[Federal Register: December 23, 2008 (Volume 73, Number 247)]
[Notices]
[Page 78816]
[DOCID:fr23de08-99]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2008-N-0644]

SEQC--The Sequencing Quality Control Project

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice of solicitation.

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SUMMARY: The Food and Drug Administration (FDA) is soliciting
volunteers to participate in the SEQC (Sequencing Quality Control)
project to objectively assess the technical performance of different
next-generation sequencing technologies in DNA (deoxyribonucleic acid)
and RNA (ribonucleic acid) analyses and to evaluate the advantages and
limitations of various bioinformatics solutions in handling and
analyzing the massive new data sets. The SEQC project is a natural
extension of the MicroArray Quality Control (MAQC) project (http://
www.fda.gov/nctr/science/centers/toxicoinformatics/maqc/) and is being
coordinated by the FDA. This project is open to the public. Vendors of
next-generation sequencing technologies and institutions interested in
the generation, management, analysis, and interpretation of the
resulting sequence data are welcome to participate.

DATES: Requests to participate in the SEQC project at the National
Center for Toxicological Research (NCTR) should be submitted on or
before 4:30 p.m., CST, January 9, 2009, or be postmarked on or before
January 9, 2009.

ADDRESSES: Requests to participate in the SEQC project should be sent
to Leming Shi, National Center for Toxicological Research, Food and
Drug Administration, 3900 NCTR Rd., Jefferson, AR 72079,<PHONE_NUMBER>,
FAX:<PHONE_NUMBER>; e-mail<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION: FDA's Critical Path Initiative (http://
www.fda.gov/oc/initiatives/ criticalpath/) identifies pharmacogenomics
as a key opportunity in advancing medical product development and
personalized medicine. FDA has issued the ``Guidance for Industry:
Pharmacogenomic Data Submissions'' (http://www.fda.gov/cder/guidance/
6400fnl.pdf) to facilitate scientific progress in the field of
pharmacogenomic data integration in drug development and medical
diagnostics.
    Microarrays represent a core technology in pharmacogenomics and
toxicogenomics; however, next-generation sequencing technologies
promise to provide some unique advantages in DNA and RNA analyses and
are expected to be adopted by the pharmaceutical and medical industries
for advancing personalized nutrition and medicine.
    The SEQC project, with broad participation from scientists and
reviewers within FDA and collaborators across the public, academic, and
private sectors, is expected to help prepare FDA for the next wave of
submission of genomic data generated from the next-generation
sequencing technologies.

    Dated: December 17, 2008.
Jeffrey Shuren,
Associate Commissioner for Policy and Planning.
[FR Doc. E8-30410 Filed 12-22-08; 8:45 am]

BILLING CODE 4160-01-S


[Federal Register Volume 83, Number 80 (Wednesday, April 25, 2018)]
[Notices]
[Pages 18068-18070]
[FR Doc No: 2018-08580]

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DEPARTMENT OF HOMELAND SECURITY

Federal Emergency Management Agency

[Docket ID FEMA-2018-0002; Internal Agency Docket No. FEMA-B-1819]

Proposed Flood Hazard Determinations

AGENCY: Federal Emergency Management Agency, DHS.

ACTION: Notice.

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SUMMARY: Comments are requested on proposed flood hazard
determinations, which may include additions or modifications of any
Base Flood Elevation (BFE), base flood depth, Special Flood Hazard Area
(SFHA) boundary or zone designation, or regulatory floodway on the
Flood Insurance Rate Maps (FIRMs), and where applicable, in the
supporting Flood Insurance Study (FIS) reports for the communities
listed in the table below. The purpose of this notice is to seek
general information and comment regarding the preliminary FIRM, and
where applicable, the FIS report that the Federal Emergency Management
Agency (FEMA) has provided to the affected communities. The FIRM and
FIS report are the basis of the floodplain management measures that the
community is required either to adopt or to show evidence of having in
effect in order to qualify or remain qualified for participation in the
National Flood Insurance Program (NFIP). In addition, the FIRM and FIS
report, once effective, will be used by insurance agents and others to
calculate appropriate flood insurance premium rates for new buildings
and the contents of those buildings.

DATES: Comments are to be submitted on or before July 24, 2018.

ADDRESSES: The Preliminary FIRM, and where applicable, the FIS report
for each community are available for inspection at both the online
location https://www.fema.gov/preliminaryfloodhazarddata and the
respective Community Map Repository address listed in the tables below.
Additionally, the current effective FIRM and FIS report for each
community are accessible online through the FEMA Map Service Center at
https://msc.fema.gov for comparison.
    You may submit comments, identified by Docket No. FEMA-B-1819, to
Rick Sacbibit, Chief, Engineering Services Branch, Federal Insurance
and Mitigation Administration, FEMA, 400 C Street SW, Washington, DC
20472,

(202) 646-7659, or (email) [email protected].

FOR FURTHER INFORMATION CONTACT: Rick Sacbibit, Chief, Engineering
Services Branch, Federal Insurance and Mitigation Administration, FEMA,
400 C Street SW, Washington, DC 20472,<PHONE_NUMBER>, or (email)
[email protected]; or visit the FEMA Map Information
eXchange (FMIX) online at https://www.floodmaps.fema.gov/fhm/fmx_main.html.

