[Federal Register Volume 79, Number 64 (Thursday, April 3, 2014)]
[Notices]
[Page 18684]
[FR Doc No: 2014-07476]

-----------------------------------------------------------------------

DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. ER14-1596-000]

Lone Valley Solar Park II LLC; Supplemental Notice That Initial
Market-Based Rate Filing Includes Request for Blanket Section 204
Authorization

    This is a supplemental notice in the above-referenced proceeding of
Lone Valley Solar Park II LLC's application for market-based rate
authority, with an accompanying rate tariff, noting that such
application includes a request for blanket authorization, under 18 CFR
part 34, of future issuances of securities and assumptions of
liability.
    Any person desiring to intervene or to protest should file with the
Federal Energy Regulatory Commission, 888 First Street NE., Washington,
DC 20426, in accordance with Rules 211 and 214 of the Commission's
Rules of Practice and Procedure (18 CFR 385.211 and 385.214). Anyone
filing a motion to intervene or protest must serve a copy of that
document on the Applicant.
    Notice is hereby given that the deadline for filing protests with
regard to the applicant's request for blanket authorization, under 18
CFR part 34, of future issuances of securities and assumptions of
liability, is April 17, 2014.
    The Commission encourages electronic submission of protests and
interventions in lieu of paper, using the FERC Online links at http://www.ferc.gov. To facilitate electronic service, persons with Internet
access who will eFile a document and/or be listed as a contact for an
intervenor must create and validate an eRegistration account using the
eRegistration link. Select the eFiling link to log on and submit the
intervention or protests.
    Persons unable to file electronically should submit an original and
5 copies of the intervention or protest to the Federal Energy
Regulatory Commission, 888 First Street NE., Washington, DC 20426.
    The filings in the above-referenced proceeding are accessible in
the Commission's eLibrary system by clicking on the appropriate link in
the above list. They are also available for review in the Commission's
Public Reference Room in Washington, DC. There is an eSubscription link
on the Web site that enables subscribers to receive email notification
when a document is added to a subscribed docket(s). For assistance with
any FERC Online service, please email<EMAIL_ADDRESS>or
call<PHONE_NUMBER> (toll free). For TTY, call<PHONE_NUMBER>.

    Dated: March 28, 2014.
Nathaniel J. Davis, Sr.,
Deputy Secretary.
[FR Doc. 2014-07476 Filed 4-2-14; 8:45 am]
BILLING CODE 6717-01-P


[Federal Register Volume 76, Number 99 (Monday, May 23, 2011)]
[Notices]
[Page 29744]
[FR Doc No: 2011-12601]

-----------------------------------------------------------------------

DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. RC11-3-000]

Monongahela Power Company, West Penn Power Company, The Potomac
Edison Company, PJM Interconnection, L.L.C.; Notice of Filing

    Take notice that on May 13, 2011, Monongahela Power Company, West
Penn Power Company, The Potomac Edison Company (collectively, the
Designated FirstEnergy Utilities), and PJM Interconnection, L.L.C.
filed a joint petition requesting that the Federal Energy Regulatory
Commission (Commission) authorize the Designated FirstEnergy Utilities
to intervene in a Enforcement Hearing, being conducted pursuant to the
Commission-approved Compliance Monitoring and Enforcement Program, and
grant any such waivers as are necessary to allow them to participate in
the Enforcement Hearing as a Participant.
    Any person desiring to intervene or to protest this filing must
file in accordance with Rules 211 and 214 of the Commission's Rules of
Practice and Procedure (18 CFR 385.211, 385.214). Protests will be
considered by the Commission in determining the appropriate action to
be taken, but will not serve to make protestants parties to the
proceeding. Any person wishing to become a party must file a notice of
intervention or motion to intervene, as appropriate. Such notices,
motions, or protests must be filed on or before the comment date. On or
before the comment date, it is not necessary to serve motions to
intervene or protests on persons other than the Applicant.
    The Commission encourages electronic submission of protests and
interventions in lieu of paper using the ``eFiling'' link at http://www.ferc.gov. Persons unable to file electronically should submit an
original and 14 copies of the protest or intervention to the Federal
Energy Regulatory Commission, 888 First Street, NE., Washington, DC
20426.
    This filing is accessible on-line at http://www.ferc.gov, using the
``eLibrary'' link and is available for review in the Commission's
Public Reference Room in Washington, DC. There is an ``eSubscription''
link on the Web site that enables subscribers to receive e-mail
notification when a document is added to a subscribed docket(s). For
assistance with any FERC Online service, please e-mail
<EMAIL_ADDRESS>or call<PHONE_NUMBER> (toll free). For
TTY, call<PHONE_NUMBER>.
    Comment Date: 5 p.m. Eastern Time on May 27, 2011.

    Dated: May 17, 2011.
Kimberly D. Bose,
Secretary.
[FR Doc. 2011-12601 Filed 5-20-11; 8:45 am]
BILLING CODE 6717-01-P


[Federal Register Volume 84, Number 250 (Tuesday, December 31, 2019)]
[Proposed Rules]
[Pages 72260-72262]
[FR Doc No: 2019-27929]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

14 CFR Part 39

[Docket No. FAA-2019-0990; Product Identifier 2019-NM-122-AD]
RIN 2120-AA64

Airworthiness Directives; The Boeing Company Airplanes

AGENCY: Federal Aviation Administration (FAA), DOT.

ACTION: Notice of proposed rulemaking (NPRM).

-----------------------------------------------------------------------

SUMMARY: The FAA proposes to adopt a new airworthiness directive (AD)
for all The Boeing Company Model 747-100, 747-100B, 747-100B SUD, 747-
200B, 747-200C, 747-200F, 747-300, 747-400, 747-400D, 747-400F, 747SR,
and 747SP series airplanes. This proposed AD was prompted by reports of
cracks of the upper splice fittings. This proposed AD would require
repetitive detailed inspections and open hole high frequency eddy
current (HFEC) inspections of the upper splice fittings for cracks and
applicable on-condition actions. The FAA is proposing this AD to
address the unsafe condition on these products.

DATES: The FAA must receive comments on this proposed AD by February
14, 2020.

ADDRESSES: You may send comments, using the procedures found in 14 CFR
11.43 and 11.45, by any of the following methods:
     Federal eRulemaking Portal: Go to https://www.regulations.gov. Follow the instructions for submitting comments.
     Fax:<PHONE_NUMBER>.
     Mail: U.S. Department of Transportation, Docket
Operations, M-30, West Building Ground Floor, Room W12-140, 1200 New
Jersey Avenue SE, Washington, DC 20590.
     Hand Delivery: Deliver to Mail address above between 9
a.m. and 5 p.m., Monday through Friday, except Federal holidays.
    For service information identified in this NPRM, contact Boeing
Commercial Airplanes, Attention: Contractual & Data Services (C&DS),
2600 Westminster Blvd., MC 110-SK57, Seal Beach, CA 90740-5600;
telephone<PHONE_NUMBER>; internet https://www.myboeingfleet.com. You may
view this referenced service information at the FAA, Transport
Standards Branch, 2200 South 216th St., Des Moines, WA. For information
on the availability of this material at the FAA, call<PHONE_NUMBER>. It
is also available on the internet at https://www.regulations.gov by
searching for and locating Docket No. FAA-2019-0990.

Examining the AD Docket

    You may examine the AD docket on the internet at https://www.regulations.gov by searching for and locating Docket No. FAA-2019-
0990; or in person at Docket Operations between 9 a.m. and 5 p.m.,
Monday through Friday, except Federal holidays. The AD docket contains
this NPRM, the regulatory evaluation, any comments received, and other
information. The street address for Docket Operations is listed above.
Comments will be available in the AD docket shortly after receipt.

FOR FURTHER INFORMATION CONTACT: Bill Ashforth, Aerospace Engineer,
Airframe Section, FAA, Seattle ACO Branch, 2200 South 216th St., Des
Moines, WA 98198; phone and fax:<PHONE_NUMBER>; email:
<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION:

Comments Invited

    The FAA invites you to send any written relevant data, views, or
arguments about this proposal. Send your comments to an address listed
under the ADDRESSES section. Include ``Docket No. FAA-2019-0990;
Product Identifier 2019-NM-122-AD'' at the beginning of your comments.
The FAA specifically invites comments on the overall regulatory,
economic, environmental, and energy aspects of this NPRM. The FAA will
consider all comments received by the closing date and may amend this
NPRM because of those comments.
    The FAA will post all comments received, without change, to https://www.regulations.gov, including any personal information you provide.
The FAA will also post a report summarizing each substantive verbal
contact received about this proposed AD.

Discussion

    The FAA has received reports of cracks of the upper splice fittings
at station (STA) 2598. There have been a total of seven cracks reported
on the upper splice fittings on six different airplanes. During
accomplishment of Boeing Service Bulletin 747-53A2473, an operator
reported a crack approximately 0.30 inches long at a fastener hole in
the splice fitting at STA 2598. The crack was in the outboard flange at
a location which is outside of the area inspected in accordance with
Boeing Service Bulletin 747-53A2473. The airplane had accumulated
112,500 flight hours and 18,784 flight cycles when the crack was found.
Ground spoiler buffet loading contributes significantly to maximum
fatigue damage in the area. This condition, if not addressed, could
result in undetected fatigue cracks of the bulkhead splice fitting,
which could lead to failure in the critical attach structure and loss
of the horizontal stabilizer, and adversely affect the structural
integrity of the airplane.

