95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000005 0.82 0.000032 4.98 0.000337 51.89 All infants: 0.000003 0.42 0.000040 6.13 0.000433 66.54 Children 1 2 yrs: 0.000013 2.03 0.000056 8.69 0.000755 116.10 Children 3 5 yrs: 0.000012 1.90 0.000043 6.68 0.000597 91.88 Children 6 12 yrs: 0.000008 1.24 0.000031 4.85 0.000452 69.48 Youth 13 19 yrs: 0.000005 0.84 0.000023 3.61 0.000300 46.09 Adults 20 49 yrs: 0.000004 0.64 0.000024 3.75 0.000283 43.61 Adults 50+ yrs: 0.000003 0.48 0.000042 6.50 0.000307 47.18 Females 13 49 yrs: 0.000003 0.52 0.000022 3.40 0.000270 41.51 Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm.

Summary of Residue Distribution Files ( RDF)

RDF File N residues N residues N LODs LOD N Zeros # Name w freq's w/ o freq's Value

1 31GFctfsn. rdf 0 16 0 0 197 2 32GFctpsn. rdf 0 16 0 0 146 3 38LEctsn. rdf 0 16 0 0 1762 4 37LIctsn. rdf 0 16 0 0 746 5 20OGctsn. rdf 0 16 0 0 383 6 1Pecanft. rdf 5 10 0 0 253 7 49POmnfr. rdf 11 59 0 0 3040 8 50POmppr. rdf 3 10 0 0 1083 9 57SWmssp. rdf 11 59 0 0 272 10 58SWmcsp. rdf 3 10 0 0 582 Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm.

Analysis 11: Summary of Orange and Grapefruit Residue Inputs for Aldicarb Acute Dietary Exposure Excludes Potatoes [ Sensitivity Analysis  Assumes Aldicarb per se = 0 ppm in Citrus;

Assumes 2 LOD Residues in Citrus Monitoring Samples were True Zeroes]

Commodity1 Food Form ( FF) 2 Classifi cation3 F/

P4 % CT ( A/ M) 5 Data Source6 Acute RDF ( RDF #) 7 Uncooked PB F Cooked ( NFS) PB F 7/ 13 CTF  single oranges 16 Det.+ 383Z ( 20)

Canned ( NFS) PB P Oranges

Juice Frozen ( NFS) PB P 11/ 23 CTF  single oranges 16 Det.+ 383Z ( 20)

Oranges

Juice Conc. All 7 food forms PB P 11/ 23 CTF  single oranges 16 Det.+ 383Z ( 20)

Uncooked PB F Cooked ( NFS) PB F Boiled PB F 7/ 13 CTF  single oranges 16 Det.+ 383Z ( 20)

Canned ( NFS) PB P Oranges

Peel Frozen ( NFS) PB P 11/ 23 CTF  single oranges 16 Det.+ 383Z ( 20)

Uncooked NB F Cooked ( NFS) NB F 7/ 13 CTF  single oranges 16 Det.+ 383Z ( 20)

Oranges

Peeled Fruit Canned ( NFS) PB P 11/ 23 CTF  single oranges 16 Det.+ 383Z ( 20) Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm.

Analysis 11: Summary of Orange and Grapefruit Residue Inputs for Aldicarb Acute Dietary Exposure Excludes Potatoes [ Sensitivity Analysis  Assumes Aldicarb per se = 0 ppm in Citrus;

Assumes 2 LOD Residues in Citrus Monitoring Samples were True Zeroes]

Commodity1 Food Form ( FF) 2 Classifi cation3 F/

P4 % CT ( A/ M) 5 Data Source6 Acute RDF ( RDF #) 7 Uncooked PB F Boiled PB F 16/ 25 CTF  single oranges 16 Det.+ 197Z ( 31)

Canned ( NFS) PB P Grapefruit

Juice Frozen PB P 17/ 33 CTF  single oranges 16 Det.+ 146Z ( 32)

Grapefruit

Juice Conc. Frozen ( NFS) PB P 17/ 33 CTF  single oranges 16 Det.+ 146Z ( 32)

Grapefruit

Peel Peel PB F 16/ 25 CTF  single oranges 16 Det.+ 197Z ( 31)

Uncooked NB F Cooked ( NFS) NB F Boiled NB F 16/ 25 CTF  single oranges 16 Det.+ 197Z ( 31)

Grapefruit

Peeled Fruit Canned ( NFS) PB P 17/ 33 CTF  single oranges 16 Det.+ 146Z ( 32)

1 The reassessed tolerances are: 0.3 ppm in orange and grapefruit; and 0.2 ppm in potatoes.

2 Food forms shown in the table are taken directly from the DEEM software.

3 Refer to HED SOP99.6. NB = Not Blended; PB = Partially Blended; B = Blended.

4 F = Fresh commodity; P = Processed commodity.

5 BEAD estimated percent crop treated; M = estimated Maximum ( for acute exposure).

6 CTF = Carbamate Task Force.

7 RDF = Residue Distribution File. Det. = detect; LOD = residues at 2 LOD; Z = zeroes. Numbered RDFs are shown in detail in Attachment 4. For dried potatoes, a point estimate AR was used.

[ Refer to Table 7 for the Remaining Residue Inputs] Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm, and Excluding Potato Commodities.

Page 180 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB Residue file name: C:\$ MyFiles\ Aldicarb Dietary\ dietary Apr 2006\ ER no potatos aldicarb + citrus nondects zero 15. R98 Analysis Date 04 19 2006 Residue file dated: 04 19 2006/ 16: 43: 27/ 8 Reference dose ( aRfD) = 0.0005 mg/ kg bw/ day  RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter # 1 Param # 2 Param # 3 Comment # Code       1 6 31GFctfsn. rdf 2 6 32GFctpsn. rdf 3 6 38LEctsn. rdf 4 6 37LIctsn. rdf 5 6 20OGctsn. rdf 6 6 1Pecanft. rdf 7 6 49POmnfr. rdf 8 6 50POmppr. rdf 9 6 57SWmssp. rdf 10 6 58SWmcsp. rdf EPA Crop Food Name Def Res Adj. Factors RDL Code Grp ( ppm) # 1 # 2 Pntr        06030300 6C Bean, black, seed 0.000200 0.050 1.000 06030320 6C Bean, broad, seed 0.000200 0.050 1.000 06030340 6C Bean, cowpea, seed 0.000200 0.050 1.000 06030350 6C Bean, great northern, seed 0.000200 0.050 1.000 06030360 6C Bean, kidney, seed 0.000200 0.050 1.000 06030380 6C Bean, lima, seed 0.000200 0.050 1.000 06030390 6C Bean, mung, seed 0.000200 0.050 1.000 06030400 6C Bean, navy, seed 0.000200 0.050 1.000 06030410 6C Bean, pink, seed 0.000200 0.050 1.000 06030420 6C Bean, pinto, seed 0.000200 0.050 1.000 06030980 6C Chickpea, seed 0.000200 0.050 1.000 06030981 6C Chickpea, seed babyfood 0.000200 0.050 1.000 06030990 6C Chickpea, flour 0.000200 0.050 1.000 95001150 O Coffee, roasted bean 0.002000 1.000 1.000 95001160 O Coffee, instant 0.002000 1.000 1.000 95001280 O Cottonseed, oil 0.000495 1.000 1.000 95001281 O Cottonseed, oil babyfood 0.000495 1.000 1.000 10001800 10 Grapefruit 110 Uncooked; Fresh or N/ S; Cook Meth N/ S 0.000747 1.000 1.000 1 210 Cooked; Fresh or N/ S; Cook Meth N/ S 0.000747 1.000 1.000 1 240 Cooked; Canned; Cook Meth N/ S 0.000922 1.000 1.000 2 10001810 10 Grapefruit, juice 110 Uncooked; Fresh or N/ S; Cook Meth N/ S 0.000747 0.014 1.000 1 120 Uncooked; Frozen; Cook Meth N/ S 0.000922 0.014 1.000 2 130 Uncooked; Dried; Cook Meth N/ S 0.000747 0.014 1.000 1 211 Cooked; Fresh or N/ S; Baked 0.000747 0.014 1.000 1 240 Cooked; Canned; Cook Meth N/ S 0.000922 0.014 1.000 2 06031820 6C Guar, seed 0.000200 1.000 1.000 06031821 6C Guar, seed babyfood 0.000200 1.000 1.000 10001990 10 Lemon 0.000074 1.000 1.000 3 Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm, and Excluding Potato Commodities.

Page 181 of 203 10002000 10 Lemon, juice 0.000074 0.460 1.000 3 10002001 10 Lemon, juice babyfood 0.000074 0.460 1.000 3 10002010 10 Lemon, peel 0.000074 1.000 1.000 3 06032030 6C Lentil, seed 0.000200 1.000 1.000 10002060 10 Lime 0.000200 1.000 1.000 4 10002070 10 Lime, juice 0.000200 0.460 1.000 4 10002071 10 Lime, juice babyfood 0.000200 0.460 1.000 4 10002400 10 Orange 110 Uncooked; Fresh or N/ S; Cook Meth N/ S 0.000374 1.000 1.000 5 210 Cooked; Fresh or N/ S; Cook Meth N/ S 0.000374 1.000 1.000 5 240 Cooked; Canned; Cook Meth N/ S 0.000440 1.000 1.000 5 10002410 10 Orange, juice 110 Uncooked; Fresh or N/ S; Cook Meth N/ S 0.000374 0.580 1.000 5 120 Uncooked; Frozen; Cook Meth N/ S 0.000440 0.580 1.000 5 130 Uncooked; Dried; Cook Meth N/ S 0.000374 0.580 1.000 5 210 Cooked; Fresh or N/ S; Cook Meth N/ S 0.000374 0.580 1.000 5 211 Cooked; Fresh or N/ S; Baked 0.000374 0.580 1.000 5 212 Cooked; Fresh or N/ S; Boiled 0.000374 0.580 1.000 5 221 Cooked; Frozen; Baked 0.000440 0.580 1.000 5 240 Cooked; Canned; Cook Meth N/ S 0.000440 0.580 1.000 5 10002411 10 Orange, juice babyfood 240 Cooked; Canned; Cook Meth N/ S 0.000440 0.580 1.000 5 10002420 10 Orange, peel 110 Uncooked; Fresh or N/ S; Cook Meth N/ S 0.000374 1.000 1.000 5 210 Cooked; Fresh or N/ S; Cook Meth N/ S 0.000374 1.000 1.000 5 211 Cooked; Fresh or N/ S; Baked 0.000374 1.000 1.000 5 212 Cooked; Fresh or N/ S; Boiled 0.000374 1.000 1.000 5 240 Cooked; Canned; Cook Meth N/ S 0.000440 1.000 1.000 5 06032560 6C Pea, dry 0.000200 1.000 1.000 06032561 6C Pea, dry babyfood 0.000200 1.000 1.000 06032580 6C Pea, pigeon, seed 0.000200 1.000 1.000 95002630 O Peanut 0.002585 1.000 1.000 95002640 O Peanut, butter 0.002585 1.890 1.000 95002650 O Peanut, oil 0.000705 1.000 1.000 14002690 14 Pecan 0.614000 1.000 1.000 6 06003470 6 Soybean, seed 0.000100 1.000 1.000 06003480 6 Soybean, flour 0.000100 1.000 1.000 06003481 6 Soybean, flour babyfood 0.000100 1.000 1.000 06003490 6 Soybean, soy milk 0.000100 1.000 1.000 06003491 6 Soybean, soy milk babyfood or in 0.000100 1.000 1.000 06003500 6 Soybean, oil 0.000050 1.000 1.000 06003501 6 Soybean, oil babyfood 0.000050 1.000 1.000 Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm, and Excluding Potato Commodities.

