[Federal Register Volume 77, Number 82 (Friday, April 27, 2012)]
[Rules and Regulations]
[Pages 25236-25282]
[FR Doc No: 2012-9800]

Vol. 77

Friday,

No. 82

April 27, 2012

Part II

Environmental Protection Agency

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40 CFR Parts 9 and 721

Significant New Use Rules on Certain Chemical Substances; Final Rule

Federal Register / Vol. 77 , No. 82 / Friday, April 27, 2012 / Rules
and Regulations

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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Parts 9 and 721

[EPA-HQ-OPPT-2011-0577; FRL-9343-4]
RIN 2070-AB27

Significant New Use Rules on Certain Chemical Substances

AGENCY: Environmental Protection Agency (EPA).

ACTION: Direct final rule.

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SUMMARY: EPA is promulgating significant new use rules (SNURs) under
the Toxic Substances Control Act (TSCA) for 119 chemical substances
which were the subject of premanufacture notices (PMNs). Four of these
chemical substances are subject to TSCA consent orders issued by EPA.
This action requires persons who intend to manufacture, import, or
process any of these 119 chemical substances for an activity that is
designated as a significant new use by this rule to notify EPA at least
90 days before commencing that activity. The required notification will
provide EPA with the opportunity to evaluate the intended use and, if
necessary, to prohibit or limit that activity before it occurs.

DATES: This rule is effective on June 26, 2012. For purposes of
judicial review, this rule shall be promulgated at 1 p.m. (e.s.t.) on
May 11, 2012.
    Written adverse or critical comments, or notice of intent to submit
adverse or critical comments, on one or more of these SNURs must be
received on or before May 29, 2012 (see Unit VI. of the SUPPLEMENTARY
INFORMATION).
    For additional information on related reporting requirement dates,
see Units I.A., VI., and VII. of the SUPPLEMENTARY INFORMATION.

ADDRESSES: Submit your comments, identified by docket identification
(ID) number EPA-HQ-OPPT-2011-0577, by one of the following methods:
     Federal eRulemaking Portal: http://www.regulations.gov.
Follow the online instructions for submitting comments.
     Mail: Document Control Office (7407M), Office of Pollution
Prevention and Toxics (OPPT), Environmental Protection Agency, 1200
Pennsylvania Ave. NW., Washington, DC 20460-0001.
     Hand Delivery: OPPT Document Control Office (DCO), EPA
East, Rm. 6428, 1201 Constitution Ave. NW., Washington, DC. Attention:
Docket ID Number EPA-HQ-OPPT-2011-0577. The DCO is open from 8 a.m. to
4 p.m., Monday through Friday, excluding legal holidays. The telephone
number for the DCO is<PHONE_NUMBER>. Such deliveries are only accepted
during the DCO's normal hours of operation, and special arrangements
should be made for deliveries of boxed information.
    Instructions: Direct your comments to docket ID number EPA-HQ-OPPT-
2011-0577. EPA's policy is that all comments received will be included
in the docket without change and may be made available online at http://www.regulations.gov, including any personal information provided,
unless the comment includes information claimed to be Confidential
Business Information (CBI) or other information whose disclosure is
restricted by statute. Do not submit information that you consider to
be CBI or otherwise protected through regulations.gov or email. The
regulations.gov Web site is an ``anonymous access'' system, which means
EPA will not know your identity or contact information unless you
provide it in the body of your comment. If you send an email comment
directly to EPA without going through regulations.gov, your email
address will be automatically captured and included as part of the
comment that is placed in the docket and made available on the
Internet. If you submit an electronic comment, EPA recommends that you
include your name and other contact information in the body of your
comment and with any disk or CD-ROM you submit. If EPA cannot read your
comment due to technical difficulties and cannot contact you for
clarification, EPA may not be able to consider your comment. Electronic
files should avoid the use of special characters, any form of
encryption, and be free of any defects or viruses.
    Docket: All documents in the docket are listed in the docket index
available at http://www.regulations.gov. Although listed in the index,
some information is not publicly available, e.g., CBI or other
information whose disclosure is restricted by statute. Certain other
material, such as copyrighted material, will be publicly available only
in hard copy. Publicly available docket materials are available
electronically at http://www.regulations.gov, or, if only available in
hard copy, at the OPPT Docket. The OPPT Docket is located in the EPA
Docket Center (EPA/DC) at Rm. 3334, EPA West Bldg., 1301 Constitution
Ave. NW., Washington, DC. The EPA/DC Public Reading Room hours of
operation are 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding
legal holidays. The telephone number of the EPA/DC Public Reading Room
is<PHONE_NUMBER>, and the telephone number for the OPPT Docket is
(202) 566-0280. Docket visitors are required to show photographic
identification, pass through a metal detector, and sign the EPA visitor
log. All visitor bags are processed through an X-ray machine and
subject to search. Visitors will be provided an EPA/DC badge that must
be visible at all times in the building and returned upon departure.

FOR FURTHER INFORMATION CONTACT: For technical information contact:
Kenneth Moss, Chemical Control Division (7405M), Office of Pollution
Prevention and Toxics, Environmental Protection Agency, 1200
Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone number:
(202) 564-9232; email address<EMAIL_ADDRESS>    For general information contact: The TSCA-Hotline, ABVI-Goodwill,
422 South Clinton Ave., Rochester, NY 14620; telephone number: (202)
554-1404; email address<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this action apply to me?

    You may be potentially affected by this action if you manufacture,
import, process, or use the chemical substances contained in this rule.
Potentially affected entities may include, but are not limited to:
     Manufacturers, importers, or processors of one or more
subject chemical substances (NAICS codes 325 and 324110), e.g.,
chemical manufacturing and petroleum refineries.
    This listing is not intended to be exhaustive, but rather provides
a guide for readers regarding entities likely to be affected by this
action. Other types of entities not listed in this unit could also be
affected. The North American Industrial Classification System (NAICS)
codes have been provided to assist you and others in determining
whether this action might apply to certain entities. To determine
whether you or your business may be affected by this action, you should
carefully examine the applicability provisions in Sec.  721.5. If you
have any questions regarding the applicability of this action to a
particular entity, consult the technical person listed under FOR
FURTHER INFORMATION CONTACT.
    This action may also affect certain entities through pre-existing
import certification and export notification rules under TSCA. Chemical
importers are subject to the TSCA section 13 (15 U.S.C. 2612) import
certification requirements promulgated at 19 CFR 12.118 through 12.127;
see also 19 CFR 127.28. Chemical importers must certify that the
shipment of the chemical substance complies with all applicable rules
and orders under TSCA. Importers

of chemicals subject to these SNURs must certify their compliance with
the SNUR requirements. The EPA policy in support of import
certification appears at 40 CFR part 707, subpart B. In addition, any
persons who export or intend to export a chemical substance that is the
subject of this rule are subject to the export notification provisions
of TSCA section 12(b) (15 U.S.C. 2611(b)) (see Sec.  721.20), and must
comply with the export notification requirements in 40 CFR part 707,
subpart D.

B. What should I consider as I prepare my comments for EPA?

    1. Submitting CBI. Do not submit this information to EPA through
regulations.gov or email. Clearly mark the part or all of the
information that you claim to be CBI. For CBI information in a disk or
CD-ROM that you mail to EPA, mark the outside of the disk or CD-ROM as
CBI and then identify electronically within the disk or CD-ROM the
specific information that is claimed as CBI. In addition to one
complete version of the comment that includes information claimed as
CBI, a copy of the comment that does not contain the information
claimed as CBI must be submitted for inclusion in the public docket.
Information so marked will not be disclosed except in accordance with
procedures set forth in 40 CFR part 2.
    2. Tips for preparing your comments. When submitting comments,
remember to:
    i. Identify the document by docket ID number and other identifying
information (subject heading, Federal Register date and page number).
    ii. Follow directions. The Agency may ask you to respond to
specific questions or organize comments by referencing a Code of
Federal Regulations (CFR) part or section number.
    iii. Explain why you agree or disagree; suggest alternatives and
substitute language for your requested changes.
    iv. Describe any assumptions and provide any technical information
and/or data that you used.
    v. If you estimate potential costs or burdens, explain how you
arrived at your estimate in sufficient detail to allow for it to be
reproduced.
    vi. Provide specific examples to illustrate your concerns and
suggest alternatives.
    vii. Explain your views as clearly as possible, avoiding the use of
profanity or personal threats.
    viii. Make sure to submit your comments by the comment period
deadline identified.