Related Service Information Under 1 CFR Part 51

    The FAA reviewed Boeing Alert Requirements Bulletin 747-53A2899 RB,
dated April 5, 2019. The service information describes procedures for
repetitive detailed inspections and open

hole HFEC inspections of the left and right upper splice fittings for
cracks and applicable on-condition actions. On-condition actions
include repair.
    This service information is reasonably available because the
interested parties have access to it through their normal course of
business or by the means identified in the ADDRESSES section.

FAA's Determination

    The FAA is proposing this AD because the agency evaluated all the
relevant information and determined the unsafe condition described
previously is likely to exist or develop in other products of the same
type design.

Proposed AD Requirements

    This proposed AD would require accomplishment of the actions
identified in Boeing Alert Requirements Bulletin 747-53A2899 RB, dated
April 5, 2019, described previously, except for any differences
identified as exceptions in the regulatory text of this proposed AD.
    For information on the procedures and compliance times, see this
service information at https://www.regulations.gov by searching for and
locating Docket No. FAA-2019-0990.

Explanation of Requirements Bulletin

    The FAA worked in conjunction with industry, under the
Airworthiness Directive Implementation Aviation Rulemaking Committee
(AD ARC), to enhance the AD system. One enhancement is a process for
annotating which steps in the service information are ``required for
compliance'' (RC) with an AD. Boeing has implemented this RC concept
into Boeing service bulletins.
    In an effort to further improve the quality of ADs and AD-related
Boeing service information, a joint process improvement initiative was
worked between the FAA and Boeing. The initiative resulted in the
development of a new process in which the service information more
clearly identifies the actions needed to address the unsafe condition
in the ``Accomplishment Instructions.'' The new process results in a
Boeing Requirements Bulletin, which contains only the actions needed to
address the unsafe condition (i.e., only the RC actions).

Costs of Compliance

    The FAA estimates that this proposed AD affects 125 airplanes of
U.S. registry. The FAA estimates the following costs to comply with
this proposed AD:

                                      Estimated Costs for Required Actions
----------------------------------------------------------------------------------------------------------------
                                                                                Cost on U.S.
             Action                     Labor cost          Parts cost     Cost per product        operators
----------------------------------------------------------------------------------------------------------------
Repetitive detailed inspections  5 work-hours x $85 per               $0  $425 per            $53,125 per
 and open hole HFEC inspections.  hour = $425 per                          inspection cycle.   inspection cycle.
                                  inspection cycle.
----------------------------------------------------------------------------------------------------------------

    The FAA has received no definitive data that would enable the
agency to provide cost estimates for the on-condition actions specified
in this proposed AD.

Authority for This Rulemaking

    Title 49 of the United States Code specifies the FAA's authority to
issue rules on aviation safety. Subtitle I, section 106, describes the
authority of the FAA Administrator. Subtitle VII: Aviation Programs,
describes in more detail the scope of the Agency's authority.
    The FAA is issuing this rulemaking under the authority described in
Subtitle VII, Part A, Subpart III, Section 44701: ``General
requirements.'' Under that section, Congress charges the FAA with
promoting safe flight of civil aircraft in air commerce by prescribing
regulations for practices, methods, and procedures the Administrator
finds necessary for safety in air commerce. This regulation is within
the scope of that authority because it addresses an unsafe condition
that is likely to exist or develop on products identified in this
rulemaking action.
    This proposed AD is issued in accordance with authority delegated
by the Executive Director, Aircraft Certification Service, as
authorized by FAA Order 8000.51C. In accordance with that order,
issuance of ADs is normally a function of the Compliance and
Airworthiness Division, but during this transition period, the
Executive Director has delegated the authority to issue ADs applicable
to transport category airplanes and associated appliances to the
Director of the System Oversight Division.

Regulatory Findings

    The FAA has determined that this proposed AD would not have
federalism implications under Executive Order 13132. This proposed AD
would not have a substantial direct effect on the States, on the
relationship between the national Government and the States, or on the
distribution of power and responsibilities among the various levels of
government.
    For the reasons discussed above, I certify this proposed
regulation:
    (1) Is not a ``significant regulatory action'' under Executive
Order 12866,
    (2) Will not affect intrastate aviation in Alaska, and
    (3) Will not have a significant economic impact, positive or
negative, on a substantial number of small entities under the criteria
of the Regulatory Flexibility Act.

List of Subjects in 14 CFR Part 39

    Air transportation, Aircraft, Aviation safety, Incorporation by
reference, Safety.

The Proposed Amendment

    Accordingly, under the authority delegated to me by the
Administrator, the FAA proposes to amend 14 CFR part 39 as follows:

PART 39--AIRWORTHINESS DIRECTIVES

0
1. The authority citation for part 39 continues to read as follows:

    Authority:  49 U.S.C. 106(g), 40113, 44701.

Sec.  39.13  [Amended]

0
2. The FAA amends Sec.  39.13 by adding the following new airworthiness
directive (AD):

The Boeing Company: Docket No. FAA-2019-0990; Product Identifier
2019-NM-122-AD.

(a) Comments Due Date

    The FAA must receive comments by February 14, 2020.

(b) Affected ADs

    None.

(c) Applicability

    This AD applies to all The Boeing Company Model 747-100, 747-
100B, 747-100B SUD, 747-200B, 747-200C, 747-200F, 747-300, 747-400,
747-400D, 747-400F, 747SR, and 747SP series airplanes, certificated
in any category.

(d) Subject

    Air Transport Association (ATA) of America Code 53, Fuselage.

(e) Unsafe Condition

    This AD was prompted by reports of cracks of the upper splice
fittings. The FAA is issuing this AD to address cracks of the upper
splice fittings, which could result in undetected fatigue cracks of
the bulkhead splice fitting, lead to failure in the critical attach
structure and loss of the horizontal stabilizer, and adversely
affect the structural integrity of the airplane.

(f) Compliance

    Comply with this AD within the compliance times specified,
unless already done.

(g) Required Actions

    Except as specified by paragraph (h) of this AD: At the
applicable times specified in the ``Compliance'' paragraph of Boeing
Alert Requirements Bulletin 747-53A2899 RB, dated April 5, 2019, do
all applicable actions identified in, and in accordance with, the
Accomplishment Instructions of Boeing Alert Requirements Bulletin
747-53A2899 RB, dated April 5, 2019.

    Note 1 to paragraph (g):  Guidance for accomplishing the actions
required by this AD can be found in Boeing Alert Service Bulletin
747-53A2899, dated April 5, 2019, which is referred to in Boeing
Alert Requirements Bulletin 747-53A2899 RB, dated April 5, 2019.

(h) Exceptions to Service Information Specifications

    (1) For purposes of determining compliance with the requirements
of this AD: Where Boeing Alert Requirements Bulletin 747-53A2899 RB,
dated April 5, 2019, uses the phrase ``the original issue date of
Requirements Bulletin 747-53A2899 RB,'' this AD requires using ``the
effective date of this AD.''
    (2) Where Boeing Alert Requirements Bulletin 747-53A2899 RB,
dated April 5, 2019, specifies contacting Boeing for repair
instructions: This AD requires doing the repair using a method
approved in accordance with the procedures specified in paragraph
(i) of this AD.

(i) Alternative Methods of Compliance (AMOCs)

    (1) The Manager, Seattle ACO Branch, FAA, has the authority to
approve AMOCs for this AD, if requested using the procedures found
in 14 CFR 39.19. In accordance with 14 CFR 39.19, send your request
to your principal inspector or local Flight Standards District
Office, as appropriate. If sending information directly to the
manager of the certification office, send it to the attention of the
person identified in paragraph (j)(1) of this AD. Information may be
emailed to<EMAIL_ADDRESS>    (2) Before using any approved AMOC, notify your appropriate
principal inspector, or lacking a principal inspector, the manager
of the local flight standards district office/certificate holding
district office.
    (3) An AMOC that provides an acceptable level of safety may be
used for any repair, modification, or alteration required by this AD
if it is approved by The Boeing Company Organization Designation
Authorization (ODA) that has been authorized by the Manager, Seattle
ACO Branch, FAA, to make those findings. To be approved, the repair
method, modification deviation, or alteration deviation must meet
the certification basis of the airplane, and the approval must
specifically refer to this AD.

(j) Related Information

    (1) For more information about this AD, contact Bill Ashforth,
Aerospace Engineer, Airframe Section, FAA, Seattle ACO Branch, 2200
South 216th St., Des Moines, WA 98198; phone and fax:<PHONE_NUMBER>;
email<EMAIL_ADDRESS>    (2) For service information identified in this AD, contact
Boeing Commercial Airplanes, Attention: Contractual & Data Services
(C&DS), 2600 Westminster Blvd., MC 110-SK57, Seal Beach, CA 90740-
5600; telephone<PHONE_NUMBER>; internet https://www.myboeingfleet.com. You may view this referenced service
information at the FAA, Transport Standards Branch, 2200 South 216th
St., Des Moines, WA. For information on the availability of this
material at the FAA, call<PHONE_NUMBER>.