Page 182 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ( 1994 98 data) Residue file: ER no potatos aldicarb + citrus nondects zero 15. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 19 2006/ 18: 53: 15 Residue file dated: 04 19 2006/ 16: 43: 27/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: RAT RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000003 0.54 0.000009 1.81 0.000063 12.62 All infants: 0.000000 0.08 0.000002 0.49 0.000025 5.03 Children 1 2 yrs: 0.000007 1.50 0.000022 4.38 0.000199 39.73 Children 3 5 yrs: 0.000008 1.69 0.000020 4.05 0.000162 32.48 Children 6 12 yrs: 0.000005 1.02 0.000013 2.57 0.000101 20.21 Youth 13 19 yrs: 0.000002 0.36 0.000007 1.44 0.000067 13.46 Adults 20 49 yrs: 0.000002 0.37 0.000006 1.16 0.000050 10.02 Adults 50+ yrs: 0.000002 0.37 0.000006 1.28 0.000052 10.32 Females 13 49 yrs: 0.000002 0.33 0.000005 1.05 0.000055 10.96 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ( 1994 98 data) Residue file: ER no potatos aldicarb + citrus nondects zero 15. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 20 2006/ 13: 59: 20 Residue file dated: 04 19 2006/ 17: 00: 27/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: RAT Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000003 0.36 0.000009 1.21 0.000063 8.42 All infants: 0.000000 0.05 0.000002 0.32 0.000025 3.35 Children 1 2 yrs: 0.000007 1.00 0.000022 2.92 0.000199 26.49 Children 3 5 yrs: 0.000008 1.13 0.000020 2.70 0.000162 21.65 Children 6 12 yrs: 0.000005 0.68 0.000013 1.71 0.000101 13.47 Youth 13 19 yrs: 0.000002 0.24 0.000007 0.96 0.000067 8.98 Adults 20 49 yrs: 0.000002 0.25 0.000006 0.78 0.000050 6.68 Adults 50+ yrs: 0.000002 0.25 0.000006 0.85 0.000052 6.88 Females 13 49 yrs: 0.000002 0.22 0.000005 0.70 0.000055 7.31 Attachment 15: Analysis 11  Residue Inputs and DEEMJ Files for Acute Exposure Assessment, Assuming Aldicarb per se = 0 ppm and Assuming Citrus Nondetects = 0 ppm, and Excluding Potato Commodities.