II. Background

A. What action is the agency taking?

    EPA is promulgating these SNURs using direct final procedures.
These SNURs will require persons to notify EPA at least 90 days before
commencing the manufacture, import, or processing of a chemical
substance for any activity designated by these SNURs as a significant
new use. Receipt of such notices allows EPA to assess risks that may be
presented by the intended uses and, if appropriate, to regulate the
proposed use before it occurs. Additional rationale and background to
these rules are more fully set out in the preamble to EPA's first
direct final SNUR published in the Federal Register issue of April 24,
1990 (55 FR 17376) (April 24, 1990 SNUR). Consult that preamble for
further information on the objectives, rationale, and procedures for
SNURs and on the basis for significant new use designations, including
provisions for developing test data.

B. What is the agency's authority for taking this action?

    Section 5(a)(2) of TSCA (15 U.S.C. 2604(a)(2)) authorizes EPA to
determine that a use of a chemical substance is a ``significant new
use.'' EPA must make this determination by rule after considering all
relevant factors, including the four bulleted TSCA section 5(a)(2)
factors listed in Unit III. Once EPA determines that a use of a
chemical substance is a significant new use, TSCA section 5(a)(1)(B)
requires persons to submit a significant new use notice (SNUN) to EPA
at least 90 days before they manufacture, import, or process the
chemical substance for that use. Persons who must report are described
in Sec.  721.5.

C. Applicability of General Provisions

    General provisions for SNURs appear in 40 CFR part 721, subpart A.
These provisions describe persons subject to the rule, recordkeeping
requirements, exemptions to reporting requirements, and applicability
of the rule to uses occurring before the effective date of the rule.
Provisions relating to user fees appear at 40 CFR part 700. According
to Sec.  721.1(c), persons subject to these SNURs must comply with the
same notice requirements and EPA regulatory procedures as submitters of
PMNs under TSCA section 5(a)(1)(A). In particular, these requirements
include the information submission requirements of TSCA section 5(b)
and 5(d)(1), the exemptions authorized by TSCA section 5(h)(1),
5(h)(2), 5(h)(3), and 5(h)(5), and the regulations at 40 CFR part 720.
Once EPA receives a SNUN, EPA may take regulatory action under TSCA
section 5(e), 5(f), 6, or 7 to control the activities for which it has
received the SNUN. If EPA does not take action, EPA is required under
TSCA section 5(g) to explain in the Federal Register its reasons for
not taking action.

III. Significant New Use Determination

    Section 5(a)(2) of TSCA states that EPA's determination that a use
of a chemical substance is a significant new use must be made after
consideration of all relevant factors, including:
     The projected volume of manufacturing and processing of a
chemical substance.
     The extent to which a use changes the type or form of
exposure of human beings or the environment to a chemical substance.
     The extent to which a use increases the magnitude and
duration of exposure of human beings or the environment to a chemical
substance.
     The reasonably anticipated manner and methods of
manufacturing, processing, distribution in commerce, and disposal of a
chemical substance.
    In addition to these factors enumerated in TSCA section 5(a)(2),
the statute authorized EPA to consider any other relevant factors.
    To determine what would constitute a significant new use for the
119 chemical substances that are the subject of these SNURs, EPA
considered relevant information about the toxicity of the chemical
substances, likely human exposures and environmental releases
associated with possible uses, taking into consideration the four
bulleted TSCA section 5(a)(2) factors listed in this unit.

IV. Substances Subject to This Rule

    EPA is establishing significant new use and recordkeeping
requirements for 119 chemical substances in 40 CFR part 721, subpart E.
In this unit, EPA provides the following information for each chemical
substance:
     PMN number.
     Chemical name (generic name, if the specific name is
claimed as CBI).
     Chemical Abstracts Service (CAS) number (if assigned for
non-confidential chemical identities).
     Basis for the TSCA section 5(e) consent order or, for non-
section 5(e) SNURs, the basis for the SNUR (i.e., SNURs without TSCA
section 5(e) consent orders).
     Tests recommended by EPA to provide sufficient information
to evaluate the chemical substance (see Unit VIII. for more
information).
     CFR citation assigned in the regulatory text section of
this rule.

    The regulatory text section of this rule specifies the activities
designated as significant new uses. Certain new uses, including
production volume limits (i.e., limits on manufacture and importation
volume) and other uses designated in this rule, may be claimed as CBI.
Unit IX. discusses a procedure companies may use to ascertain whether a
proposed use constitutes a significant new use.
    This rule includes four PMN substances (P-10-470, P-10-471, P-10-
472, and P-11-217) for which EPA determined, pursuant to TSCA section
5(e), that uncontrolled manufacture, import, processing, distribution
in commerce, use, and disposal may present an unreasonable risk of
injury to human health and the environment. Accordingly, these
substances are subject to ``risk-based'' consent orders under TSCA
section 5(e)(1)(A)(ii)(I). Those consent orders require protective
measures to limit exposures or otherwise mitigate the potential
unreasonable risk. The so-called ``5(e) SNURs'' on these PMN substances
are promulgated pursuant to Sec.  721.160, and are based on and
consistent with the provisions in the underlying consent orders. The
5(e) SNURs designate as a ``significant new use'' the absence of the
protective measures required in the corresponding consent orders.
    This rule also includes SNURs on 115 PMN substances that are not
subject to consent orders under TSCA section 5(e). In these cases, for
a variety of reasons, EPA did not find that the use scenario described
in the PMN triggered the determinations set forth under TSCA section
5(e). However, EPA does believe that certain changes from the use
scenario described in the PMN could result in increased exposures,
thereby constituting a ``significant new use.'' These so-called ``non-
5(e) SNURs'' are promulgated pursuant to Sec.  721.170. EPA has
determined that every activity designated as a ``significant new use''
in all non-5(e) SNURs issued under Sec.  721.170 satisfies the two
requirements stipulated in Sec.  721.170(c)(2), i.e., these significant
new use activities, ``(i) are different from those described in the
premanufacture notice for the substance, including any amendments,
deletions, and additions of activities to the premanufacture notice,
and (ii) may be accompanied by changes in exposure or release levels
that are significant in relation to the health or environmental
concerns identified'' for the PMN substance.
    Where EPA determined that the PMN substance may present an
unreasonable risk of injury to human health via inhalation exposure,
the SNUR usually requires, among other things, that potentially exposed
employees wear specified respirators unless actual measurements of the
workplace air show that air-borne concentrations of the PMN substance
are below a New Chemical Exposure Limit (NCEL) that is established by
EPA to provide adequate protection to human health. In addition to the
actual NCEL concentration, the comprehensive NCELs provisions, which
are modeled after Occupational Safety and Health Administration (OSHA)
Permissible Exposure Limits (PELs) provisions, include requirements
addressing performance criteria for sampling and analytical methods,
periodic monitoring, respiratory protection, and recordkeeping.
However, no comparable NCEL provisions currently exist in 40 CFR part
721, subpart B, for SNURs. Therefore, for these cases, the individual
SNURs in 40 CFR part 721, subpart E, will state that persons subject to
the SNUR who wish to pursue NCELs as an alternative to the Sec.  721.63
respirator requirements may request to do so under Sec.  721.30.

PMN Numbers P-00-2, P-00-5, and P-00-6

    Chemical names: Polymeric MDI based polyurethanes (generic).
    CAS numbers: Not available.
    Basis for action: The PMNs state that the generic (non-
confidential) use of the substances will be as internal mold release.
Based on ecological structure-activity relationship (EcoSAR) analysis
of test data on analogous nonionic surfactants, EPA predicts toxicity
to aquatic organisms may occur at concentrations that exceed 1 part per
billion (ppb) of the PMN substances in surface waters. As described in
the PMNs, the substances are not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substances may present an unreasonable risk. EPA has
determined, however, that any use of the substances resulting in
surface water concentrations exceeding 1 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substances meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10299.

PMN Number P-00-85

    Chemical name: Benzeneacetic acid, .alpha.-chloro-.alpha.-phenyl-,
ethyl ester.
    CAS number: 52460-86-3.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a reaction aid in polymer
synthesis. Based on EcoSAR analysis of test data on analogous benzyl
halides, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 2 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 2 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10300.

PMN Number P-00-317

    Chemical name: Reaction products of fatty alcohols,
(aminoethylaminopropyl)dialkoxymethylsilane, glycidol, and hydroxy-
terminated polydimethylsiloxane (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
a silicone textile treatment. Based on EcoSAR analysis of test data on
analogous polycationic polymers, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 40 ppb of the PMN
substance in surface waters. As described in the PMN, releases of the
substance are not expected to result in surface water concentrations
that exceed 40 ppb. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding

40 ppb may cause significant adverse environmental effects. Based on
this information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10301.