    Issued in Des Moines, Washington, on December 17, 2019.
Michael Kaszycki,
Acting Director, System Oversight Division, Aircraft Certification
Service.
[FR Doc. 2019-27929 Filed 12-30-19; 8:45 am]
 BILLING CODE 4910-13-P


Field crop, typical and high-acreage[8,9]

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.0741
                                     1,300
                                    0.00253
                                     1,800
                   Groundboom application of a dry flowable
                     Golf course (fairways, tees, greens)
                                     227
                                     8.96
                                     0.375
                                      40
                                    0.0494
                                     2,000
                                    0.00168
                                     2,800

                         Field-grown ornamental crops

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.0741
                                     1,300
                                    0.00253
                                     1,800

                                      Sod

                                      80
                                    0.0987
                                     1,000
                                    0.00336
                                     1,400

                        Field crop, typical acreage[8]

                          Field crop, high-acreage[9]

                                      200
                                     0.246
                                      410
                                    0.0084
                                      550
Commercial Impregnation of Dry Flowable Formulation on Dry Bulk Fertilizers  (closed system)
                                   9.8 (EC)
                                   0.24 (EC)
                                3.75 lb ai/ton
                                   960 tons
                                     0.512
                                      200
                                    0.0108
                                      750
   On-farm Impregnation of Dry Flowable  Formulation on Dry Bulk Fertilizers
                                     227
                                     8.96
                                     0.375
                                      160
                                     0.246
                                      410
                                    0.0084
                                      550
       Loading/applying granular for tractor-drawn spreader application
                     Golf course (fairways, tees, greens)
                                      8.4
                                      1.7
                                     0.375
                                      40
                                    0.00183
                                    55,000
                                   0.000319
                                    25,000

                                     Sod

                                      80
                                    0.00365
                                    27,000
                                   0.000638
                                    13,000

                             Christmas tree farms

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.00274
                                    36,000
                                   0.000479
                                    17,000
                   Aerial application of liquid formulation
           Nursery (ornamentals, vegetables, trees, container stock)
                                     220

                              37.6 (SL w/gloves)
                                    0.219
                                     0.375
                                      60
                                    0.0717
                                     1,400
                                   0.0000616
                                    76,000

                                      Sod

                                      350
                                     0.419
                                      240
                                   0.000359
                                    13,000

                        Field crop, typical acreage[8]

                         Field crop, high-acreage[9]

                                     1200
                                     1.43

                              0.245 (SL w/gloves)
                                      70

                               410 (SL w/gloves)
                                    0.00123
                                     3,800

                                     0.25

                                     0.957
                                      100
                                   0.000821
                                     5,700

                                     0.19

                                     0.728
                                      140
                                   0.000624
                                     7,500
                Chemigation application of a liquid formulation
                                      Sod
                                      220
                                    0.219
                                     0.375
                                      350
                                     0.419
                                      240
                                   0.000359
                                    13,000

                   Field crop, typical and high-acreage[8,9]

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.0717
                                     1,400
                                   0.0000616
                                    76,000
                 Groundboom application of liquid formulation
                     Golf course (fairways, tees, greens)
                                      220
                                    0.219
                                     0.375
                                      40
                                    0.0478
                                     2,100
                                   0.0000411
                                    110,000

                         Field-grown ornamental crops

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.0717
                                     1,400
                                   0.0000616
                                    76,000

                                      Sod

                                      80
                                    0.0957
                                     1,000
                                   0.0000821
                                    57,000

                        Field crop, typical acreage[8]

                          Field crop, high-acreage[9]

                                      200
                                     0.239
                                      420
                                   0.000205
                                    23,000
Commercial Impregnation of Liquid Formulation on Dry Bulk Fertilizers  (closed system)
                           8.6 (engineering control)
                          0.083 (engineering control)
                                3.75 lb ai/ton
                                   960 tons
                                     0.449
                                      220
                                    0.00374
                                     2,200
      On-farm Impregnation of Liquid Formulation on Dry Bulk Fertilizers
                                     220
                                    0.219
                                    0.375
                                      160
                                     0.191
                                      520
                                   0.000164
                                    28,000
                                  Applicator
                           Aerial spray application
           Nursery (ornamentals, vegetables, trees, container stock)
                                     2.08
                             (engineering control)
                                    0.0049
                             (engineering control)
                                     0.375
                                      60
                                   0.000678
                                    150,000
                                  0.00000138
                                   5,900,000

                                      Sod

                                      350
                                    0.00396
                                    25,000
                                  0.00000804
                                   1,000,000

                        Field crop, typical acreage[8]

                          Field crop, high-acreage[9]

                                     1200
                                    0.0136
                                     7,400
                                   0.0000276
                                    290,000
                         Groundboom spray application
                     Golf course (fairways, tees, greens)
                                     78.6
                                     0.34
                                     0.375
                                      40
                                    0.0171
                                     5,800
                                   0.0000638
                                    36,000

                         Field-grown ornamental crops

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.0257
                                     3,900
                                   0.0000956
                                    24,000

                                      Sod

                                      80
                                    0.0342
                                     2,900
                                   0.000128
                                    18,000

                        Field crop, typical acreage[8]

                          Field crop, high-acreage[9]

                                      200
                                    0.0855
                                     1,200
                                   0.000319
                                     7,300
                       Mechanically-pressurized handgun
              Rights-of-way (e.g., utilities, railroad, roadways)
                                     1,300
                                      3.9
                              0.019 lb ai/gallon
                                 1000 gallons
                                     0.358
                                      280
                                   0.000926
                                     8,700
                 Tractor-drawn Spreader granular application
                     Golf course (fairways, tees, greens)
                                      9.9
                                      1.2
                                     0.375
                                      40
                                    0.00216
                                    46,000
                                   0.000225
                                    36,000

                                     Sod

                                      80
                                    0.0043
                                    23,000
                                    0.00045
                                    18,000

Christmas tree farms

           Nursery (ornamentals, vegetables, trees, container stock)

                                      60
                                    0.00323
                                    31,000
                                   0.000338
                                    24,000
                                    Flagger
                     Flagger for aerial spray application
           Nursery (ornamentals, vegetables, trees, container stock)
                                      11
                                     0.35
                                     0.375
                                      60
                                    0.00359
                                    28,000
                                   0.0000985
                                    82,000

                                      Sod

                                      350
                                    0.0209
                                     4,800
                                   0.000574
                                    14,000

                  Field crop, typical and high-acreage[9,10]

                            Mixer/Loader/Applicator
                          Dry Flowables via Backpack
Railroad, Highway, Roadside, Pipeline and Utility Rights of-Way, Industrial Areas,
Fence Rows, and Other listed Non-crop Sites
                                     8,260
                                     2.58
                              0.019 lb ai/gallon
                                  40 gallons
                                     0.091
                                     1,100
                                   0.0000245
                                    190,000

            Landscaping, turf (lawns, athletic fields, parks, etc.)

                Dry Flowables via Manually-Pressurized Handwand
            Landscaping, turf (lawns, athletic fields, parks, etc.)
                                    100,000
                                      30
                              0.019 lb ai/gallon
                                  40 gallons
                                      1.1
                             0.00474 (SL w/gloves)
                                      91
                             21,000 (SL w/gloves)
                                   0.000285
                                    28,000
              Dry Flowables via Mechanically-pressurized Handgun
                     Golf course (fairways, tees, greens)
                                     1,960
                                      42
                                     0.375
                                       5
                                    0.0533
                                     1,900
                                   0.000985
                                     4,700

            Landscaping, turf (lawns, athletic fields, parks, etc.)

                             Liquids via Backpack
                              Christmas Tree farm
                                     8,260
                                     2.58
                              0.0375 lb ai/gallon
                                  40 gallons
                                     0.18
                                      560
                                   0.0000484
                                    96,000

Railroad, Highway, Roadside, Pipeline and Utility Rights of-Way, Industrial Areas,
Fence Rows, and Other listed Non-crop Sites

           Nursery (ornamentals, vegetables, trees, container stock)

            Landscaping, turf (lawns, athletic fields, parks, etc.)

                              0.019 lb ai/gallon

                                     0.091
                                     1,100
                                   0.0000245
                                    190,000
                   Liquids via Manually-pressurized Handwand
            Landscaping, turf (lawns, athletic fields, parks, etc.)
                                    100,000
                                      30
                              0.019 lb ai/gallon
                                  40 gallons
                                      1.1
                             0.00474 (SL w/gloves)
                                      91
                             21,000 (SL w/gloves)
                                   0.000285
                                    28,000
                 Liquids via Mechanically-pressurized Handgun
                     Golf course (fairways, tees, greens)
                                     1,140
                                      1.9
                                     0.375
                                       5
                                     0.031
                                     3,200
                                   0.0000445
                                    100,000

            Landscaping, turf (lawns, athletic fields, parks, etc.)

           Nursery (ornamentals, vegetables, trees, container stock)
                                     1,300
                                      3.9
                              0.0375 lb ai/gallon
                                 1000 gallons
                                     0.707
                                      140
                                    0.00183
                                     4,400
                            Granulars via Backpack
                              Christmas Tree farm
                                      15
                                     23.8
                                     0.375
                                       5
                                   0.000407
                                    250,000
                                   0.000112
                                    42,000

           Nursery (ornamentals, vegetables, trees, container stock)

                      Water Soluble Packets via Backpack
                         Residential/ Commercial Turf
                                     8,260
                                     2.58
                              0.0033 lb ai/gallon
                                  40 gallons
                                    0.0158
                                     13000
                                  0.00000426
                                   1,100,000
            Water Soluble Packets via Manually-Pressurized Handwand

                                    100,000
                                      30

                                     0.191
                                    140000
                                   0.0000495
                                    160,000
          Water Soluble Packets via Mechanically-Pressurized Handgun

                                     1,350
                                      18
                                 0.287 lb ai/A
                                       5
                                    0.0281
                                     11000
                                   0.000323
                                    14,000
[1]  Based on the "Occupational Pesticide Handler Unit Exposure Surrogate Reference Table" (March 2013); Level of mitigation:  Baseline, Eng. Controls.
[2]  Based on registered and proposed labels.
[3]  Exposure Science Advisory Council Policy #9.1 and Registrant information.
[4]  Dermal Dose = Dermal Unit Exposure (μg/lb ai) x Conversion Factor (0.001 mg/μg) x Application Rate (lb ai/acre) x Area Treated (A/day)  / BW (69 kg).
[5]  Dermal MOE = Dermal NOAEL (100 mg/kg/day) / Dermal Dose (mg/kg/day).
[6]  Inhalation Dose = Inhalation Unit Exposure (μg/lb ai) x Conversion Factor (0.001 mg/μg) x Application Rate (lb ai/acre) x Area Treated (A/day) / BW (80 kg).
[7]  Inhalation MOE = Inhalation NOAEL (2.317, 4.661, or 8.094 mg/kg/day) / Inhalation Dose (mg/kg/day).
[8]  Field crops, typical acreage category covers the following crops:  apples, asparagus, Brassica head and stem, Brassica leafy greens, cabbage, citrus fruits, tree nuts, grapes and berries, edamame, fallow cropping systems, flax, fruiting vegetables, okra, horseradish, lima beans, melons, rhubarb, strawberry, succulent peas, tobacco, turnips, Christmas tree farms (where applicable).
[9]  Field crops, high-acreage crops category covers the following crops: corn, dry shelled peas and beans, mint, peanuts, peppermint, spearmint, potato, soybeans, sugarcane, sunflower, wheat.

