PAGE INTENTIONALLY LEFT BLANK William C. Herz Director of Scientific Programs M E M O R A N D U M TO: Product Testing Recipient FROM: William C. Herz, Director, Scientific Programs SUBJECT: Potassium Sulfate Product Testing Dossier DATE: March 15, 2003 It is with great pleasure that The Fertilizer Institute ( TFI) announces the completion and distribution of the final product testing dossier for Potassium Sulfate ( CAS # 7778 80 5).

As you are aware, TFI sponsored this four   year program to develop and summarize screeninglevel hazard information for high production volume ( HPV) chemicals. The data elements generated represent a broad overview of human health and ecological parameters. These include a physical  chemical characterization, environmental fate, mammalian toxicity and ecotoxicity. A health and environmental safety data summary dossier was prepared for each of the 23 materials. It summarizes the available literature data, new testing data, category description and read across data as well as provides a conclusion regarding the inherent hazards of the material.

Upon receipt of this data a 90 calendar day regulatory trigger starts within which you must update your material safety data sheets ( MS DS). Upon first product shipment you must also notify your distributors and employers once the MS DS has been updated. These regulatory requirements are detailed in 29 CFR 1910.1200( g)( 5) and 29 CFR 1910.1200( g)( 6)( i). The requirements are found in the Occupational Safety and Health Administration " Hazard Communication Standard" ( 29 CFR 1910.1200).

Please note that by receipt of this data; you agree not to distribute or sell this data beyond your own company. PAGE INTENTIONALLY LEFT BLANK HEALTH & ENVIRONMENTAL SAFETY DATA SUMMARY DOCUMENT POTASSIUM SULFATE CAS NO. 7778 80 5 Prepared for:

THE FERTILIZER INSTITUTE January 27, 2003 THE WEINBERG GROUP INC. 1220 Nineteenth St, NW, Suite 300 Washington, DC 20036 2400 e mail science@ weinberggroup. com WASHINGTON NEW YORK SAN FRANCISCO BRUSSELS PARIS PAGE INTENTIONALLY LEFT BLANK TABLE OF CONTENTS Page EXECUTIVE OVERVIEW................................................................................................... 1 SIDS DATA PROFILE.......................................................................................................... 7 SIDS DATA SUMMARY..................................................................................................... 8 1. GENERAL INFORMATION.................................................................................... 10 2. PHYSICAL CHEMICAL DATA.............................................................................. 13 3. ENVIRONMENTAL FATE AND PATHWAYS..................................................... 16 4. ECOTOXICITY......................................................................................................... 18 5. TOXICITY................................................................................................................. 22 6. REFERENCES .......................................................................................................... 28 APPENDICES Appendix A SIDS Data Availability Summary Appendix B SIDS Data Summaries for the Salt Compounds Category: Calcium Sulfate, Potassium Chloride, Potassium Magnesium Sulfate, Potassium Sulfate, Potassium Nitrate, and Potassium Sodium Nitrate ACRONYMS AND ABBREVIATIONS BCF Bioconcentration Factor bw Body Weight DAP Diammonium Phosphate DOT Department of Transportation FDA U. S. Food and Drug Administration g/ L Grams per Liter GLP Good Laboratory Practices GTSP Granular Triple Super Phosphate g/ mL Grams per Milliliter HSDB Hazardous Substance Data Bank IPCS International Programme for Chemical Safety KNO3 Potassium Nitrate Koc Organic Carbon Partition Coefficient Kow Octanol/ Water Partition Coefficient LC50 Median Lethal Concentration LD50 Median Lethal Dose LOAEL Lowest Observable Adverse Effect Level LOEC Lowest Observable Effect Concentration LOEL Lowest Observable Effect Level M Molar MAP Monoammonium Phosphate mg/ kg Milligrams per Kilogram mg/ kg/ day Milligrams per Kilogram per Day mg/ L Milligrams per Liter MHb Methyl Hemoglobin mm Hg Millimeters of Mercury mmol/ L Millimoles per Liter NaNo3 Sodium Nitrate NFPA National Fire Prevention Association ( NH4) 2NO3 Ammonium Nitrate NIOSH National Institute for Occupational Safety and Health NO3 Nitrate NOAEL No Observable Adverse Effect Level NOEC No Observable Effect Concentration NOEL No Observable Effect Level OECD Organisation for Economic Co operation and Development Pa Pascal ppm Parts per Million SCAS Semi Continuous Activated Sludge SIDS Screening Information Data Set SSP Single Super Phosphate TLm Median Toxicity Level TLV Threshold Limit Value TFI The Fertilizer Institute UAN Urea Ammonia Nitrogen 1 Potassium Sulfate CAS # 7778 80 5 EXECUTIVE OVERVIEW I. Introduction The Fertilizer Institute, on behalf of its member companies, initiated a Product Testing Project to collect, review, summarize, and where necessary develop additional health and environmental safety data for 23 of its high production volume inorganic fertilizer materials. These data and summaries provide valuable information that can be used to update Material Safety Data Sheets, answer customers' questions, and support product stewardship efforts. The chemical industry is also participating in a voluntary program of comparable scope for high production volume organic chemicals. 1 The 23 fertilizer materials were divided into five categories ( i. e., ammonia compounds, nitrate compounds, phosphate compounds, salts and acids) based on their primary constituents as shown in Table 1. The use of categories is a recognized and accepted method that allows health and environmental safety data from one chemical in the category to be used to represent one or more other related chemicals in the category ( USEPA 1999). The key is to find similar, or at least predictable, patterns and trends among the chemicals in a category. In this way, data can be pooled, resources are optimized, and fewer animals are used in testing, all without losing the ability to evaluate the hazards and safety of the individual chemicals. Note that some of the materials fall into more than one category ( e. g., diammonium phosphate [ DAP] is in both the phosphate and ammonia categories).

Searches were conducted using on line databases, standard scientific data compendia, and other published sources for toxicity, ecotoxicity, environmental fate, and physicalchemical properties. The collected data were reviewed for quality and acceptability and then summarized according to the Organization for Economic Cooperation and Development ( OECD) Screening Information Data Set ( SIDS) dossier format ( OECD 1997). The OECD countries ( including the United States) have agreed on a set of tests and on types of data that are generally necessary to characterize the chemical behavior and potential hazards of chemicals released into the environment. The OECD SIDS dossier was chosen as a standard format for the TFI Product Testing Project in order that it would be scientifically defensible, broadly applicable and easily understandable to a wide range of stakeholders.

The following sections of this Executive Overview provide: the rationale for development of the Salts Compounds category ( Section II); a synopsis of the available data related to the physical chemical properties, environmental fate, ecotoxicity and toxicity of salts ( Section III); and a conclusion regarding the adequacy of the data to sufficiently characterize the category and the need for additional testing ( Section IV).

The data for potassium sulfate are summarized in the Chemical Profile and Data Summary tables. Because the evaluation of data adequacy relies on a category approach, the Data Summary table references Appendix B when data are available for one or more 1 HPV Chemical Challenge Program; USEPA 1999 ( http:// www. epa. gov/ opptintr/ chemrtk/ volchall. htm) 2 Potassium Sulfate CAS # 7778 80 5 of the other materials in the category for those data elements where no data specific to potassium sulfate are available. Appendix B provides a summary of the data for all of the salts compounds in the category. The individual studies for potassium sulfate itself are presented in subsequent pages of this document. Separate data summary documents are available for each of the salts compounds in the category.

II. Rationale for the Salts Compounds Category The salts compounds category for fertilizer materials includes calcium sulfate, potassium chloride, potassium magnesium sulfate, potassium sulfate, potassium nitrate, and potassium sodium nitrate. Salts are grouped together primarily because of their similar chemical composition and physical chemical properties, including their propensity to dissociate in aquatic systems. The compounds have similar and generally predictable patterns of behavior in the environment as well as toxicological properties. The toxicity of salts can vary dependent on the toxicity of the individual cations and anions, although the available data indicate that salts as a group are not particularly toxic.

III. Summary of Data Available for the Salts Compounds Category Detailed data summaries for potassium sulfate are included in subsequent sections of this Health and Environmental Safety Data Summary Document for Potassium Sulfate. These data are briefly summarized here.

Physical Chemical Data Sufficient coverage of physical chemical properties exists across the category, with the exception of vapor pressure and Kow. However, these data are less critical for understanding the behavior of inorganic salts. Melting points are high, ranging from 334 to over 1400 º C. Densities are in the range of about 2 3 g/ mL. Inorganic salts are generally highly soluble in water, with values ranging from 2 to 357 g/ L at 20 25oC. In addition, these compounds dissociate and exist at around neutral pHs in aqueous solutions.

Environmental Fate and Pathway Specific environmental fate and transport studies are rarely conducted for these specific compounds. This is because salts are well known to dissociate in the environment. The sulfur and nitrogen cycles are well understood, and the available data for calcium sulfate and potassium nitrate support this understanding. Similarly, the fate and behavior of the cations ( potassium, magnesium, calcium, sodium) are equally understood. These chemicals are neither bioaccumulative nor persistent in the environment.

Ecotoxicity Substantial data are available to describe the acute toxicity of these salts to fish, Daphnia, and aquatic plants. Data from the literature indicate LC50 values ranging from about 680 3 Potassium Sulfate CAS # 7778 80 5 to over 3,500 mg/ L for fish, 337 to over 1,970 mg/ L for Daphnia, and about 1,300 to 3,200 mg/ L for algae. Additional, acute fish studies were conducted using OECD protocols under Good Laboratory Practice ( GLP) conditions on the two combinations of salts ( potassium magnesium sulfate and potassium sodium nitrate). Results of these two studies demonstrated no observable toxic effects at the highest concentrations tested. Based on the standard Federal Insecticide Fungicide and Rodenticide Act ( FIFRA) acute toxicity ratings for fish and Daphnia ( below), the compounds in this category are considered practically non toxic.

EC/ LC50 ( mg/ L) Toxicity Description < 0.1 Very Highly Toxic 0.1 1 Highly Toxic 1 10 Moderately Toxic 10 100 Slightly Toxic > 100 Practically Non Toxic Mammalian Toxicity Acute toxicity Acute oral toxicity has been well studied in the discrete compounds of the category. The data indicate an absence of acute toxicity, with literature LD50 values ranging from about 1,500 to over 6,600 mg/ kg bw. The lack of significant acute toxicity was confirmed in studies conducted on the two salt combinations ( potassium magnesium sulfate and potassium sodium nitrate), which were tested via the oral exposure route, and potassium nitrate, which was tested via dermal exposure. Results of these studies indicate no toxicity at the highest doses tested ( 2,000 and 5,000 mg/ kg bw for the oral and dermal routes, respectively). Similarly, the limited dermal irritation data indicate an absence of skin irritation and toxicity. Inhalation data are not available, but this is not expected to be a significant exposure route for inorganic salts. Based on the standard FIFRA acute toxicity ratings for mammals ( below), the compounds in this category are considered to be of low to very low toxicity ( 40 CFR 156.62).