PMN Number P-00-442

    Chemical name: Zinc ammonium phosphate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a fertilizer. Based on
EcoSAR analysis of test data on analogous zinc salts and inorganic
phosphates, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 2 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 2 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10302.

PMN Number P-00-833

    Chemical name: Polyether modified polysiloxane, acrylated
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a non-dispersive
additive. Based on test data on the PMN substance, and EcoSAR analysis
of test data on analogous acrylates, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 4 ppb of the PMN
substance in surface waters. As described in the PMN, releases of the
substance are not expected to result in surface water concentrations
that exceed 4 ppb. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 4 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170 (b)(4)(i) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help to characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10303.

PMN Number P-00-1099

    Chemical name: Functionalized polymethine (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an infra red absorber.
Based on EcoSAR analysis of test data on analogous cationic dyes, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 1 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any use of the substance resulting in surface
water concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help to characterize the environmental effects of the PMN
substance.
    CFR citation: 40 CFR 721.10304.

PMN Number P-00-1108

    Chemical name: Modified cyclohexane esters (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a plasticizer. Based on
EcoSAR analysis of test data on analogous epoxides, EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed 1
ppb of the PMN substance in surface waters. As described in the PMN,
the substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10305.

PMN Number P-01-114

    Chemical name: Substituted phenylepoxide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a destructive use (i.e.,
destroyed during process of manufacturing) electric devices. Based on
test data on the PMN substance and EcoSAR analysis of test data on
analogous epoxides, EPA predicts toxicity to aquatic organisms may
occur at concentrations that exceed 6 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 6 ppb may
cause significant adverse environmental effects. Based on this
information the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(i) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help to characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10306.

PMN Number P-01-343

    Chemical name: Acrylate resin (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an adhesive coating.
Based on EcoSAR analysis of test data on analogous acrylates, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 2 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any use of the substance resulting in surface
water concentrations exceeding 2 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10307.

PMN Numbers P-01-384, P-01-385, P-01-386, P-01-387, and P-01-388

    Chemical names: (P-01-384) Ethoxylated, propoxylated diamine diaryl
substituted phenylmethane ester with alkenylsuccinate,
dialkylethanolamine salt (generic); (P-01-385) Ethoxylated,
propoxylated diamine diaryl substituted phenylmethane ester with
alkenylsuccinate (generic); (P-01-386) Ethoxylated, propoxylated
diamine diaryl substituted phenylmethane ester with alkenylsuccinate,
ammonium salt (generic); (P-01-387) Ethoxylated, propoxylated diamine
diaryl substituted phenylmethane ester with alkenylsuccinate, sodium
salt (generic); and (P-01-388) Ethoxylated, propoxylated diamine diaryl
substituted phenylmethane ester with alkenylsuccinate, ethanolamine
salt (generic).
    CAS numbers: Not available.
    Basis for action: The consolidated PMN states that the generic
(non-confidential) use of the substances will be as colorants for
aqueous ink applications. Based on EcoSAR analysis of test data on
analogous amphoteric dyes, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 70 ppb of the PMN substances in
surface waters. As described in the PMNs, the substances are not
released to surface waters. Therefore, EPA has not determined that the
proposed manufacturing, processing, or use of the substances may
present an unreasonable risk. EPA has determined, however, that any use
of the substances resulting in surface water concentrations exceeding
70 ppb may cause significant adverse environmental effects. Based on
this information, the PMN substances meet the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help to characterize the environmental effects of the PMN substances.
    CFR citations: 40 CFR 721.10308 (P-01-384); 40 CFR 721.10309 (P-01-
385); 40 CFR 721.10310 (P-01-386); 40 CFR 721.10311 (P-01-387); and 40
CFR 721.10312 (P-01-388).

PMN Number P-02-249

    Chemical name: Fatty acids, C16-18 and C18-unsatd., Me esters,
epoxidized.
    CAS number: 158318-67-3.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a raw material for
production of polyols. Based on EcoSAR analysis of test data on
analogous polyepoxides, EPA predicts toxicity to aquatic organisms may
occur at concentrations that exceed 8 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 8 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help to characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10313.

PMN Numbers P-02-778, P-02-779, and P-02-780

    Chemical names: Dialkyl dithiocarbamate esters (generic).
    CAS numbers: Not available.
    Basis for action: The PMNs state that the generic (non-
confidential) use of the substances will be used as petroleum
additives. EPA identified environmental concerns because the PMN
substances may be persistent, bio-accumulative, and toxic (PBT)
chemicals, based on physical/chemical properties of the PMN substances,
as described in the New Chemicals Program's PBT category (64 FR 60194,
November 4, 1999) (FRL-6097-7). EPA estimates that the PMN substances
will persist in the environment for more than two months and estimates
a bioaccumulation factor of greater than or equal to 1,000. Also, based
on EcoSAR analysis of test data on analogous esters, EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed 1
ppb of the PMN substances in surface waters. As described in the PMNs,
the substances are not released to surface waters. Therefore, EPA has
not determined that the proposed manufacturing, processing, or use of
the substances may present an unreasonable risk. EPA has determined,
however, that any purposeful or predictable release containing the PMN
substances into the waters of the United States may cause significant
adverse environmental effects since the PMN substances have been
characterized by EPA as PBTs. Based on this information, the PMN
substances meet the concern criteria at Sec.  721.170(b)(4)(ii) and
(b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substances.
    CFR citation: 40 CFR 721.10314.

PMN Number P-02-833

    Chemical name: 1,5-Dioxa-9-azaspiro[5.5]undecane, 3,3,8,8,10,10-
hexamethyl-9-[1-[4-(2-oxiranylmethoxy)phenyl]ethoxy]-.
    CAS number: 434898-80-3.
    Basis for action: The PMN states that the substance will be used as
a polymerization initiator for thermoplastics and elastomers. EPA
identified environmental concerns because the substance may be a PBT
chemical, based on physical/chemical properties of the PMN substance,
as described in the New Chemicals

Program's PBT category. EPA estimates that the PMN substance will
persist in the environment more than two months and estimates a
bioaccumulation factor of greater than or equal to 1,000. Also, based
on EcoSAR analysis of test data on analogous aliphatic amines, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 1ppb of the PMN substance in surface waters. As described in the
PMN, the substance is not released to surface waters. Therefore, EPA
has not determined that the proposed manufacturing, processing, or use
of the substance may present an unreasonable risk. EPA has determined,
however, that any purposeful or predictable release containing the PMN
substance into the waters of the United States may cause significant
adverse environmental effects since the PMN substance has been
characterized by EPA as a PBT. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170 (b)(4)(ii) and
(b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help to characterize the PBT attributes of the PMN substance.
    CFR citation: 40 CFR 721.10315.

PMN Number P-02-872

    Chemical name: Dicyclopentadiene polymer with maleic anhydride and
alkyl alcohols (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an open-dispersive use in
molding operations. Based on EcoSAR analysis of test data on analogous
acrylates, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 3 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 3 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
determination of the partition coefficient (n-octanol/water) by shake
flask method (OPPTS Test Guideline 830.7550), generator column method
(OPPTS Test Guideline 830.7560), or estimation by liquid chromatography
(OPPTS Test Guideline 830.7570); a fish acute toxicity test, freshwater
and marine (OPPTS Test Guideline 850.1075); an aquatic invertebrate
acute toxicity test, freshwater daphnids (OPPTS Test Guideline
850.1010); and an algal toxicity test, tiers I and II (OPPTS Test
Guideline 850.5400) would help to characterize the environmental
effects of the PMN substance.
    CFR citation: 40 CFR 721.10316.

PMN Number P-02-1040

    Chemical name: Alkyl phosphate derivative (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a processing aid. Based
on EcoSAR analysis of test data on analogous soluble complexes of zinc,
such as zinc-phosphate salts, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 10 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any use
of the substance resulting in surface water concentrations exceeding 10
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10317.

