    SEQ CHAPTER \h \r 1

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

Office of Chemical Safety

 and Pollution Prevention

MEMORANDUM

DATE:  	May 3, 2010

SUBJECT:	Thiamethoxam.  Acute and Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessments for the Section 3 Registration as a Seed Treatment on Onion, Dry Bulb, Removing the Geographical Limitations on the Foliar Treatment of Barley.

PC Code:  060109	DP Barcodes:  D373595/D375247

Decision Number:   415289	Registration Number:  100-1294

Petition Number: 9F7582	Regulatory Action:  Section 3

                                 Registration

Assessment Type:  Dietary	Case Number:  None

TXR Number:  None	CAS Number:  153719-23-4

MRID Number:  None	40CFR §180.565

REVIEWER:	Dennis McNeilly, Chemist

		Risk Assessment Branch II (RAB2)

Health Effects Division (HED), 7509P

THROUGH:	Amelia M. Acierto, Chemist

		Mohsen Sahafeyan, Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (HED), 7509P

TO:	Dennis McNeilly, Chemist

Risk Assessment Branch II (RAB2)/HED, 7509P

               &

		Julie Chao/Venus Eagle, Team 01

		Insecticide/Rodenticide Branch

		Registration Division (RD), 7505P

Executive Summary

n Model software with the Food Commodity Intake Database (DEEM-FCID™), Version 2.03, which uses food consumption data from the US Department of Agriculture’s Continuing Surveys of Food Intakes by Individuals (CSFII), collected from 1994 to 1996, and 1998.  These analyses were performed to support the Section 3 request for thiamethoxam use as a seed treatment for onion, dry bulb.  These analyses also support removing the current geographical use limitation for the foliar treatment of barley; as these assessments assume 100% crop treated for barley.

Tolerances for residues of thiamethoxam are listed in 40 CFR §180.565 and are expressed in terms of the combined residues of the insecticide thiamethoxam and its metabolite CGA-322704.  Thiamethoxam’s major metabolite is CGA-322704, which is also the registered active ingredient clothianidin.  Clothianidin has a complete toxicological database and appears to have effects in mammals that are different from those of thiamethoxam.  Nevertheless, in conducting these assessments, residues of clothianidin coming from thiamethoxam use were added to residues of thiamethoxam.  The total or combined residue was then used to estimate acute and chronic dietary exposure and risk.  Both the acute and chronic assessments assumed that 100% of crops were treated with registered or requested uses of thiamethoxam.  This assumption is highly conservative with respect to thiamethoxam use and obviates the need to include residues of clothianidin coming from clothianidin uses.  A new chlothianidin dietary assessment and risk assessment accounting for clothianidin residues on onion, dry bulb resulting from thiamethoxam application is not necessary, chlothianidin is already registered for use on Vegetable, bulb group 3-07, which includes onion, dry bulb (0.45 ppm tolerance).

The acute assessment is based on tolerance level residues of thiamethoxam/clothianidin (the tolerance is for combined residues).  The chronic analysis is based on tolerance level and/or average field trial (see D364256, D. McNeilly, June 30, 2009) residues and all assume 100% crop treated.  The assumption of 100% CT in these analyses (acute and chronic) results in a conservative assessment for thiamethoxam.  Clothianidin and thiamethoxam are not expected to be used on the same crop, as a recommendation against this appears on the end-use labels.  The analyses included direct incorporation of estimated thiamethoxam/clothianidin residues in drinking water.  For water, the highest estimate from conservative models was used for both the acute and the chronic dietary exposure analyses.

Based on these highly conservative assumptions, acute dietary risk estimates at the 95th percentile of exposure are less than or equal to 9.5% of the acute population-adjusted dose (aPAD) for all population subgroups.  Chronic dietary risk estimates are less than or equal to 42% of the chronic population-adjusted dose (cPAD) for all population subgroups.  Generally, HED is concerned when risk estimates exceed 100% of the PAD; therefore, all acute and chronic dietary risk estimates are below HED’s level of concern (LOC).

These analyses indicate that there are no dietary exposure considerations that would preclude registration of thiamethoxam for the requested use on dry bulb onions.

1.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (the dose which HED has concluded will result in no unreasonable adverse health effects).  This dose is referred to as the population adjusted dose (PAD).  The PAD is equivalent to the point of departure (POD), such as the NOAEL or LOAEL, divided by the requisite uncertainty and/or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References which discuss the acute and chronic risk assessments in more detail are available on the EPA pesticides web site, Available Information on Assessing Exposure from Pesticides, A User’s Guide (21 June 2000), which can be accessed via the web link http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf (or see SOP 99.6, dated 8/20/1999).

The most recent dietary risk assessment for thiamethoxam was conducted by D. McNeilly (D364256, 30 June 2009).  Table 3 in that review, provides the anticipated residues used in the chronic assessment.

Thiamethoxam is a member of the neonicotinoid class of pesticides and its major metabolite clothianidin is another neonicotinoid.  Structural similarities or common effects do not constitute a common mechanism of toxicity.  Although clothianidin and thiamethoxam bind selectively to insect nicotinic acetylcholine receptors (nAChR), the specific binding site(s)/receptor(s) for clothianidin, thiamethoxam, and the other neonicotinoids are unknown at this time.  Additionally, the commonality of the binding activity itself is uncertain, as preliminary evidence suggests that clothianidin operates by direct competitive inhibition, while thiamethoxam is a non-competitive inhibitor.  Furthermore, even if future research shows that neonicotinoids share a common binding activity to a specific site on insect nicotinic acetylcholine receptors, there is not necessarily a relationship between this pesticidal action and a mechanism of toxicity in mammals.  Structural variations between the insect and mammalian nAChRs produce quantitative differences in the binding affinity of the neonicotinoids towards these receptors, which, in turn, confers the notably greater selective toxicity of this class towards insects, including aphids and leafhoppers, compared to mammals.  While the insecticidal action of the neonicotinoids is neurotoxic, the most sensitive regulatory endpoint for clothianidin is based on unrelated effects in mammals, including changes in body and thymus weights, delays in sexual maturation, and still births.  Additionally, the most sensitive toxicological effect in mammals differs across the neonicotinoids (e.g., testicular tubular atrophy with thiamethoxam; mineralized particles in thyroid colloid with imidaclopid).  Thus, there is currently no evidence to indicate that neonicotinoids share common mechanisms of toxicity, and EPA is not following a cumulative risk approach based on a common mechanism of toxicity for the neonicotinoids.

2.	Residue Information

Tolerances have been established for both thiamethoxam (40CFR §180.565) and clothianidin (40CFR §180.586) on a variety of commodities.  This assessment includes residue estimates associated with the requested Section 3 registration of thiamethoxam on onions, dry bulb (see Table 1).  The residue of concern for this dietary risk assessment is thiamethoxan and its metabolite, clothianidin.

Table 1.    Tolerance Summary for Thiamethoxam Proposed Uses on Onions, dry bulb.

Commodity	Proposed Tolerance (ppm)	Recommended Tolerance (ppm)	Comments; Correct Commodity Definition

Tolerances Proposed under 180.565(a)

Onion, dry bulb	0.03	0.03	Onion, dry bulb

The estimates of residues in livestock commodities are as recommended in the recent thiamethoxam risk assessment (D348703, M. Doherty, 25 Sept 2008).

Empirical processing factors were used when available.  For food forms without empirical processing factors, DEEM 7.81 default values were used.  A complete listing of the processing factors used can be found in Table 3 of HED’s June 30, 2009 review for thiamethoxam (D364256, Dennis McNeilly).  A complete listing of the residues and processing factors used in the analyses are included in Attachments 1, and 2.

The chronic assessment makes use of average residue values from the thiamethoxam field trials for the selected commodities which are listed in HED’s last dietary analyses for thiomethoxam (D364256, D. McNeilly, 30 June 2009).   Although monitoring data are available for some commodities, field trial residues were used for all the uses, along with a high end estimate of drinking water residues.  Therefore this assessment is considered conservative.

3.	Drinking Water Data

The drinking water residues used in these dietary risk assessments were provided by EFED (D368072, C. Kopert, 2 February 2010), and incorporated directly into the dietary assessments.  Water residues were incorporated in DEEM-FCID via entry into the food categories “water, direct, all sources” and “water, indirect, all sources.”  The estimated drinking water concentrations (EDWCs) in surface water are 0.13177 ppm and 0.01131 ppm for acute and chronic scenarios, respectively.  Typically, HED uses the higher of the surface or groundwater estimates for each duration when assessing dietary risk, with the surface water having higher values in this case.

The EDWCs were incorporated into the acute and chronic thiamethoxam assessments.  Clothianidin, a major metabolite of thiamethoxam in plants and livestock, is not a significant degradate of thiamethoxam in surface or groundwater sources of drinking water.

A Tier II screening-level drinking water assessment was conducted for the proposed seed treatment of dry bulb onions.  EFED also evaluated carrots, leafy vegetables and Brassica (cole) leafy vegetables because previous assessments on these commodities were conducted at a lower application rate.

For surface water, the EDWCs for the crops modeled in this assessment did not exceed the previous EDWCs for rice reported in the previous drinking water assessment (D363202, F. Khan, 07 April 2009). The reported acute concentration of 131.77 µg/L, annual mean (chronic) concentration of 11.31 µg/L and the highest 30 year annual average concentration of 11.31 µg/L from the rice model are higher than the reported EDWCs for various uses in Table 2.  Therefore, the current EDWCs for surface water do not supersede the drinking water concentrations previously estimated for this chemical (D363202).

For groundwater, based on the proposed highest annual use rate for leafy vegetables, the SCI-GROW model concentration of thiamethoxam was 3.42 µg/L.  This value was compared to 7.94 µg/L reported for grapes in an earlier drinking water assessment (D329467) dated 10 January 2007.  However, further review of this assessment revealed that the aerobic soil metabolism half-life input value was incorrect causing an incorrect groundwater EDWC value.  The 90th upper percentile on the mean was used instead of the mean half-life value.  Given that there were less than four half-life values in the data set, the value was re-calculated based on the mean half-life value, as specified in the SCI-GROW input guidance embedded within the model.  The correct EDWC is 4.14 µg/L.  Since 3.42 µg/L is less than 4.14 µg/L, the current EDWC does not supersede the recalculated estimated drinking water concentration for groundwater.

