Triadimenol, a metabolite of triadimefon, is also a registered fungicide. Triadimenol was first registered after 1984 and is not subject to reregistration under the 1988 amendments to FIFRA.  Triadimenol is, however, subject to tolerance reassessment under the FFDCA, as amended by FQPA.  Based on its evaluation of combined exposures from the uses of triadimefon, triadimenol, and their metabolites, the Agency has determined that the tolerances for triadimefon and triadimenol are considered to be reassessed under FFDCA.

	B.	Public Comments and Responses

  SEQ CHAPTER \h \r 1 Through the Agency’s public participation process, EPA worked extensively with stakeholders and the public to reach the regulatory decisions for triadimefon.  EPA released its preliminary risk assessments for triadimefon and triadimenol for public comment on February 16, 2006, for a 60-day public comment period (Phase 3 of the public participation process).  During the public comment period on the risk assessments, which closed on April 17, 2006, the Agency received comments from a public citizen, nursery and forestry cooperatives, the U.S. Triazole Task Force, and the technical registrant Bayer CropScience.  These comments in their entirety, responses to the comments, as well as the preliminary and revised risk assessments, are available in the public docket for triadimefon (EPA-HQ-OPP-2005-0258) and for triadimenol (EPA-HQ-OPP-2006-0038) in the EPA’s electronic docket at   HYPERLINK "http://www.regulations.gov"  http://www.regulations.gov .

	C.	Regulatory Position under the FFDCA

		1.	Food Quality Protection Act Findings

“Risk Cup” Determination

As part of the FQPA tolerance reassessment process, EPA assessed the risks associated with this pesticide.  The Agency has determined that, if the mitigation described in this document is adopted and labels are amended, human health risks as a result of exposures to triadimefon and triadimenol are within acceptable levels.  In other words, EPA has concluded that the tolerances for triadimefon and triadimenol will meet FQPA safety standards.  In reaching this determination, EPA has considered the available information on the special sensitivity of infants and children, as well as exposures to triadimefon and triadimenol from all possible sources.  Furthermore, if the registrant does not cancel the uses agreed to or make the mitigation changes necessary to meet the safety determination, the Agency will take the appropriate regulatory action.

  SEQ CHAPTER \h \r 1

			b.	Determination of Safety to U.S. Population

The Agency has determined that the established tolerances for triadimefon and triadimenol, with amendments and changes as specified in this document, will meet the safety standards under the FQPA amendments to section 408(b)(2)(D) of the FFDCA, and that there is a reasonable certainty no harm will result to the general population or any subgroup from the use of triadimefon and triadimenol.  In reaching this conclusion, the Agency has considered all available information on the toxicity, use practices and exposure scenarios, and the environmental behavior of triadimefon and triadimenol and their free triazole degradates.

	As discussed in Section III, the aggregate risks from triadimefon and triadimenol from food, drinking water, and residential exposure are not of concern, provided the mitigation measures described in this document are implemented through amendments to existing registrations.  Furthermore, aggregate risks from the free triazoles (1,2,4-triazole, triazole acetic acid, and triazole alanine) are not of concern.  The aggregate risk assessment for the free triazoles considers all currently registered uses of all triazole fungicides.

			c.	Determination of Safety to Infants and Children

EPA has determined that the established tolerances for triadimefon and triadimenol, with amendments and changes as specified in this document, will meet the safety standards under the FQPA amendments to section 408(b)(2)(C) of the FFDCA, that there is a reasonable certainty of no harm for infants and children.  The safety determination for infants and children considers factors on the toxicity, use practices and environmental behavior noted above for the general population, but also takes into account the possibility of increased dietary exposure due to the specific consumption patterns of infants and children, as well as the possibility of increased susceptibility to the toxic effects of triadimefon and triadimenol residues in this population subgroup.

			d.	Endocrine Disruptor Effects

  SEQ CHAPTER \h \r 1 EPA is required under the FFDCA, as amended by FQPA, to develop a screening program to determine whether certain substances (including all pesticide active and other ingredients) “may have an effect in humans that is similar to an effect produced by a naturally occurring estrogen, or other endocrine effects as the Administrator may designate.”  Following recommendations of its Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC), EPA determined that there was a scientific basis for including, as part of the program, the androgen and thyroid hormone systems, in addition to the estrogen hormone system.  EPA also adopted EDSTAC’s recommendation to include evaluations of potential effects in wildlife.  For pesticides, EPA will use FIFRA and, to the extent that effects in wildlife may help determine whether a substance may have an effect in humans, FFDCA authority to require the wildlife evaluations.  As the science develops and resources allow, screening of additional hormone systems may be added to the Endocrine Disruptor Screening Program (EDSP).

e.	Cumulative Risks

Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider “available information” concerning the cumulative effects of a particular pesticide’s residues and “other substances that have a common mechanism of toxicity.”  Other substances are considered to account for the possibility that low-level exposures to multiple chemical substances that cause a common effect by a common mechanism could lead to the same adverse health effect as would a higher level of exposure to each individual substance.  For the purposes of this regulatory decision, EPA has concluded that triadimefon and triadimenol do not share a common mechanism of toxicity with other substances.  The Agency reached this conclusion after a thorough internal review and external review of the data supporting a common mechanism of toxicity for a number of chemical classes.  For information regarding EPA’s efforts to determine which chemicals have a common mechanism of toxicity and to evaluate the cumulative effects of such chemicals, see the policy statements released by EPA’s Office of Pesticide Programs concerning common mechanism determinations and procedures for cumulating effects from substances found to have a common mechanism on EPA’s website   HYPERLINK "http://www.epa.gov/pesicides/cumulative/"  http://www.epa.gov/pesicides/cumulative/ .

2.	Tolerance Summary for Triadimefon

  SEQ CHAPTER \h \r 1 Tolerances of triadimefon in/on plant and livestock commodities (40 CFR § 180.410) are presently expressed in terms of residues of triadimefon and its metabolites containing chlorophenoxy and triazole moieties (expressed as the parent compound).

			  SEQ CHAPTER \h \r 1 a.	Tolerances Currently Listed Under 40 CFR §180.410

  SEQ CHAPTER \h \r 1   	Tolerances are established for residues of triadimefon [1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone] and its metabolites containing chlorophenoxy and triazole moieties (expressed as the parent compound) in/on various plant and animal commodities [40 CFR §180.410].  The established tolerances for residues in plant and animal commodities [40 CFR §180.410(a)] range from 0.04 ppm (milk, hog, and poultry commodities) to 145 ppm (grass seed cleanings).  A tolerance with regional registration is established for triadimefon and its metabolites in/on raspberries at 2.0 ppm [40 CFR §180.410(c)].  However, all triadimefon tolerances (except pineapple) will be proposed for revocation.

	Residues of triadimenol (and its butanediol metabolite KWG 1342), from use of triadimenol per se, are regulated separately under 40 CFR §180.450.  In addition, 40 CFR §180.3(d)(13) specifies that where tolerances are established for residues of both 1-(4- chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazole-1-yl)-2-butanone (triadimefon) and β-(4-chlorophenoxy)-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol (triadimenol) including its butanediol metabolite, 1-(4-chlorophenoxy)-3,3-dimethyl-3-hydroxymethyl-1-(1H-1,2,4-triazol-1-y l)-2-butanol (KWG1342), in or on the same raw agricultural commodity and its products thereof, the total amount of such residues shall not yield more residue than that permitted by the higher of the two tolerances.  Currently, triadimefon and triadimenol do not share any uses, so 40 CFR §180.3(d)(13) should be deleted.  A tolerance summary for triadimefon is presented in Table 32.

Table 32.  Tolerance Summary for Triadimefon

Commodity	Current Tolerance (ppm)	Reassessed Tolerance (ppm)	Comments

  SEQ CHAPTER \h \r 1 Tolerances Established Under 40 CFR §180.410(a)

  SEQ CHAPTER \h \r 1 Apple	1	Revoke	  SEQ CHAPTER \h \r 1 Bayer is voluntarily deleting this use.

  SEQ CHAPTER \h \r 1 Apple, wet pomace and

Apple, dry pomace	4	Revoke	Bayer is voluntarily deleting this use.  SEQ CHAPTER \h \r 1

  SEQ CHAPTER \h \r 1 Barley, milled fractions (except flour)	4	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on barley.

  SEQ CHAPTER \h \r 1 Beet, sugar	0.5	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on sugar beets.

  SEQ CHAPTER \h \r 1 Beet, sugar, tops	3

  SEQ CHAPTER \h \r 1 Cattle, fat	1	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any cattle feed items.

  SEQ CHAPTER \h \r 1 40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

  SEQ CHAPTER \h \r 1 Cattle, meat	1	Revoke

	Cattle, meat byproducts	1	Revoke

	Chickpea, seed	0.1	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on chickpea plants.

  SEQ CHAPTER \h \r 1 Cucurbits	0.3	Revoke	Currently, Bayer does not have any registered uses of triadimefon on chickpea plants.

  SEQ CHAPTER \h \r 1 Eggs	0.04	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any poultry feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

  SEQ CHAPTER \h \r 1 Goat, fat	1	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any goat feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

  SEQ CHAPTER \h \r 1 Goat, meat	1	Revoke

	  SEQ CHAPTER \h \r 1 Goat, meat byproducts	1	Revoke

	  SEQ CHAPTER \h \r 1 Grape	1	Revoke	Bayer is voluntarily deleting this use.

  SEQ CHAPTER \h \r 1 Grape, wet pomace and Grape, dry pomace	3

Revoke	  SEQ CHAPTER \h \r 1 No longer considered significant livestock feed items.

  SEQ CHAPTER \h \r 1 Grape, raisin, waste	7

  SEQ CHAPTER \h \r 1 Grass, forage	0.2

Revoke

	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on pasture or rangeland.

  SEQ CHAPTER \h \r 1 Grass, seed screenings	145

  SEQ CHAPTER \h \r 1 Grass, straw, grown for seed	105

  SEQ CHAPTER \h \r 1 Hog, fat	0.04	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any hog feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

  SEQ CHAPTER \h \r 1 Hog, meat	0.04

Hog, meat byproducts	0.04

Horse, fat	1

Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any horse feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

Horse, meat	1

Horse, meat byproducts	1

Milk	0.04	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any cattle feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

Nectarine	4	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on nectarine.

Pear	1	Revoke	Bayer is voluntarily deleting this use.  SEQ CHAPTER \h \r 1

Pineapple, fresh	3	2	  SEQ CHAPTER \h \r 1 Re-evaluation of data from field trials shows lower residues are expected.

[Pineapple]

Poultry, fat	0.04

Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any poultry feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

Poultry, meat	0.04

Poultry, meat byproducts	0.04

Raspberry	2	Revoke	Bayer is voluntarily deleting this use.

40 CFR §180.410(c) A tolerance with regional registration is established for triadimefon and its metabolites in/on raspberries.

Sheep, fat	1	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on any sheep feed items.

40 CFR §180.6(a)(3) It is not possible to establish with certainty whether finite residues will be incurred but there is no reasonable expectation of finite residues.

Sheep, meat	1

Sheep, meat byproducts	1

Wheat, forage	15	Revoke	  SEQ CHAPTER \h \r 1 Currently, Bayer does not have any registered uses of triadimefon on wheat.

Wheat, grain	1

Wheat, milled fractions (except flour)	4

Wheat, straw	5

			b.	Codex Harmonization

  SEQ CHAPTER \h \r 1 No Codex maximum residue levels (MRLs) have been established for triadimefon.

The Codex Alimentarius Commission (Codex) has established several MRLs for triadimenol in/on various raw agricultural commodities.  The Codex MRLs are expressed in terms of triadimenol per se.  The MRLs have been established to accommodate triadimenol residues resulting from the use of triadimefon and/or triadimenol.  Compatibility cannot be achieved with the Codex MRLs because these levels are expressed in terms of triadimenol only; the U.S. tolerances for plant commodities are expressed in terms of triadimenol, KWG 1342, and KWG 1732 in/on cereal grains and cotton and triadimenol and KWG 1342 in/on bananas..

			c.	Residue Analytical Methods – Plants/Livestock

  SEQ CHAPTER \h \r 1 The reregistration requirements for residue analytical methods are fulfilled.  Adequate methods are available for data collection and for the enforcement of tolerances for residues of triadimefon  per se in/on plant commodities.  Since there is no reasonable expectation of residues in poultry, enforcement methods for the determination of triadimefon residues in livestock commodities are not needed.

Plant Commodities.  Two methods of gas chromatography with mass spectrometry detection (GC/MS) are listed in the Pesticide Analytical Manual (PAM Vol. II) for enforcement of tolerances in plant and livestock commodities.  The methods use a single moiety detection in which residues are converted to p-dichlorophenol, derivatized with dinitrofluorobenzene, and reported as triadimefon equivalents.  The GC/MS method is no longer adequate due to the recommended tolerance expression revisions.  However, a GC method using a nitrogen phosphorus detector (NPD; Report No. 80488) is available for determination of residues of triadimefon, triadimenol, KWG 1323, and KWG 1342, and it is adequate for the enforcement of a pineapple tolerance.  The reported method limit of quantitation (LOQ) is 0.01 ppm for each analyte.  The limit of detection (LOD) was not reported.

Livestock Commodities.  The Pesticide Analytical Manual (PAM) Vol. II lists the two GC/MS methods described above (Methods I and II) for the determination of triadimefon and its free and conjugated metabolites in livestock commodities.  Method I (Report No. 69531) is appropriate for livestock tissues and milk and Method II (Report No. 80265) is appropriate for livestock tissues and eggs.  The reported LOQ is 0.05 and the LOD is 0.01 ppm for both methods.

Multiresidue Methods.   The 10/99 FDA PESTDATA database (PAM Volume I, Appendix I) indicates that triadimefon is completely recovered (>80%) using Multiresidue Methods Section 302 (Luke Method; Protocol D); recovery of triadimefon is small (<50%) using Multiresidue Methods Sections 303 (Mills, Onley, and Gaither; Protocol E, nonfatty) and 304 (Mills, fatty food).  Triadimefon metabolites triadimenol and KWG 1323 are completely recovered using Section 302.  Triadimenol, KWG 1323, and metabolite KWG 1732 are not recovered using Sections 303 and 304.

		3.	Tolerance Summary for Triadimenol

	The current tolerance expression for residues of triadimenol resulting from direct application to primary crops is adequate.  The Agency has determined that the tolerance expression for residues in/on cereal grains (barley, corn, oats, rye, and wheat) and cotton commodities should include only triadimenol and its metabolites KWG 1342, and KWG 1732.  However, the tolerance expression for residues in/on bananas should include only triadimenol and its metabolite KWG 1342.  A summary of triadimenol tolerance reassessments is presented in Table 33.

			a.	Tolerances Currently Listed Under 40 CFR §180.450

Tolerances are established for residues of triadimenol and its butanediol metabolite, 4-(4-chlorophenoxy)-2,2-dimethyl-4-(1H-1,2,4-triazol-1-yl)-1,3-butanedio l (calculated as triadimenol) in/on various plant commodities.  The established tolerances in plant commodities range from 0.01 (sorghum grain and fodder) to 2.5 ppm (green forage of oats, rye, and wheat).  Tolerances are currently established for residues of triadimenol and its metabolites containing the chlorophenoxy moiety (calculated as triadimenol) in livestock commodities at 0.01 ppm (milk and poultry commodities) and 0.1 ppm (fat, meat, and meat byproducts of cattle, goats, hogs, horses, and sheep).