Page 183 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ( 1994 98 data) Residue file: ER no potatos aldicarb + citrus nondects zero 15. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 20 2006/ 16: 01: 34 Residue file dated: 04 19 2006/ 16: 53: 01/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000003 0.42 0.000009 1.39 0.000063 9.71 All infants: 0.000000 0.06 0.000002 0.37 0.000025 3.87 Children 1 2 yrs: 0.000007 1.15 0.000022 3.37 0.000199 30.56 Children 3 5 yrs: 0.000008 1.30 0.000020 3.12 0.000162 24.98 Children 6 12 yrs: 0.000005 0.78 0.000013 1.97 0.000101 15.55 Youth 13 19 yrs: 0.000002 0.28 0.000007 1.11 0.000067 10.36 Adults 20 49 yrs: 0.000002 0.29 0.000006 0.90 0.000050 7.71 Adults 50+ yrs: 0.000002 0.29 0.000006 0.98 0.000052 7.94 Females 13 49 yrs: 0.000002 0.25 0.000005 0.81 0.000055 8.43 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 184 of 203 Surface Water  MS Cotton U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB MS COTTON Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ Water MS cotton. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 16: 21/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter # 1 Param # 2 Param # 3 Comment # Code       1 6 MScotton TS. rdf EPA Crop Food Name Def Res Adj. Factors RDL Code Grp ( ppm) # 1 # 2 Pntr        86010000 O Water, direct, all sources 1.000000 1.000 1.000 1 86020000 O Water, indirect, all sources 1.000000 1.000 1.000 1 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB MS COTTON ( 1994 98 data) Residue file: Water MS cotton. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 13: 08: 37 Residue file dated: 04 26 2006/ 10: 16: 21/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000025 5.04 0.000160 31.91 0.000642 128.49 All infants: 0.000078 15.54 0.000557 111.40 0.002292 458.31 Children 1 2 yrs: 0.000037 7.45 0.000240 48.07 0.000970 193.99 Children 3 5 yrs: 0.000035 7.06 0.000224 44.83 0.000903 180.67 Children 6 12 yrs: 0.000024 4.86 0.000154 30.76 0.000627 125.33 Youth 13 19 yrs: 0.000018 3.50 0.000115 22.97 0.000488 97.56 Adults 20 49 yrs: 0.000024 4.76 0.000150 29.99 0.000589 117.90 Adults 50+ yrs: 0.000027 5.32 0.000161 32.24 0.000569 113.82 Females 13 49 yrs: 0.000024 4.72 0.000150 30.07 0.000591 118.20 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 185 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB MS COTTON ( 1994 98 data) Residue file: Water MS cotton. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 13: 20: 19 Residue file dated: 04 26 2006/ 10: 16: 21/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000025 3.36 0.000160 21.28 0.000642 85.66 All infants: 0.000078 10.36 0.000557 74.27 0.002292 305.54 Children 1 2 yrs: 0.000037 4.96 0.000240 32.05 0.000970 129.33 Children 3 5 yrs: 0.000035 4.70 0.000224 29.89 0.000903 120.44 Children 6 12 yrs: 0.000024 3.24 0.000154 20.51 0.000627 83.56 Youth 13 19 yrs: 0.000018 2.34 0.000115 15.31 0.000488 65.04 Adults 20 49 yrs: 0.000024 3.17 0.000150 20.00 0.000589 78.60 Adults 50+ yrs: 0.000027 3.55 0.000161 21.49 0.000569 75.88 Females 13 49 yrs: 0.000024 3.15 0.000150 20.05 0.000591 78.80 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB MS COTTON ( 1994 98 data) Residue file: Water MS cotton. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 13: 14: 03 Residue file dated: 04 26 2006/ 10: 16: 21/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000025 3.88 0.000160 24.55 0.000642 98.84 All infants: 0.000078 11.95 0.000557 85.69 0.002292 352.54 Children 1 2 yrs: 0.000037 5.73 0.000240 36.98 0.000970 149.23 Children 3 5 yrs: 0.000035 5.43 0.000224 34.48 0.000903 138.97 Children 6 12 yrs: 0.000024 3.73 0.000154 23.67 0.000627 96.41 Youth 13 19 yrs: 0.000018 2.70 0.000115 17.67 0.000488 75.05 Adults 20 49 yrs: 0.000024 3.66 0.000150 23.07 0.000589 90.69 Adults 50+ yrs: 0.000027 4.09 0.000161 24.80 0.000569 87.56 Females 13 49 yrs: 0.000024 3.63 0.000150 23.13 0.000591 90.92 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 186 of 203 Surface Water  FL Citrus U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB FL CITRUS Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ Water FL citrus. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 15: 14/ 8 Reference dose ( aRfD) = 0.0005 mg/ kg bw/ day  RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter # 1 Param # 2 Param # 3 Comment # Code       1 6 FL Citrus. rdf EPA Crop Food Name Def Res Adj. Factors RDL Code Grp ( ppm) # 1 # 2 Pntr        86010000 O Water, direct, all sources 1.000000 1.000 1.000 1 86020000 O Water, indirect, all sources 1.000000 1.000 1.000 1 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL CITRUS ( 1994 98 data) Residue file: Water FL citrus. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 49: 45 Residue file dated: 04 26 2006/ 10: 15: 14/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000006 1.15 0.000045 9.05 0.000233 46.51 All infants: 0.000015 3.09 0.000152 30.44 0.000850 170.01 Children 1 2 yrs: 0.000008 1.64 0.000068 13.59 0.000360 71.95 Children 3 5 yrs: 0.000008 1.59 0.000064 12.72 0.000329 65.84 Children 6 12 yrs: 0.000005 1.08 0.000044 8.76 0.000226 45.29 Youth 13 19 yrs: 0.000004 0.75 0.000032 6.46 0.000175 35.00 Adults 20 49 yrs: 0.000005 1.09 0.000043 8.51 0.000216 43.25 Adults 50+ yrs: 0.000006 1.28 0.000046 9.14 0.000215 42.95 Females 13 49 yrs: 0.000005 1.07 0.000042 8.45 0.000217 43.31 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 187 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL CITRUS ( 1994 98 data) Residue file: Water FL citrus. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 56: 42 Residue file dated: 04 26 2006/ 10: 15: 14/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000006 0.77 0.000045 6.04 0.000233 31.01 All infants: 0.000015 2.06 0.000152 20.29 0.000850 113.34 Children 1 2 yrs: 0.000008 1.09 0.000068 9.06 0.000360 47.97 Children 3 5 yrs: 0.000008 1.06 0.000064 8.48 0.000329 43.89 Children 6 12 yrs: 0.000005 0.72 0.000044 5.84 0.000226 30.19 Youth 13 19 yrs: 0.000004 0.50 0.000032 4.31 0.000175 23.33 Adults 20 49 yrs: 0.000005 0.73 0.000043 5.67 0.000216 28.83 Adults 50+ yrs: 0.000006 0.86 0.000046 6.09 0.000215 28.63 Females 13 49 yrs: 0.000005 0.72 0.000042 5.63 0.000217 28.88 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL CITRUS ( 1994 98 data) Residue file: Water FL citrus. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 11: 04: 02 Residue file dated: 04 26 2006/ 10: 15: 14/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000006 0.89 0.000045 6.96 0.000233 35.78 All infants: 0.000015 2.38 0.000152 23.41 0.000850 130.77 Children 1 2 yrs: 0.000008 1.26 0.000068 10.45 0.000360 55.35 Children 3 5 yrs: 0.000008 1.22 0.000064 9.79 0.000329 50.64 Children 6 12 yrs: 0.000005 0.83 0.000044 6.74 0.000226 34.84 Youth 13 19 yrs: 0.000004 0.58 0.000032 4.97 0.000175 26.92 Adults 20 49 yrs: 0.000005 0.84 0.000043 6.55 0.000216 33.27 Adults 50+ yrs: 0.000006 0.99 0.000046 7.03 0.000215 33.04 Females 13 49 yrs: 0.000005 0.83 0.000042 6.50 0.000217 33.32 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 188 of 203 Surface Water  ID Potato U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB ID POTATO Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ Water ID potato. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 15: 42/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  RDL indices and parameters for Monte Carlo Analysis: Index Dist Parameter # 1 Param # 2 Param # 3 Comment # Code       1 6 ID Potato. rdf EPA Crop Food Name Def Res Adj. Factors RDL Code Grp ( ppm) # 1 # 2 Pntr        86010000 O Water, direct, all sources 1.000000 1.000 1.000 1 86020000 O Water, indirect, all sources 1.000000 1.000 1.000 1 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID POTATO ( 1994 98 data) Residue file: Water ID potato. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 11: 14: 26 Residue file dated: 04 26 2006/ 10: 15: 42/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000002 0.46 0.000022 4.49 0.000119 23.84 All infants: 0.000006 1.25 0.000072 14.47 0.000441 88.16 Children 1 2 yrs: 0.000003 0.66 0.000033 6.70 0.000186 37.26 Children 3 5 yrs: 0.000003 0.64 0.000032 6.30 0.000170 34.07 Children 6 12 yrs: 0.000002 0.44 0.000021 4.26 0.000117 23.50 Youth 13 19 yrs: 0.000002 0.30 0.000016 3.18 0.000090 18.08 Adults 20 49 yrs: 0.000002 0.43 0.000021 4.22 0.000111 22.20 Adults 50+ yrs: 0.000003 0.51 0.000023 4.64 0.000110 21.92 Females 13 49 yrs: 0.000002 0.43 0.000021 4.22 0.000113 22.59 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 189 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID POTATO ( 1994 98 data) Residue file: Water ID potato. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 11: 32: 33 Residue file dated: 04 26 2006/ 10: 15: 42/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000002 0.31 0.000022 2.99 0.000119 15.89 All infants: 0.000006 0.83 0.000072 9.64 0.000441 58.77 Children 1 2 yrs: 0.000003 0.44 0.000033 4.46 0.000186 24.84 Children 3 5 yrs: 0.000003 0.43 0.000032 4.20 0.000170 22.71 Children 6 12 yrs: 0.000002 0.29 0.000021 2.84 0.000117 15.66 Youth 13 19 yrs: 0.000002 0.20 0.000016 2.12 0.000090 12.06 Adults 20 49 yrs: 0.000002 0.29 0.000021 2.81 0.000111 14.80 Adults 50+ yrs: 0.000003 0.34 0.000023 3.09 0.000110 14.62 Females 13 49 yrs: 0.000002 0.29 0.000021 2.81 0.000113 15.06 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID POTATO ( 1994 98 data) Residue file: Water ID potato. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 11: 20: 48 Residue file dated: 04 26 2006/ 10: 15: 42/ 8 Daily totals for food and foodform consumption used. MC iterations = 1000 MC list in residue file MC seed = 10 Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000002 0.35 0.000022 3.45 0.000119 18.34 All infants: 0.000006 0.96 0.000072 11.13 0.000441 67.81 Children 1 2 yrs: 0.000003 0.51 0.000033 5.15 0.000186 28.66 Children 3 5 yrs: 0.000003 0.49 0.000032 4.85 0.000170 26.21 Children 6 12 yrs: 0.000002 0.34 0.000021 3.28 0.000117 18.07 Youth 13 19 yrs: 0.000002 0.23 0.000016 2.45 0.000090 13.91 Adults 20 49 yrs: 0.000002 0.33 0.000021 3.25 0.000111 17.08 Adults 50+ yrs: 0.000003 0.39 0.000023 3.57 0.000110 16.86 Females 13 49 yrs: 0.000002 0.33 0.000021 3.24 0.000113 17.38 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 190 of 203 Groundwater  AL U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB AL GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW AL. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 11: 34/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.020000 1.000 1.000 86020000 O Water, indirect, all sources 0.020000 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB AL GROUNDWATER ( 1994 98 data) Residue file: GW AL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 20: 06 Residue file dated: 04 26 2006/ 10: 11: 34/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001045 139.30 0.001962 261.65 0.003926 523.51 All infants: 0.003939 525.21 0.005647 752.93 0.010116 1348.74 Children 1 2 yrs: 0.001639 218.58 0.002738 365.03 0.003982 530.88 Children 3 5 yrs: 0.001498 199.67 0.002347 312.97 0.003831 510.81 Children 6 12 yrs: 0.001043 139.00 0.001733 231.13 0.002367 315.64 Youth 13 19 yrs: 0.000848 113.01 0.001426 190.14 0.002565 341.98 Adults 20 49 yrs: 0.000968 129.06 0.001621 216.14 0.002932 390.96 Adults 50+ yrs: 0.000874 116.55 0.001250 166.68 0.002027 270.30 Females 13 49 yrs: Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 191 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB AL GROUNDWATER ( 1994 98 data) Residue file: GW AL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 20: 06 Residue file dated: 04 26 2006/ 10: 11: 34/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001045 139.30 0.001962 261.65 0.003926 523.51 All infants: 0.003939 525.21 0.005647 752.93 0.010116 1348.74 Children 1 2 yrs: 0.001639 218.58 0.002738 365.03 0.003982 530.88 Children 3 5 yrs: 0.001498 199.67 0.002347 312.97 0.003831 510.81 Children 6 12 yrs: 0.001043 139.00 0.001733 231.13 0.002367 315.64 Youth 13 19 yrs: 0.000848 113.01 0.001426 190.14 0.002565 341.98 Adults 20 49 yrs: 0.000968 129.06 0.001621 216.14 0.002932 390.96 Adults 50+ yrs: 0.000874 116.55 0.001250 166.68 0.002027 270.30 Females 13 49 yrs: 0.000973 129.80 0.001567 208.90 0.002778 370.46 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB AL GROUNDWATER ( 1994 98 data) Residue file: GW AL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 18: 59 Residue file dated: 04 26 2006/ 10: 11: 34/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001045 160.73 0.001962 301.91 0.003926 604.05 All infants: 0.003939 606.02 0.005647 868.77 0.010116 1556.24 Children 1 2 yrs: 0.001639 252.21 0.002738 421.19 0.003982 612.56 Children 3 5 yrs: 0.001498 230.39 0.002347 361.12 0.003831 589.40 Children 6 12 yrs: 0.001043 160.39 0.001733 266.68 0.002367 364.20 Youth 13 19 yrs: 0.000848 130.40 0.001426 219.39 0.002565 394.59 Adults 20 49 yrs: 0.000968 148.92 0.001621 249.39 0.002932 451.11 Adults 50+ yrs: 0.000874 134.48 0.001250 192.32 0.002027 311.88 Females 13 49 yrs: 0.000973 149.76 0.001567 241.04 0.002778 427.45 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 192 of 203 Groundwater  CA U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB CA GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW CA. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 12: 12/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.006400 1.000 1.000 86020000 O Water, indirect, all sources 0.006400 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB CA GROUNDWATER ( 1994 98 data) Residue file: GW CA. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 24: 07 Residue file dated: 04 26 2006/ 10: 12: 12/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000334 66.87 0.000628 125.59 0.001256 251.28 All infants: 0.001261 252.10 0.001807 361.41 0.003237 647.40 Children 1 2 yrs: 0.000525 104.92 0.000876 175.21 0.001274 254.82 Children 3 5 yrs: 0.000479 95.84 0.000751 150.23 0.001226 245.19 Children 6 12 yrs: 0.000334 66.72 0.000555 110.94 0.000758 151.51 Youth 13 19 yrs: 0.000271 54.25 0.000456 91.27 0.000821 164.15 Adults 20 49 yrs: 0.000310 61.95 0.000519 103.75 0.000938 187.66 Adults 50+ yrs: 0.000280 55.94 0.000400 80.01 0.000649 129.74 Females 13 49 yrs: 0.000312 62.30 0.000501 100.27 0.000889 177.82 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 193 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB CA GROUNDWATER ( 1994 98 data) Residue file: GW CA. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 25: 52 Residue file dated: 04 26 2006/ 10: 12: 12/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000334 44.58 0.000628 83.73 0.001256 167.52 All infants: 0.001261 168.07 0.001807 240.94 0.003237 431.60 Children 1 2 yrs: 0.000525 69.95 0.000876 116.81 0.001274 169.88 Children 3 5 yrs: 0.000479 63.90 0.000751 100.15 0.001226 163.46 Children 6 12 yrs: 0.000334 44.48 0.000555 73.96 0.000758 101.01 Youth 13 19 yrs: 0.000271 36.16 0.000456 60.84 0.000821 109.43 Adults 20 49 yrs: 0.000310 41.30 0.000519 69.16 0.000938 125.11 Adults 50+ yrs: 0.000280 37.30 0.000400 53.34 0.000649 86.50 Females 13 49 yrs: 0.000312 41.53 0.000501 66.85 0.000889 118.55 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB CA GROUNDWATER ( 1994 98 data) Residue file: GW CA. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 25: 11 Residue file dated: 04 26 2006/ 10: 12: 12/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000334 51.44 0.000628 96.61 0.001256 193.30 All infants: 0.001261 193.93 0.001807 278.01 0.003237 498.00 Children 1 2 yrs: 0.000525 80.71 0.000876 134.78 0.001274 196.02 Children 3 5 yrs: 0.000479 73.73 0.000751 115.56 0.001226 188.61 Children 6 12 yrs: 0.000334 51.32 0.000555 85.34 0.000758 116.54 Youth 13 19 yrs: 0.000271 41.73 0.000456 70.21 0.000821 126.27 Adults 20 49 yrs: 0.000310 47.65 0.000519 79.80 0.000938 144.36 Adults 50+ yrs: 0.000280 43.03 0.000400 61.54 0.000649 99.80 Females 13 49 yrs: 0.000312 47.92 0.000501 77.13 0.000889 136.79 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 194 of 203 Groundwater  FL U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB FL GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW FL. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 12: 39/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.009300 1.000 1.000 86020000 O Water, indirect, all sources 0.009300 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL GROUNDWATER ( 1994 98 data) Residue file: GW FL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 27: 23 Residue file dated: 04 26 2006/ 10: 12: 39/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000486 97.16 0.000913 182.50 0.001826 365.15 All infants: 0.001832 366.34 0.002626 525.17 0.004704 940.75 Children 1 2 yrs: 0.000762 152.46 0.001273 254.61 0.001851 370.29 Children 3 5 yrs: 0.000696 139.27 0.001091 218.30 0.001781 356.29 Children 6 12 yrs: 0.000485 96.96 0.000806 161.21 0.001101 220.16 Youth 13 19 yrs: 0.000394 78.83 0.000663 132.62 0.001193 238.53 Adults 20 49 yrs: 0.000450 90.02 0.000754 150.75 0.001363 272.70 Adults 50+ yrs: 0.000406 81.29 0.000581 116.26 0.000943 188.53 Females 13 49 yrs: 0.000453 90.53 0.000729 145.71 0.001292 258.40 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 195 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL GROUNDWATER ( 1994 98 data) Residue file: GW FL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 28: 54 Residue file dated: 04 26 2006/ 10: 12: 39/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT Brain =============================================================================== Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000486 64.78 0.000913 121.67 0.001826 243.43 All infants: 0.001832 244.22 0.002626 350.11 0.004704 627.17 Children 1 2 yrs: 0.000762 101.64 0.001273 169.74 0.001851 246.86 Children 3 5 yrs: 0.000696 92.85 0.001091 145.53 0.001781 237.53 Children 6 12 yrs: 0.000485 64.64 0.000806 107.47 0.001101 146.77 Youth 13 19 yrs: 0.000394 52.55 0.000663 88.41 0.001193 159.02 Adults 20 49 yrs: 0.000450 60.01 0.000754 100.50 0.001363 181.80 Adults 50+ yrs: 0.000406 54.20 0.000581 77.51 0.000943 125.69 Females 13 49 yrs: 0.000453 60.35 0.000729 97.14 0.001292 172.26 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB FL GROUNDWATER ( 1994 98 data) Residue file: GW FL. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 28: 54 Residue file dated: 04 26 2006/ 10: 12: 39/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ============================================================================== Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000486 64.78 0.000913 121.67 0.001826 243.43 All infants: 0.001832 244.22 0.002626 350.11 0.004704 627.17 Children 1 2 yrs: 0.000762 101.64 0.001273 169.74 0.001851 246.86 Children 3 5 yrs: 0.000696 92.85 0.001091 145.53 0.001781 237.53 Children 6 12 yrs: 0.000485 64.64 0.000806 107.47 0.001101 146.77 Youth 13 19 yrs: 0.000394 52.55 0.000663 88.41 0.001193 159.02 Adults 20 49 yrs: 0.000450 60.01 0.000754 100.50 0.001363 181.80 Adults 50+ yrs: 0.000406 54.20 0.000581 77.51 0.000943 125.69 Females 13 49 yrs: 0.000453 60.35 0.000729 97.14 0.001292 172.26 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 196 of 203 Groundwater  ID U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB ID GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW ID. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 13: 13/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.002100 1.000 1.000 86020000 O Water, indirect, all sources 0.002100 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID GROUNDWATER ( 1994 98 data) Residue file: GW ID. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 30: 29 Residue file dated: 04 26 2006/ 10: 13: 13/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000110 21.94 0.000206 41.21 0.000412 82.45 All infants: 0.000414 82.72 0.000593 118.59 0.001062 212.43 Children 1 2 yrs: 0.000172 34.43 0.000287 57.49 0.000418 83.61 Children 3 5 yrs: 0.000157 31.45 0.000246 49.29 0.000402 80.45 Children 6 12 yrs: 0.000109 21.89 0.000182 36.40 0.000249 49.71 Youth 13 19 yrs: 0.000089 17.80 0.000150 29.95 0.000269 53.86 Adults 20 49 yrs: 0.000102 20.33 0.000170 34.04 0.000308 61.58 Adults 50+ yrs: 0.000092 18.36 0.000131 26.25 0.000213 42.57 Females 13 49 yrs: 0.000102 20.44 0.000165 32.90 0.000292 58.35 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 197 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID GROUNDWATER ( 1994 98 data) Residue file: GW ID. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 32: 09 Residue file dated: 04 26 2006/ 10: 13: 13/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000110 14.63 0.000206 27.47 0.000412 54.97 All infants: 0.000414 55.15 0.000593 79.06 0.001062 141.62 Children 1 2 yrs: 0.000172 22.95 0.000287 38.33 0.000418 55.74 Children 3 5 yrs: 0.000157 20.97 0.000246 32.86 0.000402 53.64 Children 6 12 yrs: 0.000109 14.60 0.000182 24.27 0.000249 33.14 Youth 13 19 yrs: 0.000089 11.87 0.000150 19.96 0.000269 35.91 Adults 20 49 yrs: 0.000102 13.55 0.000170 22.69 0.000308 41.05 Adults 50+ yrs: 0.000092 12.24 0.000131 17.50 0.000213 28.38 Females 13 49 yrs: 0.000102 13.63 0.000165 21.93 0.000292 38.90 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB ID GROUNDWATER ( 1994 98 data) Residue file: GW ID. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 31: 08 Residue file dated: 04 26 2006/ 10: 13: 13/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000110 16.88 0.000206 31.70 0.000412 63.42 All infants: 0.000414 63.63 0.000593 91.22 0.001062 163.41 Children 1 2 yrs: 0.000172 26.48 0.000287 44.22 0.000418 64.32 Children 3 5 yrs: 0.000157 24.19 0.000246 37.92 0.000402 61.89 Children 6 12 yrs: 0.000109 16.84 0.000182 28.00 0.000249 38.24 Youth 13 19 yrs: 0.000089 13.69 0.000150 23.04 0.000269 41.43 Adults 20 49 yrs: 0.000102 15.64 0.000170 26.19 0.000308 47.37 Adults 50+ yrs: 0.000092 14.12 0.000131 20.19 0.000213 32.75 Females 13 49 yrs: 0.000102 15.73 0.000165 25.31 0.000292 44.88 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 198 of 203 Groundwater  RI U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB RI GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW RI. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 09: 48: 43/ 8 Reference dose ( aRfD) = 0.0005 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.024000 1.000 1.000 86020000 O Water, indirect, all sources 0.024000 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB RI GROUNDWATER ( 1994 98 data) Residue file: GW RI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 09: 50: 26 Residue file dated: 04 26 2006/ 09: 48: 43/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001254 250.75 0.002355 470.97 0.004712 942.31 All infants: 0.004727 945.39 0.006776 1355.28 0.012139 2427.74 Children 1 2 yrs: 0.001967 393.44 0.003285 657.05 0.004778 955.59 Children 3 5 yrs: 0.001797 359.41 0.002817 563.35 0.004597 919.46 Children 6 12 yrs: 0.001251 250.21 0.002080 416.03 0.002841 568.15 Youth 13 19 yrs: 0.001017 203.42 0.001711 342.25 0.003078 615.56 Adults 20 49 yrs: 0.001162 232.31 0.001945 389.04 0.003519 703.74 Adults 50+ yrs: 0.001049 209.79 0.001500 300.02 0.002433 486.54 Females 13 49 yrs: 0.001168 233.63 0.001880 376.02 0.003334 666.83 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 199 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB RI GROUNDWATER ( 1994 98 data) Residue file: GW RI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 09: 53: 40 Residue file dated: 04 26 2006/ 09: 48: 43/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001254 166.06 0.002355 311.90 0.004712 624.05 All infants: 0.004727 626.08 0.006776 897.53 0.012139 1607.77 Children 1 2 yrs: 0.001967 260.56 0.003285 435.13 0.004778 632.84 Children 3 5 yrs: 0.001797 238.02 0.002817 373.08 0.004597 608.92 Children 6 12 yrs: 0.001251 165.70 0.002080 275.52 0.002841 376.26 Youth 13 19 yrs: 0.001017 134.72 0.001711 226.66 0.003078 407.65 Adults 20 49 yrs: 0.001162 153.85 0.001945 257.65 0.003519 466.05 Adults 50+ yrs: 0.001049 138.94 0.001500 198.69 0.002433 322.21 Females 13 49 yrs: 0.001168 154.72 0.001880 249.02 0.003334 441.61 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB RI GROUNDWATER ( 1994 98 data) Residue file: GW RI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 09: 55: 06 Residue file dated: 04 26 2006/ 09: 48: 43/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001254 191.41 0.002355 359.52 0.004712 719.32 All infants: 0.004727 721.67 0.006776 1034.56 0.012139 1853.24 Children 1 2 yrs: 0.001967 300.34 0.003285 501.57 0.004778 729.45 Children 3 5 yrs: 0.001797 274.36 0.002817 430.04 0.004597 701.88 Children 6 12 yrs: 0.001251 191.00 0.002080 317.58 0.002841 433.71 Youth 13 19 yrs: 0.001017 155.28 0.001711 261.26 0.003078 469.89 Adults 20 49 yrs: 0.001162 177.34 0.001945 296.98 0.003519 537.20 Adults 50+ yrs: 0.001049 160.15 0.001500 229.02 0.002433 371.40 Females 13 49 yrs: 0.001168 178.34 0.001880 287.04 0.003334 509.03 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 200 of 203 Groundwater  WI U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB WI GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW WI. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 13: 50/ 8 Reference dose ( aRfD) = 0.0005 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Comment Code Grp Food Name ( ppm) # 1 # 2        86010000 O Water, direct, all sources 0.023000 1.000 1.000 86020000 O Water, indirect, all sources 0.023000 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WI GROUNDWATER ( 1994 98 data) Residue file: GW WI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 34: 36 Residue file dated: 04 26 2006/ 10: 13: 50/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001201 240.30 0.002257 451.35 0.004515 903.05 All infants: 0.004530 906.00 0.006494 1298.81 0.011633 2326.58 Children 1 2 yrs: 0.001885 377.05 0.003148 629.67 0.004579 915.77 Children 3 5 yrs: 0.001722 344.44 0.002699 539.88 0.004406 881.15 Children 6 12 yrs: 0.001199 239.78 0.001993 398.69 0.002722 544.48 Youth 13 19 yrs: 0.000975 194.95 0.001640 327.99 0.002950 589.91 Adults 20 49 yrs: 0.001113 222.63 0.001864 372.83 0.003372 674.41 Adults 50+ yrs: 0.001005 201.05 0.001438 287.52 0.002331 466.27 Females 13 49 yrs: 0.001119 223.90 0.001802 360.35 0.003195 639.04 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 201 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WI GROUNDWATER ( 1994 98 data) Residue file: GW WI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 36: 08 Residue file dated: 04 26 2006/ 10: 13: 50/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001201 160.20 0.002257 300.90 0.004515 602.03 All infants: 0.004530 604.00 0.006494 865.87 0.011633 1551.05 Children 1 2 yrs: 0.001885 251.37 0.003148 419.78 0.004579 610.51 Children 3 5 yrs: 0.001722 229.62 0.002699 359.92 0.004406 587.43 Children 6 12 yrs: 0.001199 159.85 0.001993 265.80 0.002722 362.99 Youth 13 19 yrs: 0.000975 129.96 0.001640 218.66 0.002950 393.27 Adults 20 49 yrs: 0.001113 148.42 0.001864 248.56 0.003372 449.61 Adults 50+ yrs: 0.001005 134.03 0.001438 191.68 0.002331 310.85 Females 13 49 yrs: 0.001119 149.26 0.001802 240.23 0.003195 426.03 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WI GROUNDWATER ( 1994 98 data) Residue file: GW WI. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 35: 23 Residue file dated: 04 26 2006/ 10: 13: 50/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.001201 184.84 0.002257 347.19 0.004515 694.65 All infants: 0.004530 696.92 0.006494 999.08 0.011633 1789.68 Children 1 2 yrs: 0.001885 290.04 0.003148 484.36 0.004579 704.44 Children 3 5 yrs: 0.001722 264.95 0.002699 415.29 0.004406 677.81 Children 6 12 yrs: 0.001199 184.45 0.001993 306.69 0.002722 418.83 Youth 13 19 yrs: 0.000975 149.96 0.001640 252.30 0.002950 453.78 Adults 20 49 yrs: 0.001113 171.26 0.001864 286.80 0.003372 518.78 Adults 50+ yrs: 0.001005 154.66 0.001438 221.17 0.002331 358.67 Females 13 49 yrs: 0.001119 172.23 0.001802 277.19 0.003195 491.57 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 202 of 203 Groundwater  WY U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID Acute analysis for ALDICARB WY GROUNDWATER Residue file name: P:\ FFORT\$ My Files\ Aldicarb Dietary\ water April 2006\ GW WY. R98 Analysis Date 04 26 2006 Residue file dated: 04 26 2006/ 10: 14: 32/ 8 Reference dose ( aRfD) = 0.00075 mg/ kg bw/ day  EPA Crop Def Res Adj. Factors Code Grp Food Name ( ppm) # 1 # 2       86010000 O Water, direct, all sources 0.009700 1.000 1.000 86020000 O Water, indirect, all sources 0.009700 1.000 1.000 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WY GROUNDWATER ( 1994 98 data) Residue file: GW WY. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 41: 21 Residue file dated: 04 26 2006/ 10: 14: 32/ 8 Daily totals for food and foodform consumption used. Run Comment: RAT RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000507 101.34 0.000952 190.35 0.001904 380.85 All infants: 0.001910 382.09 0.002739 547.76 0.004906 981.21 Children 1 2 yrs: 0.000795 159.02 0.001328 265.56 0.001931 386.22 Children 3 5 yrs: 0.000726 145.26 0.001138 227.69 0.001858 371.62 Children 6 12 yrs: 0.000506 101.13 0.000841 168.14 0.001148 229.63 Youth 13 19 yrs: 0.000411 82.22 0.000692 138.33 0.001244 248.79 Adults 20 49 yrs: 0.000469 93.89 0.000786 157.24 0.001422 284.43 Adults 50+ yrs: 0.000424 84.79 0.000606 121.26 0.000983 196.64 Females 13 49 yrs: 0.000472 94.43 0.000760 151.97 0.001348 269.51 Attachment 16: Analysis 12  Drinking Water Assessments  Food Residues Not Included.