Toxicity Category I II III IV Toxicity Rating High Moderate Low Very Low Oral LD50   50 mg/ kg > 50 500 mg/ kg > 500 5000 mg/ kg > 5000 mg/ kg Dermal LC50   200 mg/ kg > 200 2000 mg/ kg > 2000 20,000 mg/ kg > 20,000 mg/ kg Inhalation LC50   0.2 mg/ L > 0.2 2 mg/ L > 2 20 mg/ L > 20 mg/ L Genotoxicity 4 Potassium Sulfate CAS # 7778 80 5 Some genotoxicity data were available in the literature, with potassium chloride showing some small effects in older studies and potassium nitrate testing negative. To better define the potential for mutagenicity of salts in the category, additional bacterial ( Ames test) and non bacterial ( chromosome aberration) in vitro genetic toxicity tests were conducted on potassium sulfate and calcium sulfate under GLP conditions. For both compounds, results were negative for mutagenicity in the Ames test and chromosome aberration test.

Repeated dose and developmental toxicity Data from the literature indicate that potassium nitrate was tested for mammalian reproductive, developmental, and teratogenic toxicity. Minimal effects were observed at relatively high doses. Furthermore, no teratogenic effects were observed in chick eggs injected with potassium sulfate in a non standard study. Additional long term studies were conducted on two salts compounds because the repeated dose and reproductive data are sparse for the category, and because of the effects noted at high doses in the potassium nitrate literature data. The OECD Guideline 422 combined study, which provides data on repeated dose, reproductive, and developmental endpoints, was conducted under GLP conditions on potassium nitrate and potassium sulfate. Male and female rats were given oral exposures of up to 1,500 mg/ kg/ day by gavage for up to 53 days. No adverse effects were observed on any of the general toxicity or reproductive/ developmental endpoints for either potassium nitrate or potassium sulfate. The resulting NOAELs for both studies, therefore, are 1,500 mg/ kg/ day.

IV. Conclusion for the Salts Compounds Category Substantial data are available for the critical acute aquatic and mammalian toxicity endpoints for the salts category. Additional studies were conducted on calcium sulfate, potassium magnesium sulfate, potassium sulfate, potassium nitrate, and potassium sodium nitrate in order to complete the database for key endpoints. Overall, the data indicate that these compounds are practically non toxic to aquatic organisms and of low to very low toxicity to mammals. Additional testing is not considered necessary to characterize the hazards of these chemicals. 5 Potassium Sulfate CAS # 7778 80 5 TABLE 1: CATEGORIES FOR PRODUCT TESTING PROJECT CATEGORY COMPOUND CAS NUMBER Ammonia Compounds Anhydrous ammonia Aqua ammonia Ammonium nitrate Ammonium sulfate Ammonium thiosulfate Nitrogen solutions ( UAN) Ammonium phosphate sulfate Diammonium phosphate ( DAP) Monoammonium phosphate ( MAP) Urea 7664 41 7 1336 21 6 6484 52 2 7783 20 2 7783 18 8 15978 77 5 12593 60 1 7783 28 0 7722 76 1 57 13 6 Nitrate Compounds Sodium nitrate Ammonium nitrate Potassium nitrate Potassium sodium nitrate Nitrogen solutions ( UAN) 7631 99 4 6484 52 2 7757 79 1 7757 79 1/ 7631 99 4 15978 77 5 Phosphate Compounds Diammonium phosphate ( DAP) Monoammonium phosphate ( MAP) Liquid polyphosphate Single superphosphate** Granular triple superphosphate** 7783 28 0 7722 76 1  8011 76 5 65996 95 4 Salts Potassium chloride Potassium magnesium sulfate Potassium nitrate Potassium sodium nitrate Potassium sulfate Calcium sulfate 7447 40 7 14168 73 1 7757 79 1 7757 79 1/ 7631 99 4 7778 80 5 7778 18 9 Acids Phosphoric acid Nitric acid Sulfuric acid 7664 38 2 7697 37 2 7664 93 9 * = Nitrogen solutions are represented largely by Urea Ammonia Nitrogen ( UAN; 15978 77 5) ** = Single superphosphate and granular triple superphosphate are combined into a single dossier.  = No CAS number readily available 6 Potassium Sulfate CAS # 7778 80 5 V. REFERENCES CITED 40 CFR 156.62. Toxicity Category.

OECD. 1997. SIDS Manual. OECD Secretariat, 3rd Revision, July 1997.

USEPA. 1999. Development of Chemical Categories in the HPV Challenge Program. www. epa. gove/ chemrtk/ catdoc29. pdf. 7 Potassium Sulfate CAS # 7778 80 5 SIDS DATA PROFILE Date: January 27, 2003 1.01 A. CAS No. 7778 80 5 1.01 C. CHEMICAL NAME ( OECD NAME) Potassium sulfate 1.01 D CAS DESCRIPTOR Potassium sulfate 1.01 G STRUCTURAL FORMULA K2SO4 OTHER CHEMICAL IDENTITY INFORMATION Not applicable 1.5 QUANTITY Greater than 1 million tonnes per annum 1.7 USE PATTERN Fertilizer, reagent in analytical chemistry, medicine, food additive 1.9 SOURCES AND LEVELS OF EXPOSURE Low human exposure is expected because potassium sulfate is manufactured in closed systems. Exposure to dusts and direct contact with the material is possible during fertilizer applications. ISSUES FOR DISCUSSION The data for potassium sulfate should be evaluated in combination with the other materials in the salts category. 8 Potassium Sulfate CAS # 7778 80 5 SIDS DATA SUMMARY Date: January 27, 2003 POTASSIUM SULFATE ( CAS NO. 7778 80 5) SPECIES PROTOCOL RESULTS PHYSICAL CHEMICAL DATA 2.1 Melting Point 1,069 ° C 2.2 Boiling Point 1,689 ° C 2.3 Density 2.66 g/ mL at 20oC 2.4 Vapor Pressure No data available 2.5 Octanol/ Water Partition Coefficient No data available 2.6A Water Solubility 1,110 g/ L at 20 ° C 2.6B pH value 7 in aqueous solution 2.7 Flash Point Not applicable 2.8 Auto Flammability Not flammable 2.9 Flammability Not flammable 2.10 Explosive Properties Not explosive 2.11 Oxidizing Properties Not an oxidizer 2.12 Oxidation: Reduction Potential See Appendix B results* 2.13A Additional data See text ENVIRONMENTAL FATE and PATHWAY 3.1.1 Photodegradation See Appendix B results* 3.1.2 Stability in Water See Appendix B results* 3.1.3 Stability in Soil Stable 3.3.2 Distribution Calculated, Fugacity Level III 4.5 x 10 9% to air 45.3% to water 54.6% to soil 0.0755% to sediment 3.5 Biodegradation See Appendix B results* 3.7 Bioaccumulation No data available ECOTOXICITY 4.1 Acute Toxicity to Fish Lepomis macrochirus 96 hrs LC50 = 3,550 mg/ L Pimephales promelas 96 hrs LC50 = 680 mg/ L 4.2 Acute Toxicity to Aquatic Invertebrates Daphnia magna 48 hrs EC50 = 720 890 mg/ L 4.3 Toxicity to Aquatic Plants ( Algae) Scenedesmus subspicatus 72 hrs EC50 = 1,430 2,900 mg/ L 4.4 Toxicity to Bacteria See Appendix B results* 4.5.1 Chronic Toxicity to Fish See Appendix B results* 4.5.2 Chronic Toxicity to Aquatic Invertebrates See Appendix B results* 4.6.1 Toxicity to Soil Dwelling Organisms No data available 4.6.2 Toxicity to Terrestrial Plants See text 4.6.3 Toxicity to Other Non Mammalian Terrestrial Species Turkey poults 21 days NOEC > 1,000 mg/ L * See Appendix B results for data on other chemicals in the salts category. 9 Potassium Sulfate CAS # 7778 80 5 SPECIES PROTOCOL RESULTS TOXICITY 5.1.1 Acute Oral Toxicity Rat LD50 = 6,600 mg/ kg bw 5.1.2 Acute Inhalation Toxicity No data available 5.1.3 Acute Dermal Toxicity See Appendix B results* 5.1.4 Acute Toxicity, Other Routes Guinea pig Subcutaneous LDLO = 3,000 mg/ kg bw 5.2.1 Skin Irritation/ Corrosion See Appendix B results* 5.2.2 Eye Irritation/ Corrosion See Appendix B results* 5.3 Skin Sensitization See Appendix B results* 5.4 Repeated Dose Toxicity Rat OECD 422 NOAEL = 1,500 mg/ kg/ day 5.5 Genetic Toxicity in vitro . Gene mutation Salmonella typhimurium OECD 471 Negative . Chromosomal aberration Chinese hamster ovaries OECD 473 Negative 5.6 Genetic Toxicity in vivo See Appendix B results* 5.7 Carcinogenicity See Appendix B results* 5.8 Toxicity to Reproduction Rat OECD 422 NOAEL = 1,500 mg/ kg/ day 5.9 Developmental Toxicity/ Teratogenicity Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Chicken eggs LD50 = 5.01 mg/ kg 5.10 Additional Information No sensory irritation 5.11 Human Experience Large doses can induce vomiting if swallowed 1.8 Occupational Exposure Limits TLV as inert dust 15 mg/ m3 * See Appendix B results for data on other chemicals in the nitrate category. 10 Potassium Sulfate CAS # 7778 80 5 1. GENERAL INFORMATION 1.01 SUBSTANCE INFORMATION A. CAS number 7778 80 5 B. Name ( IUPAC name) Potassium sulfate C. Name ( OECD name) Potassium sulfate D. CAS Descriptor Not applicable E. EINECS Number 231 915 5 F. Molecular Formula K2SO4 G. Structural Formula K2SO4 SMILES: KOS(= O)(= O) OK H. Substance Group Not applicable I. Substance Remark Not applicable J. Molecular Weight 174.3 1.02 OECD INFORMATION A. Sponsor Country Not applicable ( would be US)

B. Lead Organization Name of Lead Organization: Not applicable ( would be EPA)

C. Name of Responder Name: Mr. William C. Herz, Director of Scientific Programs Address/ Phones: The Fertilizer Institute Union Center Plaza 820 First Street, NE, Suite 430 Washington, DC 20002 USA Tel: ( 202) 962 0490 Fax: ( 202) 962 0577 11 Potassium Sulfate CAS # 7778 80 5 1.1 GENERAL SUBSTANCE INFORMATION A. Type of Substance element [ ]; inorganic [ X]; natural substance [ ]; organic [ ]; organometallic [ ]; petroleum product [ ]

B. Physical State ( at 20 ° C and 1.013 hPa)

gaseous [ ]; liquid [ ]; solid [ X]

C. Purity 99.99%

1.2 SYNONYMS Sulfuric acid dipotassium salt Dipotassium sulfate Potassium sulphate 1.3 IMPURITIES Remarks: None identified.

