G, J, K See 830.7860 830.7860 63 8 Water Solubility, generator column method A, B, C, E, F,

G, J, K 00145872 50 830.7950 63 9 Vapor Pressure A, B, C, E, F,

G, J, K 00145782 ECOLOGICAL EFFECTS 850.2100 71 1( a) Avian Oral LD50 Quail/ Duck A, B, C, E, F,

G, J, K 00131633, 00131634 850.2200 71 2( a) Avian Dietary LC50 Quail A, B, C, E, F,

G, J, K 00131635, 0013552, 00133553 850.2200 71 2( b) Avian Dietary LC50 Duck A, B, C, E, F,

G, J, K 00131636, 00131551 850.2300 71 4( a) Avian Reproduction Quail A, B, C, E, F,

G, J, K 45119714, 43831401 850.2300 71 4( b) Avian Reproduction Duck A, B, C, E, F,

G, J, K 43831402 850.1075 72 1( a) Freshwater Fish LC50 Bluegill ( warm water) A, B, C, E, F,

G, J, K 00133549 850.1075 72 1( b) Freshwater Fish LC50 Channel Catfish A, B, C, E, F,

G, J, K 00131631 850.1075 72 1( c) Freshwater Fish LC50 Rainbow trout ( cold water) A, B, C, E, F,

G, J, K 45119713 850.1010 72 2( a) Freshwater Invertebrate LC50 Daphnia magna A, B, C, E, F,

G, J, K 00131632, 01133550 850.1045 72 3( a) Estuarine/ Marine Fish LC50 A, B, C, E, F,

G, J, K 41315801 850.1025 72 3( b) Estuarine/ Marine Mollusk EC50 A, B, C, E, F,

G, J, K 41315802, 45119709, 45119710 850.1035 72 3( c) Estuarine/ Marine Shrimp EC50 A, B, C, E, F,

G, J, K 41315803 51 850.1400 72 4( a) Fish Early Life Stage Rainbow Trout ( freshwater) A, B, C, E, F,

G, J, K 41315804 850.1400 72 4( a) Fish Early Life Stage Fathead Minnow ( estuarine/ marine) A, B, C, E, F,

G, J, K 45119711 850.1350 72 4( b) Aquatic Invertebrate Life Cycle ( freshwater) A, B, C, E, F,

G, J, K 41315805 850.1500 72 5 Freshwater Fish Full Life Cycle A, B, C, E, F,

G, J, K 45119712 850.171 72 6 Aquatic Organism Accumulation A, B, C, E, F,

G, J, K 00147120 850.4225 122 1 Seed Germ./ Seedling Emergence ( Tier 2) A, B, C, E, F,

G, J, K 40003711, Data Gap 850.4400 122 2 Aquatic Plant Growth ( Tier 2) A, B, C, E, F,

G, J, K 43889102, 40811802 850.4250 123 1 Vegetative Vigor ( Tier 2) A, B, C, E, F,

G, J, K 43889101, 40811801, 40811802Data Gap 850.4450 124 2 Aquatic Field A, B, C, E, F,

G, J, K 40811802, 00131628, 00131629, 00131637, 00133554, 00147114 850.3020 141 1 Honey Bee Acute Contact LD50 A, B, C, E, F,

G, J, K 00131637 TOXICOLOGY 870.1100 81 1 Acute Oral Toxicity Rat A, B, C, E, F,

G, J, K 41551002, 93048016 870.1200 81 2 Acute Dermal Toxicity

Rabbit/ Rat A, B, C, E, F,

G, J, K 41551003, 93048017 870.1300 81 3 Acute Inhalation Toxicity Rat A, B, C, E, F,

G, J, K 00132032, 93048018 52 870.2400 81 4 Primary Eye Irritation Rabbit A, B, C, E, F,

G, J, K 41551001, 93048019, Accession# 252004 870.2500 81 5 Primary Skin Irritation A, B, C, E, F,

G, J, K 41551004, 93048020 870.2600 81 6 Dermal Sensitization A, B, C, E, F,

G, J, K 00131607, 93048021 870.3100 82 1( a) 90 Day Feeding  Rodent A, B, C, E, F,

G, J, K 42774401 870.3200 82 2 21 Day Dermal  Rabbit/ Rat A, B, C, E, F,

G, J, K 00131609, 93048022 870.3700a 83 3( a) Developmental Toxicity ( Teratogenicity)  rat A, B, C, E, F,

G, J, K 00131611, 93048023 870.3700b 83 3( b) Developmental Toxicity ( Teratogenicity)  rabbit A, B, C, E, F,

G, J, K 00131613, 93048024 870.3800 83 4 2 Generation Reproduction  Rat A, B, C, E, F,

G, J, K 41039505 870.4100a 83 1 Chronic Toxicity  Rat A, B, C, E, F,

G, J, K N/ A; see 870.4300 870.4100b 83 1 Chronic Toxicity  Dog A, B, C, E, F,

G, J, K 41039502 870.4200a 83 2 Carcinogenicity  Rat A, B, C, E, F,

G, J, K N/ A; see 870.4300 870.4200b 83 2 Carcinogenicity  Mouse A, B, C, E, F,

G, J, K 41038505, 42774401 870.4300 83 5 Combined Chronic/ Carcinogenicity A, B, C, E, F,

G, J, K 41039503 53 870.5100 84 2 Bacterial Reverse Mutation ( Ames Assay) A, B, C, E, F,

G, J, K 00131615, 93048025 870.5300 84 2 In vitro Mammalian Cell Gene Mutation A, B, C, E, F,

G, J, K 00151641, 93048028 870.5375 84 2 In vitro Mammalian Chromosome Aberration ( CHO) A, B, C, E, F,

G, J, K 00151640, 93048026 870.5450 84 2 Rodent Dominant Lethal A, B, C, E, F,

G, J, K 00151638 870.5500 84 2 Unscheduled DNA Synthesis A, B, C, E, F,

G, J, K 00151639, 93048027 870.7485 85 1 Metabolism and Pharmacokinetics  Rat A, B, C, E, F,

G, J, K 43861501 870.7600 85 3 Dermal Absorption   Rat N/ A N/ A ENVIRONMENTAL FATE 835.2120 161 1 Hydrolysis A, B, C, E, F,

G, J, K 00132359, 00131617, 00131639, 00133557 835.2240 161 2 Photodegradation  Water A, B, C, E, F,

G, J, K 00131617 835.4100 162 1 Aerobic Soil Metabolism A, B, C, E, F,

G, J, K 00131619, 41002301, 00131618, 00133557, 45119701 835.4200 162 2 Anaerobic Soil Metabolism A, B, C, E, F,

G, J, K 00131619, 41023201, 45119701 835.4400 162 3 Anaerobic Aquatic Metabolism A, B, C, E, F,

G, J, K 40003712 835.4300 162 4 Aerobic Aquatic Metabolism A, B, C, E, F,

G, J, K 41002301, 45119702 54 835.1240 163 1 Leaching/ Adsorption/ Desorption A, B, C, E, F,

G, J, K 00131620, 00131620, 00133557, 43423703, 45119705 835.6100 164 1 Terrestrial Field Dissipation A, B, C, E, F,

G, J, K 00131621, 42192101,42192102, 45119705, 45119706, 00131622,

00131623, 00131624, 0013357, 00147119 835.6200 164 2 Aquatic Field Dissipation A, B, C, E, F,

G, J, K 41891501, 45119707, 45119708 835.6500 164 5 Long Term Soil Dissipation A, B, C, E, F,

G, J, K 45119706 N/ A 165 4 Accumulation in Fish A, B, C, E, F,

G, J, K 00147120 N/ A 165 5 Accumulation   Aquatic Nontarget A, B, C, E, F,

G, J, K 45119722 835.7100 166 1 Ground Water Monitoring A, B, C, E, F,

G, J, K 44746701, 44746702, 44746703, 44865101, 44865102, 44975001,

45035201, 45139101, 45139102, 45212601, 45212602, 45335301,

45335302, 45410001, 45410002, 45498201, 45212602, 45335301,

45335302, 45410001, 45410002, 45498201, 45498202, 45663801,

45663802, 45677401 840.1100 201 1 Spray Droplet Size Spectrum A, B, C, E, F,

G, J, K 41516301 840.2100 202 1 Spray Drift Field Deposition A, B, C, E, F,

G, J, K 41516301 55 RESIDUE CHEMISTRY 860.1300 171 4( a) Nature of Residue in Plants A, B, C, E, F,