Tolerances Needed Under 40 CFR §180.450(a):

Triadimenol is registered for use on barley, corn, cotton, oats, rye, sorghum, wheat, and bananas as an import tolerance only; however, there are no existing tolerances associated with barley (hay), oat (hay), wheat (hay), and cotton (gin byproducts).  Therefore, tolerances will need to be established for these crops.

Tolerances Under 40 CFR §180.450(b):

The reregistration requirements for data depicting the magnitude of triadimenol residues of concern in meat, milk, poultry, and eggs have been fulfilled.  Acceptable ruminant and poultry feeding studies have been submitted and evaluated.  Triadimenol is not registered for use as a direct livestock treatment.  The nature of the residue in livestock is adequately defined for the current uses.  The Agency has concluded that the supported uses on barley, corn, cotton, oats, rye, and wheat result in a 40 CFR §180.6(a)(3) situation for ruminant commodities (i.e., there is no reasonable expectation of finite residues in ruminant commodities).  Therefore, additional data on the transfer of residues to meat, milk, poultry, and eggs are not required and all tolerances for triadimenol residues in livestock commodities should be revoked pending results from the requested corn and wheat metabolism studies.  If, however, foliar uses or registration on additional major livestock feed items are requested, then triazole and phenyl-labeled livestock metabolism studies would be required.  Such data may, in turn, trigger the need for magnitude of the residue (feeding) studies in livestock.

Table 33.  Tolerance Summary for Triadimenol

Commodity

Current Tolerance (ppm)

Tolerance Reassessment (ppm)

Comment/

[Correct Commodity Definition]

Tolerances Established Under 40 CFR §180.450(a)

Banana (Whole)1	0.2	0.2

	Barley, grain	0.05	TBD2

	Barley, straw	0.2	TBD2

	Corn, forage

0.05	TBD2	[Corn, field, forage]

[Corn, sweet, forage]

Corn, fresh (including sweet), (K+CWHR)

0.05	TBD2

[Corn, sweet, K+CWHR]

Corn, grain	0.05	TBD2	[Corn, field, grain]

[Corn, pop, grain]

Corn, stover	0.05	TBD2	[Corn, field, stover]

[Corn, pop, stover]

[Corn, sweet, stover]

Cotton, forage	0.02	Revoke	No longer considered a significant livestock feed item.

Cotton, undelinted seed	0.02	TBD2

	Oat, grain	0.05	TBD2

	Oat, forage	2.5	TBD2

	Oat, straw	0.2	TBD2

	Rye, forage	2.5	TBD2

	Rye, grain	0.05	TBD2

	Rye, straw	0.1	TBD2

	Sorghum, forage, hay	0.05	Revoke	Use is not being supported.

Sorghum, grain	0.01	Revoke	Use is not being supported.

Sorghum, grain, stover	0.01	Revoke	Use is not being supported.

Wheat, forage	2.5	TBD2

Wheat, grain	0.05	TBD2

Wheat, straw	0.2	TBD2

Tolerances Established Under 40 CFR §180.450(b)

Cattle, fat	0.1

Revoke	Available data indicate that tolerances for cattle commodities are not required.

Cattle, meat	0.1

Cattle, meat byproducts	0.1

Egg	0.01	Revoke	Available data indicate that a tolerance for egg is not required.

Goat, fat	0.1	Revoke	Available data indicate that tolerances for goat commodities are not required.

Goat, meat	0.1

Goat, meat byproducts	0.1

Hog, fat	0.1	Revoke	Available data indicate that tolerances for hog commodities are not required.

Hog, meat	0.1

Hog, meat byproducts	0.1

Horse, fat	0.1	Revoke	Available data indicate that tolerances for horse commodities are not required.

Horse, meat	0.1

Horse, meat byproducts	0.1

Milk	0.01	Revoke	Available data indicate that a tolerance for milk is not required.

Poultry, fat	0.01	Revoke	Available data indicate that tolerances for poultry commodities are not required.

Poultry, meat	0.01

Poultry, meat byproducts	0.01

Sheep, fat	0.1	Revoke	Available data indicate that tolerances for sheep commodities are not required.

Sheep, meat	0.1

Sheep, byproducts	0.1

Tolerances T Be Proposed Under 40 CFR §180.450(a)

Barley, hay

None established	TBD2

Cotton, gin byproducts	None established	TBD2

	Oat, hay	None established	TBD2

	Wheat, hay	None established	TBD2

	140 CFR §180.450(a) states that there are no U.S. registrations for bananas (whole).

2TBD = To be determined.  Additional data are required.  Note that while additional data are needed, there are no dietary risks associated with these tolerances and EPA considers them reassessed.

		D.	Regulatory Rationale under FIFRA

  SEQ CHAPTER \h \r 1 The Agency has determined that triadimefon is eligible for reregistration, in compliance with FIFRA, and the associated tolerances are considered reassessed, provided that:  1) required product-specific and generic data are submitted; 2) risk mitigation measures (including requests to delete certain uses) outlined in this document are adopted; and 3) label amendments are made to reflect these measures.  As stated above, the Agency will take steps to revoke the tolerances associated with the uses that are being deleted.

Risks for currently registered uses of triadimenol are below the Agency’s level of concern, and no further mitigation is required. The tolerances for triadimenol are considered reassessed.  Product-specific and generic data are required to be submitted, as specified in section V.

The following is a summary of the rationale for managing risks associated with the use of triadimefon.  Where labeling revisions are required, specific language is set forth in the summary tables of Chapter V of this document.

		 1.	Human Health Risk Management

Dietary (Food and Water) Risk Mitigation

	Bayer, the sole technical registrant, has agreed to voluntarily delete all triadimefon food uses, except for pre-plant and post-harvest use on pineapples. Food uses to be deleted include apples, pears, grapes, and raspberries (in both commercial and residential settings). In order to reduce potential drinking water exposure to triadimefon, use on turf will be restricted to golf courses and sod farms, only, with a maximum single application rate of 2.7 lbs ai/A, and a maximum yearly rate of 5.4 lbs ai/A.  With the above use deletions and restrictions, aggregate (food and water) risks are below the Agency’s level of concern.

			b.	Residential Risk Mitigation

	The following residential uses will remain as labeled use sites for triadimefon:

Outdoor ornamental flowers, shrubs, and trees;

Greenhouse ornamental flowers, shrubs, and trees.

Bayer, the sole technical registrant, has agreed to request voluntary deletions of the residential turf use to address post-application and aggregate risks to toddlers. In addition, a 17-day post-application, pre-harvest interval is required for sod farm turf, to address potential risks to toddlers exposed to sod farm turf transplanted to a residential setting.

In order to address risks to residential handlers making applications to ornamentals, the following mitigation measures are required:

Package all wettable powder products in water-soluble bags;

Prohibit application with hose-end sprayers in residential greenhouses;

Reduce the application rate for all outdoor ornamental applications to a maximum of 0.0025 lbs ai/gallon (for certain use sites, rates will remain lower than this maximum).

Currently, the number of applications that can be made to golf course turf is not specified on product labels.  Golf course use will be restricted to a maximum single application rate of 2.7 lbs ai/A, and a maximum yearly rate of 5.4 lbs ai/A.  Although aggregate risks to golfers (youths and adults) do not currently exceed the Agency’s level of concern, this mitigation measure will further reduce exposure to golfers.

Occupational Risk Mitigation

The following commercial and agricultural uses will remain as labeled use sites for triadimefon:

Golf course turf

Sod farm turf

Outdoor ornamental flowers, shrubs, and trees

Greenhouse ornamental flowers, shrubs, and trees

Roses

Azaleas, for control of pine-twisting rust only

Pines, including Christmas trees

Pine seedlings

Pine seed (in-nursery and commercial)

Pineapples (pre-plant and post-harvest dip)

Bayer, the sole registrant has requested that use on apples, pears, grapes, raspberries, and all turf other than golf course and sod farm turf be voluntarily deleted, reducing handler exposure.  For golf courses and sod farms, a maximum single application rate of 2.7 lbs ai/A, and a maximum yearly rate of 5.4 lbs ai/A are required, further reducing handler exposure.  Golf course applications will be restricted to turf less than 2.5 inches in height, which will limit application to golf course roughs.

In order to address risks to occupational handlers mixing, loading, and applying triadimefon, the mitigation listed below is required:

(1) Require all wettable powder products to be packaged in water-soluble bags (an engineering control).

(2) Require closed cockpits for aerial applications.

(3) Require chemical-resistant gloves for occupational handlers performing the following activities:

Mixing and loading all formulations (liquids, wettable powders, dry flowables)

Loading granulars;

Making applications with handheld equipment;

Any activities which involve contact with treated seed (including drying, raking, bagging, and sewing bags);

Mixing, loading, and applying when using a tree-injection unit;

Applying a ready-to-use briquette to pine seedlings.

(4) Require both chemical resistant gloves and a chemical resistant apron for occupational handlers performing the following activities:

Dipping pineapples (pre-plant, and post-harvest);

Dipping pine seed (for on-nursery applications).

With the above engineering controls and personal protective equipment, risks to residential handlers are below the Agency’s level of concern.

d.	Aggregate Risk Mitigation for Triazole Metabolites

	Acute, short- and intermediate-term, and chronic aggregate risks for degradates 1,2,4-triazole, triazole alanine, and triazole acetic acid are below the Agency’s level of concern.  The Agency considered the contribution of acute and chronic dietary risks from food and drinking water as well as residential handler and post-application exposures in the aggregate risk assessment for the free triazoles.  Therefore, no further mitigation is necessary at this time.

   SEQ CHAPTER \h \r 1 2.	Environmental Risk Mitigation

A number of the mitigation measures described above will reduce exposure and risks to mammals and birds.  These include:

Deleting all outdoor food uses of triadimefon (pears, apples, grapes, and raspberries);

Limiting turf application rates to a maximum single application rate of 2.7 lbs ai/A, and a maximum yearly rate of 5.4 lbs ai/A (reduced from no limit on the number of applications);

Prohibiting use on residential turf (only application to golf course and sod farm turf will continue);

Limiting golf course applications to turf that is less than 2.5 inches in height (this will reduce application to golf course roughs, which are usually 3 or more inches in height).

 3.	Other Labeling

  SEQ CHAPTER \h \r 1 In order to be eligible for reregistration, various use and safety information will be required in the labeling of all end-use products containing triadimefon.  For the specific labeling statements and a list of outstanding data, refer to Section V of this RED document.

 4.	Endangered Species Program

The Agency’s screening level ecological risk assessment for endangered species results in the determination that triadimefon will have no direct acute effects on threatened and endangered freshwater fish, and freshwater aquatic invertebrates.  However, the assessment indicates that triadimefon has the potential for causing acute risk to endangered birds, mammals, and non-vascular aquatic plants.  Chronic RQs for endangered mammals exceed the level of concern at all application rates modeled.  Chronic RQs for endangered birds also exceed the level of concern.  No data are available to assess the risks to estuarine/marine invertebrates, estuarine/marine fish, vascular aquatic plants, and terrestrial plants.  Therefore, risks cannot be precluded on these species at this time.

Further, potential indirect effects to any species dependent upon a species that experiences effect cannot be precluded from use of triadimefon.  These findings are based solely on EPA’s screening level assessment and do not constitute “may effect” findings under the Endangered Species Act.

  SEQ CHAPTER \h \r 1 The Agency has developed the Endangered Species Protection Program to identify pesticides whose use may cause adverse impacts on endangered and threatened species, and to implement mitigation measures that address these impacts.  The Endangered Species Act requires federal agencies to ensure that their actions are not likely to jeopardize listed species or adversely modify designated critical habitat.  To analyze the potential of registered pesticide uses that may affect any particular species, EPA uses basic toxicity and exposure data developed for the REDs and considers ecological parameters, pesticide use information, geographic relationship between specific pesticide uses and species locations, and biological requirements and behavioral aspects of the particular species.  This analysis will consider the risk mitigation measures that are being implemented as a result of this regulatory decision.

	Following this future species-specific analysis, a determination that there is a likelihood of potential impact to a listed species or its critical habitat may result in: limitations on the use of triadimefon; other measures to mitigate any potential impact; or consultations with the Fish and Wildlife Service or the National Marine Fisheries Service as necessary.  If the Agency determines that use of triadimefon “may affect” listed species or their designated critical habitat, EPA will employ the provisions in the Services regulations (50 CFR Part 402).  Until that species-specific analysis is completed, the risk mitigation measures being implemented through this RED will reduce the likelihood that endangered and threatened species may be exposed to triadimefon at levels of concern.  EPA is not requiring specific triadimefon label language at the present time relative to threatened and endangered species.  If, in the future, specific measures are necessary for the protection of listed species, the Agency will implement them through the Endangered Species Protection Program.

V.	What Registrants Need to Do

The use of currently registered products containing triadimefon in accordance with approved labeling will not pose unreasonable risks or adverse effects to humans or the environment provided that the risk mitigation measures and label changes (including use deletions) outlined in this document are implemented.  Therefore, all remaining uses of these products are eligible for reregistration.  These products will be reregistered once the required confirmatory generic data, product specific data, CSFs, and revised labeling are received and accepted by EPA.  Products that contain other ingredients in addition to triadimefon will be reregistered when all of their other active ingredients are also reregistered.

A.	  SEQ CHAPTER \h \r 1 For triadimefon technical grade active ingredient products, the registrant needs to submit the following items:

  SEQ CHAPTER \h \r 1 Within 90 days from receipt of the generic data call in (DCI):

	1.	Completed response forms to the generic DCI (i.e., DCI response form and requirements status and registrant’s response form); and

	2.	Any time extension and/or waiver requests with a full written justification.

Within the time limit specified in the generic DCI:

	1.	Citations of any existing generic data that address data requirements or submit new generic data responding to the DCI.

Please contact John W. Pates, Jr. at<PHONE_NUMBER> with questions regarding generic reregistration.

By U.S. Mail:					By express or courier service:

Document Processing Desk (DCI/SRRD)	Document Processing Desk (DCI/SRRD)

John W. Pates, Jr.				John W. Pates, Jr.

U.S. EPA (7508P)				Office of Pesticide Programs (7504P)

1200 Pennsylvania Ave., NW			  SEQ CHAPTER \h \r 1 Room S-4900

  SEQ CHAPTER \h \r 1 Washington, DC 20460			One Potomac Yard

  SEQ CHAPTER \h \r 1 					Arlington, VA 22202

  SEQ CHAPTER \h \r 1 For end-use products containing the active ingredient triadimefon, the registrant needs to submit the following items for each product:

Within 90 days from the receipt of the product-specific data call-in (PDCI):

(1) 	completed response forms to the PDCI (i.e., PDCI response form and requirements status and registrant’s response form); and

	(2)	any time extension or waiver requests with a full written justification.

	Within eight months from the receipt of the PDCI:

	(1)	two copies of the confidential statement of formula (EPA Form 8570-4);

a completed original application for reregistration (EPA Form 8570-1).  Indicate on the form that it is an “application for reregistration”;

five copies of the draft label, incorporating all label amendments outlined in Table 33 of this document;

a completed form certifying compliance with data compensation requirements (EPA Form 8570-34);

if applicable, a completed form certifying compliance with cost share offer requirements (EPA Form 8570-32); and

the product-specific data responding to the PDCI.

Please contact Veronica Dutch at<PHONE_NUMBER> with questions regarding product reregistration and/or the PDCI.  All materials submitted in response to the PDCI should be addressed:

By US mail:					By express or courier service only:

Document Processing Desk (PDCI/PRB)	Document Processing Desk (PDCI/PRB)

Veronica Dutch				Veronica Dutch

US EPA (7508P)				Office of Pesticide Programs (7504P)

1200 Pennsylvania Ave., NW			Room S-4900

Washington, DC 20460			One Potomac Yard

					Arlington, VA 22202

A.	Manufacturing Use Products

1.	Generic Data Requirements for Triadimefon

  SEQ CHAPTER \h \r 1 The generic data base supporting the reregistration of triadimefon for the above eligible uses has been reviewed and determined to be substantially complete.  However, the following data requirements are necessary to confirm the reregistration eligibility decision documented in this RED:

Human Health Effects

Guideline Study Name	New OPPTS Guideline No.	Old Guideline No.

