45240301 Cerven, D. ( 2000) Acute Dermal Toxicity in Rabbits/ LD 50 in Rabbits: XBINX: Lab Project Number: MB 00 8634.02: 1100. Unpublished study prepared by MB Research Laboratories. 14 p. { OPPTS 870.1200}

45410405 Moore, G. ( 2000) Acute Dermal Toxicity Study in Rats Defined Limit Test: Troy EX663: Lab Project Number: 9114: TC0993. Unpublished study prepared by Product Safety Labs. 25 p. { OPPTS 870.1200}

45437102 Parno, J.; Naudascher, P.; Craig, L. ( 2001) Acute Dermal Toxicity Study in Male and Female Rats: Rocima 607: Lab Project Number: OOP 211: 00R 211. Unpublished study prepared by Rohm and Haas Company. 27 p. { OPPTS 870.1200}

45444708 Rana, M. ( 2001) Acute Dermal Toxicity Study of Acticide MBS in Rats: Lab Project Number: 3089. Unpublished study prepared by JAI Research Foundation. 38 p. { OPPTS 870.1200}

45553404 Merkel, D. ( 2001) Acute Dermal Toxicity Limit Test with Dantoserve: ( Rat): Lab Project Number: 10983. Unpublished study prepared by Product Safety Labs. 15 p. { OPPTS 870.1200}

45793603 Merkel, D. ( 2002) Acute Dermal Toxicity Study in Rats Limit Test: Troy EX 680: Lab Project Number: 11077: TC1175: P322. Unpublished study prepared by Product Safety Labs. 24 p. { OPPTS 870.1200}

46287404 Tordo, L.; Rueb, B. ( 2004) Summary of the Acute Toxicity Characteristics of Acticide MBL 5515. Project Number: 042901/ LT/ 81. Unpublished study prepared by Thor GmbH. 5 p.

46603404 Tordo, L.; Rueb, B. ( 2005) Summary of the Acute Toxicity Charateristics of Acticide MBL. Project Number: 050404/ LT/ 81. Unpublished study prepared by Thor GmbH and Acti Chem Specailities, Inc. 5 p.

93053004 McCall, J. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41022102. Proxel Press Paste: Acute Dermal Toxicity to the Rat: CTL Report No. CTL/ P/ 2065; CTL Study No. CR2404. Prepared by ICI Central Toxicology Laboratory. 7 p.

93053014 Pemberton, M.; Leah, A. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 41022102. Proxel Press Paste: Acute Dermal Toxicity to the Rat: CTL Report No. CTL/ P/ 2065; CTL Study No. CR2404. Prepared by ICI Central Toxicology Laboratory. 31 p. 116 870.1300 ( 81 3) Acute inhalation toxicity in rats MRID Citation Reference 42196201 Mould, A. ( 1991) Proxel GXL: 4 Hour Acute Inhalation Toxicity Study in Rat: Lab Project Number: CTL/ P/ 3370. Unpublished study prepared by ICI Americas Inc. 161 p.

42555601 Parr Dobrzanski, R. ( 1992) Proxel BD: Proposed Inhalation Toxicity Study in the Rat: Lab Project Number: CTL/ P/ 3634: HR2091. Unpublished study prepared by ICI Central Toxicology Laboratory. 17 p.

42905103 Parr Dobrzanski, R. ( 1993) Proxel Press Paste: Assessment of Apparent Aerodynamic Particle Size by Air Elutriation: Lab Project Number: CTL/ P/ 4002: TZ0258. Unpublished study prepared by Zeneca Central Toxicology Lab. 15 p.

43585601 Wnorowski, G. ( 1995) Acute Inhalation Toxicity Defined LC50 ( in Rats): IL 2529: Lab Project Numbers: 3277: P330: E40829 1. Unpublished study prepared by Product Safety Labs. 43 p.

43803905 Wnorowski, G. ( 1995) Acute Inhalation Toxicity Defined LC50: Nuosept 495: ( Rats): Lab Project Number: 3850. Unpublished study prepared by Product Safety Labs. 39 p.

45100707 Moore, G. ( 2000) Acute Inalation Toxicity Study in Rats  Limit Test: Nipacide CBX: Lab Project Number: 8291: P330. Unpublished study prepared by Product Safety Labs. 22 p. { OPPTS 870.1300}

45133801 Smith, P. ( 1999) Nuosept 485: Acute ( Four Hour) Inhalation Study in Rats: Lab Project Number: DNN 111/ 992559. Unpublished study prepared by Huntingdon Life Sciences Ltd. 60 p. { OPPTS 870.1300}

45216601 Kirkpatrick, D. ( 2000) Acute Inhalation Toxicity Study of Biochek 410 in Albino Rats: Lab Project Number: WIL 391001. Unpublished study prepared by WIL Research Laboratories, Inc. 69 p. { OPPTS 870.1300}

45236805 Wnorowski, G. ( 1998) Acute Inhalation Toxicity Defined LC( 50) ( in Rats): Mergal K10N: Lab Project Number: 6416: TCO854: P330. Unpublished study prepared by Product Safety Labs. 53 p.

45240302 Cerven, D. ( 2000) Acute Inhalation Toxicity in Rats/ LC 50 in Rats: XBINX: Lab Project Number: MB 00 8634.05: 1300 01. Unpublished study prepared by MB Research Laboratories. 34 p. { OPPTS 870.1300}

45312601 Green, C. ( 2001) Proxel TN: Single Exposure ( Nose only) Toxicity Study in the Rat: Final Report: Lab Project Number: 1573/ 9: 1573/ 9 D6154. Unpublished study prepared by Covance Laboratories Ltd. 47 p. { OPPTS 870.1300} 117 45410406 Moore, G. ( 2000) Acute Inhalation Toxicity Study in Rats Defined Limit Test: Troy EX663: Lab Project Number: 9115: TC0994. Unpublished study prepared by Product Safety Labs. 34 p. { OPPTS 870.1300}

45437103 Hilaski, R. ( 2001) An Acute Inhalation Toxicity Study of Rocima 607 in Rats: Lab Project Number: 285 059 A: 00RC 215. Unpublished study prepared by Rohm and Haas Company. 76 p. { OPPTS 870.1300}

45444709 Roy, B. ( 2001) Acute Inhalation Toxicity Study of Acticide MBS in Rats: Lab Project Number: 3091. Unpublished study prepared by JAI Research Foundation. 53 p. { OPPTS 870.1300}

45515804 Yingling, M. ( 2001) Acute Inhalation Generation Feasibility Study ( 1,2 Benzisothiazolin 3 One): Lab Project Number: 3864. Unpublished study prepared by Prom Chem Ltd. 11 p.

45553405 Merkel, D. ( 2001) Acute Inhalation Toxicity Test with Dantoserve: ( Rat): Lab Project Number: 10984. Unpublished study prepared by Product Safety Labs. 31 p. { OPPTS 870.1300}

45633901 Hilaski, R. ( 2001) Amendment to the Final Report an Acute Inhalation Toxicity Study of Rocima 607 in Rats: Lab Project Number: 285 059: 00RC 215: 00P 215. Unpublished study prepared by MPI Research, Inc. 127 p. { OPPTS 870.1300}

45793604 Merkel, D. ( 2002) Acute Inhalation Toxicity Study in Rats Defined LC50: Troy EX 680: Lab Project Number: 11078: TC1176: P330. Unpublished study prepared by Product Safety Labs. 45 p. { OPPTS 870.1300}

46287404 Tordo, L.; Rueb, B. ( 2004) Summary of the Acute Toxicity Characteristics of Acticide MBL 5515. Project Number: 042901/ LT/ 81. Unpublished study prepared by Thor GmbH. 5 p.

46448001 Roy, B. ( 2004) Statement of the Study Director on the Questions Raised by PSB Experts on the Following Study: Acute Inhalation Toxicity Study of Acticide MBL USREG in Rats ( Supplement to MRID 46287409). Project Number: 111504/ LT/ 81, 4589. Unpublished study prepared by: Jai Research Foundation. 6 p.

46603404 Tordo, L.; Rueb, B. ( 2005) Summary of the Acute Toxicity Charateristics of Acticide MBL. Project Number: 050404/ LT/ 81. Unpublished study prepared by Thor GmbH and Acti Chem Specailities, Inc. 5 p.

870.2400 ( 81 4) Primary eye irritation in rabbits MRID Citation Reference 118 133637 Swan, A. ( 1959) Toxicological Report: 1,2 Benzisothiazolone: ? Rab bits: Rats|: Report No. TR/ 197. ( Unpublished study received Nov 29, 1968 under 10182 1; prepared by Imperial Chemical Industries Ltd., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 026179 B)

133638 McElligott, T. ( 1966) Toxicological Report: Proxel PM Paste: ? Rab bits: Rats: Mice|: Report No. TR/ 490. ( Unpublished study re ceived Nov 29, 1968 under 10182 1; prepared by Imperial Chemical Industries Ltd., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 026179 C)

133680 Ball, S.; Phillips, J. ( 1976) Proxel XL: Oral Toxicity and Local Irritant Effects: Report No. CTL/ T/ 985. ( Unpublished study received Mar 6, 1979 under 10182 30; prepared by Imperial Chem ical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 238168 B)

134041 Surgikos, Inc. ( 1973) Proxel Press Paste: ? Summary of Toxicity Studies|. ( Unpublished study received Nov 12, 1972 under 7078 3; CDL: 050670 B)

134544 Swan, A. ( 1959) 1,2 Benzisothiazolone: Toxicological Report 197. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 B)

134545 Swan, A. ( 1959) 1,2 Benzisothiazolone ( Sodium Salt Dihydrate): Toxicological Report 223. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 C)

159675 Moreno, O.; Cerven, D.; Altenbach, E. ( 1985) Primary Eye Irritation Corrosion in Rabbits: Biochek 410: Project No. MB 85 7700D. Unpublished study prepared by MB Research Laboratories, Inc. 6 p.

42905102 Robinson, P. ( 1993) Proxel Press Paste: Eye Irritation to the Rabbit: Lab Project Number: CTL/ P/ 3961: FB4704. Unpublished study prepared by Zeneca Central Toxicology Lab. 24 p.

43229809 Shapiro, R. ( 1993) EPA Primary Eye Irritation: BP 1008 Industrial Preservative, Lot # 1: Lab Project Number: T 2445. Unpublished study prepared by Product Safety Labs. 21 p.

43489508 Robinson, P. ( 1994) Proxel BD20: Eye Irritation to the Rabbit: Lab Project Number: CTL/ P/ 4515: FB5013. Unpublished study prepared by Zeneca Central Toxicology Lab. 20 p.

43584004 Glaza, S. ( 1993) Primary Eye Irritation Study of XBINX in a Rabbit: Final Report: Lab Project Numbers: HWI 30601877: 30601877. Unpublished study prepared by Hazleton Wisconsin, Inc. 29 p.

43803803 Wnorowski, G. ( 1995) Nuosept Bit Technical: Primary Eye Irritation: ( Rabbits): Lab Project Number: 3860: P324. Unpublished study prepared by Product 119 Safety Labs. 24 p.

44290105 Cerven, D. ( 1997) Primary Eye Irritation/ Corrosion in Rabbits: Biochek 410: ( Final Report): Lab Project Number: MB 96 5466.04: 236 04 R/ A. Unpublished study prepared by MB Research Labs, Inc. 10 p.

44564001 Cerven, D. ( 1997) Primary Eye Irritation/ Corrosion in Rabbits: XBIX 17G: Lab Project Number: 236 04 R/ A: MB96 5631.04. Unpublished study prepared by MB Research Labs., Inc. 11 p.

44726908 Lees, D. ( 1998) Proxel TN: Eye Irritation Study in Rabbits: Lab Project Number: CTL/ P/ 5882: FB5647. Unpublished study prepared by Zeneca, Inc. 42 p.

