14001560 14   Filbert, oil                       0.100000   1.000  1.000

14001850 14   Hickory nut                        0.100000   1.000  1.000

14002130 14   Macadamia nut                      0.100000   1.000  1.000

14002690 14   Pecan                              0.100000   1.000  1.000

14002820 14   Pistachio                          0.100000   1.000  1.000

14003910 14   Walnut                             0.100000   1.000  1.000

15000250 15   Barley, pearled barley             0.652000   1.000  1.000

15000251 15   Barley, pearled barley-babyfood    0.652000   1.000  1.000

15000260 15   Barley, flour                      0.652000   1.000  1.000

15000261 15   Barley, flour-babyfood             0.652000   1.000  1.000

15000270 15   Barley, bran                       0.652000   1.000  1.000

15000650 15   Buckwheat                          1.500000   1.000  1.000

15000660 15   Buckwheat, flour                   1.500000   1.000  1.000

15001200 15   Corn, field, flour                 0.510000   0.220  1.000

15001201 15   Corn, field, flour-babyfood        0.510000   0.220  1.000

15001210 15   Corn, field, meal                  0.510000   0.260  1.000

15001211 15   Corn, field, meal-babyfood         0.510000   0.260  1.000

15001220 15   Corn, field, bran                  0.510000   1.000  1.000

15001230 15   Corn, field, starch                0.510000   0.010  1.000

15001231 15   Corn, field, starch-babyfood       0.510000   0.010  1.000

15001240 15   Corn, field, syrup                 0.510000   1.500  1.000

15001241 15   Corn, field, syrup-babyfood        0.510000   1.500  1.000

15001250 15   Corn, field, oil                   0.510000   1.200  1.000

15001251 15   Corn, field, oil-babyfood          0.510000   1.200  1.000

15001260 15   Corn, pop                          0.510000   1.000  1.000

15001270 15   Corn, sweet                        0.040000   1.000  1.000

15001271 15   Corn, sweet-babyfood               0.040000   1.000  1.000

15002260 15   Millet, grain                      1.500000   1.000  1.000

15002310 15   Oat, bran                          0.495000   1.000  1.000

15002320 15   Oat, flour                         0.495000   1.000  1.000

15002321 15   Oat, flour-babyfood                0.495000   1.000  1.000

15002330 15   Oat, groats/rolled oats            0.495000   1.000  1.000

15002331 15   Oat, groats/rolled oats-babyfood   0.495000   1.000  1.000

15003230 15   Rice, white                        0.664000   1.000  1.000

15003231 15   Rice, white-babyfood               0.664000   1.000  1.000

15003240 15   Rice, brown                        0.664000   1.000  1.000

15003241 15   Rice, brown-babyfood               0.664000   1.000  1.000

15003250 15   Rice, flour                        0.664000   1.000  1.000

15003251 15   Rice, flour-babyfood               0.664000   1.000  1.000

15003260 15   Rice, bran                         0.664000   1.000  1.000

15003261 15   Rice, bran-babyfood                0.664000   1.000  1.000

15003280 15   Rye, grain                         1.500000   1.000  1.000

15003290 15   Rye, flour                         1.500000   1.000  1.000

15003440 15   Sorghum, grain                     1.500000   1.000  1.000

15003450 15   Sorghum, syrup                     1.500000   1.000  1.000

15003810 15   Triticale, flour                   1.500000   1.000  1.000

15003811 15   Triticale, flour-babyfood          1.500000   1.000  1.000

15004010 15   Wheat, grain                       0.551000   1.000  1.000

15004011 15   Wheat, grain-babyfood              0.551000   1.000  1.000

15004020 15   Wheat, flour                       0.551000   0.340  1.000

15004021 15   Wheat, flour-babyfood              0.551000   0.340  1.000

15004030 15   Wheat, germ                        0.551000   0.720  1.000

15004040 15   Wheat, bran                        0.551000   1.000  1.000

15004050 15   Wild rice                          1.500000   1.000  1.000

18000020 18   Alfalfa, seed                      0.150000   1.000  1.000

19010280 19A  Basil, fresh leaves                1.200000   1.000  1.000

19010281 19A  Basil, fresh leaves-babyfood       1.200000   1.000  1.000

19010290 19A  Basil, dried leaves               13.920000   1.000  1.000

19010291 19A  Basil, dried leaves-babyfood      13.920000   1.000  1.000

19011030 19A  Chive                             13.920000   1.000  1.000

19011180 19A  Coriander, leaves                  8.000000   1.000  1.000

19011181 19A  Coriander, leaves-babyfood         8.000000   1.000  1.000

19011440 19A  Dillweed                          13.920000   1.000  1.000