Developmental Neurotoxicity Study (DNT)	870.6300	83-6

Ecological Effects

Guideline Study Name	New OPPTS Guideline No.	Old Guideline No.

Estuarine/Marine Mollusk EC50	850.1025	72-3 B

Estuarine/Marine Shrimp EC50	850.1035	72-3 C

Estuarine/Marine Fish LC50	850.1075	72-3 A

Seedling Emergence 	850.4225	123-1 A

Vegetative Vigor 	850.4250	123-1 B

Aquatic Vascular Plant Growth	850.4400	123-2

			2.	Labeling for Manufacturing-Use Products

  SEQ CHAPTER \h \r 1 To ensure compliance with FIFRA, manufacturing-use product (MUP) labeling should be revised to comply with all current EPA regulations, PR Notices, and applicable policies.  The MUP labeling should bear the labeling contained in the labeling table, which will be issued separately.

		B.	End-Use Products

			1.	Additional Product-Specific Data Requirements

  SEQ CHAPTER \h \r 1 Section 4(g)(2)(B) of FIFRA calls for the Agency to obtain any needed product-specific data regarding the pesticide after a determination of eligibility has been made.  The Registrant must review previous data submissions to ensure that they meet current EPA acceptance criteria and if not, commit to conduct new studies.  If a registrant believes that previously submitted data meet current testing standards, then the study MRID numbers should be cited according to the instructions in the Requirement Status and Registrants Response Form provided for each product.

A product-specific data call-in, outlining specific data requirements, accompanies this RED.

			2.	Labeling for End-Use Products

  SEQ CHAPTER \h \r 1 Labeling changes are necessary to implement measures outlined in Section IV above.  Specific language to incorporate these changes is specified in Table 34.

	C.	Data Requirements for Triadimenol

There are data that must be submitted to support the continuing registration of triadimenol.  These data are not expected to change the regulatory conclusions for triadimenol described in this document.  A generic DCI will be issued and will require development and submission of these listed data in order to confirm the conclusions outlined in this document.

Product Chemistry

Guideline Study Name	New OPPTS Guideline No.	Old Guideline No.

Stability	830.6313	63-13

pH ( H20 solutions)	830.7000	63-12

Ultraviolet/visible Absorption	830.7050	None

Partition Coefficient (N-octanol/water)	830.7550

830.7560

OR

830.7570

63-11

Water Solubility	830.7840

OR

830.7860

63-8

Residue Chemistry

Separate metabolism studies with triazole-14C and phenyl-14C labeled triadimenol applied as a seed treatment to wheat and corn must be conducted to confirm residues of concern.

Storage stability data for triadimenol, KWG 1342, and KWG 1732 in/on field corn, sweet corn, cotton, and wheat processed commodities are required pending the results from the requested metabolism studies.  Storage stability data for KWG 1732 in/ on wheat forage, hay, and straw are required pending the results from the requested metabolism studies.

Crop field trial data depicting residues of triadimenol, KWG 1342, and KWG 1732 in/on field corn (forage, grain, stover), sweet corn (forage, kernel plus cob with husks removed, grain, and stover), cotton (undelinted seed and gin byproducts), and wheat (forage, grain, hay, and straw) grown from seed treated at the maximum rate are required pending the results from the requested metabolism studies.

A wheat processing study conducted with triadimenol applied to wheat as a seed treatment should be submitted once the requested corn or wheat metabolism studies have been submitted and reviewed.

Limited field rotational crop studies for triadimenol must be submitted pending the results from the requested metabolism studies.

D.	Labeling Changes Summary Table

For triadimefon to be eligible for reregistration, all triadimefon labels must be amended to incorporate the risk mitigation measures outlined in Section IV.  Table 34 describes how language on the labels should be amended.

Table 34.  Labeling Changes Summary Table

Summary of Labeling Changes for Triadimefon

Description

Amended Labeling Language

Placement on Label

Manufacturing Use Products

One of these statements may be added to a label to allow reformulation of the product for a specific use or all additional uses supported by a formulator or user group

Only for formulation into a fungicide for the following use(s): golf course turfgrass, sodfarm turfgrass, outdoor- and greenhouse-grown ornamentals (trees, shrubs, flowering plants, including roses), azaleas (for control of pine-twisting rust only), pine trees (including Christmas trees), pine seedlings, pine seeds, and pineapple (preplant dip and postharvest dip only), “

“This product can not be formulated into end-use products with directions for use in residential or commercial settings on apples, grapes, pears, raspberries, azaleas (except to control pine-twisting rust only), or turfgrass (except for turfgrass on golf courses or sodfarms).”

“This product can not be formulated into liquid concentrate end-use products with directions for use on azaleas, pine seedlings, pine seeds, or pineapple.”

“This product can not be formulated into dry flowable end-use products with directions for use on pine trees, pine seedlings, or pineapple.”

“This product can be formulated into granular end-use products with directions for use only on golf course turfgrass or sodfarm turfgrass.”

Directions for Use

“This product may be used to formulate products for specific use(s) not listed on the MP label if the formulator, user group, or grower has complied with U.S. EPA submission requirements regarding support of such use(s).”

Directions for Use

Environmental Hazards

“Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in accordance with the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge.  Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage treatment plant authority.  For guidance, contact your State Water Board or Regional Office of the EPA.”

Precautionary Statements immediately following the User Safety Recommendations

End Use Products Intended for Occupational Use (WPS and NonWPS)

PPE Requirements Established by the RED1 for liquid concentrate end-use products

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] (on an EPA chemical-resistance category selection chart.”

“Mixers, loaders, applicators, flaggers, and other handlers must wear:

> Long sleeved shirt and long pants,

> Shoes plus socks, and

>Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials) when mixing/loading or when applying using handheld equipment or handheld nozzles.”

“See engineering controls for additional requirements.”

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

PPE Requirements Established by the RED1 for dry flowable end-use products

Note:  if the end-use product does not have directions for use as a seed treatment, then the phrase “or when handling treated seed (including spreading, drying, raking, bagging, and sewing seed bags)” may be dropped.

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] (on an EPA chemical-resistance category selection chart.”

“Mixers, loaders, applicators, flaggers, and other handlers must wear:

> Long sleeved shirt and long pants,

> Shoes plus socks, and

>Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials) when mixing/loading, when applying using handheld equipment or handheld nozzles, or when handling treated seed (including spreading, drying, raking, bagging, and sewing seed bags).”

“See engineering controls for additional requirements.”

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

PPE  Requirements Established by the RED1 for wettable powder end-use products

 Note: all wettable powder products must be in water soluble packets to be eligible for reregistration.

Note:  if the end-use product does not have directions for use as a seed treatment, then the phrase “or when handling treated seed (including spreading, drying, raking, bagging, and sewing seed bags)” may be dropped.

Note:  if the end-use product does not have directions for use as a dip treatment, then the phrases “participating in  dip applications” may be dropped.

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] (on an EPA chemical-resistance category selection chart.”

“Mixers, loaders, applicators, flaggers, and other handlers must wear:

> Long sleeved shirt and long pants,

> Shoes plus socks,

> Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials) when mixing/loading, when using handheld equipment or handheld nozzles, when participating in dip applications, or when handling treated seed (including spreading, drying, raking, bagging, and sewing seed bags), and

> Chemical-resistant apron, when mixing/loading, when participating in dip applications, or cleaning spills or equipment.”

“See engineering controls for additional requirements.”

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

PPE Requirements Established by the RED1 for granular products

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] (on an EPA chemical-resistance category selection chart.”

“Loaders, applicators, flaggers, and other handlers must wear:

> Long-sleeved shirt and long pants,

> Shoes plus socks, and

> Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials) when loading.”

“See engineering controls for additional requirements.”

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

PPE Requirements Established by the RED1 for ready-to-use briquette products

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] on an EPA chemical-resistance category selection chart.”

“Applicators and other handlers must wear:

> Long-sleeved shirt and long pants,

> Shoes plus socks, and

> Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials). “

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

PPE Requirements Established by the RED1 for tree-injection products

Note:  if the tree-injection product is ready-to-use, the words “mixers, loaders” may be dropped

“Personal Protective Equipment (PPE)”

“Some materials that are chemical-resistant to this product are (registrant inserts correct chemical-resistant material).  If you want more options, follow the instructions for category [registrant inserts A,B,C,D,E,F,G,or H] on an EPA chemical-resistance category selection chart.”

“Mixers, loaders, applicators and other handlers must wear:

> Long-sleeved shirt and long pants,

> Shoes plus socks, and

> Chemical resistant gloves, such as (registrant insert correct chemical-resistant materials).”

Immediately following/below

Precautionary Statements:  Hazards to Humans and Domestic Animals

User Safety Requirements

“Follow manufacturer's instructions for cleaning/maintaining PPE.  If no such instructions for washables exist, use detergent and hot water.  Keep and wash PPE separately from other laundry.”

“Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this product’s concentrate.  Do not reuse them.”

Precautionary Statements:  Hazards to Humans and Domestic Animals immediately following the PPE requirements

Engineering Controls for liquid, dry flowable , or granular formulations that contain directions for use for sodfarm turfgrass

“Engineering Controls”

“Pilots must use an enclosed cockpit in a manner that is consistent with the WPS for Agricultural Pesticides [40 CFR170.240(d)(6)]. Pilots must wear the PPE required on this labeling for applicators.”

Precautionary Statements:  Hazards to Humans and Domestic Animals   (Immediately following PPE and User Safety Requirements.)

Engineering Controls for wettable powders packaged in water-soluble packets.  All wettable powders must be in water soluble packets to be eligible for reregistration.

“Engineering Controls”

“Water soluble packets when used correctly qualify as a closed mixing/loading system under the Worker Protection Standard for Agricultural Pesticides [40 CFR 170.240(d)(4).  Mixers and loaders using water soluble packets must:

-wear the personal protective equipment required on this labeling for mixers and loaders, and

-be provided, have immediately available, and wear in an emergency, such as a broken package, spill, or equipment breakdown:

>chemical resistant footwear and

>a NIOSH-approved respirator equipped with:

-- a dust/mist filter with MSHA/NIOSH approval number prefix TC-21C or

-- any N, R, P, or HE filter.”

“Pilots must use an enclosed cockpit in a manner that is consistent with the WPS for Agricultural Pesticides [40 CFR170.240(d)(6)].  Pilots must wear the PPE required on this labeling for applicators.”

Precautionary Statements:  Hazards to Humans and Domestic Animals   (Immediately following PPE and User Safety Requirements.)

User Safety Recommendations

“User Safety Recommendations”

“Users should wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.”

“Users should remove clothing/PPE immediately if pesticide gets inside.  Then wash thoroughly and put on clean clothing.”

“Users should remove PPE immediately after handling this product.  Wash the outside of gloves before removing.  As soon as possible, wash thoroughly and change into clean clothing.”

Precautionary Statements under:  Hazards to Humans and Domestic Animals immediately following Engineering Controls

(Must be placed in a box.)

Environmental Hazards

“ ENVIRONMENTAL HAZARDS”

“Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean water mark.  Do not contaminate water when disposing of equipment washwater or rinsate.”

“Do not apply when weather conditions favor drift from treated areas.  Drift and runoff from treated areas may be hazardous to organisms in neighboring areas.”

“This product may contaminate water through runoff. This product has a high potential for runoff for several months or more after application. Poorly draining soils and soils with shallow water tables are more prone to produce runoff that contains this product.”

“This chemical has properties and characteristics associated with chemicals detected in ground water. The use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in ground water contamination.”

Environmental Hazards

Restricted-Entry Interval (for labels with WPS uses)

Note: the prohibition for sodfarms may be dropped if the end-use product does not contain directions for use on sodfarms

“Do not enter or allow worker entry into treated areas during the restricted entry interval (REI) of 12 hours.”

“Harvesting or transplanting turfgrass grown on sodfarms is prohibited for 17 days following application.”

Directions for Use, Agricultural Use Requirements Box

Early Reentry Personal Protective Equipment established by the RED (for labels with WPS uses)

“PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water, is:

> coveralls,

> shoes plus socks, and

> chemical-resistant gloves made of any waterproof material.”	Place in the Directions for Use In Agricultural Use Requirements box, immediately following the REI

Entry Restriction for NonWPS uses

Entry Restriction for non-WPS uses applied as a spray (does not include tree-injection uses):

“Do not enter or allow others to enter until sprays have dried.”

Entry Restriction for non-WPS uses applied dry (does not include ready-to-use briquette uses):

“Do not enter or allow others to enter until dusts have settled.”

Entry Restriction for non-WPS uses applied as a granular and when watering-in is required:

“Do not enter or allow others to enter the treated area (except those involved in watering-in) until watering-in is complete and the surface is dry.”

If no WPS uses on the label, place the statements in the Directions for Use Under General Precautions and Restrictions.

If WPS uses are also on the labeling, place these statements in a NonAgricultural Use Requirements box as specified in PR Notice 93-7 and 93-11.

General Application Restrictions (for labels with WPS uses)

“Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application.”

Place in the Directions for Use directly above the Agricultural Use Box.

Other Application Restrictions (Risk Mitigation)

All Products/Formulations Containing Triadimefon

Delete all directions for use for the following use-patterns:

> apples

> grapes

> pears

> raspberries

> residential or commercial turfgrass (except for turfgrass on golf courses or sodfarms).

Include the following statement: “Application to trees that bear fruit or nuts is prohibited.  Applications are permitted on nonbearing fruit or nut trees only.”

Directions for Use

Spray Drift

“Spray drift requirements”

(1)   SEQ CHAPTER \h \r 1 For groundbloom and aerial applications, use only medium or coarser spray nozzles according to ASABE (S572) definition for standard nozzles. Aerial applicators must consider flight speed and nozzle orientation in determining droplet size.

(2)   SEQ CHAPTER \h \r 1 Make aerial or ground applications when the wind velocity is 3 to 10 mph. Do not apply when the wind speed is greater than 10 mph. For all non-aerial applications, wind speed must be measured adjacent to the application site on the upwind side, immediately prior to application.

(4)   SEQ CHAPTER \h \r 1 Do not make aerial or ground applications into temperature inversions.

(5)   SEQ CHAPTER \h \r 1 For groundboom applications, apply with nozzle height no more than 4 feet above the ground or crop canopy.

(6) For airblast applications, turn off outward pointing nozzles at row ends and when spraying the outer two rows. To minimize spray loss over the top in tree applications, spray must be directed into the canopy.

(7) For aerial applications, do not release spray at a height greater than 10 feet above the ground or plant canopy.

(8) For aerial applications, the outermost nozzles must not exceed 60% of the wingspan or 80% of the rotor blade diameter.

(9)   SEQ CHAPTER \h \r 1 When aerial applications are made with a cross-wind, the swath will be displaced downwind.  The applicator must compensate for this displacement at the downwind edge of the application area by adjusting the path of the aircraft upwind.”

Application Restrictions for Turfgrass Uses

(Note: The maximum allowable application rate per application or per year must be listed as pounds or gallons of formulated product per acre, not solely as pounds active ingredient per acre.)

“Use on turfgrass is limited to sodfarm turf and golf course turf only.  Use on turfgrass is prohibited on all other residential and commercial sites.”