PMN Numbers P-02-1078 and P-02-1080

    Chemical names: Mannich bases (generic).
    CAS numbers: Not available.
    Basis for action: The PMNs state that the substances will be used
as curatives for epoxy resin to improve chemical resistance. Based on
EcoSAR analysis of test data on analogous polycationic polymers, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 40 ppb of the PMN substances in surface waters. As described in
the PMNs, the substances are not released to surface waters. Therefore,
EPA had not determined that the proposed manufacturing, processing, or
use of the substances may present an unreasonable risk. EPA has
determined, however, that any use of the substances resulting in
surface water concentrations exceeding 40 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substances meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
porous pot test (OPPTS Test Guideline 835.3220); a fish acute toxicity
test, freshwater and marine (OPPTS Test Guideline 850.1075); a fish
acute toxicity mitigated by humic acid (OPPTS Test Guideline 850.1085);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help to characterize the
environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10318.

PMN Number P-03-42

    Chemical name: Alkylamides, ethoxylated (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a surfactant. Based on
EcoSAR analysis of test data on analogous nonionic surfactants, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 4 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any use of the substance resulting in surface
water concentrations exceeding 4 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10319.

PMN Number P-03-186

    Chemical name: Fatty acid amide (generic).

    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a lubricant additive.
Based on EcoSAR analysis of test data on analogous nonionic surfactants
and neutral organic chemicals, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 8 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any use
of the substance resulting in surface water concentrations exceeding 8
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10320.

PMN Number P-03-194

    Chemical name: Bis[phenyl, 2H-1,3-benzoxazine]derivative (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
a resin for electronic laminates, adhesive resins, encapsulant resins,
and composite resins. EPA has identified environmental concerns because
the substance may be a PBT chemical, based on physical/chemical
properties of the PMN substance, as described in the New Chemicals
Program's PBT category. Also, based on EcoSAR analysis of test data on
analogous neutral organic chemicals, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 1 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any
purposeful or predictable release containing the substance into the
waters of the United States may cause significant adverse environmental
effects since the PMN substance has been characterized by EPA as a PBT.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii) and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance. In
addition, EPA has determined that the results of a fish early-life
stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic
toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10321.

PMN Number P-03-196

    Chemical name: Metallic diol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an additive for coatings,
inks, adhesives, and composites. Based on EcoSAR analysis of test data
on analogous zinc compounds, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 6 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not expected
to be released to surface waters in concentrations that exceed 6 ppb.
Therefore, EPA has not determined that the proposed manufacturing,
processing, or use of the substance may present an unreasonable risk.
EPA has determined, however, that any use of the substance resulting in
releases to surface waters exceeding 6 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10322.

PMN Number P-03-248

    Chemical name: Glycerol fatty acid ester (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a plastic film additive.
Based on EcoSAR analysis of test data on analogous nonionic
surfactants, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 6 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, and use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 6 ppb may
cause significant adverse environmental effects. Based on this
information the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early life stage toxicity study (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity study (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help to characterize the environmental effects of the PMN
substance.
    CFR citation: 40 CFR 721.10323.

PMN Number P-03-362

    Chemical name: Thionocarbamate derivative (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a sulfide mineral
processing reagent. Based on test data on the PMN substance, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 50 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not expected to be released to surface waters
in concentrations that exceed 50 ppb. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 50 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(i).
    Recommended testing: EPA has determined that the results of a
porous pot test (OPPTS Test Guideline 835.3220) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10324.

PMN Number P-03-442

    Chemical name: Cyclosilazanes, di-Me, Me hydrogen, polymers with
di-Me,

Me hydrogen silazanes, reaction products with 3-(triethoxysilyl)-1-
propanamine.
    CAS number: 475645-84-2.
    Basis for action: The PMN states that the substance will be used as
a coating material. Based on EcoSAR analysis of test data on analogous
polycationic polymers, EPA predicts toxicity to aquatic organisms may
occur at concentrations that exceed 10 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 10 ppb
may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075), an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010), and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10325.

PMN Number P-03-458

    Chemical name: 2-Propenoic acid, 2-methyl-, methyl ester, polymer
with butyl 2-propenoate, ethyl 2-propenoate, zinc 2-methyl-2-propenoate
(1:2) and zinc 2-propenoate (1:2), 2,2'-(1,2-diazenediyl)bis[2-
methylbutanenitrile]- and 2,2'-(1,2-diazenediyl)bis[2-
methylpropanenitrile]-initiated.
    CAS number: 460739-39-3.
    Basis for action: The PMN states that the substance will be used as
a binder polymer in paints. Based on EcoSAR analysis of test data on
analogous soluble complexes of zinc, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 10 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface water. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any use
of the substance resulting in surface water concentrations exceeding 10
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10326.

PMN Numbers P-03-529, P-03-530, and P-03-531

    Chemical names: (P-03-529) Salt of mixed fatty amidoamines and
polyethylenepolyamines (generic); (P-03-530) Salt of
polyalkylenepolyamine derivative (generic); and (P-03-531) Salt of
mixed fatty amidoamines (generic).
    CAS numbers: Not available.
    Basis for action: The consolidated PMN states that the generic
(non-confidential) use of the substances will be as processing aids.
Based on EcoSAR analysis of test data on analogous cationic
surfactants, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 10 ppb of the PMN substances in surface
waters. As described in the PMNs, the substances are not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substances may present an
unreasonable risk. EPA has determined, however, that any use of the
substances resulting in surface water concentrations exceeding 10 ppb
may cause significant adverse environmental effects. Based on this
information, the PMN substances meet the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
porous pot test (OPPTS Test Guideline 835.3220) would help to
characterize the environmental fate of the PMN substances.
    CFR citations: 40 CFR 721.10327 (P-03-529); 40 CFR 721.10328 (P-03-
530); and 40 CFR 721.10329 (P-03-531).

PMN Number P-03-722

    Chemical name: Pyrazolone derivative (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a dye for use in thermal
transfer printing systems. EPA has identified environmental concerns
because the substance may be a PBT chemical, based on physical/chemical
properties of the PMN substance, as described in the New Chemicals
Program's PBT category. Also, based on test data on the PMN substance
and EcoSAR analysis of test data on analogous hydrazines, EPA predicts
toxicity to aquatic organisms at surface water concentrations that
exceed 1 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any use of the substance resulting in release
to surface waters may cause significant adverse environmental effects
since the PMN substance has been characterized by EPA as a PBT. Based
on this information, the PMN substance meets the concern criteria at
Sec.  721.170 (b)(4)(i), (b)(4)(ii), and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance. In
addition, EPA has determined that the results of a fish early-life
stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic
toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10330.

PMN Number P-03-767

    Chemical name: Aromatic isocyanate methacrylate blocked (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a component in composite
formulations. Based on EcoSAR analysis of test data on analogous
methacrylates and esters, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 1 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 1 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic

toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10331.

PMN Number P-03-824

    Chemical name: Lithium metal phosphate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an electrode material.
Based on EcoSAR analysis of test data on analogous inorganic
phosphates, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 4 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 4 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10332.

PMN Number P-03-840

    Chemical name: Substituted benzamine thio-ether (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a raw material. Based on
EcoSAR analysis of test data on analogous anilines, EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed 1
ppb of the PMN substance in surface waters. As described in the PMN,
the substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the PMN substance resulting in surface water
concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10333.

PMN Number P-03-861

    Chemical name: Ethanol, 2,2'-[(3-[(2-
ethylhexyl)oxy]pentyl]imino]bis-.
    CAS number: 284477-82-3.
    Basis for action: The PMN states that the substance will be used as
an intermediate, emulsifier for industrial textile softening, and an
industrial dye additive. Based on EcoSAR analysis of test data on
analogous aliphatic amines, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 20 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 20 ppb
may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help to characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10334.

PMN Number P-03-862

    Chemical name: 1-Pentanamine, 3-[(2-ethylhexyl)oxy]-.
    CAS number: 174615-16-8.
    Basis for action: The PMN states that the substance will be used as
a surfactant intermediate. Based on EcoSAR analysis of test data on
analogous aliphatic amines, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 7 ppb of the PMN substance in
surface waters. As described in the PMN, releases of the substance are
not expected to result in surface water concentrations that exceed 7
ppb. Therefore, EPA has not determined that the proposed manufacturing,
processing, or use of the substance may present an unreasonable risk.
EPA has determined, however, that any use of the substance resulting in
surface water concentrations exceeding 7 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help to characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10335.

PMN Number P-04-1

    Chemical name: Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxo-2-propen-1-
yl)-.omega.-([1,1'-biphenyl]-2-yloxy)-.
    CAS number: 72009-86-0.
    Basis for action: The PMN states that the substance will be used as
an ultra violet (UV)-curable additive for optical lens. Based on EcoSAR
analysis of test data on analogous acrylates, EPA predicts toxicity to
aquatic organisms may occur at concentrations that exceed 3 ppb of the
PMN substance in surface waters. As described in the PMN, the substance
is not released to surface waters. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 3 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would

help to characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10336.

