UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES

MEMORANDUM

DATE:  	March 23, 2006

SUBJECT:	Dicloran (DCNA) Revised Acute and Chronic Dietary Exposure Assessments for the Reregistration Eligibility Decision (Phase 3)

PC Code:	031301

DP Barcode:	D294456

REVIEWER:	Christine L. Olinger, Chemist

Reregistration Branch 1

Health Effects Division (7509C)

THROUGH:	Sheila Piper, Chemist

William Cutchin, Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509C)

and

Whang Phang, Ph.D., Branch Senior Scientist

Reregistration Branch 1

Health Effects Division (7509C)

TO:		Toiya Goodlow, Risk Assessor

Reregistration Branch 1

Health Effects Division (7509C)

And

James Parker, Chemical Review Manager

Special Review and Reregisration Division (7508C)

Executive Summary

Acute and chronic dietary risk assessments were conducted using the Dietary Exposure Evaluation Model - Food Commodity Intake Database (DEEM-FCID(, Version 2.03) which uses food consumption data from the USDA(s Continuing Surveys of Food Intakes by Individuals (CSFII) from 1994-1996 and 1998.  The analyses were performed to support the reregistration eligibility decision (Phase 3).  The estimated drinking water concentrations and safety factors have been changed since the assessment conducted in Phase 1.

Acute Dietary Exposure Results and Characterization

A refined acute dietary exposure assessment was required as the exposures for females 13-49 years old exceeded HED(s level of concern assuming 100% crop treated and tolerance values.  No acute endpoints were identified for the general U.S. population.  USDA Pesticide Data Program (PDP) monitoring data were used for all commodities except rhubarb, assuming non-detectable residues were at the limit of detection (LOD).  The analysis was conducted for food alone and using estimated drinking water concentrations (EDWCs) from modeled values for either surface or ground water sources.  At the 99.9th percentile of exposure, the estimated exposure was at 9.9-10% of the acute Population Adjusted Dose (aPAD) for females 13-49 years old.

Chronic Dietary Exposure Results and Characterization

A refined chronic dietary exposure assessment was required as the exposures for all populations exceeded HED(s level of concern assuming 100% crop treated and tolerance values.  USDA Pesticide Data Program (PDP) monitoring data were used for all commodities except rhubarb, assuming non-detectable residues were at the limit of detection (LOD).  No adjustments for percent crop treated were made.  Using this refinement, the exposure for combined food and water were below 10% of the chronic population adjusted dose (cPAD) for most population sub-groups.  The most highly exposed subgroup was children (ages 1-2 years old), with exposures at 13% of the cPAD for food alone and 14-15% of the cPAD for food and water combined.

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects).  This dose is referred to as the population adjusted dose (PAD).  The PAD is equivalent to the Reference Dose (RfD) divided by the special FQPA Safety Factor.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site:  (Available Information on Assessing Exposure from Pesticides, A User(s Guide,( 6/21/2000, web link:  http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf ; or see SOP 99.6 (8/20/99).

II.	Residue Information

Dicloran (2,6-dichloro-4-nitroaniline), also known as dichloronitroaniline (DCNA), is a fungicide registered on various food/feed crops to control pathogenic species such as Botrytis, Monilinia, Rhizopus, Sclerotinia, and Sclerotium.  Dicloran is currently registered for preharvest uses on apricots, beans (snap), celery, cherries (sweet), cucumbers, endive (escarole), fennel, garlic, grapes, lettuce (head and leaf), nectarines, onions, peaches, plums (fresh prunes), potatoes, rhubarb, shallots, and tomatoes.  It is also registered for postharvest uses on carrots and sweet potatoes.  A petition, PP#7F04879, is pending for the establishment of permanent tolerances resulting from proposed uses on peanuts (preharvest), carrots (preharvest), and tomatoes (postharvest).  There are also pending pre-harvest uses on fennel, shallot, and the leafy greens subgroup (Subgroup 4a).

The nature of the residue in plants is adequately understood based on acceptable metabolism studies with dicloran on peaches, potatoes, and lettuce.  The plant metabolism studies were presented to the HED Metabolism Assessment Review Committee (MARC) on May 8, 2001 (T. Bloem,  D274726, 5/8/2001), who concluded that only the parent compound should be included in the tolerance expression for primary crops.  The Committee also recommended that one major metabolite, 2,6-dichloro-4-hydroxyaniline (DCHA), should be included in the risk assessments for all presently registered crops (excluding potato).  The residues of concern in potatoes, for the purpose of risk assessment, are dicloran, DCHA, and a group of metabolites designated as Unknown 1 which comprised approximately half of the residues characterized in the potato study.  The registrant tentatively concluded that Unknown 1 was most likely composed of glutathione-conjugated dicloran metabolites which had been deaminated, dechlorinated, and/or hydroxylated, and/or in which the nitro group had been reduced and acetylated.

No magnitude of residue data are available for DCHA or the Unknown metabolite 1.  Adjustment factors have been developed based on the metabolism studies to account for potential exposure to these metabolites of concern.  A summary of these factors is presented in Table 1 along with the metabolism data on which they are based and the crops to which they will be applied.  No factors will be applied to the post-harvest uses, as there is minimal opportunity for degradation of these uses to the metabolite.

Table 1.  Summary of Adjustment Factors to Account for DCNA Metabolites

Study

Peaches

14-day PHI

Potato Tubers

14-day PHI

Potato Vines

14-day PHI

Lettuce

20-day PHI

Dicloran

32%TRR

10

39

74%

DCHA

11%TRR

15

<1

<1

Unknown 1

<1

50%

30

<1

Factor used to approximate total ROC 1 for Risk Assessment

multiply dicloran per se residues by 1.3

multiply dicloran per se residues by 7.5

multiply dicloran per se residues by 1.8

No adjustment needed

Applies to:

grapes (1-day PHI)

garlic, onion, potato, shallot

Snap beans,

Cucumber, tomato

Pre-harvest treatments: celery, endive, fennel, lettuce, rhubarb, radicchio.  Post-harvest treatments: carrot, sweet potato, stone fruit

1 ROC = Residue of Concern

Tolerances are established under 40 CFR (180.200 for residues of dicloran per se in/on various raw agricultural commodities.  No tolerances have been established for animal commodities.

The MARC was unable to make a decision on the water degradates of concern, as the environmental fate data are limited.  However, a new aerobic aquatic metabolism study was submitted which identified an additional dicloran degradate: 2,6-dichlorobenzoic acid (DCBA).  DCBA was found at maximum concentrations of 9.2-9.3% of the applied radiolabeled material in the water phase (7 days) and 3.3-5.8% of the applied material in the sediment phase (14 days).   By study termination DCBA had decreased to 1.0-1.7% of applied dicloran in the water phase.  There were no major degradates of DCNA detected in the previously reviewed laboratory fate studies (i.e. none accounted for as much as 10% of radioactivity measured at any point in the studies), with the exception of the transformed chemical present as nonextractable residues. The minor degradates of DCNA expected in the environment are:  2,6-dichloro-p-phenylenediamine (DCPD); 4-amino-3,5-dichloroacetanilide (DCAA); and 2,6-dichloro-4-hydroxyaniline (DCHA); and 3,5-dichloro-4-hydroxyacetanilide (3,5HA).  There are no data on the fate and mobility of these compounds.  For these reasons, the Tier 1 Drinking Water Assessment for DCNA included only the parent compound (C. Sutton, D294452, 1/24/2006).  The EDWC for ground water is 1.3 ppb for any duration; the EDWCs from surface water for acute and chronic assessments are 172.8 ppb and 1.8 ppb, respectively.

Residue Data used for Acute and Chronic Assessments:

A summary of the residue values used in this assessment are presented in Table 2.  Pending uses on fennel, shallot, and the leafy greens subgroup (Subgroup 4a) are included in this assessment as there are sufficient residue data to support establishment of tolerances for these commodities.  Current or reassessed tolerance values were used for the acute assessment; no further refinement was needed as the exposures were below the level of concern.

Refinements were required for the acute and chronic analyses.  USDA Pesticide Data Program (PDP) monitoring data were used for all commodities with the exception of rhubarb.  If there were detectable residues, residue data distributions for acute probabilistic analyses were created from the PDP data.  The limit of detection was used to represent samples with non-detectable residues.  If all of the residues were non-detectable then the limit of detection was used directly.  The residue data files used are attached at the end of this document.

An average residue value was estimated for the chronic analyses using the formula below.  The average limit of detection was used to represent the residues with non-detectable residues.

ARchronic = [(Ndetects x Avg.detects) + (Nnon-detects x Avg.non-detects)]/Ntotal, where

Ndetects = Number of samples with detectable residues;

Avg.detects = Average of detectable residues;

Nnon-detects = Number of samples with non-detectable residues;

Avg.non-detects = Average of limits of detection for all samples with non-detectable residues;

Ntotal = Total number of samples.

Reliable percent crop treated data were not available for the post-harvest uses, which lead to the highest residues, so no zeroes were used to represent those samples that were not treated.

Processing Factors

Adequate processing data for DCNA per se are available for grapes, plums, and tomatoes.  No concentration of DCNA per se residues in raisins, so a processing factor of 1 was applied to raisins.  The dried prune factor of 1.9 was applied to dried prunes, dried apricots, and dried peaches.  A processing factor of 1.3 was applied to the tier 1 analyses; PDP monitoring data are available for grape juice, so no processing factor was needed.  Processing factors of 2.0 and 1.2 were applied to tomato paste and tomato puree, respectively.  Default processing factors from DEEM( 7.81 were applied to cherry juice, dried onions, plum juice, dried potatoes, and dried tomatoes.