Maximum application rate is 2.7 lb ai/A

Maximum annual application rate is 5.4 lb ai/A

Minimum retreatment interval is 14 days.

“Aerial application and chemigation to turf are permitted on sodfarm turfgrass only.”

“Application to golf courses, including tees, greens, fairways, and roughs, is permitted only if the turfgrass is 2.5 inches or less in height.”

“Harvesting or transplanting turfgrass grown on sodfarms is prohibited for 17 days following application.”

Directions for Use associated with turfgrass use directions

Application Restrictions for Azaleas

“Use on azaleas is limited to applications to control pine-twisting rust disease.”

Directions for Use associated with azalea use directions

Application Restrictions for Ornamentals and Pine Trees, including Christmas trees

“Chemigation is permitted for use on ornamentals and pine trees, including Christmas trees.”

Application Restrictions for Ornamentals at Residential Sites

Note: The maximum allowable application rate must be listed as pounds or gallons of formulated product per acre, not solely as pounds active ingredient per gallon.)

“The maximum application rate for ornamentals (including azaleas) at residential sites is 0.0025 lb ai/gal.”

Directions for Use associated with ornamental use directions

End Use Products Intended Primarily for Use by Homeowners

Environmental Hazards

“ ENVIRONMENTAL HAZARDS”

“Do not apply directly to water. Do not contaminate water when disposing of equipment washwaters or rinsate.”

“Do not apply when weather conditions favor drift from treated areas.  Drift and runoff from treated areas may be hazardous to organisms in neighboring areas.”

“This product may contaminate water through runoff. This product has a high potential for runoff for several months or more after application. Poorly draining soils and soils with shallow water tables are more prone to produce runoff that contains this product.”

“This chemical has properties and characteristics associated with chemicals detected in ground water. The use of this chemical in areas where soils are permeable, particularly where the water table is shallow, may result in ground water contamination.”

Precautionary Statements

Application Restrictions

All products:

“Do not apply this product in a way that will contact any person or pet, either directly or through drift.  Keep people and pets out of the area during application.”

Directions for Use under General Precautions and Restrictions

Statements must be in the color red and in all caps.

Entry Restrictions

Products Applied as a Liquid (except tree-injection uses):

“Do not allow people or pets to enter the treated area until sprays have dried.”

Directions for Use under General Precautions and Restrictions

Directions for Use

“Do not apply this product to lawns or other turfgrass.”

Directions for Use section

Directions for Use on Ornamentals

Note: The maximum allowable application rate must be listed as pounds or gallons of formulated product per acre, not solely as pounds active ingredient per gallon.)

“Applications with hose-end sprayers are permitted only for outdoor use on ornamentals.  Use of hose-end sprayer equipment in residential greenhouses is prohibited.”

“The maximum application rate for ornamentals is 0.0025 lb ai/gal.”

Directions for Use section associated with the directions for ornamental uses

Other Application Restrictions (Risk Mitigation)

All Products/Formulations Containing Triadimefon

Delete all directions for use for the following use-patterns:

> apples

> grapes

> pears

> raspberries

> residential or commercial turfgrass

Include the following statement: “Application to trees that bear fruit or nuts is prohibited.  Applications are permitted on nonbearing fruit or nut trees only.”

Directions for Use

1 PPE that is established on the basis of Acute Toxicity of the end-use product must be compared to the active ingredient PPE in this document.  The more protective PPE must be placed in the product labeling.  For guidance on which PPE is considered more protective, see PR Notice 93-7.

2 The registrant must drop the N type filter from the respirator statement if the pesticide product contains or is used with oil.

Instructions in the Labeling section appearing in quotations represent the exact language that should appear on the label.

Instructions in the Labeling section not in quotes represents actions that the registrant should take to amend their labels or product registrations.

VI. AppendicesAppendix A:  Use Patterns Subject to Reregistration for Triadimefon

Site

Application Type

Application Timing

Application Equipment

	Formulation

Max. Single Application Rate

(ai)	Max. # Apps.	Minimum Retreatment Interval (Days)	Use Limitations

(Food Uses)

Pineapples (post-harvest or  pre-plant crowns)

Pre-plant and Post-harvest dip, spray

	WP	0.0028 lbs ai/gallon	1	Not Required; since only one application.

(NR)	All wettable powder products must be packaged in water soluble bags.

(Non-food Uses)

Azaleas (for control of pine twisting rust, only

Chemigation, groundboom, low-pressure handwand, high pressure handwand

	WP

DF	0.005 lbs ai/gallon	8	14	All wettable powder products must be packaged in water soluble bags.

Christmas trees

Aerial, flagging, airblast

	WP	0.25 lbs ai/A	8	14	A closed cockpit is required for aerial applications (all formulations).

All wettable powder products must be packaged in water soluble bags.

Golf Course Turf

Groundboom, LCO handgun, low-pressure handwand, and handgun sprayer

Flagging, tractor-drawn spreader

	LC

WP

DF

G	2.7 lbs ai/A	2

(at max. single app. rate)	14	Use is restricted to golf course and sod farm turf, only.

A maximum annual application rate of 5.4 lbs ai/A is allowed.

Applications are restricted to turf less than 2.5 inches in height.  This applies to the entire golf course, including tees, greens, fairways, and roughs.

All wettable powder products must be packaged in water soluble bags.

Greenhouse Ornamentals (including flowers, shrubs, and trees)

Low-pressure handwand, handgun sprayer, high-pressure handwand

	WP

LC	0.00625 lbs ai/gallon

0.00938 lbs ai/gallon

8

	14

14	Prohibit residential (consumer) hose-end sprayer applications in greenhouses.

All wettable powder products must be packaged in water soluble bags.

Ornamentals (including flowers, shrubs and trees)

Low-pressure handwand, handgun sprayer, high-pressure handwand

Low-pressure handwand, chemigation, groundboom, high-pressure handwand

	LC

WP

DF	0.0023 lbs ai/gallon

0.0025 lbs ai/gallon	8

	14

14	Residential (consumer) use limited to ornamentals, only.

Professional hose-end sprayer applications are allowed.

All wettable powder products must be packaged in water soluble bags.

Ornamentals (including shade trees and woody shrubs)

Tree injection unit (ready-to-use micro injection unit, or unit requiring product dilution)

	LC	0.000026 lbs ai/ inch of trunk circumference	6	NS

	Pines (including Christmas trees)

Low-pressure handwand and handgun sprayer

	LC	0.0023 lbs ai/gallon	8	14

	Pine Seed (on-nursery applications)

Dip

Planter box, hopper box, cement mixer,

Cement mixer

	WP

WP

DF	0.0000625 lbs ai/gallon

0.0013 lbs ai/A

0.00136 lbs ai/A	1

1

1	NR

NR

NR	All wettable powder products must be packaged in water soluble bags.

Pine Seed (commercial applications)

Commercial loading/applying, commercial bagging of treated seed, commercial bag sewing, and multiple commercial activities

	WP	0.0013 lbs ai/lb	1	NR	All wettable powder products must be packaged in water soluble bags.

Pine Seedlings

Aerial, flagging, airblast, groundboom, low-pressure handwand, handgun sprayer

By hand	WP

Ready-to-use briquette	0.5 lbs ai/A

0.000019 lbs ai/seedling	4

1	NR

NR	A closed cockpit is required for aerial application.

All wettable powder products must be packaged in water soluble bags.

Roses

Low-pressure handwand, handgun sprayer, high-pressure handwand

	LC

WP	0.00029 lbs ai/gallon	8	14	All wettable powder products must be packaged in water soluble bags.

Sod Farm Turf

Aerial, chemigation, flagging, groundboom, LCO handgun, low-pressure handwand, and handgun sprayer

Aerial, flagging, tractor-drawn spreader

	WP

DF

G	2.7 lbs ai/A	2

(at max. single app. rate)	17	A closed cockpit is required for aerial applications (all formulations).

A maximum annual application rate of 5.4 lbs ai/A is allowed.

All wettable powder products must be packaged in water soluble bags.

  SEQ CHAPTER \h \r 1 Appendix B.	Table of Generic Data Requirements and Studies Used to Make the Reregistration Decision

GUIDE TO APPENDIX B

	Appendix B contains listing of data requirements which support the reregistration for active ingredients within the case 2700 covered by this RED/TRED.  It contains generic data requirements that apply to triadimefon/triadimenol in all products, including data requirements for which a "typical formulation" is the test substance.

	The data table is organized in the following formats:

	1.	Data Requirement (Column 1).  The data requirements are listed in the order in which they appear in 40 CFR part 158.  The reference numbers accompanying each test refer to the test protocols set in the Pesticide Assessment Guidance, which are available from the National technical Information Service, 5285 Port Royal Road, Springfield, VA 22161<PHONE_NUMBER>.

	2.	Use Pattern (Column 2).  This column indicates the use patterns for which the data requirements apply.  The following letter designations are used for the given use patterns.

			A.	Terrestrial food

	 		B.	Terrestrial feed

			C.	Terrestrial non-food

			D.	Aquatic food

			E.	Aquatic non-food outdoor

			F.	Aquatic non-food industrial

			G.	Aquatic non-food residential

			H. 	Greenhouse food

			I.	Greenhouse non-food

			J.	Forestry

			K.	Residential

			L.	Indoor food

			M.	Indoor non-food

			N.	Indoor medical

			O.	Indoor residential

	3.	Bibliographic Citation (Column 3).  If the Agency has acceptable data in its files, this column list the identify number of each study.  This normally is the Master Record	 Identification (MIRD) number, but may be a "GS" number if no MRID number has been assigned.  Refer to the Bibliography appendix for a complete citation of the study.

APPENDIX B-1

Data Supporting Guideline Requirements for the Reregistration of Triadimefon

REQUIREMENT	USE PATTERN	CITATION(S)

                      PRODUCT CHEMISTRY

New Guideline Number	Old Guideline Number

	830.1550	61-1	Product Identity and Composition	All	CSF (’96)  SEQ CHAPTER \h \r 1

830.1600	61-2A	Start. Mat. & Mnfg. Process	All	00098119,   SEQ CHAPTER \h \r 1 42307801

830.1620	61-2B	Description of Production Process	All	00098119, 42307801

830.1650	61-2B	Description of Formulation Process	All	00098119, 42307801

830.1670	61-2B	Formation of Impurities	All	40477401

830.1700	62-1	Preliminary Analysis	All	00098120, 44166001

830.1750	62-2	Certification of limits	All	44166001, CSF (’96)

830.1800	62-3  	Enforcement Analytical Method	All	42307802

830.6302	63-2	Color	All	41616001

830.6303	63-3	Physical State	All	41616001

830.6304	63-4	Odor	All	41616001

830.6313	63-13	Stability to Normal and Elevated Temperatures, Metals and Metal Ions	All	42307803

830.6314	63-14	Oxidation/Reduction: Chemical Incompatibility	All	Not Applicable; N/A

830.6315	63-15	Flammability	All	N/A

830.6316	63-16	Explodability	All	N/A

830.6317	63-17	Storage Stability	All	N/A

830.6319	63-19	Miscibility	All	N/A

830.6320	63-20	Corrosion Characteristics	All	N/A

830.7000	63-12	pH	All	41616001

830.7050	None	UV/Visable Absorption	All	N/A

830.7100	63-18	Viscosity	All	41616001

830.7200	63-5	Melting Point	All	41616001

830.7220	63-6	Boiling Point	All	N/A

830.7300	63-7	Relative Density	All	41616001

830.7370	63-10	Dissociation Constants in Water	All	N/A

830.7550

830.7560 or

830.7570	63-11	Octanol/Water Partition Coefficient 	All	42307803

830.7840 or

830.7860	63-8	  SEQ CHAPTER \h \r 1 Water solubility:  column elution method; shake flask method	All

41616001

830.7950	63-9	Vapor Pressure	All	42307801

ECOLOGICAL EFFECTS

850.2100	71-1	Avian Acute Oral Toxicity

00071469, 41895901

850.2200	71-2A	Avian Dietary Toxicity - Quail

00071469, 00050066

850.2200	71-2B	Avian Dietary Toxicity - Duck

00126277

850.2300	71-4	Avian Reproduction –Avian chronic tests on the Mallard Duck and Bobwhite Quail

00110430, 00110431, 40283102, 42342301

850.2400	71-3	Mammal Acute/ Chronic Toxicity- Rat

00125411, 00151248, 00155075, 00264276, 92188019, 92188320

850.1010	72-2A	Invertebrate Toxicity

00071469, 00231311, 254693, 41922101

850.1025	72-3B	Estuarine/Marine Toxicity - Mollusk

Data Gap

850.1035

850.1045	72-3C	Estuarine/Marine Toxicity – Shrimp EC50

Data Gap

850.1075	72-3A	Estuarine/Marine Fish LC50

Data Gap

850.1075	72-1A	Fish Toxicity- Bluegill

00071469, 43304301

850.1075	72-1C	Fish Toxicity- Rainbow Trout

00071469, 43256201

850.1300	72-4A	Freshwater Fish- Early Life Stage

00251243, 41922103

850.1500	72-5 	Life Cycle Fish

N/A

850.1735	None	Freshwater Acute InvertebrateToxicity

00071469, 00231311, 00246736,  41922102

850.4100	122-1A	Terrestrial Toxicity; Seedling Emergence

N/A

850.4150	122-1B	Terrestrial Plant Toxicity; Vegetative Vigor

N/A

850.5400	122-2	Aquatic Plant Growth

00159558, 00266051

850.4225	123-1A	Seed Germination and Seedling Emergence (Tier 2)

Data Gap

850.4250	123-1B	Vegetative Vigor (Tier 2)

Data Gap

850.4400	123-2	Aquatic Vascular Plant Growth (Tier2)

Data Gap

850.3020	141-1	Honey Bee Acute Contact

05001991, 42307804

850.3030	141-2	Honey Bee Residue on Foliage

N/A

	          TOXICOLOGY

870.1100	81-1	Acute Oral Toxicity

00125411, 00264276, 43936101

870.1200	81-2	Acute Dermal Toxicity-Rat

00145086, 00264276

870.1300	81-3	Acute Inhalation Toxicity-Rat

41616002

870.2400	81-4	Primary Eye Irritation-Rabbit

41782501

870.2500	81-5	Primary Skin Irritation- Rabbit

41616004

870.2600	81-6	Dermal Sensitization- Guinea pig

41554001

870.6100	82-5A	90-Day Neurotoxicity- Hen

44153501

870.6300	83-6	Developmental Neurotoxicity Study

00089023; Data Gap

870.3100	82-1A	90-Day Feeding - Rat

00048624

870.3100	82-1A	30-Day Oral Toxicity- Rat

00048627

870.3150	82-1B	90-Day Feeding (Non-rodent)- Dog

00048625, 00060226

870.3200	82-2	21-Day Dermal Toxicity- Rat

42341501

870.3700	83-3A	Developmental Toxicity - Rat

00089023, 00149336, 92188018

870.3700	83-3B	Developmental Toxicity - Rabbit

41446201, 42089601

870.3800	83-4	2-Generation Reproduction - Rat

00155075, 92188019, 92188020

The reproductive study in the rat is acceptable/ non-guideline in conjunction with the 3-generation study (MRID 00032541)

870.3800	83-4	Reproduction and fertility effects (3-Gen)- Rat

00032541

The reproductive study in the rat is acceptable/ non-guideline in conjunction with the multi-generation reproduction study (MRID 00155075)