The acute scenario EDWC in surface water (0.13177 ppm) was obtained via exposure modeling which utilized the FIRST (FQPA Index Reservoir Screening Tool) model.  This model and its description are available at the EPA internet website via the web link,   HYPERLINK "http://www.epa.gov/oppefed1/models/water/"  http://www.epa.gov/oppefed1/models/water/ .

Table 2. Tier II Estimated Drinking Water Concentrations (EDWCs) resulting from applications of Thiamethoxam.

Drinking Water Source (model)	Use

Scenario

(modeled rate)	1-in-10 year acute (µg/L)	1-in-10 year chronic (µg/L) 30- year average (µg/L)

Surface Water (PRZM/EXAMS)	Dry Bulb Onions:

CA Onion

GA Onion

(1 app. X 0.18 lbs ai/acre)

0.94

12.25

0.15

0.92

0.03

0.26

	Carrots:

FL Carrots

(1 app. X 0.22 lbs ai/acre)

9.25

0.53

0.36

	Brassica (Cole) Leafy Vegs:

CA Cole Crop

(1 app. X 0.22 lbs ai/acre)

7.90

1.06

0.44

	Leafy Vegetables:

CA Lettuce (1 run)

(2 app. X 0.133 lbs. ai/acre)

CA Lettuce (2 runs)

(1 app. X 0.133 lbs. ai/acre)

(1 app. X 0.133 lbs. ai/acre)

12.19

11.85

5.86

2.07

1.84

0.71

1.03

0.64

0.39

Tail water

	Rice

(0.173 lbs ai/A/year)	131.771,2	11.311,3	11.311,3

	Cranberry

(0.188 lbs ai/A/year)	54.752	4.503	4.503

Groundwater

(SCI-GROW)	Leafy Vegetables:

(0.22 lbs a.i./acre)

3.42

3.42

3.42

	Grape

(0.266 lb ai/A)	4.14	4.14	4.14

Bold text denotes maximum estimated EDWC values.  All values adjusted with PCA factor of 0.87.

1 = Recommended EDWCs for surface water

2 = EDWCs based on day 1

3 = EDWCs based on average of 365days

Monitoring Data

Two small-scale prospective groundwater (PGW) monitoring studies were initiated in southwest Michigan in June 2001 and southwestern Georgia in the spring of 2002, to determine the potential for the active ingredient thiamethoxam and its degradates to reach groundwater when used in a vulnerable hydrogeologic setting. Analytical data were collected for 47 months (from  treatment in the spring of 2001 until May 2005) in the Michigan study and for 36 months (from treatment in the spring of 2002 until May 2005) in the Georgia study.  The monitoring data demonstrate that concentrations of the analytes of interest have peaked in the groundwater and have either completely dissipated or have leveled off for an extended period of time.

In Michigan, thiamethoxam residues found in soil-pore water samples have clearly peaked and then declined. No quantifiable residues of thiamethoxam > LOQ (0.05 ppb) were observed in any of the 3, 6, and 9-ft lysimeters after the 36, 16, and 41-MAT sampling events, respectively. By the 47-MAT sampling event only trace level detections of thiamethoxam were observed in three of the 15-ft. lysimeter units (maximum concentration 0.11 ppb).

In Georgia, thiamethoxam residues have only been confirmed in four shallow monitoring wells (MW-1S, MW-3S, MW-5S, and MW-8S) during 47 months of sampling. Thiamethoxam residues in groundwater peaked at 43-MAT, and by 47-MAT residues were confined to two shallow monitoring wells only (maximum concentration 0.12 ppb). No detections of thiamethoxam at or greater than the analytical method LOQ have been observed in any groundwater samples collected from the deep monitoring wells during 47 months of sampling.

4.	DEEM-FCID™ Program and Consumption Information

Thiamethoxam acute and chronic dietary exposure assessments were conducted using DEEM-FCID™ (Version 2.03), which incorporates consumption data from USDA’s CSFII, 1994 to 1996, and 1998.  The 1994-96, 1998 data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods “as consumed” (such as apple pie) are linked to EPA-defined food commodities (such as apples, peeled fruit - cooked, fresh/unspecified, or baked; or wheat flour - cooked, fresh/unspecified, or baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  For chronic exposure assessment, consumption data are averaged for the entire US population, and within population subgroups, but for acute exposure assessment, they are retained as individual consumption events (which is why it is appropriate to add residue values together for the acute assessment, while separate exposure estimates are summed for the chronic assessment).  Based on analysis of the 1994-96, 1998 CSFII consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general US population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or food-form (such as orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form.  The resulting residue consumption estimate for each food/food form is summed with the residue consumption estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day, and as a percent of the cPAD.  This procedure is performed for each population subgroup.

For acute exposure assessments, individual one-day food consumption data are used on an individual-by-individual basis.  The reported consumption amounts of each food item can be multiplied by a residue point estimate, and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple random pairings with residue values, and then summed in a probabilistic assessment.  The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (those who reported eating relevant commodities/food forms) and a per-capita (those who reported eating the relevant commodities as well as those who did not) basis.  In accordance with HED policy, per capita exposure and risk are reported for all tiers of analysis.  However, for Tiers 1 and 2, significant differences in user versus per capita exposure and risk are identified, and noted in the risk assessment.

5.	Toxicological Information

The toxicology database for thiamethoxam is complete.  The scientific quality is relatively high and the toxicity profile of thiamethoxam can be characterized for most effects, including potential carcinogenic, mutagenic, developmental, and neurotoxic effects.

It is recommended that the 10X FQPA safety factor for the protection of infants and children be reduced to 1X.  There is no quantitative or qualitative evidence of increased susceptibility of rat or rabbit fetuses to in utero exposure to thiamethoxam in the developmental toxicity studies.  The developmental NOAELs are either higher than or equal to the maternal NOAELs.  The Developmental Neurotoxity (DNT) Workgroup concluded there was no evidence of increased quantitative susceptibility in the DNT study in rats, based on evaluation of additional brain morphometric data for the low- and mid-dose pups (January 17, 2007 meeting).

Although there is evidence of increased quantitative susceptibility for male pups of both two generation reproductive studies, NOAELs and LOAELs were established in these studies, and the Agency selected the NOAEL for testicular effects in F1 pups as the basis for risk assessment.  The Agency is confident that the NOAEL selected for risk assessment is protective of the most sensitive effect (testicular effects) for the most sensitive subgroup (pups) observed in the toxicological database.

In addition, the NOAELs selected for risk assessment are protective of all toxicological effects observed in the database including treatment-related changes in the adrenal gland, thyroid, testes and ovaries.  Thus, the Agency believes the FQPA safety factor can be reduced to 1X and still be conservatively protective of human health risk.

Table 3.  Toxicological Doses and Endpoints for Thiomethoxam for Use in Human Health Risk Assessments.

Exposure/

Scenario	Point of Departure	Uncertainty/ FQPA Safety Factors	Level of Concern for Risk Assessment	Study and Toxicological Effects

Acute Dietary

All populations including infants and children 	NOAEL =  34.5 mg/kg/day

	UFA= 10x

UFH= 10x

SFFQPA=1

 	aRfD=0.35 mg/kg/day

aPAD=0.35 mg/kg/day	Rat Developmental Neurotoxicity study

LOAEL = 298.7 mg/kg/day based on delayed sexual maturation in male pups, and reduced brain morphometric measurements.

Chronic Dietary

All populations including infants and children	NOAEL= 1.2 mg/kg/day

(MRID 46402904) 	UFA= 10x

UFH= 10x

SFFQPA=1

	cRfD=0.012 mg/kg/day

cPAD=0.012 mg/kg/day	2-Generation reproduction study

LOAEL = 1.8 mg/kg/day based on increased incidence and severity of tubular atrophy in testes of F1 generation males.

2-Generation reproduction study (46402904)

LOAEL = 3 (males), not determined (females) mg/kg/day based on sperm abnormalities in F1 males.

Cancer (oral, dermal, inhalation)	“Not Likely to be Carcinogenic to Humans” based on convincing evidence that a non-genotoxic mode of action for liver tumors was established in the mouse and that the carcinogenic effects are a result of a mode of action dependent on sufficient amounts of a hepatotoxic metabolite produced persistently.  Quantification of cancer risk is not required.

6.	Results/Discussion

As previously stated, for acute and chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD.  The DEEM-FCID™ analyses estimate the dietary exposure of the US population and various population subgroups.

Table 4.  Summary of Estimated Dietary (Food + Drinking Water) Exposures and Risk for Thiamethoxam.

Population Subgroup	aPAD, mg/kg	Acute Estimates (95th Percentile)	cPAD, mg/kg/day	Chronic Estimates

Exposure, mg/kg	Risk, % aPAD

Exposure, mg/kg/day	Risk, % cPAD

U.S. Population	0.35	0.018088	5.2	0.012	0.002795	23

All infants (< 1 year)	0.35	0.033163	9.5	0.012	0.003002	25

Children 1-2 yrs	0.35	0.032980	9.4	0.012	0.005065	42

Children 3-5 yrs	0.35	0.026607	7.6	0.012	0.004446	37

Children 6-12 yrs	0.35	0.018827	5.4	0.012	0.003196	27

Youth 13-19 yrs	0.35	0.014308	4.1	0.012	0.002308	19

Adults 20-49 yrs	0.35	0.016273	4.7	0.012	0.002567	21

Adults 50+ yrs	0.35	0.016610	4.8	0.012	0.002625	22

Females 13-49 yrs	0.35	0.016146	4.6	0.012	0.002595	22

The population subgroup with the highest estimated exposure/risk is bolded.

oncerned when dietary risk exceeds 100% of the PAD.  The DEEM-FCID™ analyses estimate the dietary exposure of the U.S. population and various population subgroups.  The results reported in Table 6 are for the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50+ years.  The acute results summarized in Table 6 are for the 95th percentile of exposure.  A complete listing of acute and chronic exposure and risk estimates can be found in Attachments 2 and 3, respectively.

The analyses indicate that the requested uses of thiamethoxam, coupled with currently registered uses, will result in acute and chronic dietary (food + drinking water) exposures that are below HED’s level of concern for all population subgroups, including those of infants and children.

Typically, HED uses tolerance-level residues in its most conservative assessments.  For this reason, the acute assessment is considered to be an unrefined assessment (i.e., screening level) and evaluation at the 95th percentile of exposure is appropriate.  The acute assessment indicates that All Infants are the most highly-exposed subgroup, utilizing 9.5% of the aPAD, while the general US population utilizes 5.2% of the aPAD; all risk estimates are below HED’s level of concern (Table 6).  Similarly, risk estimates for the chronic dietary exposure analysis are below HED’s level of concern, with Children 1-2 years being the most highly-exposed subgroup, utilizing 42% of the chronic population-adjusted dose (cPAD), while the general U.S. population utilizes 23% of the cPAD.