45026006 Parcell, B. ( 1999) Nuosept 485 Eye Irritation to the Rabbit: Lab Project Number: DNN112. Unpublished study prepared by Huntingdon Life Science, Ltd. 14 p. { OPPTS 870.2400}

45100708 Moore, G. ( 2000) Primary Eye Irritation Study in Rabbits: Nipacide CBX: Lab Project Number: 8292: P324. Unpublished study prepared by Product Safety Labs. 15 p. { OPPTS 870.2400}

45410407 Moore, G. ( 2000) Primary Eye Irritation Toxicity Study in Rabbits: Troy EX663: Lab Project Number: 9116: TC0995. Unpublished study prepared by Product Safety Labs. 32 p. { OPPTS 870.2400}

45437104 Parno, J.; Craig, L.; Naudascher, P. ( 2001) Eye Irritation Study in Rabbits: Rocima 607: Lab Project Number: 00P 213: 00R 213. Unpublished study prepared by Rohm and Haas Company. 19 p. { OPPTS 870.2400}

45553406 Merkel, D. ( 2001) Primary Eye Irritation Test with Dantoserve: ( Rabbit): Lab Project Number: 10985. Unpublished study prepared by Product Safety Labs. 18 p. { OPPTS 870.2400}

45793605 Merkel, D. ( 2002) Primary Eye Irritation Study in Rabbits: Troy EX 680: Lab Project Number: 11079: TC1177: P324. Unpublished study prepared by Product Safety Labs. 27 p. { OPPTS 870.2400}

46603404 Tordo, L.; Rueb, B. ( 2005) Summary of the Acute Toxicity Charateristics of Acticide MBL. Project Number: 050404/ LT/ 81. Unpublished study prepared by Thor GmbH and Acti Chem Specailities, Inc. 5 p.

93053005 Parr Dobrzanski, R. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 00133680. Proxel XL ( BIT): Eye Irritation to the Rabbit: CTL Report NO. CTL/ T/ 985. Prepared by ICI Central Toxicology Laboratory. 6 p.

93053015 Ball, S. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 00133680. Proxel XL ( BIT): Eye Irritation to the Rabbit: CTL Report No. CTL/ T/ 985. Prepared by ICI Central Toxicology Laboratory. 14 p. 120 870.2500 ( 81 5) Primary dermal irritation MRID Citation Reference 133637 Swan, A. ( 1959) Toxicological Report: 1,2 Benzisothiazolone: ? Rab bits: Rats|: Report No. TR/ 197. ( Unpublished study received Nov 29, 1968 under 10182 1; prepared by Imperial Chemical Industries Ltd., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 026179 B)

133680 Ball, S.; Phillips, J. ( 1976) Proxel XL: Oral Toxicity and Local Irritant Effects: Report No. CTL/ T/ 985. ( Unpublished study received Mar 6, 1979 under 10182 30; prepared by Imperial Chem ical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 238168 B)

134041 Surgikos, Inc. ( 1973) Proxel Press Paste: ? Summary of Toxicity Studies|. ( Unpublished study received Nov 12, 1972 under 7078 3; CDL: 050670 B)

159674 Moreno, O.; Cerven, D.; Altenbach, E. ( 1985) Primary Dermal Irrita tion in Rabbits: Biochek 410: Project No. MB 85 7700C. Unpub lished study prepared by MB Research Laboratories, Inc. 7 p.

42905101 Robinson, P. ( 1993) Proxel Press Paste: Skin Irritation to the Rabbit: Lab Project Number: CTL/ P/ 3958: EB4147. Unpublished study prepared by Zeneca Central Toxicology Lab. 20 p.

43229810 Shapiro, R. ( 1993) EPA Primary Dermal Irritation: BP 1008 Industrial Preservative, Lot # 1: Lab Project Number: T 2446: P326: E30615 6. Unpublished study prepared by Product Safety Labs. 16 p.

43484502 Leah, A. ( 1994) First Revision to PROXEL BD: Skin Corrosivity to the Rabbit: Lab Project Number: CTL/ P/ 2217: EB1832. Unpublished study prepared by Zeneca Central Toxicology Lab. 20 p.

43489509 Robinson, P. ( 1994) Proxel BD20: Skin Irritation to the Rabbit: Lab Project Number: CTL/ P/ 4514: EB4324. Unpublished study prepared by Zeneca Central Toxicology Lab. 21 p.

43584005 Glaza, S. ( 1993) Primary Dermal Irritation Study of XBINX in Rabbits: Final Report: Lab Project Numbers: HWI 30601876: 30601876. Unpublished study prepared by Hazleton Wisconsin, Inc. 27 p.

43596009 Robinson, P. ( 1994) PROXEL XL2: Skin Irritation to the Rabbit: Lab Project Numbers: CTL/ P/ 4518: EB4326. Unpublished study prepared by Zeneca Central Toxicology Lab. 22 p.

43803804 Wnorowski, G. ( 1995) Nuosept Bit Technical: Primary Skin Irritation: ( Rabbits): Lab Project Number: 3861: P326. Unpublished study prepared by Product Safety Labs. 16 p. 121 43803906 Wnorowski, G. ( 1995) Primary Skin Irritation: Nuosept 495: ( Rabbits): Lab Project Number: 3847. Unpublished study prepared by Product Safety Labs. 16 p.

44290104 Kieffer, L. ( 1997) Primary Dermal Irritation in Rabbits: Biochek 410: ( Final Report): Lab Project Number: MB 96 5466.03: 166 05. Unpublished study prepared by MB Research Labs, Inc. 10 p.

44564002 Kieffer, L. ( 1997) Primary Dermal Irritation in Rabbits: XBINX 17G: Lab Project Number: MB96 5631.03: 166 05 R/ A. Unpublished study prepared by MB Research Labs., Inc. 11 p.

44726909 Lees, D. ( 1998) Proxel TN: Skin Irritation Study in Rabbits: Lab Project Number: EB4723: CTL/ P/ 5881. Unpublished study prepared by Zeneca, Inc. 21 p.

44966001 Haynes, G.; Middleton, J. ( 1995) First Revision to Proxel GXL: Skin Corrosivity Study ( in Rabbits): Lab Project Number: CTL/ C/ 782: EB0430. Unpublished study prepared by Toxicol Laboratories Limited. 29 p.

45026007 Parcell, B. ( 1999) Nuosept 485 Skin Irritation to the Rabbit: Lab Project Number: DNN113. Unpublished study prepared by Huntingdon Life Science, Ltd. 14 p. { OPPTS 870.2500}

45100709 Moore, G. ( 2000) Primary Skin Irritation Study in Rabbits: Nipacide CBX: Lab Project Number: 8293: P326. Unpublished study prepared by Product Safety Labs. 15 p. { OPPTS 870.2500}

45236806 Wnorowski, G. ( 1998) Primary Skin Irritation ( in Rabbits): Mergal K10N: Lab Project Number: 6418: TCO852: P326. Unpublished study prepared by Product Safety Labs. 28 p.

45410408 Moore, G. ( 2000) Primary Skin Irritation Toxicity Study in Rabbits: Troy EX663: Lab Project Number: 9117: TC0996. Unpublished study prepared by Product Safety Labs. 26 p. { OPPTS 870.2500}

45437105 Parno, J.; Craig, L.; Naudascher, P. ( 2000) Skin Irritation Study in Rabbits: Rocima 607: Lab Project Number: 00P 212: 00R 212. Unpublished study prepared by Rohm and Haas Company. 17 p.

45444710 Rana, M. ( 2001) Acute Dermal Irritation Study of Acticide MBS in Rabbits: Lab Project Number: 3090. Unpublished study prepared by JAI Research Foundation. 34 p. { OPPTS 870.2500}

45553407 Merkel, D. ( 2001) Primary Skin Irritation Test with Dantoserve: ( Rabbit): Lab Project Number: 1098. Unpublished study prepared by Product Safety Labs. 16 p. { OPPTS 870.2500}

45793606 Merkel, D. ( 2002) Primary Skin Irritation Study in Rabbits: Troy EX 680: Lab Project Number: 11080: TC1178: P326. Unpublished study prepared by Product 122 Safety Labs. 25 p. { OPPTS 870.2500}

46287404 Tordo, L.; Rueb, B. ( 2004) Summary of the Acute Toxicity Characteristics of Acticide MBL 5515. Project Number: 042901/ LT/ 81. Unpublished study prepared by Thor GmbH. 5 p.

46603404 Tordo, L.; Rueb, B. ( 2005) Summary of the Acute Toxicity Charateristics of Acticide MBL. Project Number: 050404/ LT/ 81. Unpublished study prepared by Thor GmbH and Acti Chem Specailities, Inc. 5 p.

93053006 Parr Dobrzanski, R. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 00133680. Proxel XL ( BIT): Skin Irritation to the Rat: CTL Report No. CTL/ T/ 985. Prepared by ICI Central Toxicology Laboratory. 6 p.

93053016 Ball, S. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 00133680. Proxel XL ( BIT): Skin Irritation to the Rat: CTL Report No. CTL/ T/ 985. Prepared by ICI Central Toxicology Laboratory. 14 p.

870.2600 ( 81 6) Dermal sensitization MRID Citation Reference 41750001 Botham, P.; Robinson, P. ( 1990) Benzisothiazolin 3 one: Skin Sensi tization to the Guinea Pig: Lab Project Number: CTL/ P/ 3101: GG3802: GG3721. Unpublished study prepared by ICI Central Toxi cology Lab. 28 p.

42429106 Shapiro, R. ( 1992) EPA Guinea Pig Sensitization ( Buehler): IL 2529: Lab Project Number: T 1123. Unpublished study prepared by Product Safety Labs. 29 p.

42858103 Burt, M. ( 1993) Benzisothiazolin 3 One: Skin Sensitization to the Guinea Pig: Addendum: Lab Project Number: CTL/ P/ 3101. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

43229811 Shapiro, R. ( 1993) EPA Guinea Pig Sensitization Test ( Buehler): BP 1008 Industrial Preservative, Lot # 1: Lab Project Number: T 2448: P328: E30615 6. Unpublished study prepared by Product Safety Labs. 28 p.

43489510 Robinson, P. ( 1994) Proxel BD20: Skin Sensitization to the Guinea Pig: Lab Project Number: CTL/ P/ 4516: GG6226. Unpublished study prepared by Zeneca Central Toxicology Lab. 31 p.

43584006 Glaza, S. ( 1993) Dermal Sensitization Study of XBINX in Guinea Pigs Closed Patch Technique: Final Report: Lab Project Numbers: HWI 30601878: 30601878. Unpublished study prepared by Hazleton Wisconsin, Inc. 38 p.

43596010 Robinson, P. ( 1994) PROXEL XL2: Skin Sensitisation to the Guinea Pig: Lab Project Numbers: CTL/ P/ 4519: GG6269. Unpublished study prepared by 123 Zeneca Central Toxicology Lab. 30 p.

43803805 Wnorowski, G. ( 1995) Nuosept Bit Technical: Dermal Sensitization Test Buehler Method: ( Guinea Pigs): Lab Project Number: 3863: P328. Unpublished study prepared by Product Safety Labs. 24 p.

43803907 Wnorowski, G. ( 1995) Dermal Sensitization Test Buehler Method: Nuosept 495: ( Guinea Pigs): Lab Project Number: 3849. Unpublished study prepared by Product Safety Labs. 24 p.

44726910 Lees, D. ( 1998) Proxel TN: Skin Sensitisation Study in Guinea Pigs: Lab Project Number: CTL/ P/ 5883: GG7069. Unpublished study prepared by Zeneca, Inc. 36 p.

44959802 Bugg, L. ( 1995) Proxel GXL: Skin Sensitisation to the Guinea Pig: Lab Project Number: CTL/ P/ 4634: GG6388. Unpublished study prepared by Zeneca Central Toxicology Labs. 27 p.