1.4 ADDITIVES Remarks: None identified.

1.5 QUANTITY Remarks: Greater than 1 million tonnes per annum. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

1.6 LABELING AND CLASSIFICATION Remarks: No specific labeling. 12 Potassium Sulfate CAS # 7778 80 5 1.7 USE PATTERN A. General Type of Use: Category:

( a) main Wide dispersive use industrial Agriculture industry use Fertilizer ( b) main Non dispersive use industrial Chemical industry use Reagent in analytical chemistry, medicine, food additive, powdered fire extinguishers, lubricants, dyes Remarks: The primary use of potassium sulfate is as a fertilizer and it is the second largest tonnage potassium compound produced. Reference: 1) Hazardous Substances Data Bank ( HSDB). 1999. Potassium Sulfate. National Library of Medicine, Bethesda, MD. 2) United Nations Industrial Development Organization ( UNIDO) and International Fertilizer Development Center ( IFDC). 1998. Fertilizer Manual. Kluwer Academic Publishers, The Netherlands.

B. Uses in Consumer Products Remarks: Limited uses in consumer products. References: Hazardous Substances Data Bank ( HSDB). 1999. Potassium Sulfate. National Library of Medicine, Bethesda, MD.

1.8 OCCUPATIONAL EXPOSURE LIMIT VALUE Exposure limit value Type: 8 hour time weighted average Value: 15 mg/ m3 total dust, 5 mg/ m3 respirable dust Remarks: No specific limits. Treat as inert dust. Reference: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

1.9 SOURCES OF EXPOSURE Remarks: Potassium sulfate can be absorbed into the body by inhalation of its aerosol and by ingestion, although significant human and environmental exposures during 13 Potassium Sulfate CAS # 7778 80 5 manufacture are unlikely if the process is well managed. Engineering controls such as mechanical ventilation, process or personnel enclosure, control of process conditions, and process modifications significantly reduce exposure. Local exhaust ( ventilation) control as close to the point of generation is both the most economical and safest method to minimize personnel exposure to airborne concentrations. Personal protective equipment includes neoprene or nitrile gloves, dusk masks or fume hoods as appropriate, chemical safety goggles, and impervious apron, sleeves and boots. Field exposure to workers is possible when handling and using on farms as a fertilizer. However, fertilizers are applied by mechanical spreaders, which reduces contact exposure. Environmental releases are controlled at the manufacturing plant. Gaseous emissions are low due to use of scrubbers and liquid effluent is recovered as much as possible. Exposure to environmental receptors is dependent on the amount used as fertilizer on fields, the climatic conditions, and the hydrological conditions of the area of application.

1.10 ADDITIONAL REMARKS A. Options for disposal Remarks: Potassium sulfate must be disposed of in accordance with federal, state and local environmental control regulations. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2. PHYSICAL CHEMICAL DATA 2.1 MELTING POINT Value: 1,069 ° C Decomposition: Yes [ ] No [ X] Ambiguous [ ] Sublimation: Yes [ ] No [ X] Ambiguous [ ] Method: Not described. GLP: Yes [ ] No [ ] ? [ X] Remarks: At 760 mm Hg References: Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories. 14 Potassium Sulfate CAS # 7778 80 5 2.2 BOILING POINT Value: 1,689 ° C Pressure: at 760 mm Hg Decomposition: Yes [ ] No [ X] Ambiguous [ ] Method: Not described. GLP: Yes [ ] No [ ] ? [ X] References: Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories.

2.3 DENSITY ( Relative Density)

Type: Bulk density [ ]; Density [ X]; Relative Density [ ] Value: 2.66 g/ cm3 Temperature: 20 ° C Method: Not described. GLP: Yes [ ] No [ ] ? [ X] References: Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories.

2.4 VAPOR PRESSURE Remarks: No data available.

2.5 PARTITION COEFFICIENT logPow Remarks: No data available.

2.6 WATER SOLUBILITY A. Solubility Value: 7.35 g/ 100 g; 11.1 g/ 100 g; 12.0g/ 100g; 14.8 g/ 100 g; 24.0 g/ 100 g Temperature: 0; 20; 25; 40; 100 ° C Description: Miscible [ ]; Of very high solubility [ X]; Of high solubility [ ]; Soluble [ ]; Slightly soluble [ ] Of low solubility [ ]; Of very low solubility [ ]; Not soluble [ ] GLP: Yes [ ] No [ ] ? [ X] Remarks: Insoluble in alcohol. Practically insoluble in saturated solution of sulfate ammonium. References: 1) Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories. 15 Potassium Sulfate CAS # 7778 80 5 2) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

B. pH Value, pKa Value pH Value: About 7 Concentration: Aqueous solution Temperature: 25 ° C Method: Not described. GLP: Yes [ ] No [ ] ? [ X] Remarks: The IUCLID Data Sheet reports that a 50 g/ L solution at 20oC has a pH between 5.5 7.5. References: 1) Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories. 2) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2.7 FLASH POINT ( liquids)

Remarks: Not applicable.

2.8 AUTO FLAMMABILITY ( solid/ gases)

Remarks: Not flammable. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2.9 FLAMMABILITY Remarks: Not flammable. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2.10 EXPLOSIVE PROPERTIES Remarks: Not explosive. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition. 16 Potassium Sulfate CAS # 7778 80 5 2.11 OXIDIZING PROPERTIES Remarks: No oxidizing properties. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2.12 OXIDATION: REDUCTION POTENTIAL Remarks: No oxidizing properties. References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

2.13 ADDITIONAL DATA Remarks: When heated to decomposition, it emits toxic fumes of K2O and SOx. It also can react violently with aluminum and magnesium at high temperatures. References: 1) Canadian Center for Occupational Health & Safety. MSDS Database. 1993. 2) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition. 3) Lewis, R. J. 1992. Sax's Dangerous Properties of Industrial Materials 8th ed. Van Nostrand Reinhold, NY.

3. ENVIRONMENTAL FATE AND PATHWAYS 3.1 STABILITY 3.1.1 PHOTODEGRADATION Remarks: No data available.

3.1.2 STABILITY IN WATER Remarks: No data available.

3.1.3 STABILITY IN SOIL Remarks: Potassium and sulfate ions are stable in soil 17 Potassium Sulfate CAS # 7778 80 5 3.2 MONITORING DATA ( ENVIRONMENTAL)

Remarks: No data available.

3.3 TRANSPORT AND DISTRIBUTION BETWEEN ENVIRONMENTAL COMPARTMENTS INCLUDING ESTIMATED ENVIRONMENTAL CONCENTRATIONS AND DISTRIBUTION PATHWAYS 3.3.1 TRANSPORT Remarks: No data available.

3.3.2 THEORETICAL DISTRIBUTION ( FUGACITY CALCULATION)

Method: Fugacity Level III ( Mackay type) Mass Distribution by Environmental Compartment: Air 4.5 x 10 9% Water 45.3% Soil 54.6% Sediment 0.0755%

3.4 IDENTIFICATION OF MAIN MODE OF DEGRADABILITY IN ACTUAL USE Remarks: No data available.

3.5 BIODEGRADATION Remarks: No data available.

3.6 BOD5, COD OR RATIO BOD5/ COD Remarks: No data available.

3.7 BIOACCUMULATION Remarks: No data available. 18 Potassium Sulfate CAS # 7778 80 5 4. ECOTOXICITY 4.1 ACUTE/ PROLONGED TOXICITY TO FISH Type of test: Static [ X]; Semi static [ ]; Flow through [ X]; Opensystem [ X]; Closed system [ ] Species: Lepomis macrochirus ( bluegill) Exposure period: 96 hours Results: LC50 = 3,550 mg K2SO4/ L Analytical monitoring: Yes [ ]; No [ X]; ? [ ] Method: Five gallon glass jars containing 20 L of distilled water were placed in a constant temperature tank ( 20oC). Ten fish were placed in each container and tests were run in duplicate for every concentration. Concentrations ranged from 2,400 to 5,600 mg K2SO4/ L. The pH for the various concentrations ranged from 7.16 to 9.2. GLP: Yes [ ] No [ ] ? [ X] Test substance: Analytical or reagent grade potassium sulfate ( K2SO4). Remarks: No fish died at 2,400 mg K2SO4/ L. At 2,800 mg K2SO4/ L, the average survival rate was 90% at 96 hours. At 5,600 mg K2SO4/ L and 96 h, there was 100% mortality. References: Trama, F. B. 1954. The acute toxicity of some common salts of sodium, potassium and calcium to the common bluegill. Proc. Acad. Nat. Sci. Piladelphia. 106: 185 205.

( b) Type of test: Static [ X]; Semi static [ ]; Flow through [ ]; Opensystem [ X]; Closed system [ ] Species: Pimephales promelas Exposure Period: 96 hours Results: LC50 = 680 mg/ L Method: USEPA. 1991. Test temperature was 25oC. GLP: Yes [ X] No [ ] ? [ ] Test substance: Potassium sulfate ( K2SO4) Reference: Mount, D. R., Gulley, D. D., Hockett, R., Garrison, T. D., and Evans, J. M. 1997. Statistical models to predict the toxicity of major ions to Ceriodaphnia dubia, Daphnia magna and Pimephales promelas ( fathead minnows). Environ. Toxicol. Chem. 16: 2009 2019. 19 Potassium Sulfate CAS # 7778 80 5 4.2 ACUTE TOXICITY TO AQUATIC INVERTEBRATES A. Daphnia ( a) Type of test: Static [ X]; Semi static [ ]; flow through [ ]; Opensystem [ X]; Closed system [ ] Species: Daphnia magna Exposure period: 48 hours Results: EC50 = 720 mg/ L Analytical monitoring: Yes [ ]; No [ ]; ? [ X] Method: USEPA. 1991. All tests were conducted in 30 mL plastic beakers containing 10 mL of test solution and five D. magna. Test solutions were 500, 1,000, 1,250, 1,500, 2,000, 2,500, 5000, and 10,000 mg/ L. GLP: Yes [ X] No [ ] ? [ ] Test substance: Potassium sulfate ( K2SO4) References: Mount, D. R., Gulley, D. D., Hockett, R., Garrison, T. D., and Evans, J. M. 1997. Statistical models to predict the toxicity of major ions to Ceriodaphnia dubia, Daphnia magna and Pimephales promelas ( fathead minnows). Environmental Toxicology and Chemistry 16: 2009 2019.