PMN Number P-04-6

    Chemical name: Copper, iodotris(triphenylphosphine)-, (T-4)-.
    CAS number: 15709-82-7.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an additive. EPA has
identified environmental concerns because the substance may be a PBT
chemical, based on physical/chemical properties of the PMN substance,
as described in the New Chemicals Program's PBT category. EPA estimates
that the PMN substance will persist in the environment for more than
six months and estimates a bioaccumulation factor of greater than or
equal to 1,000. In addition, based on test data on the PMN substance
and EcoSAR analysis of analogous neutral organics, EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed
60 ppb of the PMN substance in surface water. As described in the PMN,
the substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
PMN substance may present an unreasonable risk. EPA has determined,
however, that any purposeful or predictable release containing the PMN
substance into the waters of the United States may cause serious
significant adverse environmental effects since the PMN substance has
been characterized by EPA as a PBT. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170 (b)(4)(i),
(b)(4)(ii), and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance.
    CFR citation: 40 CFR 721.10337.

PMN Number P-04-53

    Chemical name: 2-Propenoic acid, 1,1'-(1,9-nonanediyl) ester.
    CAS number: 107481-28-7.
    Basis for action: The PMN states that the substance will be used as
a UV-curable monomer for optical lens. Based on EcoSAR analysis of test
data on analogous acrylates, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 2 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 2 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results a fish
acute toxicity study (OPPTS Test Guideline 850.1075); a daphnid acute
toxicity study (OPPTS Test Guideline 850.1010); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10338.

PMN Number P-04-113

    Chemical name: Adipic acid, substituted propane, alkyldiol,
acrylate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an open non-dispersive
acrylate resin. Based on EcoSAR analysis of test data on analogous
acrylates and esters, EPA predicts toxicity to aquatic organisms may
occur at concentrations that exceed 1 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 1 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity, tiers
I and II (OPPTS Test Guideline 850.5400) would help to characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10339.

PMN Number P-04-146

    Chemical name: Potassium zinc fluoride (KZnF3).
    CAS number: 13827-02-6.
    Basis for action: The PMN states that the substance will be used as
a flux for brazing aluminum. Based on EcoSAR analysis of test data on
analogous zinc compounds, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 2 ppb of the PMN substance in
surface waters. As described in the PMN, the substance is not released
to surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 2 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that results of a porous
pot test (OPPTS Test Guideline 835.3220); a fish acute toxicity test,
freshwater and marine (OPPTS Test Guideline 850.1075); an aquatic
invertebrate acute toxicity test, freshwater daphnids (OPPTS Test
Guideline 850.1010); and an algal toxicity test, tiers I and II (OPPTS
Test Guideline 850.5400) would help to characterize the environmental
effects of the PMN substance.
    CFR citation: 40 CFR 721.10340.

PMN Number P-04-338

    Chemical name: Amino alkyl organoborane (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a polymerization
catalyst/initiator for thermosetting acrylic adhesive. Based on EcoSAR
analysis of test data on analogous aminoborane, EPA predicts toxicity
to aquatic organisms may occur at concentrations that exceed 7 ppb of
the PMN substance in surface waters. As described in the PMN, the
substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 7 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help to
characterize the environmental effects of the PMN substance.

    CFR citation: 40 CFR 721.10341.

PMN Number P-04-516

    Chemical name: Quaternary ammonium compounds, fatty alkyl dialkyl
hydroxide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a fuel additive. Based on
EcoSAR analysis of test data on analogous cationic surfactants, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 4 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any use of the substance resulting in surface
water concentrations exceeding 4 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); a fish acute toxicity mitigated by humic acid (OPPTS Test
Guideline 850.1085); an aquatic invertebrate acute toxicity test,
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal
toxicity test, tiers I and II (OPPTS Test Guideline 850.5400) would
help to characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10342.

PMN Number P-04-563

    Chemical name: Alkylated aryloxyaniline thiourea (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
a pesticide intermediate. EPA identified environmental concerns because
the PMN substance may be a PBTchemical based on physical/chemical
properties of the PMN substance as described in the New Chemicals
Program's PBT category. EPA estimates that the PMN substance will
persist in the environment for more than two months and estimates a
bioaccumulation factor of greater than or equal to 5,000. Also, based
on EcoSAR analysis of test data on analogous neutral organics and
isocyanates, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 2 ppb of the substance in surface waters.
According to the scenario described in the PMN, the substance is not
released to surface waters. Therefore, EPA has not determined that the
proposed manufacturing, processing, or use of the substance may present
an unreasonable risk. EPA has determined, however, that any purposeful
or predictable release containing the substance into the waters of the
United States may cause significant environmental effects since the PMN
substance has been characterized by EPA as a PBT. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170 (b)(4)(ii) and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance.
    CFR citation: 40 CFR 721.10343.

PMN Number P-04-810

    Chemical name: Alkylated aromatic isothiocyanate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
an insecticide intermediate. EPA identified environmental concerns
because the PMN substance may be a PBT chemical based on physical/
chemical properties of the PMN substance, as described in the New
Chemicals Program's PBT category. EPA estimates that the PMN substance
will persist in the environment for more than two months and estimates
a bioaccumulation factor of greater than or equal to 5,000. Also, based
on EcoSAR analysis of test data on analogous neutral organics and
isocyanates, EPA predicts toxicity to aquatic organisms at
concentrations that exceed 1,000 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any purposeful or
predictable release containing the substance into the waters of the
United States may cause significant environmental effects since the PMN
substance has been characterized by EPA as a PBT. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170 (b)(4)(ii) and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance.
    CFR citation: 40 CFR 721.10344.

PMN Number P-05-110

    Chemical name: 1,2-Benzenedicarboxylic acid, 1,2-
bis(methylcyclohexyl) ester.
    CAS number: 27987-25-3.
    Basis for action: The PMN states that the substance will be used as
a plastic softener. Based on EcoSAR analysis of test data on analogous
esters, EPA predicts that toxicity to aquatic organisms may occur at
concentrations that exceed 1 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 1 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10345.

PMN Number P-05-599

    Chemical name: 3H-Indolium, 2-[2-[2-chloro-3-[2-(1,3-dihydro-3,3-
dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-
yl]ethenyl]-3,3-dimethyl-1-propyl-, iodide (1:1).
    CAS number: 207399-07-3.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an additive for coating
compositions. Based on EcoSAR analysis of test data on analogous
cationic dyes, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 1 ppb of the PMN substance in surface
waters. As described in the PMN, releases of the substance are not
expected to result in surface water concentrations that exceed 1 ppb.
Therefore, EPA has not determined that the proposed manufacturing,
processing, or use of the substance will present an unreasonable risk.
EPA has determined; however, that any use of the substance resulting in
surface water concentrations exceeding 1 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).

    Recommended testing: EPA had determined that the results of a Zahn-
Wellens/EMPA test (OPPTS Test Guideline 835.3200); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075),
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010), and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10346.

PMN Number P-06-268

    Chemical name: Bicyclo[2.2.1]heptanedimethanamine, N,N'-bis(1,2-
dimethylpropylidene)-.
    CAS number: 664980-30-7.
    Basis for action: The PMN states that the substance will be used as
a curing agent for epoxides and urethanes. Based on EcoSAR analysis of
test data on analogous aliphatic amines, EPA predicts toxicity to
aquatic organisms may occur at concentrations that exceed 10 ppb of the
PMN substance in surface waters. As described in the PMN, the substance
is not released to surface waters. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 10 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10347.

PMN Numbers P-06-623 and P-06-624

    Chemical names: Aspartic acid, N,N'-(iminodi-alkanediyl)bis,
tetraalkane esters (generic).
    CAS numbers: Not available.
    Basis for action: The consolidated PMN states that the generic
(non-confidential) use of the substances will be as components of
industrial coatings. Based on EcoSAR analysis of test data on analogous
aliphatic amines and esters, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 3 ppb of the PMN substances in
surface waters. As described in the PMN, the substances are not
released to surface waters. Therefore, EPA has not determined that the
proposed manufacturing, processing, or use of the substances may
present an unreasonable risk. EPA has determined, however, that any use
of the substances resulting in surface water concentrations exceeding 3
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substances meet the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradation test (OPPTS Test Guideline 835.3100); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075),
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010), and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help characterize the
environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10348.