G, J, K 45119715 860.1300 171 4( b) Nature of Residue in Livestock A, B, C, E, F,

G, J, K 45119716 860.1340 171 4( c) Residue Analytical Method

plant A, B, C, E, F,

G, J, K 45119718 860.1340 171 4( d) Residue Analytical Method

livestock A, B, C, E, F,

G, J, K 45119718 860.1340 171 4( d) Residue Analytical Method

Water/ fish A, B, C, E, F,

G, J, K Data Gap 860.1360 171 4( m) Multiple Residue Methods N/ A N/ A 860.1380 171 4( e) Storage Stability Data A, B, C, E, F,

G, J, K 45119719, Data Gap 860.1400 171 4( h) Fish, water, & irrigated crops A, B, C, G, J, K 45119709, 45119722, 4519707, Data Gap 860.1480 171 4( j) Milk, Meat, Poultry, & Eggs A, B, C, E, F,

G, J, K 45119721 860.1500 171 4( k) Cropfield Residue ( Grass,

Forage, & Hay) A, B, C, E, F,

G, J, K 45119720, Data Gap 860.1520 171 4( l) Processed Food/ Feed N/ A N/ A 56 860.1650 171 13 Submittal of Analytical Reference Standards A, B, C, E, F,

G, J, K Submitted to EPA National Pesticide Standards Repository 860.1850 165 1 Confined rotational crops A, B, C, E, F,

G, J, K 45119717 860.1900 165 2 Field rotational crops A, B, C, E, F,

G, J, K 45119717 HED concludes that there are no outstanding residue chemistry data requirements that would preclude the reassessment of tolerance levels for reregistration purposes, provided that:

  the registrant submits an acceptable fish metabolism study,

  the registrant submits adequate corn or grass storage stability information,

  the registrant specifies the identity and quantity of spray additives used in all of the grass field trials,

  the analytical enforcement method is determined to be adequate, and   labels are revised to prohibit use of treated waters on irrigated crops for 120 days after treatment or residue data is provided for irrigated crops.

A few data gaps were identified for imazapyr in a few different use areas that include:

  applying sprayers to aquatic sites via helicopters ( PHED data for fixed wind aerial spray applications were used as a reasonable surrogate); and   mixing/ loading/ applying liquids to trees via injection equipment ( no surrogate data are available at this time).

For all agricultural postapplication exposure scenarios, data gaps exist such as a lack of imazapyr specific postapplication studies. 57 Appendix C. Technical Support Documents Additional documentation in support of this RED is maintained in the OPP Regulatory Public Docket ( 7502P), Environmental Protection Agency, Rm. S 4400, One Potomac Yard ( South Building), 2777 S. Crystal Drive, Arlington, VA. It is open Monday through Friday, excluding legal holidays, from 8: 30 a. m. to 4: 00 p. m.

All documents, in hard copy form, may be viewed in the OPP docket room or downloaded or viewed via the Internet at the following site:

http:// docket. epa. gov/ edkpub/ index. jsp These documents include:

1. Federal Register Notice: Imazapyr Reregistration Eligibility Decision; Notice of Availability 2. Reader's Guide to the Imazapyr EDOCKET OPP 2005 495 3. Imazapyr Reregistration Eligibility Decision 4. Imazapyr: Chronic Dietary Exposure Assessment for the Section 3 Registration Action on Grasses and Aquatic Sites, PC Code: 128821, DP Barcode D288806 ( March 26, 2003).

5. Imazapyr: Revised Health Effects Division ( HED) Chapter of the Reregistration Eligibility Document ( RED), PC Code: 128821, CAS Reg 81334 34 1, Case # 3078, DP Barcode D324106 ( December 8, 2005).

6. Imazapyr: Occupational and Residential Exposure Assessment for the Reregistration Eligibility Decision Document, PC Code: 128821, DP Barcode D320582, ( August 31, 2005).

7. Response to Error Only Comments on the EFED Ecological Risk Assessment Supporting the RED for the Herbicide, Imazapyr, PC Code: 128821, DP Barcodes: 324101, 324103, ( December 9, 2005).

8. Imazapyr: Summary of Product Chemistry Data for Reregistration Eligibility Decision ( RED) Document, PC Code: 128821, DP Barcode: D320579 ( August 29, 2005).

9. Level I Screening Ecological Risk Assessment for the Reregistration of Imazapyr, CAS Number: 81334 34 1. 58 Appendix D. CITATIONS CONSIDERED TO BE PART OF THE DATA BASE SUPPORTING THE REREGISTRATION DECISION ( BIBLIOGRAPHY)

GUIDE TO APPENDIX D 1. CONTENTS OF BIBLIOGRAPHY. This bibliography contains citations of all studies considered relevant by EPA in arriving at the positions and conclusions stated elsewhere in the Reregistration Eligibility Document. Primary sources for studies in this bibliography have been the body of data submitted to EPA and its predecessor agencies in support of past regulatory decisions. Selections from other sources including the published literature, in those instances where they have been considered, are included.

2. UNITS OF ENTRY. The unit of entry in this bibliography is called a " study." In the case of published materials, this corresponds closely to an article. In the case of unpublished materials submitted to the Agency, the Agency has sought to identify documents at a level parallel to the published article from within the typically larger volumes in which they were submitted. The resulting " studies" generally have a distinct title ( or at least a single subject), can stand alone for purposes of review and can be described with a conventional bibliographic citation. The Agency has also attempted to unite basic documents and commentaries upon them, treating them as a single study.

3. IDENTIFICATION OF ENTRIES. The entries in this bibliography are sorted numerically by Master Record Identifier, or " MRID" number. This number is unique to the citation, and should be used whenever a specific reference is required. It is not related to the six digit " Accession Number" which has been used to identify volumes of submitted studies ( see paragraph 4( d)( 4) below for further explanation). In a few cases, entries added to the bibliography late in the review may be preceded by a nine character temporary identifier. These entries are listed after all MRID entries. This temporary identifying number is also to be used whenever specific reference is needed.

4. FORM OF ENTRY. In addition to the Master Record Identifier ( MRID), each entry consists of a citation containing standard elements followed, in the case of material submitted to EPA, by a description of the earliest known submission. Bibliographic conventions used reflect the standard of the American National Standards Institute ( ANSI), expanded to provide for certain special needs.

a Author. Whenever the author could confidently be identified, the Agency has chosen to show a personal author. When no individual was identified, the Agency has shown an identifiable laboratory or testing facility as the author. When no author or laboratory could be identified, the Agency has shown the first submitter as the author.

b. Document date. The date of the study is taken directly from the document. When the date is followed by a question mark, the bibliographer has deduced the date from the evidence contained in the document. When the date appears as ( 1999), the Agency was unable to determine or estimate the date of the document. 59 c. Title. In some cases, it has been necessary for the Agency bibliographers to create or enhance a document title. Any such editorial insertions are contained between square brackets.

d. Trailing parentheses. For studies submitted to the Agency in the past, the trailing parentheses include ( in addition to any self explanatory text) the following elements describing the earliest known submission:

( 1) Submission date. The date of the earliest known submission appears immediately following the word " received."

( 2) Administrative number. The next element immediately following the word " under" is the registration number, experimental use permit number, petition number, or other administrative number associated with the earliest known submission.

( 3) Submitter. The third element is the submitter. When authorship is defaulted to the submitter, this element is omitted.