Page 203 of 203 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WY GROUNDWATER ( 1994 98 data) Residue file: GW WY. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 42: 42 Residue file dated: 04 26 2006/ 10: 14: 32/ 8 Daily totals for food and foodform consumption used. Run Comment: Rat Brain ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000507 67.56 0.000952 126.90 0.001904 253.90 All infants: 0.001910 254.73 0.002739 365.17 0.004906 654.14 Children 1 2 yrs: 0.000795 106.01 0.001328 177.04 0.001931 257.48 Children 3 5 yrs: 0.000726 96.84 0.001138 151.79 0.001858 247.74 Children 6 12 yrs: 0.000506 67.42 0.000841 112.10 0.001148 153.09 Youth 13 19 yrs: 0.000411 54.81 0.000692 92.22 0.001244 165.86 Adults 20 49 yrs: 0.000469 62.60 0.000786 104.83 0.001422 189.62 Adults 50+ yrs: 0.000424 56.53 0.000606 80.84 0.000983 131.10 Females 13 49 yrs: 0.000472 62.95 0.000760 101.32 0.001348 179.67 U. S. Environmental Protection Agency Ver. 2.02 DEEM FCID ACUTE Analysis for ALDICARB WY GROUNDWATER ( 1994 98 data) Residue file: GW WY. R98 Adjustment factor # 2 NOT used. Analysis Date: 04 26 2006/ 10: 42: 02 Residue file dated: 04 26 2006/ 10: 14: 32/ 8 Daily totals for food and foodform consumption used. Run Comment: Human RBC ===============================================================================