9.2	Post-Application Risk Assessment

9.2.1	Inhalation Post-Application Risk Assessment

Based on the Agency's current practices, a quantitative post-application inhalation exposure assessment was not performed for sulfentrazone at this time primarily because of the low acute inhalation toxicity (Toxicity Category III) and the low vapor pressure (8 x 10[-10] mm Hg).  However, there are multiple potential sources of post-application inhalation exposure to individuals performing post-application activities in previously treated fields.  These potential sources include volatilization of pesticides and resuspension of dusts and/or particulates that contain pesticides.  The Agency sought expert advice and input on issues related to volatilization of pesticides from its FIFRA SAP in December 2009, and received the SAP's final report on March 2, 2010.  The Agency is in the process of evaluating the SAP report as well as available post-application inhalation exposure data generated by the ARTF and may, as appropriate, develop policies and procedures, to identify the need for and, subsequently, the way to incorporate occupational post-application inhalation exposure into the Agency's risk assessments.  If new policies or procedures are put into place, the Agency may revisit the need for a quantitative occupational post-application inhalation exposure assessment for sulfentrazone.

Although a quantitative occupational post-application inhalation exposure assessment was not performed, an inhalation exposure assessment was performed for occupational/commercial handlers.  Handler exposure resulting from application of pesticides outdoors is likely to result in higher exposure than post-application inhalation exposure.  Therefore, it is expected that these handler inhalation exposure estimates would be protective of most occupational post-application inhalation exposure scenarios.

9.2.2	Dermal Post-Application Risk Assessment

Most of the registered uses and the proposed use on apples are soil-directed preplant or preemergent uses where no crop foliage is present.  Currently, HED has no transfer coefficients or other data to assess post-application dermal exposures to soil by occupational workers.  In general, such exposures are considered to be negligible.  Therefore, for the soil-directed uses, post-application exposures and risks to occupational workers were not assessed.

The registered uses on turf (golf courses and sod farms) and ornamentals are not specifically soil directed and, therefore, could result in potential post-application exposures.  The short- and intermediate-term post-application exposure scenarios associated with the registered uses of sulfentrazone are summarized in Table <IP_ADDRESS>.  All scenarios resulted in MOEs greater than the LOC of 100 (ranging from 430 to 8,200) on day 0 (12 hours after application) and, therefore, are not of concern to HED.

Table <IP_ADDRESS>.  Occupational Post-application Non-Cancer Exposure and Risk Estimates for Sulfentrazone.
                                   Crop/Site
                                  Activities
                        Transfer Coefficient (cm[2]/hr)
                                  Application
                                Rate (lb ai/A)
                                    DFR[1]
                                  Dermal Dose
                                (mg/kg/day)[2]
                                    MOE[3]
                                  (LOC = 100)
                         Short- and Intermediate-term
      Landscape ornamentals (Container, Field grown Ornamental plantings)
Hand Harvesting, Hand Pruning, Transplanting, Hand Harvesting, Hand Pruning, Scouting, Container Moving, Hand Weeding, Transplanting, Pinching
                                      230
                                     0.375
                                     1.05
                                     0.028
                                     3,200

                              Handset Irrigation
                                     1,900

                                     0.232
                                      430
                                 Golf Courses
                           Maintenance, greens only
                                     2,500
                                     0.375
                                     0.042
                                     0.012
                                     8,200

                                  Maintenance
                                     3,700

                                     0.018
                                     5,500
                                      Sod
             Maintenance, Slab Harvesting, Transplanting/Planting
                                     6,700

                                     0.033
                                     3,100
[1]  DFR = Application Rate x F x (1-D)[t] x 4.54E8 ug/lb x 2.47E-8 acre/cm[2]; where F = 0.25 and D = 0.10 per day.
[2]  Daily Dermal Dose = [DFR (ug/cm[2]) x Transfer Coefficient x 0.001 mg/ug x 8 hrs/day]  BW (69 kg).
[3]  MOE = POD (100 mg/kg/day) / Daily Dermal Dose.

Restricted-Entry Interval

The REI specified on the proposed label is based on the acute toxicity of sulfentrazone.  Sulfentrazone is classified as acute Toxicity Category III for acute oral, acute dermal, and acute inhalation toxicity.  It is classified as Toxicity Category III for eye irritation potential and category IV for skin irritation potential.  It is not a dermal sensitizer.  Short- and intermediate-term post-application risk estimates were not a concern on day 0 (12 hours following application) for all post-application activities.  Under 40 CFR 156.208 (c) (2) (iii), ais classified as Acute III or IV for acute dermal, eye irritation and primary skin irrigation are assigned a 12-hour REI.  Therefore, the [156 subpart K] Worker Protection Statement interim REI of 12 hours is adequate to protect agricultural workers from post-application exposures to sulfentrazone.

10.0	References

Recent RA
J. Van Alstine, et al., 14-JUN-2012; D389082

Scoping Document
K. Lowe, et al., 09-SEP-2009; D369064

HASPOC Memo
D. Smegal, 02-MAR-2012; TXR # 0050684; and
Re-Classification of Peer-Reviewed Developmental Neurotoxicity Study in Rats:  C. Rodriguez, 19-DEC-2011; D389975.

ORE Memo
K. Lowe, D417171; 05-JUN-2014

Dietary Memo
G. Kramer, D417172; 05-JUN-2014

cc:  G. Kramer (RAB1)
RDI:  RAB1 (5/14/14)
 G.F. Kramer:S10957:PY-S:(703)305-5079:7509P:RAB1

Appendix A.  Toxicology Profile and Executive Summaries

The requirements (40 CFR 158.340) for food uses for sulfentrazone are in Table A.1.  Use of the new guideline numbers does not imply that the new (1998) guideline protocols were used.

Table A.1.  Toxicological Data Requirements for Sulfentrazone.
                                     Study
                                   Technical

                                   Required
                                   Satisfied
870.1100    Acute Oral Toxicity
870.1200    Acute Dermal Toxicity
870.1300    Acute Inhalation Toxicity
870.2400    Primary Eye Irritation
870.2500    Primary Dermal Irritation
870.2600    Dermal Sensitization
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
870.3100    Oral Subchronic (rodent)
870.3150    Oral Subchronic (nonrodent)
870.3200    28-Day Dermal
870.3465    28-Day Inhalation
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
870.3700a  Developmental Toxicity (rodent)
870.3700a  Dermal Developmental Toxicity (rodent)
870.3700b  Developmental Toxicity (nonrodent)
870.3800    Reproduction
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
870.4100a  Chronic Toxicity (rodent)
870.4100b  Chronic Toxicity (nonrodent)
870.4200a  Oncogenicity (rat)
870.4200b  Oncogenicity (mouse)
870.4300    Chronic/Oncogenicity
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
870.5100    Mutagenicity -- Gene Mutation - bacterial
870.5300    Mutagenicity -- Gene Mutation - mammalian
870.5xxx    Mutagenicity -- Structural Chromosomal Aberrations
870.5xxx    Mutagenicity -- Other Genotoxic Effects
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
                                      yes
870.6100a  Acute Delayed Neurotoxicity (hen)
870.6100b  90-Day Neurotoxicity (hen)
870.6200a  ACN Screening Battery (rat)
870.6200b  90-Day Neurotoxicity Screening Battery (rat)
870.6300    Develop. Neurotoxicity
                                      no
                                      no
                                      yes
                                      yes
                                      no
                                      --
                                      --
                                      yes
                                      yes
                                      --
870.7485    General Metabolism
870.7600    Dermal Penetration
870.7800    Immunotoxicity
                                      yes
                                      no
                                      yes
                                      yes
                                      --
                                      yes

Table A.2.  Acute Toxicity Profile  -  Sulfentrazone.
                                 Guideline No.
                                  Study Type
                                    MRID(s)
                                    Results
                               Toxicity Category
                                   870.1100
                               Acute oral [rat]
                                   41911605
                         LD50 = 2855 (M & F) mg/kg
                                      III
                                   870.1200
                              Acute dermal [mice]
                                   41911606
                         LD50 = 711 (M & F) mg/kg
                                      III
                                   870.1200
                                 Acute dermal
                                   42286400
                            LD50 >2000 mg/kg/day
                                      III
                                   870.1300
                            Acute inhalation [rat]
                                   42471002
                4-hour, whole body exposure; LC50 >4.13 mg/L
                                      III
                                   870.2400
                         Acute eye irritation [rabbit]
                                   41911608
   Corneal opacity, iritis, diffuse irritation within 24, clearing by day 4
                                      III
                                   870.2500
                       Acute dermal irritation [rabbit]
                                   41911609
                                Non-irritating
                                      IV
                                   870.2600
                        Skin sensitization [Guinea Pig]
                                   41911610
                            Not a Dermal Sensitizer
                                      N/A