7.	Characterization of Inputs/Outputs

This assessment is based on tolerance level or field trial residues and assumes 100% CT.  The exposure values represent high-end estimates and should be considered highly conservative, health-protective estimates of dietary exposure and risk.  The Tier I Rice Model used to generate the EDWCs is expected to generate conservative estimates that exceed peak measured concentrations of pesticides in water bodies well downstream of rice paddies by less than one order of magnitude to multiple orders of magnitude.

8.	Conclusions

Based on highly conservative assumptions, there are no dietary (food + drinking water) exposure considerations that would preclude registration of thiamethoxam on onion, dry bulb.  These analyses also support removing the geographical use limitation for the foliar treatment of barley; as these assessments assume 100% crop treated for barley.

9.	List of Attachments

Attachment 1.  Input file for the acute dietary exposure analyses of thiamethoxam.

Attachment 2.  Input file for the chronic dietary exposure analyses of thiamethoxam.

Attachment 3.  Summary of the acute dietary exposure analysis for thiamethoxam.

Attachment 4.  Summary of the chronic dietary exposure analysis for thiamethoxam.

Attachment 1.	Input File for the Acute Dietary Exposure Estimates.

U.S. Environmental Protection Agency                                 Ver. 2.02

DEEM-FCID Acute analysis for THIAMETHOXAM

Residue file name: C:\Documents and Settings\dmcneill\My Documents\Thiamethoxam\060109 2010 Acute T+Water.R98

Analysis Date 03-04-2010             Residue file dated: 03-04-2010/14:31:37/8

Reference dose (aRfD) = 0.35 mg/kg bw/day

Comment: Acute and Chronic RfDs = aPAD and cPAD

------------------------------------------------------------------------ --------

  EPA    Crop                                   Def Res     Adj.Factors   Comment

  Code    Grp  Food Name                         (ppm)       #1    #2

-------- ---- -------------------------------  ----------  ------ ------  -------

14000030 14   Almond                             0.020000   1.000  1.000

14000031 14   Almond-babyfood                    0.020000   1.000  1.000

14000040 14   Almond, oil                        0.020000   1.000  1.000

14000041 14   Almond, oil-babyfood               0.020000   1.000  1.000

04010050 4A   Amaranth, leafy                    4.000000   1.000  1.000

11000070 11   Apple, fruit with peel             0.200000   1.000  1.000

11000080 11   Apple, peeled fruit                0.200000   1.000  1.000

11000081 11   Apple, peeled fruit-babyfood       0.200000   1.000  1.000

11000090 11   Apple, dried                       0.200000   8.000  1.000

11000091 11   Apple, dried-babyfood              0.200000   8.000  1.000

11000100 11   Apple, juice                       0.200000   0.750  1.000

11000101 11   Apple, juice-babyfood              0.200000   0.750  1.000

11000110 11   Apple, sauce                       0.200000   1.000  1.000

11000111 11   Apple, sauce-babyfood              0.200000   1.000  1.000

12000120 12   Apricot                            0.500000   1.000  1.000

12000121 12   Apricot-babyfood                   0.500000   1.000  1.000

12000130 12   Apricot, dried                     0.500000   6.000  1.000

12000140 12   Apricot, juice                     0.500000   1.000  1.000

12000141 12   Apricot, juice-babyfood            0.500000   1.000  1.000

95000160 O    Artichoke, globe                   0.450000   1.000  1.000

04010180 4A   Arugula                            4.000000   1.000  1.000

95000200 O    Avocado                            0.400000   1.000  1.000

09020210 9B   Balsam pear                        0.200000   1.000  1.000

15000250 15   Barley, pearled barley             0.300000   0.300  1.000D28170

          Full comment: D281702

15000251 15   Barley, pearled barley-babyfood    0.300000   0.300  1.000D28170

          Full comment: D281702

15000260 15   Barley, flour                      0.300000   0.100  1.000D28170

          Full comment: D281702

15000261 15   Barley, flour-babyfood             0.300000   0.100  1.000D28170

          Full comment: D281702

15000270 15   Barley, bran                       0.300000   0.300  1.000D28170

          Full comment: D281702

06030300 6C   Bean, black, seed                  0.020000   1.000  1.000

06020310 6B   Bean, broad, succulent             0.020000   1.000  1.000

06030320 6C   Bean, broad, seed                  0.020000   1.000  1.000

06020330 6B   Bean, cowpea, succulent            0.020000   1.000  1.000

06030340 6C   Bean, cowpea, seed                 0.020000   1.000  1.000

06030350 6C   Bean,  great northern, seed        0.020000   1.000  1.000

06030360 6C   Bean, kidney, seed                 0.020000   1.000  1.000

06020370 6B   Bean, lima, succulent              0.020000   1.000  1.000

06030380 6C   Bean, lima, seed                   0.020000   1.000  1.000

06030390 6C   Bean, mung, seed                   0.020000   1.000  1.000

06030400 6C   Bean, navy, seed                   0.020000   1.000  1.000

06030410 6C   Bean, pink, seed                   0.020000   1.000  1.000

06030420 6C   Bean, pinto, seed                  0.020000   1.000  1.000

06010430 6A   Bean, snap, succulent              0.020000   1.000  1.000

06010431 6A   Bean, snap, succulent-babyfood     0.020000   1.000  1.000

21000440 M    Beef, meat                         0.020000   1.000  1.000

21000441 M    Beef, meat-babyfood                0.020000   1.000  1.000

21000450 M    Beef, meat, dried                  0.020000   1.920  1.000

21000460 M    Beef, meat byproducts              0.040000   1.000  1.000

21000461 M    Beef, meat byproducts-babyfood     0.040000   1.000  1.000

21000480 M    Beef, kidney                       0.040000   1.000  1.000

21000490 M    Beef, liver                        0.040000   1.000  1.000

21000491 M    Beef, liver-babyfood               0.040000   1.000  1.000

01010500 1AB  Beet, garden, roots                0.050000   1.000  1.000D35744

          Full comment: D357449, recommended tol.