870.4100	83-1B	Chronic Toxicity - Dog

00032539, 00126261

870.4200	83-2B	Carcinogenicity- Mice

40752101, 40865101

870.4300	83-5	2-year Combined Chronic/Oncogenicty- Rat

42153901

870.5100	84-2	Mutagenicity-Gene Mutation- bacterial

00126264, 00099413

870.5395	84-2	Micronuleus Assay

00048637

870.5450	84-2	Cytogenetics Dominant Lethal Assay

00048628

870.5550	84-2	Unscheduled DNA Synthesis Assay

00159343

870.6200	81-8	Acute Neurotoxicity Screening Battery-Rat

43495509, 43936101

870.6200	82-7	Subchronic Neurotoxicity Screening Battery- Rat

44153501

870.7485	85-1	General Metabolism- Rat

00033057, 42409101

OCCUPATIONAL/RESIDENTIAL EXPOSURE

875.2400	133-3	Dermal Passive Dosimetry Exposure

43125401

875.2500	133-4	Inhalation Passive Dosimetry Exposure

43125401

None	231	Estimation of Dermal Exposure at Outdoor Sites

45654503

None	232	Estimation of Inhalation Exposure at Outdoor Sites

45654503

ENVIRONMENTAL FATE

None	160-5	Chemical Identity

N/A

835.2120	161-1	Hydrolysis

41922101

835.2240	161-2	Photodegradation - Water

42112901

835.2410	161-3	Photodegradation - Soil

00044169, 42820401

835.2370	161-4	Photodegradation - Air

N/A

835.4100	162-1	Aerobic Soil Metabolism

42242701, 42224104, 41686102,

835.4200	162-2	Anaerobic Soil Metabolism

41686101, 42401201

835.4400	162-3	Anaerobic Aquatic Metabolism

41686101, 42401201

835.4300	162-4	Aerobic Aquatic Metabolism

42224104

835.1240	163-1	Leaching/Adsorption/Desorption

41616008, 42356601

835.1410	163-2	Laboratory Volatilization

N/A

835.8100	163-3 	Volatility- Field

N/A

835.6100	164-1	Terrestrial Field Dissipation

42242701, 41686103, 41686104

835.6200	164-2	Aquatic Field Dissipation

N/A

835.6300	164-3	Forestry Dissipation

N/A

860.1950	165-4	Bioaccumulation in Fish

41619901

None	165-5	Bioaccumulation- Aquatic Nontarget

41619901

835-7100	166-1	Ground Water- Small Scale Prospective

N/A

840.1100	201-1	Spray Droplet Size Spectrum

N/A

840.1000	201-4	Background for Pesticide Aerial Drift (Evaluation)

N/A

840.1200	202-1	Spray Drift Field Deposition (Evaluation)

N/A

RESIDUE CHEMISTRY

860.1200	171-3	Directions for Use

N/A

860.1300	171-4A	Nature of Residue - Plants

42123401, 42123402, 42123403, 42798901, 42853401, 92188025-33

860.1300	171-4B	Nature of Residue - Livestock

42123404, 42856801, 42864901, 43418301-02, 92188034-39

860.1340	171-4C	Residue Analytical Method - Plants

43870101, 44041002, 92188040-43

860.1340	171-4D	Residue Analytical Method - Livestock

43418303, 92188044-48

860.1360	171-4M	Multiresidue Methods

41976601, 43705401

860.1380	171-4E	Storage Stability Data- Plant and Livestock

41976602, 42857401, 44038901, 44041001, 92188051-53, 43462401

860.1480	171-4J	Magnitude of Residues -Meat/Milk/Poultry /Egg

92188054-57

860.1500	171-4K	Crop Field Trials

92188060-65, 92188070, 92188073-75, 42342303-08,  41809401

860.1520	171-4L	Magnitude of Residue in Processed Food/Feed

42346601, 43948601, 92188064-65, 92188069, 43284401, 42013201, 92188074

860.1850	165-1	Confined Accumulation in Rotational Crops Study

42613301

860.1900	165-2	Field Accumulation in Rotational Crops Study

N/A

APPENDIX B-2

Data Supporting Guideline Requirements for the Reregistration of Triadimenol

REQUIREMENT	USE PATTERN	CITATION(S)

                      PRODUCT CHEMISTRY

New Guideline Number	Old Guideline Number

	830.1550	61-1	Product Identity and Composition	All	N/A

830.1600	61-2A	Start. Mat. & Mnfg. Process	All	N/A

830.1620	61-2B	Description of Production Process	All	N/A

830.1650	61-2B	Description of Formulation Process	All	N/A

830.1670	61-2B	Formation of Impurities	All	N/A

830.1700	62-1	Preliminary Analysis	All	N/A

830.1750	62-2	Certification of limits	All	N/A

830.1800	62-3  	Enforcement Analytical Method	All	N/A

830.6302	63-2	Color	All	N/A

830.6303	63-3	Physical State	All	N/A

830.6304	63-4	Odor	All	N/A

830.6313	63-13	Stability to Normal and Elevated Temperatures, Metals and Metal Ions	All	Data Gap

830.6314	63-14	Oxidation/Reduction: Chemical Incompatibility	All	N/A

830.6315	63-15	Flammability	All	N/A

830.6316	63-16	Explodability	All	N/A

830.6317	63-17	Storage Stability	All	N/A

830.6319	63-19	Miscibility	All	N/A

830.6320	63-20	Corrosion Characteristics	All	N/A

830.7000	63-12	pH	All	Not available; Data Gap

830.7050	None	UV/Visable Absorption	All	Not Available; Data Gap

830.7100	63-18	Viscosity	All	N/A

830.7200	63-5	Melting Point	All	00125399

830.7220	63-6	Boiling Point	All	N/A

830.7300	63-7	Relative Density	All	00125399

830.7370	63-10	Dissociation Constants in Water	All	Not available

830.7550

830.7560 or

830.7570	63-11	Octanol/Water Partition Coefficient 	All	Not available; Data Gap

830.7840 or

830.7860	63-8	  SEQ CHAPTER \h \r 1 Water solubility:  column elution method; shake flask method	All

00125399; Data Gap

830.7950	63-9	Vapor Pressure	All	00125399

	          TOXICOLOGY

870.1100	81-1	Acute Oral Toxicity

00125411

870.1200	81-2	Acute Dermal Toxicity-Rat

00145086

870.1300	81-3	Acute Inhalation Toxicity-Rat

00145087

870.2400	81-4	Primary Eye Irritation-Rabbit

00145088

870.2500	81-5	Primary Skin Irritation- Rabbit

00145088

870.2600	81-6	Dermal Sensitization- Guinea pig

00125413

870.3100	82-1A	90-Day Oral Toxicity- Rat

00127769, 42192701

870.3150	82-1B	90-Day Oral Toxicity (Non-rodent )- Dog

00125420

870.3150	82-1B	6 months oral toxicity (Non-rodent)- Dog

00151247

870.3200	82-2	15-Day Dermal Toxicity- Rabbit

00151246

870.3465	82-4	21-Day Inhalation Toxicity- Rat

00125421

870.3700	83-3A	Prenatal Developmental Toxicity - Rat

40307804, 40887702, 41498401

870.3700	83-3B	Developmental Toxicity - Rabbit

40307805, 40887703, 42365001

870.3800	83-4	2-Gen. reproduction and fertility effects - Rat

00151248

870.4100	83-1B	Chronic Toxicity - Dog

00150484, 00159012

870.4200	83-2B	Carcinogenicity- Mice

00126259, 44740901

870.4300	83-5	Combined Chronic/Carcinogenicity- Rat

00126260

870.5100	84-2	Bacterial system, mammalian activation-Gene Mutation

00126264

870.5300	84-2	In Vitro Mammalian Cell Gene Mutation

00126269

870.5450	84-2	Cytogenetics Dominant Lethal Assay

00126266

870.5500	84-2	Other Genotoxicity DNA Damage

00126271

870.5550	84-2	Other Genotoxicity Unscheduled DNA Synthesis

00126271

870.5900	84-2	Other Effects In Vitro Sister Chromatid Exchange Assay

40815901

870.6100	81-7	Acute Neurotoxicity Study

Data Gap

870.6200	82-7	Subchronic Neurotoxicity Study

Data Gap

Other	none	Other Studies; Central Nervous Effects- Mice

00145083

RESIDUE CHEMISTRY

860.1200	171-3	Directions for Use

N/A

860.1300	171-4A	Nature of Residue - Plants

42123401-03, 42798901, 42853401, 92188025-33

860.1300	171-4B	Nature of Residue - Livestock

42123404, 42856801, 42864901, 43418301-02, 92188034-39

860.1340	171-4C	Residue Analytical Method - Plants

43870101, 44041002, 92188040-43

860.1340	171-4D	Residue Analytical Method - Livestock

43418303, 92188044-48

860.1360	171-4M	Multiresidue Methods

40969801, 41976601, 43705401

860.1380	171-4E	Storage Stability Data- Plant and Livestock

41976602, 42857401, 44038901, 44041001, 92188051-53, 43462401

860.1480	171-4J	Magnitude of Residues -Meat/Milk/Poultry /Egg

92188054-57

860.1500	171-4K	Crop Field Trials

00125407-09, 40615201, 41051401, 41242801, 42696308-09, 42712101

860.1520	171-4L	Magnitude of Residue in Processed Food/Feed

44519801-03

860.1850	165-1	Confined Accumulation in Rotational Crops Study

42613301

860.1900	165-2	Field Accumulation in Rotational Crops Study

N/A

Appendix C.  Technical Support Documents

	Additional documentation in support of this RED is maintained in the OPP docket, located in Room 119, Crystal Mall #2, 1801 South Bell Street, Arlington, VA.  It is open Monday through Friday, excluding Federal Holidays, from 8:30 am to 4 pm.

	The docket contains the risk assessments and related documents as of August 30, 2006.  The availability announcement will be published in the Federal Register.  All documents, in hard copy form, may be viewed in the OPP docket room or downloaded or viewed via the internet at the following site:   HYPERLINK "http://www.epa.gov/pesticides/reregistration"  www.epa.gov/pesticides/reregistration .  The following list details all documents related to the Triadimefon/Triadimenol (RED/TRED).

Health Effects Documents:

DP Barcode 329823 and D328572.  Jin Kim, Tara Chandgoyal and Jonathan Becker.  July 18, 2006.  Characterization of Triadimefon Use on Golf Courses, Turf, Pine Seed and Seedling Treatment, and Pineapple.

DP Barcode D314778.  Yvonne Barnes and Sheila Piper.  July 6, 2006.  Triadimefon: Revised Acute, Probabilistic and Chronic Dietary (Food + Drinking Water) Exposure and Risk Assessments for the Triadimefon Reregistration.

DP Barcode D331455.  Yvonne Barnes and Sheila Piper.  August 1, 2006. Triadimefon + Triadimenol:  Aggregate Acute, Chronic, and Short-Term Risk Assessments Reflecting July, 2006 Risk Mitigation in Response to the Phase 4 Triadimefon RED.

5.   	DP Barcode D328262.  Rich Griffin.    SEQ CHAPTER \h \r 1 June 20, 2006.  Triadimefon:  HED Response to Comments Received During the Public Comment Phase.

6.	DP Barcode D330611.  Rich Griffin.  July 10, 2006.  Triadimefon/Triadimenol: Summary of Refinements and Revisions to the Human Health Risk Assessment.

7.	DP Barcode D314814 and D315040.  Shanna Recore.  June 30, 2006. Triadimefon: Occupational and Residential Exposure Assessment for the Reregistration Eligibility Decision Document.

8.	Meeting Summary.  Kimberly Nesci.  EPA/FDA Joint Teleconfernce on July 11, 2006 to Discuss 1,2,4 Triazole (Free Triazole) as a Common Metabolite of Triazole Derivative Fungicides and Anastrozole, a Drug.

 Sam Ary.  Triadimefon. Acute and Chronic Dietary Exposure Assessments for the Reregistration Eligibility Decision (RED) Document.

10.	 DP Barcode D321636.  Sam Ary.  August 31, 2005.  Triadimefon. Registrants Response to Residue Chemistry Data Requirements.  Magnitude of Triadimefon Residues of Concern in Apple Processed Commodities.

11.	 DP Barcode D314778.  Sam Ary.  November 23, 2005.  Triadimefon.  Acute and Chronic Dietary Exposure Assessments for the Reregistration Eligibility Decision (RED) Document.

12.	 DP Barcode D315115.  Yvonne Barnes.  November 22, 2005.  Triadimefon: 	 Summary of Product Chemistry Data for Reregistration Eligibility Decision 	 (RED) Document.

13.	 DP Barcode D 326678.  Rich Griffin.  February 9, 2006.  Triadimefon. 	 	 Preliminary Human Health Risk Assessment (Revised).

14.	 DP Barcode D314742.  Sam Ary.  November 23, 2005.  Triadimefon.  Summary of Analytical Chemistry and Residue Data for the Reregistration Eligibility Decision (RED) Document.

15.	 DP Barcode D314928.  Sam Ary.  November 18, 2005.  Triadimenol Acute 	 and Chronic Dietary Exposure Assessments for the Tolerance Reassessment 	 Eligibility Decision Document.

16.	 DP Barcode D314891.  Sam Ary.  November 17, 2005.  Triadimenol. 	 	 Summary of Analytical Chemistry and Residue Data for the Tolerance 	 	 Reassessment Eligibility Decision Document.

 DP Barcode D326716.  Christina Jarvis.  January 24, 2006.  Triadimenol HED Chapter of the Tolerance Reassessment Eligibility Decision Document    (Revised).

 DP Barcode D322336.  Sam Ary.  October 14, 2005.  Triadimenol.   Registrants Response to Residue Chemistry Data Requirements.

 DP Barcode D315152.  Yvonne Barnes.  November 22, 2005.  Summary of Product Chemistry Data for Tolerance Reassessment Document.

 DP Barcode D322240.  Jack Arthur.  December 9, 2005.  Occupational and Residential Exposure/Risk Assessment of 1,2,4-Triazole.

 DP Barcode D 322238.  Michael Doherty.  November 1, 2005.  1,2,4-Triazole. Acute and Chronic Dietary Exposure Assessments to Support Reregistration and Registration Actions for Triazole-derivative Fungicides.

 DP Barcode D322239.  Michael Doherty.  December 20, 2005.  Triazole Alanine and Triazole Acetic Acid.  Acute and Chronic Dietary Exposure Assessments to Support Reregistration and Registration Actions for Triazole-derivative Fungicides.

 DP Barcode D322215.  Michael Doherty.  February 7, 2006.  1,2,4-Triazole, Triazole Alanine, triazole Acetic Acid:  Human Health Aggregate Risk Assessment in Support of Reregistration and Registration Actions for Triazole-derivative Fungicide Compounds.

  Kathleen Raffaele.  Triazoles- 2nd Report of the Ad Hoc HED Peer Review Committee.

Ecological Fate and Effects Documents:

DP Barcode D328531.  Fred Jenkins and Jonathan Angier.  June 1, 2006.  Response to Bayer Public Comments Regarding the Environmental Fate and Effects Division Triadimefon Risk Assessment.

DP Barcode D 331725.  Fred Jenkins and Jonathan Angier.  August 3, 2006.  EFED Revisions to the Ecological Risk Assessment (dated Aug. 30, 2005) and the Drinking Water Exposure Assessment (dated Aug. 31, 2005) in Support of the Triadimefon Reregistration Eligibility Decision Document.

	DP Barcode D316941.  Jonathan Angier.  August 31, 2005.  Tier 2 Drinking 	Water Assessment for Triadimefon and its Major Degradate Triadimenol.

	Jonathan Angier and Michelle Embry.  January 19, 2006.  Environmental Fate 	and Ecological Risk Assessment for Triadimefon.

	DP Barcode D312519.  James Breithaupt.  February 9, 2005.  TRED for  Triadimenol; Drinking Water Assessment.