( b) Type of test: Static [ X]; Semi static [ ]; flow through [ ]; Other ( e. g. field test) [ ]; Open system [ X]; Closed system [ ] Species: Daphnia magna Exposure period: 48 hours Results: EC50 = 890 mg/ L Analytical monitoring: Yes [ ]; No [ ]; ? [ X] Method: DIN 38412 Part II ( nearly identical to 150/ DIS 6341) 1992. GLP: Yes [ X] No [ ] ? [ ] Test substance: Potassium sulfate ( K2SO4) Remarks: Endpoint is immobility References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

B. Other aquatic organisms Remarks: No data available. 20 Potassium Sulfate CAS # 7778 80 5 4.3 TOXICITY TO AQUATIC PLANTS, e. g. algae Species: Scenedesmus subspicatus Endpoint: Biomass [ X]; Growth rate [ ]; Other [ ] Exposure period: 72 hours Results: EC50 = 1430 2900 mg/ L Analytical monitoring: Yes [ ]; No [ ]; ? [ X] Method: DIN 38412 Part 33   Determination of the nonpoisonous effect of waste water to green algae ( Scenedesmus chlorophyll fluorescence test) by dilution limits. GLP: Yes [ ] No [ ] ? [ X] Test substance: Potassium sulfate ( K2SO4) References: European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

4.4 TOXICITY TO BACTERIA Remarks: No data available.

4.5 CHRONIC TOXICITY TO AQUATIC ORGANISMS 4.5.1 CHRONIC TOXICITY TO FISH Remarks: No data available.

4.5.2 CHRONIC TOXICITY TO AQUATIC INVERTEBRATES Remarks: No data available.

4.6 TOXICITY TO TERRESTRIAL ORGANISMS 4.6.1 TOXICITY TO SOIL DWELLING ORGANISMS Remarks: No data available.

4.6.2 TOXICITY TO TERRESTRIAL PLANTS Species: Cotton Method: A field study using cotton was conducted on a Lucy loamy sand from 1993 to 1995. Sources of applied 21 Potassium Sulfate CAS # 7778 80 5 sulfur were ammonium sulfate, elemental S, potassium sulfate, potassium magnesium sulfate, and potassium thiosulfate. Rates of applied S were 0, 10, 20, and 40 lb/ acre. All sources at each rate were preplant broadcast applications. All treatments received total annual applications of 90 lb N/ acre, 60 lb PO5/ acre, and 140 lb K2O/ acre. Upper most mature cotton leaves were collected at early bloom for S analysis. Seed cotton yields were determined at maturity by machine harvesting the two center rows from each plot. Fiber properties evaluated included micronaire, length, length uniformity, strength, elongation, trash uniformity, and color. Prior to testing, soil samples were taken to determine background levels of extractable S. GLP: Yes [ ] No [ ] ?[ X] Test substance: Potassium sulfate ( K2SO4) Remarks: Lint yields were increased by the rate of S, but were not affected by the source of S, the time of S application, or the interaction between source and rate. Applying 20 lb S/ acre increased lint yields by an average of 15 to 26% depending on the year. A linear response to S rate in 1994 was attributed to the high rainfall received in July and a probably leaching of some of the applied S in this sandy soil. The quadratic responses observed in 1993 and 1995 were probably attributed to drought conditions. Potassium sulfate produced slightly lower yields than ammonium sulfate and potassium magnesium sulfate. In 1995, fiber length was increased slightly the application of S. Fiber length was also affected by the interaction between source and rate, but there were no consistent differences among sources across rates. Concentration of S in cotton leaves collected at mid bloom increased with the rate of applied S during the study. In 1994 and 1995, there was a significant interaction between rate and time of application for S concentration in leaves. Sulfur applications at early squaring resulted in higher S concentrations than preplant treatments. References: Mullins, G. L. 1998. Cotton response to the rate and source of sulfur on a sandy coastal plain soil. Journal of Production Agriculture 11( 1): 214 218.

4.6.3 TOXICITY TO OTHER NON MAMMALIAN TERRESTRIAL SPECIES ( INCLUDING AVIAN)

Species: Nicholas Large White turkey poults Endpoint: Mortality [ ]; Reproduction rate [ ]; Weight [ X]; Other [ X] Exposure period: 21 days Results: NOEC > 1000 mg/ L 22 Potassium Sulfate CAS # 7778 80 5 Method: Turkey poults were fed experimental diets from 0 to 21 days of age. The basal diet was deficient in sulfur amino acids. Treatments included no supplemental sulfate, 0.1% ( 1000 ppm) of K2SO4 and 0.1% K2 MgSO4. Supplemental methionine was 0, 0.1, and 0.15%. At day one a total of 288 poults were assigned to 36 pens. Individual body weights were obtained at 21 days of age and food consumed during the experiment was measured. GLP: Yes [ ] No [ X] ? [ ] Test substance: Potassium sulfate ( K2SO4), Potassium magnesium sulfate ( K2 MgSO4) Remarks: The addition of K2SO4 to diets without supplemental methionine resulted in significantly increased body weight, but did not influence feed efficiency. The addition of either K2SO4 or K2 MgSO4 to the diet containing 0.1% methionine resulted in a further increase in growth compared to the unsupplemented control diet, indicating that they can spare a portion of the sulfur amino acid requirement in the diet of turkey poults. References: Miles, R. D. and Harms, R. H. 1983. Benefit from the supplementation of K2SO4 or K2 MgSO4 to the diet of turkey poults. Nutrition Reports International 28( 2): 381 384.

4.7 BIOLOGICAL EFFECTS MONITORING ( INCLUDING BIOMAGNIFICATION)

Remarks: No data available.

4.8 BIOTRANSFORMATION AND KINETICS Remarks: No data available.

5. TOXICITY 5.1 ACUTE TOXICITY 5.1.1 ACUTE ORAL TOXICITY Type: LD0 [ ]; LD100 [ ]; LD50 [ X]; LDL0 [ ]; Other [ ] Species/ strain: Rat Value: 6,600 mg/ kg bw Method: Not described 23 Potassium Sulfate CAS # 7778 80 5 GLP: Yes [ ] No [ ] ? [ X] Test substance: Potassium sulfate ( K2SO4) References: 1) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition. 2) Hazardous Substances Data Bank ( HSDB). 1999. Potassium Sulfate. National Library of Medicine, Bethesda, MD. 3) Registry of Toxic Effects of Chemical Substances ( RTECS). 1999. Potassium Chloride.

5.1.2 ACUTE INHALATION TOXICITY Remarks: No data available.

5.1.3 ACUTE DERMAL TOXICITY Remarks: No data available.

5.1.4 ACUTE TOXICITY BY OTHER ROUTES OF ADMINISTRATION Type: LD0 [ ]; LD100 [ ]; LD50 [ ]; LDL0 [ X]; Other [ ] Species/ strain: Guinea pig Route of Administration: i. m. [ ]; i. p. [ ]; i. v. [ ]; Infusion [ ]; s. c. [ X]; Other [ ] Exposure period: Not identified Value: 3,000 mg/ kg bw. Method: Not specified GLP: Yes [ ] No [ ] ? [ X] Test substance: Potassium sulfate ( K2SO4) References: 1) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition. 2) Registry of Toxic Effects of Chemical Substances ( RTECS). 1999. Potassium Chloride.

5.2 CORROSIVENESS/ IRRITATION 5.2.1 SKIN IRRITATION/ CORROSION Remarks: No data available.

5.2.2 EYE IRRITATION/ CORROSION Remarks: No data available. 24 Potassium Sulfate CAS # 7778 80 5 5.3 SKIN SENSITIZATION Remarks: No data available.

5.4 REPEATED DOSE TOXICITY Species: Rat Sex/ Strain: Male/ Female Crl: CD( SD) IGS BR Route of Administration: Gavage Exposure Period: Animals in the study were divided between two subgroups ( toxicity and reproductive subgroups). The exposure period for males and females in the toxicity subgroup was 28 days. The exposure period for reproductive subgroup males was at most 28 days. The exposure period for reproductive subgroup females was at most 53 days ( 14 days pre mating, 14 days mating, and gestational and lactational periods up to lactation day 4). Frequency of Treatment: Daily Doses: 0, 50, 750, and 1,500 mg/ kg/ day ( Doses were selected based on parameters assessed in a range finding study at concentrations up to 1,000 mg/ kg/ day) NOAEL: 1,500 mg/ kg/ day ( general toxicity) 1,500 mg/ kg/ day ( reproduction/ developmental toxicity) LOAEL: No adverse effects were seen on general toxicity endpoints. No adverse effects were seen on reproduction/ developmental toxicity endpoints GLP: Yes Method: Toxicity subgroup: Animals comprising the toxicity subgroup ( 5 males and 5 females per dose group) were administered K2SO4 for 28 days ( 7 days/ week) via gavage administration. Among toxicity subgroup animals, functional observations ( sensory reactivity, grip strength, motor activity) were conducted during the final days of treatment. Bleeds for hematology and blood chemistry were conducted on Day 28 of treatment. Organ weights were recorded at termination and major organs and tissues ( and any other abnormalities observed at necropsy) were processed for microscopic examination. Reproductive subgroup: Male rats ( 5 males) in the reproductive subgroup were administered K2SO4 for 28 days via oral gavage. Female rats ( 10 females) in the reproductive subgroup were administered K2SO4 for a period encompassing approximately 53 continuous days via oral gavage: 14 days of initial treatment, plus a maximum of 14 days of cohabitation to ensure mating, and 25 days to litter and rear their young until Day 4 of age. Histology for reproductive subgroup animals was 25 Potassium Sulfate CAS # 7778 80 5 restricted to retained reproductive organs ( and any other abnormalities observed at necropsy). Result: Toxicity subgroup: There were no treatment related deaths and no signs of overt clinical toxicity. There were no effects on body weight, food consumption, or food efficiency. Functional observational battery ( FOB) and motor activity tests identified no treatment related changes in behavior, function, or motor activity. Dams at 1,500 mg/ kg/ day experienced slightly lower food consumption and body weight than the controls during the gestation period only. Because of their moderate and transient nature, these observable effects were considered a LOEL rather than a LOAEL. No treatmentrelated histopathological changes were reported. Reproductive subgroup: There were no treatmentrelated deaths and no signs of overt clinical toxicity. There were no effects on body weight, food consumption, or food efficiency. Mating performance and fertility were unaffected by treatment. All animals mated within 4 days. There were no treatment related effects on gestation length, gestation index, litter size, offspring survival indices, sex ratio, offspring bodyweight, or macropathology for offspring. Test Substance: Potassium Sulfate ( K2SO4) Remarks: Due to a shortage of test substance, additional substance with equivalent composition was obtained and used in the latter phase of the study. Reference: Product Safety Laboratories. 2002. Potassium Sulfate: Combined Repeated Dose Toxicity Study With the Reproduction/ Developmental Toxicity Screening Test ( Oral Gavage Study in Rats). Study Number 11772.