( 4) Volume Identification ( Accession Numbers). The final element in the trailing parentheses identifies the EPA accession number of the volume in which the original submission of the study appears. The six digit accession number follows the symbol " CDL," which stands for " Company Data Library." This accession number is in turn followed by an alphabetic suffix which shows the relative position of the study within the volume. 60 Bibliography MRID Citation Reference 131607 Ledoux, T. ( 1983) Evaluation of the Sensitization Potential of AC 243,997 in Guinea Pigs: T. P. S. Study No. 186A 201

231 83; Spon sor Study No. 981 83 129. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxicology Pathology Services, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 251503 A)

131609 Larson, D.; Kelly, W. ( 1983) Twenty one Day Dermal Toxicity Study with AC 243,997 in Rabbits: T. P. S. Study No.

186B 301 230 83; Sponsor I. D. No. 981 83 127. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxicology Pathology Services, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 251503 C)

131611 Salamon, C.; Enloe, P.; Mayhew, D.; et al. ( 1983) Teratology Study in Albino Rats with AC 243,997: Toxigenics' Study 450 1222. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxigenics, Inc., submitted by American Cyanamid Co., Prince ton, NJ; CDL: 251504 A)

131612 Salamon, C.; Enloe, P.; Taylor, G.; et al. ( 1983) Teratology Pilot Study in Albino Rats with AC 243,997: Toxigenics'

Study 450 1221. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxigenics, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 251504 B)

131613 Salamon, C.; Enloe, P.; Becker, S.; et al. ( 1983) Teratology Study in Albino Rabbits with AC 243,997: Toxigenics' Study 450 1224. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxigenics, Inc., submitted by American Cyanamid Co., Prince ton, NJ; CDL: 251504 C)

131614 Salamon, C.; Enloe, P.; Becker, S.; et al. ( 1983) Teratology Pilot Study in Albino Rabbits with AC 243,997: Toxigenics'

Study 450 1223. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Toxigenics, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 251504 D)

131615 Allen, J.; Fine, B.; Johnson, E.; et al. ( 1983) Bacterial/ Microsome Reverse Mutation ( Ames) Test on CL 243,997: Project No. 0493; GTOX 5: 1 23. Final rept. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251504 E)

131616 Mallipudi, N.; Stout, S.; Stanley Millner, P.; et al. ( 1983) Herbi cide AC 243,997: The Absorption, Excretion, Tissue Residues and Metabolism of Carboxyl Carbon 14 Labeled AC 243,997 ... in the Rat: Report No. PD M Volume 20 13: 1

83. ( Unpublished study re ceived Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ;

CDL: 251504 F) 61 131617 Mallipudi, M.; Knoll, B.; Bullock, M.; et al. ( 1983) Arsenal Herbi cide ( AC 243,997): Photolysis of Carbon 14 Labeled AC 243,997 ? Nicotinic Acid, 2( 4 Isopropyl 4 methyl 5 oxo 2 imidazolin 2 yl)| in Aqueous Media: Report No. PD M Volume 20 20. ( Unpub lished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co.,

Princeton, NJ; CDL: 251505 B)

131618 Mallipudi, M.; DaCunha, A.; Stanley Millner, P.; et al. ( 1983) Arsenal Herbicide ( AC 243,997): Aerobic Soil Metabolism of Car boxyl Carbon 14 Labeled AC 243,997 ... in Sandy Loam Soil: Report No. PDM Volume 20 17. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Prince ton, NJ; CDL: 251505 C)

131619 Mallipudi, N.; Knoll, B.; Stout, S.; et al. ( 1983) Arsenal Herbi cide ( AC 243,997): Anaerobic Soil Metabolism of Carboxyl Carbon 14 Labeled AC 243,997 ... in Sandy Loam Soil: Report No. PD M Volume 20 15. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251505 D)

131620 Mallipudi, M.; Hewel, D.; Knoll, B.; et al. ( 1983) Arsenal Herbi cide ( AC 243,997): Adsorption and Desorption Coefficients for Soils: Report No. PD M Volume 20 18. ( Unpublished study re ceived Oct 6, 1983 under 241 273;

submitted by American Cyanamid Co., Princeton, NJ; CDL: 251505 E)

131621 Mallipudi, M.; Knoll, B.; Stanley Miller, P. ( 1983) Arsenal Herbi cide ( AC 243,997): Field Dissipation of Carboxyl Carbon 14 La beled AC 243,997 ...: Report No. PD M Volume 20 19. ( Unpub lished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251505 F)

131622 Picard, G.; Tafuro, A.; Elenewski, C.; et al. ( 1982) CL 243,997: Residues of CL 243,997 in Soil ( Post; NY, 1981) ( C

2026): Report No. C 2030. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251505 G)

131623 Elenewski, C.; Tafuro, A.; Cornelius, A. ( 1983) CL 243,997: Resi dues of CL 243,997 in Soil ( Post; MO, 1981) ( C

2026): Report No. C 2029.1. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251505 H)

131624 Picard, G.; Orwick, P. ( 1981) CL 243,997: Residues of CL 243,997 in Soil ( PRE; NJ 1980) ( C 1819): Report No. C

1880. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ;

CDL: 251505 I)

131625 Picard, G.; Orwick, P.; Robert, W. ( 1981) CL 243,997: Residues of CL 243,997 in Soil ( PRE; MI, 1980)( C 1819): Report No. C 1878. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton,

NJ; CDL: 251505 J) 62 131626 Picard, G. ( 1981) CL 243,997: Validation of GC Method M 1131 for the Determination of CL 243,997 Residues in Soil:

Report No. C 1819. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co.,

Princeton, NJ; CDL: 251505 K)

131627 Picard, G.; Elenewski, C. ( 1982) CL 243,997: Validation of GC Method M 1205 for the Determination of CL 243,997 Residues in Soil: Report No. C 2026. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Prince ton, NJ; CDL: 251505 L)

131628 American Cyanamid Co. ( 1983) Summary: Fish and Wildlife Data: AC 243,997. ( Compilation; unpublished study received Oct 6, 1983 under 241 273; CDL: 251506 A)

131629 Kintner, D.; Forbis, A. ( 1983) Acute Toxicity of AC 243,997 to Rainbow Trout ( Salmo gairdneri): Static Bioassay Report # 30095. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Analytical Bio Chemistry Laboratories,

Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 251506 B)

131630 Kintner, D.; Forbis, A. ( 1983) Acute Toxicity of AC 243,997 to Bluegill Sunfish ( Lepomis macrochirus): Static Bioassay Report # 30096. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Analytical Bio Chemistry Laboratories, Inc., submit ted by American Cyanamid Co., Princeton, NJ; CDL: 251506 C)

131631 Forbis, A.; Kintner, D. ( 1983) Acute Toxicity of AC 243,997 to Channel Catfish ( Ictalurus punctatus): Static Bioassay Report 30097. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Analytical Bio Chemistry Laboratories, Inc., submit ted by American Cyanamid Co., Princeton, NJ; CDL: 251506 D)

131632 Kintner, D.; Forbis, A. ( 1983) Acute Toxicity of AC 243,997 to Daphnia magna: Static Acute Bioassay Report # 30098.

( Unpub lished study received Oct 6, 1983 under 241 273; prepared by Analytical Bio Chemistry Laboratories, Inc.,

submitted by Ameri can Cyanamid Co., Princeton, NJ; CDL: 251506 E)

131633 Fletcher, D. ( 1983) Report to ...: Acute Oral Toxicity Study with AC 243,997 in Bobwhite Quail: BLAL No. 83 QD 20;

AC No. 981 83 116. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyana mid Co., Princeton, NJ; CDL: 251506 F)

131634 Fletcher, D. ( 1983) Report to ...: Acute Oral Toxicity Study with AC 243,997 in Mallard Ducks: BLAL No. 83 DD 16;

AC No. 981 83 115. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyana mid Co., Princeton, NJ; CDL: 251506 G) 63 131635 Fletcher, D. ( 1983) Report to ...: 8 Day Dietary LC50 Study with AC 243,997 in Bobwhite Quail: BLAL No. 83 QC 23;

AC No. 981 83 114. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyanamid Co., Princeton, NJ; CDL: 251506 H)

131636 Fletcher, D. ( 1983) Report to ...: 8 Day Dietary LC50 Study with AC 243,997 in Mallard Ducklings: BLAL No. 83 DC 23; AC No. 981 83 113. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyana mid Co., Princeton, NJ; CDL: 251506 I)

131637 Atkins, E. ( 1983) Letter sent to T. Peoples dated Apr 16, 1983 ? Honeybee toxicity study with AC 243,997|. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Univ. of Cali fornia Riverside, Dept. of Entomology, submitted by American Cyanamid Co., Princeton, NJ; CDL: 251506 J)

131638 Atlas, R. ( 1983) Assessment of the Effects of the Herbicide AC 243,997 on Soil Microorganisms. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Univ. of Louisville, Dept. of Biology, submitted by American Cyanamid Co., Princeton, NJ; CDL: 251506 K)

131639 Reichert, B.; Stanley Millner, P. ( 1983) Herbicide AC 243,997: De termination of the Partition Coefficient in n

Octanol/ Water: Report No. PD M Volume 20 10. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251506 L)

132028 American Cyanamid Co. ( 1983) Product Chemistry: ( AC 243,997 and Arsenal Herbicide). ( Compilation; unpublished study received Oct 6, 1983 under 241 273; CDL: 251500 A)