Table A.3.  Toxicity Profile for Sulfentrazone
                                Guideline No./
                                  Study Type
                     MRID No. (year)/Classification/ Doses
                                    Results
870.3100
90-Day oral toxicity (rat)
43004601 (1990)
Acceptable/Guideline
0, 300, 1000, 3000, & 7000 ppm,
M:  0, 3.3, 6.7, 19.9, 65.8, 199.3, & 534.9 mg/kg/day
F:  0, 4, 7.7, 23.1, 78.1, 230.5, & 404.3 mg/kg/day
Systemic Toxicity NOAEL = 19.9 mg/kg/day in males and 23.1 mg/kg/day in females.
Systemic Toxicity LOAEL = 65.8 mg/kg/day in males and 78.1 mg/kg/day in females, based on clinical signs of anemia (reduced Hct, HGB, MCV, and MCH values during treatment).
870.3100
90-Day oral toxicity (mice)
43616517 (1993)
Acceptable/Guideline
0, 50, 100, 300, 550, 1000, & 3000 ppm
M: 0, 10.3, 17.8, 60, 108.4, & 194.4 mg/kg/day
F:  0, 13.9, 29, 79.8, 143.6, & 257 mg/kg/day
Systemic Toxicity NOAEL = 60 mg/kg/day in males and 79.8 mg/kg/day in females.
Systemic Toxicity LOAEL = 108.4 mg/kg/day in males and 143.6 mg/kg/day in females, based on decreased body weights, body-weight gains, red blood cells, HGB, Hct, and severity of splenic micropathology (increased incidence and severity of extramedullary hematopoiesis).  Four-week recovery period reversed all the treatment related effects except extramedullary hematopoiesis; however, severity was reduced.
870.3150
90-Day oral toxicity (dog)
42932102 (1992)
Acceptable/Guideline
0, 300, 800 & 2000 ppm
M/F:  0/0, 10/10, 28/28, & 57/73
mg/kg/day
Systemic Toxicity NOAEL = 28 mg/kg/day for males and females.
Systemic Toxicity LOAEL = 57/73 mg/kg/day (M/F), based on decreased body weights (7-10%) and body-weight gains during first 5 weeks of study; decreased HGB, Hct, MCV, and MCH concentration, and increased absolute liver weights and alkaline phosphatase levels, and microscopic changes in the liver and spleen (pigmented sinusoidal microphages in the liver, swollen centrilobular hepatocytes and pigmented reticuloendothelial cells in the spleen).
870.3200
28-Day dermal toxicity (rabbit)
44248301 (1996)
Acceptable/Guideline
0, 10, 30, 100, 300, & 1000 mg/kg/day
Systemic and Dermal Toxicity NOAEL = 1000 mg/kg/day (highest dose tested or HDT).
Systemic and Dermal Toxicity LOAEL was not established.
870.3465
26-Day inhalation toxicity with 28 days of recovery (rat)
49253902 (2013)
Acceptable/Non-Guideline
0, 0.085, 0.256 and 1.71 mg/L
(0, 20, 40, 600 mg/kg/day [M/F])
NOAEL = 0.256 mg/L.
LOAEL = 1.71 mg/L based on significant reduction in RBC parameters, including RBC count, HGB, Hct, MCV, MCH, and/or reticulocytes in male and female rats following 26 days inhalation exposure to the test material.
Portal-of-entry NOAEL = 0.256 mg/L.
Portal-of-entry LOAEL = 1.71 mg/L based on an increased incidence of minimal nasal respiratory epithelial hyperplasia in male and female rats.
870.3700a
Prenatal Developmental (rat)
42932104 (2013)
Acceptable/Guideline
0, 1, 10, 25 & 50 mg/kg/day
Maternal NOAEL = 25 mg/kg/day.
Maternal LOAEL = 50 mg/kg/day, based upon increased relative splenic extramedullary hematopoiesis.
Developmental NOAEL = 10 mg/kg/day.
Developmental LOAEL = 25 mg/kg/day, based upon decreased mean fetal weights, and retardation in skeletal development evidenced by an increased number of litters with any variation and by decreased number of caudal vertebral and metacarpal ossification sites.
870.3700
Prenatal developmental (rat)
43651003 (1992)
Acceptable/Non-Guideline
0, 25, & 50 mg/kg/day
Study was conducted to evaluate external and cardiac abnormalities.
Maternal NOAEL = 25 mg/kg/day.
Maternal LOAEL = 50 mg/kg/day, based on decreased mean body weights during gestation, and decreased litter size.
Developmental NOAEL = 25 mg/kg/day.
Developmental LOAEL = 50 mg/kg/day, based on significant reductions in the number of implantations and percentage of live fetuses, increase in the percentage of early resorptions, and decreased fetal body weights.

Supplemental study to the 1992 Developmental-Toxicity Study in Rats (MRID 42932104).
870.3700
Prenatal dermal developmental (rat)
MRID 42932105 (1992)
Acceptable/Guideline
0, 5, 25, 50, 100, & 250 mg/kg/day
Maternal NOAEL >250 mg/kg/day.
Maternal LOAEL was not established.
Developmental NOAEL = 100 mg/kg/day.
Developmental LOAEL = 250 mg/kg/day, based on decreased fetal body weight; increased incidence of fetal variations: hypoplastic or wavy ribs, incompletely ossified lumbar vertebral arches, and incompletely ossified ischia or pubis; and reduced number of thoracic vertebral and rib ossification sites.
870.3700b
Prenatal Developmental  (rabbit)
MRID 42932106 (1993)
Acceptable/Guideline
0, 100, 250, & 375 mg/kg/day
Maternal NOAEL = 100 mg/kg/day.
Maternal LOAEL = 250 mg/kg/day, based on increased abortions, clinical signs (hematuria and decreased feces), and reduced body-weight gain.
Developmental NOAEL = 100 mg/kg/day.
Developmental LOAEL = 250 mg/kg/day, based on increased resorptions, decreased live fetuses per litter, and decreased fetal weights.
870.3800
Two-Generation reproduction and fertility effects (rat)
43345408 (1994)
Acceptable/Guideline
0, 200, 500, & 700 ppm
M/F:  0, 14/16, 33/40, & 46/56 mg/kg/day
Parental Toxicity NOAEL =14 (M) and 16 (F) mg/kg/day.
Parental Toxicity LOAEL = 33 (M) and 40 (F) mg/kg/day based on decreased maternal body weight/body-weight gain during gestation in both generation (P & F1) and reduced premating body-weight gain in second-generation (F1) males.
Reproductive Toxicity NOAEL = 14 (M) and 16 (F) mg/kg/day.
Reproductive Toxicity LOAEL = 33 (M) and 40 (F) mg/kg/day, based on increased duration of gestation in females and degeneration and/or atrophy of the germinal epithelium of the testes and oligospermia and intratubular degenerated seminal material in the epididymis of F1 males.
Offspring Toxicity NOAEL = 14 (M) and 16 (F) mg/kg/day.
Offspring Toxicity LOAEL = 33 (M) and 40 (F) mg/kg/day, based on reduced prenatal viability (fetal & litter), reduced litter size, increased no. of stillborn pups, reduced pup and litter postnatal survival and decreased pup body weights throughout lactation.
870.3800
One-Generation reproduction and fertility effects (rat)
43869101(1995)
Acceptable/Nonguideline
0, 50, 100, 200, & 500 ppm
F0 M/F:  0, 3.9/4.1, 7.8/13.4, 16/16, & 40/43 mg/kg/day
F1 M/F:  0/0, 4.5/5.0, 9.2/10.1, 18/20, & 45/51 mg/kg/day
Systemic/Developmental Toxicity NOAEL = 20 (F) mg/kg/day.
Systemic/Developmental Toxicity LOAEL = 51 (F) mg/kg/day, (F1 females), based on decrease in pre-mating body-weight gain (10%).
Offspring and Reproductive Toxicity NOAEL = 16
mg/kg/day (M/F) mg/kg/day.
Offspring and Reproductive Toxicity LOAEL F1 = 40 (M/F) mg/kg/day, based on reduced gestation day-20 fetal weights; decreased postnatal day 0, 4, and 7 pup weights; decreased pup survival; delayed vaginal patency; reduced epididymal, prostate, and testicular weights.  Additional information supports the conclusions reached in the two-generation reproduction study (MRID 43345408).
870.4100b
Chronic toxicity (dog)
43345406 (1994)
Acceptable/Guideline
0, 300, 800, and 1800 ppm
M/F:  0, 9.9/10.4, 24.9/29.6, & 61.2/61.9 mg/kg/day
Systemic Toxicity NOAEL = 24.9/29.6 mg/kg/day for males/and females.
Systemic Toxicity LOAEL = 61.2/61.9 mg/kg/day (M/F), based upon compensated normochromic microcytosis.
870.4200
Carcinogenicity rodents (mouse)
43345407 (1994)
Acceptable/Guideline
0, 300, 600, 1000, & 2000 ppm
M/F: 0, 46.6/58.0, 93.9/116.9, 160.5/198.0 & 337.6/407.1 mg/kg/day
Systemic Toxicity NOAEL = 93.9 mg/kg/day for males and 116.9 mg/kg/day for females.
Systemic Toxicity LOAEL = 160.5 mg/kg/day for males and 198.0 mg/kg/day for females, based on dose-related decreases in HGB and Hct by study termination.