Table 2.  Data and Residue Estimates Used in Dietary Analyses 1

RAC	Food

Forms	Data Source - Chronic ARs2	Years for PDP Data	No. of Samples	No. of Detectable Residues	Averages from PDP, ppm	Anticipated Residue Estimates, ppm

Detects	LOD	Acute 3	Chronic 4

Apricot	All except canned and babyfood	PDP – Peaches -Fresh only 1993-1997, 2000-2002	3626	767	0.709	0.004	PDP – Peaches	0.153

	Canned and babyfood	PDP- Peaches - Canned	2003-2004	1485	0	None	0.009 0.009	0.009

Bean, Snap	All except Canned	PDP	1993-1995, 2000, 2001, 2004	3687	93 0.478	0.0077	RDF – Beans	0.02

Beans, Snap, Canned	All	PDP	1997, 1998, 2003, 2004	1992	2	0.013	0.0062 RDF – Canned Beans	0.0062

Carrot	All	PDP	1994-1996, 2000-2002	3365	12	0.162	0.0066	RDF - Carrots 0.0071

Celery	All	PDP	1993, 2000 – 2002	1781	939	0.346	0.0077	RDF – Celery 0.19

Cherry, Sweet	All	PDP	2000, 2001	561	0	None	0.008	0.008	0.008

Cucumber	All	PDP	1999, 2000, 2002, 2003, 2004	2946	10	0.0094	0.0067	RDF – Cucumbers	0.0068

Endive	All	PDP - Lettuce	1999-2001	1479	3	0.0247	0.0094	RDF – Lettuce 0.0094

Fennel	All	PDP - Celery	1993, 2000 – 2002	1781	939	0.346	0.0077	RDF – Celery	0.19

Garlic	All	PDP - Onions	2002-2003	1482	2	0.011	0.0074	RDF – Onions 0.0074

Grape	All except Juice	PDP	1993-1996, 2000, 2001, 2004	4100	152	0.135 0.0067	RDF – Grapes	0.011

	Juice	PDP	1998, 1999	1379	0	None	0.0094	0.0094	0.0094

Lettuce	All	PDP	1999-2001	1479	3	0.0247	0.0094	RDF – Lettuce	0.0094

Nectarine	All	PDP	2000	704	175	0.106	0.0039	RDF – Nectarines	0.029

Onion	All	PDP	2002-2003	1482	2	0.011	0.0074	RDF – Onions	0.0074

Peach	All except canned and babyfood	PDP - Fresh only	1993-1997, 2000-2002	3626	767	0.709	0.004	PDP – Peaches	0.153

	Canned and babyfood	PDP- Canned	2003-2004	1485	0	None	0.009	0.009	0.009

Plum	All except canned and babyfood	PDP – Peaches -Fresh only 1993-1997, 2000-2002	3626	767	0.709	0.004	PDP – Peaches	0.153

	Canned and babyfood	PDP- Peaches - Canned	2003-2004	1485	0	None	0.009 0.009	0.009

Potato	All	PDP	1994, 1995, 2000-2002	2873	22	0.052	0.0083	RDF – Potatoes	0.0087

Radicchio	All	PDP - Lettuce	1999-2001	1479	3	0.0247	0.0094	RDF – Lettuce	0.0094

Rhubarb	All	Tol.	NA	NA	NA	NA	NA	Tol. - 10	Tol. - 10

Shallot	All	PDP - Onions	2002-2003	1482	2	0.011	0.0074	RDF – Onions 0.0074

Sweet Potato	All	PDP	1996-1998, 2003, 2004	3000	1586	0.372	0.0065	RDF – Sweet Potatoes	0.20

Tomato	All except Paste and Puree	PDP	1997-1999, 2003-2004	3448	66 0.0691	0.0082	RDF – Tomatoes	0.0094

	Paste	PDP	2000	369	0	None	0.006	0.006	0.006

	Puree	PDP	1999-2000	737	0	None	0.007	0.007	0.007

1.	Percent crop treated data were not used in anticipated residue (AR) estimation.

2.	PDP = USDA Pesticide Data Program

3.	Residue data files (RDF) may be found as an attachment to this document.

4.	Chronic Anticipated Residue = [(no. of detects x average of detects) + (no. of non-detects x average LOD)]/total no. of samples

III  DEEM-FCID( Program and Consumption Information

Several reasonable peer-reviewed software programs have recently been emerging for modeling dietary exposure to pesticides.  For a variety of technical, historical, and availability reasons, DEEMTM was the program generally used by EPA(s Office of Pesticide Programs for conducting its dietary risk assessments.  With the advent and current availability of a number of other exposure software programs, OPP, registrants, and other interested parties have available to them the option of selecting other peer-reviewed exposure software in conducting risk assessments for pesticides.  Dietary Exposure assessments may also be performed with other, similar programs, and if submitted, such results will be reviewed by EPA for acceptability and comparability to existing peer-reviewed software being used by OPP.

DCNA acute and chronic dietary exposure assessments were conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database (DEEM-FCID(, Version 2.03), which incorporates consumption data from USDA(s Continuing Surveys of Food Intakes by Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98 data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods (as consumed( (e.g., apple pie) are linked to EPA-defined food commodities (e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups, but for acute exposure assessment are retained as individual consumption events.  Based on analysis of the 1994-96, 98 CSFII consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue intake estimate.  The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD.  This procedure is performed for each population subgroup.

For acute exposure assessments, individual one-day food consumption data are used on an individual-by-individual basis.  The reported consumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or (matched( in multiple random pairings with residue values and then summed in a probabilistic assessment.  The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis.  In accordance with HED policy, per capita exposure and risk are reported for all tiers of analysis.  However, for tiers 1 and 2, any significant differences in user vs. per capita exposure and risk are specifically identified and noted in the risk assessment.

IV.	Toxicological Information

The hazard characterization for DCNA RED has been prepared by B. Chin (personal communication, 2/13/06) to be incorporated into the human health risk assessment (T. Goodlow, in review).  The toxicological database on DCNA is adequate for toxicity endpoint selection.  The target organs include the liver, kidney, spleen and hematopoietic system (anemia) particularly destruction of red blood cells.  It is positive in the Ames test both in the presence and the absence of S9 activation and negative in both the in vitro chromosome aberration assay in human lymphocytes and primary rat hepatocyte unscheduled DNA synthesis assay.  It does not appear to be a reproductive toxicant.  The developmental toxicity study in rats showed increased incidences of supernumerary rudimentary ribs and also decreased fetal weights in the presence of maternally toxic dose.  Chronic toxicity study in rats showed that dicloran caused changes in clinical chemistry, increased liver weights, hepatocyte hypertrophy, vacuolar alterations of the brain and spinal cord, prostate atrophy, degeneration of the seminiferous tubules, and hypospermia in the epididymides at higher doses than those selected for risk assessment.  The committee members of CARC evaluated the carcinogenicity studies in rats and mice and related toxicity data on dicloran and concluded that no quantification of cancer risk is required based on the (Suggestive Evidence of Carcinogenic Potential( classification.

Based on the recommendation for requiring a developmental neurotoxicity study a database uncertainty factor (10x) has been applied to the acute and chronic dietary risk assessments.  The dicloran risk assessment team evaluated the quality of the hazard and exposure data and recommended that based on the hazard and exposure data, the special FQPA SF be reduced to 1X.  A summary of the doses and endpoints selected for the dietary risk assessments is presented in Table 3.

Exposure

Scenario	Dose Used in Risk Assessment, UF 	Special FQPA SF* and Level of Concern for Risk Assessment	Study and Toxicological Effects

Acute Dietary

(females 13-49)	NOAEL = 50 mg/kg/day

UF = 1000

Acute RfD = 0.05 mg/kg/day

	FQPA SF = 1X

aPAD = acute RfD (0.05)

              FQPA SF (1)

= 0.05 mg/kg/day	Developmental toxicity study in rats

LOAEL = 100 mg/kg/day based on increased incidences of supernumerary rudimentary ribs and also decreased fetal weights.

Acute Dietary

(general population including infants and children) 	NOT APPLICABLE.  A dose and endpoint were not selected for this population group because there were no effects observed in oral toxicology studies including maternal toxicity in the developmental toxicity studies in rats and rabbits that are attributable to a single exposure (dose).

Chronic Dietary

(All populations)	NOAEL= 2.5 mg/kg/day

UF = 1000

Chronic RfD =

0.0025 mg/kg/day	FQPA SF = 1X

cPAD = chronic RfD

             FQPA SF (1)

= 0.0025 mg/kg/day	One Year Chronic Toxicity Study in Dogs

LOAEL = 25 mg/kg/day based on

clinical chemistry (increased alkaline phosphatase in both sexes and increased cholesterol in males),

increased liver weights, hepatocyte hypertrophy, vacuolar alterations of the brain and spinal cord, prostate atrophy, degeneration of the seminiferous tubules, and hypospermia in the epididymides

Cancer (oral, dermal, inhalation)	 “Suggestive Evidence of Carcinogenic Potential”

V.	Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD.  The DEEM-FCID( analyses estimate the dietary exposure of the U.S. population and various population subgroups.  The results of the acute and chronic dietary assessments reported in Tables 4, 5, and 6 are for the general U.S. Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50+ years.  Table 4 includes the results for food alone, Table 5, food and surface water, and Table 6, food and ground water.

Results of Acute Dietary Exposure Analysis

The only acute dietary assessment conducted was for females 13-49 years old, as no endpoint was identified for the general population or any other subgroups.  Analyses were conducted for food alone, and including either surface water sources or groundwater sources as the drinking water source, assuming that residues were at current and/or reassessed tolerance level and the percent crop treated was 100%.  At the 95% of exposure the percent of aPAD was 260%.  Refined analyses were conducted using the distribution of residue data from the USDA PDP monitoring program for all commodities except rhubarb.  Reliable percent crop treated data are not available for crops receiving post-harvest treatments of DCNA, so all samples with non-detectable residues were assumed to have residues at the limit of detection (LOD), and no samples were assumed to have zero residues.  The refined exposure from food alone was at 9.9% of the aPAD, and from food plus drinking water, 10% of the aPAD.

Results of Chronic Dietary Exposure Analysis

Chronic dietary exposure analyses were conducted including both food and water using drinking water estimates from both surface and ground water sources.  A Tier 1 assessment, which assumes all commodities of interest are treated and that residues are at tolerance level, was conducted and risks exceeded the level of concern for all population sub-groups.  The most highly exposed subgroup was Children, 1-2 years old, with an exposure estimate at 5500% of the  cPAD.  A more refined assessment was conducted using USDA PDP monitoring data for all commodities except rhubarb.  Reliable percent crop treated data are not available for crops receiving post-harvest treatments of DCNA, so all samples with non-detectable residues were assumed to have residues at the limit of detection (LOD), and no samples were assumed to have zero residues.  The exposures for all populations of interest were all below the level of concern in the refined analysis.  The most highly exposed subgroup was infants (<1 year old) with the exposure at 1.5% of the cPAD.