5.5 GENETIC TOXICITY IN VITRO A. Bacterial Test Type: Bacterial reverse mutation assay System of testing: Species/ strain: S. typhimurium TA98, TA100, TA1535, TA1537 and E. coli WP2 uvrA Concentration: 75, 200, 600, 1,800, and 5,000 µ g/ plate Metabolic activation: With [ ]; Without [ ]; With and Without [ X]; No Data [ ] Results: Cytotoxicity conc: With metabolic activation: None observed Without metabolic activation: None observed Precipitation conc: None observed Genotoxic effects: + ?  With metabolic activation: [ ] [ ] [ X] Without metabolic activation: [ ] [ ] [ X] 26 Potassium Sulfate CAS # 7778 80 5 Method: OECD Guideline 471 ( Ninth Addendum; February 1998) GLP: Yes [ X] No [ ] ? [ ] Test substance: Potassium sulfate, purity: 100% Remarks: When vortexed for more than 1 minute, the test article was soluble and clear in water at approximately 50 mg/ mL, the maximum concentration tested. References: Wagner, V. O. and Klug, M. L. 2001. Bacterial Reverse Mutation Assay: Potassium Sulfate. BioReliance Study No. AA43RD. 503. BTL.

B. Non bacterial in vitro test Type: Mammalian chromosome aberration test System of testing: Species/ strain: Chinese hamster ovaries Concentration: 217.5, 435, 870, and 1,740 µ g/ mL Metabolic activation: With [ ]; Without [ ]; With and Without [ X]; No Data [ ] Results: Cytotoxicity conc: With metabolic activation: None Without metabolic activation: None Precipitation conc: None Genotoxic effects: + ?  With metabolic activation: [ ] [ ] [ X] Without metabolic activation: [ ] [ ] [ X] Method: OECD Guideline 473 ( Ninth Addendum; February 1998) GLP: Yes [ X] No [ ] ? [ ] Test substance: Potassium sulfate, purity: 100% Remarks: The test article was soluble in water at a concentration of 17.4 mg/ mL, the maximum concentration tested. References: Gudi, R. and Brown, C. 2001. In Vitro Mammalian Chromosome Aberration Test: Potassium Sulfate. BioReliance Study No. AA43RD. 331. BTL.

5.6 GENETIC TOXICITY IN VIVO Remarks: No data available.

5.7 CARCINOGENICITY Remarks: No data available.

5.8 TOXICITY TO REPRODUCTION Remarks: See the summary in Section 5.4 for details of an OECD Guideline 422 combined repeat 27 Potassium Sulfate CAS # 7778 80 5 dose/ reproductive/ developmental toxicity study conducted in 2002 5.9 DEVELOPMENTAL TOXICITY/ TERATOGENICITY ( a) Remarks: See the summary in Section 5.4 for details of an OECD Guideline 422 combined repeat dose/ reproductive/ developmental toxicity study conducted in 2002 ( b) Species/ strain: Single comb White Leghorn chick eggs Sex: Female [ ]; Male [ ]; Male/ Female [ ]; Not applicable [ X] Route of Administration: The test compound was dissolved or suspended in an appropriate vehicle and injected into the yolk and through the air cell Duration of the test: 4 days Exposure period: 4 days Doses: Up to 10.0 mg/ egg Control group: Yes [ X]; No [ ]; No Data [ ] Concurrent no treatment [ X]; Concurrent vehicle [ ]; Historical [ ] Results: LD50 ( 96 h) = 5.01 mg/ egg Method: Potassium sulfate was administered into both the yolk and through the air cell. For both injection routes, eggs were treated at 0 hours ( preincubation) and at 4 days. Groups of 20 or more eggs were treated under these four conditions at a minimum of four dose levels. Percentage mortality and number of mortalities were recorded. GLP: Yes [ ] No [ ] ? [ X] Test substance: Potassium sulfate ( K2SO4) Remarks: Potassium sulfate showed no teratogenic response under any of the four conditions. References: Verrett, M. J., Scott, W. F., Reynaldo, E. F., Alterman, E. K., and Thomas, C. A. 1980. Toxicity and teratogenicity of food additive chemicals in the developing chicken embryo. Toxicology and Applied Pharmacology 56: 265 273.

5.10 OTHER RELEVANT INFORMATION Remarks: Cattle that broke into a field that had been treated with potassium sulfate died within two days. Symptoms included prostration, paresis, hypothermia, cessation of rumination, and constipation. No information on the treatment levels of K2SO4 were given. 28 Potassium Sulfate CAS # 7778 80 5 Reference: 1) European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition. 2) Hazardous Substances Data Bank ( HSDB). 1999. Potassium Sulfate. National Library of Medicine, Bethesda, MD.

5.11 EXPERIENCE WITH HUMAN EXPOSURE Results: Swallowing large doses can induce vomiting and cause severe gastrointestinal irritation. Reference: Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories.

6. REFERENCES Budavari, S. ( ed.). 1996. Merck Index. 12th ed. Whitehouse Station: Merck Research Laboratories.

Canadian Center for Occupational Health & Safety. MSDS Database. 1993.

European Commission. 2000. Potassium sulfate. International Uniform Chemical Information Database. Year 2000 CD ROM edition.

Gudi, R. and Brown, C. 2001. In Vitro Mammalian Chromosome Aberration Test: Potassium Sulfate. BioReliance Study No. AA43RD. 331. BTL.

Hazardous Substances Data Bank ( HSDB). 1999. Potassium Sulfate. National Library of Medicine, Bethesda, MD.

Lewis, R. J. 1992. Sax's Dangerous Properties of Industrial Materials 8th ed. Van Nostrand Reinhold, NY.

Miles, R. D. and Harms, R. H. 1983. Benefit from the supplementation of K2SO4 or K2 MgSO4 to the diet of turkey poults. Nutrition Reports International 28( 2): 381 384.

Mount, D. R., Gulley, D. D., Hockett, R., Garrison, T. D., and Evans, J. M. 1997. Statistical models to predict the toxicity of major ions to Ceriodaphnia dubia, Daphnia magna and Pimephales promelas ( fathead minnows). Environ. Toxicol. Chem. 16: 2009 2019.

Mullins, G. L. 1998. Cotton response to the rate and source of sulfur on a sandy coastal plain soil. Journal of Production Agriculture 11( 1): 214 218.

Registry of Toxic Effects of Chemical Substances ( RTECS). 1999. Potassium Chloride.

Trama, F. B. 1954B. The acute toxicity of some common salts of sodium, potassium and calcium to the common bluegill. Proc. Acad. Nat. Sci. Piladelphia. 106: 185 205. 29 Potassium Sulfate CAS # 7778 80 5 United Nations Industrial Development Organization ( UNIDO) and International Fertilizer Development Center ( IFDC). 1998. Fertilizer Manual. Kluwer Academic Publishers, The Netherlands.

Verrett, M. J., Scott, W. F., Reynaldo, E. F., Alterman, E. K., and Thomas, C. A. 1980. Toxicity and teratogenicity of food additive chemicals in the developing chicken embryo. Toxicology and Applied Pharmacology 56: 265 273.

Wagner, V. O. and Klug, M. L. 2001. Bacterial Reverse Mutation Assay: Potassium Sulfate. BioReliance Study No. AA43RD. 503. BTL. Potassium Sulfate CAS # 7778 80 5 APPENDIX A   SIDS Data Availability Summary Potassium Sulfate CAS # 7778 80 5 Explanation of Appendix A Appendix A is a SIDS Data Summary table that provides an overview of availability and quality of the data used in this Health and Environmental Safety Data Summary for Potassium Sulfate. Y ( Yes) and N ( No) designations indicate whether data are available that meet the criteria for each column. The columns are described as:

Information: Data exist that were useful for describing the data element. These data may be from standard laboratory tests or from generally recognized published sources or professional experience.

OECD Study: The data were developed using standard OECD or essentially similar ( e. g., EPA harmonized protocols) guidelines.

GLP: The data were developed under standard Good Laboratory Practice provisions. These generally represent the highest quality data.

Other Study: Studies were conducted that could not be definitively identified as following OECD or GLP protocols. These studies were included when they were determined to be of adequate quality and provided relevant information to the characterization of the compound.

Estimation Method: In some cases, data may be estimated using established structure activity relationships. These methods are common for physical chemical parameters such as octanolwater partition coefficients and water solubility.

Acceptable: This column indicates whether the data are deemed acceptable by standard acceptability criteria and professional judgment. Only the data meeting adequacy standards are included in this summary document.

SIDS Testing Recommended: This column indicates whether additional testing is recommended based on an evaluation of the available data summarized in this document. It is generally not necessary to fill all of the apparent data gaps in order to adequately characterize the inherent hazard of chemicals. Information from other data elements and from other chemicals in the category, along with professional judgment, are useful in the final determination of the need for further testing. Potassium Sulfate CAS # 7778 80 5 SIDS DATA AVAILABILITY SUMMARY DATE: January 27, 2003 Potassium Sulfate CAS No. 7778 80 5 Information OECD Study GLP Other Study Estimated Method Acceptable SIDS Testing Recommended STUDY Y/ N Y/ N Y/ N Y/ N Y/ N Y/ N Y/ N PHYSICAL CHEMICAL DATA 2.1 Melting Point Y N N N N Y N 2.2 Boiling Point Y N N N N Y N 2.3 Density Y N N N N Y N 2.4 Vapor Pressure N N N N N  N 2.5 Partition Coefficient N N N N N  N 2.6 Water Solubility Y N N N N Y N pH and pKa Values Y N N N N Y N 2.8 Auto Flammability Y N N N N Y N 2.9 Flammability Y N N N N Y N 2.10 Explosive Properties Y N N N N Y N 2.11 Oxidizing Properties Y N N N N Y N 2.12 Oxidation: Reduction Potential N N N N N  N OTHER P/ C STUDIES RECEIVED Y N N Y N Y N ENVIRONMENTAL FATE and PATHWAY 3.1.1 Photodegradation N N N N Y  N 3.1.2 Stability in Water N N N N N  N 3.1.3 Stability in Soil Y N N N N Y N 3.2 Monitoring Data N N N N N  N 3.3.1 Transport N N N n N  N 3.3.2 Distribution Y N N N Y Y N 3.5 Biodegradation N N N N N  N 3.7 Bioaccumulation N N N N N  N OTHER ENV FATE STUDIES RECEIVED N N N N N  N ECOTOXICITY 4.1 Acute Toxicity to Fish Y N N Y N Y N 4.2 Acute Toxicity to Daphnia Y Y Y N N Y N 4.3 Toxicity to Algae Y N N Y N Y N 4.4 Toxicity to Bacteria N N N N N  N 4.5.1 Chronic Toxicity to Fish N N N N N  N 4.5.2 Chronic Toxicity to Daphnia N N N N N  N 4.6.1 Toxicity to Soil Dwelling Organisms N N N N N  N 4.6.2 Toxicity to Terrestrial Plants Y N N Y N Y N 4.6.3 Toxicity to Birds Y N N Y N Y N OTHER ECOTOXICITY STUDIES RECEIVED N N N N N  N Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate CAS No. 7778 80 5 Information OECD Study GLP Other Study Estimated Method Acceptable SIDS Testing Recommended STUDY Y/ N Y/ N Y/ N Y/ N Y/ N Y/ N Y/ N TOXICITY 5.1.1 Acute Oral Y N N Y N Y N 5.1.2 Acute Inhalation N N N N N  N 5.1.3 Acute Dermal N N N N N  N 5.1.4 Acute Toxicity by other Routes of Administration Y N N Y N Y N 5.2 Skin and Eye Irritation N N N N N  N 5.3 Skin Sensitization N N N N N  N 5.4 Repeated Dose Y Y Y N N Y N 5.5 Genetic Toxicity in vitro . Gene mutation Y Y Y N N Y N . Chromosomal aberration Y Y Y N N Y N 5.6 Genetic Toxicity in vivo N N N N N  N 5.8 Reproduction Toxicity Y Y Y N N Y N 5.9 Development/ Teratogenicity Y Y Y Y N Y N 5.11 Human Experience Y N N Y N Y N OTHER TOXICITY STUDIES RECEIVED N N N N N  N Potassium Sulfate CAS # 7778 80 5 APPENDIX B   SIDS Data Summaries for the Salt Compounds Category: Calcium Sulfate, Potassium Chloride, Potassium Magnesium Sulfate, Potassium Sulfate, Potassium Nitrate, and Potassium Sodium Nitrate SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Calcium Sulfate Potassium Chloride Potassium Magnesium Sulfate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS PHYSICAL CHEMICAL DATA 2.1 Melting Point 1,450 ° C 771 773 ° C 972 ° C 2.2 Boiling Point Decomposes 1,420 1,500 ° C 2.3 Density 2.31 2.97 g/ mL at 20 25oC 1.98 g/ mL 2.4 Vapor Pressure 2.5 Octanol/ Water Partition Coefficient 2.6A Water Solubility 2 2.5 g/ L at 20oC 347 g/ L at 20 ° C 24.4% at 25oC 2.6B pH and pKa values 2 g/ L pH = 7 About 7 7.04 in 5%

