Kathy Kaufman/RTP/USEPA/US

05/05/2008 11:45 AM

To

Zachary Pekar/RTP/USEPA/US@EPA

cc

Ron Evans/RTP/USEPA/US@EPA, Tricia Crabtree/RTP/USEPA/US@EPA, Karen Martin/RTP/USEPA/US@EPA

Subject

Fw: Updated lead benefits chapter

fyi.

Kathy Kaufman

EPA/OAQPS Mail Code C539-03

Research Triangle Park, NC 27711

Phone<PHONE_NUMBER>

Fax<PHONE_NUMBER>

----- Forwarded by Kathy Kaufman/RTP/USEPA/US on 05/05/2008 11:43 AM -----

"King, Heidi R."<EMAIL_ADDRESS> 05/05/2008 11:35 AM

To

Neal Fann/RTP/USEPA/US@EPA

cc

Lydia Wegman/RTP/USEPA/US@EPA, Ron Evans/RTP/USEPA/US@EPA, Kathy Kaufman/RTP/USEPA/US@EPA, Onyemaechi Nweke/DC/USEPA/US@EPA

Subject

RE: Updated lead benefits chapter

Hi Neal and Ron,

-  I marked up just the first page of Chap 5 to give a sense of the caveats commenters sought on this initial RIA, as well as the direction for the final.  Don’t hesitate to call if you want to talk through the comments.

-  Also, one commenter asked for deletion of Neonatal Mortality.  I believe this might be both uncertain and also at much higher lead levels than are typically seen under current conditions.  Let me know if we should discuss.

-  Lastly, Hilts estimates a 1:6 ratio.  The 1:7 was, I believe, calculated by EPA using a pre- point that was a spike in the time-series decline.  If the RIA includes the 1:7, should we reference that this is an EPA calculation, and not from Hilts?  There are several places in the chapter where the 1:7 is attributed to Hilts.

With new reading glasses on,

heidi

From<EMAIL_ADDRESS><EMAIL_ADDRESS> Sent: Thursday, May 01, 2008 7:25 PM

To: King, Heidi R.

Cc<EMAIL_ADDRESS><EMAIL_ADDRESS><EMAIL_ADDRESS><EMAIL_ADDRESS> Subject: Updated lead benefits chapter

Heidi,

I'm passing back a new version of the lead benefits chapter. Ron indicated that I should send this along to you directly as a means of expediting the review process.

Compared to the last version we sent you, the three primary changes are:

--conforming edits to the RIA to reflect discussion of both air:blood uncertainty and the summary table of IQ functions found in the NPRM.

--in response to a request from OPEI, additional elaboration evaluating the adult endpoint literature. Specifically, I added language from the criteria document summarizing the limitations of the more recently published lead-cardiovascular mortality studies.

--added discussion of the effect of reductions in background blood-lead levels on our estimates of total benefits. Added footnotes to relevant results tables.

I apologize in advance if I've overlooked any of your comments. I'm hopeful that with these changes we can soon finalize this chapter.

Thanks,

Neal

_________________________________

Neal Fann

USEPA

Office of Air Quality Planning & Standards

Air Benefit and Cost Group

C439-02

RTP, NC 27711

voice:<PHONE_NUMBER>