UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D. C. 20460 OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES May 30, 2002 MEMORANDUM SUBJECT: Carbaryl. List A Reregistration Case 0080. Chemical No. 056801. Revised Product and Residue Chemistry Chapters for the Reregistration Eligibility Decision. DP Barcode: D283328.

FROM: Felecia Fort, Chemist Reregistration Branch 1 Health Effects Division (7509C)

THRU: Whang Phang, Ph. D., Branch Senior Scientist Reregistration Branch 1 Health Effects Division (7509C)

TO: Jeff Dawson, Chemist Health Effects Division( 7509C) and Anthony Britten, Chemical Review Manager Special Review and Reregistration Division (7508C)

Attached are the Revised Product and Residue Chemistry Chapters for the Carbaryl Reregistration Eligibility Decision Document (RED). The chapters were revised to incorporate comments submitted by the registrant. These revisions include changes to the requirements for label amendments, changes to label acceptance dates, and changes to the food/ feed use patterns table. The chapters were also changed to reflect uses that are not being supported by the registrant or have been cancelled.

Product Chemistry Most pertinent data requirements are satisfied for the Aventis 99% T, except that data are required for UV/ visible absorption (OPPTS 830.7050). For the Aventis 97.5% and 80% FIs, and the Drexel 50% FI, additional data are required concerning product identity and composition, discussion of formation of impurities, certified limits, enforcement analytical method, oxidation/ reduction, explodability, storage stability, corrosion characteristics, and density (OPPTS 830.1550, 1670, 1750, 1800, 6314, 6316, 6317, 6320, and 7000). Data requirements for the Drexel and Platte 99% Ts, and AgrEvo 97.5% FI, which are repackaged from EPA registered products, will be satisfied by data for the source products. All product specific product chemistry data are required for the Sureco 80% FI, Amvac 46% FI, and AgrEvo 1% FI. Provided that the registrants submit the data required in the attached data summary tables for the carbaryl MPs, and 2 either certify that the suppliers of beginning materials and the manufacturing processes for the carbaryl MPs have not changed since the last comprehensive product chemistry review or submit complete updated product chemistry data packages, HED has no objections to the reregistration of carbaryl with respect to product chemistry data requirements.

Residue Chemistry The residue chemistry database is essentially complete. The reregistration requirements for plant and livestock metabolism are fulfilled. Acceptable metabolism studies depicting the qualitative nature of the residues in lettuce, radish, soybean, ruminants and poultry have been submitted and evaluated. In addition, adequate magnitude of the residue data are available on the following crops: alfalfa, almond, asparagus, beans (dried and succulent), blueberry, broccoli, cabbage, celery, cherry, citrus fruits, clover, corn (sweet and field), cucurbits (cantaloupes, cucumbers and squash), cranberry, flax, grape, head and leaf lettuce, mustard greens, okra, peanut, peas (dried and succulent), pecan, pepper, pistachio, pome fruits, potato, prickly pear cactus, raspberry, rice, sorghum, soybean, spinach, stone fruits, strawberry, sunflower, sweet potato, tobacco, tomato, and walnut.

The following data gaps remain outstanding.

° A review of the labels and supporting residue data indicate that several label amendments are required. Details are provided in the attached chapter.

° The requirement for acceptable enforcement methods which determine residues of concern in plant and livestock commodities remains outstanding.

° The requirements for storage stability data are not satisfied for purposes of reregistration. Additional data are required depicting the storage stability of carbaryl per se in an oilseed, processed commodities of an oily crop, and a dried fruit stored for up to 10 months.

In addition, the registrant is relying on earlier magnitude of the residue studies that are not supported by the existing storage stability data; therefore, additional storage stability data are required. The required data must reflect storage intervals of 18 months for alfalfa commodities, 15 months for potatoes, 22 months for wheat commodities, and 33 months for rangeland grass. In addition, if the registrant wishes to rely on the previously submitted sugar beet processing study, information pertaining to sample conditions and intervals for the study must be submitted.

° For the purpose of reregistration, the requirements for storage stability data for carbaryl residues in livestock commodities are partially satisfied. Additional information on the storage intervals prior to analysis for metabolite residues in the cattle feeding study is required.

° Separate tolerances on many commodities need to be reassigned concomitant with establishing tolerances for the appropriate crop group and subgroup. The recommended changes are summarized in Table C under "Tolerances Needed Under 40 CFR §180.169( a), crop group/ subgroup tolerances." 3 ° The data submitted are not adequate to support the use of granular (G) formulations of carbaryl on leafy vegetables. Residues of carbaryl found in leaf lettuce were not consistent. Both samples of lettuce from the 10% G treatment had substantially higher residues (37.01 and 47.22 ppm) than one of the samples treated with the FlC (23.25 ppm). Additionally, all residues were significantly above the current tolerance of 10 ppm. and all residue data submitted in support of the tolerance in lettuce (< 8.85 ppm). No explanation for the higher residues was given by the registrant. The registrant may elect to repeat the side by side trial on leaf lettuce again or submit a rationale for the results of the leaf lettuce study.

° Data are required depicting residues of carbaryl in/ on grass forage harvested immediately (0 day) following the last of two applications of carbaryl (WP or FlC) at 1.5 lb ai/ A to pasture. A total of 12 field trials are required in areas throughout the U. S.

° Adequate data are available to reassess the tolerances for residues of carbaryl in/ on dried beans, cowpeas, lentils and peas with pods. These data support the establishment of crop subgroup tolerances for edible podded legume vegetables (6A), and for dried, shelled pea and bean except soybean (6C). However, additional residue data are required if the registrant seeks tolerances for residues in/ on succulent, shelled pea and bean commodities. A total of 12 tests, six tests each on a succulent, shelled cultivar of bean and garden pea, are required to support a tolerance for residues in/ on the succulent, shelled pea and bean crop subgroup (6B). The registrant is referred to OPPTS GLN 860.1500 for the number and distribution of tests required.

° Adequate data are available to reassess the tolerance for wheat forage and straw. However, the Agency now considers wheat hay a significant RAC for feed purposes (OPPTS GLN 860.1000 Table 1.). A full set of 20 field trials as specified in OPPTS GLN 860.1500 are required depicting carbaryl residues in/ on wheat hay. When all the field trials are complete, PHIs and tolerances for hay based on the field trial data should be proposed. Data on wheat hay will be translatable to proso millet hay.

° The registrant intends to support a tolerance for residues of carbaryl in/ on imported pineapples (Aventis personal communication with C. Olinger, 9/ 24/ 98 SMART meeting). Residue data are required depicting residues in/ on pineapples following application of carbaryl at the maximum use rate and minimum PHI. Five trials must be submitted, three from Costa Rica and two from Mexico.

° The registrant does not intend to support carbaryl uses on avocados, barley, maple sap, oats, rye, and sweet sorghum; however, IR 4 has indicated (Correspondence from K. Dorschner, IR 4 Project, 9/ 15/ 94) that they may fulfill the residue data requirements for some of these commodities. These data have not been submitted.

cc: List B Rereg. File RDI: WPhang 11/ 7/ 00, WJHazel 10/ 7 /2000 7509C: FFort: RRB1: CM2: Rm 722H: 703 305 7478: 11/ 03/ 2000 CARBARYL Chemical ID No. 056801; Case 0080 Product Chemistry Chapter of the Reregistration Eligibility Decision (RED) Document O O N H CH 3 CARBARYL REREGISTRATION ELIGIBILITY DECISION:

PRODUCT CHEMISTRY CONSIDERATIONS Chemical ID No. 056801; Case No. 0080 DESCRIPTION OF CHEMICAL Carbaryl [1 naphthyl N methylcarbamate] is a broad spectrum insecticide used for control of various insects on numerous varieties of fruits, nuts, and field and vegetable crops.

Empirical Formula: C12H11NO2 Molecular Weight: 201.2 CAS Registry No.: 63 25 2 Chemical ID No.: 056801 IDENTIFICATION OF ACTIVE INGREDIENT Carbaryl is a white to light tan solid with a melting point of 142 C, vapor pressure of <0.005 mm Hg at 26 C, specific gravity of 1.23 at 20 C, and octanol/ water partition coefficient (Koc) of 217. Carbaryl is soluble in water (40 ppm at 25 C) and in organic solvents including dimethyl formamide ( # 45 g/ 100 mL); acetone, cyclohexanone, and isophorone ( # 25 g/ 100 mL); methylethyl ketone ( # 20 g/ 100 mL); dichloromethane ( # 15 g/ 100 mL); ethanol and ethyl acetate ( # 10 g/ 100 mL); mixed aromatic solvents and xylene ( # 3 g/ 100 mL); and kerosene ( # 1 g/ 100 mL). Carbaryl hydrolyzes rapidly in alkaline solutions.

MANUFACTURING USE PRODUCTS A search of the Reference Files System (REFS) conducted 10/ 25/ 00 identified 10 carbaryl manufacturing use products (MPs) registered under Chemical ID No. 056801; the registered carbaryl MPs are listed below in Table 1. Only the registered MPs listed below are subject to a reregistration eligibility decision.

Table 1. Registered Carbaryl Manufacturing Use Products. 3 Table 2. Product chemistry data requirements specified in the Carbaryl FRSTR.

Product OPPTS 830 Guidelines Outstanding 99% T (EPA Reg. No. 264 324) 830.1600, 1620, 1670, 1700, 1750, 1800, 6313, 7000, 7370, and 7950 97.5% T (EPA Reg. No. 264 325) 830.1670, 1750, 1800, 6314, 6316, 6317, 6320, and 7000 80% FI (EPA Reg. No. 264 328) 830.1670, 1750, 1800, 6314, 6316, 6317, 6320, and 7000 99% T (EPA Reg. No. 19713 75) All Group A and B Guidelines 50% FI (EPA Reg. No. 19713 369) a 830.1670, 1750, 1800, 6314, 6316, 6317, 6320, and 7000 97.5% FI (EPA Reg. No. 4816 270) None; data requirements to be satisfied by the source product.

46% FI (EPA Reg. No. 5481 190) All Group A and B Guidelines.

a Based on data submitted by Aventis.

The current status of the product chemistry data requirements for the carbaryl manufacturing use products is presented in the attached data summary tables. Refer to these tables for a listing of the outstanding product chemistry data requirements.

CONCLUSIONS All pertinent product chemistry data requirements are satisfied for the Aventis 99% T, except that data are required for UV/ visible absorption (OPPTS 830.7050). For the Aventis 97.5% and 80% FIs, and the Drexel 50% FI, additional data are required concerning product identity and composition, discussion of formation of impurities, certified limits, enforcement analytical method, oxidation/ reduction, explodability, storage stability corrosion characteristics, and density (OPPTS 830.1550, 1670, 1750, 1800, 6314, 6316, 6317, 6320, and 7000). Data requirements for the Drexel and Platte 99% Ts, and AgrEvo 97.5% FI, which are repackaged from EPA registered products, will be satisfied by data for the source products. All productspecific product chemistry data are required for the Sureco 80% FI, Amvac 46% FI, and AgrEvo 1% FI. Provided that the registrants submit the data required in the attached data summary tables for the carbaryl MPs, and either certify that the suppliers of beginning materials and the manufacturing processes for the carbaryl MPs have not changed since the last comprehensive product chemistry review or submit complete updated product chemistry data packages, HED has no objections to the reregistration of carbaryl with respect to product chemistry data requirements.

AGENCY MEMORANDA CITED IN THIS DOCUMENT CBRS No( s).: 8724 DP Barcode( s): D169720 Subject: Rhone Poulenc Ag Company: Response to the Carbaryl Reregistration Standard: Residue and Product Chemistry Comments From: R. Perfetti 2 Formulation EPA Reg. No. Registrant 99% T 264 324 Aventis Ag Company (formerly Union Carbide) 97.5% FI a 264 325 80% FI 264 328 99% T b 19713 75 Drexel Chemical Company 50% FI c 19713 369 99% T b 34704 707 Platte Chemical Company Inc.