45026008 Coleman, D. ( 1999) Nuosept 485 Skin Sensitization to the Guinea Pig ( Buehler Method 3 Inductions): Lab Project Number: DNN114. Unpublished study prepared by Huntingdon Life Science, Ltd. 28 p. { OPPTS 870.2600}

45236807 Wnorowski, G. ( 1998) Dermal Sensitization Test Buehler Method ( in Guinea Pigs): Mergal K10N: Lab Project Number: 6419: TCO853: P328. Unpublished study prepared by Product Safety Labs. 37 p.

45410409 Moore, G. ( 2000) Dermal Sensitization Toxicity Study in Guinea Pigs ( Buehler Method): Troy EX663: Lab Project Number: 9118: TC0997. Unpublished study prepared by Product Safety Labs. 37 p. { OPPTS 870.2600}

45437106 Parno, J.; Anderson, D.; Lutz, M. ( 2001) Delayed Contact Hypersensitivity Study in Guinea Pigs: Rocima 607: Lab Project Number: 00P 214: 00R 214. Unpublished study prepared by Rohm and Haas Company. 54 p. { OPPTS 870.2600}

45489402 Stahl, J. ( 2000) Acute Skin Sensitization Study of Test Item Acticide MBS in Guinea Pigs by Magnusson Kligman Method: Lab Project Number: 99/ 431 104 T. Unpublished study prepared by Toxicological Research Centre Ltd. 64 p. { OPPTS 870.2600}

45799802 Merkel, D. ( 2002) Dermal Sensitization Study in Guinea Pigs ( Magnusson Kligman Method): Troy EX 680: Lab Project Number: 11081: TC1179: P329. Unpublished study prepared by Product Safety Labs. 40 p. { OPPTS 870.2600}

46287404 Tordo, L.; Rueb, B. ( 2004) Summary of the Acute Toxicity Characteristics of Acticide MBL 5515. Project Number: 042901/ LT/ 81. Unpublished study prepared by Thor GmbH. 5 p.

46603404 Tordo, L.; Rueb, B. ( 2005) Summary of the Acute Toxicity Charateristics of Acticide MBL. Project Number: 050404/ LT/ 81. Unpublished study prepared by 124 Thor GmbH and Acti Chem Specailities, Inc. 5 p.

870.3100/ 3150 ( 82 1) Subchronic Oral Toxicity: 90 Day Study MRID Citation Reference 134546 Conning, D. ( 19??) Benzisothiazolone: Toxicological Report 553. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 D)

134547 Kinch, D. ( 1969) Antibacterial DS4547: Toxicological Report 697. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 E)

41910401 Whiles, A. ( 1990) Proxel Press Paste: 90 Day Feeding Study in Rats: Lab Project Number: CTL/ P/ 3138: PRO798. Unpublished study pre pared by ICI Central Toxicology Lab/ Alderley Park, UK. 366 p.

42205701 Allen, S. ( 1991) Proxel Press Paste: 90 Day Oral Toxicity Study in Dogs: Lab Project Number: CTL/ P/ 3399: PD0830. Unpublished study prepared by ICI Central Toxicology Lab. 326 p.

46346201 Kumar, D. ( 2002) Repeated Dose ( 90 Day) Oral Toxicity Study By Gavage With Promex Bit in Wistar Rats: Final Report. Project Number: 3287/ 01, TOXI/ 3287/ 01, 072/ 1/ PBP/ 90/ OGR. Unpublished study prepared by Rallis Research Centre, Rallis India. 211 p.

870.3250 ( 82 3) 90 day dermal rodent MRID Citation Reference 134544 Swan, A. ( 1959) 1,2 Benzisothiazolone: Toxicological Report 197. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 B)

134546 Conning, D. ( 19??) Benzisothiazolone: Toxicological Report 553. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 D)

45184601 Cerven, D. ( 2000) 90 Day Repeated Dose Dermal Toxicity Study in Rats: 125 XBINX 88: Lab Project Number: MB 99 7974 02: 1155. Unpublished study prepared by MB Research Laboratories. 150 p.

870.3700 ( 83 3) Teratogenicity  2 Species MRID Citation Reference 40961201 Pigott, G. ( 1988) Proxel Press Paste: Teratogenicity Study in the Rat: Rept. No. CTL/ P/ 2297. Unpublished study prepared by Impe rial Chemical Industries Ltd. 368 p.

42858104 Burt, M. ( 1993) Proxel Press Paste: Teratogenicity Study in the Rat: Addendum: Lab Project Number: CTL/ P/ 2297. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

43663008 Henwood, S. ( 1994) Developmental Toxicity Study with Xbinx in Rats: Final Report: Lab Project Number: HWI 6533 100: TP3399. Unpublished study prepared by Hazleton Wisconsin, Inc. 213 p.

93053007 Guttmann, E. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 40961201. BIT ( Proxel) Press Paste: Teratogenicity Study in the Rat: CTL Report No.: CTL/ P/ 2297; CTL Study No: RR0396. Prepared by ICI Central Toxicology Laboratory. 7 p.

93053017 Pigott, G. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 40961201. BIT ( Proxel) Press Paste: Teratogenicity Study in the Rat: CTL Report No. CTL/ P/ 2297; CTL Study No. RR0396. Prepared by ICI Central Toxicology Lab. 371 p.

870.5265/ 5300/ 5395 ( 84 2) Intreraction with Gonadal DNA MRID Citation Reference 41022103 Cross, M. ( 1988) Proxell Press Paste: Assessment of Mutagenic Potential Using L5178Y Lymphoma Cells: Report No. CTL/ P/ 2215. Unpublished study prepared by Imperial Chemical Industries Ltd. 44 p.

41022104 Sheldon, T.; Richardson, C.; Randall, V.; et al. ( 1988) Proxel Press Paste: An Evaluation in the Mouse Micronucleus Test: Report No. CTL/ P/ 2113. Unpublished study prepared by Imperial Chemical Industries Ltd. 36 p.

41022105 Trueman, R. ( 1988) Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocytes Cul tures: Report No. CTL/ P/ 2208. Unpublished study prepared by Imperial Chemical Industries Ltd. 126 40 p.

41687104 Callander, R. ( 1989) Proxel Press Paste: An Evaluation in the Sal monella Mutation Assay: Lab Project Number: CTL/ P/ 2369. Unpub lished study prepared by ICI Central Toxicology Laboratory. 46 p.

42858105 Burt, M. ( 1993) Proxel Press Paste: Assessment of Mutagenic Potential Using L5178Y Mouse Lymphoma Cells: Addendum: Lab Project Number: CTL/ P/ 2215. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

42858106 Burt, M. ( 1993) Proxel Press Paste: An Evaluation in the Mouse Micronucleus Test: Addendum: Lab Project Number: CTL/ P/ 2113. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

42858107 Burt, M. ( 1993) Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocyte Cultures: Addendum: Lab Project Number: CTL/ P/ 2208. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

43584007 Lawlor, T. ( 1994) Mutagenicity Test on 1,2 Benzisothiazolin 3 one ( XBINX) in the Salmonella/ Mammalian Microsome Reverse Mutation Assay ( Ames Test): Final Report: Lab Project Number: 15693 0 401: 401. Unpublished study prepared by Hazleton Washington, Inc. 48 p.

43584008 Murli, H. ( 1993) Mutagenicity Test on 1,2 Benzisothiazolin 3 one ( XBINX) In vivo Mammalian Micronucleus Assay: Final Report: Lab Project Numbers: 15693 0 455: 20996: 455. Unpublished study prepared by Hazleton Washington, Inc. 22 p.

43584009 Cifone, M. ( 1994) Mutagenicity Test on 1,2 Benzisothiazolin 3 one ( XBINX) in the L5178Y TK +/ Mouse Lymphoma Foward Mutation Assay With a Confirmatory Assay: Revised Final Report: Lab Project Numbers: 15693 0 431R: 431R: 20989. Unpublished study prepared by Hazleton Washington, Inc. 55 p.

45534603 Kelly, J. ( 1996) Bacterial Reverse Mutation Test: Promex: Final Report: Lab Project Number: M/ AMES/ 42441. Unpublished study prepared by Quintiles England Limited. 49 p.

45770301 Howe, J. ( 2002) Proxel Press Paste ( BIT): Measurement of Unscheduled DNA Synthesis in Rat Liver Using an in vivo/ in vitro Procedure: Amended Final Report: Lab Project Number: 1803/ 21: 1803/ 21 D6173. Unpublished study prepared by Covance Laboratories Ltd. 44 p.

93053008 Callander, R. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41022103. Proxel Press Paste: Assessment of Mutagenic Potential Using L5178Y Mouse Lymphoma Cells: CTL Report No. CTL/ P/ 2215: CTL Study No. VV0076. Prepared by ICI Central Toxicology Laboratory. 6 p. 127 93053009 Mackay, J. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41022104. Proxel Press Paste: An Evaluation in the Mouse Micronucleus Test: CTL Report No. CTL/ P/ 2113; CTL Study No. SM0290. Prepared by ICI Central Toxicology Laboratory. 7 p.

93053010 Kennelly, J. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41022105. Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocyte Cultures: CTL Report No. CTL/ P/ 2208; CTL Study No. SV0309. Prepared by ICI Central Toxicology Laboratory. 7 p.

93053018 Cross, M. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 41022103. Proxel Press Paste: Assessment of Mutagenic Potential Using L5178Y Mouse Lymphoma Cells: CTL Study No. VV0076; CTL Report No. CTL/ P/ 2215. Prepared by ICI Central Toxicology Lab. 43 p.

93053019 Sheldon, R.; Richardson, C.; Randall, V. et al. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 41022104. Proxel Press Paste: An Evaluation in the Mouse Micronucleus Test: CTL Study No. SM0290; CTL Report No. CTL/ P/ 2113. Prepared by ICI Central Toxicology Lab. 34 p.

93053020 Trueman, R. ( 1990) ICI Americas Inc. Phase 3 Reformat of MRID 41022105. Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocyte Cultures: CTL Study No. SV0309; CTL Report No: CTL/ P/ 2208. Prepared by ICI Central Toxicology Lab. 39 p.

870.5550 ( 84 4) Other Genotoxic Effects MRID Citation Reference 42858107 Burt, M. ( 1993) Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocyte Cultures: Addendum: Lab Project Number: CTL/ P/ 2208. Unpublished study prepared by Zeneca Central Toxicology Lab. 4 p.

41022105 Trueman, R. ( 1988) Proxel Press Paste: Assessment for the Induction of Unscheduled DNA Synthesis in Primary Rat Hepatocytes Cul tures: Report No. CTL/ P/ 2208. Unpublished study prepared by Imperial Chemical Industries Ltd. 40 p.

870.7485 ( 85 1) Metabolism and Pharmacokinetics MRID Citation Reference 45124901 Conning, D. ( 1972) ( Inert Ingredient): Excretion and Tissue Retention in the Rat: Lab Project Number: HO/ IH/ P/ 3. Unpublished study prepared by Imperial 128 Hygiene Research Laboratories. 10 p.

860.1100 ( 171 2) Chemical Identity MRID Citation Reference 41710601 Evans, K. ( 1990) Proxel Press Paste: Chemical Characterisation of Material: Representative of Huddersfield Works Manufacture: Lab Project Number: 144. Unpublished study prepared by ICI Colours and Fine Chemicals. 84 p.

835.2120 ( 161 1) Hydrolysis MRID Citation Reference 41199101 Field, B. ( 1989) 1,2 Benzisothiazolin 3 one: Hydrolysis Study, Report D96901B. Unpublished study prepared by Imperial Chemical Industries Ltd. 10 p.