PMN Number P-06-731

    Chemical name: 1,4-Benzenediamine, N'-(alkyl)-N-[4-
[(alkyl)amino]phenyl]-N-phenyl- (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be used as an open, non-
dispersive resin. Based on EcoSAR analysis of test data on analogous
cationic dyes, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 1 ppb of the PMN substance in surface
waters. As described in the PMN, the substance is not released to
surface waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, and use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 1 ppb may
cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help to characterize the environmental effects of the PMN
substance.
    CFR citation: 40 CFR 721.10349.

PMN Number P-06-742

    Chemical name: Amines, C11-14-branched and linear alkyl.
    CAS number: 863766-30-7.
    Basis for action: The PMN states that the substance will be used as
a raw material. EPA identified environmental concerns because the PMN
substance may be a PBT chemical based on physical/chemical properties
of the PMN substance as described in the New Chemicals Program's PBT
category. EPA estimates that the PMN substance will persist in the
environment for more than two months and estimates a bioaccumulation
factor of greater than or equal to 1,000. Also, based on EcoSAR
analysis of test data on analogous aliphatic amines, EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed 1
ppb of the PMN substance in surface waters. As described in the PMN,
the substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any purposeful or predictable release containing the PMN
substance into the waters of the United States may cause significant
adverse environmental effects since the PMN substance has been
characterized by EPA has a PBT. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170 (b)(4)(ii) and
(b)(4)(iii).
    Recommended testing: EPA has determined that the results of the
tiered testing described in the New Chemicals Program's PBT category
would help characterize the PBT attributes of the PMN substance.
    CFR citation: 40 CFR 721.10350.

PMN Number P-07-351

    Chemical name: Carbomonocycle, bis[(4-methylphenoxy)methyl]-
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a component of a
manufactured consumer article. Based on EcoSAR analysis of test data on
analogous neutral organic chemicals, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 1 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
manufacturing, processing, and use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 1 ppb may
cause significant adverse environmental effects. Based on this
information the PMN substance meets

the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10351.

PMN Number P-08-93

    Chemical name: Dimethyl terephthalate, polymer with alkyl diol and
substituted benzoates (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a binder in foundry
applications. Based on EcoSAR analysis of test data on analogous
esters, EPA predicts toxicity to aquatic organisms may occur at
concentrations that exceed 60 ppb of the PMN substance in surface
waters. As described in the PMN, releases of the PMN substance are not
expected to result in surface water concentrations that exceed 60 ppb.
Therefore, EPA has not determined that the proposed manufacturing,
processing, or use of the substance may present an unreasonable risk.
EPA has determined, however, that any use of the substance resulting in
surface water concentrations exceeding 60 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
porous pot test (Organisation for Economic Co-operation and Development
(OECD) Test Guideline 303A); an aquatic invertebrate acute toxicity
test, freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal
toxicity, tiers I and II (OPPTS Test Guideline 850.5400) would help
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10352.

PMN Number P-08-510

    Chemical name: Organosulfide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a co-stabilizer for
plastics. Based on EcoSAR analysis of test data on analogous esters,
EPA predicts toxicity to aquatic organisms may occur at concentrations
that exceed 1 ppb in surface waters. As described in the PMN, releases
of the PMN substance are not expected to result in surface water
concentrations that exceed 1 ppb. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 1 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early life-stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10353.

PMN Number P-08-623

    Chemical name: 1,1'-Biphenyl, 3,3',4,4'-tetramethyl-.
    CAS number: 4920-95-0.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a raw material for
production of biphenyl dianhydride. Based on EcoSAR analysis of test
data on analogous neutral organic chemicals, EPA predicts toxicity to
aquatic organisms may occur at concentrations that exceed 1 ppb of the
PMN substance in surface waters. As described in the PMN, releases of
the PMN substance are not expected to result in surface water
concentrations that exceed 1 ppb. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 1 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10354.

PMN Number P-08-722

    Chemical name: Poly(oxy-1,2-ethanediyl), .alpha.-(1-
oxododecyl)-.omega.-[3-triethoxysilyl)propoxy]-.
    CAS number: 1041420-54-5.
    Basis for action: The PMN states that the substance will be used as
a pigment treatment and surface treatment agent. Based on EcoSAR
analysis of test data on analogous esters, EPA predicts toxicity to
aquatic organisms may occur at concentrations that exceed 1 ppb of the
PMN substance in surface waters. As described in the PMN, the substance
will not be released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
hydrolysis test (OPPTS Test Guideline 835.2120); a fish early-life
stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic
toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10355.

PMN Number P-09-98

    Chemical name: Zinc, bis[3-(acetyl-.kappa.O)-6-methyl-2H-pyran-
2,4(3H)-dionato-.kappa.O4]diaqua-.
    CAS number: 171884-15-4.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a polymer additive. Based
on EcoSAR analysis of test data on analogous zinc compounds and allyl/
vinyl esters, with molecular weight adjustments, EPA predicts toxicity
to aquatic organisms may occur at concentrations that exceed 4 ppb of
the PMN substance in surface waters. As described in the PMN, the
substance is not released to surface waters. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 4 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an

aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10356.

PMN Number P-09-382

    Chemical name: Iron, citrate phosphate potassium complexes.
    CAS number: 120579-31-9.
    Basis for action: The PMN states that the substance will be used as
a nutrient for agriculture, and as an intermediate used to manufacture
agricultural soil amendments. Based on EcoSAR analysis of test data on
analogous inorganic phosphates, EPA predicts toxicity to aquatic
organisms may occur if releases of the PMN substance to surface water,
from uses other than as described in the PMN, exceed releases from the
use described in the PMN. For the described use in the PMN, where the
substance will only be transported in drums with a maximum capacity of
20 gallons, or in bottom-loading totes, significant environmental
releases are not expected. Therefore, EPA has not determined that the
proposed manufacturing, processing, or use of the substance may present
an unreasonable risk. EPA has determined, however, that use of the
substance other than as described in the PMN could result in exposures
which may cause significant adverse environmental effects. Based on
this information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10357.

PMN Number P-09-546

    Chemical name: Formaldehyde reaction products with aryl amine
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an intermediate. Based on
EcoSAR analysis of test data on analogous anilines, EPA predicts
toxicity to aquatic organisms may occur if releases of the PMN
substance to surface water, from uses other than as described in the
PMN, exceed the releases expected from the use described in the PMN.
For the intermediate use described in the PMN, significant
environmental releases are not expected. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use other than as an intermediate that has been
manufactured using the process described in the premanufacture notice
may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10358.

PMN Number P-09-613

    Chemical name: Cardanol-based alkyl phosphate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
a site-limited polymer modifier for non-consumer products. Based on
EcoSAR analysis of test data on analogous anionic surfactants and
organic phosphates, EPA predicts toxicity to aquatic organisms may
occur at concentrations that exceed 18 ppb of the PMN substance in
surface waters. For the use described in the PMN, general population
exposure is limited and the substance is not released to surface
waters. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 18 ppb
may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii). EPA has also determined, however, in accordance with
TSCA section 5(a)(2)(A) and 5(a)(2)(C) and with Sec.  721.170(a), that
uses other than as described in the PMN may result in significant human
exposures.
    Recommended testing: EPA has determined that the results of an
acute oral toxicity study (OPPTS Test Guideline 870.1100) or an acute
oral toxicity up-and-down procedure (OECD Test Guideline 425); a
bacterial reverse mutation test (OPPTS Test Guideline 870.5100); a
mammalian erythrocyte micronucleus test via the intraperitoneal route
(OPPTS Test Guideline 870.5395); a repeated dose 28-day oral toxicity
test in rodents (OPPTS Test Guideline 870.3050 or OECD Test Guideline
407) with a neurotoxicity functional observational screening battery
(OPPTS Test Guideline 870.6200) for all test doses; a fish early-life
stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic
toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity
test, tiers I and II (OPPTS Test Guideline 850.5400) would help
characterize the human health and environmental effects of the PMN
substance.
    CFR citation: 40 CFR 721.10359.

PMN Number P-09-628

    Chemical name: 1-Substituted propane, 3-(triethoxysilyl)-, reaction
products with polyethylene glycol mono-(branched tridecyl) ether
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a cross-linking, coupling
agent. Based on test data on the PMN substance, EPA predicts toxicity
to aquatic organisms may occur at concentrations that exceed 4 ppb of
the PMN substance in surface waters. As described in the PMN, the
substance will not be released to surface waters. Therefore, EPA has
not determined that the proposed manufacturing, processing, or use of
the substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 4 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(i).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10360.