Summary calculations ( per capita):

95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD       U. S. Population: 0.000507 77.96 0.000952 146.42 0.001904 292.96 All infants: 0.001910 293.92 0.002739 421.35 0.004906 754.78 Children 1 2 yrs: 0.000795 122.32 0.001328 204.28 0.001931 297.09 Children 3 5 yrs: 0.000726 111.74 0.001138 175.14 0.001858 285.86 Children 6 12 yrs: 0.000506 77.79 0.000841 129.34 0.001148 176.64 Youth 13 19 yrs: 0.000411 63.24 0.000692 106.40 0.001244 191.38 Adults 20 49 yrs: 0.000469 72.23 0.000786 120.95 0.001422 218.79 Adults 50+ yrs: 0.000424 65.22 0.000606 93.28 0.000983 151.26 Females 13 49 yrs: 0.000472 72.64 0.000760 116.90 0.001348 207.32


P-20-0002 Sanitized Support Documents Index:
 P-20-0002 Sanitized Determination Document (linked)
 P-20-0002 Sanitized CHEM Report (attached)
 P-20-0002 Sanitized ECO Report (attached)
 P-20-0002 Sanitized ENG Report (attached)
 P-20-0002 Sanitized EXP Report (attached)
 P-20-0002 Sanitized Fate Report (attached)
 P-20-0002 Sanitized HLTH Report_POST-FOCUS FINAL (attached)


[Federal Register Volume 86, Number 68 (Monday, April 12, 2021)]
[Rules and Regulations]
[Pages 18887-18890]
[FR Doc No: 2021-07422]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

14 CFR Part 39

[Docket No. FAA-2020-0991; Project Identifier AD-2020-00478-Q;
Amendment 39-21509; AD 2021-08-15]
RIN 2120-AA64

Airworthiness Directives; Garmin International GMN-00962 GTS
Processor Units

AGENCY: Federal Aviation Administration (FAA), DOT.

ACTION: Final rule.

-----------------------------------------------------------------------

SUMMARY: The FAA is adopting a new airworthiness directive (AD) for
certain Garmin International (Garmin) GMN-00962 GTS processor units
(GTS 825, GTS 855, GTS 8000). This AD was prompted by reports of GTS
processor units issuing resolution advisories (RAs) when no risk of
collision or loss of separation exists between the airplanes involved.
This AD requires updating the software version of the affected GTS
Processor units. The FAA is issuing this AD to address the unsafe
condition on these products.

DATES: This AD is effective May 17, 2021.

ADDRESSES: For service information identified in this final rule,
contact Garmin International, Garmin Aviation Support 1200 E. 151st
Street, Olathe, KS 66062; phone:<PHONE_NUMBER>; website: https://fly.garmin.com/fly-garmin/support/. You may view this service
information at the FAA, Airworthiness Products Section, Operational
Safety Branch, 901 Locust St., Kansas City, MO 64106. For information
on the availability of this material at the FAA, call<PHONE_NUMBER>.