Table 4.  Summary of Dietary Exposure and Risk for Dicloran (DCNA) – Food Only

Population Subgroup	Acute Dietary	Chronic Dietary

	Tier 1 Assessment

95th Percentile	Refined Assessment

99.9th Percentile	Tier 1 Assessment	Refined Assessment

	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% cPAD 2	Dietary Exposure (mg/kg/day)	% cPAD 2

General U.S. Population	NA3	NA3	NA3	NA3	0.048	1900	0.00015	6.0

All Infants (< 1 year old) 	NA3	NA3	NA3	NA3	0.094	3700	0.00024	9.4

Children 1-2 years old	NA3	NA3	NA3	NA3	0.14	5500	0.00032	13

Children 3-5 years old	NA3	NA3	NA3	NA3	0.097	3900	0.00026	10

Children 6-12 years old	NA3	NA3	NA3	NA3	0.058	2300	0.00017	6.8

Youth 13-19 years old	NA3	NA3	NA3	NA3	0.037	1500	0.00012	4.8

Adults 20-49 years old	NA3	NA3	NA3	NA3	0.040	1600	0.00012	4.8

Adults 50+ years old	NA3	NA3	NA3	NA3	0.040	1600	0.00016	6.3

Females 13-49 years old	0.13	260	0.0049	9.9	0.039	1600	0.00012	4.8

The population sub-groups with the highest exposure are bolded.

1 aPAD = acute population adjusted dose

2 cPAD = chronic population adjusted dose

3 No appropriate endpoint has been identified for this population sub-group.

Table 5.  Summary of Dietary Exposure and Risk for Dicloran (DCNA) Incorporating Surface Water as a Drinking Water Source

Population Subgroup	Acute Dietary	Chronic Dietary

	Tier 1 Assessment

95th Percentile	Refined Assessment

99.9th Percentile	Tier 1 Assessment	Refined Assessment

	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% cPAD 2	Dietary Exposure (mg/kg/day)	% cPAD 2

General U.S. Population	NA3	NA3	NA3	NA3	0.048	1900	0.00019	7.5

All Infants (< 1 year old) 	NA3	NA3	NA3	NA3	0.094	3800	0.00036	14

Children 1-2 years old	NA3	NA3	NA3	NA3	0.14	5500	0.00038	15

Children 3-5 years old	NA3	NA3	NA3	NA3	0.10	3900	0.00031	12

Children 6-12 years old	NA3	NA3	NA3	NA3	0.058	2300	0.00021	8.2

Youth 13-19 years old	NA3	NA3	NA3	NA3	0.037	1500	0.00015	5.9

Adults 20-49 years old	NA3	NA3	NA3	NA3	0.040	1600	0.00016	6.3

Adults 50+ years old	NA3	NA3	NA3	NA3	0.040	1600	0.00019	7.7

Females 13-49 years old	0.13	270	0.026	52	0.039	1600	0.00016	6.2

The population sub-groups with the highest exposure are bolded.

1 aPAD = acute population adjusted dose

2 cPAD = chronic population adjusted dose

3 No appropriate endpoint has been identified for this population sub-group.

Table 6.  Summary of Dietary Exposure and Risk for Dicloran (DCNA) Incorporating Ground Water as a Drinking Water Source

Population Subgroup	Acute Dietary	Chronic Dietary

	Tier 1 Assessment

95th Percentile	Refined Assessment

99.9th Percentile	Tier 1 Assessment	Refined Assessment

	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% aPAD 1	Dietary Exposure (mg/kg/day)	% cPAD 2	Dietary Exposure (mg/kg/day)	% cPAD 2

General U.S. Population	NA3	NA3	NA3	NA3	0.048	1900	0.00018	7.1

All Infants (< 1 year old) 	NA3	NA3	NA3	NA3	0.094	3800	0.00033	13

Children 1-2 years old	NA3	NA3	NA3	NA3	0.14	5500	0.00036	14

Children 3-5 years old	NA3	NA3	NA3	NA3	0.097	3900	0.00030	12

Children 6-12 years old	NA3	NA3	NA3	NA3	0.058	2300	0.00020	7.8

Youth 13-19 years old	NA3	NA3	NA3	NA3	0.037	1500	0.00014	5.6

Adults 20-49 years old	NA3	NA3	NA3	NA3	0.040	1600	0.00015	5.9

Adults 50+ years old	NA3	NA3	NA3	NA3	0.040	1600	0.00018	7.3

Females 13-49 years old	0.13	260	0.0050	10	0.039	1600	0.00015	5.8

The population sub-groups with the highest exposure are bolded.

1 aPAD = acute population adjusted dose

2 cPAD = chronic population adjusted dose

3 No appropriate endpoint has been identified for this population sub-group.

VI.	Characterization of Inputs/Outputs

An uncertainty for both the acute and chronic analysis is the estimated residue for the metabolite DCHA and an unknown metabolite found in the potato metabolism study.  Since no field trial data are available for the DCHA metabolite and the unknown, residues were estimated using adjustment factors from the plant metabolism studies.  Considering that metabolism studies are conducted under carefully controlled conditions, the relative exposure to the metabolites is a reasonable estimate and is not likely to be a significant underestimate.  Also the commodities that have the highest residues in both field trial studies and monitoring data are those that receive post-harvest treatments.  There is minimal opportunity for significant DCNA conversion to the metabolite [on commodities treated post-harvest], so there is more overall exposure to the parent than the metabolites.

The refined acute and chronic dietary assessments used PDP monitoring data for all commodities with the exception of rhubarb.  The tolerance level used for the rhubarb is a high-end estimate, but the consumption of rhubarb is lower than most other commodities in the assessment, and is subsequently a low contributor to the exposure and risk.  PDP monitoring data are a much more realistic estimate of exposure than field trial data, but are still somewhat conservative because the samples were not subjected to any typical consumer preparation such as cooking.  Realistic post-harvest usage data were not available so the residue estimates for those commodities with the highest residues could not be refined using percent crop treated.  The LOD was used in calculating the residue average for all commodities bearing non-detectable residues.  This might be an overestimate of exposure, because it assumed all commodities had residues, though most were at very low levels.  Therefore, the assessment can be characterized as an over-estimate of exposure, and the actual exposure is likely to be much lower.  Using the PDP data as described to refine the acute assessment, the exposure for females 13-49, the only population sub-group for which an acute endpoint was identified, is at 10% of the aPAD.  For the chronic assessments, the most highly exposed sub-group is children (ages 1-2 years old) with exposures at 13-15% of the cPAD, which is considerably below the level of concern.  The general US population and most subgroups are at less than 10% of the cPAD.

Additional data that would refine the estimate would be usage data for the post-harvest treatments, field trial and/or monitoring data for the DCNA metabolites, and additional cooking and processing studies.

VII.	Conclusions

The acute and chronic dietary risks, including both food and water, were below the level of concern when PDP monitoring data were used to refine the assessments.  At the 99.9th percentile of exposure for females 13-49, the exposure was 9.9% of the aPAD for food alone and at 10% of the aPAD for food and water combined.  The chronic assessment resulted in food and water combined exposures at less than 10% of the cPAD for most population subgroups, and at 13-15% for the most highly exposed group, children (ages 1-2 years old).

VIII.		List of Attachments

Tier 1 Acute Residue Food Only Residue File

Tier 1 Acute Residue Food plus Surface Water Residue File

Tier 1 Acute Residue Food plus Ground Water Residue File

Refined Acute Residue Food Only Residue File

Refined Acute Residue Food plus Surface Water Residue File

Refined Acute Residue Food plus Ground Water Residue File

Tier 1 Acute Residue Food Only Results File

Tier 1 Acute Residue Food plus Surface Water Results File

Tier 1 Acute Residue Food plus Ground Water Results File

Refined Acute Residue Food Only Results File

Refined Acute Residue Food plus Surface Water Results File

Refined Acute Residue Food plus Ground Water Results File

Tier 1 Chronic Residue Food Only Residue File

Tier 1 Chronic Residue Food plus Surface Water Residue File

Tier 1 Chronic Residue Food plus Ground Water Residue File

Refined Chronic Residue Food Only Residue File

Refined Chronic Residue Food plus Surface Water Residue File

Refined Chronic Residue Food plus Ground Water Residue File

Tier 1 Chronic Residue Food Only Results File

Tier 1 Chronic Residue Food plus Surface Water Results File

Tier 1 Chronic Residue Food plus Ground Water Results File

Refined Chronic Residue Food Only Results File

Refined Chronic Residue Food plus Surface Water Results File

Refined Chronic Residue Food plus Ground Water Results File

cc:	Colinger

Tier 1 Acute Residue Food Only Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031031_a_tier1foodonly.R 98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-14-2006/13:55:23/8          Program ver. 2.03

Comment: tier1foodonly

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

12000120 12   Apricot                           20.000000   1.000  1.000

12000121 12   Apricot-babyfood                  20.000000   1.000  1.000

12000130 12   Apricot, dried                    20.000000   1.900  1.000

12000140 12   Apricot, juice                    20.000000   1.000  1.000

12000141 12   Apricot, juice-babyfood           20.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

06010430 6A   Bean, snap, succulent             20.000000   1.000  1.800

06010431 6A   Bean, snap, succulent-babyfood    20.000000   1.000  1.800

01010780 1AB  Carrot                            10.000000   1.000  1.000

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000

04020850 4B   Celery                            15.000000   1.000  1.000

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000

04020860 4B   Celery, juice                     15.000000   1.000  1.000

12000900 12   Cherry                            20.000000   1.000  1.000

12000901 12   Cherry-babyfood                   20.000000   1.000  1.000

12000910 12   Cherry, juice                     20.000000   1.500  1.000

12000911 12   Cherry, juice-babyfood            20.000000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