132029 American Cyanamid Co. ( 19??) Summary: Toxicology Data: ( AC 243,997). ( Unpublished study received Oct 6, 1983 under 241 273; CDL: 251502 A)

132030 Fischer, J. ( 1983) Toxicity Data Report: ( 2( 4 Isopropyl 4 methyl 5 oxo 2 imidazolin 2 yl) Nicotinic Acid: Rats and Rabbits): Report No. A83 24. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co., Princeton, NJ; CDL: 251502 B)

132031 Fischer, J. ( 1983) Toxicity Data Report: ( Isopropylamine Salt of 2 ( 4 isopropyl 4 methyl 5 oxo 2 imadazolin 2 yl)

Nicotinic Acid: Rats and Rabbits): Report No. A83 30. ( Unpublished study re ceived Oct 6, 1983 under 241 273;

submitted by American Cyanamid Co., Princeton, NJ; CDL: 251502 C)

132032 Voss, K.; Houghtaling, B.; Becci, P. ( 1983) Acute Inhalation Toxi city of AC 243,997 in Sprague Dawley Rats: FDRL Study No. 7624. ( Unpublished study received Oct 6, 1983 under 241 273; prepared by Food & Drug Research Laboratories, Inc., submitted by Ameri can Cyanamid Co., Princeton, NJ; CDL: 251502 D) 64 132359 Hussain, M.; Mallipudi, M. ( 1982) CL 243,997 Herbicide: The Hydrol ysis of Carbon 14 Labeled CL 243,997: Report No. PD M 19 8. ( Unpublished study received Oct 6, 1983 under 241 273; submitted by American Cyanamid Co.,

Princeton, NJ; CDL: 251505 A)

133546 American Cyanamid Co. ( 1983) Toxicology Data: ( AC243,997 & Others). ( Unpublished study received Dec 15, 1983 under 241 EX 101; CDL: 252004 A)

133547 Ledoux, T. ( 1983) Evaluation of the Sensitization Potential of AC 243,997 in Guinea Pigs: T. P. S. Study No. 186A 201

231 83; Spon sor Study No. 981 83 129. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Toxicology Pathology Ser vices, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 F)

133549 Kintner, D.; Forbis, A. ( 1983) Acute Toxicity of AC 243,997 to Bluegill Sunfish ( Lepomis macrochirus): Static Bioassay Report # 30096. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Analytical Bio Chemistry Laboratories, Inc., submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 I)

133550 Kintner, D.; Forbis, A. ( 1983) Acute Toxicity of AC 243,997 to Daphnia magna: Static Bioassay Report # 30098.

( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by An alytical Bio Chemistry Laboratories, Inc.,

submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 K)

133551 Fletcher, D. ( 1983) Report to ...: Acute Oral Toxicity Study with AC 243,997 in Mallard Ducks: AC No. 981 83 115;

BLAL No. 83 DD 16. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyan amid Co., Princeton, NJ; CDL: 252004 L)

133552 Fletcher, D. ( 1983) Report to ...: 8 Day Dietary LC50 Study with AC 243,997 in Bobwhite Quail: BLAL No. 83 QC 23;

AC No. 981 83 114. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Bio Life Assoc., Ltd.,

submitted by American Cyan amid Co., Princeton, NJ; CDL: 252004 M)

133553 Fletcher, D. ( 1983) Report to ...: 8 Day Dietary LC50 Study with AC 243,997 in Mallard Ducklings: BLAL No. 83 DC 23; AC No. 981 83 113. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Bio Life Assoc.,

Ltd., submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 N)

133554 Atkins, E.; Kellum ( 1983) Bee Adult Toxicity Dusting Test Summary: Test No. 389. ( Unpublished study received Dec 15, 1983 under 241 EX 101; prepared by Univ. of California Riverside, Dept. of Entomology, submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 O)

133555 Reichert, B.; Stanley Miller, P. ( 1983) Herbicide AC 243,997: De termination of the Partition Coefficient in n

Octanol/ Water: Report No. PD M Volume 20 10. ( Unpublished study received Dec 15, 1983 under 241 EX 101;

submitted by American Cyanamid Co., Princeton, NJ; CDL: 252004 P) 65 133556 American Cyanamid Co. ( 1983) Product Chemistry: ( AC 243,997 and Others). ( Compilation; unpublished study received Dec 15, 1983 under 241 EX 101; CDL: 252005 A)

133557 American Cyanamid Co. ( 1983) Residue and Environmental Fate:( Arsen al Herbicide ( AC 243,997 & Others).

( Compilation; unpublished study received Dec 15, 1983 under 241 EX 101; CDL: 252006 A)

145872 American Cyanamid Co. ( 19??) Product Chemistry  Technical Materi al [ Arsenal Herbicide]. Unpublished compilation. 163 p.

147049 Fischer, J. ( 1984) Summary of Experimental Results: ( Acute Toxicity: Arsenal Technical): Report No. A84 52.

Unpublished study prepared by American Cyanamid Co. 5 p.

147114 American Cyanamid Co. ( 1985?) Summary: Fish and Wildlife Addition al Data for Full Registration of Arsenal Herbicide for Noncrop Uses. Unpublished study. 2 p.

147118 American Cyanamid Co. ( 1985?) Summary: Environmental Fate Addi tional Data for Full Registration of Arsenal Herbicide for Non crop Uses. Unpublished study. 4 p.

147119 Mallipudi, N. ( 1985) Arsenal Herbicide, AC 243,997: Weed and Soil Metabolism in a Field Plot: Report No. PD M Volume 22 23: 1 89. Unpublished study prepared by American Cyanamid Co. 89 p.

147120 McAllister, W.; Bunch, B.; Burnett, J. ( 1985) Bioconcentration and Depuration of [ Radiolabeled Carbon] AC 243, 997 by Bluegill Sun fish ... under Flow through Conditions: ABC Final Report # 32819. Unpublished study prepared by Analytical Bio Chemistry Laborato ries, Inc. 259 p.

147121 American Cyanamid Co. ( 1985) Product Chemistry: Additional Data for Full Registration of Arsenal Herbicide for Noncrop Uses. Unpub lished compilation. 105 p.

151637 American Cyanamid Co. ( 1985?) Toxicology: Summary and Sample Iden tification and Purity: [ Mutagenicity].

Unpublished study. 8 p.

151638 Enloe, P.; Pfiffner, A.; Salamon, C. ( 1985) Dominant Lethal Assay in Male Rats with AC 243,997: Toxigenics' Study 450 1284: [ In cludes Pilot Study No. 450 1283 by Toxigenics, Inc.]. Unpub lished study prepared by Toxigenics, Inc.

212 p.

151639 Sernau, R. ( 1984) Unscheduled DNA Synthesis Rat Hepatocyte Assay: Compound AC 243,997: Final Report: Project No. 362 170. Unpub lished study prepared by Hazleton Laboratories America, Inc. 18 p. 66 151640 Cortina, T. ( 1984) In vitro Chromosomal Aberrations in Chinese Ham ster Ovary Cells with AC 243,997: Final Report:

362 169. Unpub lished study prepared by Hazleton Laboratories America, Inc. 34 p.

151641 Johnson, E.; Allen, J. ( 1984) Mutagenicity Testing of AC 243,997 in the in vitro CHO/ HGPRT Mutation Assay: Project No. 0493. Unpub lished study prepared by American Cyanamid Co. 39 p.

163194 American Cyanamid Co. ( 1986) Chopper Herbicide: Product Chemistry. Unpublished compilation. 45 p.

163195 Fischer, J. ( 1986) Toxicity Data Report: [ Summary of Experimental Results]: Chopper C/ A Formulation: Report No.

A86 31. Unpub lished summaries prepared by American Cyanamid Co. 5 p.

163196 Hershman, R. ( 1986) Acute Inhalation Toxicity  Rats: Chopper Herbicide: Project No. 86 5095A. Unpublished study prepared by Biosearch Inc. 24 p.

163197 Sahota, P. ( 1986) Dermal Sensitization Study with Chopper Herbicide in Guinea Pigs: DRC 4901. Unpublished study prepared by Dawson Research Corp. 25 p.

40070900 American Cyanamid Co. ( 1987) Registration for Contain Herbicide: Acute Toxicology. Compilation of 1 Study.

40070901 Fisher, J. ( 1986) Contain Acute Toxicology of Herbicide: Laboratory Report No.: A 86 28. Unpublished compilation prepared by Ameri can Cyanamid Co. 10 p.

