1 01 10 05 BOARD OF SCIENTIFIC COUNSELORS EXECUTIVE COMMITTEE DRAFT AGENDA January 27 28, 2005 The Key Bridge Marriott 1401 Lee Highway Arlington, VA 22209 Tel.: ( 703) 524 6400 Thursday, January 27, 2005 8: 30 a. m.   9: 30 a. m. Subcommittee Meetings Subcommittee Chairs 9: 00 a. m.  9: 30 a. m. Registration 9: 30 a. m.  9: 45 a. m. Welcome and Introductions Dr. Jim Johnson,  Review of Sept Mtg Minutes Chair, Executive Committee  Overview of Agenda 9: 45 a. m.   9: 55 a. m. BOSC DFO Remarks Lori Kowalski, ORD 9: 55 a. m.  10: 15 a. m. AA/ ORD Remarks TBD 10: 15 a. m.   10: 45 a. m. Risk Assessment Workshop Update Dr. Rogene Henderson, Workshop Chair 10: 45 a. m.   11: 00 a. m. Break 11: 00 a. m.   11: 30 a. m. Coastal Condition Report Dr. James Clark, Lead 11: 30 a. m.  12: 00 noon Subcommittee Reports Subcommittee Chairs  Computational Toxicology Dr. George Daston  Mercury Dr. Herb Windom 12: 00 noon  1: 00 p. m. Lunch 1: 00 p. m.   3: 00 p. m. Program Reviews Subcommittee Chairs  EDCs Dr. Anna Harding  Global Change Dr. Clifford Duke, Vice Chair  Human Health Dr. James Clark, Vice Chair 3: 00 p. m.   3: 30 p. m. Break 3: 30 p. m. 4: 30 p. m. Program Reviews ( Continued) Subcommittee Chairs  Particulate Matter Dr. Rogene Henderson  Drinking Water Dr. Gary Sayler 2  Ecological Dr. Michael Clegg 4: 30 p. m.   5: 00 p. m. BOSC Communications Report Dr. Donna Roa, ORD Public  ORD Update Affairs and Science Communication Director 5: 00 p. m. Adjourn Friday, January 28, 2005 8: 30 a. m.  9: 15 a. m. BOSC Issues Dr. William Farland, Acting Deputy for Science for Research and Development 9: 15 a. m.  9: 45 a. m. National Homeland Security Research Mr. Oba Vincent, National Center Homeland Security Research  Management Plan Center  Communications Plan 9: 45 a. m.   10: 00 a. m. Public Comment 10: 00 a. m.   10: 30 a. m. Break 10: 30 a. m.   11: 00 a. m. SAB Activities Dr. George Lambert, SAB Liaison to the BOSC; Dr. Gary Sayler 11: 00a. m.   12 noon Activities of the National Research Dr. John Holmes, NAS Council Committee on Models in the Regulatory Decision Process 12: 00 noon  1: 00 p. m. Lunch 1: 00 p. m.   1: 30 p. m. Future Discussion/ Future Business Dr. Jim Johnson  Meetings in 2005 Chair, Executive Committee  Nomination Subcommittee Update  Ad Hoc Communication Subcommittee 1: 30 p. m Adjourn


[Federal Register Volume 76, Number 111 (Thursday, June 9, 2011)]
[Notices]
[Pages 33752-33753]
[FR Doc No: 2011-14294]

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ENVIRONMENTAL PROTECTION AGENCY

[EPA-HQ-ORD-2009-0694; FRL-9316-6]

Notice of Availability of the External Review Draft of the
Guidance for Applying Quantitative Data To Develop Data-Derived
Extrapolation Factors for Interspecies and Intraspecies Extrapolation

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of document availability for public comment.