19011840 19A  Herbs, other                      13.920000   1.000  1.000

19011841 19A  Herbs, other-babyfood             13.920000   1.000  1.000

19012020 19A  Lemongrass                        13.920000   1.000  1.000

19012200 19A  Marjoram                          13.920000   1.000  1.000

19012201 19A  Marjoram-babyfood                 13.920000   1.000  1.000

19012490 19A  Parsley, dried leaves             13.920000   1.000  1.000

19012491 19A  Parsley, dried leaves-babyfood    13.920000   1.000  1.000

19013340 19A  Savory                            13.920000   1.000  1.000

19021050 19B  Cinnamon                           1.700000   1.000  1.000

19021051 19B  Cinnamon-babyfood                  1.700000   1.000  1.000

19021190 19B  Coriander, seed                    1.700000   1.000  1.000

19021191 19B  Coriander, seed-babyfood           1.700000   1.000  1.000

19021430 19B  Dill, seed                         1.700000   1.000  1.000

19022740 19B  Pepper, black and white            0.020000   1.000  1.000

19022741 19B  Pepper, black and white-babyfood   0.020000   1.000  1.000

19023540 19B  Spices, other                      1.700000   1.000  1.000

19023541 19B  Spices, other-babyfood             1.700000   1.000  1.000

20001630 20   Flaxseed, oil                      0.020000   1.000  1.000

20003190 20   Rapeseed, oil                      0.020000   1.000  1.000

20003191 20   Rapeseed, oil-babyfood             0.020000   1.000  1.000

20003300 20   Safflower, oil                     0.020000   1.000  1.000

20003301 20   Safflower, oil-babyfood            0.020000   1.000  1.000

20003640 20   Sunflower, seed                    0.020000   1.000  1.000

20003650 20   Sunflower, oil                     0.020000   1.000  1.000

20003651 20   Sunflower, oil-babyfood            0.020000   1.000  1.000

21000440 M    Beef, meat                         0.113000   1.000  1.000

21000441 M    Beef, meat-babyfood                0.113000   1.000  1.000

21000450 M    Beef, meat, dried                  0.113000   1.920  1.000

21000460 M    Beef, meat byproducts              0.385000   1.000  1.000

21000461 M    Beef, meat byproducts-babyfood     0.385000   1.000  1.000

21000470 M    Beef, fat                          2.219000   1.000  1.000

21000471 M    Beef,fat-babyfood                  2.219000   1.000  1.000

21000480 M    Beef, kidney                       0.385000   1.000  1.000

21000490 M    Beef, liver                        0.615000   1.000  1.000

21000491 M    Beef, liver-babyfood               0.615000   1.000  1.000

23001690 M    Goat, meat                         0.113000   1.000  1.000

23001700 M    Goat, meat byproducts              0.113000   1.000  1.000

23001710 M    Goat, fat                          2.219000   1.000  1.000

23001720 M    Goat, kidney                       0.385000   1.000  1.000

23001730 M    Goat, liver                        0.615000   1.000  1.000

24001890 M    Horse, meat                        0.113000   1.000  1.000

25002900 M    Pork, meat                         0.314000   1.000  1.000

25002901 M    Pork, meat-babyfood                0.314000   1.000  1.000

25002910 M    Pork, skin                         3.518000   1.000  1.000

25002920 M    Pork, meat byproducts              1.052000   1.000  1.000

25002921 M    Pork, meat byproducts-babyfood     1.052000   1.000  1.000

25002930 M    Pork, fat                          3.518000   1.000  1.000

25002931 M    Pork, fat-babyfood                 3.518000   1.000  1.000

25002940 M    Pork, kidney                       1.052000   1.000  1.000

25002950 M    Pork, liver                        1.357000   1.000  1.000

26003390 M    Sheep, meat                        0.113000   1.000  1.000

26003391 M    Sheep, meat-babyfood               0.113000   1.000  1.000

26003400 M    Sheep, meat byproducts             0.385000   1.000  1.000

26003410 M    Sheep, fat                         2.219000   1.000  1.000

26003411 M    Sheep, fat-babyfood                2.219000   1.000  1.000

26003420 M    Sheep, kidney                      0.385000   1.000  1.000

26003430 M    Sheep, liver                       0.615000   1.000  1.000

27002220 D    Milk, fat                          2.588000   1.000  1.000

27002221 D    Milk, fat - baby food/infant for   2.588000   1.000  1.000

27012230 D    Milk, nonfat solids                0.207000   1.000  1.000

27012231 D    Milk, nonfat solids-baby food/in   0.207000   1.000  1.000

27022240 D    Milk, water                        0.077000   1.000  1.000

27022241 D    Milk, water-babyfood/infant form   0.077000   1.000  1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.207000   1.000  1.000