97.5% FI b 4816 270 AgrEvo Environmental Health (formerly Fairfield American) 1% FI 4816 407 80% FI 769 971 Sureco Inc.

46% FI 5481 190 Amvac Chemical Corporation a Although REFS identifies this product as a technical (T), it is appropriately identified as an formulation intermediate (FI) because it is formulated from a registered technical product. b Repackaged from an EPA registered product; confirmed for the Drexel 99% T (EPA Reg. No. 19713 75) subsequent to the FRSTR. c Transferred from Aventis (EPA Reg. No. 264 327; 7/ 15/ 92).

REGULATORY BACKGROUND The Carbaryl Reregistration Standard dated 6/ 11/ 82 and Guidance Document dated 3/ 30/ 84 required additional generic and product specific product chemistry data for the registered carbaryl MPs. The Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88 reviewed data submitted in response to the Guidance Document and summarized the outstanding data requirements for the reregistration of carbaryl. Additional data requirements listed in the FRSTR are presented in Table 2. The FRSTR did not address the AgrEvo 1% FI (EPA Reg. No. 4816 407), which was registered 3/ 31/ 72; the Platte 99% T (EPA Reg. No. 34704 707) and Sureco 80% FI (EPA Reg. No. 769 971) were registered subsequent to issuance of the FRSTR. 4 To: W. Burnam and L. Rossi Dated: 11/ 1/ 91 MRID( s): 41982601 CBRS No( s).: 10083 DP Barcode( s): D179698 Subject: Rhone Poulenc Ag Company: Response to the Carbaryl Reregistration Standard: Nitrosamine & Stability Considerations. From: K. Dockter To: L. Propst/ J. Edwards Dated: 7/ 14/ 92 MRID( s): 42318501 CBRS No( s).: 11101 DP Barcode( s): D186160 Subject: Response to the Carbaryl Reregistration Standard: Product Chemistry From: R. Perfetti To: L. Rossi and E. Saito Dated: 1/ 29/ 93 MRID( s): None CBRS No( s).: 11201 DP Barcode( s): D186515 Subject: Response to the Carbaryl Reregistration Standard: Product Chemistry. From: R. Perfetti To: L. Rossi and E. Saito Dated: 4/ 21/ 93 MRID( s): 42583901 and 42583902 5 CBRS No( s).: 12225 DP Barcode( s): D193013 Subject: Carbaryl Reregistration: List A Chemical No. 056801; Case No. 0080. Rhone Poulenc Response to the Carbaryl Product Chemistry Data Requirements Regarding Dissociation Constant and pH (Guideline Nos. 63 10 and 63 12). From: F. Toghrol To: L. Rossi/ L. Propst Dated: 1/ 26/ 94 MRID( s): 42832401 CBRS No( s).: 13127 DP Barcode( s): D198578 Subject: Carbaryl. Rhone Poulenc 1/ 4/ 94 Response [62 3 data for EPA Reg. 264 324] to 5/ 13/ 93 Agency Letter [RE: 5/ 3/ 88 FRSTR] Rereg. Case 0080. From: K. Dockter To: J. Loranger Dated: 4/ 29/ 94 MRID( s): 43075801 CBRS No( s).: 15442 DP Barcode( s): D214535 Subject: Carbaryl (056801) Reregistration Case No. 0080, Drexel Request for Product Chemistry Generic Data Exemption (GDE), New Confidential Statement of Formula. From: S. Hummel To: J. Loranger/ L. Propst Dated: 5/ 8/ 95 MRID( s): None 6 PRODUCT CHEMISTRY CITATIONS Bibliographic citations include only MRIDs containing data which fulfill data requirements.

References (cited):

00151776 Union Carbide Agricultural Products Co., Inc. (1984) The Name, Chemical Identity and Composition of the Pesticide Chemical Sevin. Unpublished compilation. 336 p.

41982601 McDaniel, R.; Weiler, D. (1987) Vapor Pressure Determination of Carbaryl: Final Report: Lab Project Number: 40196. Unpublished study prepared by Rhone Poulenc Ag Co. 35 p.

42318501 Siemann, L. (1992) Product Chemistry on Technical Grade Carbaryl in Support of Registration: Analysis for Nitrosoamines and Stability Study: [Interim Report]: Lab Project Number: 6489 F. Unpublished study prepared by Midwest Research Institute. 26 p.

42583901 Helfant, L. (1992) Sevin Brand 99% Technical Carbaryl Insecticide: Product Identity and Composition Series 61: Lab Project Number: AC 92 014: 41330. Unpublished study prepared by Rhone Poulenc Ag Co. 42 p.

42583902 Siemann, L. (1992) Product Chemistry on Technical Grade Carbaryl in Support of Registration Analysis for Nitrosoamines and Stability Study: Lab Project Number: 6489 F. Unpublished study prepared by Midwest Research Institute. 149 p.

42832401 Siemann, L. (1993) Carbaryl Product Chemistry: Lab Project Number: 3424 F. Unpublished study prepared by Midwest Research Institute. 21 p.

43075801 Siemann, L. (1993) Method Validation for Analysis of Carbaryl: Lab Project Number: 3521/ F. Unpublished study prepared by Midwest Research Institute. 127 p. 7 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Aventis Ag Company Product( s): 99% T (EPA Reg No. 264 324)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 00151776, 42583901 3 830.1600 Description of materials used to produce the product Y 00151776, 42583901 3 830.1620 Description of production process Y 00151776, 42583901 3 830.1670 Discussion of formation of impurities Y 00151776, 42583901 3 830.1700 Preliminary analysis Y 00151776, 42318501 4 , 42583902 3 830.1750 Certified limits Y 00151776, 42583901 3 830.1800 Enforcement analytical method Y 00151776, 43075801 5 830.6302 Color Y 00151776 830.6303 Physical state Y 00151776 830.6304 Odor Y 00151776 830.6313 Stability to normal and elevated temperature, metals, and metal ions Y 00151776, 42318501 4 830.6314 Oxidation/ reduction: chemical incompatibility Y 00151776 830.6315 Flammability N/ A 6 830.6316 Explodability Y 00151776 830.6317 Storage stability Y 00151776 830.6319 Miscibility N/ A 6 830.6320 Corrosion characteristics Y 00151776 830.7000 pH Y 42832401 7 830.7050 UV/ visible absorption N 8 830.7100 Viscosity N/ A 6 830.7200 Melting point/ melting range Y 00151776 830.7220 Boiling point/ boiling range N/ A 6 830.7300 Density/ relative density/ bulk density Y 00151776 830.7370 Dissociation constants in water Y 42832401 7 830.7550 Partition coefficient (n octanol/ water), shake flask method Y 00151776 830.7840 Water solubility: column elution method; shake flask method Y 00151776 830.7950 Vapor pressure Y 00151776, 41982601 9 1 Y = Yes; N = No; N/ A = Not Applicable. Aventis indicated (CBRS No. 11101, D186160, 1/ 29/ 93, R. Perfetti) that the alternate formulation for which data were required in the FRSTR is no longer produced.

2 MRID 00151776 was reviewed initially under a HED Memorandum from W. T. Chin dated 9/ 18/ 85 and reevaluated in the Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88; remaining references were reviewed as noted.

3 CBRS No. 11201, D186515, 4/ 21/ 93, R. Perfetti.

4 CBRS No. 10083, D179698, 7/ 14/ 92, K. Dockter.

5 CBRS No. 13127, D198578, 4/ 29/ 94, K. Dockter.

6 Data are not required because the T/ TGAI is a solid at room temperature.

7 CBRS No. 12225, D193013, 1/ 26/ 94, F. Toghrol.

8 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

9 CBRS No. 8724, D169720, 11/ 1/ 91, R. Perfetti. 8 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Aventis Ag Company Product( s): 97.5% FI (EPA Reg. No. 264 325)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 00151776 830.1600 Description of materials used to produce the product Y 00151776 830.1650 Description of formulation process Y 00151776 830.1670 Discussion of formation of impurities N 4 00151776 830.1700 Preliminary analysis N/ A 5 830.1750 Certified limits N 3 00151776 830.1800 Enforcement analytical method N 6 00151776 830.6302 Color Y 00151776 830.6303 Physical state Y 00151776 830.6304 Odor Y 00151776 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 5 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N/ A 7 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 5 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range N/ A 5 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density Y 00151776 830.7370 Dissociation constants in water N/ A 5 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 5 830.7840 Water solubility: column elution method; shake flask method N/ A 5 830.7950 Vapor pressure N/ A 5 1 Y = Yes; N = No; N/ A = Not Applicable. Although REFS identifies this product as a T, it is appropriately identified as an FI because it is formulated from a registered technical product.

2 MRID 00151776 was reviewed initially under a HED Memorandum from W. T. Chin dated 9/ 18/ 85 and reevaluated in the Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88.

3 Product identity, nominal concentrations and proposed certified limits must be submitted on EPA Form 8570 4.

4 A discussion must be submitted concerning the possible formation of impurities associated with the inert ingredients in the MP and the potential for formation of nitrosamines in the formulation process or in storage.

5 Data requirements for the TGAI will be satisfied by data for the technical source product.

6 Supporting validation data must be submitted for the enforcement method used to quantitate the active ingredient in the formulated product.

7 Data are not required because the MP is a solid at room temperature. 9 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Aventis Ag Company Product( s): 80% FI (EPA Reg. No. 264 328)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 00151776 830.1600 Description of materials used to produce the product Y 00151776 830.1650 Description of formulation process Y 00151776 830.1670 Discussion of formation of impurities N 4 00151776 830.1700 Preliminary analysis N/ A 5 830.1750 Certified limits N 3 00151776 830.1800 Enforcement analytical method N 6 00151776 830.6302 Color Y 00151776 830.6303 Physical state Y 00151776 830.6304 Odor Y 00151776 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 5 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N/ A 7 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 5 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range N/ A 5 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density Y 00151776 830.7370 Dissociation constants in water N/ A 5 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 5 830.7840 Water solubility: column elution method; shake flask method N/ A 5 830.7950 Vapor pressure N/ A 5 1 Y = Yes; N = No; N/ A = Not Applicable.

2 MRID 00151776 was reviewed initially under a HED Memorandum from W. T. Chin dated 9/ 18/ 85 and reevaluated in the Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88.

3 Product identity, nominal concentrations and proposed certified limits must be submitted on EPA Form 8570 4.

4 A discussion must be submitted of the possible formation of impurities associated with the inert ingredients in the MP and the potential for formation of nitrosamines in the formulation process or in storage.

5 Data requirements for the TGAI will be satisfied by data for the technical source product.

6 Supporting validation data must be submitted for the enforcement method used to quantitate the active ingredient in the formulated product.

7 Data are not required because the MP is a solid at room temperature. 10 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Drexel Chemical Company Product( s): 99% T (EPA Reg No. 19713 75)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF date not specified CSF dated 8/ 7/ 95 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N/ A 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF (date not specified) reviewed under CBRS No. 15442, D214535, 5/ 8/ 95, S. Hummel, and an updated CSF dated 8/ 7/ 95 (from the product jacket), confirm that this product is repackaged from an EPA registered product; all data requirements will be fulfilled by data for the source product. 11 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Drexel Chemical Company Product( s): 50% FI (EPA Reg. No. 19713 369)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 00151776 830.1600 Description of materials used to produce the product Y 00151776 830.1650 Description of formulation process Y 00151776 830.1670 Discussion of formation of impurities N 4 00151776 830.1700 Preliminary analysis N/ A 5 830.1750 Certified limits N 3 00151776 830.1800 Enforcement analytical method N 6 00151776 830.6302 Color Y 00151776 830.6303 Physical state Y 00151776 830.6304 Odor Y 00151776 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 5 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N/ A 7 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 5 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range N/ A 5 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density Y 00151776 830.7370 Dissociation constants in water N/ A 5 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 5 830.7840 Water solubility: column elution method; shake flask method N/ A 5 830.7950 Vapor pressure N/ A 5 1 Y = Yes; N = No; N/ A = Not Applicable. This product was transferred from Aventis (EPA Reg. No. 264 327); the data summary table includes data submitted by Aventis. Drexel must confirm that the manufacturing process and site have not changed since the product transfer; otherwise, all product chemistry data will be required.