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SUMMARY: The Environmental Protection Agency (EPA) is announcing a 45-
day public comment period for the External Review Draft of ``Guidance
for Applying Quantitative Data to Develop Data-Derived Extrapolation
Factors for Interspecies and Intraspecies Extrapolation.'' EPA is
releasing this draft document solely for the purpose of seeking public
comment prior to external peer review. The document will undergo
independent peer review during an expert peer review meeting, which
will be convened, organized, and conducted by an EPA contractor in
2011. The date of the external peer review meeting will be announced in
a subsequent Federal Register notice. All comments received by the
docket closing date July 25, 2011 will be shared with the external peer
review panel for their consideration. Comments received after the close
of the comment period may be considered by EPA when it finalizes the
document. This document has not been formally disseminated by EPA. This
draft guidance does not represent and should not be construed to
represent EPA policy, viewpoint, or determination. Members of the
public may obtain the draft interim guidance from http://www.regulations.gov; or http://www.epa.gov/raf/DDEF/index.htm or from
Dr. Michael Broder via the contact information below.
    This draft Guidance for Data Derived Extrapolation Factors document
outlines approaches for developing factors for inter- and intra-species
extrapolation based on data describing toxicokinetic and/or
toxicodynamic properties of particular agent(s). The draft document was
developed to provide guidance for EPA staff in evaluating such data
and/or information and to provide information to the regulated
community and other interested parties about deriving and implementing
extrapolation factors derived from data instead of defaults.

DATES: All comments received by the docket closing date July 25, 2011
will be shared with the external peer review panel for their
consideration. Comments received beyond that time may be considered by
EPA when it finalizes the document.

ADDRESSES: Submit your comments, identified by Docket ID No. EPA-HQ-
ORD-2009-0694, by one of the following methods:
     http;//www.regulations.gov: Follow the on-line
instructions for submitting comments.
     E-mail<EMAIL_ADDRESS>     Mail: ORD Docket, Environmental Protection Agency,
Mailcode: 28221T, 1200 Pennsylvania Ave., NW., Washington, DC 20460
     Hand Delivery: EPA Docket Center (EPA/DC), Room 3334, EPA
West Building, 1301 Constitution Avenue, NW., Washington, D.C. 20460,
Attention Docket ID No EPA-HQ-ORD-2009-0694. Deliveries are only
accepted from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding
legal holidays. Special arrangements should be made for deliveries of
boxed information.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2009-0694. EPA's policy is that all comments received will be included
in the public docket without change and may be made available online at
http://www.regulations.gov, including any personal information
provided, unless the comment includes information claimed to be
Confidential Business Information (CBI) or other information whose
disclosure is restricted by statute. Do not submit information that you
consider to be CBI or otherwise protected by statute through http://www.regulations.gov or e-mail. The http://www.regulations.gov Web site
is an ``anonymous access'' system, which means EPA will not know your
identity or contact information unless you provide it in the body of
your comment. If you send an e-mail comment directly to EPA, without
going through http://www.regulations.gov, your e-mail address will be
automatically captured and included as part of the comment that is
placed in the public docket and made available on the Internet. If you
submit an electronic comment, EPA recommends that you include your name
and other contact information in the body of your comment and with any
disk or CD-ROM you submit. If EPA cannot read your comment due to
technical difficulties and cannot contact you for clarification, EPA
may not be able to consider your comment. Electronic files should avoid
the use of special characters, any form of encryption, and be free of
any defects or viruses.
    Docket: All documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other material, such
as copyrighted material, will be publicly available only in hard copy.
Publicly available docket materials are available either electronically
in http://www.regulations.gov or in hard copy at the ORD Docket, EPA/
DC, EPA West, Room 3334, 1301 Constitution Ave., NW., Washington, DC.
The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday
through Friday, excluding legal holidays. The telephone number for the
Public Reading Room is<PHONE_NUMBER>, and the telephone

number for the ORD Docket is<PHONE_NUMBER>.

FOR FURTHER INFORMATION CONTACT: Dr. Michael W. Broder, Office of the
Science Advisor, Mail Code 8105-R, U.S. Environmental Protection
Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone
number:<PHONE_NUMBER>; fax number:<PHONE_NUMBER>, E-mail:
<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION: Key goals for the U.S. EPA include improving
the transparency, objectivity and scientific basis for health risk
assessment. In 2005, a WHO-sponsored effort produced guidance on the
development of Chemical-Specific Adjustment Factors (CSAFs). CSAFs are
intended to replace default uncertainty factor values for inter- and
intraspecies extrapolation in health risk assessment. The U.S. EPA
recognizes differences between the WHO guidance and typical Agency risk
assessment practices, policies and guidance. EPA's Risk Assessment
Forum convened a technical panel that initiated work on developing
draft guidance for use in replacing default values for inter- and
intraspecies uncertainty factors with science-based extrapolation
factors. The draft document has been reviewed by EPA's Risk Assessment
Forum and Science and Technology Policy Council and approved for
external review. In 2010, the document was sent to the National Science
and Technology Council (NSTC) Committee on Environment and Natural
Resources, Toxics and Risk Subcommittee for informal review and
comment. The draft document is now available for public comment.
    The draft document has been structured and developed in accordance
with existing Agency policies on health risk assessment. The draft
document provides guidance for the evaluation of data describing
interspecies differences in chemical disposition (toxicokinetics);
interspecies differences in toxicant-induced response (toxicodynamics);
intraspecies differences in chemical disposition (toxicokinetics); and
intraspecies differences in toxicant-induced response (toxicodynamics).
The document maintains the subdivision of the interspecies and
intraspecies uncertainty factors into toxicokinetic and toxicodynamic
components specified in the U.S. EPA Inhalation Reference Concentration
methodology (U.S. EPA, 1994). EPA will consider all peer review and
public comments in finalizing Guidance for Applying Quantitative Data
to Develop Data-Derived Extrapolation Factors for Interspecies and
Intraspecies Extrapolation.