	6.	DP Barcode D329271.  James Hetrick.  June 15, 2006. Response to Triazole 		Task Force Comments on the FQPA Drinking Water Assessment for 1,2,4-		Triazole (1,2,4-T), Triazole alanine (TA), and Triazole acetic acid (TAA).

Other Documents:

	1.	Memorandum.  John A. Lazor.  EPA 1,2,4 Triazole Consult Response.   Appendix D.  Citations Considered to be Part of the Data Base Supporting the Reregistration Eligibility Decision (Bibliography) for Triadimefon and Triadimenol

Bibliography

MRID	Citation Reference

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32541	Loser, E.; Lorke, D. (1979) Meb 6447 Multigeneration Reproduction Study on Rats: Report No. 8297; Report No. 67752. (Unpublished study received Apr 28, 1980 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL: 099413-F)

33057	Fredrickson, D.R. (1978) Metabolism of Bayleton^(TM)I in Rats: Re- port No. 66201. (Unpublished study received Apr 28, 1980 under 3125-318; submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:099415-F)

48624	Mohr, U. (1976) Meb 6447: Subchronic Toxicity Study on Rats (Twelve -Week Feeding Experiment): Report No. R 840 a; Report No. 44300. (Unpublished study received Aug 15, 1977 under 3125-318; pre- pared by Medizinische Hochschule Hannover, Abteilung fur Experi- mentelle Pathologie, West Germany, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:231312-C)

48625	Hoffman, K.; Luckhaus, G. (1974) Meb 6447: Subchronic Toxicity Study on Dogs (Thirteen-Week Feeding Experiment): Report No. 5071; Report No. 44737. (Unpublished study received Aug 15, 1977 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:231312-D)

48627	Thyssen, J.; Kimmerle, G.; Luckhaus, G. (1974) Meb 6447: Subacute Toxicity Studies: Report No. 4464; Report No. 46338. (Unpub- lished study received Aug 15, 1977 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp.; Kansas City, Mo.; CDL:231312-F)

48628	Machemer, L. (1976) Meb 6447: Dominant Lethal Study on Male Mice to Test for Mutagenic Effects: Report No. 5837; Report No. 47929. (Unpublished study received Aug 15, 1977 under 3125-318; pre- pared by Bayer, AG, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:231312-G)

48637	Machemer, L. (1977) MEB 6447 (Triadimefon, Bayleton Active Ingre- dient): Micronucleus Test on Mice to Evaluate Meb 6447 for Muta- genic Effects: Report No. 6622; Report No. 52724. (Unpublished study received Aug 15, 1977 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL: 231312-P)

50066	Fink, R.; Beavers, J.B. (1977) Final Report: Eight-Day Dietary LC50--Bobwhite Quail: Project No. 149-105; Report No. 527773. (Unpublished study received Aug 15, 1977 under 3125-318; pre- pared by Wildlife International, Ltd., submitted by Mobay Chemi- cal Corp., Kansas City, Mo.; CDL:231311-K)

60226	Hoffmann, K.; Luckhaus, G.; Lorke, D. (1974) Meb 6447: Subchronic Toxicity Study on Dogs (Thirteen-Week Feeding Experiment): Re- port No.5071; Report No. 44737. (Unpublished study received Dec 15, 1977 under 3125-EX-149; prepared by Bayer, AG, W. Germany, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL: 232490-D)

71469	Mobay Chemical Corporation Agricultural Chemicals Division; Environmental Toxicology of Baytan (Triadimenol); KWG 0519; October 29, 1982.

89023	Nagumo, K.; Teraki, Y.; Chiba, T.; et al. (1981) Teratogenicity Test of MEB 6447 in Pregnant Rats: ?Submitter| 80257. (Unpub- lished study received Jan 5, 1982 under 1F2474; prepared by St. Marianna Univ., First Dept. of Anatomy, Laboratory of Embry- ology, submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL: 070570-A)

98119	Smith, D.N. (1981) Bayleton Manufacture. (Unpublished study re- ceived Mar 30, 1982 under 2F2665; submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:070747-A)

98120	Harbin, D.N.; Slahck, S.C.; Westphal, C. (1982) The Composition of Technical ^(R)IBayleton: Report No. 80605. (Unpublished study received Mar 30, 1982 under 2F2665; submitted by Mobay Chemical Corp., Kansas City, Mo.; CDL:070747-B)

110430	Mobay Chemical Corp. (1982) Synopsis of Environmental Toxicology of Bayleton. Summary of studies 248117-B through 248117-E. (Unpublished study received Aug 17, 1982 under 3125-318; CDL: 248117-A)

110431	Lamb, D.; Carsel, M.; Mallicoat, D.; et al. (1982) Triadimefon (Bayleton) Reproduction Study with Bobwhite Quail: Study No. 81- 675-03; 80753. (Unpublished study received Aug 17, 1982 under 3125-318; submitted by Mobay Chemical Corp., Kansas City, MO; CDL:248117-B)

125399	Mobay Chemical Corp. (1983) Product Chemistry of Baytan. (Compi- lation; unpublished study received Mar 11, 1983 under 3125-346; CDL:071461-A)

125411	Mihail, F.; Thyssen, J.; Lorke, D. (1980) KWG 0519 (Triadimenol): Acute Toxicity Studies--(Isomer Ratio 80:20): Bayer Report No. 9451; 69378. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Farbenfabriken Bayer, AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL: 071466-B)

125421	Kimmerle, G.; Lorke, D. (1976) KWG 0519: Subacute Inhalation Toxicity Study on Rats: Report No. 6321; 51130. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Farben- fabriken Bayer, AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071466-M)

126259	Bomhard, E.; Loser, E.; Frank; et al. (1982) KWG 0519 (Triadimenol, Baytan Active Ingredient): Chronic Toxicological Study on Mice (Feeding Experiment over Two Years): Report No. 10855- 82291. (Unpublished study received Mar 11, 1983 under 3125- 346; prepared by Farbenfabriken Bayer, AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071467-A)

126260	Kroetlinger, F.; Loeser, E.; Schilde, B.; et al. (1982) KWG 0519: (Triadimenol, the Active Ingredient of Baytan): Chronic Toxicity Study on Rats (2-year Feeding Experiment): Bayer Report No. 11009; 82358. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Bayer AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071468-A)

126261	Hoffmann, K.; Groning, P.; Lorke, D. (1978) MEB 6447: Long-term Toxicity Study on Dogs (Two-year Feeding Study): Report No. 7882; 66656. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Bayer AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071468-B)

126264	Herbold, B.; Lorke, D. (1979) KWG 0519: Salmonella/Microsome Test for Detection of Point-mutagenic Effects: Report No. 8189; 67595. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Bayer AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071468-F)

126266	Herbold, B.; Lorke, D. (1978) KWG 0519: Dominant Lethal Study on Male Mouse to Test for Mutagenic Effects: Report No. 7900; 66746. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Bayer AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071468-H)

126269	Cifone, M.; Balinas, V. (1982) Mutagenicity Evaluation of KWG 0519 in the Mouse Lymphoma Forward-mutation Assay: LBI Safety No. 7607; 82353. Final rept. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Litton Bionetics, Inc., submitted by Mobay Chemical Corp., Kansas City, MO; CDL: 071468-K)

126271	Herbold, B.; Lorke, D. (1981) KWG 0519: Triadimenol, the Active Ingredient of Baytan: Study of DNA Damage Using the E. coli Pol Al- Test: Bayer Report No. 10265; 80212. (Unpublished study received Mar 11, 1983 under 3125-346; prepared by Bayer AG, W. Ger., submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071468-M)

126277	Lamb, D.; Toll, P.; Mallicoat, D.; et al. (1981) Acute Dietary LC50 of Technical Triadimenol (Baytan) to Mallard Ducks and Bobwhite Quail: Study No. 80-175-09 and 80-175-05. (Unpublished study received Mar 11, 1983 under 3125-346; submitted by Mobay Chemical Corp., Kansas City, MO; CDL:071469-F)

145083	Polacek, I. (1983) Central Nervous Effects of KWG 0519 (Pilot Study): Study No. 03018. Unpublished study prepared by Toxicol- ogical Institute Regensburg. 17 p.

145086	Hixson, E. (1983) Acute Dermal Toxicity of Baytan 25% Dry Flowable in Rabbits: Study Number 83-023-05. Unpublished study prepared by Mobay Chemical Corporation. 11 p.

145087	Sangha, G. (1983) Acute Inhalation Toxicity Study with Baytan 25% Dry Flowable in Rats: Study Number 83-041-08. Unpublished study prepared by Mobay Chemical Corporation. 16 p.

145088	Hixson, E. (1984) Eye and Dermal Irritation of Baytan 25% Dry Flowable in Rabbits: Study Numbers 83-323-06 and 83-333-06. Unpublished study prepared by Mobay Chemical Corporation. 16 p.

149331	Mihail, F. (1980) MEB 6447: Acute Toxicity Studies: Report No. 9277. Unpublished study prepared by Bayer AG. 10 p.

149336	Unger, T.; Van Goethem, D.; Shellenberger, T. (1982) A Terato- logical Evaluation of Bayleton in Mated Female Rats: MRI Project No. 7272-B. Unpublished study prepared by Midwest Research Institute. 52 p.

      150484		Hoffmann, K.; Vogel, O. (1984) KWG 0519 (C.N. Triadimenol) First Chronic Study of Toxicity to Dogs on Oral Administration (Two- year Feeding Study): KWG 0519/005. Unpublished study prepared by Bayer AG. 254 p.

151246	Heimann, K.; Schilde, B. (1984) KWG 0519 (Suggested Common Name: Triadimenol, the Active Ingredient of BAYTAN): Subacute Dermal Toxicity Study on Rabbits: Bayer Report No.: 12496. Unpublished study prepared by Bayer AG. 66 p.

151247	Hoffmann, K. (1984) KWG 0519 (c.n. Triadimenol): Second Chronic Study of Toxicity to Dogs on Oral Administration (Six-month Feeding Study): Report No.: 12971. Unpublished study prepared by Bayer AG. 127 p.

151248	Loeser, E.; Eiben, R. (1984) KWG 0519 (Proposed c.n. Triadimenol): Generation Study on Rats: Report No.: 12390. Unpublished study prepared by Bayer AG. 250 p.

155075	Eiben, R. (1984) MEB 6447 (Triadimefon): Two-generation Study with Rats: Supplementary Study: Report No. 12712. Unpublished study prepared by Bayer AG, Institute of Toxicology. 168 p.

159012	Hoffmann, K. (1984) Investigation of the Body Weight Development of Beagle Dogs in Chronic Toxicity Studies (Survey, 1973-1983): Pharma Report No. 12385. Unpublished study prepared by Bayer Pharmaceuticals Div. 14 p.

159343	Herbold, B. (1985) MEB 6447 C.N. Triadimefon: Pol Test on E. coli To Evaluate for Potential DNA Damage: Revised Report: Report No. 12780. Unpublished translation, Mobay report no. 86793, of study prepared by Bayer AG. 16 p.

159558	Heimbach, F. (1985) Growth Inhibition of Green Algae (Scenedesmus subspicatus) by Triadimefon (Technical): Test Report: Report HBF/A112: Study No. A105/85. Unpublished study prepared by Bayer AG. 18 p.

231311	Chemagro Agricultural Division, Bayleton Fish and Wildlife Safety, June, 18 1977.

246736	Mobay Chemical Corporation, Corporate Toxicology Department, Stanley

Life Cycle Study of Triadimefon to Daphnia Magna; Research Center; Study Number 81--667-01 Author: D. W. Lang.

251243	Mobay Chemical Corporation, Toxicity of Triadimefon (Bayleton) To Rainbow Trout Early Life Stages; Report No. 85939 September 9, 1983.

254693	Mobay Chemical Corporation, Bayleton Fish and Wildlife Data, Brochure, confidential

document number AS 84-2461; September, 1984.

264276	Mobay Corporation Environmental Health Research;Toxicology of Bayleton;

Supplement No. 5 to Original Brochure Date June 6, 1977; Brochure No. 1441; February 21, 1986.

266051	Bayer AG, 1986, Influence of KWG 0519 on the Growth of Green Algae in Nutrient Solution, Report No. 82684

5001991	Stevenson, J. H.; The Acute Toxicity of Unformulated Pesticides to Worker Honey

Bees; Rothamsted Experimental Station Harpenden New Hampshire.

40283102	Mobay Corporation Coroporate Toxicology Department; Effect of

Triadimenol (Baytan) of Mallard Duck Reproduction; Report No. 86385; February 28, 1984;  Report Author: J.C. Carlisle.

40307804	Becker, H. (1987) Embryotoxicity (including Teratogenicity) Study with KWG 0519 in the Rat: Report No. 94463. Unpublished compil- ation prepared by Research and Consulting Co. AG. 494 p.

40307805	Becker, H.; Mueller, E.; Vogel, W.; et al. (1987) Embryotoxicity (including Teratoegenicity) Study with KWG 0519 in the Rabbit: Project 065248: Report No. 94762. Unpublished compilation pre- pared by Research and Consulting Co. AG. 318 p.

40477401	Talbott, T. (1987) Supplement 1: Product Chemistry of Bayleton Technical: Laboratory Project ID ANR-00587. Unpublished study prepared by Mobay Corporation. 55 p.

40615201	Pither, K. (1988) Triadimenol--Magnitude of Residues on Bananas: Baytan Objective No. 5781. Unpublished study prepared by PTRL. 86 p.

40752101	Bomhard, E. (1986) MEB 6447: Carcinogenicity Study on NMRI Mice (21-Month Administration in the Feed): Report No. 87287. Unpu- blished study prepared by Bayer AG. 1190 p.

40819101	Nagata, T. (1981) Triadimefon Subacute Toxicity on Rats: 3-Month Feeding Study: Report No. 69700. Unpublished study prepared by Shin Nippon Kagaku Co., Ltd. 229 p.

40865101	Bombard, E.; Hahnemann, S. (1986) MEB 6447: Common Name: Triadime- fon, the Active Ingredient of Bayleton: Carcinogenicity Study on NMRI Mice: Project ID 87287. Unpublished study prepared by Bayer Ag. 5 p.

40887702	Becker, H. (1987) Embryotoxicity (Including Teratogenicity) Study with KWG 0519 in the Rat: Project ID 94463. Unpublished study prepared by Research and Consulting Co. 13 p.

40887703	Becker, H. (1987) Embryotoxicity (Including Teratogenicity) Study with KWG 0519 in the Rabbit: Project ID 94762. Unpublished stu- dy prepared by Research and Consulting Co. AG. 9 p.

40969801	Foushee, G. (1988) Baytan, Multiresidue Method Trial: Project ID; 87-4705; Mobay Report No. 95672. Unpublished study prepared by Langston Laboratory, Inc. 526 p.

41051401	Pither, K. (1989) Triadimenol--Magnitude of Residues on Bananas: Baytan Objective No. 5781: Mobay Report No. 95684-1. Unpublished study prepared by PTRL. 11 p.

41242801	Rockwell, J. (1988) Residues of Baytan and Its Metabolites in Cotton: Morse Laboratories 45659, 45661. Unpublished study pre- pared by Morse Laboratories. 354 p.

41446201	Clemens, G.; Hartnagel, R. (1990) Teratology Study in the Rabbit with MEB 6447 (Triadimefon): Report No.: MTD0149. Unpublished study prepared by Miles, Inc. 155 p.

41498401	Clemens, G.; Troup, C.; Hartnagel, R. (1990) Developmental Toxicity Study in the Rat with Baytan Technical: Report No.: MTD0156. Unpublished study prepared by Miles, Inc., Toxicology Depart- ment. 263 p.