2 MRID 00151776 was reviewed initially under a HED Memorandum from W. T. Chin dated 9/ 18/ 85 and reevaluated in the Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88.

3 Product identity, nominal concentrations and proposed certified limits must be submitted on EPA Form 8570 4.

4 A discussion must be submitted of the possible formation of impurities associated with the inert ingredients in the MP and the potential for formation of nitrosamines in the formulation process or in storage.

5 Data requirements for the TGAI will be satisfied by data for the technical source product.

6 Supporting validation data must be submitted for the enforcement method used to quantitate the active ingredient in the formulated product.

7 Data are not required because the MP is a solid at room temperature. 12 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Platte Chemical Company Product( s): 99% T (EPA Reg No. 34704 707)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF dated 4/ 12/ 91 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N/ A 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF dated 4/ 12/ 91 (from the product jacket) confirms that this product is repackaged from an EPA registered product; all data requirements will be fulfilled by data for the source product. We note that an updated CSF should be submitted reflecting the nominal concentration of the active ingredient in the product. 13 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: AgrEvo Environmental Health Product( s): 97.5% T (EPA Reg No. 4816 270)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF dated 7/ 24/ 91 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N/ A 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF dated 7/ 24/ 91 (from the product jacket) confirms that this product is repackaged from an EPA registered product; all data requirements will be fulfilled by data for the source product. We note that an updated CSF should be submitted reflecting the nominal concentration of the active ingredient in the product. 14 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: AgrEvo Environmental Health Product( s): 1% FI (EPA Reg No. 4816 407)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N CSF dated 7/ 24/ 91 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 3 830.1750 Certified limits N 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 3 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 3 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 3 830.7220 Boiling point/ boiling range N/ A 3 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 3 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 3 830.7840 Water solubility: column elution method; shake flask method N/ A 3 830.7950 Vapor pressure N/ A 3 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF dated 7/ 24/ 91 (from the product jacket) confirms that this product is formulated from an EPA registered product.

3 TGAI data requirements will be satisfied by data for the technical source product. 15 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Sureco Inc. Product( s): 80% FI (EPA Reg No. 769 971)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N CSF dated 9/ 23/ 94 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 3 830.1750 Certified limits N 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 3 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 3 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 3 830.7220 Boiling point/ boiling range N/ A 3 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 3 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 3 830.7840 Water solubility: column elution method; shake flask method N/ A 3 830.7950 Vapor pressure N/ A 3 1 Y = Yes; N = No; N/ A = Not Applicable. A letter from L. Howard, Aventis, to D. Edwards, EPA, dated 9/ 14/ 94 authorizes use of Aventis data to satisfy data requirements for this product; however, until a determination concerning substantial similarity for the two products has been made, all product chemistry data requirements remain outstanding.

2 The CSF available from the product jacket confirms that this product is formulated from an EPA registered product.

3 TGAI data requirements will be satisfied by data for the technical source product. 16 Case No. 0080 Chemical No. 056801 Case Name: Carbaryl Registrant: Amvac Chemical Corporation Product( s): 46% FI (EPA Reg No. 5481 190)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N CSF dated 5/ 18/ 84 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 3 830.1750 Certified limits N 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperature, metals, and metal ions N/ A 3 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ visible absorption N/ A 3 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 3 830.7220 Boiling point/ boiling range N/ A 3 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 3 830.7550 Partition coefficient (n octanol/ water), shake flask method N/ A 3 830.7840 Water solubility: column elution method; shake flask method N/ A 3 830.7950 Vapor pressure N/ A 3 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF dated 5/ 18/ 84 (from the product jacket) confirms that this product is manufactured from an EPAregistered product.

3 TGAI data requirements will be satisfied by data for the technical source product. CARBARYL Chemical ID No. 056801; Case 0080 Residue Chemistry Chapter of the Reregistration Eligibility Decision (RED) Document CARBARYL REREGISTRATION ELIGIBILITY DECISION RESIDUE CHEMISTRY CONSIDERATIONS PC Code 056801; Case 0080 TABLE OF CONTENTS page INTRODUCTION ............................................................. 1 REGULATORY BACKGROUND ................................................ 1 SUMMARY OF SCIENCE FINDINGS ............................................ 2 GLN 860.1300: Nature of the Residue  Plants ................................. 4 GLN 860.1300: Nature of the Residue  Livestock ............................... 5 GLN 860.1340: Residue Analytical Methods ................................... 5 GLN 860.1360: Multiresidue Methods ........................................ 6 GLN 860.1380: Storage Stability Data  Plants ................................. 7 GLN 860.1380: Storage Stability Data  Livestock .............................. 8 GLN 860.1500: Crop Field Trials ............................................ 8 GLN 860.1520: Processed Food/ Feed ....................................... 11 GLN 860.1480: Meat, Milk, Poultry, Eggs .................................... 12 GLN 860.1400: Water, Fish, and Irrigated Crops ............................... 13 GLN 860.1460: Food Handling ............................................ 14 GLNs 860.1850 and 860.1900: Confined/ Field Accumulation in Rotational Crops .... 14 FOOD/ FEED USE PATTERN .................................................. 15 TOLERANCE REASSESSMENT SUMMARY .................................... 78 Tolerances Listed Under 40 CFR §180.169( a), (b), (c), (d), and (e) ................. 80 Tolerance Listed Under 40 CFR §180.319 .................................... 86 Tolerance Listed Under 40 CFR §186.550 .................................... 86 Tolerances Needed Under 40 CFR §180.169( a) ................................ 86 CODEX HARMONIZATION................................................... 89 AGENCY MEMORANDA RELEVANT TO REREGISTRATION ..................... 94 MASTER RECORD IDENTIFICATION NUMBERS................................ 98 O O N H CH 3 CARBARYL REREGISTRATION ELIGIBILITY DECISION RESIDUE CHEMISTRY CONSIDERATIONS PC Code No. 056801; Case 0080 INTRODUCTION Carbaryl (1 naphthyl N methylcarbamate) is a carbamate insecticide registered for use on a variety of field, fruit, and vegetable crops. The reregistration of carbaryl in the United States is being supported by the Aventis Crop Science (basic producer); the Interregional Research Project No. 4 (IR 4) is additionally supporting the reregistration of carbaryl use on a few selected minor crops. Carbaryl products are marketed under trade names such as Sevin® and Sevimol®. Registered carbaryl end use formulations include flowable concentrates (FlC), granulars (G), pelleted/ tableted (P/ T), ready to use (RTU), and wettable powders (WP). Depending on the crop, these formulations may be applied as dormant, delayed dormant, prebloom, foliar (broadcast, banded, and directed spray), post harvest treatment (dip), soil (broadcast and banded), premise treatment, and direct animal treatment using ground or aerial equipment. Carbaryl may be applied on agricultural and residential use sites.

REGULATORY BACKGROUND Carbaryl was the subject of a Reregistration Standard Guidance Document dated 3/ 30/ 84; the Residue Chemistry Science Chapter of the Guidance Document was dated 3/ 15/ 83. The Residue Chemistry Chapter of the Carbaryl (FRSTR) Reregistration Standard was issued on 5/ 3/ 88. A Data Call In (DCI) Notice for carbaryl was also issued 4/ 91. These documents summarized the regulatory conclusions based on available residue chemistry data, and specified the additional data required for reregistration purposes. Several data submissions have been received and evaluated since the FRSTR. The information contained in this document outlines the Residue Chemistry Science Assessments with respect to the reregistration of carbaryl.

Tolerances for residues of carbaryl are currently expressed in terms of carbaryl (1 naphthyl Nmethylcarbamate including its hydrolysis product 1 naphthol, calculated as carbaryl, for most raw crop commodities [40 CFR §180.169( a)]. The established tolerances for residues in/ on pineapples, pome fruits, avocados, and fresh dill are expressed in terms of carbaryl per se [40 CFR §180.169( d) and (e)]. Tolerances for residues in livestock commodities are expressed as 2 carbaryl, including its metabolites 1 naphthol (naphthyl sulfate), 5,6 dihydrodihydroxy carbaryl, and 5,6 dihydrodihydroxy naphthol, calculated as carbaryl [40 CFR §180.169( b) and (c)]. A tolerance for residues in pineapple bran is expressed in terms of carbaryl per se [40 CFR §186.550]. An interim tolerance has been established for carbaryl and its 1 naphthol metabolite in eggs [40 CFR §180.319].

Since the FRSTR was issued, the Agency has updated the list of raw agricultural and processed commodities and feedstuffs derived from crops (Table 1, OPPTS 860.1000). As a result of changes to Table 1, additional carbaryl residue data are now required for some commodities; these data requirements have been incorporated into this document. These new data requirements will be imposed at the issuance of the Carbaryl RED but should not delay on the reregistration eligibility decisions for carbaryl. The need for revisions to dietary exposure/ risk assessments will be determined upon receipt of the required residue chemistry data.

SUMMARY OF SCIENCE FINDINGS GLN 860.1200: Directions for Use A REFS search, conducted on 1/ 5/ 2000, identified 15 carbaryl end use products (EPs) registered under FIFRA Section 3 to the basic producer, Aventis Ag Company, with registered uses on food/ feed crops. These EPs, including the associated Special Local Need (SLN) registrations under FIFRA Section 24 (c), are listed in Table A1. 3 Table A1. Carbaryl EPs with Food/ Feed Uses Registered to Aventis Ag Company.

EPA Reg. No. Label Acceptance Date 1 Formulation Product Name 234 312 6/ 99 10.04% P/ T Sevin® brand 10% Bait Carbaryl Insecticide 264 314 6/ 99 50% WP Sevin® brand 50W Carbaryl Insecticide 264 315 6/ 99 85% WP Sevin® brand 85 Sprayable Carbaryl Insecticide 264 316 2 1/ 00 80% WP Sevin® brand 80S Carbaryl Insecticide 264 320 6/ 99 5% P/ T Sevin® brand 5% Bait Carbaryl Insecticide 264 321 6/ 99 4 lb/ gal FlC Sevimol® brand Carbaryl Insecticide 264 333 2/ 01 4 lb/ gal FlC Sevin® brand XLR Carbaryl Insecticide 264 334 2/ 99 2 lb/ gal FlC Sevin® brand RP2 Carbaryl Insecticide 264 335 10/ 00 4 lb/ gal FlC Sevin® brand RP4 Carbaryl Insecticide 264 349 3 1/ 00 4 lb/ gal FlC Sevin® brand 4F Carbaryl Insecticide 264 422 4/ 97 4 lb/ gal RTU Sevin® brand 4 Oil ULV Carbaryl Insecticide 264 427 9/ 96 3.2 lb/ gal RTU Sevin® brand 4 Oil 41A Carbaryl Insecticide 264 429 3/ 99 7% G Sevin® brand Granular Carbaryl Insecticide For Commercial Use Only 264 430 3/ 99 6 7% G Sevin® brand Granular Carbaryl Insecticide For Outdoor Home Use 264 526 4/ 00 80% WP Sevin® brand 80 WSP Carbaryl Insecticide 1 Date of the most recently EPA approved label submitted by the basic producer which corresponds to the most recently EPA approved label date found in REFs, unless specified otherwise. 2 Including SLN Nos. CA810059, FL890036, and WA900013. 3 Including SLN No. FL890037.