09021350 9B   Cucumber                           2.000000   1.000  1.800

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000

03001640 3    Garlic                             5.000000   1.000  7.500

03001650 3    Garlic, dried                      5.000000   1.000  7.500

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500

95001750 O    Grape                             10.000000   1.000  1.300

95001760 O    Grape, juice                      10.000000   1.300  1.300

95001761 O    Grape, juice-babyfood             10.000000   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300

95001780 O    Grape, raisin                     10.000000   1.000  1.300

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

12002300 12   Nectarine                         20.000000   1.000  1.000

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

12002600 12   Peach                             20.000000   1.000  1.000

12002601 12   Peach-babyfood                    20.000000   1.000  1.000

12002610 12   Peach, dried                      20.000000   1.900  1.000

12002611 12   Peach, dried-babyfood             20.000000   1.900  1.000

12002620 12   Peach, juice                      20.000000   1.000  1.000

12002621 12   Peach, juice-babyfood             20.000000   1.000  1.000

12002850 12   Plum                              15.000000   1.000  1.000

12002851 12   Plum-babyfood                     15.000000   1.000  1.000

12002860 12   Plum, prune, fresh                15.000000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood       15.000000   1.000  1.000

12002870 12   Plum, prune, dried                15.000000   1.900  1.000

12002871 12   Plum, prune, dried-babyfood       15.000000   1.900  1.000

12002880 12   Plum, prune, juice                15.000000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood       15.000000   1.400  1.000

01032960 1C   Potato, chips                      0.250000   1.000  7.500

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500

01032980 1C   Potato, flour                      0.250000   1.000  7.500

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500

04013130 4A   Radicchio                         10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500

01033660 1CD  Sweet potato                      10.000000   1.000  1.000

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000

08003750 8    Tomato                             5.000000   1.000  1.800

08003751 8    Tomato-babyfood                    5.000000   1.000  1.800

08003760 8    Tomato, paste                      5.000000   2.000  1.800

08003761 8    Tomato, paste-babyfood             5.000000   2.000  1.800

08003770 8    Tomato, puree                      5.000000   1.200  1.800

08003771 8    Tomato, puree-babyfood             5.000000   1.200  1.800

08003780 8    Tomato, dried                      5.000000  14.300  1.800

08003781 8    Tomato, dried-babyfood             5.000000  14.300  1.800

08003790 8    Tomato, juice                      5.000000   1.500  1.800

Tier 1 Acute Residue Food plus Surface Water Residue File

 Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031031_a_tier1surfacewat er.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-13-2006/14:41:51/8          Program ver. 2.03

Comment: Includes surface water; Tier 1

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

12000120 12   Apricot                           20.000000   1.000  1.000

12000121 12   Apricot-babyfood                  20.000000   1.000  1.000

12000130 12   Apricot, dried                    20.000000   1.900  1.000

12000140 12   Apricot, juice                    20.000000   1.000  1.000

12000141 12   Apricot, juice-babyfood           20.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

06010430 6A   Bean, snap, succulent             20.000000   1.000  1.800

06010431 6A   Bean, snap, succulent-babyfood    20.000000   1.000  1.800

01010780 1AB  Carrot                            10.000000   1.000  1.000

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000

04020850 4B   Celery                            15.000000   1.000  1.000

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000

04020860 4B   Celery, juice                     15.000000   1.000  1.000

12000900 12   Cherry                            20.000000   1.000  1.000

12000901 12   Cherry-babyfood                   20.000000   1.000  1.000

12000910 12   Cherry, juice                     20.000000   1.500  1.000

12000911 12   Cherry, juice-babyfood            20.000000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

09021350 9B   Cucumber                           2.000000   1.000  1.800

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000

03001640 3    Garlic                             5.000000   1.000  7.500

03001650 3    Garlic, dried                      5.000000   1.000  7.500

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500

95001750 O    Grape                             10.000000   1.000  1.300

95001760 O    Grape, juice                      10.000000   1.300  1.300

95001761 O    Grape, juice-babyfood             10.000000   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300

95001780 O    Grape, raisin                     10.000000   1.000  1.300

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

12002300 12   Nectarine                         20.000000   1.000  1.000

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

12002600 12   Peach                             20.000000   1.000  1.000

12002601 12   Peach-babyfood                    20.000000   1.000  1.000

12002610 12   Peach, dried                      20.000000   1.900  1.000

12002611 12   Peach, dried-babyfood             20.000000   1.900  1.000

12002620 12   Peach, juice                      20.000000   1.000  1.000

12002621 12   Peach, juice-babyfood             20.000000   1.000  1.000

12002850 12   Plum                              15.000000   1.000  1.000

12002851 12   Plum-babyfood                     15.000000   1.000  1.000

12002860 12   Plum, prune, fresh                15.000000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood       15.000000   1.000  1.000

12002870 12   Plum, prune, dried                15.000000   1.900  1.000

12002871 12   Plum, prune, dried-babyfood       15.000000   1.900  1.000

12002880 12   Plum, prune, juice                15.000000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood       15.000000   1.400  1.000

01032960 1C   Potato, chips                      0.250000   1.000  7.500

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500

01032980 1C   Potato, flour                      0.250000   1.000  7.500

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500

04013130 4A   Radicchio                         10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500

01033660 1CD  Sweet potato                      10.000000   1.000  1.000

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000

08003750 8    Tomato                             5.000000   1.000  1.800

08003751 8    Tomato-babyfood                    5.000000   1.000  1.800

08003760 8    Tomato, paste                      5.000000   2.000  1.800

08003761 8    Tomato, paste-babyfood             5.000000   2.000  1.800

08003770 8    Tomato, puree                      5.000000   1.200  1.800

08003771 8    Tomato, puree-babyfood             5.000000   1.200  1.800

08003780 8    Tomato, dried                      5.000000  14.300  1.800

08003781 8    Tomato, dried-babyfood             5.000000  14.300  1.800

08003790 8    Tomato, juice                      5.000000   1.500  1.800

86010000 O    Water, direct, all sources         0.173000   1.000  1.000

86020000 O    Water, indirect, all sources       0.173000   1.000  1.000

Tier 1 Acute Residue Food plus Ground Water Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031301_a_tier1groundwate r.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-13-2006/14:40:50/8          Program ver. 2.03

Comment: Ground water, Tier 1

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

12000120 12   Apricot                           20.000000   1.000  1.000

12000121 12   Apricot-babyfood                  20.000000   1.000  1.000

12000130 12   Apricot, dried                    20.000000   1.900  1.000

12000140 12   Apricot, juice                    20.000000   1.000  1.000

12000141 12   Apricot, juice-babyfood           20.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

06010430 6A   Bean, snap, succulent             20.000000   1.000  1.800

06010431 6A   Bean, snap, succulent-babyfood    20.000000   1.000  1.800

01010780 1AB  Carrot                            10.000000   1.000  1.000

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000

04020850 4B   Celery                            15.000000   1.000  1.000

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000

04020860 4B   Celery, juice                     15.000000   1.000  1.000

12000900 12   Cherry                            20.000000   1.000  1.000

12000901 12   Cherry-babyfood                   20.000000   1.000  1.000

12000910 12   Cherry, juice                     20.000000   1.500  1.000

12000911 12   Cherry, juice-babyfood            20.000000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

09021350 9B   Cucumber                           2.000000   1.000  1.800

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000

03001640 3    Garlic                             5.000000   1.000  7.500

03001650 3    Garlic, dried                      5.000000   1.000  7.500

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500

95001750 O    Grape                             10.000000   1.000  1.300

95001760 O    Grape, juice                      10.000000   1.300  1.300

95001761 O    Grape, juice-babyfood             10.000000   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300

95001780 O    Grape, raisin                     10.000000   1.000  1.300

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

12002300 12   Nectarine                         20.000000   1.000  1.000

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

12002600 12   Peach                             20.000000   1.000  1.000

12002601 12   Peach-babyfood                    20.000000   1.000  1.000

12002610 12   Peach, dried                      20.000000   1.900  1.000

12002611 12   Peach, dried-babyfood             20.000000   1.900  1.000

12002620 12   Peach, juice                      20.000000   1.000  1.000

12002621 12   Peach, juice-babyfood             20.000000   1.000  1.000

12002850 12   Plum                              15.000000   1.000  1.000

12002851 12   Plum-babyfood                     15.000000   1.000  1.000

12002860 12   Plum, prune, fresh                15.000000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood       15.000000   1.000  1.000

12002870 12   Plum, prune, dried                15.000000   1.900  1.000

12002871 12   Plum, prune, dried-babyfood       15.000000   1.900  1.000

12002880 12   Plum, prune, juice                15.000000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood       15.000000   1.400  1.000

01032960 1C   Potato, chips                      0.250000   1.000  7.500

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500

01032980 1C   Potato, flour                      0.250000   1.000  7.500

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500

04013130 4A   Radicchio                         10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500

01033660 1CD  Sweet potato                      10.000000   1.000  1.000

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000

08003750 8    Tomato                             5.000000   1.000  1.800

08003751 8    Tomato-babyfood                    5.000000   1.000  1.800

08003760 8    Tomato, paste                      5.000000   2.000  1.800

08003761 8    Tomato, paste-babyfood             5.000000   2.000  1.800

08003770 8    Tomato, puree                      5.000000   1.200  1.800

08003771 8    Tomato, puree-babyfood             5.000000   1.200  1.800

08003780 8    Tomato, dried                      5.000000  14.300  1.800

08003781 8    Tomato, dried-babyfood             5.000000  14.300  1.800

08003790 8    Tomato, juice                      5.000000   1.500  1.800

86010000 O    Water, direct, all sources         0.001300   1.000  1.000

86020000 O    Water, indirect, all sources       0.001300   1.000  1.000

Refined Acute Residue Food Only Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031031_p_foodonly.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-21-2006/15:31:19/8          Program ver. 2.03

Comment: Food only;  probabilistic

------------------------------------------------------------------------ --------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1        Param #2  Param #3  Comment

  #   Code

----- ---- ------------        --------  --------  -------

  1    6   cucumbers.rdf

  2    6   carrots.rdf

  3    6   celery.rdf

  4    6   grapes.rdf

  5    6   lettuce.rdf

  6    6   onions.rdf

  7    6   sweetpotatoes.rdf

  8    6   nectarines.rdf

  9    6   Peaches.rdf

  10   6   potatoes.rdf

  11   6   tomatoes.rdf

  12   6   cannedbeans.rdf

  13   6   beans.rdf

  EPA    Crop Commodity Name                    Def Res     Adj.Factors  RDL  Comment