No evidence of carcinogenicity.
870.4300
Combined chronic toxicity/carcinogenicity rodents (rat)
43345409 (1994)
Acceptable/Guideline
M: 0, 600, 1000, 2000, & 3000 ppm
F:  0, 300, 600, 1000 & 2000 ppm
M/F:  0/0, 24.3/20, 40/36.4, 82.8/67, & 123.5/124.7 mg/kg/day
Systemic Toxicity NOAEL = 40 mg/kg/day for males and 36.4 mg/kg/day for females.
Systemic Toxicity LOAEL = 82.8 mg/kg/day for males and 67 mg/kg/day for females, based on dose-related decreased body weights (11 & 19%), body-weight gains (13 & 26%), food consumption (13 & 19%), HGB, Hct, MCV, and MCH. Increased nucleated red blood cells and reticulocytes in bone of females at 124.7 mg/kg/day.

No evidence of carcinogenicity.
870.5100
Gene Mutation:  Ames assay
Gene Mutation:  HGPRT
41911611 (1986)
Acceptable/Guideline
Salmonella typhimurium strains
TA1535, TA1538, TA1537, TA98, and TA100 were exposed to sulfentrazone technical (95.5%) at concentrations of 100-10,000 ug/plate with or without S9 activation (both trials).
No evidence of compound-induced cytotoxicity was evident either in presence or in absence of S9 activation.  The positive controls induced the expected mutagenic responses in the appropriate tester strain.  Sulfentrazone was considered not mutagenic under any test condition.
870.5300
In vitro mammalian cell gene mutation assay (mouse lymphoma)
43004604 (1992)
Acceptable/Guideline
Mouse lymphoma (L5178Y TK[+/-] CHO) cells were exposed to sulfentrazone technical (94.2%) in non-activated dose ranges of 424-1308 ug/mL (Trial 1) and 1308-3000 ug/mL (Trial 2); With S9 activation dose ranges of 424-1407 ug/mL (Trial 1) and 915-1800 ug/mL (Trial 2).
In a forward gene-mutation assay, sulfentrazone at precipitating levels were equivocally positive in the absence of S9 activation.  This response was not repeated at doses up to 1800 g/mL in the presence of S9 activation.
870.5395
Mammalian erythrocyte micronucleus test
43004605 (1992)
Acceptable/Guideline
Groups of 5 male and 5 female ICR mice received single intraperitoneal injection of 85, 170, and 340 mg/kg sulfentrazone technical (94.2%).  Test material was administered in corn oil and bone marrow cells harvested at 24, 48, and 72 hours post-dosing. Cyclophosphamide at 30 mg/kg was used as positive control.
The test was negative in mice administered single intraperitoneal doses of 85-340 mg/kg.  The 340 mg/kg dose was estimated to be approximately 80% of the LD50/7.  No evidence of a cytotoxic effect on the target organ and no significant increase in the frequency of micronucleated polychromatic erythrocytes in bone marrow cells.
870.5450
Dominant lethal
assay - rodent
44248302 (1996)
Acceptable/Guideline
In dominant lethal assay, male rats were dosed at 0, 100, 225, or 450 mg/kg/day for 5 days, and mated to untreated females sequentially for 10 weeks to determine the level of fetal deaths due to dominant lethal mutations.
There were no significant differences from negative controls in the proportion of early dead: total implants, and (total) dead: total implants.  Based on the results, sulfentrazone is considered negative for inducing dominant lethal mutations in pre-meiotic, meiotic, and post-meiotic germ cells of male rats under conditions of this assay up to the estimated maximum tolerable dose (MTD).
870.6200 ACN Study
43345405 (1994)
Acceptable/Guideline
0, 250, 750, & 2000 mg/kg
Systemic Toxicity NOAEL = 250 mg/kg/day.
Systemic Toxicity LOAEL = 750 mg/kg/day, based upon increased incidence of clinical signs, FOB findings, and decreased motor activity which was reversed by day 14 post dose.

No evidence of neuropathology at any dose.
870.6200 SCN Study
43345405 (1994)
Acceptable/Guideline
0, 500, 2500, or 5000 ppm (0/0, 30/37, 150/180, or 265/292 mg/kg/day [M/F])
NOAEL = 500 ppm (30/37 mg/kg/day).
LOAEL = 2500 ppm (150/180 mg/kg/day) based on increased incidence of clinical signs (M&F), decreased BW, BWG, and FC (F), and increased motor activity at week 13 only (F).

No evidence of neuropathology at any dose.
870.7485
Metabolism and
pharmacokinetics
(rat)
43345410 (1994)
Acceptable/Guideline
Phenyl-[14]C sulfentrazone (98% pure.) was administered to Sprague-Dawley rats (five animals/sex/dose) by gavage as a single dose at levels of 50 and 500 mg/kg, or as a single dose of 50 mg/kg following a 14-day pretreatment with non-radioactive sulfentrazone (50 mg/kg/day).
Sulfentrazone was readily absorbed and 84 to 104% of the administered dose was excreted in urine and feces within 72 hours.  There were no major sex differences in the pattern of excretion.  Almost all the radioactivity in the urine was HMS (84-104% of the administered dose).  In the feces, HMS accounted for 1.26-2.55% of the administered dose.  The proposed metabolic pathway appeared to be conversion of the parent compound mainly to HMS (excreted in the urine).  A small amount of HMS was also converted to sulfentrazone 3-carboxylic acid (excreted in the urine and feces).
870.7800 Immunotoxicity (rat)
48748601 (2012)
Acceptable/Guideline
0, 500, 1000, or 2000 ppm (0, 42, 87, or 163 mg/kg/day[F])
Systemic NOAEL = 1000 ppm (87 mg/kg/day).
Systemic LOAEL = 2000 ppm (163 mg/kg/day) based on reduced body weight, and increased absolute and relative spleen weights.
Immunotoxicity NOAEL = 2000 ppm (equivalent to 163 mg/kg/day).
Immunotoxicity LOAEL was not established.
Published literature
47749201 (2009)
De Castro, et al., (2007)
Acceptable/non-guideline
0, 25, or 50 mg/kg bw/day
Dose-dependent, statistically significant delayed ear opening, decreased grip response and rearing frequency, and increased surface righting reflex reaction time observed at >=25 mg/kg/day; no effect on maternal body weight (only parameter tested in dams) during gestation.  The results of this non-guideline study were published in the open literature.  Due to limitations in study conduct and reporting of the statistical analysis, the study is of limited value in risk assessment.

Appendix B.  Methodologies for HEC Calculations.

The RfC methodology applies a dosimetric adjustment that takes into consideration not only the differences in ventilation rate (MV) but also the physicochemical properties of the inhaled compound, the type of toxicity observed (e.g., systemic vs. portal-of-entry) and the pharmacokinetic (PK) but not pharmacodynamic (PD) differences between animals and humans.  Based on the EPA's RfC guidance (1994), the methodology for RfCs derivation is an estimate of the quantitative dose-response assessment of chronic non-cancer toxicity for individual inhaled chemicals and includes dosimetric adjustment to account for the species-specific relationships of exposure concentration to deposited/delivered dose.  This adjustment is influenced by the physicochemical properties of the inhaled compound as well as the type of toxicity observed (e.g., systemic vs. portal-of-entry), and takes into consideration the PK differences between animals and humans.  Though the RfC methodology was developed to estimate toxicity of inhaled chemicals over a lifetime, it can be used for other inhalation exposures (e.g., acute and short-term exposures) since the dosimetric adjustment incorporates mechanistic determinants of disposition that can be applied to shorter duration of exposures provided the assumptions underlying the methodology are still valid.  These assumptions, in turn, vary depending on the type of toxicity observed.  Thus the derivation of a HEC for inhaled gases is described by the following equation:

Where:
PODstudy:  Point of departure identified in the critical toxicology study
Danimal exposure:  Duration of animal exposure (hrs/day; days/wk)
Danticipated exposure:  Anticipated human duration of exposure (hrs/day; days/wk)
RGDR:  Regional Gas Dose Ratio

Calculations used to estimate the inhalation risk to humans from aerosols are dependent not on the RGDR as for gases, but on the regional deposited dose ratio (RDDR).  Inhalation studies using aerosols characterize particulate exposure by defining the particulate diameter (mass median aerodynamic diameter [MMAD]) and the geometric standard deviation (σg), which is then used to determine the RDDR.  The RDDR is a multiplicative factor used to adjust an observed inhalation particulate exposure concentration of an animal (A) to the predicted inhalation particulate exposure concentration for a human (H) that would be associated with the same dose delivered to the rth region or target tissue.

	RDDRr = (RDDr/Normalizing Factor)A
		     (RDDr/Normalizing Factor)H

As with calculations for gases, the r regions and potential target tissues are the three respiratory regions (ET, TB, PU).  The RDDR is easily calculated by using a software program designed specifically for computing the RDDR from the MMAD and σg defined from an aerosol inhalation study.  The values for the species-specific parameters used to calculate the RDDR are provided in the EPA document "Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry."