    Dated: May 26, 2011.
Paul T. Anastas,
EPA Science Advisor.
[FR Doc. 2011-14294 Filed 6-8-11; 8:45 am]
BILLING CODE 6560-50-P


[Federal Register Volume 77, Number 231 (Friday, November 30, 2012)]
[Notices]
[Pages 71461-71462]
[FR Doc No: 2012-28948]

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SECURITIES AND EXCHANGE COMMISSION

Submission for OMB Review; Comment Request

Upon Written Request Copies Available From: Securities and Exchange
Commission, Office of Investor Education and Advocacy, Washington, DC
20549-0213.

Extension: Form ADV-E. OMB Control No. 3235-0361, SEC File No. 270-
318.

    Notice is hereby given that, pursuant to the Paperwork Reduction
Act of 1995 (44 U.S.C. 3501 et seq.), the Securities and Exchange
Commission (the ``Commission'') has submitted to the Office of
Management and Budget (``OMB'') a request for extension of the
previously approved collection of information discussed below.
    Form ADV-E (17 CFR 279.8) is the cover sheet for certificates of
accounting filed pursuant to rule 206(4)-2 under the Investment
Advisers Act of 1940 (17 CFR 275.206(4)-2). The rule further requires
that the public accountant file with the Commission a Form ADV-E and
accompanying statement within four business days of the resignation,
dismissal, removal or other termination of its engagement. The annual
burden is approximately three minutes per respondent.
    The estimate of burden hours set forth above is made solely for the
purposes of the Paperwork Reduction Act and is not derived from a
comprehensive or even representative survey or study of the cost of
Commission rules and forms.
    The information provided on Form ADV-E is mandatory. Responses will
not be kept confidential. An agency may not conduct or sponsor a
collection of information unless it displays a currently valid OMB
control number. No person shall be subject to any penalty for failing
to comply with a collection of information subject to the PRA that does
not display a valid OMB control number.
    The public may view the background documentation for this
information collection at the following Web site www.reginfo.gov.
Please direct general comments regarding the above information to the
following persons: (i) Desk Officer for the Securities and Exchange
Commission, Office of Management and Budget, Room 10102, New Executive
Office Building, Washington, DC 20503 or email to<EMAIL_ADDRESS>and (ii) Thomas Bayer, Director/Chief Information
Officer, Securities and Exchange Commission, c/o Remi Pavlik-Simon,
6432 General Green Way, Alexandria, VA 22312; or send an email

to<EMAIL_ADDRESS>Comments must be submitted to OMB within 30
days of this notice.

    Dated: November 26, 2012.
Kevin M. O'Neill,
Deputy Secretary.
[FR Doc. 2012-28948 Filed 11-29-12; 8:45 am]
BILLING CODE 8011-01-P


[Federal Register Volume 77, Number 141 (Monday, July 23, 2012)]
[Notices]
[Pages 43073-43074]
[FR Doc No: 2012-17886]

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ENVIRONMENTAL PROTECTION AGENCY

[FRL-9703-5]

Proposed CERCLA Section 122(h) Settlement Relating to the Jewett
White Lead Company Superfund Site (``Site''), Located on Staten Island,
Richmond County, NY

AGENCY: Environmental Protection Agency.

ACTION: Notice; request for public comment.