  Code    Grp                                    (ppm)       #1     #2   Pntr

-------- ---- -------------------------------  ----------  ------ ------ ---  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000   5

12000120 12   Apricot

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 232-Cooked; Dried; Boiled      12.000000   1.900  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12000121 12   Apricot-babyfood                  12.000000   1.000  1.000   9

12000130 12   Apricot, dried                    12.000000   1.900  1.000   9

12000140 12   Apricot, juice                    12.000000   1.000  1.000   9

12000141 12   Apricot, juice-babyfood           12.000000   1.000  1.000   9

04010180 4A   Arugula                           12.000000   1.000  1.000   5

06010430 6A   Bean, snap, succulent

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 211-Cooked; Fresh or N/S; Baked

                                                 5.600000   1.000  1.800  13

                 212-Cooked; Fresh or N/S; Boiled

                                                 5.600000   1.000  1.800  13

                 213-Cooked; Fresh or N/S; Fried

                                                 5.600000   1.000  1.800  13

                 215-Cooked; Fresh or N/S; Boiled/baked

                                                 5.600000   1.000  1.800  13

                 221-Cooked; Frozen; Baked       5.600000   1.000  1.800  13

                 222-Cooked; Frozen; Boiled      5.600000   1.000  1.800  13

                 232-Cooked; Dried; Boiled       5.600000   1.000  1.800  13

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

                 242-Cooked; Canned; Boiled      5.600000   1.000  1.800  12

06010431 6A   Bean, snap, succulent-babyfood

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

01010780 1AB  Carrot                            10.000000   1.000  1.000   2

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000   2

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000   2

04020850 4B   Celery                            15.000000   1.000  1.000   3

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000   3

04020860 4B   Celery, juice                     15.000000   1.000  1.000   3

12000900 12   Cherry                             0.008000   1.000  1.000

12000901 12   Cherry-babyfood                    0.008000   1.000  1.000

12000910 12   Cherry, juice                      0.008000   1.500  1.000

12000911 12   Cherry, juice-babyfood             0.008000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000   5

04011330 4A   Cress, garden                     10.000000   1.000  1.000   5

04011340 4A   Cress, upland                     10.000000   1.000  1.000   5

09021350 9B   Cucumber                           2.000000   1.000  1.800   1

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000   5

04011500 4A   Endive                            10.000000   1.000  1.000   5

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000   3

03001640 3    Garlic                             5.000000   1.000  7.500   6

03001650 3    Garlic, dried                      5.000000   1.000  7.500   6

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500   6

95001750 O    Grape                             10.000000   1.000  1.300   4

95001760 O    Grape, juice                       0.009400   1.300  1.300

95001761 O    Grape, juice-babyfood              0.009400   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300   4

95001780 O    Grape, raisin                     10.000000   1.000  1.300   4

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300   4

04012040 4A   Lettuce, head                     10.000000   1.000  1.000   5

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000   5

12002300 12   Nectarine                          1.100000   1.000  1.000   8

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500   6

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500   6

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500   6

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500   6

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000   5

12002600 12   Peach

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 120-Uncooked; Frozen; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 130-Uncooked; Dried; Cook Meth N/S

                                                12.000000   1.900  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 223-Cooked; Frozen; Fried      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002601 12   Peach-babyfood                     0.009000   1.000  1.000

12002610 12   Peach, dried                      12.000000   1.900  1.000   9

12002611 12   Peach, dried-babyfood             12.000000   1.900  1.000   9

12002620 12   Peach, juice                      12.000000   1.000  1.000   9

12002621 12   Peach, juice-babyfood             12.000000   1.000  1.000   9

12002850 12   Plum

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002851 12   Plum-babyfood                     12.000000   1.000  1.000   9

12002860 12   Plum, prune, fresh                12.000000   1.000  1.000   9

12002861 12   Plum, prune, fresh-babyfood        0.009000   1.000  1.000

12002870 12   Plum, prune, dried                12.000000   1.900  1.000   9

12002871 12   Plum, prune, dried-babyfood       12.000000   1.900  1.000   9

12002880 12   Plum, prune, juice                12.000000   1.400  1.000   9

12002881 12   Plum, prune, juice-babyfood       12.000000   1.400  1.000   9

01032960 1C   Potato, chips                      0.250000   1.000  7.500  10

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500  10

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500  10

01032980 1C   Potato, flour                      0.250000   1.000  7.500  10

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500  10

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500  10

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500  10

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500  10

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500  10

04013130 4A   Radicchio                         10.000000   1.000  1.000   5

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500   6

01033660 1CD  Sweet potato                      10.000000   1.000  1.000   7

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000   7

08003750 8    Tomato                             0.620000   1.000  1.800  11

08003751 8    Tomato-babyfood                    0.620000   1.000  1.800  11

08003760 8    Tomato, paste                      0.006000   2.000  1.800

08003761 8    Tomato, paste-babyfood             0.006000   2.000  1.800

08003770 8    Tomato, puree                      0.007000   1.200  1.800

08003771 8    Tomato, puree-babyfood             0.007000   1.200  1.800

08003780 8    Tomato, dried                      0.620000  14.300  1.800  11

08003781 8    Tomato, dried-babyfood             0.620000  14.300  1.800  11

08003790 8    Tomato, juice                      0.620000   1.500  1.800  11

Refined Acute Residue Food plus Surface Water Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031031_p_surfacewater.R9 8

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-21-2006/15:30:27/8          Program ver. 2.03

Comment: Includes surface water

------------------------------------------------------------------------ --------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1        Param #2  Param #3  Comment

  #   Code

----- ---- ------------        --------  --------  -------

  1    6   cucumbers.rdf

  2    6   carrots.rdf

  3    6   celery.rdf

  4    6   grapes.rdf

  5    6   lettuce.rdf

  6    6   onions.rdf

  7    6   sweetpotatoes.rdf

  8    6   nectarines.rdf

  9    6   Peaches.rdf

  10   6   potatoes.rdf

  11   6   tomatoes.rdf

  12   6   cannedbeans.rdf

  13   6   beans.rdf

  EPA    Crop Commodity Name                    Def Res     Adj.Factors  RDL  Comment

  Code    Grp                                    (ppm)       #1     #2   Pntr

-------- ---- -------------------------------  ----------  ------ ------ ---  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000   5

12000120 12   Apricot

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 232-Cooked; Dried; Boiled      12.000000   1.900  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12000121 12   Apricot-babyfood                  12.000000   1.000  1.000   9

12000130 12   Apricot, dried                    12.000000   1.900  1.000   9

12000140 12   Apricot, juice                    12.000000   1.000  1.000   9

12000141 12   Apricot, juice-babyfood           12.000000   1.000  1.000   9

04010180 4A   Arugula                           12.000000   1.000  1.000   5

06010430 6A   Bean, snap, succulent

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 211-Cooked; Fresh or N/S; Baked

                                                 5.600000   1.000  1.800  13

                 212-Cooked; Fresh or N/S; Boiled

                                                 5.600000   1.000  1.800  13

                 213-Cooked; Fresh or N/S; Fried

                                                 5.600000   1.000  1.800  13

                 215-Cooked; Fresh or N/S; Boiled/baked

                                                 5.600000   1.000  1.800  13

                 221-Cooked; Frozen; Baked       5.600000   1.000  1.800  13

                 222-Cooked; Frozen; Boiled      5.600000   1.000  1.800  13

                 232-Cooked; Dried; Boiled       5.600000   1.000  1.800  13

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

                 242-Cooked; Canned; Boiled      5.600000   1.000  1.800  12

06010431 6A   Bean, snap, succulent-babyfood

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

01010780 1AB  Carrot                            10.000000   1.000  1.000   2

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000   2

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000   2

04020850 4B   Celery                            15.000000   1.000  1.000   3

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000   3

04020860 4B   Celery, juice                     15.000000   1.000  1.000   3

12000900 12   Cherry                             0.008000   1.000  1.000

12000901 12   Cherry-babyfood                    0.008000   1.000  1.000

12000910 12   Cherry, juice                      0.008000   1.500  1.000

12000911 12   Cherry, juice-babyfood             0.008000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000   5

04011330 4A   Cress, garden                     10.000000   1.000  1.000   5

04011340 4A   Cress, upland                     10.000000   1.000  1.000   5

09021350 9B   Cucumber                           2.000000   1.000  1.800   1

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000   5

04011500 4A   Endive                            10.000000   1.000  1.000   5

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000   3

03001640 3    Garlic                             5.000000   1.000  7.500   6

03001650 3    Garlic, dried                      5.000000   1.000  7.500   6

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500   6

95001750 O    Grape                             10.000000   1.000  1.300   4

95001760 O    Grape, juice                       0.009400   1.300  1.300

95001761 O    Grape, juice-babyfood              0.009400   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300   4

95001780 O    Grape, raisin                     10.000000   1.000  1.300   4

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300   4

04012040 4A   Lettuce, head                     10.000000   1.000  1.000   5

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000   5

12002300 12   Nectarine                          1.100000   1.000  1.000   8

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500   6

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500   6

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500   6

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500   6

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000   5

12002600 12   Peach

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 120-Uncooked; Frozen; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 130-Uncooked; Dried; Cook Meth N/S

                                                12.000000   1.900  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 223-Cooked; Frozen; Fried      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002601 12   Peach-babyfood                     0.009000   1.000  1.000

12002610 12   Peach, dried                      12.000000   1.900  1.000   9

12002611 12   Peach, dried-babyfood             12.000000   1.900  1.000   9

12002620 12   Peach, juice                      12.000000   1.000  1.000   9

12002621 12   Peach, juice-babyfood             12.000000   1.000  1.000   9

12002850 12   Plum

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002851 12   Plum-babyfood                     12.000000   1.000  1.000   9