Regional Deposited Dose Ratio (RDDR) for Sulfentrazone

MMAD  =  2.3
Sigma g  =  2.0

                 	 Body 	         Minute
SPECIES  	 Weight (g)    Ventilation (VE, ml)
-----------------------------------------------------------------------------
    rat          	236          	171.5
  human    	70000         	13800.0
-----------------------------------------------------------------------------
                       Extrathoracic
		 SA (m^2)    	        deposited fraction
--------------------------------------------------------------------------------
    rat                        15     		0.439
  human                   200     		0.341
--------------------------------------------------------------------------------
RATIO                 0.075                     1.288

RDDR = (VE/SA)animal/(VE/SA)human * deposited fractionanimal/deposited fractionhuman
	= (171.5/15)animal/(13800/200)human * 0.439/0.341
	= 0.213

The magnitude of the UFs applied is dependent on the methodology used to calculate risk.  The RfC methodology takes into consideration the PK differences but not the PD differences.  Consequently, the UF for interspecies extrapolation may be reduced to 3X (to account for the PD differences) while the UF for intraspecies variation is retained at 10X.  Thus, the UF when using the RfC methodology is customarily 30X.

B.1.  HEC Calculations for Short- and Intermediate-term Residential Exposure:

Assume residents will be exposed for 24 hrs/day and 7 days/week:

HEC = NOAELstudy * (daily duration of exposureanimal/daily duration of exposurehuman) * (days/week of exposureanimal/days/week of exposurehuman) * RDDR

Residential Handler Outdoor HEC = 0.256 mg/L * 0.213 = 0.054 mg/L
Residential Handler Outdoor HEC = 0.256 mg/L * (5/7) * 0.213 = 0.038 mg/L
Indoor Postapp. Handler Outdoor HEC = 0.256 mg/L * (6/18) * (5/7) * 0.213 = 0.0129 mg/L
Bystander HEC = 0.256 mg/L * (6/24) * (5/7) * 0.213 = 0.00974 mg/L

Table B.1.  HEC Array for Residential Risk Assessment.
                                Relevant Study
                                     LOAEL
                                    (mg/L)
                                     NOAEL
                                    (mg/L)
                                      Da
                                      Dh
                                      Wa
                                      Wh
                                     RDDR
                                  HEC (mg/L)
                                     inter
                                     intra
                                      UF
                    Short-& Intermediate-Term Exposure
                              Inhalation  -  Rat
                            (MRID 49253902) 26-day
                                      ET
                                     1.71
                                     0.256
                       See equations listed above table

                                     0.213
                     Handler/Outdoor Postapp.- 0.054 mg/L
                                       3
                                      10
                                      NA

                          Indoor Posapp.- 0.038 mg/L

              Indoor Postapp. (Adults and Children)- 0.0013 mg/L

                            Bystander- 0.00974 mg/L

Long-Term Exposure:  Not appropriate for sulfentrazone.

Key for Array Tables
LOAEL: Lowest-observed adverse-effect level
NOAEL: No-observed adverse-effect level
Da: Daily animal exposure (hrs/day)
Dh: Anticipated daily human exposure (hrs/day)
Wa: Weekly animal exposure (days/week)
Wh: Anticipated weekly human exposure (days/week)
RRDR: Regional Deposited Dose Ratio
HEC: Human-Equivalent Concentration
inter: Interspecies extrapolation UF
intra: Intraspecies variation UF
UF: Other UF(s)
ET: Extra-thoracic region

Route-to-Route Extrapolation

More information and details in:  Memo, "Route-to-Route Extrapolations" J. Whalen and H. Pettigrew, 10/10/98.

HED's route-to-route extrapolation converts human and animal values from mg/L concentrations to mg/kg oral equivalent doses.  The equation uses a single conversion factor to account for default body weights and respiratory volumes.  An activity factor is used to account for increased exposure resulting from increased respiration.

Using the HEC calculated (based upon terminal airway inflammation in males), a conversion of the inhalation concentration to a dose (mg/L to mg/kg/day) was conducted as follows:
HED (mg/kg/day) = Dose (systemic HEC value, mg/L) x A x CF (L/hr/kg) x D (hours) x AF = mg/kg

Where:
A	=	absorption: ratio of deposition and absorption in respiratory tract compared to
      absorption by the oral route.
CF	=	conversion factor; a L/hr/kg factor which accounts for respiratory volume and body weight for a given species and strain (Table 1 of J. Whalen and H. Pettigrew, 10/10/98).
D	=	duration; duration of daily animal or human exposure (hours).
AF	=	activity factor; animal default is 1.  For humans with a ventilation rate of 16.7 			L/min, the value is 1.2.

Therefore, the residential HED for sulfentrazone is calculated as follows:

Residential Handler and Outdoor Postapplication HED:  (0.05427 mg/L) x 1.2 x 11.8 L/hr/kg x 2 hr x 1 = 1.554 mg/kg/day

B.2.  HEC Calculations for Short- and Intermediate-term Occupational Exposure:
Assume workers will be in the field for 8 hrs/day and 5 days/week:

HEC = NOAELstudy * (daily duration of exposureanimal/daily duration of exposurehuman) * (days/week of exposureanimal/days/week of exposurehuman) * RDDR

HEC = 0.256 mg/L * (6/8) * (5/5) * 0.213 = 0.041 mg/L.

Table B.1.  HEC Array for Occupational Risk Assessment.
                                Relevant Study
                                     LOAEL
                                    (mg/L)
                                     NOAEL
                                    (mg/L)
                                      Da
                                      Dh
                                      Wa
                                      Wh
                                     RDDR
                                  HEC (mg/L)
                                     inter
                                     intra
                                      UF
                    Short-& Intermediate-Term Exposure
                              Inhalation  -  Rat
                            (MRID 49253902) 26-day
                                      ET
                                     1.71
                                     0.256
                                       6
                                       8
                                       5
                                       5
                                     0.213
                                     0.041
                                       3
                                      10
                                      NA
Long-Term Exposure:  Not appropriate for sulfentrazone.

Key for Array Tables
LOAEL: Lowest-observed adverse-effect level
NOAEL: No-observed adverse-effect level
Da: Daily animal exposure (hrs/day)
Dh: Anticipated daily human exposure (hrs/day)
Wa: Weekly animal exposure (days/week)
Wh: Anticipated weekly human exposure (days/week)
RRDR: Regional Deposited Dose Ratio
HEC: Human-Equivalent Concentration
inter: Interspecies extrapolation UF
intra: Intraspecies variation UF
UF: Other UF(s)
ET: Extra-thoracic region

Route-to-Route Extrapolation

More information and details in:  Memo, "Route-to-Route Extrapolations" J. Whalen and H. Pettigrew, 10/10/98.

HED's route-to-route extrapolation converts human and animal values from mg/L concentrations to mg/kg oral-equivalent doses.  The equation uses a single conversion factor to account for default body weights and respiratory volumes.  An activity factor is used to account for increased exposure resulting from increased respiration.

Using the HEC calculated (based upon terminal airway inflammation in males), a conversion of the inhalation concentration to a dose (mg/L to mg/kg/day) was conducted as follows:

HED (mg/kg/day) = Dose (systemic HEC value, mg/L) x A x CF (L/hr/kg) x D (hours) x AF = mg/kg

Where:

A	=	absorption; ratio of deposition and absorption in respiratory tract compared to
      absorption by the oral route.
CF	=	conversion factor; a L/hr/kg factor which accounts for respiratory volume and 			body weight for a given species and strain (Table 1 of J. Whalen and H. 				Pettigrew, 10/10/98).
D	=	duration; duration of daily animal or human exposure (hours).
AF	=	activity factor; animal default is 1.  For humans, the value varies with ventilation 			rates determined by occupational/restidential scientists; 0.6 (8.3L/min), 1.2 (16.7 			L/min) and 2.1 (29 L/min)

Therefore, the occupational HED for sulfentrazone is calculated as follows:

Occupational HED, Ventilation Rate, 8.3 L/min:  (0.0407 mg/L) x 1 x 0.6 x 11.8 L/hr/kg x 8 hr = 2.317 mg/kg/day
Occupational HED, Ventilation Rate, 16.7 L/min:  0.0407 mg/L) x 1 x 1.2 x 11.8L/hr/kg x 8 hr = 4.661 mg/kg/day
Occupational HED, Ventilation Rate, 29 L/min:  (0.0407 mg/L) x 1 x 2.1 x 11.8 L/hr/kg x 8 hr = 8.094 mg/kg/day

Based on the current sulfentrazone label, HED believes exposures can be short- (1-30 days) or intermediate- (1 to 6 months) term in duration.  Long-term exposures are not anticipated for sulfentrazone based on proposed labeled uses.  For the short- and intermediate-term scenarios, inhalation data from the 26-day inhalation rodent study was most appropriate for determining HECs.  In the RfC methodology, different HECs may be calculated for the same experimental NOAEL due to the following:

1. Different algorithms are used to derive HECs for systemic versus portal-of-entry effects.  Typically, HECs are calculated separately for systemic versus portal-of-entry effect.  For sulfentrazone, portal-of-entry irritation was observed and, therefore, only portal-of-entry HECs were derived.
2. Time adjustments are traditionally needed for non-occupational (bystander) versus occupational exposure scenarios.  Traditionally, HECs for non-occupational exposure are based on the number of hours an individual may be at home.  Therefore, the most conservative estimate of hours spent at home would be 24 hours/day and 7 days/week.  In comparison, the average workweek for an occupational worker is 8 hours/day and 5 days/week.  The HEC array table reflects the time adjustment in the calculations.