01010501 1AB  Beet, garden, roots-babyfood       0.050000   1.000  1.000

01010520 1A   Beet, sugar                        0.050000   1.000  1.000

01010521 1A   Beet, sugar-babyfood               0.050000   1.000  1.000

01010530 1A   Beet, sugar, molasses              0.050000   1.000  1.000

01010531 1A   Beet, sugar, molasses-babyfood     0.050000   1.000  1.000

13010550 13A  Blackberry                         0.350000   1.000  1.000

13010560 13A  Blackberry, juice                  0.350000   1.000  1.000

13010561 13A  Blackberry, juice-babyfood         0.350000   1.000  1.000

13020570 13B  Blueberry                          0.300000   1.000  1.000

13020571 13B  Blueberry-babyfood                 0.300000   1.000  1.000

13010580 13A  Boysenberry                        0.350000   1.000  1.000

14000590 14   Brazil nut                         0.020000   1.000  1.000

05010610 5A   Broccoli                           4.500000   1.000  1.000

05010611 5A   Broccoli-babyfood                  4.500000   1.000  1.000

05010620 5A   Broccoli, Chinese                  4.500000   1.000  1.000

05020630 5B   Broccoli raab                      3.000000   1.000  1.000

05010640 5A   Brussels sprouts                   4.500000   1.000  1.000

15000650 15   Buckwheat                          0.020000   1.000  1.000

15000660 15   Buckwheat, flour                   0.020000   1.000  1.000

01010670 1AB  Burdock                            0.050000   1.000  1.000

14000680 14   Butternut                          0.020000   1.000  1.000

05010690 5A   Cabbage                            4.500000   1.000  1.000

05020700 5B   Cabbage, Chinese, bok choy         3.000000   1.000  1.000

05010710 5A   Cabbage, Chinese, napa             4.500000   1.000  1.000

05010720 5A   Cabbage, Chinese, mustard          4.500000   1.000  1.000

95000740 O    Canistel                           0.400000   1.000  1.000

09010750 9A   Cantaloupe                         0.200000   1.000  1.000

04020760 4B   Cardoon                            4.000000   1.000  1.000

01010780 1AB  Carrot                             0.050000   1.000  1.000

01010781 1AB  Carrot-babyfood                    0.050000   1.000  1.000

01010790 1AB  Carrot, juice                      0.050000   1.000  1.000

09010800 9A   Casaba                             0.200000   1.000  1.000

14000810 14   Cashew                             0.020000   1.000  1.000

05010830 5A   Cauliflower                        4.500000   1.000  1.000

01010840 1AB  Celeriac                           0.050000   1.000  1.000

04020850 4B   Celery                             4.000000   1.000  1.000

04020851 4B   Celery-babyfood                    4.000000   1.000  1.000

04020860 4B   Celery, juice                      4.000000   1.000  1.000

04020870 4B   Celtuce                            4.000000   1.000  1.000

09020880 9B   Chayote, fruit                     0.200000   1.000  1.000

95000890 O    Cherimoya                          0.110000   1.000  1.000

12000900 12   Cherry                             0.500000   1.000  1.000

12000901 12   Cherry-babyfood                    0.500000   1.000  1.000

12000910 12   Cherry, juice                      0.500000   1.500  1.000

12000911 12   Cherry, juice-babyfood             0.500000   1.500  1.000

14000920 14   Chestnut                           0.020000   1.000  1.000

06030980 6C   Chickpea, seed                     0.020000   1.000  1.000

06030981 6C   Chickpea, seed-babyfood            0.020000   1.000  1.000

06030990 6C   Chickpea, flour                    0.020000   1.000  1.000

01011000 1AB  Chicory, roots                     0.050000   1.000  1.000

09021020 9B   Chinese waxgourd                   0.200000   1.000  1.000

04011040 4A   Chrysanthemum, garland             4.000000   1.000  1.000

10001060 10   Citrus citron                      0.400000   1.000  1.000D34870

          Full comment: D348703

10001070 10   Citrus hybrids                     0.400000   1.000  1.000

10001080 10   Citrus, oil                        0.400000   0.600  1.000D34927

          Full comment: D349272

95001150 O    Coffee, roasted bean               0.050000   1.000  1.000

95001160 O    Coffee, instant                    0.050000   1.000  1.000

05021170 5B   Collards                           3.000000   1.000  1.000

15001200 15   Corn, field, flour                 0.020000   1.000  1.000

15001201 15   Corn, field, flour-babyfood        0.020000   1.000  1.000

15001210 15   Corn, field, meal                  0.020000   1.000  1.000

15001211 15   Corn, field, meal-babyfood         0.020000   1.000  1.000

15001220 15   Corn, field, bran                  0.020000   1.000  1.000

15001230 15   Corn, field, starch                0.020000   1.000  1.000

15001231 15   Corn, field, starch-babyfood       0.020000   1.000  1.000

15001240 15   Corn, field, syrup                 0.020000   1.500  1.000

15001241 15   Corn, field, syrup-babyfood        0.020000   1.500  1.000

15001250 15   Corn, field, oil                   0.020000   1.000  1.000

15001251 15   Corn, field, oil-babyfood          0.020000   1.000  1.000

15001260 15   Corn, pop                          0.020000   1.000  1.000

15001270 15   Corn, sweet                        0.020000   1.000  1.000

15001271 15   Corn, sweet-babyfood               0.020000   1.000  1.000

95001280 O    Cottonseed, oil                    0.100000   1.000  1.000

95001281 O    Cottonseed, oil-babyfood           0.100000   1.000  1.000

11001290 11   Crabapple                          0.200000   1.000  1.000

95001300 O    Cranberry                          0.020000   1.000  1.000

95001301 O    Cranberry-babyfood                 0.020000   1.000  1.000

95001310 O    Cranberry, dried                   0.020000   1.000  1.000

95001320 O    Cranberry, juice                   0.020000   1.100  1.000

95001321 O    Cranberry, juice-babyfood          0.020000   1.100  1.000

04011330 4A   Cress, garden                      4.000000   1.000  1.000

04011340 4A   Cress, upland                      4.000000   1.000  1.000

09021350 9B   Cucumber                           0.200000   1.000  1.000

13021360 13B  Currant                            0.200000   1.000  1.000

13021370 13B  Currant, dried                     0.200000   1.000  1.000

04011380 4A   Dandelion, leaves                  4.000000   1.000  1.000

13011420 13A  Dewberry                           0.350000   1.000  1.000

08001480 8    Eggplant                           0.250000   1.000  1.000

13021490 13B  Elderberry                         0.200000   1.000  1.000

04011500 4A   Endive                             4.000000   1.000  1.000

04021520 4B   Fennel, Florence                   4.000000   1.000  1.000

14001550 14   Filbert                            0.020000   1.000  1.000

14001560 14   Filbert, oil                       0.020000   1.000  1.000

20001630 20   Flaxseed, oil                      0.020000   1.000  1.000

01011680 1AB  Ginseng, dried                     0.050000   1.000  1.000

23001690 M    Goat, meat                         0.020000   1.000  1.000

23001700 M    Goat, meat byproducts              0.040000   1.000  1.000

23001720 M    Goat, kidney                       0.040000   1.000  1.000

23001730 M    Goat, liver                        0.040000   1.000  1.000

13021740 13B  Gooseberry                         0.200000   1.000  1.000

95001750 O    Grape                              0.200000   1.000  1.000

95001760 O    Grape, juice                       0.200000   1.100  1.000D28170

          Full comment: D281702

95001761 O    Grape, juice-babyfood              0.200000   1.100  1.000

95001770 O    Grape, leaves                      0.200000   1.000  1.000

95001780 O    Grape, raisin                      0.200000   2.300  1.000D28170

          Full comment: D281702

95001790 O    Grape, wine and sherry             0.200000   1.000  1.000

10001800 10   Grapefruit                         0.400000   1.000  1.000

10001810 10   Grapefruit, juice                  0.400000   0.600  1.000D34927

          Full comment: D349272

06031820 6C   Guar, seed                         0.020000   1.000  1.000

06031821 6C   Guar, seed-babyfood                0.020000   1.000  1.000

14001850 14   Hickory nut                        0.020000   1.000  1.000

09011870 9A   Honeydew melon                     0.200000   1.000  1.000

95001880 O    Hop                                0.100000   1.000  1.000

24001890 M    Horse, meat                        0.020000   1.000  1.000

01011900 1AB  Horseradish                        0.050000   1.000  1.000

13021910 13B  Huckleberry                        0.200000   1.000  1.000

05021940 5B   Kale                               3.000000   1.000  1.000

05011960 5A   Kohlrabi                           4.500000   1.000  1.000

10001970 10   Kumquat                            0.400000   1.000  1.000

10001990 10   Lemon                              0.400000   1.000  1.000

10002000 10   Lemon, juice                       0.400000   0.600  1.000D34827

          Full comment: D348272

10002001 10   Lemon, juice-babyfood              0.400000   0.600  1.000D34927

          Full comment: D349272

10002010 10   Lemon, peel                        0.400000   1.000  1.000

06032030 6C   Lentil, seed                       0.020000   1.000  1.000

04012040 4A   Lettuce, head                      4.000000   1.000  1.000

04012050 4A   Lettuce, leaf                      4.000000   1.000  1.000

10002060 10   Lime                               0.400000   1.000  1.000

10002070 10   Lime, juice                        0.400000   0.600  1.000D34827

          Full comment: D348272

10002071 10   Lime, juice-babyfood               0.400000   0.600  1.000D34927

          Full comment: D349272

13012080 13A  Loganberry                         0.350000   1.000  1.000

11002100 11   Loquat                             0.200000   1.000  1.000

14002130 14   Macadamia nut                      0.020000   1.000  1.000

95002150 O    Mango                              0.400000   1.000  1.000

95002151 O    Mango-babyfood                     0.400000   1.000  1.000

95002160 O    Mango, dried                       0.400000   1.000  1.000

95002170 O    Mango, juice                       0.400000   1.000  1.000

95002171 O    Mango, juice-babyfood              0.400000   1.000  1.000

28002210 M    Meat, game                         0.020000   1.000  1.000

27002220 D    Milk, fat                          0.020000   1.000  1.000

27002221 D    Milk, fat - baby food/infant for   0.020000   1.000  1.000

27012230 D    Milk, nonfat solids                0.020000   1.000  1.000

27012231 D    Milk, nonfat solids-baby food/in   0.020000   1.000  1.000

27022240 D    Milk, water                        0.020000   1.000  1.000

27022241 D    Milk, water-babyfood/infant form   0.020000   1.000  1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.020000   1.000  1.000

15002260 15   Millet, grain                      0.020000   1.000  1.000

05022290 5B   Mustard greens                     3.000000   1.000  1.000

12002300 12   Nectarine                          0.500000   1.000  1.000

15002310 15   Oat, bran                          0.020000   1.000  1.000

15002320 15   Oat, flour                         0.020000   1.000  1.000

15002321 15   Oat, flour-babyfood                0.020000   1.000  1.000

15002330 15   Oat, groats/rolled oats            0.020000   1.000  1.000

15002331 15   Oat, groats/rolled oats-babyfood   0.020000   1.000  1.000

08002340 8    Okra                               0.250000   1.000  1.000

03002370 3    Onion, dry bulb                    0.030000   1.000  1.000

03002371 3    Onion, dry bulb-babyfood           0.030000   1.000  1.000

03002380 3    Onion, dry bulb, dried             0.030000   9.000  1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.030000   9.000  1.000

10002400 10   Orange                             0.400000   1.000  1.000

10002410 10   Orange, juice                      0.400000   0.600  1.000D34927

          Full comment: D349272

10002411 10   Orange, juice-babyfood             0.400000   0.600  1.000D34827

          Full comment: D348272

10002420 10   Orange, peel                       0.400000   1.000  1.000

95002450 O    Papaya                             0.400000   1.000  1.000

95002451 O    Papaya-babyfood                    0.400000   1.000  1.000

95002460 O    Papaya, dried                      0.400000   1.800  1.000

95002470 O    Papaya, juice                      0.400000   1.500  1.000

04012480 4A   Parsley, leaves                    4.000000   1.000  1.000

01012500 1AB  Parsley, turnip rooted             0.050000   1.000  1.000

01012510 1AB  Parsnip                            0.050000   1.000  1.000

01012511 1AB  Parsnip-babyfood                   0.050000   1.000  1.000

06022550 6B   Pea, succulent                     0.020000   1.000  1.000

06022551 6B   Pea, succulent-babyfood            0.020000   1.000  1.000

06032560 6C   Pea, dry                           0.020000   1.000  1.000

06032561 6C   Pea, dry-babyfood                  0.020000   1.000  1.000

06012570 6A   Pea, edible podded, succulent      0.020000   1.000  1.000

06032580 6C   Pea, pigeon, seed                  0.020000   1.000  1.000

06022590 6B   Pea, pigeon, succulent             0.020000   1.000  1.000

12002600 12   Peach                              0.500000   1.000  1.000

12002601 12   Peach-babyfood                     0.500000   1.000  1.000

12002610 12   Peach, dried                       0.500000   7.000  1.000

12002611 12   Peach, dried-babyfood              0.500000   7.000  1.000

12002620 12   Peach, juice                       0.500000   1.000  1.000

12002621 12   Peach, juice-babyfood              0.500000   1.000  1.000

11002660 11   Pear                               0.200000   1.000  1.000

11002661 11   Pear-babyfood                      0.200000   1.000  1.000

11002670 11   Pear, dried                        0.200000   6.250  1.000

11002680 11   Pear, juice                        0.200000   1.000  1.000

11002681 11   Pear, juice-babyfood               0.200000   1.000  1.000

14002690 14   Pecan                              0.020000   1.000  1.000

08002700 8    Pepper, bell                       0.250000   1.000  1.000

08002701 8    Pepper, bell-babyfood              0.250000   1.000  1.000

08002710 8    Pepper, bell, dried                0.250000   1.000  1.000

08002711 8    Pepper, bell, dried-babyfood       0.250000   1.000  1.000

08002720 8    Pepper, nonbell                    0.250000   1.000  1.000

08002721 8    Pepper, nonbell-babyfood           0.250000   1.000  1.000

08002730 8    Pepper, nonbell, dried             0.250000   1.000  1.000

95002750 O    Peppermint                         1.500000   1.000  1.000

95002760 O    Peppermint, oil                    1.500000   0.050  1.000

14002820 14   Pistachio                          0.020000   1.000  1.000

12002850 12   Plum                               0.500000   1.000  1.000

12002851 12   Plum-babyfood                      0.500000   1.000  1.000

12002860 12   Plum, prune, fresh                 0.500000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood        0.500000   1.000  1.000