12002860 12   Plum, prune, fresh                12.000000   1.000  1.000   9

12002861 12   Plum, prune, fresh-babyfood        0.009000   1.000  1.000

12002870 12   Plum, prune, dried                12.000000   1.900  1.000   9

12002871 12   Plum, prune, dried-babyfood       12.000000   1.900  1.000   9

12002880 12   Plum, prune, juice                12.000000   1.400  1.000   9

12002881 12   Plum, prune, juice-babyfood       12.000000   1.400  1.000   9

01032960 1C   Potato, chips                      0.250000   1.000  7.500  10

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500  10

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500  10

01032980 1C   Potato, flour                      0.250000   1.000  7.500  10

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500  10

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500  10

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500  10

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500  10

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500  10

04013130 4A   Radicchio                         10.000000   1.000  1.000   5

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500   6

01033660 1CD  Sweet potato                      10.000000   1.000  1.000   7

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000   7

08003750 8    Tomato                             0.620000   1.000  1.800  11

08003751 8    Tomato-babyfood                    0.620000   1.000  1.800  11

08003760 8    Tomato, paste                      0.006000   2.000  1.800

08003761 8    Tomato, paste-babyfood             0.006000   2.000  1.800

08003770 8    Tomato, puree                      0.007000   1.200  1.800

08003771 8    Tomato, puree-babyfood             0.007000   1.200  1.800

08003780 8    Tomato, dried                      0.620000  14.300  1.800  11

08003781 8    Tomato, dried-babyfood             0.620000  14.300  1.800  11

08003790 8    Tomato, juice                      0.620000   1.500  1.800  11

86010000 O    Water, direct, all sources         0.173000   1.000  1.000

86020000 O    Water, indirect, all sources       0.173000   1.000  1.000

Refined Acute Residue Food plus Ground Water Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031031_p_groundwater.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-21-2006/15:29:33/8          Program ver. 2.03

Comment: Includes groundwater;

------------------------------------------------------------------------ --------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1        Param #2  Param #3  Comment

  #   Code

----- ---- ------------        --------  --------  -------

  1    6   cucumbers.rdf

  2    6   carrots.rdf

  3    6   celery.rdf

  4    6   grapes.rdf

  5    6   lettuce.rdf

  6    6   onions.rdf

  7    6   sweetpotatoes.rdf

  8    6   nectarines.rdf

  9    6   Peaches.rdf

  10   6   potatoes.rdf

  11   6   tomatoes.rdf

  12   6   cannedbeans.rdf

  13   6   beans.rdf

  EPA    Crop Commodity Name                    Def Res     Adj.Factors  RDL  Comment

  Code    Grp                                    (ppm)       #1     #2   Pntr

-------- ---- -------------------------------  ----------  ------ ------ ---  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000   5

12000120 12   Apricot

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 232-Cooked; Dried; Boiled      12.000000   1.900  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12000121 12   Apricot-babyfood                  12.000000   1.000  1.000   9

12000130 12   Apricot, dried                    12.000000   1.900  1.000   9

12000140 12   Apricot, juice                    12.000000   1.000  1.000   9

12000141 12   Apricot, juice-babyfood           12.000000   1.000  1.000   9

04010180 4A   Arugula                           12.000000   1.000  1.000   5

06010430 6A   Bean, snap, succulent

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                 5.600000   1.000  1.800  13

                 211-Cooked; Fresh or N/S; Baked

                                                 5.600000   1.000  1.800  13

                 212-Cooked; Fresh or N/S; Boiled

                                                 5.600000   1.000  1.800  13

                 213-Cooked; Fresh or N/S; Fried

                                                 5.600000   1.000  1.800  13

                 215-Cooked; Fresh or N/S; Boiled/baked

                                                 5.600000   1.000  1.800  13

                 221-Cooked; Frozen; Baked       5.600000   1.000  1.800  13

                 222-Cooked; Frozen; Boiled      5.600000   1.000  1.800  13

                 232-Cooked; Dried; Boiled       5.600000   1.000  1.800  13

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

                 242-Cooked; Canned; Boiled      5.600000   1.000  1.800  12

06010431 6A   Bean, snap, succulent-babyfood

                 240-Cooked; Canned; Cook Meth N/S

                                                 5.600000   1.000  1.800  12

01010780 1AB  Carrot                            10.000000   1.000  1.000   2

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000   2

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000   2

04020850 4B   Celery                            15.000000   1.000  1.000   3

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000   3

04020860 4B   Celery, juice                     15.000000   1.000  1.000   3

12000900 12   Cherry                             0.008000   1.000  1.000

12000901 12   Cherry-babyfood                    0.008000   1.000  1.000

12000910 12   Cherry, juice                      0.008000   1.500  1.000

12000911 12   Cherry, juice-babyfood             0.008000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000   5

04011330 4A   Cress, garden                     10.000000   1.000  1.000   5

04011340 4A   Cress, upland                     10.000000   1.000  1.000   5

09021350 9B   Cucumber                           2.000000   1.000  1.800   1

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000   5

04011500 4A   Endive                            10.000000   1.000  1.000   5

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000   3

03001640 3    Garlic                             5.000000   1.000  7.500   6

03001650 3    Garlic, dried                      5.000000   1.000  7.500   6

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500   6

95001750 O    Grape                             10.000000   1.000  1.300   4

95001760 O    Grape, juice                       0.009400   1.300  1.300

95001761 O    Grape, juice-babyfood              0.009400   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300   4

95001780 O    Grape, raisin                     10.000000   1.000  1.300   4

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300   4

04012040 4A   Lettuce, head                     10.000000   1.000  1.000   5

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000   5

12002300 12   Nectarine                          1.100000   1.000  1.000   8

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500   6

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500   6

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500   6

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500   6

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000   5

12002600 12   Peach

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 120-Uncooked; Frozen; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 130-Uncooked; Dried; Cook Meth N/S

                                                12.000000   1.900  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 213-Cooked; Fresh or N/S; Fried

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 223-Cooked; Frozen; Fried      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002601 12   Peach-babyfood                     0.009000   1.000  1.000

12002610 12   Peach, dried                      12.000000   1.900  1.000   9

12002611 12   Peach, dried-babyfood             12.000000   1.900  1.000   9

12002620 12   Peach, juice                      12.000000   1.000  1.000   9

12002621 12   Peach, juice-babyfood             12.000000   1.000  1.000   9

12002850 12   Plum

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 210-Cooked; Fresh or N/S; Cook Meth N/S

                                                12.000000   1.000  1.000   9

                 211-Cooked; Fresh or N/S; Baked

                                                12.000000   1.000  1.000   9

                 221-Cooked; Frozen; Baked      12.000000   1.000  1.000   9

                 240-Cooked; Canned; Cook Meth N/S

                                                 0.009000   1.000  1.000

12002851 12   Plum-babyfood                     12.000000   1.000  1.000   9

12002860 12   Plum, prune, fresh                12.000000   1.000  1.000   9

12002861 12   Plum, prune, fresh-babyfood        0.009000   1.000  1.000

12002870 12   Plum, prune, dried                12.000000   1.900  1.000   9

12002871 12   Plum, prune, dried-babyfood       12.000000   1.900  1.000   9

12002880 12   Plum, prune, juice                12.000000   1.400  1.000   9

12002881 12   Plum, prune, juice-babyfood       12.000000   1.400  1.000   9

01032960 1C   Potato, chips                      0.250000   1.000  7.500  10

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500  10

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500  10

01032980 1C   Potato, flour                      0.250000   1.000  7.500  10

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500  10

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500  10

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500  10

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500  10

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500  10

04013130 4A   Radicchio                         10.000000   1.000  1.000   5

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500   6

01033660 1CD  Sweet potato                      10.000000   1.000  1.000   7

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000   7

08003750 8    Tomato                             0.620000   1.000  1.800  11

08003751 8    Tomato-babyfood                    0.620000   1.000  1.800  11

08003760 8    Tomato, paste                      0.006000   2.000  1.800

08003761 8    Tomato, paste-babyfood             0.006000   2.000  1.800

08003770 8    Tomato, puree                      0.007000   1.200  1.800

08003771 8    Tomato, puree-babyfood             0.007000   1.200  1.800

08003780 8    Tomato, dried                      0.620000  14.300  1.800  11

08003781 8    Tomato, dried-babyfood             0.620000  14.300  1.800  11

08003790 8    Tomato, juice                      0.620000   1.500  1.800  11

86010000 O    Water, direct, all sources         0.001300   1.000  1.000

86020000 O    Water, indirect, all sources       0.001300   1.000  1.000

Tier 1 Acute Residue Food Only Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1foodonly.R98              Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:17:42    Residue file dated: 02-27-2006/14:57:20/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Food Only; Tier 1"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.131292  262.58     380    0.199224  398.45     250    0.325183  650.37     153

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1foodonly.R98              Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:17:42    Residue file dated: 02-27-2006/14:57:20/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Food Only; Tier 1"

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.041902     0.042983

            Standard Deviation        0.045147     0.045215

            Standard Error of mean    0.000589     0.000598

            Margin of Exposure 2/        1,193        1,163

            Percent of aRfD              83.80        85.97

       Percent of Person-Days that are User-Days =  97.49%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.003599     7.20     13,890   90.00    0.100152   200.30        499

20.00     0.008460    16.92      5,909   95.00    0.132769   265.54        376

30.00     0.014447    28.89      3,461   97.50    0.160113   320.23        312

40.00     0.020954    41.91      2,386   99.00    0.199973   399.95        250

50.00     0.029028    58.06      1,722   99.50    0.228647   457.29        218

60.00     0.039021    78.04      1,281   99.75    0.277870   555.74        179

70.00     0.052109   104.22        959   99.90    0.325674   651.35        153

80.00     0.071028   142.06        703

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.002511     5.02     19,911   90.00    0.098886   197.77        505

20.00     0.007317    14.63      6,833   95.00    0.131292   262.58        380

30.00     0.013137    26.27      3,806   97.50    0.159011   318.02        314

40.00     0.019856    39.71      2,518   99.00    0.199224   398.45        250

50.00     0.027760    55.52      1,801   99.50    0.228422   456.84        218

60.00     0.037756    75.51      1,324   99.75    0.277269   554.54        180

70.00     0.051123   102.25        978   99.90    0.325183   650.37        153

80.00     0.069697   139.39        717

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98 survey.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Tier 1 Acute Residue Food plus Surface Water Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1surfacewater.R98          Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:19:35    Residue file dated: 02-27-2006/14:53:05/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Includes surface water; Tier 1"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.134884  269.77     370    0.204222  408.44     244    0.330016  660.03     151