40387200 American Cyanamid Co. ( 1987) Submission of Chemistry Data to Sup port the Registration for Arsenal 5 G Herbicide for Noncrop and Forestry Usage. Transmittal of 2 studies.

40387201 Beardmore, R. ( 1987) Product Identity and Disclosure of Ingredien ts: Arsenal 5 G. Unpublished study prepared by American Cyana mid Co. 15 p.

40387202 Beardmore, R. ( 1987) Physical Chemical Properties of Arsenal 5 G. Unpublished study prepared by American Cyanamid Co. 4 p.

40403700 American Cyanamid Co. ( 1987) Submission of Residue Data Petition for Exemption from a Food Additive Tolerance for Imazapyr in or on Palm Oil. Transmittal of 3 studies.

40403701 Mallipudi, N. ( 1987) Imazapyr Herbicide ( AC 243, 997): Metabolism of Carbon 14 Imazapyr [ Nicotinic acid, 2( 4

isopropyl 4 methyl 5 oxo 2 yl] in Oil Palm: Laboratory Report No. PD M Volume 23 38. Unpublished study prepared by American Cyanamid Co. 54 p. 67 40403702 Potts, C. ( 1987) Arsenal Herbicide ( CL 243,997/ IPAS AS): Residues of CL 243,997 in Palm Oil Fruit ...: Laboratory Report No.: C 2461. Unpublished study prepared by American Cyanamid Co. 12 p.

40403703 Potts, C. ( 1987) Arsenal Herbicide ( CL 252,925): GC Method for the Determination of CL 243,997 Residues in Oil Palm Fruit: Labora tory Report No. C 2422. Unpublished study prepared by American Cyanamid Co. 13 p.

40421600 American Cyanamid Co. ( 1987) Submission of Residue Data To Support the Application for the Registration of Imazapyr. Transmittal of 1 study.

40421601 Mangels, G. ( 1987) Imazapyr Herbicide ( AC 243,997): Metabolism of Carbon 14 Imazapyr ? Nicotinic Acid, 2( 4

isopropyl 4 methyl 5 oxo 2 yl)| in Sugarcane: Laboratory Report No. PD M Volume 24 19. Unpublished study prepared by American Cyanamid Co. 27 p.

40672700 American Cyanamid Co. ( 1988) Product Chemistry Data submitted for Arsenal Herbicide 0.5G Registration: ? Minor Amendments|. Trans mittal of 1 study.

40672701 Garber, M. ( 1988) Amendments to the Disclosure of Ingredients ... and Certification of Limits: Arsenal Herbicide 0.5G.

Unpub lished study prepared by American Cyanamid Co. 7 p.

40763400 American Cyanamid Co. ( 1988) Submission of Product Chemistry and Toxicity Data to Support the Registration for Event. Transmit tal of 2 studies.

40763401 American Cyanamid Co. ( 1988) Product Identity and Disclosure of Ingredients: Event. Unpublished study. 21 p.

40763402 Lowe, C. ( 1988) Acute Oral, Acute Dermal, Eye Irritation, and Skin Irritation Studies with Event Formulation: Rept. No.

A87 3. Unpublished study prepared by American Cyanamid Co. 8 p.

40811800 American Cyanamid Co. ( 1988) Submission of Environmental Data in Support of Partial Fulfillment of the Unconditional Registration of Imazapyr in Forestry. Transmittal of 2 studies.

40811801 American Cyanamid Co. ( 1988) The Effect of Arsenal on Non target Terrestrial Plants: Tier II. Unpublished compilation.

172 p.

40811802 Hughes, J. ( 1987) The Effect of Arsenal on Non target Aquatic Plants: Tier II: Laboratory Project ID: 0214 67 1100

1,2,3,4. Unpublished compilation prepared by Malcolm Pirnie, Inc. 180 p.

41002300 American Cyanamid Co. ( 1989) Submission of Data To Support Regi stration of Imazapyr: Environmental Fate Study.

Transmittal of 1 study. 68 41002301 American Cyanamid Co. ( 1988) Imazapyr ( AC243,997): Aerobic Aquatic Degradation: Report No. PD M Volume 25 51.

Unpublished study. 33 p.

41023200 American Cyanamid Co. ( 1989) Submission of Data To Support Regi stration of Arsenal Herbicide: Soil Metabolism Data. Transmit tal of 1 study.

41023201 Tollackson, L. ( 1988) Aerobic Soil Metabolism of ? carbon 13|? car bon 14| AC 243,997 in Sandy Loam Soil at 1.5 ppm Concentration at 25 degrees C: Report No. 34927. Unpublished study prepared by ABC Laboratories, Inc. 561 p.

41039500 America Cyanamid Co. ( 1989) Submission of Data To Support Registra tion of Imazapyr ( Arsenal Technical):

Toxicology Data. Trans mittal of 5 studies.

41039501 Harris, J. ( 1989) Imazapyr Toxicology Summary. Unpublished study prepared by American Cyanamid Co. 9 p.

41039502 Shellenberger, T. ( 1987) One Year Dietary Toxicity Study in Pure bred Beagle Dogs with AC 243,997: Report No.

86002. Unpublished study prepared by Tegeris Laboratories, Inc. 685 p.

41039503 Daly, I. ( 1988) A Chronic Dietary Toxicity and Oncogenicity Study with AC 243,997 in Rats: Report No. 84 2862.

Unpublished study prepared by Bio/ dynamics Inc. 3597 p.

41039504 Auletta, C. ( 1988) A Chronic Dietary Toxicity and Oncogenicity Study with AC 243,997 in Mice: Report No. 86 3074.

Unpublished study prepared by Bio/ dynamics Inc. 2795 p.

41039505 Robinson, K. ( 1987) A 2 Generation ( 2 Litter) Reproduction Study of AC 243,997 Administered in the Diet of the Rat:

Report No. 82408. Unpublished study prepared by Bio Research Laboratories Ltd. 1194 p.

41315800 American Cyanamid Co. ( 1989) Submission of studies in support of reregistration for Arsenal ( Imazapyr): Aquatic organism toxi city. Transmittal of 5 studies.

41315801 Manning, C. ( 1989) Acute Toxicity of AC 243,997 to Atlantic Silversides ( Menidia menidia): Final Report: Lab Report No. 87384 0300 2130; AC 243,997/ MM; Protocol 971 87 153. Unpub lished study prepared by Environmental Science and Engineering, Inc. ( ESE). 33 p.

41315802 Ward, C. ( 1989) Acute Toxicity on New Shell Growth of the Eastern Oyster ( Crassostrea virginica): Final Report: Lab Report No. 87384 0400 2130; AC 243,997/ OYS; Protocol 971 87 151. Unpublished study prepared by Environmental Science and Engineering, Inc. ( ESE). 36 p. 69 41315803 Manning, G. ( 1989) Acute Toxicity of AC 243,997 to Pink Shrimp ( Penaeus duoraram): Final Report: Lab Report No.

87384 0200 2130; AC 243,997/ PS; Protocol 971 87 152. Unpublished study prepared by Environmental Science and Engineering, Inc. ( ESE). 33 p.

41315804 Manning, C. ( 1989) Chronic Toxicity Estimate of AC 243,997 to Rainbow Trout ( Salmo gairdneri) under Flow through Conditions: Final Report: Lab Report No. 87384 0600 2130; AC 243,997/ RT; Protocol 971 87 155. Unpublished study prepared by Environ mental Science and Engineering, Inc. ( ESE). 45 p.

41315805 Manning, C. ( 1989) Chronic Effect of AC 243,997 to the Water Flea ( Daphnia magna) in a 21 day Flow through Exposure: Final Report: Lab Report No. 87384 0500 2130; AC 243,997/ DM; Protocol 020F. Unpublished study prepared by Environmental Science and Engineering, Inc. ( ESE). 44 p.

41353400 American Cyanamid Co. ( 1990) Submission of Chemistry and Toxicity Data in Support of Chopper RTU Herbicide Registration. Trans mittal of 9 studies.

41353401 American Cyanamid Co. ( 1989) Product Identity and Disclosure Ingredients: ? Imazapyr|. Unpublished study. 15 p.

41353402 Banick, W. ( 1989) Certification of Limits and Analytical Method: ? Imazapyr|. Unpublished study prepared by American Cyanamid Co. 22 p.

41353403 Peevey, R. ( 1989) Physical and Chemical Properties of Chopper RTU Herbicide. Unpublished study prepared by American Cyanamid Co. 8 p.