Appendix C.  Physical/Chemical Properties

Table B.1.  Physicochemical Properties of Technical Grade Sulfentrazone.
Parameter
Value
Reference
Melting range
120-122 ºC
DP# 288712, 3/6/03, G. Kramer, G. Reddy, and L. Liu
pH
4.78 at 23 ºC

Density
0.53 g/cm[3]

Water solubility
4.0 x 10[2] ug/g

Solvent solubility
18.6% w/w in acetonitrile

Vapor pressure
8 x 10[-10] mm Hg

Dissociation constant, pKa
6.56

Octanol/water partition coefficient, Log(KOW)
1.49 at pH 5

UV/visible absorption spectrum
Not available

Appendix D.  International Residue Limits

                       Sulfentrazone (129081; 4/15/2014)
Summary of US and International Tolerances and Maximum Residue Limits
Residue Definition:
US
Canada
Mexico[1]
Codex
40 CFR §180.498
(a)(1) General: Compliance with the tolerance levels specified below is to be determined by measuring only the sum of sulfentrazone (N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide) and its metabolite HMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide, calculated as the stoichiometric equivalent of sulfentrazone
N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-phenyl]methanesulfonamide, including the metabolite N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide

None
Commodity
                Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US
Canada
Mexico[1]
Codex
Soybean, seed
0.05
0.05 dry soybeans

(2)Compliance with the tolerance levels specified below is to be determined by measuring only the sum of sulfentrazone (N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide) and its metabolites HMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide) and DMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide, calculated as the stoichiometric equivalent of sulfentrazone
N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-phenyl]methanesulfonamide, including the metabolites N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide and N-[2,4-dichloro-5-4-(difluoromethyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide

None
Commodity
Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US
Canada
Mexico[1]
Codex
Asparagus
0.15
0.15

Berry and small fruit, group 13-07
0.15

Brassica, head and stem, subgroup 5A
0.20
0.2 cabbages

Brassica, leafy greens, subgroup 5B
0.40

Corn, field, forage
0.20

Corn, field, grain
0.15

Corn, field, stover
0.30

Flax
0.15
0.15 flaxseeds

Fruit, citrus, group 10-10
0.15

Horseradish
0.20
0.2 horseradish roots

Melon, subgroup 9A
0.15

Nut, tree, group 14
0.15

Pea and bean, dried shelled, except soybean, subgroup 6C
0.15
0.15 Dry (adzuki beans, beans, black-eyed peas, broad beans, catjang seeds, chickpeas, cowpea seed, field peas, grain lupin, guar seeds, kidney beans, lablab beans, lentils, lima beans, moth beans, mung beans, navy beans, pigeon peas, pink beans, pinto beans, rice beans, southern peas, tepary beans, urd beans)

Pea, succulent
0.15

Peanut
0.20

Peanut, meal
0.40

Peppermint, tops
0.30
0.3

Pistachio
0.15

Rhubarb
0.15

Spearmint, tops
0.30
0.3

Sugarcane, cane
0.15

Sugarcane, molasses
0.20

Sunflower subgroup 20B
0.20
0.2 sunflower seeds

Turnip, roots
0.15

Turnip, tops
0.60

Vegetable, fruiting, group 8-10
0.15

Vegetable, soybean, succulent
0.15

Vegetable, tuberous and corm, subgroup 1C
0.15

US
Canada
Mexico[1]
Codex
(c) Compliance with the tolerance levels specified below is to be determined by measuring only the sum of sulfentrazone (N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide) and its metabolites HMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide) and DMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide, calculated as the stoichiometric equivalent of sulfentrazone in or on the following commodities

                                     None
Commodity
Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US
Canada
Mexico[1]
Codex
Bean, lima, succulent
0.15

Cowpea, succulent
0.15

Wheat, forage
0.50

Wheat, grain
0.15
0.15 grain, cereal, group 15, except sweet corn; bran

Wheat, hay
0.30

Wheat, straw
1.5

US
Canada
Mexico[1]
Codex
 (d) Indirect or inadvertent residues. Compliance with the tolerance levels specified below is to be determined by measuring only the sum of sulfentrazone (N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide) and its metabolites HMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide) and DMS (N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide, calculated as the stoichiometric equivalent of sulfentrazone

                                     None
Commodity
Tolerance (ppm) /Maximum Residue Limit (mg/kg)

US
Canada
Mexico[1]
Codex
Grain, cereal (excluding sweet corn), Hulls
0.30

Grain, cereal, forage, fodder and straw, group 16, except sweet corn; forage
0.2

Grain, cereal, forage, fodder and straw, group 16, except sweet corn; hay
0.2

Grain, cereal, forage, fodder and straw, group 16, except sweet corn; stover
0.1

Grain, cereal, forage, fodder and straw, group 16, except sweet corn; straw
0.6

Grain, cereal, group 15, except sweet corn
0.1

Grain, cereal, group 15, except sweet corn; bran
0.15

Completed:  M. Negussie; 04/16/14
1 Mexico adopts U.S. tolerances and/or Codex MRLs for its export purposes.


[Federal Register Volume 88, Number 100 (Wednesday, May 24, 2023)]
[Notices]
[Pages 33659-33660]
[FR Doc No: 2023-10993]

=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

[Docket No. FAA-2023-1169]

Agency Information Collection Activities: Requests for Comments;
Clearance of New Approval of Information Collection: Inflation
Reduction Act Fueling Aviation's Sustainable Transition Grant Program

AGENCY: Federal Aviation Administration (FAA), DOT.

ACTION: Notice and request for comments.

-----------------------------------------------------------------------

SUMMARY: In accordance with the Paperwork Reduction Act of 1995, FAA
invites public comments about our intention to request Office of
Management and Budget (OMB) approval for a new information collection.
The collection involves soliciting project proposals for the Inflation
Reduction Act (IRA) Fueling Aviation's Sustainable Transition (FAST)
Grant Program. The information to be collected will be used to
determine projects to be awarded FAST competitive discretionary grants.

DATES: Written comments should be submitted by July 24, 2023.

ADDRESSES: Please send written comments:
    By Electronic Docket: www.regulations.gov (Enter docket number into
search field).
    By mail: Federal Aviation Administration, Attn: Anna Oldani (AEE-
500), 800 Independence Ave. SW, Washington, DC 20591.

FOR FURTHER INFORMATION CONTACT: Chris Dorbian by email at:
[email protected]; phone:<PHONE_NUMBER>.

SUPPLEMENTARY INFORMATION:
    Public Comments Invited: You are asked to comment on any aspect of
this information collection, including (a) Whether the proposed
collection of information is necessary for FAA's performance; (b) the
accuracy of the estimated burden; (c) ways for FAA to enhance the
quality, utility and clarity of the information collection; and (d)
ways that the burden could be minimized without reducing the quality of
the collected information. The agency will summarize and/or include
your comments in the request for OMB's clearance of this information
collection.
    OMB Control Number: 2120-XXXX.
    Title: Inflation Reduction Act Fueling Aviation's Sustainable
Transition Grant Program.
    Form Numbers: Not applicable.
    Type of Review: New information collection.
    Background: The FAA is using this collection to solicit the
information necessary to evaluate and select sustainable aviation fuel
and low-emission aviation technology projects for funding under the
Inflation Reduction Act (IRA), signed on August 16, 2022. Section 40007
of the Inflation Reduction Act of 2022 directs the Secretary of
Transportation to implement a ``competitive grant program for eligible
entities to carry out projects located in the United States that
produce, transport, blend, or store sustainable aviation fuel, or
develop, demonstrate, or apply low-emission aviation technologies.''
The Department of Transportation (DOT), Federal Aviation Administration
(FAA) is seeking to establish this new grant program--named the Fueling
Aviation's Sustainable Transition (FAST) Grant Program--and collect
project proposals via a Notice of Funding Opportunity (NOFO). FAST will
have elements focused on sustainable aviation fuel (SAF), to be termed
FAST-SAF, and elements focused on low-emission aviation technologies,
to be termed FAST-Tech. The program aims to reduce the greenhouse gas
emissions (GHG) associated with the aviation sector, in line with the
net-zero GHG by 2050 goal outlined in the U.S. Aviation Climate Action
Plan. The amount of available funding for the two programs is $244.53M
and $46.53M for FAST-SAF and FAST-Tech, respectively.
    The NOFO will solicit project proposals from eligible entities. The
collected information is required for FAA to evaluate proposals and
distribute IRA funds to address U.S. climate goals. Eligible entities
who elect to compete for funding and obtain benefits from the FAST
Grant Program will submit project information. The information
collected is based on grant criteria outlined in the IRA Section 40007.
    The FAA will use information submitted to evaluate and select
projects for funding that most closely align with the criteria outlined
in the NOFO. A team of subject matter experts in aircraft technology
development and sustainable aviation fuels from the FAA and other
government agencies will assess each application against the applicable
criteria. The information FAA is collecting will include technical,
project management, and cost proposals for candidate projects. Key
evaluation criteria include the capacity for the project to increase
the domestic production and deployment of SAF or the use of low-
emission aviation technologies and the projected greenhouse gas
emissions from such a project.
    Project information will be solicited through a NOFO published to
grants.gov. Applications will be collected via grants.gov. The NOFO
will outline in detail the form of the full application.
    Respondents: Eligible entities as outlined in IRA Section 40007.
    Frequency: One-time application per phase of funding.
    Estimated Average Burden per Response: Approximately 500 hours.
    Estimated Total Annual Burden: Approximately 25,000 hours (assuming
50 applicants).

    Issued in Washington, DC, on May 18, 2023.
Kevin Welsh,
Executive Director, Federal Aviation Administration--Office of
Environment and Energy.
[FR Doc. 2023-10993 Filed 5-23-23; 8:45 am]
BILLING CODE 4910-13-P