Examining the AD Docket

    You may examine the AD docket at https://www.regulations.gov by
searching for and locating Docket No. FAA-2020-0991; or in person at
Docket Operations between 9 a.m. and 5 p.m., Monday through Friday,
except Federal holidays. The AD docket contains this final rule, any
comments received, and other information. The address for Docket
Operations is U.S. Department of Transportation, Docket Operations, M-
30, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue
SE, Washington, DC 20590.

FOR FURTHER INFORMATION CONTACT: Paul Rau, Aviation Safety Engineer,
Wichita ACO Branch, FAA, 1801 Airport Road, Wichita, KS 67209; phone:
(316) 946-4149; fax:<PHONE_NUMBER>; email<EMAIL_ADDRESS>or
<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION:

Background

    The FAA issued a notice of proposed rulemaking (NPRM) to amend 14
CFR part 39 by adding an AD that would apply to Garmin GMN-00962 GTS
processor units (GTS 825, GTS 855, GTS 8000) with part number 011-
02571-0( ) and software version 3.13 or earlier (except version
3.12.1). The NPRM published in the Federal Register on December 14,
2020 (85 FR 80696). The NPRM was prompted by seven reports of false RAs
involving aircraft equipped with Garmin GMN-00962 GTS processor
configured for traffic collision avoidance system II (TCAS II)

(configuration marketed as GTS-8000 units). The Garmin GMN-00962 GTS
processor units are marketed by Garmin as the GTS 825, GTS 855 or GTS
8000, with the marketing name representing the traffic system
configuration.
    A false RA occurs when there is no risk of collision or loss of
separation of the airplanes. These false RAs result from the GTS
Processor software potentially calculating incorrect range rates. This
results in traffic advisories or RAs being generated when targets are
greater than 10 nautical miles (NM) away. A TCAS event involving three
or more airplanes can result in mid-air collision by increasing the
risk that the TCAS, in resolving the false RA with the initial
airplane, will create an actual loss of separation with a third
airplane. This condition, if not addressed, could result in an RA being
generated when no risk of loss of separation or risk of collision
exists between the airplanes involved, which can lead to a mid-air
collision with a third airplane.
    In the NPRM, the FAA proposed to require updating the GTS processor
unit software. The FAA is issuing this AD to address the unsafe
condition on these products.
    The affected GTS processor units were installed on the airplanes
listed below during production and via an STC; however, the affected
units may have been installed on other airplane models as a
supplemental type certificate (STC). Although the names found in
parenthesis may not be listed on the type certificate, the manufacturer
may use those names as marketing names for the airplanes.
     Textron Aviation Inc. (type certificate previously held by
Cessna Aircraft Company) Model 525 (Cessna Citation M2), Model 525B
(Cessna Citation CJ3+), Model Model 680 Sovereign, Model 680A Latitude,
and Model 700 (Cessna Citation Longitude);
     Embraer S.A. Model EMB-500 (Phenom 100) and Model EMB-505
(Phenom 300);
     Learjet Inc. Model 45 (Learjet 70) and Model 45 (Learjet
75); and
     Viking Air Limited (type certificate previously held by
Shorts Brothers PLC, Shorts Brothers Limited) Model SD3-60 SHERPA,
modified by Field Aerospace STC No. ST00865DE.

Discussion of Final Airworthiness Directive Comments

    The FAA received comments from six commenters. The commenters were
Garmin, Learjet Inc. (Learjet), Textron Aviation Inc. (Textron),
NetJets, Field Aerospace, and an individual. The following presents the
comments received on the NPRM and the FAA's response to each comment.

Supportive

    An individual commenter supported the NPRM without change.

Request Regarding Applicability

    Garmin requested the FAA clarify the AD applicability, as the
proposed AD applies to GTS 825 and GTS 855, which are not affected by
the false RA issue. Garmin suggested that the FAA add a clarifying
statement to the background section, and revise the applicability
paragraph to remove references to the GTS 825 and GTS 855.
    The FAA disagrees. This AD applies to the GTS Processor part number
011-02571-0( ) units with software version 3.13 or earlier, except
software version 3.12.1. The GTS 825, GTS 855, and GTS 8000 marketing
labels describe different installation configurations rather than
different appliances. While the GTS Processor will not generate false
RAs when configured as TAS (GTS 825) or TCAS I (GTS 855), the appliance
itself is still susceptible to the issue, and the unsafe condition
would occur if an operator enables the TCAS II option without also
updating the software.
    The FAA did not change this AD based on this comment.

Request Regarding Affected Aircraft

    Field Aerospace stated that the proposed AD would affect Shorts
Sherpa Model SD3-60 airplanes that have been modified under Field
Aerospace STC No. ST00865DE.
    The FAA agrees with this comment. The FAA issued this AD against
the Garmin appliance because the unsafe condition exists in the
appliance. The FAA has added Model SD3-60 SHERPA airplanes modified by
Field Aerospace STC No. ST00865DE to the list of known affected
aircraft in the background section. This is not an all-inclusive list;
all operators must check their airplanes for the affected appliance,
regardless of whether the model of their airplane is listed.

Request Regarding Unsafe Condition

    Garmin requested the FAA add information relevant to the actual
risk in the discussion of the unsafe condition in the background
section. Specifically, Garmin stated that loss of separation with a
third airplane is not inevitable when a false RA occurs. Garmin further
stated that the TCAS II implemented by the GTS 8000 is capable of
negotiating threats with more than one airplane and will adjust the RA
in a situation should loss of separation to a third airplane result in
a collision threat.
    The FAA disagrees. The unsafe condition statement describes the
condition the FAA is trying to prevent; as such, it does not describe
all possible outcomes. The FAA assessed the likelihood of the unsafe
condition in determining whether an AD or other action was warranted.
While the FAA acknowledges that no loss of separation event has been
associated with this issue on Garmin equipment, a similar issue with
other TCAS II equipment has resulted in loss of separation events.
Additionally, the rate of false RAs observed with GTS Processor-
equipped aircraft far exceeds the acceptable probability of a false RA
due to a failure of the system specified in Advisory Circular No. 20-
151C, Airworthiness Approval of Traffic Alert and Collision Avoidance
Systems (TCAS II), Versions 7.0 & 7.1 and Associated Mode S
Transponders, dated July 21, 2017. Further, the potential for a loss of
separation is not limited to the GTS Processor-equipped aircraft, as
the second aircraft may also contain equipment that attempts to resolve
the multi-threat encounter. Although the TCAS II is capable of
resolving conflicts with more than one aircraft, since the current
design of TCAS RAs is limited to vertical maneuvers, it is not able to
provide conflict resolution for all encounters involving multiple
aircraft.
    The FAA did not change this AD based on this comment.

Request Regarding Required Actions and Compliance

    Garmin requested the FAA revise the AD to require updating the
affected software to version 3.12.1, or to version 3.14 or later.
Garmin stated that, as proposed, the AD would not allow update of
software to version 3.12.1, which is not affected by the issue.
    The FAA agrees with this comment. The unsafe condition is also
resolved in version 3.12.1. The FAA has changed the Required Actions
and Compliance paragraph to also allow updating the GTS processor
software to version 3.12.1.
    Learjet, Textron, and NetJets requested the FAA extend the
compliance time to allow adequate time for the certification and
deployment of the required changes to all affected products. Learjet
requested a compliance time of 18 months, while Textron requested a
compliance time of 24 months.
    The FAA agrees. In addition to the reasons provided by the
commenters, the FAA's risk assessment, in consideration of the ongoing
pandemic and resulting reduction in air traffic,

supports extending the compliance time from 12 to 24 months.

Request Regarding Costs

    Textron requested the FAA update the estimated cost information to
include additional work for Textron aircraft. Textron stated it has
prior agreements with Garmin to accomplish this software change as part
of a package of other product improvements, for a per-aircraft cost of
approximately $3,000.
    The FAA disagrees with this comment. The cost analysis in AD
rulemaking actions typically includes only the costs associated with
complying with the AD. This AD does not mandate the entire package of
changes for Textron aircraft.
    The FAA has not made changes to this AD based on this comment.

Request Regarding Certificate of Airworthiness

    Learjet requested the FAA revise the AD to allow initial
Certificates of Airworthiness to be issued to newly-manufactured
aircraft prior to complying with the AD. Learjet stated that
certification of new software to comply with the AD (software later
than version 3.13) will take a minimum of 9 months.
    The FAA disagrees with this comment. The AD does not prohibit the
issuance of a Certificate of Airworthiness to eligible aircraft. Newly-
manufactured aircraft need to comply with the AD actions within the
same timeframe as aircraft in the current U.S. fleet.
    The FAA has not made changes to this AD based on this comment.

Conclusion

    The FAA reviewed the relevant data, considered any comments
received, and determined that air safety requires adopting this AD as
proposed. Accordingly, the FAA is issuing this AD to address the unsafe
condition on these products. Except for minor editorial changes and any
other changes described previously, this AD is adopted as proposed in
the NPRM. None of the changes will increase the economic burden on any
operator.

Related Service Information

    The FAA reviewed Garmin Service Bulletin No. 2065, Revision A,
dated May 7, 2020; and Garmin Service Bulletin No. 1948, Revision B,
dated March 26, 2020. These service bulletins contain procedures for
uploading the software update to the GMN-00962 GTS Processor units (GTS
825, GTS 855, GTS 8000).