A review of the labels listed above and supporting residue data indicate that the following label amendments are required:

Based on acceptable residue data on okra from IR 4, the registrant should amend use directions on FlC and WP labels to specify a maximum of four applications per season at 1.5 lb ai/ A/ application at a minimum retreatment interval (RTI) of 6 days and a minimum PHI of 3 days.

Use directions for oysters on the 80% WP label (SLN WA900013) concerning the PHI should be amended to read "treatment is allowed only on beds from which no oysters will be harvested within one year of application."

A comprehensive summary of the registered food/ feed use patterns of carbaryl, based on the product labels registered to Aventis, is presented in Table A2. A tabular summary of the residue chemistry science assessments for reregistration of carbaryl is presented in Table B. The conclusions listed in Table B regarding the reregistration eligibility of carbaryl food/ feed uses are based on the use patterns registered by the basic producer, Aventis. When end use product DCIs are developed (e. g., at issuance of the RED), all end use product labels (e. g., MAI labels, SLNs, 4 and products subject to the generic data exemption) should be amended such that they are consistent with the basic producer's labels.

GLN 860.1300: Nature of the Residue  Plants The reregistration requirements for plant metabolism are fulfilled. Acceptable metabolism studies depicting the qualitative nature of the residues in lettuce, radish, and soybean have been submitted and evaluated.

In these studies (all conducted at  1x rates), surface residues on radish tops, lettuce, and soybean forage accounted for 38 67% of the total radioactive residues (TRR), and virtually all of these residues were unconjugated carbaryl. Unconjugated carbaryl ranged from 36 95% of the TRR in all commodities of radish, lettuce, and soybean, with the exception of soybean seed, in which the parent accounted for only 4% of the TRR. Other unconjugated residues, including N( hydroxymethyl) carbaryl (N OH Me carbaryl), 1 naphthol, and 5,6 dihydro dihydroxy 1 naphthol, were present in minor amounts ( # 3.4% of the TRR).

Conjugated carbaryl accounted for # 2.8% of the TRR in the tested commodities. Other conjugates detected in plants included a malonylglycoside conjugate of 1 naphthol comprising 26% of the TRR in soybeans; a hexose conjugate of N OH Me carbaryl accounting for 17% and 12.2% of the TRR in soybeans and soybean hay; and several minor conjugates of desmethyl carbaryl, 5 hydroxycarbaryl, and 4 hydroxycarbaryl, each at # 2.7% of the TRR.

Based on the available metabolism data, the HED Metabolism Committee (S. Hummel, 2/ 8/ 96) determined that tolerances for crop commodities should be expressed as residues of carbaryl per se. The carbaryl metabolite, N hydroxymethyl carbaryl does not need to be regulated because it is expected to have considerably less potential as a cholinesterase inhibitor (based on in vitro studies). As noted above, conjugated carbaryl does not contribute significantly to the TRR, and is not of concern.

GLN 860.1300: Nature of the Residue  Livestock The reregistration requirements for livestock metabolism are fulfilled. Acceptable metabolism studies depicting the qualitative nature of the residues in ruminants and poultry have been submitted and evaluated. The metabolic pathways for carbaryl in plants and livestocks are similar, but are more extensive in livestocks.

In the ruminant metabolism study, lactating cows were orally dosed with 1 naphthyl[ 14 C] carbaryl at dietary levels of 10 100 ppm for 14 days. The high dose group represents approximately a 0.8x feeding level based on current tolerance levels. The Metabolism Assessment Review Committee (6/ 17/ 99) concluded that tolerances for ruminant meat and milk should be expressed as residues of free and conjugated forms of carbaryl, 5,6 dihydro 5,6 dihydroxy carbaryl, and 5 methoxy 6 hydroxy carbaryl. The tolerance expression should be modified to reflect these changes. 5 Currently, no tolerances are needed for residues of carbaryl in/ on poultry; the presently registered uses of carbaryl are classified as Category 3 of 40 CFR §180.6( a) with respect to the need for tolerances in poultry and eggs i. e., there is no reasonable expectation of finite residues.

GLN 860.1340: Residue Analytical Methods The available methods for tolerance enforcement (PAM, Volume II, Methods I through IV, A, and B) measure total combined residues of carbaryl and 1 naphthol, calculated as carbaryl. The requirement for acceptable enforcement methods which determine residues of carbaryl per se in plant and livestock commodities remains outstanding. Athough some analytical methods determine the combined residue of carbaryl and 1 naphthol, it should be noted that 1 napthol is a very minor part of the residue; therefore, the plant commodity tolerances, which are based on carbaryl only, are not greatly exaggerated.

The registrant has proposed as an enforcement method HPLC Method CACR 0194, which quantifies carbaryl per se in plant matrices. This method has undergone successful independent laboratory validation (ILV) using samples of representative plant commodities (oily and non oily matrices), and has also been successfully radiovalidated using samples from plant metabolism studies. The method should be submitted to the Agency for method validation.

Residue data on most crop plants and processed commodities have been collected using the above HPLC method with only minor modifications involving changes in solvents and cleanup procedures. Method CACR 1212, a modification of CACR 0194, has also been used to generate data on residues of carbaryl per se in some of the recent residue studies. The two methods are identical except that with method CACR 1212 residues are extracted with ethyl acetate instead of DCM, and cleanup procedures use deactivated rather than activated Florisil. The carbaryl HPLCalfalfa method, described in the FRSTR, was used to generate data for earlier residue studies. This method does not distinguish between carbaryl and 1 naphthol; however, the Agency concluded (DP Barcode D194407, S. Hummel, 2/ 25/ 94) that the contribution of residues of 1 naphthol is insignificant relative to residues of carbaryl per se.

The registrant must also propose an enforcement method for determining residues of free and conjugated forms of carbaryl, 5,6 dihydro 5,6 dihydroxy carbaryl, and 5 methoxy 6 hydroxy carbaryl in livestock commodities. An adequate HPLC data collection method (Aventis File No. 45186) used to determine residues of carbaryl (free and conjugated) and its metabolites in livestock commodities is available, and has undergone a successful ILV. The method is similar to method CARDC 1286 which was described in a recent Agency review (C. Olinger, 12/ 13/ 99). Once the modified method has been submitted, the Agency will initiate a method validation.

GLN 860.1360: Multiresidue Methods The FDA PESTDATA database indicates that residues of carbaryl per se are completely recovered using FDA Multiresidue Protocols A and D (PAM I Sections 242.2 and 232.4). No data are available concerning the recovery of carbaryl by Protocol E (PAM I Section 211.1 and 211.2). These PAM I methods are not expected to recover conjugated carbaryl residues. 6 GLN 860.1380: Storage Stability Data  Plants The requirements for storage stability data are not satisfied for purposes of reregistration. Additional data are required depicting the storage stability of carbaryl per se in an oilseed, processed commodities of an oily crop, and a dried fruit stored for up to 10 months.

In addition, the registrant is relying on earlier magnitude of the residue studies that are not supported by the existing storage stability data; therefore, additional storage stability data are required. The required data must reflect storage intervals of 18 months for alfalfa commodities, 15 months for potatoes, 22 months for wheat commodities, and 33 months for rangeland grass. In addition, if the registrant wishes to rely on the previously submitted sugar beet processing study, information pertaining to sample conditions and intervals for the study must be submitted.

Adequate storage stability data have been submitted indicating that residues of carbaryl are relatively stable under frozen storage conditions ( 20 C) for up to 12 months in/ on pearled barley and barley flour, head lettuce, potatoes, tomatoes and tomato processed commodities, and wheat forage, hay, and straw. Residue decline was observed in tomato dry pomace after 3 months storage (  30 40%), and barley grain and peanut hulls after 3 months of storage (  50% and 40%, respectively; these commodities are no longer considered to be significant livestock feed items. In a separate study, carbaryl residues were shown to be stable in/ on wheat grain stored at 20 C for up to 7 months.

Adequate storage stability data have been submitted indicating that weathered residues of carbaryl per se are stable at 20 C for at least 15 months in/ on apple fruit, juice, and wet and dry pomace; 13 months in/ on grapes; 12 months in/ on processed raisins; 11 months in/ on almond nutmeat and hulls, and dry bean hay; and 10 months in/ on dry bean vines.

GLN 860.1380: Storage Stability Data  Livestock For the purpose of reregistration, the requirements for storage stability data for carbaryl residues in livestock commodities are partially satisfied. Additional information on the storage intervals prior to analysis for metabolite residues in the cattle feeding study is required. Samples from the feeding study were analyzed for carbaryl per se within the interval of known stability of free carbaryl residues.

The storage stability studies conducted to date indicate that residues of unconjugated carbaryl and metabolites are less stable than conjugated residues. A storage stability study submitted in conjunction with the ruminant feeding study indicated that residues of carbaryl per se are relatively stable in frozen storage for up to 3 months in milk, fat, and muscle and up to 1 month in kidney. Residues of carbaryl per se in liver declined  69% after 2 weeks of storage and continued to decline over the 3 month storage interval (94% decline). Tissue and milk samples from the ruminant feeding study were stored frozen for # 21 days (9 days for liver) prior to carbaryl analysis. The data indicate that conjugated carbaryl related residues are relatively stable in frozen storage for up to 158 days in muscle, 173 days in liver, 196 days in kidney, 215 days in fat, and 7 248 days in milk. A method equivalency study using samples from the feeding study adequately demonstrated that unconjugated residues are not a significant portion of carbaryl residues in liver.

GLN 860.1500: Crop Field Trials Aventis CropScience submitted data to support the use of granular (G) formulations for postemergence applications to several food/ feed crops. HED (DP Barcode D240441, C. Olinger, 1/ 22/ 98) required the registrant to conduct one side by side trial comparing a granular formulation and a spray formulation for each crop group and miscellaneous crop. To these uses, Aventis CropScience submitted data comparing carbaryl residues in/ on asparagus, cabbage, sweet corn, leaf lettuce, black eyed peas, squash, strawberries, tomatoes, and turnips following multiple applications of either a 4 lb/ gal flowable concentrate (FlC) or 10% granular (G) formulation in side by side tests.

A total of nine side by side tests using a 10% G and 4 lb/ gal FlC were conducted on crops representing major field crop groups and miscellaneous commodities (asparagus, cabbage, sweet corn, peas, squash, strawberry, tomato and turnip). The tests were conducted at the maximum label rate specified on the label for the 4 lb/ gal FlC (EPA Reg No. 264 333) and were conducted in a major growing region for each crop.

Carbaryl residues resulting from application of the 10% G formulation were substantially lower than from the FlC formulation in/ on 9 of the 14 commodities analyzed (asparagus, cabbage w/ o wrapper leaves, sweet corn forage, pea hay and dried seeds, squash, strawberries, tomatoes and turnip tops) and were similar in 2 other commodities (sweet corn K+ CWHR and fodder). Although residues of the 10% G formulation were higher than residues from the side by side trial for cabbage (w/ wrapper leaves) and turnip root, the residues were similar or lower than residues found in the residue field trials submitted to the Agency in support of tolerances in/ on turnip and cabbage.

The data submitted are not adequate to support the use of granular (G) formulations of carbaryl on leafy vegetables. Residues of carbaryl found in leaf lettuce were not consistent. Both samples of lettuce from the 10% G treatment had substantially higher residues (37.01 and 47.22 ppm) than one of the samples treated with the FlC (23.25 ppm). Additionally, all residues were significantly above the current tolerance of 10 ppm. and all residue data submitted in support of the tolerance in lettuce (< 8.85 ppm). No explanation for the higher residues was given by the registrant. The registrant may elect to repeat the side by side trial on leaf lettuce again or submit a rationale for the results of the leaf lettuce study.

In addition, conclusions regarding the adequacy of the data for alfalfa, apples, potatoes, wheat processed commodities, grasses, and soybean processed commodities are contingent upon receipt and acceptance of adequate supporting storage stability data.