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1surfacewater.R98          Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:19:35    Residue file dated: 02-27-2006/14:53:05/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Includes surface water; Tier 1"

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.045332     0.045376

            Standard Deviation        0.045543     0.045543

            Standard Error of mean    0.000596     0.000596

            Margin of Exposure 2/        1,102        1,101

            Percent of aRfD              90.66        90.75

       Percent of Person-Days that are User-Days =  99.90%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.005522    11.04      9,054   90.00    0.103367   206.73        483

20.00     0.010685    21.37      4,679   95.00    0.134926   269.85        370

30.00     0.016247    32.49      3,077   97.50    0.162405   324.81        307

40.00     0.023508    47.02      2,126   99.00    0.204243   408.49        244

50.00     0.031590    63.18      1,582   99.50    0.231772   463.54        215

60.00     0.041307    82.61      1,210   99.75    0.283741   567.48        176

70.00     0.054674   109.35        914   99.90    0.330035   660.07        151

80.00     0.073062   146.12        684

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.005479    10.96      9,126   90.00    0.103323   206.65        483

20.00     0.010646    21.29      4,696   95.00    0.134884   269.77        370

30.00     0.016215    32.43      3,083   97.50    0.162367   324.73        307

40.00     0.023459    46.92      2,131   99.00    0.204222   408.44        244

50.00     0.031553    63.11      1,584   99.50    0.231762   463.52        215

60.00     0.041269    82.54      1,211   99.75    0.283728   567.46        176

70.00     0.054624   109.25        915   99.90    0.330016   660.03        151

80.00     0.073024   146.05        684

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98

   with 2 days of valid drinking water records.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Tier 1 Acute Residue Food plus Ground Water Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1groundwater.R98           Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:18:51    Residue file dated: 02-27-2006/14:56:06/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Ground water, Tier 1"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.131543  263.09     380    0.199262  398.52     250    0.327549  655.10     152

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_a_tier1groundwater.R98           Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:18:51    Residue file dated: 02-27-2006/14:56:06/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

Run Comment: "Ground water, Tier 1"

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.041966     0.042006

            Standard Deviation        0.045203     0.045206

            Standard Error of mean    0.000592     0.000592

            Margin of Exposure 2/        1,191        1,190

            Percent of aRfD              83.93        84.01

       Percent of Person-Days that are User-Days =  99.90%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.002562     5.12     19,518   90.00    0.098908   197.82        505

20.00     0.007444    14.89      6,716   95.00    0.131594   263.19        379

30.00     0.013265    26.53      3,769   97.50    0.159207   318.41        314

40.00     0.019966    39.93      2,504   99.00    0.199291   398.58        250

50.00     0.027852    55.70      1,795   99.50    0.229953   459.91        217

60.00     0.037785    75.57      1,323   99.75    0.276591   553.18        180

70.00     0.051187   102.37        976   99.90    0.327568   655.14        152

80.00     0.069648   139.30        717

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.002524     5.05     19,809   90.00    0.098869   197.74        505

20.00     0.007401    14.80      6,755   95.00    0.131543   263.09        380

30.00     0.013220    26.44      3,782   97.50    0.159153   318.31        314

40.00     0.019921    39.84      2,509   99.00    0.199262   398.52        250

50.00     0.027808    55.62      1,798   99.50    0.229941   459.88        217

60.00     0.037747    75.49      1,324   99.75    0.276568   553.14        180

70.00     0.051152   102.30        977   99.90    0.327549   655.10        152

80.00     0.069577   139.15        718

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98

   with 2 days of valid drinking water records.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Refined Acute Residue Food Only Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_foodonly.R98                   Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:22:57    Residue file dated: 02-27-2006/14:18:56/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Food only;  probabilistic"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.000308    0.62  162568    0.000738    1.48   67736    0.004926    9.85   10149

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_foodonly.R98                   Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:22:57    Residue file dated: 02-27-2006/14:18:56/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Food only;  probabilistic"

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.000121     0.000124

            Standard Deviation        0.000748     0.000757

            Margin of Exposure 2/      412,051      401,688

            Percent of aRfD               0.24         0.25

       Percent of Person-Days that are User-Days =  97.49%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000007     0.01 >1,000,000   90.00    0.000226     0.45    221,332

20.00     0.000018     0.04 >1,000,000   95.00    0.000312     0.62    160,116

30.00     0.000031     0.06 >1,000,000   97.50    0.000440     0.88    113,727

40.00     0.000046     0.09 >1,000,000   99.00    0.000756     1.51     66,123

50.00     0.000065     0.13    773,057   99.50    0.001417     2.83     35,291

60.00     0.000086     0.17    582,479   99.75    0.002463     4.93     20,302

70.00     0.000112     0.22    446,601   99.90    0.005022    10.04      9,956

80.00     0.000151     0.30    330,614

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000005     0.01 >1,000,000   90.00    0.000223     0.45    224,064

20.00     0.000016     0.03 >1,000,000   95.00    0.000308     0.62    162,568

30.00     0.000029     0.06 >1,000,000   97.50    0.000435     0.87    114,976

40.00     0.000044     0.09 >1,000,000   99.00    0.000738     1.48     67,736

50.00     0.000062     0.12    808,483   99.50    0.001384     2.77     36,132

60.00     0.000083     0.17    602,609   99.75    0.002401     4.80     20,823

70.00     0.000110     0.22    455,019   99.90    0.004926     9.85     10,149

80.00     0.000149     0.30    335,864

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98 survey.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Refined Acute Residue Food Plus Surface Water Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_surfacewater.R98               Adjustment factor #2 used.

Analysis Date: 03-09-2006/13:35:14    Residue file dated: 03-09-2006/13:27:08/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Includes surface water"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.008592   17.18    5819    0.013977   27.95    3577    0.025780   51.56    1939

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_surfacewater.R98               Adjustment factor #2 used.

Analysis Date: 03-09-2006/13:35:14    Residue file dated: 03-09-2006/13:27:08/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Includes surface water"

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.003513     0.003516

            Standard Deviation        0.002981     0.002980

            Margin of Exposure 2/       14,233       14,219

            Percent of aRfD               7.03         7.03

       Percent of Person-Days that are User-Days =  99.90%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000761     1.52     65,708   90.00    0.006874    13.75      7,274

20.00     0.001342     2.68     37,263   95.00    0.008594    17.19      5,818

30.00     0.001828     3.66     27,358   97.50    0.010767    21.53      4,643

40.00     0.002333     4.67     21,428   99.00    0.013980    27.96      3,576

50.00     0.002882     5.76     17,349   99.50    0.017453    34.91      2,864

60.00     0.003474     6.95     14,392   99.75    0.019921    39.84      2,509

70.00     0.004178     8.36     11,966   99.90    0.025782    51.56      1,939

80.00     0.005220    10.44      9,578

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000756     1.51     66,110   90.00    0.006871    13.74      7,277

20.00     0.001336     2.67     37,438   95.00    0.008592    17.18      5,819

30.00     0.001825     3.65     27,399   97.50    0.010765    21.53      4,644

40.00     0.002330     4.66     21,457   99.00    0.013977    27.95      3,577

50.00     0.002879     5.76     17,365   99.50    0.017451    34.90      2,865

60.00     0.003471     6.94     14,403   99.75    0.019917    39.83      2,510

70.00     0.004176     8.35     11,972   99.90    0.025780    51.56      1,939

80.00     0.005218    10.44      9,582

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98

   with 2 days of valid drinking water records.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Refined Acute Residue Food Plus Ground Water Results File

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_groundwater.R98                Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:31:38    Residue file dated: 02-27-2006/14:22:40/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Includes groundwater; "

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Females 13-49 yrs:

  0.000338    0.68  147799    0.000778    1.56   64290    0.004993    9.99   10015

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for DCNA (DICLORAN, DICHLOROANILINE)    (1994-98 data)

Residue file: 031301_p_groundwater.R98                Adjustment factor #2 used.

Analysis Date: 02-27-2006/15:31:38    Residue file dated: 02-27-2006/14:22:40/8

NOEL (Acute) =  50.000000 mg/kg body-wt/day

Acute Reference Dose (aRfD) =   0.050000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Includes groundwater; "

======================================================================== =======

Females 13-49 yrs                  Daily Exposure Analysis  /a

-----------------                  (mg/kg body-weight/day)

                                    per Capita    per User

                                   -----------  -----------

            Mean                      0.000147     0.000147

            Standard Deviation        0.000749     0.000750

            Margin of Exposure 2/      340,738      340,407

            Percent of aRfD               0.29         0.29

       Percent of Person-Days that are User-Days =  99.90%

  Estimated percentile of user-days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000025     0.05 >1,000,000   90.00    0.000252     0.50    198,798

20.00     0.000040     0.08 >1,000,000   95.00    0.000338     0.68    147,725

30.00     0.000054     0.11    924,666   97.50    0.000472     0.94    106,038

40.00     0.000071     0.14    704,491   99.00    0.000778     1.56     64,266

50.00     0.000088     0.18    570,273   99.50    0.001432     2.86     34,921

60.00     0.000110     0.22    455,439   99.75    0.002439     4.88     20,499

70.00     0.000137     0.27    364,122   99.90    0.004998    10.00     10,004

80.00     0.000178     0.36    281,202

  Estimated percentile of per-capita days falling below calculated exposure

    in mg/kg body-wt/day with Margin of Exposure (MOE) and Percent of aRfD

Perc.   Exposure    % aRfD     MOE       Perc.  Exposure    % aRfD      MOE

-----  -----------  ------- ----------   ----- -----------  -------  ---------

10.00     0.000025     0.05 >1,000,000   90.00    0.000251     0.50    198,889

20.00     0.000039     0.08 >1,000,000   95.00    0.000338     0.68    147,799

30.00     0.000054     0.11    926,254   97.50    0.000471     0.94    106,144

40.00     0.000071     0.14    705,589   99.00    0.000778     1.56     64,290

50.00     0.000088     0.18    570,786   99.50    0.001430     2.86     34,955

60.00     0.000110     0.22    455,850   99.75    0.002437     4.87     20,518

70.00     0.000137     0.27    364,349   99.90    0.004993     9.99     10,015

80.00     0.000178     0.36    281,328

------------------------------------------------------------------------ -------

a/ Analysis based on all two-day participant records in CSFII 1994-98

   with 2 days of valid drinking water records.