41353404 Fischer, J. ( 1989) Oral LD50 Study in Albino Rats with AC 243,997 6% RTU Formulation: Lab Project Number: T 0186:

Report No. A89 205. Unpublished study prepared by American Cyanamid Co. 14 p.

41353405 Fischer, J. ( 1989) Dermal LD50 Study in Albino Rabbits with AC 243,997 6% RTU Formulation: Lab Project Number:

T 0187: Report No. A89 203. Unpublished study prepared by American Cyanamid Co 14 p.

41353406 Fischer, J. ( 1989) Eye Irritation Study in Albino Rabbits with AC 243,997 6% RTU Formulation: Lab Project Number: T

0182: Report No. A89 200. Unpublished study prepared by American Cyanamid Co. 15 p.

41353407 Fischer, J. ( 1989) Skin Irritation Study in Albino Rabbits with AC 243,997 6% RTU Formulation: Lab Project Number:

T 0184: Report No. A89 201. Unpublished study prepared by American Cyanamid Co. 15 p.

41353408 Werley, M. ( 1987) Final Report on a Single Point Inhalation Expo sure to Chopper RTU 6 in Adult Sprague Dawley Rats of Both Sexes: Lab Project Number: MB 87 8931 E. Unpublished study prepared by MB Research Laboratories, Inc.

55 p. 70 41353409 American Cyanamid Co. ( 1988) Dermal Sensitization in Guinea Pigs: Lab Project Number: MB 87 8931 F. Unpublished study prepared by MB Research Laboratories, Inc. 13 p.

41516300 American Cyanamid Co. ( 1990) Submission of Efficacy Study to Sup port the Registration of Imazapyr. Transmittal of 1 study.

41516301 Iverson, R. ( 1990) Discussion and Summary of Reference Articles on Helicopter Spray Drift. Unpublished study prepared by American Cyanamid Co. 41 p.

41664700 American Cyanamid Co. ( 1990) Submission of Product Chemistry Data to Support the Reregistration of ARSENAL.

Transmittal of 1 Study.

41664701 Cortes, D. ( 1990) Phase 3 Summary of MRID # 145872: Imazapyr Phy sical and Chemical Characteristics Solubility in Water and in Solvents: Lab Project Number: PD/ M/ 27/ 36. Unpublished study prepared by American Cyanamid Co. 56 p.

41891500 American Cyanamid Co. ( 1991) Submission of environmental fate data to support an application for nonfood use of Arsenal herbicide. Transmittal of 1 study.

41891501 American Cyanamid Co. ( 1991) Aquatic Dissipation Studies and Rela ted Data ? Arsenal Herbicide|: Lab Project Number: CY 41. 328 p. Unpublished study. 328 p.

42062400 American Cyanamid Co. ( 1991) Submission of toxicity data to support the registration standard for Imazapyr ( Arsenal).

Transmittal of 1 study.

42062401 Daly, I.; Harris, J.; Koeferl, M. ( 1991) A Chronic Dietary Toxicity and Oncogenicity Study with AC 243, 997 in Rats ( Historical Con trol Data): Supplement to MRID 41039503: Lab Project Number: 84 2862. Unpublished study prepared by Bio/ Dynamics Inc. 139 p.

42087300 American Cyanamid Co. ( 1991) Submission of product chemistry data to support the reregistration standard for Imazapyr.

Transmittal of 1 study.

42087301 Cortes, D. ( 1991) Imazapyr Storage Stability and Corrosion Characteristics. Unpublished study prepared by American Cyanamid Co. 27 p.

42165400 American Cyanamid Co. ( 1992) Submission of product chemistry and toxicity data in support of registration of Arsenal ( R)/ Diuron Granule. Transmittal of 9 studies.

42165401 Little, D. ( 1991) Product Identity and Disclosure of Ingred ients, Arsenal/ Diuron Granule. Unpublished study prepared by American Cyanamid Co. 15 p. 71 42165402 Wu, H. ( 1991) Analysis and Certification of Limits, Arsenal/ Diuron Granules. Unpublished study prepared by American Cyanamid Co. 48 p.

42165403 Kimler, J. ( 1991) Physical and Chemical Characterisitics, Arsenal/ Diuron Granule. Unpublished study prepared by American Cyananmid Co. 42 p.

42165404 Lowe, C. ( 1991) Oral LD50 Study in Albino Rats with AC 243, 997/ AC 58,901 ( 0.5%/ 2%) Granular Formulation: Lab Project Number: STUDY T 0363. Unpublished study prepared by American Cyanamid Co. 14 p.

42165405 Lowe, C. ( 1991) Dermal LD50 Study in Albino Rabbits with AC 243, 997/ AC 58,901 ( 0.5%/ 2%) Granular Formulation:

Lab Project Number: STUDY T 0366. Unpublished study prepared by American Cyanamid Co. 14 p.

42165406 Hershman, R. ( 1991) Acute Inhalation Toxicity Study with Imazapyr/ Diuron in Rats: Lab Project Number: 91 7249A.

Unpublished study prepared by Biosearch Inc. 45 p.

42165407 Lowe, C. ( 1991) Eye Irritation Study in Albino Rabbits with AC 243,997/ AC 58,901 ( 0.5%/ 2%) Granular Formulation:

Lab Project Number: STUDY T 0350. Unpublished study prepared by American Cyanamid Co. 15 p.

42165408 Lowe, C. ( 1991) Skin Irritation Study in Albino Rabbits with AC 243,997/ AC 58,901 ( 0.5%/ 2%) Granular Formulation:

Lab Project Number: STUDY T 0352. Unpublished study prepared by American Cyanamid Co. 14 p.

42165409 Lowe, C. ( 1991) Skin Sensitization Study in Albino Guinea Pigs with AC 243,997/ AC 58,901 ( 0.5%/ 2%) Granular Formulation: Lab Project Number: STUDY T 0415. Unpublished study prepared by American Cyanamid Co. 27 p.

42774401 Hess, F. ( 1992) Additional Data on Chronic Toxicology Studies ( Rodent), New Subchronic Rodent Study, and Rationale Supporting the Acceptability of the Chronic Rodent Study: ( including AC 243,997: A 13 week Dietary Toxicity Study in the Albino Rat: Am. Cyanamid Lab report AX 92 3). Unpublished study prepared by American Cyanamid Co. 547 p.

43423700 American Cyanamid Co. ( 1994) Submission of Product Chemistry and Environmental Fate Data in Support of Arsenal Reregistration. Transmittal of 3 Studies.

43423701 Cortes, D.; Chiarello, G. ( 1994) Product Identity, Description of Beginning Materials and Manufacturing Process, and Theoretical Discussion of Impurities of ARSENAL Herbicide Technical: Lab Project Number: APBR 386: CHDV 30

4.1. Unpublished study prepared by American Cyanamid Co. 56 p.

43423702 Danishevsky, V.; Cortes, D. ( 1994) Preliminary Analysis, Certification of Ingredient Limits, and Analytical Method for ARSENAL Herbicide Technical: Lab Project Number: APBR 362: APBR 386. Unpublished study prepared by American Cyanamid Co. 200 p. 72 43423703 Mangels, G. ( 1994) AC 243,997 Adsorption/ Desorption: Lab Project Number: ENV 94 022. Unpublished study prepared by American Cyanamid Co. 41 p.

43578000 American Cyanamid Co. ( 1995) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Arsenal/ Diuron 70 DG Herbicide. Transmittal of 9 Studies.

43578001 Wixson, M. ( 1995) Product Identification and Disclosure of Ingredients, Description of Beginning Materials and Manufacturing Process, Discussion of Formation of Impurities: Arsenal/ Diuron 70 DG Herbicide. Unpublished study prepared by American Cyanamid Co. 15 p.

43578002 Owtscharuk, P.; Banick, W. ( 1995) Certification of Limits and Analytical Methods: Arsenal/ Diuron 70 DG Herbicide:

Lab Project Numbers: C 4109: 94FAI 0493 02. Unpublished study prepared by American Cyanamid Co. 49 p.

43578003 Arendt, V. ( 1994) Physical and Chemical Characteristics: Arsenal/ Diuron 70 DG Herbicide: Lab Project Numbers: F

1291: 94PIF 0493 06. Unpublished study prepared by American Cyanamid Co. 18 p.