PMN Number P-10-15

    Chemical name: Anthraquinonedicarboximide, diamino-N-alkyl-
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a fuel additive.

Based on EcoSAR analysis of test data on analogous imides and anilines,
EPA predicts toxicity to aquatic organisms may occur at concentrations
that exceed 1 ppb of the PMN substance in surface waters. As described
in the PMN, releases of the PMN substance are not expected to result in
surface water concentrations that exceed 1 ppb. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) with
sheepshead minnows; a mysid chronic toxicity test (OPPTS Test Guideline
850.1350); and an algal toxicity test, tiers I and II (OPPTS Test
Guideline 850.5400) with diatom Skeletonema costatum would help
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10361.

PMN Number P-10-44

    Chemical name: Oils, callitropsis nootkatensis.
    CAS number: 1069136-34-0.
    Basis for action: The PMN states that the substance will be used as
a fragrance ingredient. Based on EcoSAR analysis of test data on
analogous neutral organic compounds (hydrocarbons), EPA predicts
toxicity to aquatic organisms may occur at concentrations that exceed 1
ppb of the PMN substance in surface waters. As described in the PMN,
releases of the PMN substance are not expected to result in surface
water concentrations that exceed 1 ppb. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 1 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10362.

PMN Number P-10-47

    Chemical name: Alkenoic acid, 2-methyl-, 2-oxiranylmethyl ester,
reaction products with 4,4'-methylenebis (cyclohexanamine) (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the use of the substance is
as a curing agent for epoxy resin in protective coatings. Based on
EcoSAR analysis of test data on analogous aliphatic amines, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 44 ppb of the PMN substance in surface waters. As described in
the PMN, the substance is not released to surface waters. Therefore,
EPA has not determined that the proposed manufacturing, processing, or
use of the substance may present an unreasonable risk. EPA has
determined, however, that any release of manufacturing or processing
streams containing the PMN substance resulting in surface water
concentrations exceeding 44 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10363.

PMN Number P-10-53

    Chemical name: Halogenated aromatic amine (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as
a reactant for the manufacture of a pesticide. Based on EcoSAR analysis
of test data on analogous aromatic amines, EPA predicts toxicity to
aquatic organisms may occur at concentrations that exceed 2 ppb of the
PMN substance in surface waters. As described in the PMN, the substance
is not released to surface waters. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 2 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
porous pot test (OPPTS Test Guideline 835.3220); a fish acute toxicity
test, freshwater and marine (OPPTS Test Guideline 850.1075); an aquatic
invertebrate acute toxicity test, freshwater daphnids (OPPTS Test
Guideline 850.1010); and an algal toxicity test, tiers I and II (OPPTS
Test Guideline 850.5400) would help characterize the environmental
effects of the PMN substance.
    CFR citation: 40 CFR 721.10364.

PMN Number P-10-56

    Chemical name: Butanoic acid, 3-mercapto-2-methyl-, ethyl ester.
    CAS number: 888021-82-7.
    Basis for action: The PMN states that the substance will be used as
an ingredient in fragrance compounds. Based on EcoSAR analysis of test
data on analogous esters and thiols, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 8 ppb of the PMN
substance in surface waters. At the maximum annual manufacturing and
importation production levels described in the PMN, releases of the PMN
substance are not expected to result in surface water concentrations
that exceed 8 ppb. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance resulting in surface water concentrations exceeding 8 ppb, or
exceedance of the annual maximum manufacturing and importation limit of
100 kilograms may cause significant adverse environmental effects.
Based on this information, the PMN substance meets the concern criteria
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results a fish
acute toxicity test, freshwater and marine (OPPTS Test Guideline
850.1075); an aquatic invertebrate acute toxicity test, freshwater
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test,
tiers I and II (OPPTS Test Guideline 850.5400) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10365.

PMN Number P-10-76

    Chemical name: Benzene, 4-bromo-1,2-dimethyl-.
    CAS number: 583-71-1.
    Basis for action: The PMN states that the substance will be used as
a raw material used for production of 1,1-biphenyl,3,3',4,4'-
tetramethyl. Based on EcoSAR analysis of test data on analogous neutral
organic chemicals, EPA predicts toxicity to aquatic organisms may occur
at concentrations that exceed 30 ppb of the PMN substance in surface
waters. As described in the PMN, releases of the PMN substance are not
expected to result in surface water concentrations that exceed 30 ppb.
Therefore, EPA has not determined that the proposed manufacturing,
processing, or use of the substance may present an unreasonable risk.
EPA has determined, however, that any use of the substance resulting in
surface water concentrations exceeding 30 ppb may cause significant
adverse environmental effects. Based on this information, the PMN
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
simulation test to assess the biodegradability of chemicals discharged
in wastewater (OECD Test Guideline 314); a fish acute toxicity test,
freshwater and marine (OPPTS Test Guideline 850.1075); an aquatic
invertebrate acute toxicity test, freshwater daphnids (OPPTS Test
Guideline 850.1010); and an algal toxicity test, tiers I and II (OPPTS
Test Guideline 850.5400) would help characterize the environmental
effects of the PMN substance.
    CFR citation: 40 CFR 721.10366.

PMN Number P-10-83

    Chemical name: Hydroxy-aryl, polymer with substituted benzene,
cyanate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a resin component. Based
on EcoSAR analysis of test data on analogous neutral organic chemicals,
EPA predicts toxicity to aquatic organisms may occur at concentrations
that exceed 3 ppb of the PMN substance in surface waters. As described
in the PMN, releases of the substance are not expected to result in
surface water concentrations that exceed 3 ppb. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 3 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a water
solubility test (OECD Test Guideline 105); a fish early-life stage
toxicity test (OPPTS Test Guideline 850.1400); and a daphnid chronic
toxicity test (OPPTS Test Guideline 850.1300) would help characterize
the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10367.

PMN Number P-10-84

    Chemical name: Triphenodioxazine derivatives (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a dispersion additive for
printing ink. Based on EcoSAR analysis of test data on analogous
aliphatic amines and diamines, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 1 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any use
of the substance resulting in surface water concentrations exceeding 1
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an
algal toxicity test, tiers I and II (OPPTS Test Guideline 850.5400)
would help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10368.

PMN Number P-10-88

    Chemical name: Carbonic acid, diphenyl ester, polymer with diphenyl
P-methylphosphonate and 4,4'-(1-methylethylidene)bis[phenol].
    CAS number: 77226-90-5.
    Basis for action: The PMN states that the substance will be used as
a flame retardant and flame retardant additive where the particle size
is greater than 10 microns. Based on analysis of test data on analogous
respirable, poorly soluble particulates, EPA identified concerns for
lung overload from inhalation exposures of the PMN substance. For the
uses described in the PMN, significant worker and general population
exposure is unlikely, as exposure to respirable particles is not
expected. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the substance may present an
unreasonable risk. EPA has determined, however, that use of the
substance other than as as a flame retardant and flame retardant
additive where the particle size is greater than 10 microns, may result
in significant human exposures to the respirable form of the PMN
substance. Based on this information, the PMN substance meets the
concern criteria at Sec.  721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) with a 60-
day holding period would help characterize the human health effects of
the PMN substance.
    CFR citation: 40 CFR 721.10369.

PMN Number P-10-99

    Chemical name: Phosphonic acid, p-octyl-, lanthanum (3+) salt
(2:1).
    CAS number: 1186211-38-0.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a modifier for polymers.
Based on EcoSAR analysis of test data on analogous lanthanum salts, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 8 ppb of the PMN substance in surface waters. As described in
the PMN, releases of the PMN substance are not expected to result in
surface water concentrations that exceed 8 ppb. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance resulting in surface water
concentrations exceeding 8 ppb may cause significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
simulated biodegradability test (OECD Test Guideline 314); a fish acute
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075);
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS
Test Guideline 850.1010); and an algal toxicity test, tiers I and II
(OPPTS Test Guideline 850.5400) would help characterize the
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10370.