Costs of Compliance

    The FAA estimates that this AD affects 700 appliances installed on
airplanes of U.S. registry.
    The FAA estimates the following costs to comply with this AD:

                                                 Estimated Costs
----------------------------------------------------------------------------------------------------------------
                                                                                Cost per      Cost on U.S.
                Action                         Labor cost           Parts cost        product        operators
----------------------------------------------------------------------------------------------------------------
Update GTS Processor software.........  4.00 work-hours x $85                 $0            $340        $238,000
                                         per hour = $340.
----------------------------------------------------------------------------------------------------------------

Authority for This Rulemaking

    Title 49 of the United States Code specifies the FAA's authority to
issue rules on aviation safety. Subtitle I, section 106, describes the
authority of the FAA Administrator. Subtitle VII: Aviation Programs,
describes in more detail the scope of the Agency's authority.
    The FAA is issuing this rulemaking under the authority described in
Subtitle VII, Part A, Subpart III, Section 44701: General requirements.
Under that section, Congress charges the FAA with promoting safe flight
of civil aircraft in air commerce by prescribing regulations for
practices, methods, and procedures the Administrator finds necessary
for safety in air commerce. This regulation is within the scope of that
authority because it addresses an unsafe condition that is likely to
exist or develop on products identified in this rulemaking action.

Regulatory Findings

    This AD will not have federalism implications under Executive Order
13132. This AD will not have a substantial direct effect on the States,
on the relationship between the national government and the States, or
on the distribution of power and responsibilities among the various
levels of government.
    For the reasons discussed above, I certify that this AD:
    (1) Is not a ``significant regulatory action'' under Executive
Order 12866,
    (2) Will not affect intrastate aviation in Alaska, and
    (3) Will not have a significant economic impact, positive or
negative, on a substantial number of small entities under the criteria
of the Regulatory Flexibility Act.

List of Subjects in 14 CFR Part 39

    Air transportation, Aircraft, Aviation safety, Incorporation by
reference, Safety.

The Amendment

    Accordingly, under the authority delegated to me by the
Administrator, the FAA amends 14 CFR part 39 as follows:

PART 39--AIRWORTHINESS DIRECTIVES

0
1. The authority citation for part 39 continues to read as follows:

    Authority:  49 U.S.C. 106(g), 40113, 44701.

Sec.  39.13  [Amended]

0
2. The FAA amends Sec.  39.13 by adding the following new airworthiness
directive:

2021-08-15 Garmin International: Amendment 39-21509; Docket No. FAA-
2020-0991; Project Identifier AD-2020-00478-Q.

(a) Effective Date

    This airworthiness directive (AD) is effective May 17, 2021.

(b) Affected ADs

    None.

(c) Applicability

    This AD applies to Garmin International GMN-00962 GTS processor
units, part number 011-02571-0( ), with software version 3.13 or
earlier, except software version 3.12.1, installed on airplanes
certificated in any category. These units are marketed as the GTS
825, GTS 855, or GTS 8000.

(d) Subject

    Joint Aircraft System Component (JASC) Code 3445, AIR COLLISION
AVOIDANCE SYSTEM (TCAS).

(e) Unsafe Condition

    This AD was prompted by the GTS processor unit issuing false
resolution advisories (RAs) when no risk of collision or loss of
separation exists between the airplanes involved. A traffic
collision avoidance system (TCAS) event involving

three or more airplanes can result in mid-air collision by
increasing the risk that the TCAS, in resolving the false RA between
the initial airplane, will create an actual loss of separation with
a third airplane. The FAA is issuing this AD to prevent these false
RAs, which can lead to a mid-air collision with a third airplane.

(f) Required Action and Compliance

    Within 24 months after the effective date of this AD, update the
GTS processor software to a version that is not 3.13 or earlier,
except 3.12.1. Software version 3.12.1 does not contain the unsafe
condition.

(g) Alternative Methods of Compliance (AMOCs)

    (1) The Manager, Wichita ACO Branch, FAA, has the authority to
approve AMOCs for this AD, if requested using the procedures found
in 14 CFR 39.19. In accordance with 14 CFR 39.19, send your request
to your principal inspector or local Flight Standards District
Office, as appropriate. If sending information directly to the
manager of the certification office, send it to the attention of the
person identified in Related Information.
    (2) Before using any approved AMOC, notify your appropriate
principal inspector, or lacking a principal inspector, the manager
of the local flight standards district office/certificate holding
district office.

(h) Related Information

    (1) For more information about this AD, contact Paul Rau,
Aviation Safety Engineer, Wichita ACO Branch, FAA, 1801 Airport
Road, Wichita, KS 67209; phone:<PHONE_NUMBER>; fax:<PHONE_NUMBER>;
email<EMAIL_ADDRESS>or<PHONE_NUMBER>3924317d131f03103631317e373f26.
    (2) For service information identified in this AD contact Garmin
International, Garmin Aviation Support 1200 E. 151st Street, Olathe,
KS 66062; phone:<PHONE_NUMBER>; website: https://fly.garmin.com/fly-garmin/support/. You may also view this service information at
FAA, Airworthiness Products Section, Operational Safety Branch, 901
Locust St., Kansas City, MO 64106. For information on the
availability of this material at the FAA, call<PHONE_NUMBER>.

    Issued on April 7, 2021.
Lance T. Gant,
Director, Compliance & Airworthiness Division, Aircraft Certification
Service.
[FR Doc. 2021-07422 Filed 4-9-21; 8:45 am]
BILLING CODE 4910-13-P


EPA REGISTRATION DIVISION COMPANY NOTICE OF FILING FOR PESTICIDE
PETITIONS PUBLISHED IN THE FEDERAL REGISTER

EPA Registration Division contact:

Jim Tompkins,<PHONE_NUMBER> and Beth Benbow,<PHONE_NUMBER>

Bayer CropScience LP

PP#: 9F7589

	EPA has received a pesticide petition (9F7589) from Bayer CropScience
LP, [2 T. W. Alexander Drive, Research Triangle Park, NC 27709]
proposing, pursuant to section 408(d) of the Federal Food, Drug, and
Cosmetic Act (FFDCA), 21 U.S.C. 346a(d), to amend 40 CFR part 180. by
establishing a tolerance for residues of indaziflam N-[(1R,
2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1-yl-1,3,5-triazine-2,4-diamine]-6
-(1-fluoroethyl)] and its fluoroethyl-indaziflam metabolite in or on raw
agricultural commodities fruit, pome, group, fruit, citrus, group,
fruit, stone, group, nut, tree, group, pistachios, grapes, olives all at
[0.01] parts per million (ppm), and almond, hulls at [0.2] ppm, and the
import tolerance for refined sugar at [0.01] ppm.  EPA has determined
that the petition contains data or information regarding the elements
set forth in section 408 (d)(2) of  FDDCA; however, EPA has not fully
evaluated the sufficiency of the submitted data at this time or whether
the data supports granting of the petition. Additional data may be
needed before EPA rules on the petition.

A. Residue Chemistry

1. Plant metabolism. The nature of the indaziflam residues in plants and
livestock is adequately understood. The plant residues of concern for
tolerance enforcement are the combined residues of indaziflam (N-[(1R,
2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1-yl-1,3,5-triazine-2,4-diamine]-6
-(1-fluoroethyl)-] and its fluoroethyl-indaziflam metabolite
[1,3,5-triazine-2,4-diamine]-6-(1-fluoroethyl)-].

	2. Analytical method. Indaziflam residues are quantified in raw
agricultural commodities by high pressure liquid chromatography/triple
stage quadrupole mass spectrometry (LC/MS/MS) using the stable
isotopically labeled analytes as internal standards. The limit of
quantification (LOQ) for each analyte was 0.005 ppm for all commodities.

	3. Magnitude of residues. Residue trials were conducted to support the
tolerances requested above including the following:

Citrus: A total of 23 field trials were conducted evaluating residues at
target harvest intervals of 14, 45 and 240 days after application.

Pome Fruit: A total of 18 field trials were conducted evaluating
residues at target harvest intervals of 14, 45 and 210 target days after
application.

Stone Fruit: A total of 21 field trials were conducted evaluating
residues at target harvest intervals of 14, 45 and 150/210 days after
application.

Tree Nuts: A total of 10 field trials were conducted evaluating residues
at target harvest intervals of 14 days after application.

Grapes: A total of 12 field trials were conducted evaluating residues at
target harvest intervals of 14, 45 and 140-240 days after application.

Olives: A total of 6 field trials were conducted evaluating residues at
target harvest intervals of 14, 45 and 300 days after application.

Sugarcane: A sugarcane processing trial was conducted to measure the
magnitude of total indaziflam residues in sugarcane and sugarcane
processed commodities following an exaggerated rate application to
ratooned sugarcane.

B. Toxicological Profile

1. Acute toxicity.  Indaziflam has a low acute oral (LD50 > 2,000 mg/kg
bw; Category III), dermal (LD50: > 2,000 mg/kg bw; Category III) and
inhalative toxicity (LC50: > 2.30 mg/L air; Category IV) in male and
female rats.  It is not an eye or skin irritant (both Category IV) nor
is it a skin sensitizer.

	2. Genotoxicty. Indaziflam was negative for mutagenicity and
clastogenicity in all the standard in vivo and in vitro assays.

	3. Reproductive and developmental toxicity. The reproductive and
developmental studies conducted with indaziflam showed that the test
substance was not a reproductive toxicant.  Parental and offspring body
weight and/or body weight change were decreased at high concentrations,
however there was no effect on reproductive ability of adults.  The
findings observed in rat fetuses (decreased body weights) were minor and
were secondary to maternal toxicity.  There was no indication of a
teratogenic effect of indaziflam in either the rat or the rabbit.

4. Neurotoxicity. Acute, subchronic and developmental neurotoxicity of
indaziflam was assessed in the rat.  Compound-related effects following
a single oral dose of the test substance were limited to 500 mg/kg and
2000 mg/kg in males and 100 mg/kg and up in females.    SEQ CHAPTER \h
\r 1 Effects in males and/or females consisted of decreased motor and
locomotor activity on the day of treatment (with recovery by the next
test occasion), urine, oral and perianal stains (generally resolved one
to five days after treatment), tremors, increased reactivity and
decreased activity (generally resolved the following day after
treatment), salivation, cool to touch, clonic convulsions, ventrum
wet/staining and death in three females (2000 mg/kg only).   Lastly,
compound-related microscopic lesions in high-dose males described as
focal to multi-focal individual nerve fiber degeneration observed in the
gasserian ganglion and peripheral nerves (sciatic and tibial) were
evident.   Slight decreases in measures of motor and locomotor activity
were evident in females treated at 100 mg/kg, with no effect at the next
lower dose of 50 mg/kg.  Based on these results, doses of 100 and 50 mg
BCS-AA10717/kg body weight are the overall NOAELs for males and females,
respectively. In the subchronic study, there were no mortalities.
However, similar effects in motor and locomotor activity, as well as
clinical signs of neurotoxicity were only noted at the top dose, 10000
ppm (580.9 and 585.7 mg/kg/day for males and females, respectively).
These results establish a NOAEL for neurotoxicity endpoints of 8000 ppm
(243.6 mg/kg/day in males and 306.9 mg/kg/day in females).  In the
developmental neurotoxicity study, the dam and offspring NOAEL was 1000
ppm (83.8 mg/kg bw/day), based on clinical signs of toxicity in dams
(tremor, dilated pupils, nasal stains, and repetitive chewing
movements), marked decrease in body weight and body weight gain, and
decreased food consumption in dams and offspring. There were no effects
on neuropathology in this study.