44182101 Cincinnati Specialties, Inc. ( 1996) Hydrolysis Study of 1,2 Benzisothiazoline 3( 2H) One: Lab Project Number: 19 IP 091096. Unpublished study. 21 p.

44671501 Pearson, R. ( 1998) Response to EPA Review on Hydrolysis Study of 1,2 Benzisothiazol 3( 2H) One ( MRID 441821 01). Unpublished study prepared by Cincinnati Specialties, Inc. 12 p.

45929801 Geffke, T. ( 2002) Acticide BIT: Hydrolysis as a Function of pH: 1st Amendment to Report: Lab Project Number: 001025TS: CHP79841: CPH7984. Unpublished study prepared by Dr. U. Noack Laboratorium fur Angewandte Biologie. 41 p.

45929802 Geffke, T. ( 2002) Acticide BIT: Hydrolysis as a Function of pH ( 1.2): Lab Project Number: 001025TS: CPX79841: CPX7984. Unpublished study prepared by Dr. U. Noack Laboratorium fur Angewandte Biologie. 35 p.

93053011 Burt, M. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41199101. 1,2 Benzisothiazolin 3 One Hydrolysis Study. Prepared by ICI Colours and Fine Chemicals. 11 p.

835.4100 ( 162 1) Aerobic soil metabolism MRID Citation Reference 41199102 Roberts, G. ( 1989) 1,2, Benzisothiazolin 3 one: Aerobic Degradation in Soil: Study ID: R048/ D. Unpublished study prepared by Imperial Chemical Industries 129 PLC. 35 p.

41199103 Powell, B. ( 1989) 1,2 Benzisothiazolin 3 one ( BIT): Identification of Metabolites Formed by Aerobic Degradation in Soil, Report No. D97198B. Unpublished study prepared by Imperial Chemical Indus tries Ltd. 48 p.

93053012 Burt, M. ( 1990) ICI Americas Inc. Phase 3 Summary of MRID 41199102 and Related MRIDs 41199103. 1,2 Benzisothiazolin 3 One: Aerobic Degradation in Soil. Prepared by Imperial Chemical Industries PLC. 18 p.

835.1230/ 1240 ( 163 1) Leach/ adsorp/ desorption MRID Citation Reference 41687102 Wilkes, L. ( 1989) Adsorption/ Desorption Study for 1,2 Benzisothia zolin 3 One: Lab Project Number: ADC/ PROJECT/# 1129. Unpublished study prepared by Analytical Development Corp. 127 p.

860.1400 ( 171 4C) Magnitude of the Residue [ by commodity]

MRID Citation Reference 103900 Fink, R.; Guyton, C. ( 1973) Final Report: Tissue Residue Study Bluegill Sunfish...: ? Benzisothiazolone ( Analytical); Benziso thiazolone C14 ( Radioactive)|: Project No. 106 133. ( Unpub lished study received Aug 29, 1973 under 10182 3; prepared by Environmental Sciences Corp., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 008767 C)

870.7600 ( 85 3) Dermal penetration MRID Citation Reference 46327901 O'Connor, J. ( 1999) Nipacide Bit: Preliminary Study to Assess the Absorption of Nipacide Bit from the Skin and Gastrointestinal Tract in the Male Rat. Project Number: NLL060/ 970078, 970078. Unpublished study prepared by Huntington. 181 p.

Non Guideline Study MRID Citation Reference 130 24229 Schuder, D. L.; Niemczyk, H. D.; Reinert, J. A.; et al. ( 1976) Turf Pests. ( Unpublished study including published data, received Jan 24, 1977 under 9198 36; prepared in cooperation with Purdue Univ., Dept. of Entomology and others, submitted by Anderson Lawn Fertilizer, Div. of Free Flow Fertilizer Co., Maumee, Ohio; CDL: 227632 A)

46486 ICI Americas, Incorporated ( 19??) ? Toxicity of Proxel to Rainbow Trout and Various Fish|. ( Unpublished study received Aug 18, 1980 under 10182 3; CDL: 243274 B)

46487 ICI Americas, Incorporated ( 19??) Miscellaneous Environmental Test. ( Incomplete; unpublished study received Aug 18, 1980 under 10182 3; CDL: 243274 C)

133636 ICI Americas, Inc. ( 19??) ? Proxel PM Paste: Efficacy Data: Paints|. ( Compilation; unpublished study received Nov 29, 1968 under 10182 1; CDL: 026179 A)

133639 Boardman, G. ( 1969) Proxel PM Paste USDA Application: ? Bacterio logical Tests: Paints|. ( Unpublished study received May 5, 1969 under 10182 1; submitted by ICI Americas, Inc., Wilmington, DE; CDL: 026180 A)

133667 Fink, R.; Guyton, C. ( 1973) Tissue Residue Study Bluegill Sunfish ( Lepomis macrochirus) ? Using| Benzisothiazolone ( Analytical) ? and| Benzisothiazolone C14 ( Radioactive): Project No. 106 133. Final rept. ( Unpublished study received Aug 29, 1973 under 10182 3; prepared by Hazleton Laboratories, Inc., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 131696 A)

133877 Palmer, R.; Jones, B. ( 1976) 1,2 Benzisothiazolin 3 one: Biodegra dation in Aqueous Systems: Report No. HO/ IH/ P/ 94. ( Unpublished study received Mar 23, 1979 under 10182 3; submitted by ICI Americas, Inc., Wilmington, DE; CDL: 238545 B)

134038 ICI Americas, Inc. ( 1971) ? Efficacy: Proxel CRL|. ( Compilation; unpublished study received Jan 10, 1972 under 10182 3; CDL: 016020 F)

134043 Majors, P.; Ede, M. ( 1972) Repeated Insult Patch Test of Proxel CRL ( 250 PPM): ? Human Subjects|: Report 72 462 71. ( Unpublished study received Aug 22, 1973 under 10182 3; prepared by Hill Top Research, Inc., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 050749 A)

134044 Majors, P.; Ede, M. ( 1972) Repeated Insult Patch Test of Proxel CRL ( 500 PPM): ? Human Subjects|: Report 72 469 71. ( Unpublished study received Aug 22, 1973 under 10182 3; prepared by Hill Top Research, Inc., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 050749 B)

134056 Imperial Chemical Industries Ltd. ( 1961) ? Efficacy Studies of Benzisothiazolone and Its Safety|. ( Compilation; unpublished study received 131 Feb 23, 1971 under 0H2547; CDL: 221692 B)

134057 Cartmell, A. ( 1970) Letter sent to L. Ter Bush dated Sep 28, 1970 ? Benzisothiazolone: Food additive data|. ( Unpublished study received Feb 23, 1971 under 10182 1; submitted by ICI Americas, Inc., Wilmington, DE; CDL: 221693 A)

134548 Clark, D. ( 1970) Irritant Properties of Antibacterial DS4547 ( Prox el PL): Report HO/ IH/ T740. ( Unpublished study received Feb 23, 1971 under 10182 3; prepared by Imperial Chemical Industries, Ltd., Eng., submitted by ICI Americas, Inc., Wilmington, DE; CDL: 004863 F)

40157600 Chevron Chemical Co. ( 1987) Submission of Product Chemistry Data To Support the Registration of Ortho Mite Insecticidal Soap. Transmittal of 1 study.

40650900 ICI Americas Inc. ( 1988) Submission of Chemistry Data in Support of Proxel GXL. Transmittal of 1 study.

40691100 Troy Chemical Corp. ( 1988) Application for Pesticide Registration: Troysan Polyphase RG 1. Transmittal of 1 study.

40950600 Nipa Laboratories, Inc. ( 1988) Submission of Data To Support the Application for Nipacide Registration: Product Chemistry Data. Transmittal of 1 study.

40950700 Nipa Laboratories, Inc. ( 1988) Submission of Data To Support the Registration of Nipacide X: Product Chemistry Data. Transmittal of 1 study.

40961200 ICI Americas Inc. ( 1989) Submission of Toxicology Data to Support the Registration for Proxel DL Microbiostat. Transmittal of 1 study.

40989200 Nipa Laboratories, Inc. ( 1988) Submission of Toxicity Data to Sup port the Registration for Nipacide X. Transmittal of 1 study.

40991300 ICI Americas, Inc. ( 1988) Submission of Toxicity Data to Support the Continued Registration of Products Containing 1,2 Benziso thiazolin 3 one. Transmittal of 1 study.

40994500 ICI Americas Inc. ( 1988) Submission of Data To Support the Applica tion for Registration of Proxel DL: Product Chemistry Data. Transmittal of 1 study.

41022100 ICI Americas Inc. ( 1988) Submission of Data To Support Registration of Proxell Press Paste: Toxicology Data. Transmittal of 5 stu dies.

41199100 ICI Americas Inc. ( 1989) Submission of Data To Support Registration of Proxel DL Microbiostat: Environmental Fate Studies. Trans mittal of 3 studies.

41635400 ICI Americas Inc. ( 1990) Submission of Data To Support the Applica tion for Registration of Proxel GXL Industrial Microbiostat: Product Chemistry Study. Transmittal of 1 study.

41635500 ICI Americas Inc. ( 1990) Submission of Data To Support the Application for 132 Registration of Proxel DL Industrial Microbio stat: Product Chemistry Study. Transmittal of 1 study.

41635600 ICI Americas Inc. ( 1990) Submission of Data To Support the Application for Registration of Proxel BD Industrial Micro biocide: Product Chemistry Study. Transmittal of 1 study.

41687100 ICI Americas, Inc. ( 1990) Submission of Product Chemistry, Toxi city, and Environmental Fate Data to Support the Reregistration of Proxel Press Paste. Transmittal of 4 Studies.

41710600 ICI Americas, Inc. ( 1990) Submission of Chemistry Data in Support of Proxel Reregistration. Transmittal of 1 study.

41732000 ICI America Inc. ( 1990) Submission of Toxicological Effects Data In Support of Benzisothiazolin 3 one Reregistration. Transmit tal of 1 Study.

41750000 ICI Americas Inc. ( 1991) Submission of Data To Support Reregistra tion of Benzisothiazolin 3 One: Toxicology Study. Transmittal of 1 study.

41893900 ICI Americas Inc. ( 1991) Submission of Data to Support the Regist ration of Proxel BD: Product Chemistry Data. Transmittal of 1 Study.

41902700 ICI Americas, Inc. ( 1991) Submission of Data to Support the Regist ration of Proxel DL: Procduct Chemistry Data. Transmittal of 1 Study.

41910400 ICI Americas Inc. ( 1991) Submission of toxicity data to support the reregistration of Proxel Press Paste ( Benzisothiazolin 3 one). Transmittal of 1 study.

41927500 ICI Americas, Inc. ( 1991) Submission of product chemistry data in support of reregistration of benzisothiazolin 3 one. Transmit tal of 1 study.

41954400 ICI Americas Inc. ( 1991) Submission of Data to Support the Reregistration of Benzisothiazolin 3 one: Product Chemistry Data. Transmittal of 1 Study.

42196200 ICI Americas Inc. ( 1991) Submission of Acute Inhalation Toxicity study in support of registration of Proxel GXL Industrial Micro biostat. Transmittal of 1 study.

42205700 ICI Americas, Inc. ( 1992) Submission of toxicity data in support of reregistration of Proxel Press Paste. Transmittal of 2 studies.

42205702 Allen, S. ( 1991) Proxel Press Paste: 6 Week Preliminary Study in Dogs: Lab Project Number: CTL/ L/ 3933: PD0786. Unpublished study prepared by ICI Central Toxicology Lab. 8 p.

42398100 ICI Specialty Chemicals ( 1992) Submission of product chemistry data in support of the reregistration of Benzisothiazolin 3 one. Transmittal of 1 study.

42398101 Guyan, S. ( 1992) Final Report of the Determination of Polychlorinated Dibenzo p dioxins and Dibenzofurans in Proxel Press Paste: Lab Project 133 Number: 16510. Unpublished study prepared by Triangle Laboratories, Inc. 51 p.