For the purpose of reregistration, adequate magnitude of the residue data are available on the following crops: alfalfa, almond, asparagus, bananas, beans (dried and succulent), blueberry, broccoli, cabbage, celery, cherry, citrus fruits, clover, corn (sweet and field), cucurbits (cantaloupes, cucumbers and squash), cranberry, flax, grape, okra, peanut, peas (dried and 8 succulent), pecan, pepper, pistachio, pome fruits, potato, prickly pear cactus, raspberry, rice, sorghum, soybean, spinach, stone fruits, strawberry, sunflower, sweet potato, tobacco, tomato, and walnut.

Adequate field trial data depicting carbaryl residues following applications made according to the maximum or proposed use patterns have been submitted for these commodities. Geographic representation is adequate and a sufficient number of trials reflecting representative formulation classes were conducted. Carbaryl residues were <LOQ in/ on sweet potato, sugar beets, corn grain, flax seed, and peanuts. Quantifiable residues were detected in all other RACs. For a given crop, residue levels were quite variable overall, probably owing to climactic variations, but were generally consistent within any specific field trial location.

In addition to the required field trial data, an adequate [ 14 C] carbaryl tobacco pyrolysis study has been conducted.

Adequate data are available to reassess the tolerances for residues of carbaryl in/ on sugar beet roots and tops provided that use directions on five currently approved labels are modified to allow a maximum of two applications per season at 1.5 lb ai/ A/ application and a PHI of 28 days. The registrant has proposed (Letter from Aventis to J. Loranger, 6/ 1/ 94) amending all EP labels to conform to these requirements, and the Greybeard Committee (1/ 9/ 97) has granted a waiver from the requirement of additional field trials provided that the labels are amended. Alternatively, residue data are required depicting residues of carbaryl per se in/ on sugar beet roots and tops harvested 28 days following four applications totaling 4.0 lb ai/ A (1x the maximum seasonal rate). A total of 12 tests should be conducted in the following areas: Region 5 (5 tests), Regions 7, 8, and 9 (one test each), and Regions 10 and 11 (2 tests each).

Adequate residue data on representative Brassica and leafy vegetables are available to support uses on other vegetable commodities with the same carbaryl use pattern: Adequate data on broccoli will be translated to support the uses on Brussels sprouts, cauliflower, and kohlrabi; data on spinach will support tolerances on dandelion and parsley; and residue data on lettuce will be translated to endive.

The available data from alfalfa will be translated to support uses on birdsfoot trefoil.

The following data on grasses are available for risk assessment/ reregistration purposes: Residue data from rangeland grass field trials support the current tolerance of 100 ppm in/ on grass forage. Data on pasture hay harvested at the 14 day PHI indicate that the tolerance on grass hay should be lowered to 15 ppm.

The registrant has provided data on pasture grass forage harvested at a PHI of 14 days. For postemergence applications to grasses, the Agency currently considers feeding restrictions and PHIs greater than zero days impractical for forage of pasture and rangeland grasses. Grass forage tolerances are set using residue data from a 0 day post treatment interval. However, reasonable PHIs are allowed for the cutting of grass hay.

Adequate data are available to reassess the tolerances for residues of carbaryl in/ on dried beans, cowpeas, lentils and peas with pods. These data support the establishment of crop subgroup 9 tolerances for edible podded legume vegetables (6A), and for dried, shelled pea and bean except soybean (6C). However, additional residue data are required if the registrant seeks tolerances for residues in/ on succulent, shelled pea and bean commodities. A total of 12 tests, six tests each on a succulent, shelled cultivar of bean and garden pea, are required to support a tolerance for residues in/ on the succulent, shelled pea and bean crop subgroup (6B). The registrant is referred to OPPTS GLN 860.1500 for the required number and distribution of tests.

Data are available to reassess the tolerances for residues in/ on soybean forage and hay. To establish a tolerance for residues in/ on the foliage of legume vegetables except soybeans crop subgroup (7A), the guidelines state that three field trials each are required on any cultivar of bean and field pea. Although data from forage and hay of field pea are not available, data from seven field trials depicting residues in/ on bean forage (vines) and hay are adequate to satisfy the guidelines for a tolerance on the crop subgroup 7A. The use patterns are the same for forage and hay of peas and beans.

Adequate data are available to reassess the tolerance for wheat forage and straw. However, the Agency now considers wheat hay to be a livestock feed item. (OPPTS GLN 860.1000 Table 1.). A full set of 20 field trials as specified in OPPTS GLN 860.1500 is required depicting carbaryl residues in/ on wheat hay. When all the field trials are complete, PHIs and tolerances for hay based on the field trial data should be proposed. Data on wheat hay will be translatable to proso millet hay.

The registrant intends to support a tolerance for residues of carbaryl in/ on imported pineapples (Aventis personal communication with C. Olinger, 9/ 24/ 98 SMART meeting). Residue data are required depicting residues in/ on pineapples following application of carbaryl at the maximum use rate and minimum PHI. Five trials must be submitted, three from Costa Rica and two from Mexico.

The registrant does not intend to support carbaryl uses on avocados, barley, maple sap, oats, rye, and sweet sorghum; however, IR 4 has indicated (Correspondence from K. Dorschner, IR 4 Project, 9/ 15/ 94) that they may fulfill the residue data requirements for some of these commodities. These data have not been submitted.

GLN 860.1520: Processed Food/ Feed Pending adequate resolution of the outstanding storage stability issues noted above, the reregistration requirements for magnitude of the residue data in processed food/ feed commodities are fulfilled for citrus fruits, corn, flaxseed, grape, olive, peanut, plum, pome fruits, rice, sorghum, soybean, sugar beet, sunflower, potato, tomato, and wheat. Based on the available processing studies, tolerances are required for residues in citrus fruit oil, raisins, wet apple pomace, and rice hulls only.

In a tomato processing study, carbaryl residues concentrated by 2x in puree. However, when this concentration factor is applied the HAFT residues of 2.45 ppm for tomatoes, the resulting value is 10 lower than the reassessed tolerance (5.0 ppm) for residues in/ on fruiting vegetables. Therefore, a separate tolerance for residues in puree is not required.

In an apple processing study, carbaryl residues concentrated in wet apple pomace by 1.3x. Based on this concentration factor and the current HAFT residues of 10.6 ppm in/ on apples, an appropriate tolerance for carbaryl residues in wet apple pomace is 15.0 ppm. Residues did not concentrate in apple juice.

Data from the citrus fruit processing study indicate that residues of carbaryl concentrate in citrus oil by 2.4x. Based on this concentration factor and the current HAFT residues of 8.09 ppm in/ on citrus fruit, an appropriate tolerance for carbaryl residues in citrus oil is 20.0 ppm. Residues did not concentrate in dried pulp or juice.

Data from adequate grape processing studies indicate that residues of carbaryl do not concentrate in grape juice; however, carbaryl residues concentrate by 1.4x in raisins. Based on the current HAFT residues of 7.94 ppm in/ on grapes, carbaryl residues in raisins could be expected to reach 11.1 ppm. A 12.0 ppm tolerance for carbaryl residues in raisins should be established. Residues did not concentrate in dried pulp or juice.

A rice processing study indicated that residues of carbaryl do not concentrate in polished rice or bran, but concentrate in rice hulls by 2.4x. Based on this concentration factor and the current HAFT residues of 11.0 ppm in/ on rice grain, residues in rice hulls could be expected to reach 26.4 ppm; therefore, an appropriate tolerance for carbaryl residues in rice hulls is 30.0 ppm.

Data from a wheat processing study indicate that carbaryl residues in/ on wheat aspirated grain fractions are 11.8x higher than in/ on wheat grain. Based upon HAFT residues of 0.27 ppm, residues of carbaryl may be expected to reach 3.2 ppm in wheat aspirated grain fractions. Adequate soybean aspirated grain fraction data are available and indicate that residues of carbaryl in/ on soybean aspirated grain fractions are 5.6x higher than in soybean seed. Based on HAFT residues of 0.15 ppm, residues of carbaryl may be expected to reach 0.8 ppm in soybean aspirated grain fractions. For grain sorghum, the concentration factor between the aspirated grain fractions and the whole grain samples was 7.4x. Based on HAFT residues of 9.55 ppm, residues of carbaryl could be expected to reach 70.2 ppm in sorghum aspirated grain fractions. As carbaryl residues were nondetectable (< 0.02 ppm) in/ on all samples of field corn grain from field trials conducted at the maximum labeled use rate (8.0 lb ai/ A, MRID 44058001), no carbaryl residue data on aspirated grain fractions derived from field corn grain are required. Based on these data, a tolerance of 70 ppm should be established for residues of carbaryl per se in/ on aspirated grain fractions.

GLN 860.1480: Meat, Milk, Poultry, Eggs The reregistration data requirements for magnitude of the residue in livestock commodities are fulfilled. 11 The presently registered uses of carbaryl are classified as Category 3 of 40 CFR §180.6( a) with respect to the need for tolerances in poultry and eggs i. e., there is no reasonable expectation of finite residues.

Based upon the established or reassessed tolerances for carbaryl residues in/ on livestock feed items, the calculated maximum theoretical dietary burdens for livestock are presented below:

Calculation of maximum dietary burdens of livestock for carbaryl.

Feed Commodity % Dry Matter a % Diet a Tolerance (ppm) b Dietary Contribution (ppm) c Beef and Dairy cattle grass, forage 25 60 100.0 240.00 cowpea seed 88 20 5.0 1. 1 Aspirated grain fraction 85 20 70.0 16.0 TOTAL BURDEN 100 257.1 Swine sorghum grain N/ A 85 10.0 8. 5 cowpea forage N/ A 15 60.0 9. 0 TOTAL BURDEN 100 17.5 a Table 1 (August 1996). b Current or reassessed tolerance from Table C. c Contribution = [tolerance / % DM (if cattle)] X % diet).

An adequate ruminant feeding study is available reflecting the dosing of dairy cattle for 28 days at levels equivalent to 114, 342, and 1140/ 570 ppm in the diet (the high dose level was reduced to 570 ppm on Day 5 due to toxic effects observed in study animals). These dosing levels represent 0.4x, 1.3x, and 4.4/ 2.2x the theoretical dietary burden for cattle, and 6.5x, 19.5x, and 65.1/ 32.6x the theoretical dietary burden for swine. The calculation of the maximum dietary is tentative because data remain outstanding for pasture grass forage.

Based upon the results of this study, tolerances for residues of carbaryl per se in livestock (excluding swine) commodities should be reassessed as follows: 1.0 ppm for milk, 0.5 ppm for fat, 1.0 ppm for meat, and 3.0 ppm for meat byproducts.

Using the results of the feeding study to reassess tolerances for swine, tolerances for residues of carbaryl per se in swine commodities should be reassessed as follows: 0.05 ppm for fat, 0.1 ppm for meat, and 0.5 ppm for meat byproducts.

GLN 860.1400: Water, Fish, and Irrigated Crops Adequate residue data are available to support the use of carbaryl on oyster beds in WA. No residue data are required for catfish or crayfish from the use of carbaryl on rice since this use is prohibited on the carbaryl labels. 12 GLN 860.1460: Food Handling Carbaryl is presently not registered for use in food handling establishments; therefore, no residue chemistry data are required under this guideline topic.

GLNs 860.1850 and 860.1900: Confined/ Field Accumulation in Rotational Crops An adequate confined rotational crop study is available, and no additional rotational crop studies are required. The current label restriction against rotating crops for which carbaryl is not registered is adequate. 13 (continued; footnotes follow)

Table A2. Food/ Feed Use Patterns on EP Labels Subject to Reregistration for Carbaryl (Case 0080). 1 Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 Food/ Feed Crop Uses Alfalfa Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal Fl/ C [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 1 per cutting 1.5 lb/ A per cutting 7 Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 14 (continued; footnotes follow)

Almond, chestnut, filbert, pecan, walnut Foliar, dormant/ delayed dormant Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 5.0 lb/ A 4 15.0 lb/ A 14 A maximum of four applications may be made (including dormant/ delayed dormant applications) with a minimum 7 day retreatment interval. For almonds only, dormant/ delayed dormant applications may be made in combination with dormant oil.