	5. Subchronic toxicity. Short and Intermediate-term exposures to
indaziflam were assessed in the mouse, rat and dog.  The only treatment
related effect noted in the mouse, following a 90-day exposure, was
reduced body weights at the highest dose tested. The common target
organs in rats and dogs were the liver, thyroid, and nervous system.
Liver findings seen in rats and dogs were restricted to increased liver
weight, hepatocellular hypertrophy, and increased cholesterol.  Kidneys
were enlarged in the rat, but without corresponding weight change or
pathology.  Neurobehavioral and neuropathological changes were noted in
both rats and dogs following acute, short-term and chronic exposure to
indaziflam.  Effects noted included tremors, salivation and decreased
motor activity in rats, and uncoordinated gait and convulsions in dogs.
Neuropathological lesions included axonal swelling and degeneration, as
well as individual nerve fiber degeneration.  These findings were found
in the brain, spinal cord and peripheral (sciatic and tibial) nerve
tracts.  Indaziflam is not toxic by the dermal route, as there was no
toxicity noted at the highest dose tested (1000 mg/kg/day) in a 28-day
dermal toxicity study in rats.  The dog was the most sensitive species
overall after sub-acute to sub-chronic administration of indaziflam with
the lowest NOAEL at 7.5 mg/kg bw/day in males and females in the 90-day
oral gavage study.

	6. Chronic toxicity. Chronic toxicity of indaziflam was evaluated in
the rat, mouse and dog.  Target organs were liver, kidney, thyroid and
nervous system.  In the chronic rat, top dose females (10000 ppm)
demonstrated similar signs as that seen in the acute and subchronic
neurotoxicity studies (e.g. dilated pupil, reduced motor activity,
limited use of limbs, uncoordinated movements, tremors, hindlimbs
splayed, low alertness). The incidence of treatment-related clinical
signs in females decreased significantly after the change of dose level
from 10000 to 6000 ppm.  Clinical signs were not evident in the chronic
dog at any dose level.  Organ effects noted in these studies included
increased liver, kidney and thyroid weights, with centrilobular
hepatocellular hypertrophy in the liver, tubular hyperplasia (male mouse
only) and brown pigment in the kidney, and follicular cell hypertrophy
in the thyroid (male rat only), histopathological changes to the central
and peripheral nerve tracts were noted only in the dog. The dog was the
most sensitive species overall after chronic administration of
indaziflam with the lowest NOAEL at 2.0 mg/kg bw/day in males and
females in the 1-year oral feeding study.  There were no
treatment-related neoplasms in the rat or mouse.  Therefore, following
chronic exposure, there is no indication of oncogenic potential relevant
for the human health risk assessment of indaziflam.

	7. Animal metabolism. A metabolism study for indaziflam, in which male
rats were given single oral doses of [indane-3-14C] AE 1170437 or
[triazine-2,4-14C] AE 1170437, showed that the uptake and excretion of
AE 1170437 was rapid.  Following oral administration, greater than 87%
of the administered dose was excreted within 24 hours.  In general, the
majority of the radioactivity was excreted in the feces with fecal:
renal excretion ratios ranging from approximately 1:1 for the low dose
experiments to approximately 10:1 for the high dose experiments.  No
volatile residues were detected, and no mineralization was observed.
Residue levels in tissues were highest in GIT and liver.  Higher residue
levels were found in the residual carcass of animals in the bile
cannulation experiments.

Both uptake and clearance of indaziflam from the blood was rapid.
Females appeared to absorb slightly more material compared to for males.
 Blood residues smoothly fell off in all dose groups indicating an
absence of reuptake.

Once absorbed, the metabolism of AE 1170437 was rapid, occurring mainly
through oxidative pathways.  That portion of the administered dose
recovered as unmetabolized parent in the feces, particularly in the high
dose experiments, was likely not absorbed.

	8. Metabolite toxicology. The two major metabolites of indaziflam are
AE 2158969 (BCS-AA10717-carboxylic acid) and BCS-AA10365
(BCS-AA10717-fluoroethyldiaminotriazine, FDAT).  As both major
metabolites are common in the rat, as well as the environment, toxicity
studies conducted with the TGAS are adequate to assess any potential
toxicity from these metabolites.  Primary mutagenicity screening tests
which were conducted on the metabolites of indaziflam showed them not to
be genotoxic.

	9. Endocrine disruption. The toxicology database for Indaziflam
(BCS-AA10717) is current and complete.  Studies in this database include
evaluation of the potential effects on reproduction and development and
an evaluation of the pathology of the endocrine organs following short-
or long-term exposure.

Bayer CropScience will conduct additional testing if and when required
under the Agency’s Endocrine Disruptor Screening Program (EDSP).

C. Aggregate Exposure

Aggregate risk assessments were conducted for indaziflam including an
acute aggregate for food and drinking water exposure, a chronic
aggregate for food and drinking water exposure and a short term
aggregate assessment which includes food, drinking water and residential
exposure.  The assessments were conducted using the CARES® Version 3.0
software. Results of the short term aggregate assessment gave an MOE of
8700 for Children 1-2, the most sensitive subpopulation. The Level of
Concern for aggregate assessment of indaziflam is 100.

Dietary exposure.

	i. Food and Water.

Assessments were conducted to evaluate potential risks due to acute and
chronic dietary exposure of the U.S. population and selected population
subgroups to residues of indaziflam.  The dietary (food only) assessment
includes all proposed crops: Crop Group 10 Citrus Fruit; Crop Group 11
Pome Fruit; Crop Group 12 Stone Fruit; Crop Subgroup 13-07-F Small Fruit
Vine Climbing (except Kiwi); Crop Group 14 Tree Nuts; and olives.  The
drinking water assessment is based on conservative modeled acute and
chronic estimated drinking water concentrations for the US.  Exposure
from food and water together based on all the proposed uses of
indaziflam consumed only 1.9% of the acute RfD/PAD and 2.4% of the
chronic RfD/PAD for the most sensitive subpopulation of infants.

	2. Non-dietary exposure.

The short term residential assessment includes application exposure by
homeowners applying indaziflam on lawns or ornamental plants, as well as
post-application exposure estimates for adults and children playing on
lawns and golf courses. Residential post-application exposure from
contact with indaziflam treated turf or ornamentals on the day of
application resulted in MOEs in excess of 600 for toddlers, and in
excess of 1,000 for adults, well above the Level of Concern of 100 for
indaziflam.

D. Cumulative Effects

	The toxicological properties of indaziflam indicate that it does not
have a common mechanism of toxicity with any other compounds. Although
it contains a triazine ring it does not exhibit the toxicological
properties of the chlorotriazine common mechanism group. Therefore it is
not necessary to cumulate its exposure with any other compounds.

E. Safety Determination

	1. U.S. population Using the conservative exposure assumptions
described above and based on the completeness of the toxicity data, it
can be concluded that aggregate exposure to residues of indaziflam
present a reasonable certainty of no harm.  Exposure from residues in
crops and drinking water utilizes 1.9% of the aPAD and 2.4% of the cPAD
for the most sensitive population of infants.  EPA generally has no
concerns for exposures below 100% of the Population Adjusted Doses.
Therefore, the aggregate assessment for all proposed uses for indaziflam
demonstrates that there is a reasonable certainty that no harm will
result to the US Population and subpoppulations from the use of
indaziflam noted here.

	2. Infants and children. The developmental and reproductive toxicity of
indaziflam were evaluated in developmental toxicity studies in the rat
and rabbit, a 2-generation reproduction study in the rat and a
developmental neurotoxicity study in the rat. These studies are
discussed under Section B (Toxicology Profile) above.  The developmental
toxicity data demonstrated no increased sensitivity of rats or rabbits
to in utero exposure to indaziflam. In addition, the multi-generation
reproductive toxicity study did not identify any increased sensitivity
of rats to in utero or post-natal exposure. The developmental toxicity
studies are designed to evaluate adverse effects on the developing
organism resulting from maternal pesticide exposure during gestation.
Reproduction studies provide information relating to effects from
exposure to the pesticide on the reproductive capability of mating
animals and data on systemic toxicity.

FFDCA section 408 provides that EPA shall apply an additional tenfold
margin of safety for infants and children in the case of threshold
effects to account for pre-and post-natal toxicity and the completeness
of the data base unless EPA determines that a different margin of safety
will be safe for infants and children. The indaziflam database is
complete for FQPA purposes and there are no residual uncertainties for
pre-/post-natal toxicity for indaziflam.  Therefore, the Special FQPA
Safety Factor can be reduced to 1x.

Based on the exposure assessments described above and on the
completeness and reliability of the toxicity data, it can be concluded
that the dietary exposure from all proposed uses of indaziflam consumes
1.9% of the aRfD/aPAD at the 99.9th percentile and 2.4% of the cRfD/cPAD
for the most sensitive population subgroup of infants.  Short term
aggregate risk assessment of indaziflam which includes food, drinking
water and residential pathways gives an MOE of 8,700 for Children 1-2,
the most sensitive subpopulation for this scenario.  This is well above
the Level of Concern of 100 for indaziflam.  Thus, it can be concluded
that there is a reasonable certainty that no harm will result from
aggregate exposure to indaziflam residues.

F. International Tolerances

There currently are no international (CODEX) tolerances/MRLs for
indaziflam.

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