12002870 12   Plum, prune, dried                 0.500000   5.000  1.000

12002871 12   Plum, prune, dried-babyfood        0.500000   5.000  1.000

12002880 12   Plum, prune, juice                 0.500000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood        0.500000   1.400  1.000

25002900 M    Pork, meat                         0.020000   1.000  1.000

25002901 M    Pork, meat-babyfood                0.020000   1.000  1.000

25002920 M    Pork, meat byproducts              0.020000   1.000  1.000

25002921 M    Pork, meat byproducts-babyfood     0.020000   1.000  1.000

25002940 M    Pork, kidney                       0.020000   1.000  1.000

25002950 M    Pork, liver                        0.020000   1.000  1.000

01032960 1C   Potato, chips                      0.250000   1.200  1.000

01032970 1C   Potato, dry (granules/ flakes)     0.250000   1.700  1.000

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   1.700  1.000

01032980 1C   Potato, flour                      0.250000   1.700  1.000

01032981 1C   Potato, flour-babyfood             0.250000   1.700  1.000

01032990 1C   Potato, tuber, w/peel              0.250000   1.000  1.000

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000  1.000

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000  1.000

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000  1.000

10003070 10   Pummelo                            0.400000   1.000  1.000

09023080 9B   Pumpkin                            0.200000   1.000  1.000

09023090 9B   Pumpkin, seed                      0.200000   1.000  1.000

11003100 11   Quince                             0.200000   1.000  1.000

29003120 M    Rabbit, meat                       0.020000   1.000  1.000

04013130 4A   Radicchio                          4.000000   1.000  1.000

01013140 1AB  Radish, roots                      0.050000   1.000  1.000

02003150 2    Radish, tops                       0.800000   1.000  1.000

01013160 1AB  Radish, Oriental, roots            0.050000   1.000  1.000

02003170 2    Radish, Oriental, tops             0.800000   1.000  1.000

05023180 5B   Rape greens                        3.000000   1.000  1.000

20003190 20   Rapeseed, oil                      0.020000   1.000  1.000

20003191 20   Rapeseed, oil-babyfood             0.020000   1.000  1.000

13013200 13A  Raspberry                          0.350000   1.000  1.000

13013201 13A  Raspberry-babyfood                 0.350000   1.000  1.000

13013210 13A  Raspberry, juice                   0.350000   1.000  1.000

13013211 13A  Raspberry, juice-babyfood          0.350000   1.000  1.000

04023220 4B   Rhubarb                            4.000000   1.000  1.000

15003230 15   Rice, white                        0.020000   1.000  1.000

15003231 15   Rice, white-babyfood               0.020000   1.000  1.000

15003240 15   Rice, brown                        0.020000   1.000  1.000

15003241 15   Rice, brown-babyfood               0.020000   1.000  1.000

15003250 15   Rice, flour                        0.020000   1.000  1.000

15003251 15   Rice, flour-babyfood               0.020000   1.000  1.000

15003260 15   Rice, bran                         0.020000   0.900  1.000D35744

          Full comment: D357449

15003261 15   Rice, bran-babyfood                0.020000   0.900  1.000D35744

          Full comment: D357449

01013270 1AB  Rutabaga                           0.050000   1.000  1.000

15003280 15   Rye, grain                         0.020000   1.000  1.000

15003290 15   Rye, flour                         0.020000   1.000  1.000

20003300 20   Safflower, oil                     0.020000   1.000  1.000

20003301 20   Safflower, oil-babyfood            0.020000   1.000  1.000

01013310 1AB  Salsify, roots                     0.050000   1.000  1.000

95003330 O    Sapote, Mamey                      0.400000   1.000  1.000

26003390 M    Sheep, meat                        0.020000   1.000  1.000

26003391 M    Sheep, meat-babyfood               0.020000   1.000  1.000

26003400 M    Sheep, meat byproducts             0.040000   1.000  1.000

26003420 M    Sheep, kidney                      0.040000   1.000  1.000

26003430 M    Sheep, liver                       0.040000   1.000  1.000

15003440 15   Sorghum, grain                     0.020000   1.000  1.000

15003450 15   Sorghum, syrup                     0.020000   1.000  1.000

06003470 6    Soybean, seed                      0.020000   1.000  1.000

06003480 6    Soybean, flour                     0.020000   1.000  1.000

06003481 6    Soybean, flour-babyfood            0.020000   1.000  1.000

06003490 6    Soybean, soy milk                  0.020000   1.000  1.000

06003491 6    Soybean, soy milk-babyfood or in   0.020000   1.000  1.000

06003500 6    Soybean, oil                       0.020000   1.000  1.000

06003501 6    Soybean, oil-babyfood              0.020000   1.000  1.000

95003520 O    Spearmint                          1.500000   1.000  1.000

95003530 O    Spearmint, oil                     1.500000   0.050  1.000D28170

          Full comment: D281702

04013550 4A   Spinach                            4.000000   1.000  1.000

04013551 4A   Spinach-babyfood                   4.000000   1.000  1.000

09023560 9B   Squash, summer                     0.200000   1.000  1.000

09023561 9B   Squash, summer-babyfood            0.200000   1.000  1.000

09023570 9B   Squash, winter                     0.200000   1.000  1.000

09023571 9B   Squash, winter-babyfood            0.200000   1.000  1.000

95003590 O    Strawberry                         0.300000   1.000  1.000

95003591 O    Strawberry-babyfood                0.300000   1.000  1.000

95003600 O    Strawberry, juice                  0.300000   1.000  1.000

95003601 O    Strawberry, juice-babyfood         0.300000   1.000  1.000

20003640 20   Sunflower, seed                    0.020000   1.000  1.000

20003650 20   Sunflower, oil                     0.020000   1.000  1.000

20003651 20   Sunflower, oil-babyfood            0.020000   1.000  1.000

01033660 1CD  Sweet potato                       0.020000   1.000  1.000

01033661 1CD  Sweet potato-babyfood              0.020000   1.000  1.000

04023670 4B   Swiss chard                        4.000000   1.000  1.000

10003690 10   Tangerine                          0.400000   1.000  1.000

10003700 10   Tangerine, juice                   0.400000   0.600  1.000D34827

          Full comment: D348272

01033710 1CD  Tanier, corm                       0.020000   1.000  1.000

08003740 8    Tomatillo                          0.250000   1.000  1.000

08003750 8    Tomato                             0.250000   1.000  1.000

08003751 8    Tomato-babyfood                    0.250000   1.000  1.000

08003760 8    Tomato, paste                      0.800000   1.000  1.000Tol.

08003761 8    Tomato, paste-babyfood             0.800000   1.000  1.000Tol.

08003770 8    Tomato, puree                      0.250000   1.700  1.000

08003771 8    Tomato, puree-babyfood             0.250000   1.700  1.000

08003780 8    Tomato, dried                      0.250000  14.300  1.000

08003781 8    Tomato, dried-babyfood             0.250000  14.300  1.000

08003790 8    Tomato, juice                      0.250000   1.500  1.000

15003810 15   Triticale, flour                   0.020000   1.000  1.000

15003811 15   Triticale, flour-babyfood          0.020000   1.000  1.000

01033870 1CD  Turmeric                           0.020000   1.000  1.000

01013880 1AB  Turnip, roots                      0.050000   1.000  1.000

05023890 5B   Turnip, greens                     3.000000   1.000  1.000

14003910 14   Walnut                             0.020000   1.000  1.000

86010000 O    Water, direct, all sources         0.131770   1.000  1.000

86020000 O    Water, indirect, all sources       0.131770   1.000  1.000

09013990 9A   Watermelon                         0.200000   1.000  1.000

09014000 9A   Watermelon, juice                  0.200000   1.000  1.000

15004010 15   Wheat, grain                       0.020000   1.000  1.000

15004011 15   Wheat, grain-babyfood              0.020000   1.000  1.000

15004020 15   Wheat, flour                       0.020000   1.000  1.000

15004021 15   Wheat, flour-babyfood              0.020000   1.000  1.000

15004030 15   Wheat, germ                        0.020000   1.000  1.000

15004040 15   Wheat, bran                        0.020000   1.000  1.000

15004050 15   Wild rice                          0.020000   1.000  1.000

01034060 1CD  Yam, true                          0.020000   1.000  1.000

01034070 1CD  Yam bean                           0.020000   1.000  1.000

Attachment 2.	Input File for the Chronic Dietary Exposure Estimates.

U.S. Environmental Protection Agency                                 Ver. 2.00

DEEM-FCID Chronic analysis for THIAMETHOXAM                       1994-98 data

Residue file: C:\Documents and Settings\dmcneill\My Documents\Thiamethoxam\060109 2010 T+Water.R98

                                                           Adjust. #2 NOT used

Analysis Date 03-04-2010             Residue file dated: 03-04-2010/14:33:35/8

Reference dose (RfD) = 0.012 mg/kg bw/day

Comment:Acute and Chronic RfDs = aPAD and cPAD

------------------------------------------------------------------------ --------

Food Crop                                       Residue       Adj.Factors      Comment

EPA Code  Grp  Food Name                          (ppm)

                                                             #1         #2

-------- ---- -------------------------------   ---------- ------     ------   -------

14000030 14   Almond                             0.010000   1.000      1.000   D34927

  Full comment: D349272

14000031 14   Almond-babyfood                    0.010000   1.000      1.000

14000040 14   Almond, oil                        0.010000   1.000      1.000

14000041 14   Almond, oil-babyfood               0.010000   1.000      1.000

04010050 4A   Amaranth, leafy                    4.000000   1.000      1.000

11000070 11   Apple, fruit with peel             0.060000   1.000      1.000   D28170

  Full comment: D281702 & D265079

11000080 11   Apple, peeled fruit                0.060000   1.000      1.000

11000081 11   Apple, peeled fruit-babyfood       0.060000   1.000      1.000

11000090 11   Apple, dried                       0.060000   8.000      1.000

11000091 11   Apple, dried-babyfood              0.060000   8.000      1.000

11000100 11   Apple, juice                       0.060000   0.750      1.000

11000101 11   Apple, juice-babyfood              0.060000   0.750      1.000

11000110 11   Apple, sauce                       0.060000   1.000      1.000

11000111 11   Apple, sauce-babyfood              0.060000   1.000      1.000

12000120 12   Apricot                            0.210000   1.000      1.000   W. Cut