Foliar application Ground 50% WP [CA830007] 80% WP [CA830007] 1.0 lb/ 100 gal NS NS 1 (for nut crops) Use limited to CA for nut crops.

Applications may be made at 7 day retreatment intervals or as needed. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 15 (continued; footnotes follow)

Apricot, cherry, nectarine, peach, plum/ prune Foliar and dormant/ delayed dormant Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 3.0 lb/ A 4.0 lb/ A (CA only)

5.0 lb/ A (dormant/ delayed only) 3 (foliar) and 1 (dormant/ delayed dormant) 14.0 lb/ A 3 (except CA)

1 (CA only) A maximum of three foliar applications and one dormant/ delayed dormant application may be made with a minimum 7 day retreatment interval (14 days in CA). A maximum seasonal rate of 14.0 lb ai/ A (5.0 lb ai/ A during dormant/ delayed dormant period and 9.0 lb ai/ A during production season)

has been established.

Foliar application Ground 50% WP [CA830007] 80% WP [CA830007] 1.0 lb/ 100 gal NS NS 3 Use limited to CA. Applications may be made at 7 day retreatment intervals or as needed. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 16 (continued; footnotes follow)

Asparagus Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 3 6.0 lb/ A 3.0 lb/ A for 5% P/ T only 1 A maximum of three applications may be made prior to harvest or a maximum of five applications may be made per crop with a minimum 3 day retreatment interval.

Postharvest Ground or aerial 2 10.0 lb/ A Not applicable (NA) Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 17 (continued; footnotes follow)

Asparagus (continued) Postharvest (to fern or brush growth)

Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 4.0 lb/ A 5 10.0 lb/ A NA A maximum of five applications may be made per crop (spears and ferns combined) with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 1 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval.

Avocado Foliar application Ground 50% WP [CA830007] 80% WP [CA830007] 1.0 lb/ 100 gal 5 NS 5 Use limited to CA. Applications may be made at 7 day retreatment intervals or as needed. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 18 (continued; footnotes follow)

Bean, cowpea, pea Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 1.5 lb/ A 4 6. 0 lb/ A 3 A maximum of four applications may be made with a minimum 7 day retreatment interval.

Bean, fresh and dried (Phaseolus species including snap, navy, and kidney), cowpea, lentil, pea, fresh and dried (pisum species), soybean Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 4 6. 0 lb/ A 3 (fresh beans) 14 (forage) 21 (dried beans, or hay) A maximum of four applications may be made with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 19 (continued; footnotes follow)

Beet, garden, roots, carrot, horseradish, radish, parsnip, rutabaga, salsify Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 6 6. 0 lb/ A 7 A maximum of six applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 20 (continued; footnotes follow)

Beet, garden, tops Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 2.0 lb/ A 5 6. 0 lb/ A 14 A maximum of five applications may be made with a minimum 7 day retreatment interval.

Beet, sugar Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 2.0 lb/ A 4 4. 0 lb/ A 28 (roots and forage) A maximum of four applications may be made with a minimum 14 day retreatment interval.

50% WP [264 314]

4 lb/ gal FlC [264 321] [264 335] 1.5 lb/ A 4 4.0 lb/ A 3.0 lb/ A (FlC) 28 (roots and forage) A maximum of four applications may be made with a minimum 14 day retreatment interval.

80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 333] [264 349] 1.5 lb/ A 2 4.0 lb/ A 3.0 lb/ A (FlC) 28 (roots and forage) A maximum of two applications may be made with a minimum 14 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 21 (continued; footnotes follow)

Blueberry Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 10.0 lb/ A 7 A maximum of five applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 0.05 lb/ 1,000 sq. ft 4 NS 7 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 22 (continued; footnotes follow)

Broccoli, Brussels sprouts, cabbage, cauliflower, Chinese cabbage, collards, kale, kohlrabi, mustard greens Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 6. 0 lb/ A 3 14 (Chinese Cabbage, collards, kale and mustard greens) A maximum of four applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 3 14 (Chinese Cabbage, collards, kale and mustard greens) Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval.

Brussels sprouts (see broccoli)

Cabbage (see broccoli) Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 23 (continued; footnotes follow)

Caneberry Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 10.0 lb/ A 7 A maximum of five applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval.

Carrot (see beet, garden)

Cauliflower (see broccoli)

Celery, dandelion Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 24 (continued; footnotes follow)

Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 6. 0 lb/ A 14 A maximum of five applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 25 (continued; footnotes follow)

Cherry (see apricot)

Chestnut (see almond)

Chinese cabbage (see broccoli)

Citrus fruits Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 7.5 lb/ A 8 16.0 lb/ A 5 A maximum of eight applications may be made with a minimum 14 day retreatment interval.

16.0 lb/ A 1 16.0 lb/ A 5 Use limited to CA for control of California red scale and yellow scale.

Foliar application Ground 50% WP [CA83007] 80% WP [CA83007] 1.0 lb/ 100 gal NS NS 5 Use limited to CA. Applications may be made at 7 day retreatment intervals or as needed. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 26 (continued; footnotes follow)

Citrus fruits (continued)

Foliar application Ground or aerial 80% WP [FL890036] 4 lb/ gal FlC [FL890037] 10.0 lb/ A NS NS 5 Use limited to FL. Applications may be made as a dilute or concentrate spray using ground equipment or in a minimum of 10 gal/ A by air.

Applications may be made as needed.

Clover Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 1 per cutting 1.5 lb/ A per cutting 7 Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 27 (continued; footnotes follow)

Collards Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 6.0 lb/ A 6.1 lb/ A for the 2 and 4 lb/ gal FlC (EPA Reg.

Nos. 264 334 and 264 335) 14 See "Broccoli."

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 28 (continued; footnotes follow)

Corn, field and pop Broadcast foliar, banded Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 8. 0 lb/ A 14 (forage and silage)

48 (grain and fodder) A maximum of four applications may be made with a minimum 14 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 29 (continued; footnotes follow)

Corn, sweet Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 8 16.0 lb/ A 2 (ears)

14 (forage)

48 (fodder) A maximum of eight applications may be made with a minimum 3 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 2 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 30 (continued; footnotes follow)

Cotton Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 1.5 lb/ A 4 6. 0 lb/ A 14 (forage) 28 (seed) A maximum of four applications may be made with a minimum 7 day retreatment interval.

Band and/ or directed spray Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 4 6. 0 lb/ A 14 (forage) 28 (seed) Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 31 (continued; footnotes follow)

Cowpea (see bean)

Cranberry Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 10.0 lb/ A 7 See "Blueberry." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 32 (continued; footnotes follow)

Cucumber, melon, pumpkin, squash Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.0 lb/ A 6 6. 0 lb/ A 3 A maximum of six applications may be made with a minimum 7 day retreatment interval.

P/ T formulations not used on pumpkins Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 33 (continued; footnotes follow)

Dandelion (see celery)

Eggplant (see tomato)

Endive (see lettuce)

Filbert (see almond)

Flax Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 42 (seed and straw) Use prohibited in CA. A maximum of two applications may be made with a minimum 14 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 34 (continued; footnotes follow)

Grape Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 10.0 lb/ A 7 See "Blueberry."

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 See "Blueberry." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 35 (continued; footnotes follow)

Grasses (grown for seed)

Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 14 A maximum of two applications may be made with a minimum 14 day retreatment interval.

Horseradish (see beet, garden)

Kale (see broccoli) Kohlrabi (see broccoli) Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 36 (continued; footnotes follow)

Lentil (see bean)

Lettuce, head and leaf; endive Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 6. 0 lb/ A 14 See "Beet, garden, top" or "Celery."

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 See "Celery." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 37 (continued; footnotes follow)

Melon (see cucumber)

Millet, proso Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 7 (forage) 21 (grain and straw) A maximum of two applications may be made with a minimum 14 day retreatment interval. Use of the 50%,

80%, and 85% WP (EPA Reg. Nos.

264 314, 264 315, 264 316, and 264

526) and the 4 lb/ gal FlC (EPA Reg.

Nos. 264 321, 264 333, 264 335, and 264 349) formulations is prohibited in CA. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 38 (continued; footnotes follow)

Mustard greens Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 6.0 lb/ A 6.1 lb/ A for the 2 and 4 lb/ gal FlC (EPA Reg.

Nos. 264 334 and 264 335) 14 See "Broccoli."

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 A maximum of four applications may be made per year with a minimum 7

day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 39 (continued; footnotes follow)

Nectarine (see apricot)

Olive Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 7.5 lb/ A 2 15.0 lb/ A 14 A maximum of two applications may be made with a minimum 14 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 40 (continued; footnotes follow)

Parsley (see lettuce)

Parsnip (see beet, garden)

Pastures Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 14 A maximum of two applications may be made with a minimum 14 day retreatment interval.

Cereal grain bait application Ground or aerial 4 lb/ gal FlC [264 333] 0.5 lb/ A 1 NS 0 Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 41 (continued; footnotes follow)

Peach (see apricot)

Peanut Broadcast foliar, banded Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 1.0 lb/ A 5 8. 0 lb/ A 14 A maximum of five applications may be made with a minimum 7 day retreatment interval.

50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 8. 0 lb/ A 14 A maximum of five applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 42 (continued; footnotes follow)

Pea (see bean)

Pea, fresh and dried (Pisum species) and Southern pea (see bean)

Pecan (see almond)

Pepper (see tomato)

Pistachio Dormant/ delayed dormant and foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 5.0 lb/ A 4 15.0 lb/ A 14 A maximum of four applications may be made (including dormant/ delayed dormant applications) with a minimum 7 day retreatment interval.

Dormant/ delayed dormant applications may be made in combination with dormant oil.

Foliar application Aerial 80% WP [CA810059] 6.0 lb/ A 1 NS 14 Use limited to CA. Application may be made in a minimum of 20 gal/ A. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 43 (continued; footnotes follow)

Plum/ Prune (see apricot)

Pome fruits (including apples, pears, loquats, crabapples, oriental pears, and quince)

Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 3.0 lb/ A 8 15.0 lb/ A 3 A maximum of eight applications may be made (including thinning sprays on apples) with a minimum 14 day retreatment interval. Application of the 80% WP (EPA Reg. Nos. 264 316 and 264 526) and 4 lb/ gal FlC (EPA Reg.

Nos. 264 333, 264 335, and 264 349)

formulations to quince are prohibited. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 44 (continued; footnotes follow)

Pome fruits (including apples, pears, loquats, crabapples, oriental pears, and quince)( continued)

Postbloom (for fruit thinning) Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 3.0 lb/ A 8 15.0 lb/ A 3 Use limited to apples. A maximum of eight applications may be made (including thinning sprays on apples)

with a minimum 14 day retreatment interval.

Postbloom (for fruit thinning) Ground 4 lb/ gal FlC [NC960003] [OH960003] [OR950006] [PA960002] [VA950001] [WA940021] 3.0 lb/ A NS 6.0 lb/ A for NC960003 NS Use limited to NC, OH, OR, PA, VA,

and WA. Applications may be made after 80 to 100% petal fall and 9 mm fruit size.

Postbloom (for fruit thinning) Ground 50% WP [NC820007] 1.0 lb/ 100 gal (dilute)

[250 600 gal finished spray/ A] NS NS NS Tank mix use with plant regulator ethephon limited to NC. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 45 (continued; footnotes follow)

Pome fruits (including apples, pears, loquats, crabapples, oriental pears, and quince)( continued)

Foliar application Ground 50% WP [CA83007] 80% WP [CA83007] 1.0 lb/ 100 gal 5 (for loquats) NS 1 (for apples and pears) 5 (for loquats) Use limited to CA. Applications may be made at 7 day retreatment intervals or as needed. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 46 (continued; footnotes follow)

Potato Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 6 6. 0 lb/ A 7 See "Beet, garden, roots." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 47 (continued; footnotes follow)

Potato (continued) Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 See "Beet, garden, roots."