28002210 M    Meat, game                         0.113000   1.000  1.000

29003120 M    Rabbit, meat                       0.113000   1.000  1.000

40000930 P    Chicken, meat                      0.100000   1.000  1.000

40000931 P    Chicken, meat-babyfood             0.100000   1.000  1.000

40000940 P    Chicken, liver                     0.100000   1.000  1.000

40000950 P    Chicken, meat byproducts           0.100000   1.000  1.000

40000951 P    Chicken, meat byproducts-babyfoo   0.100000   1.000  1.000

40000960 P    Chicken, fat                       1.300000   1.000  1.000

40000961 P    Chicken, fat-babyfood              1.300000   1.000  1.000

40000970 P    Chicken, skin                      1.300000   1.000  1.000

40000971 P    Chicken, skin-babyfood             1.300000   1.000  1.000

50003820 P    Turkey, meat                       0.100000   1.000  1.000

50003821 P    Turkey, meat-babyfood              0.100000   1.000  1.000

50003830 P    Turkey, liver                      0.100000   1.000  1.000

50003831 P    Turkey, liver-babyfood             0.100000   1.000  1.000

50003840 P    Turkey, meat byproducts            0.100000   1.000  1.000

50003841 P    Turkey, meat byproducts-babyfood   0.100000   1.000  1.000

50003850 P    Turkey, fat                        1.300000   1.000  1.000

50003851 P    Turkey, fat-babyfood               1.300000   1.000  1.000

50003860 P    Turkey, skin                       1.300000   1.000  1.000

50003861 P    Turkey, skin-babyfood              1.300000   1.000  1.000

60003010 P    Poultry, other, meat               0.100000   1.000  1.000

60003020 P    Poultry, other, liver              0.100000   1.000  1.000

60003030 P    Poultry, other, meat byproducts    0.100000   1.000  1.000

60003040 P    Poultry, other, fat                1.300000   1.000  1.000

60003050 P    Poultry, other, skin               1.300000   1.000  1.000

70001450 P    Egg, whole                         0.300000   1.000  1.000

70001451 P    Egg, whole-babyfood                0.300000   1.000  1.000

70001460 P    Egg, white                         0.300000   1.000  1.000

70001461 P    Egg, white (solids)-babyfood       0.300000   1.000  1.000

70001470 P    Egg, yolk                          0.300000   1.000  1.000

70001471 P    Egg, yolk-babyfood                 0.300000   1.000  1.000

80001570 F    Fish-freshwater finfish           12.500000   1.000  1.000

80001580 F    Fish-freshwater finfish, farm ra  12.500000   1.000  1.000

80001590 F    Fish-saltwater finfish, tuna      12.500000   1.000  1.000

80001600 F    Fish-saltwater finfish, other     12.500000   1.000  1.000

80001610 F    Fish-shellfish, crustacean        12.500000   1.000  1.000

80001620 F    Fish-shellfish, mollusc           12.500000   1.000  1.000

86010000 O    Water, direct, all sources         0.010500   1.000  1.000

86020000 O    Water, indirect, all sources       0.010500   1.000  1.000

95000010 O    Acerola                            1.500000   1.000  1.000

95000060 O    Amaranth, grain                    1.000000   1.000  1.000

95000160 O    Artichoke, globe                   0.300000   1.000  1.000

95000190 O    Asparagus                          0.200000   1.000  1.000

95000200 O    Avocado                            0.300000   1.000  1.000

95000220 O    Bamboo, shoots                     0.020000   1.000  1.000

95000230 O    Banana                             0.084000   1.000  1.000

95000231 O    Banana-babyfood                    0.084000   1.000  1.000

95000240 O    Banana, dried                      0.084000   3.900  1.000

95000241 O    Banana, dried-babyfood             0.084000   3.900  1.000

95000540 O    Belgium endive                     0.020000   1.000  1.000

95000600 O    Breadfruit                         0.020000   1.000  1.000

95000730 O    Cactus                             0.020000   1.000  1.000