42429100 ICI Americas Inc. ( Specialty Chem.) ( 1992) Submission of product chemistry and toxicity data to support the registration of Proxel MX Preservative ( IL 2529). Transmittal of 6 studies.

42515100 ICI Americas, Inc. ( 1992) Submission of product chemistry data in support of the reregistration of Benzisothiazolin 3 one. Transmittal of 1 study.

42524300 ICI Specialties ( 1992) Submission of product chemistry data in support of the registration of Proxel Press Paste. Transmittal of 1 study.

42555600 ICI Americas Inc. ( 1992) Submission of toxicity data in support of reregistration for Benzisothiazolin 3 one. Transmittal of 1 study.

42569800 ICI Americas Inc. ( 1992) Submission of product chemistry data in support of registration for Proxel MX Preservative. Transmittal of 3 studies.

42650800 Zeneca ( 1993) Submission of product chemistry data in support of the reregistration for Benzisothiazolin 3 one. Transmittal of 1 study.

42780200 Nipa Laboratories, Inc. ( 1993) Submission of product chemistry data in support of the registration for NIPA BIT Press Paste. Transmittal of 4 studies.

42858100 Zeneca Biocides ( 1993) Submission of supplemental toxicity data in support of phase 3 reregistration for Proxel Press Paste ( Benzisothiazolin 3 One). Transmittal of 7 studies.

42905100 Zeneca Inc. ( 1993) Submission of Toxicity Data for Proxel Press Paste in Support of Reregistration. Transmittal of 3 Studies.

42908200 Zeneca Inc. ( 1993) Submission of Product Chemistry Data in Support of Reregistration of Benzisothiazolin 3 one. Transmittal of 1 study.

42943400 ZENECA Inc. ( 1993) Submission of Product Chemistry Data for Benzisothiazolin 3 one in Support of Reregistration. Transmittal of 1 Study.

42945000 Zeneca Biocides ( 1993) Submission of Toxicology Data in Support of the Reregistration of Benzisothiazolin 3 one. Transmittal of 1 1 study.

42949000 Zeneca Inc. ( 1993) Submission of Acute Toxicology Data in Support of Benzisothiazolin 3 one Reregistration. Transmittal of 2 Studies.

42952400 Zeneca Inc. ( 1993) Submission of Toxicity Data for Benzisothiazolin 3 one in Support of Reregistration. Transmittal of 1 study.

42961100 ZENECA Inc. ( 1993) Submission of Product Chemistry Data in Response to EPA Questions of Studies Submitted to Support Reregistration of Benzisothiazolin 3 one. Transmittal of 1 Study.

42967100 Huls America Inc. ( 1993) Submission of Product Chemistry Data for NUOSEPT 134 495 Preservative in Support of a Me Too Registration. Transmittal of 2 Studies.

43229800 ZENECA Inc. ( 1994) Submission of Product Chemistry Data and Toxicity Data for PARADYME Preservative in Support of Registration. Transmittal of 11 studies.

43354200 Zeneca, Inc. ( 1994) Submission of Product Chemistry Data in Support of Registration Amendment for Proxel GXL Industrial Microbiostat. Transmittal of 1 Study.

43398200 Zeneca Inc. ( 1994) Submittal of Product Chemistry Data in Support of Registration for Paradyme Preservative. Transmittal of 1 study.

43424800 Zeneca, Inc. ( 1994) Submission of Manufacturing Process Data in Support of Registration Amendment for Proxel MX Preservative ( Reputain). Submission of 1 Study.

43484500 Zeneca, Inc. ( 1994) Submission of Toxicity Data in Support of Application for Label Amendment for PROXEL BD Industrial Microbiocide. Transmittal of 2 Studies.

43489500 Zeneca, Inc. ( 1994) Submission of Product Chemistry and Toxicity Data in Support of the Registration of PROXEL BD20 Industrial Microbiostat. Transmittal of 10 Studies.

43536300 ZENECA Biocides ( 1995) Submission of product chemistry data in support of registration of Proxel MX Preservative. Transmittal of 1 study.

43542900 Zeneca, Inc. ( 1995) Submission of Product Chemistry Data in Support of the Registration of PARADYME Preservative. Transmittal of 2 Studies.

43584000 PMC Specialties Group ( 1995) Submission of Product Chemistry and Toxicity Data in Support of the Registration of the 1,2 Benzoisothiazol 3( 2H) one Containing Product XBINX. Transmittal of 9 Studies.

43585600 Zeneca, Inc. ( 1995) Submission of Toxicity Data in Support of a Registration Amendment for Proxel MX. Transmittal of 1 Study.

43586000 Zeneca Biocides ( 1995) Submission of Product Chemistry and Toxicity Data in Support of Application for Registration of Purified Proxel Press Paste. Transmittal of 5 Studies.

43586005 Burt, M. ( 1995) Purified Proxel Press Paste: Assessment of Toxicity and Environmental Effects: Lab Project Number: P4 A. Unpublished study prepared by Zeneca, Inc. 5 p.

43596000 Zeneca Biocides ( 1995) Submission of Product Chemistry and Toxicity Data in Support of the Registration of PROXEL XL 2. Transmittal of 10 Studies.

43607600 Steptoe & Johnson ( 1995) Submission of product chemistry data in support of registration of Nuosept 495 Preservative. Transmittal of 1 study. 135 43663000 PMC Specialties Group, Inc. ( 1995) Submission of Product Chemistry and Toxicology Data in Support of Application for Registration of XBINX. Transmittal of 8 Studies.

43674600 Zeneca, Inc. ( 1995) Submission of Product Chemistry Data in Support of the Application for Registration of Purified Proxel Press Paste. Transmittal of 1 Study.

43724100 Huls America, Inc. ( 1995) Submission of Product Chemistry Data in Support of the Registration of Nuosept BIT Technical. Transmittal of 2 Studies.

43803800 Huls America, Inc. ( 1995) Submission of Toxicology Data in Support of the Registration of NUOSEPT BIT Technical. Transmittal of 5 Studies.

43803900 Huls America Inc. ( 1995) Submission of product chemistry and toxicity data in support of registration for Nuosept 495 Preservative. Transmittal of 7 studies.

43873800 Zeneca, Inc. ( 1995) Submission of Product Chemistry Data in Support of the Registration of Proxel XL 2. Transmittal of 1 Study.

43975300 Zeneca Inc. ( 1996) Submission of Product Chemistry Data in Support of the Registration Amendment for PROXEL Press Paste. Transmittal of 2 Studies.

44051200 Zeneca Inc. ( 1996) Submission of Product Chemistry Data in Support of the Registration of Proxel XL 2. Transmittal of 1 Study.

44126300 Nipa Hardwicke, Inc. ( 1996) Submission of Product Chemistry Data in Support of the Application for Registration of Nipacide BIT 10. Transmittal of 1 Study.

44133000 Huls America Inc. ( 1996) Submission of Product Chemistry Data in Support of the Registration for Nuosept 495 Preservative. Transmittal of 1 Study.

44182100 PMC Specialties Group, Inc. ( 1996) Submission of Environmental Fate Data in Support of the Application for Registration of RJ Advantage, Inc.' s XBINX. Transmittal of 1 Study.

44211000 Zeneca, Inc. ( 1997) Submission of Product Chemistry Data in Support of the Amended Registration for Proxel Press Paste. Transmittal of 3 Studies.

44270700 Zeneca, Inc. ( 1997) Submission of Product Chemistry Data in Support of the Amended Registration for Proxel Press Paste. Transmittal of 2 Studies.

44290100 Calgon Corp. ( 1997) Submission of Product Chemistry and Toxicity Data in Support of the Product Specific RED for 1,2 Dibromo 2,4 dicyanobutane Containing Product Biochek 410. Transmittal of 5 Studies.

44398400 RJ Advantage Inc. ( 1997) Submission of Toxicity Data in Support of the Registration for XBINX. Transmittal of 3 Studies.

44450400 PMC Specialties Group, Inc. ( 1997) Submission of Product Chemistry Data in Support of the Registration of XBINX. Transmittal of 1 Study. 136 44482900 Cincinnati Specialties, Inc. ( 1998) Submission of Hazard to Wildlife Data in Support of the Registration of XBINX. Transmittal of 1 Study.

44514400 PMC Specialties Group, Inc. ( 1998) Submission of Product Chemistry Data in Support of the Application for Registration of XBINX 50W. Transmittal of 3 Studies.

44564000 PMC Specialties Group, Inc. ( 1998) Submission of Toxicity Data in Support of the Application for Registration of XBINX 50W. Transmittal of 2 Studies.

44671500 Cincinnati Specialties, Inc. ( 1998) Submission of Environmental Fate Data in Support of the Application for Registration of XBINX. Transmittal of 1 Study.

44726900 Zeneca, Inc. ( 1999) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Proxel TN. Transmittal of 10 Studies.

44746200 Zeneca Inc. ( 1998) Submission of Toxicity Data in Support of the Application for Registration of Proxtel TN. Transmittal of 1 Study.

44810500 Trutec Industries, Inc. ( 1999) Submission of Product Chemistry Data in Support of the Application for Registration of Palene 610 C. Transmittal of 1 Study.

44908200 PMC Specialties Group ( 1999) Submission of Product Chemistry Data in Support of the Registration of XBINX 88. Transmittal of 1 Study.

44959800 Avecia Biocides ( 1999) Submission of Toxicity Data in Support of the Registration of Proxel GXL. Transmittal of 2 Studies.

44966000 Avecia, Inc. ( 1999) Submission of Toxicity Data in Support of the Registration of Proxel GXL. Transmittal of 1 Study.

44981600 Thor Chemie GmbH ( 1999) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide BIT. Transmittal of 7 Studies.

44982500 Thor Chemie GmbH ( 1999) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide B20. Transmittal of 5 Studies.

45009700 Thor Chemie GmbH ( 1999) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide BIT. Transmittal of 1 Study.

45026000 Creanova, Inc. ( 2000) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Nuosept 485. Transmittal of 8 Studies.

45075600 Thor Chemie GmbH ( 2000) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide BW10. Transmittal of 5 Studies.

45076000 Thor Chemie GmbH ( 2000) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide BW20. Transmittal of 5 Studies.

45086900 NIPA Inc. ( 2000) Submission of Product Chemistry Data in Support of the 137 Application for Registration of Nipacide BFW. Transmittal of 5 Studies.

45100700 NIPA Inc. ( 2000) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Nipacide CBX. Transmittal of 9 Studies.

45116500 Thor Chemie GmbH ( 2000) Submission of Product Chemistry Data in Support of the Application for Registration of Acticide B10. Transmittal of 5 Studies.

45133800 Creanova Inc. ( 2000) Submission of Toxicity Data in Support of the Application for Registration of Nuosept 485 Preservative. Transmittal of 1 Study.

45175000 Cincinnati Specialties, Inc. ( 2000) Submission of Toxicity Data in Support of the Application for Registration of XBINX 17G. Transmittal of 1 Study.

45179800 Avecia Inc. ( 2000) Submission of Product Chemistry Data in Support of the Application for Registration of Proxel TN. Transmittal of 1 study.

45184600 MB Research Laboratories ( 2000) Submission of Toxicity Data in Support of the Registration of XBINX 88. Transmittal of 1 Study.

45216600 Nalco Chemical Company ( 2000) Submission of Toxicity Data in Support of the Reregistration of the 1,2 dibromo 2, 4 dicyanobutane and 1,2 benzisothiazolin 3 one Containing Product Biochek 410. Transmittal of 1 Study.

45219100 Avecia ( 2000) Submission of Product Chemistry Data in Support of the Registration of Proxel GXL. Transmittal of 1 Study.