Pumpkin (see cucumber)

Radish (see beet, garden) Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 48 (continued; footnotes follow)

Rangeland Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349]

3.2 lb/ gal RTU [264 427] 3 4 lb/ gal RTU [264 422] 1.0 lb/ A 1 1. 0 lb/ A 0 A maximum of one application may be made per year.

Cereal grain bait application Ground or aerial 4 lb/ gal FlC [264 333]

4 lb/ gal RTU [264 422] 0.5 lb/ A 1 NS 0 Rhubarb Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 49 (continued; footnotes follow)

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 14 See "Celery." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 50 (continued; footnotes follow)

Rice Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 4. 0 lb/ A 14 (grain and straw) A maximum of two applications may be made with a minimum 7 day retreatment interval.

CA only: for control of tadpole shrimp; max number applications and RTI not specified. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 51 (continued; footnotes follow)

Rutabaga (see beet, garden)

Salsify (see beet, garden)

Sorghum, grain Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 6. 0 lb/ A 21 (grain and fodder)

14 (forage and silage) A maximum of four applications may be made with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 52 (continued; footnotes follow)

Soybean (see bean)

Spinach (see lettuce)

Squash (see cucumber) Strawberry Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 5 10.0 lb/ A 7 A maximum of five applications may be made with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 53 (continued; footnotes follow)

Strawberry (continued)

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval.

Sunflower Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 30 (forage) 60 (seed) Use in CA is prohibited. A maximum of two applications may be made with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 54 (continued; footnotes follow)

Sweet potato Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 8 8. 0 lb/ A 7 A maximum of eight applications may be made with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 55 (continued; footnotes follow)

Sweet potato (continued)

Dip treatment Preplant 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 8.0 lb/ 100 gal NS 1. 2 lb/ A NA Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.3 lb/ A 4 NS 7 Use prohibited in CA. A maximum of four applications may be made per year with a minimum 7 day retreatment interval. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 56 (continued; footnotes follow)

Swiss chard (see lettuce)

Tobacco Broadcast foliar (plant bed and field)

Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 4 8. 0 lb/ A 0 A maximum of four applications may be made with a minimum 7 day retreatment interval. Applications may be made in a minimum of 10 gal of finished spray/ A. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 57 (continued; footnotes follow)

Tomato, pepper, eggplant Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

2 lb/ gal FlC [264 334]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 2.0 lb/ A 7 8. 0 lb/ A 3 A maximum of seven applications may be made with a minimum 7 day retreatment interval.

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 3 Use prohibited in CA. A maximum of 4 applications may be made per year with a minimum 7 day RTI. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 58 (continued; footnotes follow)

Trefoil, birdsfoot Broadcast foliar Ground or aerial 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 1 per cutting 1.5 lb/ A per cutting 7 Turnip, roots Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 2.0 lb/ A 6 6. 0 lb/ A 7 See "Beet, garden, roots."

Soil broadcast Before, during, or after the growing season Ground 7% G [264 429] [264 430] 2.2 lb/ A 4 NS 7 See "Beet, garden, root." Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 59 (continued; footnotes follow)

Turnip, tops Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 2.0 lb/ A 5 6. 0 lb/ A 14 See "Beet, garden, top."

Walnut (see almond)

Wheat Broadcast foliar Ground or aerial 5% P/ T [264 320]

10.04% P/ T [264 312] 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 1.5 lb/ A 2 3. 0 lb/ A 7 (forage) 21 (grain and straw) A maximum of two applications may be made with a minimum 14 day retreatment interval. Use of the 50%,

80%, and 85% WP (EPA Reg. Nos.

264 314, 264 315, 264 316, and 264

526) and 4 lb/ gal FlC (EPA Reg. Nos.

264 321, 264 333, 264 335, and 264

349) formulations is prohibited in CA. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 60 (continued; footnotes follow)

Livestock Uses Poultry treatment (chickens, ducks, geese, game birds, pigeons, and turkeys)

Direct animal treatment Electric fog machine 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 349] 5 oz/ 1 gal [1. 5 gal finished spray per 1,000 hens] NS NS 7 day pre

slaughter interval Applications may be repeated in 4 weeks if necessary.

Direct animal treatment Compressed air sprayer 50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 333] [264 335] [264 349] 3.2 oz/ 5 gal [1 gal finished spray per 100 hens] NS NS 7 day pre

slaughter interval Applications may be repeated in 4 weeks if necessary. Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 61 (continued; footnotes follow)

Poultry houses (chickens, ducks, geese, gamebirds, pigeons, and turkeys)

Premise treatment Spreader or sprayer 5% P/ T [264 320]

10.04% P/ T [264 312] 2.4 oz/ 1,000 sq. ft NS NS NA Applications may be made uniformly to the floor or litter area. A 7 day preslaughter interval (PSI) has been established for poultry, game birds and their premises.

50% WP [264 314] 80% WP [264 316] [264 526] 85% WP [264 315]

4 lb/ gal FlC [264 321] [264 335] [246 349] 4 50 lb/ 100 gal [1 2 gal of spray mixture per 1,000 sq.

ft] NS NS NA Applications may be made to the wall,

litter, or roost area. A 7 day PSI has been established for birds and their premises.

Premise treatment Sprayer or duster 80% WP [264 316] [264 526] 1.0 lb/ 1,000 sq. ft NS NS NA Applications may be made as a dilute spray or as a dry dust to floor surface,

walls, cracks, posts, and crevices. A 7

day PSI has been established for birds and their premises.

4 lb/ gal FlC [264 333] [264 335] [264 349] 0.54 0.55 lb/ 1,000 sq.

ft NS NS NA Site Application Type Application Timing Application Equipment Formulation [EPA Reg. No.] Maximum Single Application Rate, ai Maximum Number of Applications Per Season Maximum Seasonal Rate,

ai Preharvest Interval, Days Use Directions and Limitations 2 62 Fish and Shellfish Uses Oyster beds Application to dewatered oyster beds Ground or aerial 80% WP [WA900013] 10.0 lb/ A NS NS 365 Application is for control of ghost shrimp and mud shrimp. Application must be made and completed within 30 minutes after low tide to prevent direct contamination of water. Use is limited to areas greater than 200 feet from channels and sloughs. For aerial application, a 200 foot buffer zone is required between the treatment area and the nearest shellfish to be harvested. A 50 foot buffer zone is required if treatment is by hand spray.

Treatment is allowed only on ground with no oysters within one year of harvest are present.

1 The following labels list a drench spot application to fire ant mounds in rangeland or pastures: Epa Reg. Nos. 264 314, 315, 316, 321, 349, and 526. EPA Reg. Nos.

264 334 and 335 permit drench spot treatment for fire ants on all labeled crops/ sites. The labeled rate for fire ant spot treatment is 6.7 10.6 g/ gal. Granular spot treatment with EPA Reg. Nos. 264 429 and 430 may also be made at 6g/ ant mound.

2 A restriction against planting rotational food and feed crops not listed on the label or other carbaryl labels in carbaryl treated soil is specified on the labels for the following products: EPA Reg. Nos. 264 312, 264 314, 264 315, 264 316, 264 320, 264 321, 264 333, 264 334, 264 335, 264 349, 264 422, 264 427, 264 429, and 264 526.

Irrigation restrictions: (i) Use in irrigation systems prohibited for EPA Reg. No. 264 422, 427; (ii) use of reclaimed irrigation water on upland crops for which no carbaryl tolerances established prohibited for EPA Reg. Nos. 264 312, 314, 315, 320, 321, 333, 334, 335, 349, 422, 427; (iii) may be applied through sprinkler irrigation systems including center pivot and solid set  use of all other types prohibited EPA Reg. Nos. 264 312, 314, 315, 316, 321, 333, 349, 526).

12 Hour RTI for EPA Reg. Nos. 264 312, 314, 315, 316, 320, 321, 333, 335, 349, 422, 427, 526).

3 The 3.2 lb/ gal RTU (EPA Reg. No. 264 427) product label lists the application rates in quarts of product per acre for non cropland and rangeland; however, to make this product label consistent with the other products the application rates should be expressed as fluid ounces per acre. (continued; footnotes follow) 63 Table B. Residue Chemistry Science Assessments for Reregistration of Carbaryl.