43578004 Lowe, C. ( 1994) Oral LD50 in Albino Rats with AC 243,997/ AC 58,901: 70 DG Formulation: Lab Project Numbers: T

0702: A94 239. Unpublished study prepared by American Cyanamid Co. 16 p.

43578005 Lowe, C. ( 1994) Dermal LD50 in Albino Rats with AC 243,997/ AC 58,901: 70 DG Formulation: Lab Project Numbers:

T 0703: A94 240. Unpublished study prepared by American Cyanamid Co. 15 p.

43578006 Hoffman, G. ( 1995) Acute Inhalation Study with AC 243,997/ AC 58,901: 70 DG Formulation in Rats: Lab Project Numbers: 94 5178: 971 94 101: TAN 94 044. Unpublished study prepared by Pharmco LSR. 109 p.

43578007 Boczon, L. ( 1994) Eye Irritation Study in Albino Rats ( sic) with AC 243,997/ AC 58,901: 70 DG Formulation: Lab Project Numbers: T 0700: A94 246: P94 1044. Unpublished study prepared by American Cyanamid Co. 15 p.

43578008 Boczon, L. ( 1994) Skin Irritation Study in Albino Rabbits with AC 243,997/ AC 58,901: 70 DG Formulation: Lab Project Numbers: T 0701: A94 243: P94 1045. Unpublished study prepared by American Cyanamid Co. 16 p.

43578009 Boczon, L. ( 1994) Dermal Sensitization Study in Albino Guinea Pigs with AC 243,997/ AC 58,901: 70 DG Formulation Using the Buehler Closed Patch Method: Lab Project Numbers: T 0707: A94 249: P94 1056. Unpublished study prepared by American Cyanamid Co. 27 p.

43831400 American Cyanamid Co. ( 1995) Submission of Hazard to Wildlife Data in Support of the Reregistration of Arsenal Herbicide. Transmittal of 2 Studies. 73 43831401 Fletcher, D.; Pedersen, C.; Solatycki, A.; et al. ( 1995) Toxicity and Reproduction Study: AC 243,997 Technical:

Bobwhite Quail ( Colinus virginianus): Revised Final Report: Lab Project Number: 991 86 124: 86 QR 16: OREP 856.01.

Unpublished study prepared by Bio Life Associates, Inc. 379 p.

43831402 Fletcher, D.; Pedersen, C.; Solatycki, A.; et al. ( 1995) Toxicity and Reproduction Study: Mallard Duck ( Anas platyrhynchos): AC 243,997 Technical: Revised Final Report: Lab Project Number: 991 86 123: 86 DR 15: OREP 856.01. Unpublished study prepared by Bio Life Associates, Inc. 398 p.

43861500 American Cyanamid Co. ( 1995) Submission of Product Chemistry, Toxicology, Metabolism and Residue Chemistry Data in Support of the Registration of AC 513,996 Herbicide and the Petition for Tolerance for Imazapyr on Field Corn.

Transmittal of 18 Studies.

43861501 Mallipudi, N.; Wu, D. ( 1994) CL 243,997: Rat Metabolism Study: Lab Project Number: RPT0074: MET 94 009:

XBL90045. Unpublished study prepared by Xenobiotic Labs, Inc. and Hazleton Wisconsin, Inc. 520 p.

43861502 Zulalian, J. ( 1995) Imazapyr ( CL 243,997): Metabolism of Carbon 14 Labeled CL 243,997 Using Radishes, Soybeans,

Lettuce and Winter Wheat as Rotational Crops: Lab Project Number: MET 95 003: M93P997NC2: 0462. Unpublished study prepared by American Cyanamid Co. 216 p.

43861503 Zulalian, J. ( 1995) CL 243,997: Metabolism of Carbon 14 Labeled CL 243,997 in Imidazolinone Resistant Corn Under Field Conditions: Lab Project Number: MET 95 002: M93P997NC1: 0462. Unpublished study prepared by American Agricultural Services, Inc. 347 p.

43861504 Zdybak, J. ( 1992) CL 243,997: Carbon 14 Labeled CL 243,997 Derived Residues in Blood, Milk and Edible Tissues of Lactating Goats: Lab Project Number: PD M 29 34: RPT0025: 89020. Unpublished study prepared by Xenobiotic Labs,

Inc. and Biological Test Center. 126 p.

43861505 Tsalta, C. ( 1995) CL 243,997: Metabolic Fate of ( carbon 14) CL 243,997 in Tissues and Eggs of the Laying Hen: Lab Project Number: MET 95 007: M94A997PT1. Unpublished study prepared by American Cyanamid Co. 170 p.

43861506 Frazier, T.; Krueger, R. ( 1995) Product Identification and Disclosure of Ingredients, Decription of Beginning Materials and Manufacturing Process, Discussion of Formation of Impurities: ( AC 513,996 Herbicide). Unpublished study prepared by American Cyanamid Co. 15 p.

43861507 Fletcher, J. ( 1995) CL 243,997: Independent Laboratory Validation of GC/ MS Method M 2468 for the Determination of CL 243,997 Residues in Corn Grain, Forage and Fodder: Lab Project Number: RES 95 080: M 2468: AR94PT02.

Unpublished study prepared by Centre Analytical Labs, Inc. 68 p. 74 43861508 Piznik, M. ( 1995) Certification of Limits and Analytical Methods: ( AC 513,996): Lab Project Number: F 1325: 95FAI

0193 01. Unpublished study prepared by American Cyanamid Co. 48 p.

43861509 Ong, J. ( 1995) Imazethapyr/ Imazapyr 70 DG Herbicide: Physical and Chemical Characteristics: Lab Project Number: F

1341: 95PIF 0193 09. Unpublished study prepared by American Cyanamid Co. 22 p.

43861510 Lowe, C. ( 1995) Oral LD50 Study in Albino Rats with AC 263,499/ AC 243,997 70DG Formulation: Lab Project Number: T 0805: A95 151. Unpublished study prepared by American Cyanamid Co. 18 p.

43861511 Lowe, C. ( 1995) Dermal LD50 Study in Albino Rats with AC 263,499/ AC 243,997 70DG Formulation: Lab Project Number: T 0806: A95 152. Unpublished study prepared by American Cyanamid Co. 18 p.

43861512 Hoffman, G. ( 1995) Acute Inhalation Toxicity Study with AC 263,499/ AC 243,997 70DG in Rats: Lab Project Number:

94 5221. Unpublished study prepared by Pharmaco LSR. 90 p.

43861513 Boczon, L. ( 1995) Eye Irritation Study in Albino Rabbits with AC 263,499/ AC 243,997 70 DG Formulation: Lab Project Number: T 0792: A95 127. Unpublished study prepared by American Cyanamid Co. 17 p.

43861514 Boczon, L. ( 1995) Skin Irritation Study in Albino Rabbits with AC 263,499/ AC 243, 997 70 DG Formulation: Lab Project Number: T 0790: A95 128. Unpublished study prepared by American Cyanamid Co. 15 p.

43861515 Boczon, L. ( 1995) Dermal Sensitization Study in Albino Guinea Pigs with AC 263,499/ AC 243,997 70 DG Formulation Using the Buehler Closed Patch Method: Lab Project Number: A95 111. 01: T 0796. Unpublished study prepared by American Cyanamid Co. 30 p.

43861516 Fletcher, J.; Khunachak, A. ( 1995) CL 243,997: Extractability and Accountability of CL 243,997 Residues in Corn Grain and Plant: Lab Project Number: RES 95 081: AR95PT01. Unpublished study prepared by American Cyanamid Co. 34 p.

43861517 Fletcher, J.; Zheng, S. ( 1995) CL 243,997: Freezer Storage Stability of Residues of CL 243,997 in Corn Commodities ( Grain, Forage, and Fodder): Lab Project Number: RES 95 163: AR94PT01: 007 35. Unpublished study prepared by Centre Analytical Labs, Inc. 52 p.

43861518 Mahl, T. ( 1995) CL 243,997 ( Imazapyr): Crop Residue Study with AC 243,997 on Field Corn: Lab Project Nos.: RES 95

083; RES 95 085; RES 95 086. Unpublished study prepared by Agsearch Co.; Centre Analytical Labs, Inc.; and Agvise Labs. 1702 p.

44027100 American Cyanamid Co. ( 1996) Submission of Toxicology Data in Support of the Application for Registration of AC 513,996. Transmittal of 1 Study. 75 44027101 Boczon, L.; Fischer, J. ( 1995) Eye Irritation Study in Albino Rabbits with AC 263,499/ AC 243,997 70 DG Formulation:

Addendum to MRID 43861513: Lab Project Number: T 0792: A95 127. Unpublished study prepared by American Cyanamid Co. 4 p.