solution 2.7 Flash Point Not applicable Not applicable Not applicable 2.8 Auto Flammability Not flammable Not flammable 2.9 Flammability Not flammable Not flammable 2.10 Explosive Properties Not explosive Not explosive 2.11 Oxidizing Properties Not an oxidizer Not an oxidizer 2.12 Oxidation:

Reduction Potential Not an oxidizer Not an oxidizer SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Calcium Sulfate Potassium Chloride Potassium Magnesium Sulfate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS ENVIRONMENTAL FATE and PATHWAY 3.1.1 Photodegradation 3.1.2 Stability in Water Dissociates in water Ions can persist 3.1.3 Stability in Soil See text Binds to clay particles 3.3.2 Distribution Calculated,

Fugacity Level III 1.1 x 10 7% to air 45% to water 54.9% to soil 0.0755% to sediment Calculated,

Fugacity Level III 1.51 x 10 8% to air 45.2% to water 54.7% to soil 0.0755% to sediment 3.5 Biodegradation 3.7 Bioaccumulation Does not bioaccumulate SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Calcium Sulfate Potassium Chloride Potassium Magnesium Sulfate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS ECOTOXICITY 4.1 Acute toxicity to Fish Pimephales promelas 96 hrs LC50 > 1,970 mg/ L Lepomis macrochirus 96 hrs LC50 = 2,010 mg/ L Oncorhynchus mykiss 96 hrs LC50 > 63.6 mg/ L Lepomis macrochirus 96 hrs LC50 > 2,980 mg/ L Daphnia magna EC50 = 337 825 mg/ L Gambusia affinis 96 hrs LC50 > 56,000 mg/ L Physa heterostropha 96 hrs LC50 = 940 mg/ L 4.2 Acute Toxicity to Aquatic Invertebrates Daphnia magna 48 hrs EC50 = 1,970 mg/ L Scenedesmus subspicatus EC50 = 2,500 mg/ L 4.3 Toxicity to Aquatic Plants ( Algae) Nitzschia linearis 120 hrs TLM = 3,200 mg/ L Nitzschia linearis 120 hrs TLm = 1,337 ppm Chlorella vulgaris 3 4 months NOEC = 600 mg/ L 4.4 Toxicity to Bacteria 4.5.1 Chronic Toxicity to Fish Salmo irideus 28 days NOEC > 3,263 mg/ L 4.5.2 Chronic Toxicity to Aquatic Invertebrates 4.6.1 Toxicity to Soil Dwelling Organisms 4.6.2 Toxicity to Terrestrial Plants 4.6.3 Toxicity to Other Non Mammalian Terrestrial Species SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Calcium Sulfate Potassium Chloride Potassium Magnesium Sulfate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS TOXICITY 5.1.1 Acute Oral Toxicity Rat LD50 > 5,000 mg/ kg bw Rat LD50 = 2,600 mg/ kg bw Rat OECD 425 LD50 > 2,000 mg/ kg bw Mouse LD50 > 4,052

4,226 mg/ kg bw Mouse LD50 = 1,500 mg/ kg bw 5.1.2 Acute Inhalation See text 5.1.3 Acute Dermal Toxicity 5.1.4 Acute Toxicity,

Other Routes 5.2.1 Skin Irritation/

Corrosion May be irritating 5.2.2 Eye Irritation/

Corrosion Not irritating 5.3 Skin Sensitization 5.4 Repeated Dose Hamster Intratracheal;

2 yrs LOAEL = 10 mg/ animal 5.5 Genetic Toxicity in vitro . Gene mutation Salmonella typhimurium OECD 471 Negative Saccharo

myces cerevisiae Mitotic recombination NOAEL = 300 mM . Chromosomal aberration Chinese hamster ovaries Negative Mouse lymphoma cells Marginally positive. See text 5.7 Carcinogenicity 5.8 Toxicity to Reproduction 5.9 Development Toxicity/ Teratogenicity 5.10 Additional Information Not cytotoxic SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Calcium Sulfate Potassium Chloride Potassium Magnesium Sulfate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS 5.11 Human Experience See text See text 1.8 Occupational Exposure Limits TLV as inert dust 15 mg/ m3 TLV as inert dust 15 mg/ m3 TLV for inert dust 15 mg/ m3 SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS PHYSICAL CHEMICAL DATA 2.1 Melting Point 1,069 ° C 344oC 2.2 Boiling Point 1,689 ° C 400oC at 760 mm Hg 2.3 Density 2.66 g/ mL at 20oC 2.109 g/ mL at 16oC 2.4 Vapor Pressure EPISUITE V. 3.10 1.39x10 15 hPa at 25oC 2.5 Octanol/ Water Partition Coefficient EPISUITE V. 3.10  0.79 at 25oC 2.6A Water Solubility 1,110 g/ L at 20 ° C 357 g/ L at 25oC 2.6B pH and pKa values 7 in aqueous solution pH ~ 7 at 25oC 2.7 Flash Point Not applicable Not applicable 2.8 Auto Flammability Not flammable Not flammable 2.9 Flammability Not flammable Not flammable 2.10 Explosive Properties Not explosive May explode on contact with reducing agents and/ or impact.

2.11 Oxidizing Properties Not an oxidizer Strong oxidizer 2.12 Oxidation:

Reduction Potential 2.13A Additional data See text SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS ENVIRONMENTAL FATE and PATHWAY 3.1.1 Photodegradation Does not photodegrade Does not photodegrade 3.1.2 Stability in Water Stable 3.1.3 Stability in Soil Stable Stable 3.3.2 Distribution Calculated,

Fugacity Level III 4.5 x 10 9% to air 45.3% to water 54.6% to soil 0.0755% to sediment Fugacity Level III ( Mackay type) 8.34x10 9 % to air 45.3% to water 54.7% to soil 0.0755% to sediment 3.5 Biodegradation Biodegradable 3.7 Bioaccumulation Does not bioaccumulate SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS ECOTOXICITY 4.1 Acute toxicity to Fish Lepomis macrochirus 96 hrs LC50 = 3,550 mg/ L Lepomis macrochirus 96 hrs LC50 = 1,839 mg NO3/ L Oncorhynchus mykiss 96 hrs LC50 > 98.9 mg/ L Pimephales promelas 96 hrs LC50 = 680 mg/ L 4.2 Acute Toxicity to Aquatic Invertebrates Daphnia magna 48 hrs EC50 = 720 890 mg/ L Daphnia magna 48 hrs TLm = 300 mg NO3/ L 4.3 Toxicity to Aquatic Plants ( Algae) Scenedesmus subspicatus 72 hrs EC50 = 1,430

2,900 mg/ L See text 4.4 Toxicity to Bacteria 4.5.1 Chronic Toxicity to Fish 4.5.2 Chronic Toxicity to Aquatic Invertebrates Nereis grubei Neanthes arenaceodentata Dorvilliea articulata Capitella capita TLm = 327 mg NO3/ L TLm = 496 mg NO3/ L TLm = 880 mg NO3/ L TLm = 713 mg NO3/ L 4.6.1 Toxicity to Soil Dwelling Organisms 4.6.2 Toxicity to Terrestrial Plants See text 4.6.3 Toxicity to Other Non Mammalian Terrestrial Species Turkey poults 21 days NOEC > 1,000 mg/ L SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS TOXICITY 5.1.1 Acute Oral Toxicity Rat LD50 = 6,600 mg/ kg bw Rat LD50 = 3,750 mg/ kg bw Rat OECD 425 LD50 > 2,000 mg/ kg bw Rabbit LD50 = 1,166 NO3/ kg Cow, Sheep Lethal dose ( cow)

= 75 140 mg NO3  N/ kg Lethal dose ( sheep) = 70 mg NO3  N/ kg Goat LD100 = 1,000

1,500 mg/ kg 5.1.2 Acute Inhalation 5.1.3 Acute Dermal Toxicity Rat OECD 402 LD50 > 5,000 mg/ kg 5.1.4 Acute Toxicity,

Other Routes Guinea pig Subcutaneous LDLO = 3,000 mg/ kg bw 5.2.1 Skin Irritation/

Corrosion 5.2.2 Eye Irritation/

Corrosion 5.3 Skin Sensitization 5.4 Repeated Dose Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Rat OECD 422 NOAEL = 1,500 mg/ kg/ day SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS 5.5 Genetic Toxicity in vitro . Gene mutation Salmonella typhimurium OECD 471 Negative Salmonella typhimurium Bacterial reverse mutation assay Negative Bacillus subtilis recombination assay Negative . Chromosomal aberration Chinese hamster ovaries OECD 473 Negative 5.6 Genetic Toxicity in vivo Rat 10 weeks Negative 5.7 Carcinogenicity 5.8 Toxicity to Reproduction Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Guinea pig One generation study NOAEL Parental = 10,000 ppm NOAEL F1 Offspring =