41554001	Sheets, L. (1990) Dermal Sensitization Study with Technical Grade Triadimefon (Bayleton) in Guinea Pigs: Lab Project Number: 90-324-EL. Unpublished study prepared by Mobay Corp. 21 p.

41616001	Talbot, T. (1990) Product Chemistry of Bayleton Technical: Supple- ment 1: Lab Project Number: 80298; 85997; 91321. Unpublished study prepared by Mobay Corp. 25 p.

41616002	Warren, D. (1990) Acute Four-Hour Inhalation Toxicity Study with Bayleton Technical in Rats: Lab Project Number: 90-042-GL. Un- published study prepared by Mobay Corp. 31 p.

41616004	Sheets, L. (1990) Primary Dermal Irritation Study with Technical Grade Triadimefon (Bayleton) in Rabbits: Lab Project Number: 90-325-EK. Unpublished study prepared by Mobay Corp. 16 p.

41616008	Daly, D. (1987) Soil Adsorption/Desorption with ?carbon 14|- Bayleton: Final Report: Lab Project Number: 36354. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 50 p.

41619901	Grau, R. (1990) Triadimefon: Bioconcentration in Fish: Lab Project Number: E2880381/0. Unpublished study prepared by Mobay Corp. 55 p.

41686101	Leimkuehler, W.; Lenz, C. (1989) The Anaerobic Soil Metabolism of ?Triazole-3,5 carbon 14| Triadimefon 1: Lab Project Number: BL0- 42102. Unpublished study prepared by Mobay Corp. 33 p.

41686102	Leimkuehler, W.; Lenz, C.; Stevenson, T. et al. (1989) The Aerobic Metabolism of ?Triazole-3,5, carbon 14| Triadimenfon1: Lab Pro- ject Number: BL042101. Unpublished study prepared by Mobay Corp. 42 p.

41686103	Carey, R. (1990) Subsurface Soil Investigation Report: Lab Project Number: ML022101. Unpublished study prepared by Mobay Corp. 44 p.

41686104	Carey, R. (1990) Subsurface Soil Investigation Report: Lab Project Number: ML022101. Unpublished study prepared by Mobay Corp. 72 p.

41782501	Sheets, L. (1990) Primary Eye Irritation Study with Bayleton 50% WP in Rabbits: Lab Project Number: 90-335-GY. Unpublished study prepared by Mobay Corporation 18 p.

41809401	Williams, B. (1991) Triadimefon: Magnitude of the Residue Crop Field Trials: Lab Project Number: 38613-1: BL19GR01: 100122. Unpublished study prepared by Analytical Bio-Chemistry Laborato- ries Inc. 323 p.

41895901	Stafford, T. (1991) Technical Bayleton: An Acute Oral LD50 with Bobwhite Quail (Colinus virginianus): Lab Project Number: BL711- 701: 101222. Unpublished study prepared by Mobay Corp. 21 p.

41922101	Cain, K.; Moore, K. (1991) Stability of Triadimefon in Sterile Aqueous Buffer Solutions: Lab Project Number: BL072401: 101291. Unpublished study prepared by Mobay Corp. 26 p.

41922102	Gagliano, G. (1991) Chronic Toxicity of Bayleton Technical to the Waterflea (Daphnia magna) Under Static Renewal Conditions: Lab Project Number: BL840701: 101298. Unpublished study prepared by Mobay Corp. 57 p.

41922103	Cohle, P.; Friesen, K. (1991) Early Life-Stage Toxicity of Bayleton to Fathead Minnows (Pimephal-es promelas) in a Flow-through Sys- tems: Lab Project Number: 39006: 101301. Unpublished study pre- pared by ABC Laboratories, Inc. 75 p.

41976601	Ver Hey, M. (1991) Bayleton, KWG 1323 and KWG 1342: Multiresidue Method Testing: Lab Project Number: MOBAY/1093: BL161601. Un- published study prepared by Colorado Analytical Research & Dev., Corp. 380 p.

41976602	Williams, B.; Conrath, B. (1991) Triadimefon/Triadimenol Freezer Storage Stability Study in Wheat Gain, Grapes, and Tomatoes: Amended Report: Lab Project Number: 36987-1: BL142301: 100105. Unpublished study prepared by Analytical Bio-Chemistry Labora- tories. 417 p.

42013201	Pither, K. (1991) Triademefon (500DF): Magnitude of the Residue on Pineapple Processed Products: Lab Project Number: BL19PN02B: 101325. Unpublished study prepared by ABC Labs, Inc. and Maui Pineapple Company, Ltd. 324 p.

42089601	Clemens, G.; Hartnagel, R. (1991) Teratology Study in the Rabbit with MEB 6447: Supplement to MRID 41446201: Lab Project Number: 100026: MTD0149. Unpublished study prepared by Miles, Inc., Tox. Dept. 11 p.

42112901	Krolski, M.; Bosnak, L. (1991) Addendum I: Additional Characteriza- tion of the Degradation Products Found in the Triadimefon Aqueous Photolysis Study: Lab Project Number: 101357: BL082402. Unpublished study prepared by Mobay Corp. 25 p.

42123401	Krolski, M. (1991) Addendum I: Raw Data on the Fate of ?carbon 14| Triadimefon on Tomatoes and Cucumbers: Lab Project Number: 68593 -1. Unpublished study prepared by Stoner Labs, Inc. 20 p.

42123402	Minor, R. (1991) Addendum I: Raw Data for the Metabolism of Triadim efon in Apples: Lab Project Number: 53621-1. Unpublished study prepared by Mobay Corp. 19 p.

42123403	Duah, F. (1991) Addendum I: Raw Data on The Metabolism of Bayleton on Grapes: Lab Project Number: 88790-1. Unpublished study pre- pared by Mobay Corp. 27 p.

42123404	Chopade, H. (1991) Addendum I: Raw Data for the Metabolism of Triad imefon in Male and Female Pigs: Lab Project Number: 66509-1. 51 p.

42153901	Bomhard, E.; Schilde, B. (1991) MEB 6447: Chronic Toxicity and Cancerogenicity Studies on Wistar Rats with Administration in Diet over a Period of 105 Weeks: Lab Project Number: 20774: 101922. Unpublished study prepared by Bayer Ag., Dept. of Toxicology. 1029 p.

42192701	Nishimura, N. (1983) Subacute Toxicity Study of KWG 0519 in Dietary Administration to Rats for 13 Weeks: Lab Project Num- ber: 101939. Unpublished study prepared by Bozo Research Cent- er Inc. 320 p.

42224104	Leikmuehler, W.; Lenz, C.; Stevenson, T.; et al. (1989) The Aerobic Metabolism of (Triazole-3,5-carbon 14) Triadimenfon (sic): Lab Project Number: BLO42101: 99773. Unpublished study prepared by Mobay Corp. 45 p.

42242701	Grace, T.; Cain, K. (1991) Dissipation of Triadimefon in California Soils: Revised: Lab Project Number: 100150: BL830089R0A: 892010.1-1K. Unpublished study prepared by Plant Science, Inc., Siemer and Associates, Inc., and Ricerca, Inc. 4388 p.

42307801	Fontaine, L. (1992) Supplemental Product Chemistry of Bayleton Technical: Lab Project Number: MCL0054. Unpublished study prepared by Miles, Inc. 22 p.

42307802	Fontaine, L. (1992) Supplemental Product Chemistry of Bayleton Technical: Lab Project Number: ANR-00692: ANR-00792. Unpublished study prepared by Miles, Inc. 20 p.

42307803	Fontaine, L. (1992) Supplemental Product Chemistry of Bayleton Technical: Lab Project Number: 52834: 68665: 85997. Unpublished study prepared by Miles, Inc. 41 p.

42307804	Hoxter, K.; Lynn, S. (1992) Technical Bayleton: An Acute Contact Toxicity Study with the Honey Bee (LD50): Lab Project Number: 149-168B: BL761401: 102633. Unpublished study prepared by Wildlife Intl., Inc. 18 p.

42341501	Sheets, L.; Phillips, S.; Lake, S. (1992) A Repeated Dose 21-Day Dermal Toxicity Study with Technical Grade Triadimefon (Bayleton) in Rats: Lab Project Number: 91-122-LE; 102680. Unpublished study prepared by Miles, Inc. 215 p.

42342301	Stafford, T. (1992) Technical Bayleton: A One Generation Reproduction Study with Bobwhite Quail: Lab Project Number: BL741701. Unpublished study prepared by Miles, Inc. 106 p.

42342303	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Apples: Lab Project Number: BL 19AP01: 39590: 102625. Unpublished study prepared by Miles, Inc. and ABC Laboratories. 386 p.

42342304	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Cantaloupe: Lab Project Number: BL 19CP01: 39585: 102628. Unpublished study prepared by Miles, Inc. and ABC Laboratories. 319 p.

42342305	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Cucumber: Lab Project Number: BL 19CU01: 39586: 102630. Unpublished study prepared by Miles, Inc. and ABC Laboratories. 409 p.

42342306	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Pears: Lab Project Number: BL 19PR01: 39592: 102626. Unpublished study prepared by Miles, Inc. and ABC Laboratories. 303 p.

42342307	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Pineapple: Lab Project Number: BL 19PN02: 39256: 102649. Unpublished study prepared by Miles, Inc., ABC Laboratories, and Dole Packaged Foods Co. 416 p.

42342308	Burger, R. (1992) Triadimefon (50DF)--Magnitude of the Residue on Summer Squash: Lab Project Number: BL 19SQ01: 39589: 102629. Unpublished study prepared by Miles, Inc. and ABC Laboratories. 420 p.

42346601	Burger, R. (1992) Triadimefon (50DF)-Magnitude of the Residue on Processed Apple Commodities: Lab Project Number: BL-19AP02: 39591: 102636. Unpublished study prepared by Miles Inc. and ABC Laboratories. 233 p.

42356601	Cain, K.; Green, D. (1992) Leaching of Aged Residues of Triadimefon: Lab Project Number: BL092101: 102631. Unpublished study prepared by Miles Inc. 33 p.

42365001	Clemens, G.; Grosso, D.; Anderson, E.; et al. (1992) A Developmental Toxicity Study in Rabbits with Baytan Technical: Lab Project Number: MTD0256: 102692. Unpublished study prepared by Miles, Inc. 159 p.

42401201	Schmidt, J.; Head, L. (1992) Anaerobic Aquatic Metabolism of ?carbon-14| Triadimefon: Lab Project Number: BLO42401: 103207: 392331. Unpublished study prepared by ABC Labs, Inc. 60 p.

42409101	Chopade, H. (1992) Disposition and Metabolism of ?Phenyl-UL-carbon 14| Triadimefon in Rats: Lab Project Number: BLO41801: 102640. Unpublished study prepared by Miles, Inc. 251 p.

42613301	Mattern, G.; Parker, G.; Wendt, S. (1992) Confined Accumulation of (Phenyl-UL-(carbon 14)) Triadimefon Residues in Rotational Crops: Lab Project Number: BL051601: 91.027: P309W: 103806. Unpublished study prepared by Miles Inc., Plant Sciences, Inc. and PTRL West, Inc. 152 p.

42696308	Williams, B. (1992) Triadimenol--Magnitude of the Residue on Barley, 2.6F ST: Amended Final Report: Lab Project Number: 38700-1: BT19BA01: 100351. Unpublished study prepared by ABC Laboratory. 410 p.

42696309	Williams, B. (1992) Triadimenol--Magnitude of the Residue on Oats, 2.6F ST: Amended Final Report: Lab Project Number: 388151: BT19OA01: 100352. Unpublished study prepared by ABC Laboratories, Inc. 368 p.

42712101	Williams, B. (1992) Triadimenol--Magnitude of the Residue on Wheat, 2.6F ST. Unpublished study prepared by ABC Laboratories, Inc. 432 p.

42798901	Krolski, M. (1993) Fate of Bayleton-(carbon 14) as a 25 Percent Wettable Powder on Tomatoes and Cucumbers. Mass Spectral Data on (carbon 14) Triadimefon Residues.

42853401	Chopade, H. (1993) Metabolism of (Phenyl-UL-(carbon 14)) Triadimefon in Wheat: Lab Project Number: BL041601: 105162. Unpublished study prepared by Miles Inc., Agricultural Div. 141 p.

42856801	Hall, L.; Hartz, A. (1993) The Metabolism of (carbon 14) Triadimefon in the Lactating Goat: Lab Project Number: BL041001: 105161. Unpublished study prepared by Miles Inc. 160 p.

42857401	Williams, B.; Chickering, C. (1993) Triadimefon and Metabolites--Freezer Storage Stability Study in Raw Agricultural Commodities and Processed Products: Lab Project Number: 396832: BL131601: 102641-1. Unpublished study prepared by ABC Labs, Inc. 150 p.

42864901	Duah, F.; Smasal, T. (1993) Metabolism of Triadimefon in Laying Hens: Lab Project Number: BL040501: 105183. Unpublished study prepared by Miles Inc. 129 p.

43125401	Eberhart, D.; Ellisor, G. (1993) Evaluation of Potential Exposure Resulting from Contact with Bayleton-Treated Turf: Lab Project Number: 92E043: 105137. Unpublished study prepared by Miles, Inc. 432 p.

43256201	Bowers, L. (1994) Acute Toxicity of Bayleton Technical to the Rainbow Trout (Oncorhynchus mykiss) Under Static Renewal Conditions: Lab Project Number: BL812201: 106573. Unpublished study prepared by Miles Inc. 27 p.

43284401	Burger, R. (1994) Triadimefon (50DF): Magnitude of the Residue in Processed Grape Commodities: Lab Project Number: 105043: BL19GR03: 40712. Unpublished study prepared by Miles Inc. in cooperation with ABC Laboratories, Inc. and The National Food Laboratory, Inc. 648 p.

43304301	Bowers, L.; Frank, J. (1994) Acute Toxicity of BAYLETON Technical to the Bluegill (Lepomis macrochirus) under Static-Renewal Conditions: Lab Project Number: BL810301: 106758. Unpublished study prepared by Miles Environmental Research Section. 27 p.

43418301	Hall, L.; Hartz, A. (1994) The Metabolism of (carbon 14) Triadimefon in the Lactating Goat: Addendum 1: Additional Data as Requested by the EPA: Lab Project Number: BL041001: 105161-1. Unpublished study prepared by Miles, Inc. 12 p.

43418302	Duah, F.; Myers, T. (1994) Metabolism of Triadimefon in Laying Hens: Addendum 1: Additional Data as Requested by EPA: Lab Project Number: BL040501: 105183-1. Unpublished study prepared by Miles, Inc. 17 p.

43418303	Duah, F.; Myers, T.; Freeseman, P. (1994) Extraction Efficiency of the Analytical Method for Triadimefon Residues in Meat, Milk, and Eggs: Lab Project Numbers: BL200201: 106449. Unpublished study prepared by Miles, Inc. 44 p.

43462401	Duah, F. (1994) Storage Stability of Triadimefon Residues in Animal Tissues, Milk, and Eggs: Lab Project Number: BL130201: 106638. Unpublished study prepared by Miles Inc. 37 p.

43495509	Beyrouty, P. (1992) An Acute Study of the Potential Effects of Orally Administered Triadimefon on Behavior in Rats: Lab Project Number: 97132. Unpublished study prepared by Bio- Research Lab. Ltd. 276 p.

43705401	Fomenko, J. (1995) Evaluation of KWG 1732 (a Tridimefon Metabolite) Through the FDA Multiresidue Methods: Lab Project Numbers: K2162301: 106963: A012.009. Unpublished study prepared by Huntingdon Analytical Services. 97 p.