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SUMMARY: In accordance with Section 122(i) of the Comprehensive
Environmental Response, Compensation, and Liability Act of 1980, as
amended (``CERCLA''), notice is hereby given by the U.S. Environmental
Protection Agency (``EPA''), Region 2, of a proposed Administrative
Settlement Agreement (``Agreement'') pursuant to Section 122(h)(1) of
CERCLA, and the inherent settlement authority of the United States with
NL Industries, Inc. (the ``Settling Party''). Settling Party is a
potentially responsible party, pursuant to Section 107(a) of CERCLA,
and thus is potentially liable for response costs incurred or to be
incurred at or in connection with the Jewett White Lead Company
Superfund Site (``Site''), located on Staten Island, Richmond County,
New York. Based upon Settling Party's commitment to provide this
funding to EPA, as set forth in the Agreement, EPA intends to perform
or finance this removal action. Within 10 days after the effective
date, Settling Party agrees to pay to EPA $1,374,000. Thereafter,
Settling Party shall pay an additional $176,000 six months after the
effective date of the Agreement. For thirty (30) days following the
date of publication of this notice, EPA will receive written comments
relating to the proposed Agreement.

SUPPLEMENTARY INFORMATION: In accordance with Section 122(i) of the
Comprehensive Environmental Response, Compensation, and Liability Act
of 1980, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby
given by the U.S. Environmental Protection Agency (``EPA''), Region 2,
of a proposed Administrative Settlement Agreement (``Agreement'')
pursuant to Section 122(h)(1) of CERCLA, 42 U.S.C. 9622(h)(1), and the
inherent settlement authority of the United States with NL Industries,
Inc. (the ``Settling Party''). Settling Party is a potentially
responsible party, pursuant to Section 107(a) of CERCLA, 42 U.S.C.
9607(a), and thus is potentially liable for response costs incurred or
to be incurred at or in connection with the Jewett White Lead Company
Superfund Site (``Site''), located on Staten Island, Richmond County,
New York. The Site includes two parcels of land separated by an active
roadway, one located at 2000-2012 Richmond Terrace, and the other at
2015 Richmond Terrace, in the Port Richmond area of the north shore of
Staten Island, New York. EPA and Settling Party seek through this
proposed Agreement to enable Settling Party to finance the performance
of EPA's documented removal action of excavation and off-site disposal
of contaminated soils at the 2000-2012 Richmond Terrace portion of the
Site. Based upon Settling Party's commitment to provide this funding to
EPA, as set forth in the Agreement, EPA intends to perform or finance
this removal action. Within 10 days after the effective date, Settling
Party agrees to pay to EPA $1,374,000. Thereafter, Settling Party shall
pay an additional $176,000 six months after the effective date of the
Agreement. The proposed Agreement includes a covenant by EPA not to sue
or take administrative action against Settling Party pursuant to
Sections 106 and 107 of CERCLA, 42 U.S.C. 9606 and 9607, with regard to

this specific removal action which EPA intends to perform at the 2000-
2012 Richmond Terrace portion of the Site. For thirty (30) days
following the date of publication of this notice, EPA will receive
written comments relating to the proposed Agreement. EPA will consider
all comments received and may modify or withdraw its consent to the
Agreement if comments received disclose facts or considerations that
indicate that the proposed Agreement is inappropriate, improper, or
inadequate. EPA's response to any comments received will be available
for public inspection at EPA Region 2 offices, 290 Broadway, New York,
New York 10007-1866.

DATES: Comments must be submitted on or before August 22, 2012.

ADDRESSES: The Agreement is available for public inspection at EPA
Region 2 offices at 290 Broadway, New York, New York 10007-1866.
Comments should reference the Jewett White Lead Company Superfund Site
(``Site''), located on Staten Island, Richmond County, New York. Index
No. II-CERCLA-02-2012-2016. To request a copy of the Agreement, please
contact the EPA employee identified below.

FOR FURTHER INFORMATION CONTACT: Henry Guzm[aacute]n, Assistant
Regional Counsel, New York/Caribbean Superfund Branch, Office of
Regional Counsel, U.S. Environmental Protection Agency, 290 Broadway--
17th Floor, New York, New York 10007-1866. Telephone:<PHONE_NUMBER>.

    Dated: July 3, 2012.
Walter E. Mugdan,
Director, Emergency and Remedial Response Division, Region 2.
[FR Doc. 2012-17886 Filed 7-20-12; 8:45 am]
BILLING CODE 6560-50-P