PMN Number P-10-136

    Chemical names: (P-10-136, Chemical A) Butanoic acid, 3-mercapto-
,1,1'-[2,2-bis[(substituted-1-oxoalkoxy)methyl]-1,3-propanediyl] ester
(generic) and (P-10-136, Chemical B) Butanoic acid, 3-mercapto-,1,1'-
[2-(hydroxymethyl)-2-(substituted-1-oxoalkoxy)methyl)-1,3-propanediyl]
ester (generic).
    CAS numbers: Not available.
    Basis for action: The PMN states that the substance will be used as
a monomer for acryl-based UV-curing coatings, inks, and adhesives.
Based on test data on the PMN substance, EPA identified concerns for
systemic toxicity, mutagenic effects, dermal sensitization and
neurotoxicity from dermal and inhalation exposures to the PMN
substance. Further, based on test data on the PMN substance, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 2 ppb of the PMN substance in surface waters. For the uses
described in the PMN, significant worker exposure is unlikely, as
dermal and inhalation exposures are low, and the substance is not
released to surface waters. Therefore, EPA has not determined that the
proposed processing or use of the substance may present an unreasonable
risk. EPA has determined, however, that domestic manufacture, use other
than as described in the PMN, or any use of the substance resulting in
surface water concentrations exceeding 2 ppb may cause serious health
effects and significant environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(3)(i) and (b)(4)(i).
    Recommended testing: EPA has determined that the results of a
mammalian bone marrow chromosomal aberration test (OPPTS Test Guideline
870.5385) by the intraperitoneal route; a reproduction/developmental
toxicity screening test (OECD Test Guideline 421); a fish early-life
stage toxicity test (OPPTS Test Guideline 850.1400); and a daphnid
chronic toxicity test (OPPTS Test Guideline 850.1300) would help
characterize the human health and environmental effects of the PMN
substance.
    CFR citations: 40 CFR 721.10371 (P-10-136, Chemical A) and 40 CFR
721.10372 (P-10-136, Chemical B).

PMN Number P-10-153

    Chemical name: 1H-Imidazole, 1-(1-methylethyl)-.
    CAS number: 4532-96-1.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a chemical intermediate.
Based on test data on the PMN substance, and EcoSAR analysis of test
data on analogous imidazoles, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 70 ppb of the PMN
substance in surface waters. As described in the PMN, the substance is
not released to surface waters. Therefore, EPA has not determined that
the proposed manufacturing, processing, or use of the substance may
present an unreasonable risk. EPA has determined, however, that any use
of the substance other than as a chemical intermediate, or any use of
the substance resulting in surface water concentrations exceeding 70
ppb may cause significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(4)(i) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test--CO2 in sealed vessels (OPPTS Test
Guideline 835.3140 or OECD Test Guideline 310); a fish acute toxicity
test, freshwater and marine (OPPTS Test Guideline 850.1075); an aquatic
invertebrate acute toxicity test, freshwater daphnids (OPPTS Test
Guideline 850.1010); and an algal toxicity test, tiers I and II (OPPTS
Test Guideline 850.5400) would help characterize the environmental
effects of the PMN substance.
    CFR citation: 40 CFR 721.10373.

PMN Number P-10-163

    Chemical name: Silane, (3-chloro- propoxy)dimethyl(l-methylethyl)-.
    CAS number: 1191036-21-1.
    Basis for action: The PMN states that the substance will be used as
an isolated intermediate in the preparation of a lithium reagent. Based
on the expected alkylating agent potential of the PMN substance, and
analysis of test data on analogous substances, EPA identified concerns
for oncogenicity, mutagenicity, developmental toxicity, liver toxicity,
irritation, and possible corrosion to all tissues to workers exposed to
the PMN substance. Further, based on EcoSAR analysis of test data on
analogous neutral organic chemicals, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 2 ppb of the PMN
substance in surface waters. As described in the PMN, worker inhalation
and dermal exposures are not expected due to the use of organic vapor
respirators, impervious gloves and goggles, and environmental releases
to surface waters are not expected. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance without the use of impervious gloves, goggles, and
organic vapor respirators, where there is a potential of dermal or
inhalation exposure; or any use of the substance resulting in surface
water concentrations exceeding 2 ppb, may cause serious health effects
and significant adverse environmental effects. Based on this
information, the PMN substance meets the concern criteria at Sec.
721.170(b)(1)(i)(C), (b)(3)(ii), and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a
bacterial reverse mutation test (OPPTS Test Guideline 870.5100); a
mammalian erythrocyte micronucleus test (OPPTS Test Guideline 870.5395)
via the intraperitoneal route; an acute dermal irritation test (OPPTS
Test Guideline 870.2500); a skin sensitization test (OPPTS Test
Guideline 870.2600); a repeated dose 28-day oral toxicity test (OPPTS
Test Guideline 870.3050) in rodents; a fish acute toxicity test (OPPTS
Test Guideline 850.1075); an aquatic invertebrate acute toxicity test,
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal
toxicity test, tiers I and II (OPPTS Test Guideline 850.5400) would
help characterize the human health and environmental effects of the PMN
substance.
    CFR citation: 40 CFR 721.10374.

PMN Number P-10-200

    Chemical name: Hydroxypropyl methacrylate, reaction products with
propylene oxide and ethylene oxide, copolymer with N-vinyl caprolactam
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an oilfield polymer.
Based on test data on the PMN substance, and EcoSAR analysis of test
data on analogous nonionic polymers, EPA predicts toxicity to aquatic
organisms may occur at concentrations that exceed 155 ppb of the PMN
substance in surface waters. As described in the PMN, releases of the
PMN substance are not expected to result in surface water
concentrations that exceed 155 ppb. Therefore, EPA has not determined
that the proposed manufacturing, processing, or use of the substance
may present an unreasonable risk. EPA has determined, however, that any
use of the substance resulting in surface water concentrations
exceeding 155 ppb may cause significant adverse environmental effects.
Based on this information, the PMN substance meets

the concern criteria at Sec.  721.170(b)(4)(i) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would
help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10375.

PMN Number P-10-222

    Chemical name: Alkyltin halide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an alkylating agent.
Based on test data on a structurally similar substance, EPA identified
concerns for immunotoxicity, asthma, and sensitization from exposure to
the PMN substance via the inhalation and dermal route. Further, based
on EcoSAR analysis of test data on analogous tin compounds, EPA
predicts toxicity to aquatic organisms may occur at concentrations that
exceed 22 ppb of the PMN substance in surface waters. For the use
described in the PMN, worker inhalation and dermal exposures are
expected to be minimal and releases of the PMN substance to surface
waters are not expected to result in surface water concentrations that
exceed 22 ppb. Therefore, EPA has not determined that the proposed
manufacturing, processing, or use of the PMN substance may present an
unreasonable risk. EPA has determined, however, that any use of the
substance other than as described in the PMN, or any release of the
substance resulting in surface water concentrations exceeding 22 ppb,
may cause serious health effects and significant adverse environmental
effects. Based on this information, the PMN substance meets the concern
criteria at Sec.  721.170(b)(3)(ii) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute
toxicity test (OPPTS Test Guideline 850.1075); an aquatic invertebrate
acute toxicity test, freshwater daphnids (OPPTS Test Guideline
850.1010); and an algal toxicity test, tiers I and II (OPPTS Test
Guideline 850.5400) would help characterize the human health and
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10376.

PMN Number P-10-247

    Chemical names: (P-10-247, Chemical A) 1,2-Cyclohexanedicarboxylic
acid, benzyl C8-10-isoalkyl esters, C9-rich and (P-10-247, Chemical B)
1,2-Cyclohexanedicarboxylic acid, benzyl nonyl ester, branched and
linear.
    CAS numbers: (P-10-247, Chemical A) 1190265-49-6 and (P-10-247,
Chemical B) 1190264-82-4.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an additive for polymers.
Based on test data on the PMN substance, EPA identified concerns for
skin and eye irritation via the dermal route. In addition, based on
test data on a structurally similar compound, EPA identified concerns
for systemic health effects. Further, based on EcoSAR analysis of test
data on analogous esters, EPA predicts toxicity to aquatic organisms
may occur at concentrations that exceed 1 ppb of the PMN substance in
surface waters. As described in the PMN, worker exposure to the
substance is expected to be minimal due to the use of impervious
gloves, and releases of the substance are not expected to result in
surface water concentrations that exceed 1 ppb. Therefore, EPA has not
determined that the proposed manufacturing, processing, or use of the
substance may present an unreasonable risk. EPA has determined,
however, that any use of the substance without the use of impervious
gloves where there is a potential for dermal exposure, or any use of
the substance resulting in surface water concentrations exceeding 1
ppb, may cause serious health effects and significant adverse
environmental effects. Based on this information, the PMN substance
meets the concern criteria at Sec.  721.170(b)(3)(i), (b)(3)(ii), and
(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready
biodegradability test (OPPTS Test Guideline 835.3110); a porous pot
test (OPPTS Test Guideline 835.3220); a combined chronic toxicity/
carcinogenicity test (OPPTS Test Guideline 870.4300); a fish early-life