SUPPLEMENTARY INFORMATION: FEMA proposes to make flood hazard
determinations for each community listed below, in accordance with
section 110 of the Flood Disaster Protection Act of 1973, 42 U.S.C.
4104, and 44 CFR 67.4(a).
    These proposed flood hazard determinations, together with the
floodplain management criteria required by 44 CFR 60.3, are the minimum
that are required. They should not be construed to mean that the
community must change any existing ordinances that are more stringent
in their floodplain management requirements. The community may at any
time enact stricter requirements of its own or pursuant to policies
established by other Federal, State, or regional entities. These flood
hazard determinations are used to meet the floodplain management
requirements of the NFIP and also are used to calculate the appropriate
flood insurance premium rates for new buildings built after the FIRM
and FIS report become effective.
    The communities affected by the flood hazard determinations are
provided in the tables below. Any request for reconsideration of the
revised flood hazard information shown on the Preliminary FIRM and FIS
report that satisfies the data requirements outlined in 44 CFR 67.6(b)
is considered an appeal. Comments unrelated to the flood hazard
determinations also will be considered before the FIRM and FIS report
become effective.
    Use of a Scientific Resolution Panel (SRP) is available to
communities in support of the appeal resolution process. SRPs are
independent panels of experts in hydrology, hydraulics, and other
pertinent sciences established to review conflicting scientific and
technical data and provide recommendations for resolution. Use of the
SRP only may be exercised after FEMA and local communities have been
engaged in a collaborative consultation process for at least 60 days
without a mutually acceptable resolution of an appeal. Additional
information regarding the SRP process can be found online at https://www.floodsrp.org/pdfs/srp_overview.pdf.
    The watersheds and/or communities affected are listed in the tables
below. The Preliminary FIRM, and where applicable, FIS report for each
community are available for inspection at both the online location
https://www.fema.gov/preliminaryfloodhazarddata and the respective
Community Map Repository address listed in the tables. For communities
with multiple ongoing Preliminary studies, the studies can be
identified by the unique project number and Preliminary FIRM date
listed in the tables. Additionally, the current effective FIRM and FIS
report for each community are accessible online through the FEMA Map
Service Center at https://msc.fema.gov for comparison.

(Catalog of Federal Domestic Assistance No. 97.022, ``Flood
Insurance.'')

    Dated: April 3, 2018.
Roy E. Wright,
Deputy Associate Administrator for Insurance and Mitigation, Department
of Homeland Security, Federal Emergency Management Agency.

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                                             Community map repository
               Community                             address
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              Craig County, Oklahoma and Incorporated Areas
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         Project: 11-06-2182S Preliminary Date: October 25, 2017
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City of Vinita.........................  City Hall, 104 East Illinois
                                          Avenue, Vinita, OK 74301.
Town of Big Cabin......................  Craig County Emergency
                                          Management, 915 East Apperson
                                          Road, Vinita, OK 74301.
Town of Bluejacket.....................  Craig County Emergency
                                          Management, 915 East Apperson
                                          Road, Vinita, OK 74301.
Town of Ketchum........................  Craig County Emergency
                                          Management, 915 East Apperson
                                          Road, Vinita, OK 74301.
Town of Welch..........................  Craig County Emergency
                                          Management, 915 East Apperson
                                          Road, Vinita, OK 74301.
Unincorporated Areas of Craig County...  Craig County Emergency
                                          Management, 915 East Apperson
                                          Road, Vinita, OK 74301.
------------------------------------------------------------------------
            Delaware County, Oklahoma and Incorporated Areas
------------------------------------------------------------------------
         Project: 11-06-2182S Preliminary Date: October 25, 2017
------------------------------------------------------------------------
City of Grove..........................  City Hall, 104 West 3rd Street,
                                          Grove, OK 74344.
City of Jay............................  Delaware County Emergency
                                          Management, 1411 South
                                          Broadway Street, Grove, OK
                                          74344.
Town of Bernice........................  Town Hall, 104 East Harry
                                          Street, Bernice, OK 74331.
Unincorporated Areas of Delaware County  Delaware County Emergency
                                          Management, 1411 South
                                          Broadway Street, Grove, OK
                                          74344.
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              Mayes County, Oklahoma and Incorporated Areas
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         Project: 11-06-2182S Preliminary Date: October 25, 2017
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Town of Disney.........................  Town Hall, 322 West Main
                                          Street, Disney, OK 74340.
Town of Grand Lake Towne...............  Mayes County Courthouse, 1
                                          Court Place, Suite 140, Pryor,
                                          OK 74361.
Town of Langley........................  Town Hall, 324 West Osage
                                          Street, Langley, OK 74350.
Unincorporated Areas of Mayes County...  Mayes County Courthouse, 1
                                          Court Place, Suite 140, Pryor,
                                          OK 74361.
------------------------------------------------------------------------

             Ottawa County, Oklahoma and Incorporated Areas
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         Project: 11-06-2182S Preliminary Date: October 25, 2017
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City of Commerce.......................  City Hall, 618 Commerce Street,
                                          Commerce, OK 74339.
City of Miami..........................  Civic Center, 129 5th Avenue
                                          Northwest, Miami, OK 74354.
Town of Afton..........................  Town Hall, 201 Southwest 1st
                                          Street, Afton, OK 74331.
Town of Fairland.......................  City Hall, 28 North Main
                                          Street, Fairland, OK 74343.
Town of North Miami....................  City Hall, 309 Pine Street,
                                          North Miami, OK 74358.
Town of Quapaw.........................  City Hall, 410 Main Street,
                                          Quapaw, OK 74363.
Town of Wyandotte......................  City Hall, 212 South Main
                                          Street, Wyandotte, OK 74370.
Unincorporated Areas of Ottawa County..  Ottawa County Courthouse Annex,
                                          123 East Central Boulevard,
                                          Suite 103, Miami, OK 74354.
Wyandotte Nation.......................  Tribal Administration, 64700
                                          East Highway 60, Wyandotte, OK
                                          74370.
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[FR Doc. 2018-08580 Filed 4-24-18; 8:45 am]
 BILLING CODE 9110-12-P