95000740 O    Canistel                           0.300000   1.000  1.000

95000770 O    Carob                              0.020000   1.000  1.000

95000890 O    Cherimoya                          0.300000   1.000  1.000

95001090 O    Cocoa bean, chocolate              0.020000   1.000  1.000

95001100 O    Cocoa bean, powder                 0.020000   1.000  1.000

95001110 O    Coconut, meat                      0.020000   1.000  1.000

95001111 O    Coconut- meat-babyfood             0.020000   1.000  1.000

95001120 O    Coconut, dried                     0.020000   2.100  1.000

95001130 O    Coconut, milk                      0.020000   1.000  1.000

95001140 O    Coconut, oil                       0.020000   1.000  1.000

95001141 O    Coconut, oil-babyfood              0.020000   1.000  1.000

95001150 O    Coffee, roasted bean               0.020000   1.000  1.000

95001160 O    Coffee, instant                    0.020000   1.000  1.000

95001280 O    Cottonseed, oil                    0.040000   1.000  1.000

95001281 O    Cottonseed, oil-babyfood           0.040000   1.000  1.000

95001300 O    Cranberry                          0.040000   1.000  1.000

95001301 O    Cranberry-babyfood                 0.040000   1.000  1.000

95001310 O    Cranberry, dried                   0.040000   1.000  1.000

95001320 O    Cranberry, juice                   0.040000   1.100  1.000

95001321 O    Cranberry, juice-babyfood          0.040000   1.100  1.000

95001410 O    Date                               0.100000   1.000  1.000

95001510 O    Feijoa                             0.300000   1.000  1.000

95001530 O    Fig                                0.100000   1.000  1.000

95001540 O    Fig, dried                         0.100000   1.000  1.000

95001750 O    Grape                              0.150000   1.000  1.000

95001760 O    Grape, juice                       0.150000   3.410  1.000

95001761 O    Grape, juice-babyfood              0.150000   3.410  1.000

95001770 O    Grape, leaves                      0.150000   1.000  1.000

95001780 O    Grape, raisin                      0.150000   4.300  1.000

95001790 O    Grape, wine and sherry             0.150000   3.410  1.000

95001830 O    Guava                              0.300000   1.000  1.000

95001831 O    Guava-babyfood                     0.300000   1.000  1.000

95001860 O    Honey                              0.020000   1.000  1.000

95001861 O    Honey-babyfood                     0.020000   1.000  1.000

95001880 O    Hop                               22.000000   1.000  1.000

95001920 O    Jaboticaba                         0.300000   1.000  1.000

95001930 O    Jackfruit                          0.020000   1.000  1.000

95001950 O    Kiwifruit                          0.020000   1.000  1.000

95002090 O    Longan                             0.300000   1.000  1.000

95002110 O    Lychee                             0.300000   1.000  1.000

95002120 O    Lychee, dried                      0.300000   1.850  1.000

95002140 O    Mamey apple                        0.020000   1.000  1.000

95002150 O    Mango                              0.300000   1.000  1.000

95002151 O    Mango-babyfood                     0.300000   1.000  1.000

95002160 O    Mango, dried                       0.300000   1.000  1.000

95002170 O    Mango, juice                       0.300000   1.000  1.000

95002171 O    Mango, juice-babyfood              0.300000   1.000  1.000

95002180 O    Maple, sugar                       0.020000   1.000  1.000

95002190 O    Maple syrup                        0.020000   1.000  1.000

95002270 O    Mulberry                           0.020000   1.000  1.000

95002280 O    Mushroom                           0.020000   1.000  1.000

95002350 O    Olive                              0.020000   1.000  1.000

95002360 O    Olive, oil                         0.020000   1.000  1.000

95002430 O    Palm heart, leaves                 0.020000   1.000  1.000