  Full comment: W. Cuthchin 12/10/03 DERs

12000121 12   Apricot-babyfood                   0.210000   1.000      1.000

12000130 12   Apricot, dried                     0.210000   6.000      1.000

12000140 12   Apricot, juice                     0.210000   1.000      1.000

12000141 12   Apricot, juice-babyfood            0.210000   1.000      1.000

95000160 O    Artichoke, globe                   0.190000   1.000      1.000   D28170

  Full comment: D281702/D325447

04010180 4A   Arugula                            4.000000   1.000      1.000

95000200 O    Avocado                            0.110000   1.000      1.000   D35744

  Full comment: D357449/D357450

09020210 9B   Balsam pear                        0.200000   1.000      1.000

15000250 15   Barley, pearled barley             0.086000   0.300      1.000   D28170

  Full comment: D281702/D325447

15000251 15   Barley, pearled barley-babyfood    0.086000   0.300      1.000

15000260 15   Barley, flour                      0.086000   0.100      1.000

15000261 15   Barley, flour-babyfood             0.086000   0.100      1.000

15000270 15   Barley, bran                       0.086000   0.300      1.000

06030300 6C   Bean, black, seed                  0.010000   1.000      1.000   S,. Ta

  Full comment: S,. Tayayin, 26 Nov 2002

06020310 6B   Bean, broad, succulent             0.010000   1.000      1.000

06030320 6C   Bean, broad, seed                  0.010000   1.000      1.000

06020330 6B   Bean, cowpea, succulent            0.010000   1.000      1.000

06030340 6C   Bean, cowpea, seed                 0.010000   1.000      1.000

06030350 6C   Bean,  great northern, seed        0.010000   1.000      1.000

06030360 6C   Bean, kidney, seed                 0.010000   1.000      1.000

06020370 6B   Bean, lima, succulent              0.010000   1.000      1.000

06030380 6C   Bean, lima, seed                   0.010000   1.000      1.000

06030390 6C   Bean, mung, seed                   0.010000   1.000      1.000

06030400 6C   Bean, navy, seed                   0.010000   1.000      1.000

06030410 6C   Bean, pink, seed                   0.010000   1.000      1.000

06030420 6C   Bean, pinto, seed                  0.010000   1.000      1.000

06010430 6A   Bean, snap, succulent              0.010000   1.000      1.000

06010431 6A   Bean, snap, succulent-babyfood     0.010000   1.000      1.000

21000440 M    Beef, meat                         0.020000   1.000      1.000

21000441 M    Beef, meat-babyfood                0.020000   1.000      1.000

21000450 M    Beef, meat, dried                  0.020000   1.920      1.000

21000460 M    Beef, meat byproducts              0.040000   1.000      1.000   Rec. T

  Full comment: Rec. Tol.

21000461 M    Beef, meat byproducts-babyfood     0.040000   1.000      1.000

21000480 M    Beef, kidney                       0.040000   1.000      1.000

21000490 M    Beef, liver                        0.040000   1.000      1.000

21000491 M    Beef, liver-babyfood               0.040000   1.000      1.000

01010500 1AB  Beet, garden, roots                0.050000   1.000      1.000

01010501 1AB  Beet, garden, roots-babyfood       0.050000   1.000      1.000

01010520 1A   Beet, sugar                        0.050000   1.000      1.000

01010521 1A   Beet, sugar-babyfood               0.050000   1.000      1.000

01010530 1A   Beet, sugar, molasses              0.050000   1.000      1.000

01010531 1A   Beet, sugar, molasses-babyfood     0.050000   1.000      1.000

13010550 13A  Blackberry                         0.120000   1.000      1.000   D28170

  Full comment: D281702

13010560 13A  Blackberry, juice                  0.120000   1.000      1.000

13010561 13A  Blackberry, juice-babyfood         0.120000   1.000      1.000

13020570 13B  Blueberry                          0.300000   1.000      1.000

13020571 13B  Blueberry-babyfood                 0.300000   1.000      1.000

13010580 13A  Boysenberry                        0.120000   1.000      1.000

14000590 14   Brazil nut                         0.010000   1.000      1.000

05010610 5A   Broccoli                           0.980000   1.000      1.000   D28170

  Full comment: D281702

05010611 5A   Broccoli-babyfood                  0.980000   1.000      1.000

05010620 5A   Broccoli, Chinese                  0.980000   1.000      1.000

05020630 5B   Broccoli raab                      0.820000   1.000      1.000

05010640 5A   Brussels sprouts                   0.980000   1.000      1.000

15000650 15   Buckwheat                          0.020000   1.000      1.000

15000660 15   Buckwheat, flour                   0.020000   1.000      1.000

01010670 1AB  Burdock                            0.050000   1.000      1.000

14000680 14   Butternut                          0.010000   1.000      1.000

05010690 5A   Cabbage                            0.980000   1.000      1.000

05020700 5B   Cabbage, Chinese, bok choy         0.820000   1.000      1.000   D28170

  Full comment: D281702

05010710 5A   Cabbage, Chinese, napa             0.980000   1.000      1.000

05010720 5A   Cabbage, Chinese, mustard          0.980000   1.000      1.000

95000740 O    Canistel                           0.400000   1.000      1.000

09010750 9A   Cantaloupe                         0.200000   1.000      1.000

04020760 4B   Cardoon                            4.000000   1.000      1.000

01010780 1AB  Carrot                             0.050000   1.000      1.000

01010781 1AB  Carrot-babyfood                    0.050000   1.000      1.000

01010790 1AB  Carrot, juice                      0.050000   1.000      1.000

09010800 9A   Casaba                             0.200000   1.000      1.000

14000810 14   Cashew                             0.010000   1.000      1.000

05010830 5A   Cauliflower                        0.980000   1.000      1.000

01010840 1AB  Celeriac                           0.050000   1.000      1.000

04020850 4B   Celery                             4.000000   1.000      1.000

04020851 4B   Celery-babyfood                    4.000000   1.000      1.000

04020860 4B   Celery, juice                      4.000000   1.000      1.000

04020870 4B   Celtuce                            4.000000   1.000      1.000

09020880 9B   Chayote, fruit                     0.200000   1.000      1.000

95000890 O    Cherimoya                          0.110000   1.000      1.000

12000900 12   Cherry                             0.210000   1.000      1.000

12000901 12   Cherry-babyfood                    0.210000   1.000      1.000

12000910 12   Cherry, juice                      0.210000   1.500      1.000

12000911 12   Cherry, juice-babyfood             0.210000   1.500      1.000

14000920 14   Chestnut                           0.010000   1.000      1.000

06030980 6C   Chickpea, seed                     0.010000   1.000      1.000

06030981 6C   Chickpea, seed-babyfood            0.010000   1.000      1.000

06030990 6C   Chickpea, flour                    0.010000   1.000      1.000

01011000 1AB  Chicory, roots                     0.050000   1.000      1.000

09021020 9B   Chinese waxgourd                   0.200000   1.000      1.000

04011040 4A   Chrysanthemum, garland             4.000000   1.000      1.000

10001060 10   Citrus citron                      0.100000   1.000      1.000

10001070 10   Citrus hybrids                     0.100000   1.000      1.000

10001080 10   Citrus, oil                        0.100000   0.600      1.000

95001150 O    Coffee, roasted bean               0.050000   1.000      1.000

95001160 O    Coffee, instant                    0.050000   1.000      1.000

05021170 5B   Collards                           0.820000   1.000      1.000

15001200 15   Corn, field, flour                 0.020000   1.000      1.000

15001201 15   Corn, field, flour-babyfood        0.020000   1.000      1.000

15001210 15   Corn, field, meal                  0.020000   1.000      1.000

15001211 15   Corn, field, meal-babyfood         0.020000   1.000      1.000

15001220 15   Corn, field, bran                  0.020000   1.000      1.000

15001230 15   Corn, field, starch                0.020000   1.000      1.000

15001231 15   Corn, field, starch-babyfood       0.020000   1.000      1.000

15001240 15   Corn, field, syrup                 0.020000   1.500      1.000

15001241 15   Corn, field, syrup-babyfood        0.020000   1.500      1.000

15001250 15   Corn, field, oil                   0.020000   1.000      1.000

15001251 15   Corn, field, oil-babyfood          0.020000   1.000      1.000

15001260 15   Corn, pop                          0.020000   1.000      1.000

15001270 15   Corn, sweet                        0.020000   1.000      1.000

15001271 15   Corn, sweet-babyfood               0.020000   1.000      1.000

95001280 O    Cottonseed, oil                    0.100000   1.000      1.000

95001281 O    Cottonseed, oil-babyfood           0.100000   1.000      1.000

11001290 11   Crabapple                          0.060000   1.000      1.000

95001300 O    Cranberry                          0.020000   1.000      1.000

95001301 O    Cranberry-babyfood                 0.020000   1.000      1.000

95001310 O    Cranberry, dried                   0.020000   1.000      1.000

95001320 O    Cranberry, juice                   0.020000   1.100      1.000

95001321 O    Cranberry, juice-babyfood          0.020000   1.100      1.000

04011330 4A   Cress, garden                      4.000000   1.000      1.000

04011340 4A   Cress, upland                      4.000000   1.000      1.000

09021350 9B   Cucumber                           0.200000   1.000      1.000

13021360 13B  Currant                            0.200000   1.000      1.000

13021370 13B  Currant, dried                     0.200000   1.000      1.000

04011380 4A   Dandelion, leaves                  4.000000   1.000      1.000

13011420 13A  Dewberry                           0.120000   1.000      1.000

08001480 8    Eggplant                           0.080000   1.000      1.000   D28170

  Full comment: D281702, tomato

13021490 13B  Elderberry                         0.200000   1.000      1.000

04011500 4A   Endive                             4.000000   1.000      1.000

04021520 4B   Fennel, Florence                   4.000000   1.000      1.000

14001550 14   Filbert                            0.010000   1.000      1.000

14001560 14   Filbert, oil                       0.010000   1.000      1.000

20001630 20   Flaxseed, oil                      0.020000   1.000      1.000   Tol.

01011680 1AB  Ginseng, dried                     0.050000   1.000      1.000

23001690 M    Goat, meat                         0.020000   1.000      1.000

23001700 M    Goat, meat byproducts              0.040000   1.000      1.000   Rec. T

  Full comment: Rec. Tol.