43870101	Bajzik, M. (1995) Independent Laboratory Validation of the Analytical Residue Method for Triadimefon and Metabolites in Plant Matrices (Report No. 106549): Lab Project Number: A012.014: BL111601: 107141. Unpublished study prepared by Huntingdon Analytical Services. 121 p.

43936101	Dreist, M.; Popp, A. (1996) MEB 6447 (Common Name: Triadimefon): Acute Oral Neurotoxicity Screening Study in Wistar Rats: Lab Project Number: 24636: 1058215: 107154. Unpublished study prepared by Bayer AG. 468 p.

43948601	Murphy, J. (1996) Triadimefon (50DF)--Magnitude of the Residue on Processed Apple Commodities: Addendum 1: Additional Information Requested by EPA: Lab Project Number: BL19AP02: 102636-1: 39591. Unpublished study prepared by Bayer Corp. 8 p.

44038901	Lenz, C. (1996) Triadimefon and Metabolites--Freezer Storage Stability Study in Raw Agricultural Commodities and Processed Commodities: Addendum 2: Lab Project Number: BL131601: 102641-2: 39683. Unpublished study prepared by ABC Laboratories, Inc. 586 p.

44041001	Chopade, H. (1996) Metabolism of (Phenyl-UL-(carbon 14)) Triadimefon in Wheat: Addendum 1--Storage Stability of (carbon 14) KWG 1732 in Wheat Grain: Lab Project Number: BL221601: 105162-1. Unpublished study prepared by Bayer Corp. 30 p.

44041002	Chopade, H. (1996) Extraction Efficiency of the Analytical Residue Method for the Determination of Triadimefon and Metabolite Residues in Plant Matrices: Determination of Aged (carbon 14) Triadimefon Residues in Wheat Grain: Lab Project Number: BL221601: 107343. Unpublished study prepared by Bayer Corp. 35 p.

44153501	Dreist, M.; Popp, A. (1996) MEB 6447 (Common Name: Triadimefon): Subchronic Neurotoxicity Screening Study in Wistar Rats: (Thirteen-Week Administration in the Diet with a Four-Week Recovery Period in Males and a Ten-Week Recovery Period in Females): Lab Project Number: 25315: T 6058265: 107477. Unpublished study prepared by Bayer AG. 786 p.

44166001	Fontaine, L. (1996) Product Chemistry of Bayleton Technical: Lab Project Number: 107296: 107241: 99642. Unpublished study prepared by Bayer Corp. 173 p.

44519801

	Shen, S. (1998) Determination of Residues of Baytan 30 in Processed Field Corn Fractions: Lab Project Number: 96-003: 963HI: 43514. Unpublished study prepared by ABC Labs., Inc. and Gustafson Research and Development Center. 458 p. {OPPTS 860.1520}

44519802	Shen, S. (1998) Determination of Residues of Baytan 30 in Processed Cotton Fractions: Lab Project Number: 96-001: 963HG: 43516. Unpublished study prepared by ABC Labs., Inc. and Gustafson Research and Development Center. 452 p. {OPPTS 860.1520}

44519803	Shen, S. (1998) Determination of Residues of Baytan 30 in Processed Wheat Fractions: Lab Project Number: 96-002: 963HH: 43513. Unpublished study prepared by ABC Labs., Inc. and Gustafson Research and Development Center. 462 p. {OPPTS 860.1520}

44740901	Schaldt, L. (1998) KWG 0519 Oncogenicity Study in CD-1 Mice (Dietary Administration over 18 Months): Lab Project Number: 28299: T4060738: 108689. Unpublished study prepared by Bayer AG. 1854 p.

45654503	Findlay, M.; Chester, G. (1995) Seed Treated Products: Worker Exposure During Sowing of Treated Seed with "Baytan": Lab Project Number: N(DEGREES)WER002. Unpublished study prepared by ZENECA Agrochemicals. 107 p.

46576207	Mithcell, H. (2005) Product Chemistry of Bayleton FLO Fungicide. Project Number: BR/2392, ANR/06605, 3414519/1. Unpublished study prepared by Bayer Corp. 134 p.

46578707	Mitchell, H. (2005) Product Chemistry of Tartan Flo Fungicide. Project Number: BR/2390, ANR/04605, ANR/04705. Unpublished study prepared by Bayer Corp. 205 p.

46836301	Mitchell, H. (2006) Product Chemistry of Bayleton 3.62% SC Systemic Fungicide. Project Number: BR/2462, 201435, ANR/03006. Unpublished study prepared by Bayer Corp. 180 p.

92188018	Eigenberg, D. (1990) Mobay Corporation Phase 3 Summary of MRID 00149336. A Teratological Evaluation of Bayleton (Triadimefon) in Mated Female Rats: Project 7272-B (Mobay Report 82270). Prepared by MIDWEST RESEARCH INSTITUTE. 22 p.

92188019	Eigenberg, D. (1990) Mobay Corporation Phase 3 Summary of MRID 00155075 and Related MRIDs 00032541. MEB 6447 (Triadimefon) Multigeneration Reproduction Study on Rats; (Triadimefon) Two-generation Study with Rats (Bayleton): Projects 8297 and 12712 (Mobay Reports 67752 and 82270). Prepared by BAYER AG. 38 p.

92188020	Loser, E. (1990) Mobay Corporation Phase 3 Reformat of MRID 00032541 and Related MRIDs 00155075. MEB 6447 (Triadimefon) Multigeneration Reproduction Study on Rats: Project Number 67752; Report No. 8297. Prepared by BAYER AG. 173 p.

92188025	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00025540. The Metabolism of BAYLETON in Apples: Project Report No. 53621. Prepared by MOBAY CORPORATION. 14 p.

92188026	Mango, R.; Puhl, R.; Thornton, J. (1990) Mobay Corporation Phase 3 Reformat of MRID 00025540. The Metabolism of BAYLETON in Apples: Project No. 53621. Prepared by MOBAY CORPORATION. 26 p.

92188027	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00031440 and Related MRIDs 00031441. Fate of BAYLETON-Carbon-14 as a 25% Wettable Powder on Tomatoes and Cucumbers: Project Report Nos. 68593 and 68594. Prepared by MOBAY CORPORATION. 13 p.

92188028	Nye, D. (1990) Mobay Corporation Phase 3 Reformat of MRID 00031440. Fate of BAYLETON-Carbon-14 as a 25 Percent Wettable Powder on Tomatoes and Cucumbers: Project Report 68593. Prepared by STONER LABORATORIES, INC. 33 p.

92188029	Puhl, R. (1990) Mobay Corporation Phase 3 Reformat of MRID 00031441. Further Identification of Polar Activity from BAYLETON Cucumber and Tomato Metabolism Samples: Project Report No. 68594. Prepared by MOBAY CORPORATION. 10 p.

92188030	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00098115. Metabolism of BAYLETON in Wheat: Project Report No. 80293. Prepared by MOBAY CORPORATION. 14 p.

92188031	Morgan, J.; Lenz, M. (1990) Mobay Corporation Phase 3 Reformat of MRID 00098115. Metabolism of BAYLETON in Wheat: Project Report No. 80293. Prepared by MOBAY CORPORATION. 29 p.

92188032	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00150893. Metabolism of BAYLETON on Grapes: Project Report No. 88790. Prepared by MOBAY CORPORATION. 12 p.

92188033	Fredrickson, R. (1990) Mobay Corporation Phase 3 Reformat of MRID 00150893. Metabolism of BAYLETON on Grapes: Project Report No. 88790. Prepared by MOBAY CORPORATION. 21 p.

92188034	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00025543. Metabolism of BAYLETON in the Cow: Project Report No. 66202. Prepared by MOBAY CORPORATION. 11 p.

92188035	Fredrickson, D. (1990) Mobay Corporation Phase 3 Reformat of MRID 00025543. Metabolism of BAYLETON in the Cow: Project Report No. 66202. Prepared by MOBAY CORPORATION. 19 p.

92188036	Premkumar, N. (1990) Mobay Corporation Phase 3 Summary of MRID 00033058. Metabolism of BAYLETON in Male and Female Pigs: Project No. 66509. Prepared by MOBAY CORPORATION. 16 p.

92188037	Pither, K. (1990) Mobay Corporation Phase 3 Reformat of MRID 00033058. Metabolism of BAYLETON in Male and Female Pigs: Project Report No. 66509. Prepared by MOBAY CORPORATION. 25 p.

92188038	Mathew, A. (1990) Mobay Corporation Phase 3 Summary of MRID 00033070. The Fate of BAYLETON-Carbon-14 in Poultry: Project Report No. 67482. Prepared by MOBAY CORPORATION. 16 p.

92188039	Nye, D. (1990) Mobay Corporation Phase 3 Reformat of MRID 00033070. The Fate of BAYLETON-Carbon-14 in Poultry: Project Report No. 67482. Prepared by STONER LABORATORIES, INC. 67 p.

92188040	Obrist, J.; Nichols, S.; Leimkuehler, W. (1990) Mobay Corporation Phase 3 Reformat of MRID 00025546. An Interference Study for the BAYLETON and KWG 0519 Residue Method for Crops: Project Report No. 68006. Prepared by MOBAY CORPORATION. 208 p.

92188041	Leimkuehler, W. (1990) Mobay Corporation Phase 3 Reformat of MRID 00125782. An Interference Study for BAYLETON Residue Method for Crops - Resolution of Interference for KWG 1342 and KWG 1323: Project Report No. 80567. Prepared by MOBAY CORPORATION. 225 p.

92188042	Chopade, H. (1990) Mobay Corporation Phase 3 Summary of MRID 00149163 and Related MRIDs 00025546, 00125782. Residue Analysis Procedure for BAYLETON and Metabolites in Plants: Project Report Nos. 80488, 68006 and 80567. Prepared by MOBAY CORPORATION. 16 p.

92188043	Obrist, J.; Leimkuehler, W. (1990) Mobay Corporation Phase 3 Reformat of MRID 00149163. Residue Analysis Procedure for BAYLETON and Metabolites in Barley and Wheat: Project Report No. 80488. Prepared by MOBAY CORPORATION. 28 p.

92188044	Minor, R. (1990) Mobay Corporation Phase 3 Summary of MRID 00090019 and Related MRIDs 00090020, 00063837, 00072538, 00149342, 00063835. Analytical Methods for BAYLETON in Various Animal Tissues: Project Report Nos. 69531, 80265, 68705, 68798, 69028 and 68887. Prepared by ANALYTICAL DEVELOPMENT CORP. 21 p.

92188045	Kruplak, J. (1990) Mobay Corporation Phase 3 Reformat of MRID 00090019. BAYLETON Total Residue Method Verification (Bovine): Project Report No. 69531. Prepared by ANALYTICAL DEVELOPMENT CORP. 158 p.

92188046	Obrist, J.; Nichols, S. (1990) Mobay Corporation Phase 3 Reformat of MRID 00063835. An Interference Study for the BAYLETON and KWG 0519 Residue Method for Bovine Tissues and Milk: Project report No. 68887. Prepared by MOBAY CORPORATION. 67 p.

92188047	Kruplak, J.; Weissenburger, B.; Bache (1990) Mobay Corporation Phase 3 Reformat of MRID 00063837. Determination of BAYLETON and KWG 0519 in Cattle Tissues: Project Report No. 68705. Prepared by ANALYTICAL DEVELOPMENT CORP. 31 p.

92188048	Kruplak, J.; Bache, B.; Breault, G. (1990) Mobay Corporation Phase 3 Reformat of MRID 00072538. Residue Analysis Procedure for the Determination of BAYLETON and KWG 0519 in Bovine Milk: Project Report No. 68798. Prepared by ANALYTICAL DEVELOPMENT CORP. 19 p.

92188051	Premkumar, N. (1990) Mobay Corporation Phase 3 Summary of MRID 00025541 and Related MRIDs 00098117, 41027902. Storage Stability of BAYLETON, BAYTAN, KWG 1323 and KWG 1342 in Apple Peel, Potatoes, Grapes and Wheat Green Forage; and Storage Stability of KWG 1323 and KWG 1342 in Wheat Grain: Project Report Nos. 54192, 80338 and 98432. Prepared by MOBAY CORPORATION. 11 p.

92188052	Thornton, J. (1990) Mobay Corporation Phase 3 Reformat of MRID 00025541. The Stability of BAYLETON and KWG 0519 Residues in Apple Peel During Frozen Storage: Project Report No. 54192. Prepared by MOBAY CORPORATION. 8 p.

92188053	Fredrickson, D. (1990) Mobay Corporation Phase 3 Reformat of MRID 00098117. The Stability of BAYLETON and BAYTAN Residues in Wheat Forage During Storage: Project Report No. 80338. Prepared by MOBAY CORPORATION. 7 p.

92188054	Bornatsch, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00090021. Effect of Feeding BAYLETON and the Metabolite KWG 0519 (BAYTAN) to Dairy Cattle -- Total Residue: Project Report No. 69930. Prepared by MOBAY CORPORATION. 9 p.

92188055	Kruplak, J. (1990) Mobay Corporation Phase 3 Reformat of MRID 00090021. Effect of Feeding BAYLETON and the Metabolite KWG 0519 (BAYTAN) to Dairy Cattle -- Total Residues: Project Report No. 69930. Prepared by ANALYTICAL DEVELOPMENT CORP. 247 p.

92188056	Mathew, A. (1990) Mobay Corporation Phase 3 Summary of MRID 00090022. Effect of Feeding BAYLETON and the Metabolite KWG 0519 (BAYTAN) to Poultry - Total Residue: Project No. 80281. Prepared by MOBAY CORPORATION. 12 p.

92188057	Kruplak, J.; Weissenburger, B. (1990) Mobay Corporation Phase 3 Reformat of MRID 00090022. Effect of Feeding BAYLETON and the Metabolite KWG 0519 (BAYTAN) to Poultry - Total Residues: Project Report No. 80281. Prepared by ANALYTICAL DEVELOPMENT CORP. 174 p.

92188060	Leslie, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00067381 and Related MRIDs 00109463. Triadimefon (BAYLETON 25WP Formulation) - Magnitude of the Residues on Chick Peas: Project Report Nos. 68905, 68906, 68907, 68908, 68909, 80723, 80930 and 80931; Mobay Report No. 100117-1. Prepared by MOBAY CORPORATION. 13 p.

92188061	Biehn, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00143953 and Related MRIDs 00153279. Triadimefon: Magnitude of the Residue on Raspberries: IR-4 No. 2552. Prepared by ICI Americas Inc. 20 p.

92188062	Leslie, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00072532 and Related MRIDs 00149342. Triadimefon (BAYLETON 50WP Formulation) - Magnitude of the Residues on Seed Grass: Project Report Nos. 80670, 80673, 80674, 80675 and 80676; Mobay Report No. 100114-1. Prepared by MOBAY CORPORATION. 12 p.

92188063	Leslie, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00128337. Triadimefon (BAYLETON 50WP Formulation) Magnitude of the Residues on Sugar Beets: Project Report Nos. 81198, 81199, 82800, 82801, 82802, 82803, 82804, 82805, 82806, 82807, 82808, 82809, 82811, 82814, 82815, 82816, 82817 and 82818; Mobay Report 100115-1. Prepared by MOBAY CORPORATION. 17 p.

92188064	Leslie, W. (1990) Mobay Corporation Phase 3 Summary of MRID 00098114 and Related MRIDs 00149329, 00061736. Magnitude of the Residues on Wheat: Objective No. (3012): Report Nos. 80494, 80495, 80530, 80542, 80545, 80546, 80547, 80550, 80551, 80552, 80553, 82821, 82874, 84208, 82822 and 82824; Mobay Report No. 100111-1. Prepared by MOBAY CORPORATION. 14 p.