95002440 O    Palm, oil                          0.020000   1.000  1.000

95002441 O    Palm, oil-babyfood                 0.020000   1.000  1.000

95002450 O    Papaya                             0.300000   1.000  1.000

95002451 O    Papaya-babyfood                    0.300000   1.000  1.000

95002460 O    Papaya, dried                      0.300000   1.800  1.000

95002470 O    Papaya, juice                      0.300000   1.500  1.000

95002520 O    Passionfruit                       0.300000   1.000  1.000

95002521 O    Passionfruit-babyfood              0.300000   1.000  1.000

95002530 O    Passionfruit, juice                0.300000   1.000  1.000

95002531 O    Passionfruit, juice-babyfood       0.300000   1.000  1.000

95002540 O    Pawpaw                             0.020000   1.000  1.000

95002630 O    Peanut                             0.040000   1.000  1.000

95002640 O    Peanut, butter                     0.040000   1.890  1.000

95002650 O    Peanut, oil                        0.040000   1.000  1.000

95002750 O    Peppermint                         3.500000   1.000  1.000

95002760 O    Peppermint, oil                    3.500000   1.000  1.000

95002770 O    Persimmon                          0.020000   1.000  1.000

95002780 O    Pine nut                           0.020000   1.000  1.000

95002790 O    Pineapple                          0.040000   1.000  1.000

95002791 O    Pineapple-babyfood                 0.040000   1.000  1.000

95002800 O    Pineapple, dried                   0.040000   5.000  1.000

95002810 O    Pineapple, juice                   0.040000   1.700  1.000

95002811 O    Pineapple, juice-babyfood          0.040000   1.700  1.000

95002830 O    Plantain                           0.250000   1.000  1.000

95002840 O    Plantain, dried                    0.250000   3.900  1.000

95002890 O    Pomegranate                        0.300000   1.000  1.000

95003060 O    Psyllium, seed                     0.020000   1.000  1.000

95003110 O    Quinoa, grain                      0.020000   1.000  1.000

95003330 O    Sapote, Mamey                      0.300000   1.000  1.000

95003350 O    Seaweed                            0.020000   1.000  1.000

95003351 O    Seaweed-babyfood                   0.020000   1.000  1.000

95003360 O    Sesame, seed                       0.020000   1.000  1.000

95003361 O    Sesame, seed-babyfood              0.020000   1.000  1.000

95003370 O    Sesame, oil                        0.020000   1.000  1.000

95003371 O    Sesame, oil-babyfood               0.020000   1.000  1.000

95003460 O    Soursop                            0.300000   1.000  1.000

95003510 O    Spanish lime                       0.300000   1.000  1.000

95003520 O    Spearmint                          3.500000   1.000  1.000

95003530 O    Spearmint, oil                     3.500000   1.000  1.000

95003580 O    Starfruit                          0.300000   1.000  1.000

95003590 O    Strawberry                         0.235000   1.000  1.000

95003591 O    Strawberry-babyfood                0.235000   1.000  1.000

95003600 O    Strawberry, juice                  0.235000   1.000  1.000

95003601 O    Strawberry, juice-babyfood         0.235000   1.000  1.000

95003610 O    Sugar apple                        0.300000   1.000  1.000

95003620 O    Sugarcane, sugar                   0.020000   1.000  1.000

95003621 O    Sugarcane, sugar-babyfood          0.020000   1.000  1.000

95003630 O    Sugarcane, molasses                0.020000   1.000  1.000

95003631 O    Sugarcane, molasses-babyfood       0.020000   1.000  1.000

95003680 O    Tamarind                           0.020000   1.000  1.000

95003720 O    Tea, dried                         0.020000   1.000  1.000

95003730 O    Tea, instant                       0.020000   1.000  1.000

95003800 O    Tomato, Tree                       0.020000   1.000  1.000