23001720 M    Goat, kidney                       0.040000   1.000      1.000

23001730 M    Goat, liver                        0.040000   1.000      1.000

13021740 13B  Gooseberry                         0.200000   1.000      1.000

95001750 O    Grape                              0.060000   1.000      1.000   D28170

  Full comment: D281702

95001760 O    Grape, juice                       0.060000   1.100      1.000

95001761 O    Grape, juice-babyfood              0.060000   1.100      1.000

95001770 O    Grape, leaves                      0.200000   1.000      1.000

95001780 O    Grape, raisin                      0.060000   2.300      1.000   D28170

  Full comment: D281702

95001790 O    Grape, wine and sherry             0.060000   1.000      1.000

10001800 10   Grapefruit                         0.070000   1.000      1.000

10001810 10   Grapefruit, juice                  0.070000   0.600      1.000

06031820 6C   Guar, seed                         0.010000   1.000      1.000

06031821 6C   Guar, seed-babyfood                0.010000   1.000      1.000

14001850 14   Hickory nut                        0.010000   1.000      1.000

09011870 9A   Honeydew melon                     0.200000   1.000      1.000

95001880 O    Hop                                0.100000   1.000      1.000

24001890 M    Horse, meat                        0.020000   1.000      1.000

01011900 1AB  Horseradish                        0.050000   1.000      1.000

13021910 13B  Huckleberry                        0.200000   1.000      1.000

05021940 5B   Kale                               0.820000   1.000      1.000

05011960 5A   Kohlrabi                           0.980000   1.000      1.000

10001990 10   Lemon                              0.090000   1.000      1.000

10002000 10   Lemon, juice                       0.090000   0.600      1.000

10002001 10   Lemon, juice-babyfood              0.090000   0.600      1.000

10002010 10   Lemon, peel                        0.090000   1.000      1.000

06032030 6C   Lentil, seed                       0.010000   1.000      1.000

04012040 4A   Lettuce, head                      4.000000   1.000      1.000

04012050 4A   Lettuce, leaf                      4.000000   1.000      1.000

10002060 10   Lime                               0.100000   1.000      1.000

10002070 10   Lime, juice                        0.100000   0.600      1.000

10002071 10   Lime, juice-babyfood               0.100000   0.600      1.000

13012080 13A  Loganberry                         0.120000   1.000      1.000

11002100 11   Loquat                             0.060000   1.000      1.000

14002130 14   Macadamia nut                      0.010000   1.000      1.000

95002150 O    Mango                              0.110000   1.000      1.000   D35744

  Full comment: D357449, avacado

95002151 O    Mango-babyfood                     0.110000   1.000      1.000

95002160 O    Mango, dried                       0.110000   1.000      1.000

95002170 O    Mango, juice                       0.110000   1.000      1.000

95002171 O    Mango, juice-babyfood              0.110000   1.000      1.000

28002210 M    Meat, game                         0.020000   1.000      1.000

27002220 D    Milk, fat                          0.020000   1.000      1.000

27002221 D    Milk, fat - baby food/infant for   0.020000   1.000      1.000

27012230 D    Milk, nonfat solids                0.020000   1.000      1.000

27012231 D    Milk, nonfat solids-baby food/in   0.020000   1.000      1.000

27022240 D    Milk, water                        0.020000   1.000      1.000

27022241 D    Milk, water-babyfood/infant form   0.020000   1.000      1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.020000   1.000      1.000

15002260 15   Millet, grain                      0.020000   1.000      1.000

05022290 5B   Mustard greens                     0.820000   1.000      1.000

12002300 12   Nectarine                          0.210000   1.000      1.000

15002310 15   Oat, bran                          0.020000   1.000      1.000

15002320 15   Oat, flour                         0.020000   1.000      1.000

15002321 15   Oat, flour-babyfood                0.020000   1.000      1.000

15002330 15   Oat, groats/rolled oats            0.020000   1.000      1.000

15002331 15   Oat, groats/rolled oats-babyfood   0.020000   1.000      1.000

08002340 8    Okra                               0.080000   1.000      1.000

03002370 3    Onion, dry bulb                    0.030000   1.000      1.000

03002371 3    Onion, dry bulb-babyfood           0.030000   1.000      1.000

03002380 3    Onion, dry bulb, dried             0.030000   9.000      1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.030000   9.000      1.000

10002400 10   Orange                             0.100000   1.000      1.000

10002410 10   Orange, juice                      0.100000   0.600      1.000

10002411 10   Orange, juice-babyfood             0.100000   0.600      1.000

10002420 10   Orange, peel                       0.100000   1.000      1.000

95002450 O    Papaya                             0.110000   1.000      1.000

95002451 O    Papaya-babyfood                    0.110000   1.000      1.000

95002460 O    Papaya, dried                      0.110000   1.800      1.000

95002470 O    Papaya, juice                      0.110000   1.500      1.000

04012480 4A   Parsley, leaves                    4.000000   1.000      1.000

01012500 1AB  Parsley, turnip rooted             0.050000   1.000      1.000

01012510 1AB  Parsnip                            0.050000   1.000      1.000

01012511 1AB  Parsnip-babyfood                   0.050000   1.000      1.000

06022550 6B   Pea, succulent                     0.010000   1.000      1.000

06022551 6B   Pea, succulent-babyfood            0.010000   1.000      1.000

06032560 6C   Pea, dry                           0.010000   1.000      1.000

06032561 6C   Pea, dry-babyfood                  0.010000   1.000      1.000

06012570 6A   Pea, edible podded, succulent      0.010000   1.000      1.000

06032580 6C   Pea, pigeon, seed                  0.010000   1.000      1.000

06022590 6B   Pea, pigeon, succulent             0.010000   1.000      1.000

12002600 12   Peach                              0.070000   1.000      1.000

12002601 12   Peach-babyfood                     0.070000   1.000      1.000

12002610 12   Peach, dried                       0.070000   7.000      1.000

12002611 12   Peach, dried-babyfood              0.070000   7.000      1.000

12002620 12   Peach, juice                       0.070000   1.000      1.000

12002621 12   Peach, juice-babyfood              0.070000   1.000      1.000

11002660 11   Pear                               0.060000   1.000      1.000

11002661 11   Pear-babyfood                      0.060000   1.000      1.000

11002670 11   Pear, dried                        0.060000   6.250      1.000

11002680 11   Pear, juice                        0.060000   0.750      1.000

11002681 11   Pear, juice-babyfood               0.060000   0.750      1.000

14002690 14   Pecan                              0.010000   1.000      1.000

08002700 8    Pepper, bell                       0.080000   1.000      1.000   D28170

  Full comment: D281702, pepper

08002701 8    Pepper, bell-babyfood              0.080000   1.000      1.000

08002710 8    Pepper, bell, dried                0.080000   1.000      1.000

08002711 8    Pepper, bell, dried-babyfood       0.080000   1.000      1.000

08002720 8    Pepper, nonbell                    0.080000   1.000      1.000

08002721 8    Pepper, nonbell-babyfood           0.080000   1.000      1.000

08002730 8    Pepper, nonbell, dried             0.080000   1.000      1.000

95002750 O    Peppermint                         1.500000   1.000      1.000

95002760 O    Peppermint, oil                    1.500000   0.050      1.000

14002820 14   Pistachio                          0.010000   1.000      1.000

12002850 12   Plum                               0.071000   1.000      1.000

12002851 12   Plum-babyfood                      0.071000   1.000      1.000

12002860 12   Plum, prune, fresh                 0.071000   1.000      1.000

12002861 12   Plum, prune, fresh-babyfood        0.071000   1.000      1.000

12002870 12   Plum, prune, dried                 0.071000   5.000      1.000

12002871 12   Plum, prune, dried-babyfood        0.071000   5.000      1.000

12002880 12   Plum, prune, juice                 0.071000   1.400      1.000

12002881 12   Plum, prune, juice-babyfood        0.071000   1.400      1.000

25002900 M    Pork, meat                         0.020000   1.000      1.000

25002901 M    Pork, meat-babyfood                0.020000   1.000      1.000

25002920 M    Pork, meat byproducts              0.020000   1.000      1.000

25002921 M    Pork, meat byproducts-babyfood     0.020000   1.000      1.000

25002940 M    Pork, kidney                       0.020000   1.000      1.000

25002950 M    Pork, liver                        0.020000   1.000      1.000

01032960 1C   Potato, chips                      0.250000   1.200      1.000

01032970 1C   Potato, dry (granules/ flakes)     0.250000   1.700      1.000

01032971 1C   Potato, dry (granules/ flakes)-b   0.250000   1.700      1.000

01032980 1C   Potato, flour                      0.250000   1.700      1.000

01032981 1C   Potato, flour-babyfood             0.250000   1.700      1.000

01032990 1C   Potato, tuber, w/peel              0.250000   1.000      1.000

01032991 1C   Potato, tuber, w/peel-babyfood     0.250000   1.000      1.000

01033000 1C   Potato, tuber, w/o peel            0.250000   1.000      1.000

01033001 1C   Potato, tuber, w/o peel-babyfood   0.250000   1.000      1.000

10003070 10   Pummelo                            0.100000   1.000      1.000

09023080 9B   Pumpkin                            0.200000   1.000      1.000

09023090 9B   Pumpkin, seed                      0.200000   1.000      1.000

11003100 11   Quince                             0.060000   1.000      1.000

29003120 M    Rabbit, meat                       0.020000   1.000      1.000

04013130 4A   Radicchio                          4.000000   1.000      1.000

01013140 1AB  Radish, roots                      0.050000   1.000      1.000

01013160 1AB  Radish, Oriental, roots            0.050000   1.000      1.000

05023180 5B   Rape greens                        0.820000   1.000      1.000

20003190 20   Rapeseed, oil                      0.020000   1.000      1.000

20003191 20   Rapeseed, oil-babyfood             0.020000   1.000      1.000

13013200 13A  Raspberry                          0.120000   1.000      1.000

13013201 13A  Raspberry-babyfood                 0.120000   1.000      1.000

13013210 13A  Raspberry, juice                   0.120000   1.000      1.000

13013211 13A  Raspberry, juice-babyfood          0.120000   1.000      1.000

04023220 4B   Rhubarb                            4.000000   1.000      1.000

15003230 15   Rice, white                        0.010000   1.000      1.000

15003231 15   Rice, white-babyfood               0.010000   1.000      1.000

15003240 15   Rice, brown                        0.010000   1.000      1.000

15003241 15   Rice, brown-babyfood               0.010000   1.000      1.000

15003250 15   Rice, flour                        0.010000   1.000      1.000

15003251 15   Rice, flour-babyfood               0.010000   1.000      1.000

15003260 15   Rice, bran                         0.010000   0.900      1.000

15003261 15   Rice, bran-babyfood                0.010000   0.900      1.000

01013270 1AB  Rutabaga                           0.050000   1.000      1.000

15003280 15   Rye, grain                         0.020000   1.000      1.000

15003290 15   Rye, flour                         0.020000   1.000      1.000

20003300 20   Safflower, oil                     0.020000   1.000      1.000

20003301 20   Safflower, oil-babyfood            0.020000   1.000      1.000

01013310 1AB  Salsify, roots                     0.050000   1.000      1.000

95003330 O    Sapote, Mamey                      0.400000   1.000      1.000

26003390 M    Sheep, meat                        0.020000   1.000      1.000

26003391 M    Sheep, meat-babyfood               0.020000   1.000      1.000

26003400 M    Sheep, meat byproducts             0.040000   1.000      1.000

26003420 M    Sheep, kidney                      0.040000   1.000      1.000

26003430 M    Sheep, liver                       0.040000   1.000      1.000

15003440 15   Sorghum, grain                     0.020000   1.000      1.000

15003450 15   Sorghum, syrup                     0.020000   1.000      1.000

06003470 6    Soybean, seed                      0.010000   1.000      1.000   D28170