45236800 Troy Corp. ( 2000) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Mergal K10N. Transmittal of 7 Studies.

45240300 PMC Specialties Group, Inc. ( 2000) Submission of Toxicity Data in Support of the Application for Registration of XBINX 17G. Transmittal of 2 Studies.

45308900 PMC Specialties Group, Inc. ( 2001) Submission of Toxicity Data in Support of the Application for the Registration of XBINX 19G. Transmittal of 1 Study.

45312600 Avecia, Inc. ( 2001) Submission of Toxicity Data in Support of the Application for the Registration of Proxel TN. Transmittal of 1 Study.

45358300 Avecia, Inc. ( 2001) Submission of Product Chemistry Data in Support of the Application for the Registration of PROXEL Ultra Technical. Transmittal of 2 Studies.

45389700 Avecia, Inc. ( 2001) Submission of Product Chemistry Data in Support of the Application for the Registration of Proxel Ultra Technical. Transmittal of 2 Studies.

45410400 Troy Chemical Corporation ( 2001) Submission of Product Chemistry and Toxicity Data in Support of the Application for the Registration of Polyphase 663. Transmittal of 9 Studies. 138 45431300 Creanova Inc. ( 2001) Submission of Product Chemistry Data in Support of the Registration of Nuosept Bit Technical. Transmittal of 2 Studies.

45431301 Comb, A. ( 2000) 1,2 Benzisothiazol 3( 2H) One Five Batch Analysis: Lab Project Number: DNN/ 131: DNN131/ 004725. Unpublished study prepared by Huntingdon Life Sciences Ltd. 34 p. { OPPTS 830.1700}

45437100 Rohm and Haas ( 2001) Submission of Toxicity Data in Support of the Application for Registration of Rocima 607 Industrial Microbicide. Transmittal of 6 Studies.

45444700 Acti Chem Specialties, Inc. ( 2001) Submission of Toxicity and Product Chemistry Data in Support of the Application for Registration of Acticide MBS. Transmittal of 10 Studies.

45489400 Thor GmbH ( 2001) Submission of Toxicity Data in Support of the Application for Registration of Acticide MBS. Transmittal of 2 Studies.

45489401 Coscia, A. ( 2001) Summary of the Acute Toxicity Characteristics of Acticide MBS: Lab Project Number: NO. 01 TOX SUMMARY/ MBS. Unpublished study prepared by Acti Chem Specialties, Inc. 5 p. { OPPTS 870.1100, 870.1200, 870.1300, 870.2400, 870.2500, 870.2600}

45496300 Rohm and Haas Co ( 2001) Submission of Product Chemistry Data in Support of the Application of Registration of Rocima 607 Industrial Microbicide. Transmittal of 1 Study.

45498300 Avecia Inc. ( 2001) Submission of Product Chemistry Data in Support of the Registration of Proxel Ultra Technical. Transmittal of 1 Study.

45515800 Prom Chem Ltd ( 2001) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Promex BIT. Transmittal of 4 Studies.

45534600 Prom Chem Ltd. ( 2001) Submission of Toxicity Data in Support of the Application of Registration of Promex BIT. Transmittal of 3 Studies.

45553400 Lonza, Inc. ( 2001) Submission of Product Chemistry and Toxicity Data in Support of the Applications for Registration of Dantoserve SG and Dantoserve MS. Transmittal of 7 Studies.

45553800 Prom Chem Ltd. ( 2001) Submission of Product Chemistry Data in Support of the Application for Registration of Promex BIT. Transmittal of 1 Study.

45633900 Rohm and Haas Company ( 2002) Submission of Toxicity Data in Support of the Application for Registration of Rocima 607. Transmittal of 1 Study.

45643500 THOR GmbH ( 2002) Submission of Product Chemistry Data in Support of the Registration of Acticide Bit. Transmittal of 2 Studies.

45686200 Trutec Industries, Inc. ( 2002) Submission of Product Chemistry Data in Support 139 of the Application for Registration of Palene 710 C. Transmittal of 1 Study.

45746200 Trutec Industries, Inc. ( 2002) Submission of Product Chemistry Data in Support of the Application for Registration of Palene 710 C. Transmittal of 1 Study.

45770300 Avecia Inc. ( 2002) Submission of Toxicity Data in Support of the Registration of Proxel Press Paste. Transmittal of 1 Study.

45793600 Troy Corporation ( 2002) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Troysan 680. Transmittal of 6 Studies.

45799800 Troy Corporation ( 2002) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Troysan 680. Transmittal of 2 Studies.

45929800 Prom Chem Ltd. ( 2003) Submission of Environmental Fate Data in Support of the Amended Registration of Promex BIT. Transmittal of 2 Studies.

46009000 Prom Chem Ltd ( 2003) Submission of Toxicity Study in Support of the Amended Registration of Promex BIT. Transmittal of 3 Studies.

46043900 Avecia Inc. ( 2003) Submission of Product Chemistry Data in Support of the Registration of Proxel DL. Transmittal of 1 Study.

46063600 Avecia Inc ( 2003) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Proxel AQ Preservative. Transmittal of 7 Studies.

46097100 Avecia Biocides ( 2003) Submission of Toxicity Data in Support of the Reregistration of Proxel Containing Product Proxel Press Paste ( BIT). Transmittal of 1 Study.

46113100 PromChemie Ag ( 2003) Submission of Product Chemistry Data in Support of the Application for Registration of Promex 20S. Transmittal of 1 Study.

46113200 PromChemie Ag ( 2003) Submission of Product Chemistry Data in Support of the Application for Registration of Promex 10S. Transmittal of 1 Study.

46113300 PromChemie Ag ( 2003) Submission of Product Chemistry Data in Support of the Application for Registration of Promex 20D. Transmittal of 1 Study.

46179900 Clariant Corporation ( 2003) Submission of Toxicity Data in Support of the Application for Registration of Nipacide TBX. Transmittal of 3 Studies.

46184900 PromChemie AG ( 2004) Submission of Product Chemistry Data in Support of the Application for Registration of Promex 20D. Transmittal of 1 Study.

46185100 PromChemie AG ( 2004) Submission of Product Chemistry Data in Support of the Application for Registration of Promex 10S. Transmittal of 1 Study.

46185300 PromChemie AG ( 2004) Submission of Product Chemistry Data in Support of 140 the Application for Registration of Promex 20S and Promex 10S. Transmittal of 1 Study 46187400 PromChemie AG ( 2004) Submission of Product Chemistry Data in Support of Application for Registration of Promex 20D. Transmittal of 1 Study.

46239600 Avecia, Inc. ( 2004) Submission of Product Chemistry Data in Support of the Reregistration of Proxel Press Paste. Transmittal of 1 Study.

46246900 Prom Chem Limited ( 2004) Submission of Product Chemistry Data in Support of the Registration of Promex BIT. Transmittal of 1 Study.

46287400 Thor GmbH ( 2004) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Acticide MBL 5515. Transmittal of 9 Studies.

46327900 Clariant Corporation ( 2004) Submission of Toxicity Data in Support of the Reregistration of 1,2 Benzisothiazolin 3 one. Transmittal of 1 Study.

46346200 Prom Chem Ltd ( 2004) Submission of Toxicity Data in Support of FIFRA 6( a)( 2) Data Requirements for Promex BIT. Transmittal of 1 Study.

46357400 Acti Chem Specialties Inc. ( 2004) Submission of Product Chemistry Data in Support of the Amended Registration of Acticide BW20. Transmittal of 1 Study.

46382700 THOR GMBH ( 2004) Submission of Product Chemistry Data in Support of the Amended Registration of Acticide B20. Transmittal of 1 Study.

46448000 Thor Gmbh ( 2005) Submission of Toxicity Data in Support of the Application for Registration of Acticide MBL 5515. Transmittal of 1 Study.

46455000 Sanitized, Inc. ( 2004) Submission of Efficacy Data in Support of the Application for Registration of Sanitized Brand TB 83 35 MUP DM. Transmittal of 1 Study.

46455001 Klein, S. ( 2004) Laboratory Assessment of the Efficacy of a Fabric Treatment to Control House Dust Mites. Project Number: 972/ 0904R. Unpublished study prepared by Laboratoire T. E. C/ Techniques Environnement Consultants. 18 p.

46460300 Sanitized, Inc. ( 2005) Submission of Product Chemistry and Efficacy Data in Support of the Application for Registration of Sanitized Brand TB 83 35 DM. Transmittal of 3 Studies.

46460301 Klein, S. ( 2004) Laboratory Assessment of the Efficacy of a Fabric Treatment to Control House Dust Mites. Project Number: 972/ 0904R, NF/ G/ 39/ 011. Unpublished study prepared by Laboratoire T. E. C/ Techniques Environnement Consultants. 18 p.

46467900 Arch Chemicals, Inc. ( 2005) Submission of Product Chemistry Data in Support of the Application for Registration of Proxel UL 7 Preservative. Transmittal of 4 Studies. 141 46490200 Arch Chemicals, Inc. ( 2005) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Proxel BN Preservative. Transmittal of 10 Studies.

46496800 Sanitized, Inc. ( 2005) Submission of Exposure and Risk Data in Support of the Application for Registration of Sanitized Brand TB 83 35 MUP DM. Transmittal of 1 Study.

46496801 Marconi, C. ( 2004) Risk Assessment of Sanitized TB 83 85. Project Number: 502/ 003. Unpublished study prepared by Sanitized AG. 118 p.

46504600 Clariant Corporation ( 2003) Submission of Product Chemistry Data in Support of the Application of Registration of Nipacide TBX. Transmittal of 7 Studies.

46504605 Whatmough, M. ( 2002) Determination of Viscosity for Nipacide TBX. Project Number: MOA019D, CAL011. Unpublished study prepared by Clariant UK Ltd. and Nipa Laboratories, Ltd. 6 p.

46509300 Arch Chemicals, Inc. ( 2005) Submission of Product Chemistry Data in Support of the Application for Registration of Proxel BN Preservative. Transmittal of 2 Studies.

46527400 Troy Chemical Corp. ( 2005) Submission of Product Chemistry Data in Support of the Application for Registration of Mergal BIT Paste. Transmittal of 2 Studies.

46527700 Arch Chemicals, Inc. ( 2005) Submission of Product Chemistry Data in Support of the Application for Registration of Proxel BN Preservative. Transmittal of 1 Study.

46528000 Troy Chemical Corp. ( 2005) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Mergal BIT 20. Transmittal of 8 Studies.

46542200 ProChemie AG ( 2005) Submission of Product Chemistry Data in Support of the Amended Registration of Promex 20D. Transmittal of 1 Study.

46565900 Troy Chemical Corp. ( 2005) Submission of Product Chemistry Data in Support of the Application for the Registration of Troy 2063. Transmittal of 2 Studies.

46603400 Thor GmbH ( 2005) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Acticide MBL. Transmittal of 8 Studies.

93053000 Ici Americas Inc. ( 1990) Reregistration Phase 3 Response: Benzisothiazolin 3 one.

93053999 Ici Americas Inc. ( 1990) Reregistration Phase 3 Response: Benzisothiazolin 3 one. Correspondence and Supporting Material.

93287000 Nipa Laboratories Inc. ( 1993) Reregistration Phase 3 Response: 142 Benzisothiazolin 3 one.

93287999 Nipa Laboratories Inc. ( 1993) Reregistration Phase 3 Response: Benzisothiazolin 3 one. Correspondence and Supporting Material. 143 Appendix E. Generic Data Call In The Agency intends to issue a Generic Data Call In at a later date. 144 Appendix F. Product Specific Data Call In The Agency intends to issue a Product Specific Data Call In at a later date. 145 Appendix G. ANTIMICROBIAL DIVISION'S BATCHING OF PRODUCTS CONTAINING BENZISOTHIAZOLIN 3 ONE AS THE ACTIVE INGREDIENT FOR MEETING ACUTE TOXICITY DATA REQUIREMENTS FOR REREGISTRATION In an effort to reduce the time, resources and number of animals needed to fulfill the acute toxicity data requirements for reregistration of products containing Benzisothiazolin 3 one as an active ingredient, the Agency has batched products which can be considered similar for purposes of acute toxicity. Factors considered in the sorting process include each product's active and inert ingredients ( identity, percent composition and biological activity), type of formulation ( e. g., emulsifiable concentrate, aerosol, wettable powder, granular), and labeling ( e. g., signal word, use classification, precautionary labeling). Note that the Agency is not describing batched products as " substantially similar," since they may not have similar use patterns.