95003900 O    Vinegar                            0.020000   1.000  1.000

95003980 O    Watercress                         8.000000   1.000  1.000

Attachment 2:  DEEM-FCID( chronic exposure estimates.

U.S. Environmental Protection Agency                                 Ver. 2.00

DEEM-FCID Chronic analysis for SPINOSAD                         (1994-98 data)

Residue file name: C:\Documents and Settings\tbloem\spinetoram\pineapple, date, pomegranate, hop, subgroup 19B, and revised PHI fro tree nuts\110003c.R98   Adjustment factor #2 NOT used.

Analysis Date 06-02-2009/07:35:16     Residue file dated: 05-19-2009/09:43:04/8

Reference dose (RfD, Chronic) = .0249 mg/kg bw/day

COMMENT 1: 10x interspecies; 10x intraspecies; 1x FQPA SF

======================================================================== =======

                    Total exposure by population subgroup

------------------------------------------------------------------------ -------

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(                                         -----------------------------------

          Population                         mg/kg             Percent of

           Subgroup                       body wt/day             Rfd

--------------------------------------   -------------       ---------------

U.S. Population (total)                     0.011873                47.7%

U.S. Population (spring season)             0.012442                50.0%

U.S. Population (summer season)             0.011714                47.0%

U.S. Population (autumn season)             0.011684                46.9%

U.S. Population (winter season)             0.011666                46.9%

Northeast region                            0.012922                51.9%

Midwest region                              0.011436                45.9%

Southern region                             0.010878                43.7%

Western region                              0.012979                52.1%

Hispanics                                   0.011998                48.2%

Non-hispanic whites                         0.011473                46.1%

Non-hispanic blacks                         0.012009                48.2%

Non-hisp/non-white/non-black                0.017755                71.3%

All infants (< 1 year)                      0.010256                41.2%

Nursing infants                             0.004081                16.4%

Non-nursing infants                         0.012599                50.6%

Children 1-6  yrs                           0.021237                85.3%

Children 7-12 yrs                           0.014101                56.6%

Females 13-19 (not preg or nursing)         0.009330                37.5%

Females 20+ (not preg or nursing)           0.010416                41.8%

Females 13-50 yrs                           0.010541                42.3%

Females 13+ (preg/not nursing)              0.009512                38.2%

Females 13+ (nursing)                       0.011193                45.0%

Males 13-19 yrs                             0.011038                44.3%

Males 20+ yrs                               0.010831                43.5%

Seniors 55+                                 0.010233                41.1%

Children 1-2 yrs                            0.023616                94.8%

Children 3-5 yrs                            0.020963                84.2%

Children 6-12 yrs                           0.014588                58.6%

Youth 13-19 yrs                             0.010210                41.0%

Adults 20-49 yrs                            0.010755                43.2%

Adults 50+ yrs                              0.010356                41.6%

Females 13-49 yrs                           0.010246                41.1%

------------------------------------------------------------------------ -------

Spinetoram and Spinosad	Dietary Exposure and Risk Assessment	D358161

Page   PAGE  19  of   NUMPAGES  20