10,000 ppm Rat Twogeneration study NOAEL Parental = 2.5%

5.9 Development Toxicity/ Teratogenicity Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Rat OECD 422 NOAEL = 1,500 mg/ kg/ day Chicken eggs LD50 = 5.01 mg/ kg Mouse Oral; 10 day exposure NOAEL > 400 mg/ kg bw 5.10 Metabolism and Toxicokinetics No sensory irritation SIDS DATA SUMMARIES FOR THE SALTS CATEGORY Date: January 27, 2003 Potassium Sulfate CAS # 7778 80 5 Potassium Sulfate Potassium Nitrate Potassium Sodium Nitrate DATA ELEMENTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS SPECIES PROTOCOL RESULTS 5.11 Human Experience Large doses can induce vomiting if swallowed See text 1.8 Occupational Exposure Limits TLV as inert dust 15 mg/ m3 TLV as inert dust 15 mg/ m3


[Federal Register Volume 78, Number 103 (Wednesday, May 29, 2013)]
[Notices]
[Pages 32295-32296]
[FR Doc No: 2013-12693]

=======================================================================
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DEPARTMENT OF TRANSPORTATION

Federal Motor Carrier Safety Administration

[Docket No. FMCSA-2006-26367]

Motor Carrier Safety Advisory Committee (MCSAC); Public Meetings
of the CSA and Motorcoach Subcommittees

AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT.

ACTION: Notice of MCSAC subcommittee meetings.

-----------------------------------------------------------------------

SUMMARY: FMCSA announces that the Motor Carrier Safety Advisory
Committee's (MCSAC) Compliance, Safety, Accountability (CSA), and
Motorcoach Hours of Service (HOS) subcommittees will meet from Monday-
Thursday, June 17-20, 2013, in Arlington, VA. On Monday and Tuesday,
June 17 and 18, the CSA subcommittee will meet to discuss ideas,
concepts, and suggestions on FMCSA's CSA program. On Wednesday and
Thursday, June 19 and 20, the Motorcoach HOS subcommittee will meet to
complete its draft recommendations for the full MCSAC to consider on
hours-of-service for motorcoach drivers. Both meetings are open to the
public for their entirety and there will be a public comment period at
the end of each day.
    Times and Dates: The meetings will be held Monday-Thursday, June
17-20, 2013, from 9 a.m. to 4 p.m., Eastern Daylight Time (E.D.T.). The
meetings will be held at the National Training Center, 1310 N.
Courthouse Road, Suite 600, Arlington, VA 22201.
    Copies of all MCSAC Task Statements and an agenda for the entire
meeting will be made available in advance of the meeting at http://mcsac.fmcsa.dot.gov.

FOR FURTHER INFORMATION CONTACT: Ms. Shannon L. Watson, Senior Advisor
to the Associate Administrator for Policy, Federal Motor Carrier Safety
Administration, U.S. Department of Transportation, 1200 New Jersey
Avenue SE., Washington, DC 20590,<PHONE_NUMBER><EMAIL_ADDRESS>    Services for Individuals with Disabilities: For information on
facilities or services for individuals with disabilities or to request
special assistance at the meeting, contact Luis Mejias at (617) 494-
2041<EMAIL_ADDRESS>by Wednesday, June 12, 2013.

SUPPLEMENTARY INFORMATION:

I. Background

MCSAC

    Section 4144 of the Safe, Accountable, Flexible, Efficient
Transportation Equity Act: A Legacy for Users (SAFETEA-LU, Pub. L. 109-
59, 119 Stat. 1144, August 10, 2005) required the Secretary of
Transportation to establish the MCSAC. The MCSAC provides advice and
recommendations to the FMCSA Administrator on motor carrier safety
programs and regulations, and operates in accordance with the Federal
Advisory Committee Act (FACA, 5 U.S.C. App 2).

Task 12-03: CSA Subcommittee

    The CSA Subcommittee will discuss information, concepts, and ideas
concerning FMCSA's CSA program. The subcommittee will continue its
efforts to:
    1. Identify and make recommendations for enhancements of

the CSA program. These topics should include but not be limited to
Safety Measurement System (SMS) and the interventions/investigative
processes.
    2. Prioritize recommended enhancements of CSA to enable the Agency
to direct its efforts to the most important or timely needs of the
program.

Task 11-06: Motorcoach HOS

    The Motorcoach HOS Subcommittee will meet to discuss information,
concepts, and ideas it believes the full MCSAC should provide to FMCSA
relating to the hours-of-service (HOS) requirements for drivers of
passenger-carrying vehicles. A copy of the full task statement is
posted at FMCSA's Web site: http://mcsac.fmcsa.dot.gov.

II. Meeting Participation

    Oral comments from the public will be heard during the last half-
hour of the meetings each day. Should all public comments be exhausted
prior to the end of the specified period, the comment period will
close. Members of the public may submit written comments on the topics
to be considered during the meeting by Wednesday, June 12, 2013, to
Federal Docket Management System (FDMC) Docket Number FMCSA-2006-26367
using any of the following methods:
     Federal eRulemaking Portal: Go to http://www.regulations.gov. Follow the online instructions for submitting
comments.
     Fax:<PHONE_NUMBER>.
     Mail: Docket Management Facility; U.S. Department of
Transportation, 1200 New Jersey Avenue SE., West Building, Room W12-
140, Washington, DC 20590.
     Hand Delivery: U.S. Department of Transportation, 1200 New
Jersey Avenue SE., Room W12-140, Washington, DC, between 9 a.m. and 5
p.m., E.T. Monday through Friday, except Federal holidays.

    Issued on: May 22, 2013.
 Larry W. Minor,
 Associate Administrator for Policy.
[FR Doc. 2013-12693 Filed 5-28-13; 8:45 am]
BILLING CODE 4910-EX-P


     UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, D.C. 20460

                             OFFICE OF CHEMICAL SAFTEY
AND POLLUTION PREVENTION

RE:  	Meeting with Vertellus and EPA to discuss conditions of use for dicyclohexyl phthalate

List of Documents
 Meeting Summary
 Attendees
Meeting Summary
On October 24, 2019, EPA spoke with Vertellus to discuss use information on dicyclohexyl phthalate (CASRN 84-61-7). EPA provided a general overview of the process of gathering use information under TSCA section 6. Vertellus generally discussed their market and the predominate use of dicyclohexyl phthalate.

Attendees
EPA:
Alex Smith
Claire Brisse
Doug Parsons
Jordan Garbin
Marc Edmonds

Vertellus:
Missy Bogle


[Federal Register: March 28, 2006 (Volume 71, Number 59)]
[Notices]
[Page 15401]
[DOCID:fr28mr06-42]

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DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. CP06-93-000]

ANR Pipeline Company; Notice of Application

March 21, 2006.
    Take notice that on March 15, 2006, ANR Pipeline Company (ANR)
filed an application pursuant to section 7 of the Natural Gas Act (NGA)
for authorization to abandon three injection/withdrawal wells,
Frackelton-Sherwood 21, Lincoln 109, and Lincoln 123, located in the
Lincoln-Freeman Storage Field in Clare County, Michigan, all as more
fully set forth in the application which is on file with the Commission
and open to public inspection. This filing may also be viewed on the
Web at http://www.ferc.gov using the ``eLibrary'' link. Enter the

docket number excluding the last three digits in the docket number
field to access the document. For assistance, call<PHONE_NUMBER> or
TTY,<PHONE_NUMBER>.
    Any questions concerning this application may be directed to Dawn
McGuire, Counsel, ANR Pipeline Company, 1001 Louisiana, Houston, Texas
77002 at<PHONE_NUMBER>.
    There are two ways to become involved in the Commission's review of
this project. First, any person wishing to obtain legal status by
becoming a party to the proceedings for this project should, before the
comment date of this notice, file with the Federal Energy Regulatory
Commission, 888 First Street, NE., Washington, DC 20426, a motion to
intervene in accordance with the requirements of the Commission's Rules
of Practice and Procedure (18 CFR 385.214 or 385.211) and the
Regulations under the NGA (18 CFR 157.10). A person obtaining party
status will be placed on the service list maintained by the Secretary
of the Commission and will receive copies of all documents filed by the
applicant and by all other parties. A party must submit 14 copies of
filings made with the Commission and must mail a copy to the applicant
and to every other party in the proceeding. Only parties to the
proceeding can ask for court review of Commission orders in the
proceeding.
    However, a person does not have to intervene in order to have
comments considered. The second way to participate is by filing with
the Secretary of the Commission, as soon as possible, an original and
two copies of comments in support of or in opposition to this project.
The Commission will consider these comments in determining the
appropriate action to be taken, but the filing of a comment alone will
not serve to make the filer a party to the proceeding. The Commission's
rules require that persons filing comments in opposition to the project
provide copies of their protests only to the party or parties directly
involved in the protest.
    Comments, protests and interventions may be filed electronically
via the Internet in lieu of paper. See, 18 CFR 385.2001(a)(1)(iii) and
the instructions on the Commission's Web site under the ``e-Filing''
link.
    Comment Date: 5 p.m. Eastern Time on April 11, 2006.

Magalie R. Salas,
Secretary.
[FR Doc. E6-4458 Filed 3-27-06; 8:45 am]

BILLING CODE 6717-01-P


[Federal Register Volume 86, Number 216 (Friday, November 12, 2021)]
[Notices]
[Page 62836]
[FR Doc No: 2021-24731]

=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF HOMELAND SECURITY

Federal Emergency Management Agency

[Internal Agency Docket No. FEMA-4608-DR; Docket ID FEMA-2021-0001]

Montana; Amendment No. 1 to Notice of a Major Disaster
Declaration

AGENCY: Federal Emergency Management Agency, DHS.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: This notice amends the notice of a major disaster declaration
for the State of Montana (FEMA-4608-DR), dated August 13, 2021, and
related determinations.

DATES: This change occurred on October 14, 2021.

FOR FURTHER INFORMATION CONTACT: Dean Webster, Office of Response and
Recovery, Federal Emergency Management Agency, 500 C Street SW,
Washington, DC 20472,<PHONE_NUMBER>.

SUPPLEMENTARY INFORMATION: The Federal Emergency Management Agency
(FEMA) hereby gives notice that pursuant to the authority vested in the
Administrator, under Executive Order 12148, as amended, Alana B. Kuhn,
of FEMA is appointed to act as the Federal Coordinating Officer for
this disaster.
    This action terminates the appointment of Jon K. Huss as Federal
Coordinating Officer for this disaster.