Using available information, batching has been accomplished by the process described in the preceding paragraph. Notwithstanding the batching process, the Agency reserves the right to require, at any time, acute toxicity data for an individual product should the need arise.

Registrants of products within a batch may choose to cooperatively generate, submit or cite a single battery of six acute toxicological studies to represent all the products within that batch. It is the registrants' option to participate in the process with all other registrants, only some of the other registrants, or only their own products within a batch, or to generate all the required acute toxicological studies for each of their own products. If a registrant chooses to generate the data for a batch, he/ she must use one of the products within the batch as the test material. If a registrant chooses to rely upon previously submitted acute toxicity data, he/ she may do so provided that the data base is complete and valid by today's standards ( see partial list of acceptance criteria attached), the formulation tested is considered by EPA to be similar for acute toxicity, and the formulation has not been significantly altered since submission and acceptance of the acute toxicity data. The Agency must approve any new or canceled formulations ( that were presented to the Agency after the completion of the RED) before data derived from them can be used to cover other products in a batch. Regardless of whether new data is generated or existing data is referenced, registrants must clearly identify the test material by EPA Registration Number. If more than one confidential statement of formula ( CSF) exists for a product, the registrant must indicate the formulation actually tested by identifying the corresponding CSF.

In deciding how to meet the product specific data requirements, registrants must follow the directions given in the Data Call In Notice and its attachments appended to the RED. The DCI Notice contains two response forms which are to be completed and submitted to the Agency within 90 days of receipt. The first form, " Data Call In Response," asks whether the registrant will meet the data requirements for each product. The second form, " Requirements Status and Registrant's Response," lists the product specific data required for each product, including the standard six acute toxicity tests. A registrant who wishes to participate in a batch must decide whether he/ she will provide the data or depend on someone else to do so. If a registrant supplies the data to support a batch of products, he/ she must select one of the following options: 146 Developing Data ( Option 1), Submitting an Existing Study ( Option 4), Upgrading an Existing Study ( Option 5) or Citing an Existing Study ( Option 6). If a registrant depends on another's data, he/ she must choose among: Cost Sharing ( Option 2), Offers to Cost Share ( Option 3) or Citing an Existing Study ( Option 6). If a registrant does not want to participate in a batch, the choices are Options 1, 4, 5 or 6. However, a registrant should know that choosing not to participate in a batch does not preclude other registrants in the batch from citing his/ her studies and offering to cost share ( Option 3) those studies.

If a registrant would like to have the batching status of a product reconsidered, he/ she needs to submit detailed information on the product, including a detailed rationale for the inclusion of the product into a batch. An MSDS for each " inert" ingredient should be included where possible. However, registrants and manufacturers should realize that the more unusual their formulation is, the less likely it is to be able to batch that product.

Table 1 displays the batches for products containing the active ingredient Benzisothiazolin 3 one. Table 1 Batch Registration Number Percent Active Ingredient 1 365 82 Benzisothiazolin 3 one ... 87.6%

1258 1261 Benzisothiazolin 3 one ... 80.0%

1258 1268 Benzisothiazolin 3 one ... 84.0%

1529 36 Benzisothiazolin 3 one ... 82.0%

73930 1 Benzisothiazolin 3 one ... 83.8%

1A* 1258 1254 Benzisothiazolin 3 one ... 72.0%

49403 20 Benzisothiazolin 3 one ... 63.0%

67071 21 Benzisothiazolin 3 one ... 72.0%

2 1258 1255 Benzisothiazolin 3 one ... 19.3%

1258 1260 Benzisothiazolin 3 one ... 19.3%

1529 34 Benzisothiazolin 3 one ... 19.0%

49403 14 Benzisothiazolin 3 one ... 18.0%

67071 22 Benzisothiazolin 3 one ... 20.0%

67071 23 Benzisothiazolin 3 one ... 20.0% 147 70465 3 Benzisothiazolin 3 one ... 19.8%

80285 2 Benzisothiazolin 3 one ... 19.0%

80285 3 Benzisothiazolin 3 one ... 19.0%

3 1258 1256 Benzisothiazolin 3 one ... 9.0%

1258 1262 Benzisothiazolin 3 one ... 9.0%

1258 1284 Benzisothiazolin 3 one ... 9.25%

1529 39 Benzisothiazolin 3 one ... 8.5%

5383 107 Benzisothiazolin 3 one ... 9.5%

49403 26 Benzisothiazolin 3 one ... 8.5%

67071 24 Benzisothiazolin 3 one ... 10.0%

67071 25 Benzisothiazolin 3 one ... 10.0%

80285 1 Benzisothiazolin 3 one ... 9.0%

4* 1258 1289 Benzisothiazolin 3 one ... 7.0%

49403 27 Benzisothiazolin 3 one ... 7.0%

* Batch 1A: The three products placed in Batch 1A may cite data from any of the products in Batch # 1. Otherwise, the products may be considered to be in the " No Batch" Group.

* Batch 4: The two products placed in Batch 4 may cite each other's eye irritation data only if the data indicate corrosiveness. 148 Table 2 lists the products that fall into the " No Batch" group. These products can not be batched because they were not considered to be similar to the other products in terms of acute toxicity or because there was insufficient information available to assist in making the decision. Registrants of these products may only cite data obtained from the specific product itself to support the acute toxicity data requirements for that product. No other product data will suffice.

Table 2. No Batch Group Registration Number Percent Active Ingredient( s)

707 295 Benzisothiazolin 3 one ... 12.0% Bronopol ... 10.0%

1258 1248 Benzisothiazolin 3 one ... 4.5% Hexahydro 1,3,5 tris( 2 hydroxythyl) Striazine ... 50.5%

1258 1257 Benzisothiazolin 3 one ... 12.0% Zinc 2 Pyridinethiol 1 oxide ... 8.0%

1258 1290 Benzisothiazolin 3 one ... 13.5% Bronopol ... 6.5%

3090 217 Benzisothiazolin 3 one ... 0.9% Octhilinone ... 2.25%

5383 111 Benzisothiazolin 3 one ... 10.9% 1,3, Bis( hydroxymethyl) 5,5 dimethylhydantoin ... 12.5% Hydroxymethyl 5,5 dimethylhydantoin ... 2.9%

6836 306 Benzisothiazolin 3 one ... 1.1% 1,3, Bis( hydroxymethyl) 5,5 dimethylhydantoin ... 29.4% Hydroxymethyl 5,5 dimethylhydantoin ... 27.9%

6836 307 Benzisothiazolin 3 one ... 1.1% 1,3, Bis( hydroxymethyl) 5,5 dimethylhydantoin ... 29.4% Hydroxymethyl 5,5 dimethylhydantoin ... 27.9%

39967 39 Benzisothiazolin 3 one ... 6.0% 1,2 dibromo 2,4 dicyanobutane ... 19.0% 149 49403 28 Benzisothiazolin 3 one ... 5.0% 5 Chloro 2 Methyl 4 isothiazolin 3 one ... 0.74% 2 Methyl 4 isothiazolin 3 one ... 0.26%

67071 29 Benzisothiazolin 3 one ... 2.5% 2 Methyl 4 isothiazolin 3 one ... 2.5%

67071 45 Benzisothiazolin 3 one ... 5.0% 2 Methyl 4 isothiazolin 3 one ... 5.0% Bronopol ... 15.0%

68575 2 Benzisothiazolin 3 one ... 4.5% 150 Appendix H. List of All Registrants Sent the Data Call In A list of registrants sent the Data Call In will be posted at a later date. 151 Appendix I. List of Available Related Documents and Electronically Available Forms Pesticide Registration Forms are available at the following EPA internet site: http:// www. epa. gov/ opprd001/ forms/ .

Pesticide Registration Forms ( These forms are in PDF format and require the Acrobat reader)

Instructions 1. Print out and complete the forms. ( Note: Form numbers that are bolded can be filled out on your computer then printed.)

2. The completed form( s) should be submitted in hardcopy in accord with the existing policy.

3. Mail the forms, along with any additional documents necessary to comply with EPA regulations covering your request, to the address below for the Document Processing Desk.

DO NOT fax or e mail any form containing ` Confidential Business Information' or ` Sensitive Information.'

If you have any problems accessing these forms, please contact Nicole Williams at ( 703) 308 5551 or by e mail at williams. nicole@ epamail. epa. gov.

The following Agency Pesticide Registration Forms are currently available via the internet at the following locations: 8570 1 Application for Pesticide Registration/ Amendment http:// www. epa. gov/ opprd001/ forms/ 8570 1. pdf 8570 4 Confidential Statement of Formula http:// www. epa. gov/ opprd001/ forms/ 8570 4. pdf 8570 5 Notice of Supplemental Registration of Distribution of a Registered Pesticide Product http:// www. epa. gov/ opprd001/ forms/ 8570 5. pdf 8570 17 Application for an Experimental Use Permit http:// www. epa. gov/ opprd001/ forms/ 8570 17. pdf 8570 25 Application for/ Notification of State Registration of a Pesticide To Meet a Special Local Need http:// www. epa. gov/ opprd001/ forms/ 8570 25. pdf 8570 27 Formulator's Exemption Statement http:// www. epa. gov/ opprd001/ forms/ 8570 27. pdf 8570 28 Certification of Compliance with Data Gap Procedures http:// www. epa. gov/ opprd001/ forms/ 8570 28. pdf 8570 30 Pesticide Registration Maintenance Fee Filing http:// www. epa. gov/ opprd001/ forms/ 8570 30. pdf 8570 32 Certification of Attempt to Enter into an Agreement with other Registrants for Development of Data http:// www. epa. gov/ opprd001/ forms/ 8570 32. pdf 8570 34 Certification with Respect to Citations of Data ( in PR Notice 98 5) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr98 5. pdf 8570 35 Data Matrix ( in PR Notice 98 5) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr98 5. pdf 8570 36 Summary of the Physical/ Chemical Properties ( in PR Notice 98 1) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr98 1. pdf 152 8570 37 Self Certification Statement for the Physical/ Chemical Properties ( in PR Notice 98 1) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr98 1. pdf Pesticide Registration Kit www. epa. gov/ pesticides/ registrationkit/.

Dear Registrant:

For your convenience, we have assembled an online registration kit that contains the following pertinent forms and information needed to register a pesticide product with the U. S. Environmental Protection Agency's Office of Pesticide Programs ( OPP):

1. The Federal Insecticide, Fungicide, and Rodenticide Act ( FIFRA) and the Federal Food, Drug and Cosmetic Act ( FFDCA) as Amended by the Food Quality Protection Act ( FQPA) of 1996.

2. Pesticide Registration ( PR) Notices a. 83 3 Label Improvement Program  Storage and Disposal Statements b. 84 1 Clarification of Label Improvement Program c. 86 5 Standard Format for Data Submitted under FIFRA d. 87 1 Label Improvement Program for Pesticides Applied through Irrigation Systems ( Chemigation)

e. 87 6 Inert Ingredients in Pesticide Products Policy Statement f. 90 1 Inert Ingredients in Pesticide Products; Revised Policy Statement g. 95 2 Notifications, Non notifications, and Minor Formulation Amendments h. 98 1 Self Certification of Product Chemistry Data with Attachments ( This document is in PDF format and requires the Acrobat reader.)