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 860.1200: Directions for Use N/ A = Not Applicable Yes 3 860.1300: Plant Metabolism N/ A No 00049135 00053897 00116083 00118342 00124353 00124968 00125170 43249101 4 43249102 4 43249103 4 860.1300: Livestock Metabolism N/ A No 5 00015669 00053897 00080417 00080679 00080680 00080681 00080682 00080683 00080686 00080689 00080690 00091952 00095927 00118346 00118347 00118365 00118368 00118371 00118375 00118376 00118377 00139664 43324601 6,7 860.1340: Residue Analytical Methods Plant commodities N/ A Yes 8 00080417 00080680 00098504 00107017 00118342 00118346 00118366 00118367 00118368 00118370 00118372 00118373 00118377 00124334 00124361 00145884 00147760 00154626 00156736 00159326 05001852 05004154 05004934 05008728 05010424 05014156 05014889 05016141 05018884 05019959 40255702 40408601 43672701 9 43672702 9 43786805 10 44155401 11 Livestock commodities N/ A Yes 12 00061103 00080417 00080680 00118346 00118366 00118367 00118368 00118370 00118372 00118373 00118375 00118376 05001852 05004154 05008728 05010424 05014156 05014889 05016141 05018884 05019959 44286901 13 44286902 13 44286903 13 860.1360: Multiresidue Methods N/ A No 860.1380: Storage Stability Data Plant commodities N/ A Yes 14 00163007 00163009 00163014 40408601 43850902 15 44068401 16 44123101 17 44250301 16 44412501 18 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 64 Livestock commodities N/ A No 44250901 13 44381901 13 860.1500: Crop Field Trials Root and Tuber Vegetables Group Beet, garden, roots 5 [§ 180.169( a)] No 00089868 43813601 10 Beet, sugar, roots None established No 00089868 00163007 40376001 19 40376002 20 Carrot 10 [§ 180.169( a)] No 00090325 43813601 10 Horseradish 5 [§ 180.169( a)] No 00089868 43813601 10 Parsnips 5 [§ 180.169( a)] No 00089868 43813601 10 Potato 0. 2 [§ 180.169( a)] No 00107017 00134421 40512501 20 Radishes 5 [§ 180.169( a)] No 00089868 43813601 10 Salsify, roots 5 [§ 180.169( a)] No 00089868 43813601 10 Turnip, roots 5 [§ 180.169( a)] No 00089868 43813601 10 Sweet potato 0.2 [§ 180.169( a)] No 00107017 43702002 21 Leaves of Root and Tuber Vegetables Group Beet, garden, tops 12 [§ 180.169( a)] No 00089868 43813601 10 Beet, sugar, tops 100 [§ 180.169( a)] No 19 00089868 Salsify, tops 10 [§ 180.169( a)] No 00089868 43813601 10 Turnip, tops 12 [§ 180.169( a)] No 00089868 43813601 10 Leafy Vegetables (except Brassica) Vegetables Group Celery 10 [§ 180.169( a)] No 00124337 43677401 22 Dandelions 12 [§ 180.169( a)] No 22 00089868 43677401 22 Endive 10 [§ 180.169( a)] No 23 00089868 43677401 22 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 65 Lettuce 10 [§ 180.169( a)] No 00089868 00090162 43677401 22 Parsley 12 [§ 180.169( a)] No 23 00089868 43677401 22 Spinach 12 [§ 180.169( a)] No 00089868 43677401 22,24 Swiss chard 12 [§ 180.169( a)] No 00089868 43677401 22 Brassica (Cole) Vegetables Group Broccoli 10 [§ 180.169( a)] No 00090325 43721001 22 44019701 25 Brussels sprouts 10 [§ 180.169( a)] No 26 00090325 43721001 22 Cabbage 10 [§ 180.169( a)] No 00090325 43786806 10  Cauliflower 10 [§ 180.169( a)] No 27 00090325 43721001 22  Chinese cabbage 10 [§ 180.169( a)] No 00089868 43794903 10  Collards 12 [§ 180.169( a)] No 00089868 43794903 10 Kale 12 [§ 180.169( a)] No 00089868 43794903 10  Kohlrabi 10 [§ 180.169( a)] No 27 00090325 43721001 22 Mustard greens 12 [§ 180.169( a)] No 00089868 43794903 10 Legume Vegetables Group Bean, fresh and dried 10 [§ 180.169( a)] No 00089679 00089680 00089681 00082424 00089837 00090113 00163014 00124334 43786804 10 43984701 27 Cowpeas 5 [§ 180.169( a)] No 00089837 43694103 22 Lentils 10 [§ 180.169( a)] No 00089837 00124334 43694103 22 Peas (with pods) 10 [§ 180.169( a)] No 00090113 00124334 43703102 22 Soybeans 5 [§ 180.169( a)] No 00089837 43694102 22 Foliage of Legume Vegetables Group Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 66 Bean, forage and hay 100, forage 100, hay [§ 180.169( a)] No 28 00082424 00089679 00089680 00089681 00089837 00125090 Cowpea, forage and hay 100, forage 100, hay [§ 180.169( a)] No 00089837 43786804 10 Pea, vines 100 [§ 180.169( a)] No 00089837 00124334 43786804 10 Soybean, forage and hay 100, forage 100, hay [§ 180.169( a)] No 00089837 43694102 22 Fruiting Vegetables (Except Cucurbits) Group Eggplant 10 [§ 180.169( a)] No 00089600 43686701 22 43996101 28 Pepper 10 [§ 180.169( a)] No 00089600 43686701 22 Tomato 10 [§ 180.169( a)] No 00089600 00159326 43996101 28 Cucurbit Vegetables Group Cucumber 10 [§ 180.169( a)] No 00089376 43786802 10 Melon 10 [§ 180.169( a)] No 00090325 43786802 10 Pumpkin 10 [§ 180.169( a)] No 00090325 43786802 10 Squash, summer 10 [§ 180.169( a)] No 00089376 43786802 10 Squash, winter 10 [§ 180.169( a)] No 00090325 43786802 10 Citrus Fruits Group Citrus 10 [§ 180.169( a)] No 00090204 00090320 00163008 43802101 15 44211801 29 Pome Fruits Group Pome fruits 10 [§ 180.169( d)] No 00080419 00082420 00082423 00083311 00083312 00089455 00089679 00089680 00159327 44072901 11 Stone Fruits Group Apricot 10 [§ 180.169( a)] No 00090160 43793202 15 44284701 30 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 67 Cherry 10 [§ 180.169( a)] No 00089348 00124345 43793202 15 44284701 30 Nectarine 10 [§ 180.169( a)] No 00090160 43793202 15 44284701 30 Peach 10 [§ 180.169( a)] No 00082422 43793202 15 44284701 30 Plum (fresh prune) 10 [§ 180.169( a)] No 00089348 00124345 43793202 15 44284701 30 Berries Group Blackberry 12 [§ 180.169( a)] No 00089868 43698201 22 Blueberry 10 [§ 180.169( a)] No 00090161 43694101 22 Boysenberry 12 [§ 180.169( a)] No 00089868 43698201 22 Dewberry 12 [§ 180.169( a)] No 00089868 43698201 22 Loganberry 12 [§ 180.169( a)] No 00089868 43698201 22 Raspberry 12 [§ 180.169( a)] No 00089868 43698201 22 Tree Nuts Group Almond, nutmeat and hulls 1, almonds; 40, almonds, hulls [§ 180.169( a)] No 00108985 00140447 43786801 15 Chestnut 1 [§ 180.169( a)] No 43786801 15 43802102 15 Filbert 1 [§ 180.169( a)] No 00090156 43786801 15 43802102 15 Pecan 1 [§ 180.169( a)] No 00123219 43802102 15 Walnut 1 [§ 180.169( a)] No 00108985 00140447 43818901 15 Cereal Grains Group Barley, grain 0 [§ 180.169( a)] No 30 Corn, field and pop 5, fresh (including sweet) K+ CWHR [§ 180.169( a)] No 00089420 00125090 00125107 00163009 44058001 16 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 68 Corn, sweet 5, fresh (including sweet) K+ CWHR [§ 180.169( a)] No 00089378 00089420 00125090 00125107 44058101 11 Millet, proso, grain 3 [§ 180.169( a)] No 31 00074368 43975601 15 Oats, grain 0 [§ 180.169( a)] No 30 Rice, grain 5 [§ 180.169( a)] No 00089837 00125138 43802103 15 Rye, grain 0 [§ 180.169( a)] No 30 Sorghum, grain 10 [§ 180.169( a)] No 43794901 10 Wheat, grain 3 [§ 180.169( a)] No 00015669 00115284 00136415 41594301 32 43975601 15 Forage, Fodder, and Straw of Cereal Grains Group Barley, forage and straw 100, green fodder 100, straw [§ 180.169( a)] No 30 Corn, fodder and forage 100, fodder 100, forage [§ 180.169( a)] No 00089378 00089420 00125090 00125107 44058001 33 44058101 11 Millet, proso, straw 100 [§ 180.169( a)] No 31 00074368 43975601 15 Oats, forage and straw 100, green fodder 100, straw [§ 180.169( a)] No 30 Rice, straw 100, straw [§ 180.169( a)] No 00089837 00125138 43802103 15 Rye, forage 100, green fodder 100, straw [§ 180.169( a)] No 30 Sorghum, forage 100, forage [§ 180.169( a)] No 00159329 43794901 10 Wheat, forage and straw 100, green fodder 100, straw [§ 180.169( a)] Yes 34 00015669 00115284 00136415 Grass Forage, Fodder, and Hay Group Pastures 100, grass; 100, hay [§ 180.169( a)] Yes 35 00089837 00125121 00125123 00125555 00163006 43716601 22 Rangeland 100, grass; 100, hay [§ 180.169( a)] No 00089837 00125121 00125123 00125555 00163006 44065901 34 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 69 Non grass Livestock Feeds (Forage, Fodder, Straw, and Hay) Group Alfalfa, forage and hay 100, fresh; 100, hay [§ 180.169( a)] No 00089837 00125121 00125123 00159325 Birdsfoot trefoil, forage and hay 100, fresh; 100, hay [§ 180.169( a)] No 00089837 00125121 00125123 00159325 Clover, forage and hay 100, fresh; 100, hay [§ 180.169( a)] No 00089837 00125121 00125123 43694105 22 Herbs and Spices Group Dill, fresh 0.2 [§ 180.169( e)] No PP# 7E3543 36 Miscellaneous Commodities Aspirated grain fractions None No 37 43794902 10 43813602 10 Asparagus 10 [§ 180.169( a)] No 00083527 00140449 43654201 10 Avocado 10 [§ 180.169( e)] No 30 Banana 10 [§ 180.169( a)] No 44798401 39 Cranberry 10 [§ 180.169( a)] No 00090161 43697604 22 Cotton, seed and forage 5, cottonseed 100, cotton forage [§ 180.169( a)] No (Revoke) 38 00089837 00124343 00125099 40881307 Flax, seed and straw 5, seed; 100, straw [§ 180.169( a)] No 00074366 00074367 43982801 15 Grapes 10 [§ 180.169( a)] No 00089418 00089458 00125084 43793201 15 Maple, sap 0.5 [§ 180.169( a)] No 30 Okra 10 [§ 180.169( a)] No 00090229 44123101 17 Olives 10 [§ 180.169( a)] No 40 00090281 43702001 22 44321301 18 Peanuts, nut and hay 5, peanut; 100, hay [§ 180.169( a)] No 00089837 43703101 22 Pineapple 2. 0 [§ 180.169( d)] Yes 39 PP# 5F3208 Pistachio nuts 1 [§ 180.169( a)] No 00124335 43703103 22 Prickly pear cactus 12, fruit; 12, pads [§ 180.169( a)] No 00103288 44145201 17 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 70 Strawberry 10 [§ 180.169( a)] No 00089348 43698202 22 Sunflower 1, seeds [§ 180.169( a)] No 00058927 00058928 43786803 10 Tobacco None established No 44114301 40 860.1520: Processed Food/ Feed Beet, sugar None established No 00163017 Citrus fruits None established No 43694104 22 Corn, field None established No 00163018 43915201 15 Cottonseed None established No 43850901 15 Flaxseed None established No 00074366 00074367 Grapes None established No 00163010 00163011 43697601 22 43697602 22 Olives None established No 43698203 22 Peanut None established No 00163012 44046101 26 Pineapple 20, bran [§ 186.550] No PP# 5F3208 41 Plum None established No 00159328 Pome fruits None established No 43702003 22 Potato None established No 00159324 43697603 22 Rice None established No 00163013 43813603 10 Sorghum None established No 00163015 43813604 10 Soybean None established No 00163016 43794902 10 Sunflower None established No 43845205 15 Tomato None established No 43686702 22 Wheat None established No 43813602 10 860.1480: Meat, Milk, Poultry, Eggs Milk and the Fat, Meat, and Meat Byproducts of Cattle, Goats, Hogs, Horses, and Sheep 0.1, fat, meat, and meat byproducts; 1, kidney and liver [§ 180.169( b)] No 00015669 00061106 00080417 00080419 00080420 00089380 00089836 00089837 00118342 00118346 00118367 00118368 00118370 00118372 00118373 00118374 00118378 40881302 40881312 40881313 40881314 44250901 13 44381901 13 Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 (continued; footnotes follow) 71 Fat, Meat, and Meat Byproducts of Poultry 5.0 Fat and meat [§ 180.169( b)] No 00061103 00080420 00080680 00118375 00118376 00124367 00125571 00135678 00135680 40881308 40881309 Eggs 0.5 [§ 180.319] No Table B (continued).

GLN: Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? 1 References 2 72 1. Reassessed tolerances for leafy vegetables remain tentative until granular data required to support the reregistration of carbaryl are submitted. The registrant should conduct one side by side trial comparing a granular formulation and a spray formulation. If the residues resulting from use of the granular formulation for all crops are the same or less than the spray formulation, then no additional granular data would be required.

2. Bolded references were reviewed in the Residue Chemistry Chapter of the Carbaryl Reregistration Standard dated 3/ 15/ 83 or the Interim Residue Chemistry Chapter of the Carbaryl Reregistration Standard dated 3/ 30/ 84. Italicized references were reviewed in the Residue Chemistry Chapter of the Carbaryl (FRSTR) Reregistration Standard dated 5/ 3/ 88. All other references were reviewed as noted.

3. Label revisions are required for several crops in order to reflect the parameters of use patterns for which residue data are available. Details of the required label amendments are presented in the Directions for Use section.

4. DP Barcode D204197, 11/ 28/ 95, S. Hummel.

5. No tolerances are needed for residues of carbaryl in/ on poultry; the presently registered uses of carbaryl are classified as Category 3 of 40 CFR §180.6( a) with respect to the need for tolerances in poultry and eggs i. e., there is no reasonable expectation of finite residues.

6. CB No. 14249, DP Barcode D206777, 11/ 28/ 95, S. Hummel.

7. DP Barcode D255855, C. Olinger, 5/ 16/ 99 and 6/ 17/ 99.

8. The proposed HPLC enforcement method for carbaryl per se in plants (Method CACR 0194) should be submitted to the Agency for validation.

9. DP Barcode D216544, S. Hummel, 1/ 22/ 96.