    The following Catalog of Federal Domestic Assistance Numbers
(CFDA) are to be used for reporting and drawing funds: 97.030,
Community Disaster Loans; 97.031, Cora Brown Fund; 97.032, Crisis
Counseling; 97.033, Disaster Legal Services; 97.034, Disaster
Unemployment Assistance (DUA); 97.046, Fire Management Assistance
Grant; 97.048, Disaster Housing Assistance to Individuals and
Households In Presidentially Declared Disaster Areas; 97.049,
Presidentially Declared Disaster Assistance--Disaster Housing
Operations for Individuals and Households; 97.050, Presidentially
Declared Disaster Assistance to Individuals and Households--Other
Needs; 97.036, Disaster Grants--Public Assistance (Presidentially
Declared Disasters); 97.039, Hazard Mitigation Grant.

Deanne Criswell,
Administrator, Federal Emergency Management Agency.
[FR Doc. 2021-24731 Filed 11-10-21; 8:45 am]
BILLING CODE 9111-23-P


DuPont Chemicals and Fluoroproducts

Chambers Works

Deepwater, NJ  08023

September 3, 2010

Document Control Office

US Environmental Protection Agency

Office of Pollution Prevention and Toxics

EPA East

Room 6428

1200 Pennsylvania Avenue, NW

Washington, DC 20460

Re: 	EPA – HQ – OPPT – 2003 - 0012

	DuPont Chambers Works NJPDES Permit No. NJ0005100

	PFOA Data Submittal – Outfall DSN662 Weekly Grab Samples

June 2010 Sample Data

Dear Document Control Office:

As per Part IV, Section G.5.a of the NJPDES permit, we are submitting a summary of PFOA analytical results for the weekly grab samples taken at internal outfall DSN662A to NJDEP on a monthly basis. Per your request, we are sending you a paper and electronic copy of the report for samples taken during June 2010. We will continue to send you the reports each month.

If you have any questions, please do not hesitate to call me at (856) 540-3015.

Sincerely,

Joe Greenfield

SHE Consultant – Environmental

DuPont Chambers Works

Enclosures

Copies to:

Director, Chemical Control Division

US Environmental Protection Agency

Office of Pollution Prevention and Toxics

EPA East

Room 4146

1201 Constitution Avenue, NW

Washington, DC 20004

Ms. Susan Rosenwinkel (cover letter only)

Principal Environmental Engineer

NJDEP Division of Water Quality

Bureau of Point Source Permitting – Region 2

401 E. State Street

P.O. Box 029

Trenton, NJ 08625-0029


[Federal Register Volume 79, Number 13 (Tuesday, January 21, 2014)]
[Notices]
[Pages 3471-3472]
[FR Doc No: 2014-00923]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

National Highway Traffic Safety Administration

[Docket No. NHTSA-2013-0133; Notice 1]

General Motors, LLC, Receipt of Petition for Decision of
Inconsequential Noncompliance

AGENCY: National Highway Traffic Safety Administration (NHTSA),
Department of Transportation (DOT).

ACTION: Receipt of petition.

-----------------------------------------------------------------------

SUMMARY: General Motors, LLC (GM) has determined that certain model
year (MY) 2011, 2012 and 2013 Chevrolet Volt passenger cars sold with
windshield sunshades as a ``Limited Personalization Option,'' do not
fully comply with paragraph S4.3 of Federal Motor Vehicle Safety
Standard (FMVSS) No. FMVSS 302, Flammability of Interior Materials. GM
has filed an appropriate report dated August 27, 2013, pursuant to 49
CFR part 573, Defect and Noncompliance Responsibility and Reports.

DATES: The closing date for comments on the petition is February 20,
2014.

ADDRESSES: Interested persons are invited to submit written data,
views, and arguments on this petition. Comments must refer to the
docket and notice number cited at the beginning of this notice and be
submitted by any of the following methods:
     Mail: Send comments by mail addressed to: U.S. Department
of Transportation, Docket Operations, M-30, West Building Ground Floor,
Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590.
     Hand Deliver: Deliver comments by hand to: U.S. Department
of Transportation, Docket Operations, M-30, West Building Ground Floor,
Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590. The
Docket Section is open on weekdays from 10 a.m. to 5 p.m. except
Federal Holidays.
     Electronically: Submit comments electronically by: logging
onto the Federal Docket Management System (FDMS) Web site at http://www.regulations.gov/. Follow the online instructions for submitting
comments. Comments may also be faxed to<PHONE_NUMBER>.
    Comments must be written in the English language, and be no greater
than 15 pages in length, although there is no limit to the length of
necessary attachments to the comments. If comments are submitted in
hard copy form, please ensure that two copies are provided. If you wish
to receive confirmation that your comments were received, please
enclose a stamped, self-addressed postcard with the comments. Note that
all comments received will be posted without change to http://www.regulations.gov, including any personal information provided.
    Documents submitted to a docket may be viewed by anyone at the
address and times given above. The documents may also be viewed on the
Internet at http://www.regulations.gov by following the online
instructions for accessing the dockets. DOT's complete Privacy Act
Statement is available for review in the Federal Register published on
April 11, 2000, (65 FR 19477-78).
    The petition, supporting materials, and all comments received
before the close of business on the closing date indicated below will
be filed and will be considered. All comments and supporting materials
received after the closing date will also be filed and will be
considered to the extent possible. When the petition is granted or
denied, notice of the decision will be published in the Federal
Register pursuant to the authority indicated below.

SUPPLEMENTARY INFORMATION:

I. GM's Petition

    Pursuant to 49 U.S.C. 30118(d) and 30120(h) (see implementing rule
at 49 CFR part 556), GM submitted a petition for an exemption from the
notification and remedy requirements of 49 U.S.C. Chapter 301 on the
basis that this noncompliance is inconsequential to motor vehicle
safety.
    This notice of receipt of GM's petition is published under 49
U.S.C. 30118 and 30120 and does not represent any agency decision or
other exercise of judgment concerning the merits of the petition.

II. Vehicles Involved

    Affected are approximately 3,426 MY 2011, 2012 and 2013 Chevrolet
Volt passenger cars that were manufactured from 12/14/2010 to 06/26/
2013 and sold to retail customers with windshield sunshades as a
``Limited Personalization Option.''

III. Noncompliance

    GM explains that the noncompliance is that the subject vehicles
were delivered as new vehicles to retail customers with windshield
sunshades that do not meet the maximum burn rate requirement of
paragraph S4.3 of FMVSS No. 302.

IV. Rule Text

    Refer to the entire text of Paragraph S4 of FMVSS No. 302 for
contextual restrictions as well as the specific requirements of
subparagraph S4.3.

V. Summary of GM's Analyses

    GM stated its belief that the subject noncompliance is
inconsequential to motor vehicle safety for the following reasons:
    a. When tested as a finished part (i.e., with the inner and outer
layers tested as though they form a composite), the sunshade's burn
rate of 35mm/minute is significantly less than the FMVSS No. 302
maximum burn rate of 102 mm/minute. The outer layer is composed of
self-extinguishing material that meets all of the requirements of FMVSS
No. 302. While the layers of the assembly are not bonded at every point
of contact, they are held together and encased with FMVSS No. 302
compliant self-extinguishing trim and stitching around the entire
perimeter of the sunshade. Additional double rows of stitching create
vertical accordion fold lines in the sunshade. The stitching segments
the inner layer into smaller pieces that

are separated by double layers of the FMVSS No. 302 compliant self-
extinguishing outer layer material.
    b. Only the inner layer, by itself, does not meet the FMVSS No. 302
burn rate, and at 110 mm/minute, it is only marginally above the 102
mm/minute requirement.
    c. The sunshade has a storage bag which is made of FMVSS No. 302
compliant material. When the sunshade is stored in the provided bag
while the vehicle is in use, the external surface that is presented to
the occupant compartment is well within the FMVSS requirement, and two
layers of FMVSS No. 302 compliant material would have to be penetrated
to reach the marginally noncompliant inner layer.
    d. Even if the sunshade was not placed in its storage bag when not
in use, the external surface that is presented to the occupant
compartment is still FMVSS compliant, and this layer would still need
to be penetrated to reach the marginally noncompliant inner layer. In
addition, folding it alone reduces the sunshade's surface area to
approximately one eighth of the unfolded surface area, further reducing
the exposure to any potential ignition source.
    e. GM stated its belief that the purpose of FMVSS No. 302 is ``to
reduce the deaths and injuries to motor vehicle occupants caused by
vehicle fires, especially those originating in the interior of the
vehicle from sources such as matches or cigarettes.'' FMVSS No. 302,
paragraph S.2. The sunshade is designed to be used only when the
vehicle is parked, and it is extremely unlikely that the inner layer
would ever come in contact with an ignition source. As such, it is
extremely unlikely that a vehicle occupant would ever be exposed to a
risk of injury as a result of the noncompliance.
    f. Because the sunshade is intended to help reduce sun load during
hot weather conditions, it may be removed from the vehicle entirely
during colder months, further reducing the exposure of the sunshade to
the interior of the vehicle.
    g. GM stated its belief that NHTSA has previously granted several
inconsequential noncompliance petitions that GM believes can be applied
to a decision on its petition. See GM's petition for a complete
discussion of its reasoning.
    h. There are no known field events involving ignition of sunshades.
GM is not aware of any crashes, injuries or customer complaints
involving this windshield sunshade.
    GM has additionally informed NHTSA that it has corrected the
noncompliance so that all future production vehicles delivered with
windshield sunshades will comply with FMVSS No. 302
    In summation, GM believes that the described noncompliance of the
subject vehicles is inconsequential to motor vehicle safety, and that
its petition, to exempt from providing recall notification of
noncompliance as required by 49 U.S.C. 30118 and remedying the recall
noncompliance as required by 49 U.S.C. 30120 should be granted.
    NHTSA notes that the statutory provisions (49 U.S.C. 30118(d) and
30120(h)) that permit manufacturers to file petitions for a
determination of inconsequentiality allow NHTSA to exempt manufacturers
only from the duties found in sections 30118 and 30120, respectively,
to notify owners, purchasers, and dealers of a defect or noncompliance
and to remedy the defect or noncompliance. Therefore, any decision on
this petition only applies to the subject vehicles that GM no longer
controlled at the time it determined that the noncompliance existed.
However, any decision on this petition does not relieve motor vehicle
distributors and dealers of the prohibitions on the sale, offer for
sale, or introduction or delivery for introduction into interstate
commerce of the noncompliant motor vehicles under their control after
GM notified them that the subject noncompliance existed.

    Authority:  49 U.S.C. 30118, 30120: Delegations of authority at
49 CFR parts 1.95 and 501.8.

Claude H. Harris,
Director, Office of Vehicle Safety Compliance.
[FR Doc. 2014-00923 Filed 1-17-14; 8:45 am]
BILLING CODE 4910-59-P