Other PR Notices can be found at http:// www. epa. gov/ opppmsd1/ PR_ Notices.

3. Pesticide Product Registration Application Forms ( These forms are in PDF format and will require the Acrobat reader.)

a. EPA Form No. 8570 1, Application for Pesticide Registration/ Amendment b. EPA Form No. 8570 4, Confidential Statement of Formula c. EPA Form No. 8570 27, Formulator's Exemption Statement d. EPA Form No. 8570 34, Certification with Respect to Citations of Data 153 e. EPA Form No. 8570 35, Data Matrix 4. General Pesticide Information ( Some of these forms are in PDF format and will require the Acrobat reader.)

a. Registration Division Personnel Contact List b. Biopesticides and Pollution Prevention Division ( BPPD) Contacts c. Antimicrobials Division Organizational Structure/ Contact List d. 53 F. R. 15952, Pesticide Registration Procedures; Pesticide Data Requirements ( PDF format)

e. 40 CFR Part 156, Labeling Requirements for Pesticides and Devices ( PDF format)

f. 40 CFR Part 158, Data Requirements for Registration ( PDF format)

g. 50 F. R. 48833, Disclosure of Reviews of Pesticide Data ( November 27, 1985)

Before submitting your application for registration, you may wish to consult some additional sources of information. These include:

1. The Office of Pesticide Programs' Web Site 2. The booklet " General Information on Applying for Registration of Pesticides in the United States", PB92 221811, available through the National Technical Information Service ( NTIS) at the following address:

National Technical Information Service ( NTIS) 5285 Port Royal Road Springfield, VA 22161 The telephone number for NTIS is ( 703) 605 6000. Please note that EPA is currently in the process of updating this booklet to reflect the changes in the registration program resulting from the passage of the FQPA and the reorganization of the Office of Pesticide Programs. We anticipate that this publication will become available during the Fall of 1998.

3. The National Pesticide Information Retrieval System ( NPIRS) of Purdue University's Center for Environmental and Regulatory Information Systems. This service does charge a fee for subscriptions and custom searches. You can contact NPIRS by telephone at ( 765) 494 6614 or through their Web site.

4. The National Pesticide Telecommunications Network ( NPTN) can provide information on active ingredients, uses, toxicology, and chemistry of pesticides. You can contact NPTN by telephone at ( 800) 858 7378 or through their Web site: ace. orst. edu/ info/ nptn. 154 The Agency will return a notice of receipt of an application for registration or amended registration, experimental use permit, or amendment to a petition if the applicant or petitioner encloses with his submission a stamped, self addressed postcard. The postcard must contain the following entries to be completed by OPP:

Date of receipt EPA identifying number Product Manager assignment Other identifying information may be included by the applicant to link the acknowledgment of receipt to the specific application submitted. EPA will stamp the date of receipt and provide the EPA identifying File Symbol or petition number for the new submission. The identifying number should be used whenever you contact the Agency concerning an application for registration, experimental use permit, or tolerance petition. To assist us in ensuring that all data you have submitted for the chemical are properly coded and assigned to your company, please include a list of all synonyms, common and trade names, company experimental codes, and other names which identify the chemical ( including " blind" codes used when a sample was submitted for testing by commercial or academic facilities). Please provide a CAS number if one has been assigned. 155


[Federal Register Volume 81, Number 205 (Monday, October 24, 2016)]
[Notices]
[Pages 73122-73123]
[FR Doc No: 2016-25564]

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DEPARTMENT OF HOMELAND SECURITY

Federal Emergency Management Agency

[Internal Agency Docket No. FEMA-3380-EM; Docket ID FEMA-2016-0001]

North Carolina; Emergency and Related Determinations

AGENCY: Federal Emergency Management Agency, DHS.

ACTION: Notice.

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SUMMARY: This is a notice of the Presidential declaration of an
emergency for the State of North Carolina (FEMA-3380-EM), dated October
7, 2016, and related determinations.

DATES: Effective October 7, 2016.

FOR FURTHER INFORMATION CONTACT: Dean Webster, Office of Response and
Recovery, Federal Emergency Management Agency, 500 C Street SW.,
Washington, DC 20472,<PHONE_NUMBER>.

SUPPLEMENTARY INFORMATION: Notice is hereby given that, in a letter
dated October 7, 2016, the President issued an emergency declaration
under the authority of the Robert T. Stafford Disaster Relief and
Emergency Assistance Act, 42 U.S.C. 5121-5207 (the Stafford Act), as
follows:

    I have determined that the emergency conditions in the State of
North Carolina resulting from Hurricane Matthew beginning on October
4, 2016, and continuing, are of sufficient severity and magnitude to
warrant an emergency declaration under the Robert T. Stafford
Disaster Relief and Emergency Assistance Act, 42 U.S.C. 5121 et seq.
(``the Stafford Act''). Therefore, I declare that such an emergency
exists in the State of North Carolina.
    You are authorized to provide appropriate assistance for
required emergency measures, authorized under Title V of the
Stafford Act, to save lives and to protect property and public
health and safety, and to lessen or avert the threat of a
catastrophe in the designated areas. Specifically, you are
authorized to provide assistance for emergency protective measures
(Category B), limited to direct Federal assistance, under the Public
Assistance program.
    Consistent with the requirement that Federal assistance is
supplemental, any Federal funds provided under the Stafford Act for
Public Assistance will be limited to 75 percent of the total
eligible costs. In order to provide Federal assistance, you are
hereby authorized to allocate from funds available for these
purposes such amounts as you find necessary for Federal emergency
assistance and administrative expenses.
    Further, you are authorized to make changes to this declaration
for the approved assistance to the extent allowable under the
Stafford Act.

    The Federal Emergency Management Agency (FEMA) hereby gives notice
that pursuant to the authority vested in the Administrator, Department
of Homeland Security, under Executive Order 12148, as amended,
Elizabeth Turner, of FEMA is appointed to act as the Federal
Coordinating Officer for this declared emergency.
    The following areas of the State of North Carolina have been
designated as adversely affected by this declared emergency:

    Alamance, Anson, Beaufort, Bertie, Bladen, Brunswick, Camden,
Carteret, Caswell, Chatham, Chowan, Columbus, Craven, Cumberland,
Currituck, Dare, Davidson, Davie, Duplin, Durham, Edgecombe,
Forsyth, Franklin, Gates, Granville, Greene, Guilford, Halifax,
Harnett, Hertford, Hoke, Hyde, Johnston, Jones, Lee, Lenoir, Martin,
Montgomery, Moore, Nash, New Hanover, Northampton, Onslow, Orange,
Pamlico, Pasquotank, Pender, Perquimans, Person, Pitt, Randolph,
Richmond, Robeson, Rockingham, Sampson, Scotland, Stokes, Surry,
Tyrrell, Vance, Wake, Warren, Washington, Wayne, Wilson, and Yadkin
Counties for emergency protective measures (Category B), limited to
direct federal assistance, under the Public Assistance program.

The following Catalog of Federal Domestic Assistance Numbers (CFDA)
are to be used for reporting and drawing funds: 97.030, Community
Disaster Loans; 97.031, Cora Brown Fund; 97.032, Crisis Counseling;
97.033, Disaster Legal Services; 97.034, Disaster Unemployment
Assistance (DUA); 97.046, Fire Management Assistance Grant; 97.048,
Disaster Housing Assistance to Individuals and Households In
Presidentially Declared Disaster Areas; 97.049, Presidentially
Declared Disaster Assistance--Disaster Housing Operations for
Individuals and Households; 97.050, Presidentially Declared Disaster
Assistance to Individuals and Households--Other Needs; 97.036,
Disaster Grants--Public Assistance

(Presidentially Declared Disasters); 97.039, Hazard Mitigation
Grant.

W. Craig Fugate,
Administrator, Federal Emergency Management Agency.
[FR Doc. 2016-25564 Filed 10-21-16; 8:45 am]
 BILLING CODE 9111-23-P


[Federal Register Volume 84, Number 239 (Thursday, December 12, 2019)]
[Notices]
[Page 68007]
[FR Doc No: 2019-26805]

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DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

[Summary Notice No. 2019-67]

Petition for Exemption; Summary of Petition Received; Daniel
Orcutt

AGENCY: Federal Aviation Administration (FAA), Department of
Transportation (DOT).

ACTION: Notice.

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SUMMARY: This notice contains a summary of a petition seeking relief
from specified requirements of Federal Aviation Regulations. The
purpose of this notice is to improve the public's awareness of, and
participation in, the FAA's exemption process. Neither publication of
this notice nor the inclusion or omission of information in the summary
is intended to affect the legal status of the petition or its final
disposition.

DATES: Comments on this petition must identify the petition docket
number and must be received on or before January 2, 2020.

ADDRESSES: Send comments identified by docket number FAA-2019-0733
using any of the following methods:
     Federal eRulemaking Portal: Go to http://www.regulations.gov and follow the online instructions for sending your
comments electronically.
     Mail: Send comments to Docket Operations, M-30; U.S.
Department of Transportation, 1200 New Jersey Avenue SE, Room W12-140,
West Building Ground Floor, Washington, DC 20590-0001.
     Hand Delivery or Courier: Take comments to Docket
Operations in Room W12-140 of the West Building Ground Floor at 1200
New Jersey Avenue SE, Washington, DC 20590-0001, between 9 a.m. and 5
p.m., Monday through Friday, except Federal holidays.
     Fax: Fax comments to Docket Operations at<PHONE_NUMBER>.
    Privacy: In accordance with 5 U.S.C. 553(c), DOT solicits comments
from the public to better inform its rulemaking process. DOT posts
these comments, without edit, including any personal information the
commenter provides, to http://www.regulations.gov, as described in the
system of records notice (DOT/ALL-14 FDMS), which can be reviewed at
http://www.dot.gov/privacy.
    Docket: Background documents or comments received may be read at
http://www.regulations.gov at any time. Follow the online instructions
for accessing the docket or go to the Docket Operations in Room W12-140
of the West Building Ground Floor at 1200 New Jersey Avenue SE,
Washington, DC 20590-0001, between 9 a.m. and 5 p.m., Monday through
Friday, except Federal holidays.

FOR FURTHER INFORMATION CONTACT: Brittany Newton<PHONE_NUMBER>, Office
of Rulemaking, Federal Aviation Administration, 800 Independence Avenue
SW, Washington, DC 20591.
    This notice is published pursuant to 14 CFR 11.85.

    Issued in Washington, DC, on November 29, 2019.
Brandon Roberts,
Acting Executive Director, Office of Rulemaking.

Petition for Exemption

    Docket No.: FAA-2019-0733.
    Petitioner: Daniel Orcutt.
    Section(s) of 14 CFR Affected: Sec.  121.436(a)(3).
    Description of Relief Sought: Section 121.436(a)(3) requires that
prior to serving as Pilot-in-Command (PIC) in part 121 operations, a
pilot must have 1,000 hours while operating under one of the following
conditions: Second-in Command (SIC) under part 121 operations, PIC
under Sec.  91.1053(a)(2)(i) operations, PIC under Sec.  135.243(a)(1)
operations, or any combination thereof. Section 121.436(c) allows for
500 hours of military flight time to be credited toward the 1,000
flight hour requirement of Sec.  121.436(a)(3), provided the flight
time was obtained as PIC of a multiengine turbine-powered, fixed-wing
airplane in an operation requiring more than one pilot. Mr. Daniel J.
Orcutt seeks an exemption from Sec.  121.436(a)(3) and (c) to allow use
of his military PIC experience to fulfill the 1,000 hours as SIC under
part 121 operations requirement.

[FR Doc. 2019-26805 Filed 12-11-19; 8:45 am]
 BILLING CODE 4910-13-P