2/ Margin of Exposure = NOEL/ Dietary Exposure.

                                      1

Tier 1 Chronic Residue Food Only Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031301_c_tier1foodonly.R 98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-14-2006/13:57:49/8          Program ver. 2.03

Comment: Food Only Tier 1

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

12000120 12   Apricot                           20.000000   1.000  1.000

12000121 12   Apricot-babyfood                  20.000000   1.000  1.000

12000130 12   Apricot, dried                    20.000000   1.900  1.000

12000140 12   Apricot, juice                    20.000000   1.000  1.000

12000141 12   Apricot, juice-babyfood           20.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

06010430 6A   Bean, snap, succulent             20.000000   1.000  1.800

06010431 6A   Bean, snap, succulent-babyfood    20.000000   1.000  1.800

01010780 1AB  Carrot                            10.000000   1.000  1.000

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000

04020850 4B   Celery                            15.000000   1.000  1.000

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000

04020860 4B   Celery, juice                     15.000000   1.000  1.000

12000900 12   Cherry                            20.000000   1.000  1.000

12000901 12   Cherry-babyfood                   20.000000   1.000  1.000

12000910 12   Cherry, juice                     20.000000   1.500  1.000

12000911 12   Cherry, juice-babyfood            20.000000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

09021350 9B   Cucumber                           2.000000   1.000  1.800

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000

03001640 3    Garlic                             5.000000   1.000  7.500

03001650 3    Garlic, dried                      5.000000   1.000  7.500

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500

95001750 O    Grape                             10.000000   1.000  1.300

95001760 O    Grape, juice                      10.000000   1.300  1.300

95001761 O    Grape, juice-babyfood             10.000000   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300

95001780 O    Grape, raisin                     10.000000   1.000  1.300

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

12002300 12   Nectarine                         20.000000   1.000  1.000

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

12002600 12   Peach                             20.000000   1.000  1.000

12002601 12   Peach-babyfood                    20.000000   1.000  1.000

12002610 12   Peach, dried                      20.000000   1.900  1.000

12002611 12   Peach, dried-babyfood             20.000000   1.900  1.000

12002620 12   Peach, juice                      20.000000   1.000  1.000

12002621 12   Peach, juice-babyfood             20.000000   1.000  1.000

12002850 12   Plum                              15.000000   1.000  1.000

12002851 12   Plum-babyfood                     15.000000   1.000  1.000

12002860 12   Plum, prune, fresh                15.000000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood       15.000000   1.000  1.000

12002870 12   Plum, prune, dried                15.000000   1.900  1.000

12002871 12   Plum, prune, dried-babyfood       15.000000   1.900  1.000

12002880 12   Plum, prune, juice                15.000000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood       15.000000   1.400  1.000

01032960 1C   Potato, chips                      0.250000   1.000  7.500

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500

01032980 1C   Potato, flour                      0.250000   1.000  7.500

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500

04013130 4A   Radicchio                         10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500

01033660 1CD  Sweet potato                      10.000000   1.000  1.000

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000

08003750 8    Tomato                             5.000000   1.000  1.000

08003751 8    Tomato-babyfood                    5.000000   1.000  1.000

08003760 8    Tomato, paste                      5.000000   2.000  1.000

08003761 8    Tomato, paste-babyfood             5.000000   2.000  1.000

08003770 8    Tomato, puree                      5.000000   1.200  1.000

08003771 8    Tomato, puree-babyfood             5.000000   1.200  1.000

08003780 8    Tomato, dried                      5.000000  14.300  1.000

08003781 8    Tomato, dried-babyfood             5.000000  14.300  1.000

08003790 8    Tomato, juice                      5.000000   1.500  1.000

Tier 1 Chronic Residue Food plus Surface Water Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031301_c_tier1surfacewat er.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-13-2006/14:45:09/8          Program ver. 2.03

Comment: Surface Water;  Tier 1

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

04010050 4A   Amaranth, leafy                   10.000000   1.000  1.000

12000120 12   Apricot                           20.000000   1.000  1.000

12000121 12   Apricot-babyfood                  20.000000   1.000  1.000

12000130 12   Apricot, dried                    20.000000   1.900  1.000

12000140 12   Apricot, juice                    20.000000   1.000  1.000

12000141 12   Apricot, juice-babyfood           20.000000   1.000  1.000

04010180 4A   Arugula                           10.000000   1.000  1.000

06010430 6A   Bean, snap, succulent             20.000000   1.000  1.800

06010431 6A   Bean, snap, succulent-babyfood    20.000000   1.000  1.800

01010780 1AB  Carrot                            10.000000   1.000  1.000

01010781 1AB  Carrot-babyfood                   10.000000   1.000  1.000

01010790 1AB  Carrot, juice                     10.000000   1.000  1.000

04020850 4B   Celery                            15.000000   1.000  1.000

04020851 4B   Celery-babyfood                   15.000000   1.000  1.000

04020860 4B   Celery, juice                     15.000000   1.000  1.000

12000900 12   Cherry                            20.000000   1.000  1.000

12000901 12   Cherry-babyfood                   20.000000   1.000  1.000

12000910 12   Cherry, juice                     20.000000   1.500  1.000

12000911 12   Cherry, juice-babyfood            20.000000   1.500  1.000

04011040 4A   Chrysanthemum, garland            10.000000   1.000  1.000

04011330 4A   Cress, garden                     10.000000   1.000  1.000

04011340 4A   Cress, upland                     10.000000   1.000  1.000

09021350 9B   Cucumber                           2.000000   1.000  1.800

04011380 4A   Dandelion, leaves                 10.000000   1.000  1.000

04011500 4A   Endive                            10.000000   1.000  1.000

04021520 4B   Fennel, Florence                  15.000000   1.000  1.000

03001640 3    Garlic                             5.000000   1.000  7.500

03001650 3    Garlic, dried                      5.000000   1.000  7.500

03001651 3    Garlic, dried-babyfood             5.000000   1.000  7.500

95001750 O    Grape                             10.000000   1.000  1.300

95001760 O    Grape, juice                      10.000000   1.300  1.300

95001761 O    Grape, juice-babyfood             10.000000   1.300  1.300

95001770 O    Grape, leaves                     10.000000   1.000  1.300

95001780 O    Grape, raisin                     10.000000   1.000  1.300

95001790 O    Grape, wine and sherry            10.000000   1.000  1.300

04012040 4A   Lettuce, head                     10.000000   1.000  1.000

04012050 4A   Lettuce, leaf                     10.000000   1.000  1.000

12002300 12   Nectarine                         20.000000   1.000  1.000

03002370 3    Onion, dry bulb                   10.000000   1.000  7.500

03002371 3    Onion, dry bulb-babyfood          10.000000   1.000  7.500

03002380 3    Onion, dry bulb, dried            10.000000   9.000  7.500

03002381 3    Onion, dry bulb, dried-babyfood   10.000000   9.000  7.500

04012480 4A   Parsley, leaves                   10.000000   1.000  1.000

12002600 12   Peach                             20.000000   1.000  1.000

12002601 12   Peach-babyfood                    20.000000   1.000  1.000

12002610 12   Peach, dried                      20.000000   1.900  1.000

12002611 12   Peach, dried-babyfood             20.000000   1.900  1.000

12002620 12   Peach, juice                      20.000000   1.000  1.000

12002621 12   Peach, juice-babyfood             20.000000   1.000  1.000

12002850 12   Plum                              15.000000   1.000  1.000

12002851 12   Plum-babyfood                     15.000000   1.000  1.000

12002860 12   Plum, prune, fresh                15.000000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood       15.000000   1.000  1.000

12002870 12   Plum, prune, dried                15.000000   1.900  1.000

12002871 12   Plum, prune, dried-babyfood       15.000000   1.900  1.000

12002880 12   Plum, prune, juice                15.000000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood       15.000000   1.400  1.000

01032960 1C   Potato, chips                      0.250000   1.000  7.500

01032970 1C   Potato, dry (granules/ flakes)     0.250000   6.500  7.500

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   6.500  7.500

01032980 1C   Potato, flour                      0.250000   1.000  7.500

01032981 1C   Potato, flour-babyfood             0.250000   1.000  7.500

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  7.500

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  7.500

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  7.500

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  7.500

04013130 4A   Radicchio                         10.000000   1.000  1.000

04023220 4B   Rhubarb                           10.000000   1.000  1.000

03003380 3    Shallot                           10.000000   1.000  7.500

01033660 1CD  Sweet potato                      10.000000   1.000  1.000

01033661 1CD  Sweet potato-babyfood             10.000000   1.000  1.000

08003750 8    Tomato                             5.000000   1.000  1.000

08003751 8    Tomato-babyfood                    5.000000   1.000  1.000

08003760 8    Tomato, paste                      5.000000   2.000  1.000

08003761 8    Tomato, paste-babyfood             5.000000   2.000  1.000

08003770 8    Tomato, puree                      5.000000   1.200  1.000

08003771 8    Tomato, puree-babyfood             5.000000   1.200  1.000

08003780 8    Tomato, dried                      5.000000  14.300  1.000

08003781 8    Tomato, dried-babyfood             5.000000  14.300  1.000

08003790 8    Tomato, juice                      5.000000   1.500  1.000

86010000 O    Water, direct, all sources         0.001800   1.000  1.000

86020000 O    Water, indirect, all sources       0.001800   1.000  1.000

Tier 1 Chronic Residue Food Plus Ground Water Residue File

Filename: C:\MyFiles\DCNA\DEEMFILES\February2006revisions\031301_c_tier1groundwate r.R98

Chemical: DCNA (Dicloran, Dichloroaniline)

RfD(Chronic): .0025 mg/kg bw/day  NOEL(Chronic): 2.5 mg/kg bw/day

RfD(Acute): .05 mg/kg bw/day  NOEL(Acute):  50 mg/kg bw/day

Date created/last modified: 02-13-2006/14:42:51/8          Program ver. 2.03

Comment: Includes ground water;  Tier 1 Chronic

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------