  Full comment: D281702

06003480 6    Soybean, flour                     0.010000   1.000      1.000

06003481 6    Soybean, flour-babyfood            0.010000   1.000      1.000

06003490 6    Soybean, soy milk                  0.010000   1.000      1.000

06003491 6    Soybean, soy milk-babyfood or in   0.010000   1.000      1.000

06003500 6    Soybean, oil                       0.010000   1.000      1.000

06003501 6    Soybean, oil-babyfood              0.010000   1.000      1.000

95003520 O    Spearmint                          1.500000   1.000      1.000

95003530 O    Spearmint, oil                     1.500000   0.050      1.000   D28170

  Full comment: D281702

04013550 4A   Spinach                            4.000000   1.000      1.000

04013551 4A   Spinach-babyfood                   4.000000   1.000      1.000

09023560 9B   Squash, summer                     0.200000   1.000      1.000

09023561 9B   Squash, summer-babyfood            0.200000   1.000      1.000

09023570 9B   Squash, winter                     0.200000   1.000      1.000

09023571 9B   Squash, winter-babyfood            0.200000   1.000      1.000

95003590 O    Strawberry                         0.300000   1.000      1.000

95003591 O    Strawberry-babyfood                0.300000   1.000      1.000

95003600 O    Strawberry, juice                  0.300000   1.000      1.000

95003601 O    Strawberry, juice-babyfood         0.300000   1.000      1.000

20003640 20   Sunflower, seed                    0.020000   1.000      1.000

20003650 20   Sunflower, oil                     0.020000   1.000      1.000

20003651 20   Sunflower, oil-babyfood            0.020000   1.000      1.000

01033660 1CD  Sweet potato                       0.020000   1.000      1.000

01033661 1CD  Sweet potato-babyfood              0.020000   1.000      1.000

04023670 4B   Swiss chard                        4.000000   1.000      1.000

10003690 10   Tangerine                          0.100000   1.000      1.000

10003700 10   Tangerine, juice                   0.100000   0.600      1.000

01033710 1CD  Tanier, corm                       0.020000   1.000      1.000

08003740 8    Tomatillo                          0.080000   1.000      1.000

08003750 8    Tomato                             0.080000   1.000      1.000

08003751 8    Tomato-babyfood                    0.080000   1.000      1.000

08003760 8    Tomato, paste                      0.080000   3.800      1.000   D26507

  Full comment: D265079

08003761 8    Tomato, paste-babyfood             0.080000   3.800      1.000

08003770 8    Tomato, puree                      0.080000   1.700      1.000   D26507

  Full comment: D265079

08003771 8    Tomato, puree-babyfood             0.080000   1.700      1.000

08003780 8    Tomato, dried                      0.080000  14.300      1.000

08003781 8    Tomato, dried-babyfood             0.080000  14.300      1.000

08003790 8    Tomato, juice                      0.080000   1.500      1.000

15003810 15   Triticale, flour                   0.020000   1.000      1.000

15003811 15   Triticale, flour-babyfood          0.020000   1.000      1.000

01033870 1CD  Turmeric                           0.250000   1.000      1.000

01013880 1AB  Turnip, roots                      0.050000   1.000      1.000

05023890 5B   Turnip, greens                     0.820000   1.000      1.000

14003910 14   Walnut                             0.010000   1.000      1.000

86010000 O    Water, direct, all sources         0.011310   1.000      1.000

86020000 O    Water, indirect, all sources       0.011310   1.000      1.000

09013990 9A   Watermelon                         0.200000   1.000      1.000

09014000 9A   Watermelon, juice                  0.200000   1.000      1.000

15004010 15   Wheat, grain                       0.020000   1.000      1.000

15004011 15   Wheat, grain-babyfood              0.020000   1.000      1.000

15004020 15   Wheat, flour                       0.020000   1.000      1.000

15004021 15   Wheat, flour-babyfood              0.020000   1.000      1.000

15004030 15   Wheat, germ                        0.020000   1.000      1.000

15004040 15   Wheat, bran                        0.020000   1.000      1.000

15004050 15   Wild rice                          0.020000   1.000      1.000

01034060 1CD  Yam, true                          0.250000   1.000      1.000

01034070 1CD  Yam bean                           0.250000   1.000      1.000

Attachment 3.  Summary of the acute dietary exposure analysis for thiamethoxam.

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for THIAMETHOXAM                        (1994-98 data)

Residue file:<PHONE_NUMBER> Acute T+Water.R98       Adjustment factor #2 NOT used.

Analysis Date: 03-04-2010/14:42:21    Residue file dated: 03-04-2010/14:31:37/8

Daily totals for food and foodform consumption used.

Run Comment: "Acute and Chronic RfDs = aPAD and cPAD"

======================================================================== =======

Summary calculations (per capita):

                    95th Percentile      99th Percentile      99.9th Percentile

                   Exposure   % aRfD    Exposure   % aRfD    Exposure   % aRfD

                  ---------- --------  ---------- --------  ---------- --------

U.S. Population:

                    0.018088     5.17    0.029783     8.51    0.058399    16.69

All infants:

                    0.033163     9.48    0.053495    15.28    0.087403    24.97

Children 1-2 yrs:

                    0.032980     9.42    0.056583    16.17    0.108262    30.93

Children 3-5 yrs:

                    0.026607     7.60    0.046287    13.22    0.078998    22.57

Children 6-12 yrs:

                    0.018827     5.38    0.034687     9.91    0.070883    20.25

Youth 13-19 yrs:

                    0.014308     4.09    0.022198     6.34    0.038728    11.07

Adults 20-49 yrs:

                    0.016273     4.65    0.025229     7.21    0.042138    12.04

Adults 50+ yrs:

                    0.016610     4.75    0.025537     7.30    0.040483    11.57

Females 13-49 yrs:

                    0.016146     4.61    0.025614     7.32    0.046369    13.25

Attachment 4.  Summary of the chronic dietary exposure analysis for thiamethoxam.

U.S. Environmental Protection Agency                                 Ver. 2.00

DEEM-FCID Chronic analysis for THIAMETHOXAM                     (1994-98 data)

Residue file name: C:\Documents and Settings\dmcneill\My Documents\Thiamethoxam\060109 2010 T+Water.R98

                                                 Adjustment factor #2 NOT used.

Analysis Date 03-04-2010/14:34:29     Residue file dated: 03-04-2010/14:33:35/8

Reference dose (RfD, Chronic) = .012 mg/kg bw/day

COMMENT 1: Acute and Chronic RfDs = aPAD and cPAD

======================================================================== =======

                    Total exposure by population subgroup

------------------------------------------------------------------------ -------

                                                    Total Exposure

                                         -----------------------------------

          Population                         mg/kg             Percent of

           Subgroup                       body wt/day             Rfd

--------------------------------------   -------------       ---------------

U.S. Population (total)                     0.002795                23.3%

U.S. Population (spring season)             0.002864                23.9%

U.S. Population (summer season)             0.002784                23.2%

U.S. Population (autumn season)             0.002755                23.0%

U.S. Population (winter season)             0.002778                23.1%

Northeast region                            0.002900                24.2%

Midwest region                              0.002814                23.4%

Southern region                             0.002515                21.0%

Western region                              0.003123                26.0%

Hispanics                                   0.002879                24.0%

Non-hispanic whites                         0.002797                23.3%

Non-hispanic blacks                         0.002415                20.1%

Non-hisp/non-white/non-black                0.003638                30.3%

All infants (< 1 year)                      0.003002                25.0%

Nursing infants                             0.001314                10.9%

Non-nursing infants                         0.003643                30.4%

Children 1-6  yrs                           0.004543                37.9%

Children 7-12 yrs                           0.003090                25.7%

h

ਁ䠃愀϶ר܀

*

+

,

%P

s

˜

™

½

Ù

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

퀀ࠂ䀇

摧圖¿

&

&

”ÿ™	p

h	.

@

&

@

o

¿

O

Ÿ

ï

gd

h

 20.4%

Females 13+ (nursing)                       0.003097                25.8%

Males 13-19 yrs                             0.002370                19.7%

Males 20+ yrs                               0.002469                20.6%

Seniors 55+                                 0.002601                21.7%

Children 1-2 yrs                            0.005065                42.2%

Children 3-5 yrs                            0.004446                37.1%

Children 6-12 yrs                           0.003196                26.6%

Youth 13-19 yrs                             0.002308                19.2%

Adults 20-49 yrs                            0.002567                21.4%

Adults 50+ yrs                              0.002625                21.9%

Females 13-49 yrs                           0.002595                21.6%

------------------------------------------------------------------------ -------

Thiamethoxam (060109) 	        Dietary Exposure and Risk Assessment	          	   DP Numbers D373595/D375247

 PAGE

Page   PAGE  25  of   NUMPAGES  26

DRAFT – Confidential, Internal, and Deliberative Material

[Chemical Name]	Dietary Exposure and Risk Assessment	DP Number: [xxxxxxx]

PC Code:  [xxxxxx]