44034500 American Cyanamid Co. ( 1996) Submission of Product Chemistry and Toxicity Data in Support of the Registration Application for AC 513,995 Herbicide. Transmittal of 9 Studies.

44034501 Frazier, T. ( 1996) Product Identification and Disclosure of Ingredients, Description of Beginning Materials and Manufacturing Process, Discussion of Formation of Impurities: AC 513,995 Herbicide. Unpublished study prepared by American Cyanamid Co. 17 p.

44034502 Owtscharuk, P. ( 1996) Certification of Limits and Analytical Methods: AC 513,995 Herbicide: Lab Project Number:

F1353. Unpublished study prepared by American Cyanamid Co. 63 p.

44034503 Ong, J. ( 1996) Imazethapyr/ Imazapyr/ Dicamba DG Herbicide: Physical and Chemical Characteristics: Lab Project Number: F 1357: 0193: 95PIF 0193 13. Unpublished study prepared by American Cyanamid Co. 21 p.

44034504 Lowe, C. ( 1996) Oral LD50 Study in Albino Rats with CL 263,499/ CL 243,997/ CL 350,410 DG Formulation: Lab Project Number: T 0865: A95 220. Unpublished study prepared by American Cyanamid Co. 26 p.

44034505 Lowe, C. ( 1996) Dermal LD50 Study in Albino Rats with CL 263,499/ CL 243,997/ CL 350,410 DG Formulation: Lab Project Number: T 0864: A95 219. Unpublished study prepared by American Cyanamid Co. 20 p.

44034506 Hoffman, G. ( 1996) Acute Inhalation Toxicity Study with CL 263,499/ CL 243,997/ CL 350,410 DG in Rats: Lab Project Number: 95/ 5248: TAN/ 95/ 034: 971/ 95/ 114. Unpublished study prepared by Huntingdon Life Sciences. 80 p.

44034507 Boczon, L. ( 1996) Eye Irritation Study in Albino Rabbits with CL 263,499/ CL 243,997/ CL 350,410 DG Formulation:

Lab Project Number: T/ 0860: A95/ 200. Unpublished study prepared by American Cyanamid Co. 17 p.

44034508 Boczon, L. ( 1996) Skin Irritation Study in Albino Rabbits with CL 263,499/ CL 243,997/ CL 350,410 DG Formulation:

Lab Project Number: T/ 0861: A95/ 199. Unpublished study prepared by American Cyanamid Co. 16 p.

44034509 Glaza, S. ( 1996) Dermal Sensitization Study with CL 263,499/ CL 243,997/ CL 350,410 DG in Guinea Pigs: Lab Project Number: CHW/ 50802096: 971/ 95/ 141: 50802096. Unpublished study prepared by Corning Hazleton Inc. 64 p.

44081900 American Cyanamid Co. ( 1996) Submission of Residue Data in Support of the Application for Registration of AC 513,996 Herbicide and the Petition for Tolerance of Imazapyr on Corn. Transmittal of 1 Study. 76 44081901 Fletcher, J.; Zheng, S.; Zulalian, J. et al. ( 1996) CL 243,997: Freezer Stability of Residues of CL 243,997 in Corn Commodities ( Grain, Forage and Fodder): Addendum: Lab Project Number: RES 95 163: MET 95 002.01: AR94PT01.

Unpublished study prepared by Centre Analytical Labs., Inc. 8 p.

44087700 American Cyanamid Co. ( 1996) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Arsenal 75 SG Herbicide. Transmittal of 9 Studies.

44087701 Birk, J. ( 1995) Arsenal 75 SG Herbicide: Product Identity and Composition. Unpublished study prepared by American Cyanamid Co. 15 p.

44087702 Piznik, M. ( 1996) Arsenal 75 SG Herbicide: Certification of Limits and Analytical Methods: ( Amended Report): Lab Project Number: F 1299: M 1504.02: 94 FAI 0493 08. Unpublished study prepared by American Cyanamid Co. 53 p.

44087703 Arendt, V.; Comisky, S. ( 1995) Arsenal 75 SG Herbicide: Physical and Chemical Characteristics: Lab Project Number: F

1296: 94PIF 0493 14: 0493. Unpublished study prepared by American Cyanamid Co. 18 p.

44087704 Lowe, C.; Bradley, D. ( 1996) Oral LD50 Study in Albino Rats with AC 243,997 75 SG Formulation: ( Arsenal 75 SG):

Lab Project Number: A95 88.01: T 0763. Unpublished study prepared by American Cyanamid Co. 19 p.

44087705 Lowe, C. ( 1995) Dermal LD50 Study in Albino Rats with AC 243,997 75 SG Formulation: ( Arsenal 75 SG): Lab Project Number: T 0769: A95 91. Unpublished study prepared by American Cyanamid Co. 18 p.

44087706 Hoffman, G. ( 1995) Acute Inhalation Study with AC 243,997 75 SG in Rats: ( Arsenal 75 SG): Lab Project Number: 94

5211: 971 94 124: TAN 95 005. Unpublished study prepared by Pharmaco LSR, Inc. 116 p.

44087707 Boczon, L. ( 1995) Eye Irritation Study in Albino Rabbits with AC 243,997 75 SG Formulation: ( Arsenal 75 SG): Lab Project Number: A95 81: T 0766. Unpublished study prepared by American Cyanamid Co. 15 p.

44087708 Boczon, L. ( 1995) Skin Irritation Study in Albino Rabbits with AC 243,997 75 SG Formulation: ( Arsenal 75 SG): Lab Project Number: T 0767: A95 80. Unpublished study prepared by American Cyanamid Co. 15 p.

44087709 Boczon, L. ( 1995) Dermal Sensitization Study in Albino Guinea Pigs with AC 243,997 75 SG Formulation ( Arsenal 75 SG) Using the Buehler Closed Patched Method: Lab Project Number: T 0775: A95 93. Unpublished study prepared by American Cyanamid Co. 27 p.

44102800 American Cyanamid Co. ( 1996) Submission of Residue Data in Support of the Registration and Petition for AC 513996 Herbicide ( Imazapyr) Use in Corn. Transmittal of 1 Study. 77 44102801 Fletcher, J. ( 1996) CL 243,997: Independent Laboratory Validation of CE Method M 2657 for the Determination of CL 243,997 Residues in Corn Grain, Forage and Fodder: Lab Project Number: AR96PT01: RES96 074: 007 85. Unpublished study prepared by Centre Analytical Labs., Inc. 69 p.

44272200 American Cyanamid Co. ( 1997) Submission of Residue Data in Support of the Registration of Lightning Herbicide and Tolerance Petition for Imazapyr in/ on Corn. Transmittal of 1 Study.

44272201 Fletcher, J.; Picard, J. ( 1997) CL 243,997: Freezer Stability of Residues of CL 243,997 in Corn Commodities ( Grain,

Forage and Fodder): Final Report: Lab Project Number: RES 97 016: AR94PT01: P94 1068. Unpublished study prepared by Centre Analytical Labs., Inc. 56 p.

44341400 American Cyanamid Co. ( 1997) Submission of Product Chemistry Data in Support of the Reregistration of Imazapyr Containing Product Arsenal Railroad Herbicide. Transmittal of 1 Study.

44341401 Chiarello, G. ( 1995) Arsenal Technical ( AC 243997) Grade Active Ingredient Thermal Stability to Metals at Elevated Temperatures and Stability when Exposed to Artificial Sunlight: ( Final Report): Lab Project Number: P 141: 94 PROC

0196 6: P 139. Unpublished study prepared by American Cyanamid Co. 44 p.

44626700 American Cyanamid Company ( 1998) Submission of Product Chemistry Data in Support of the Registration of Lightning Herbicide. Transmittal of 1 Study.

44626701 Steller, W. ( 1998) Discussion of the Formation of Impurities of Lightning Herbicide. Unpublished study prepared by American Cyanamid Company. 7 p. { OPPTS 830.1670}

44630800 American Cyanamid Company ( 1998) Submission of Product Chemistry Data in Support of the Registration of Arsenal 75SG Herbicide. Transmittal of 1 Study.

44630801 Steller, W. ( 1998) Discussion of the Formation of Impurities of Arsenal 75SG Herbicide. Unpublished study prepared by American Cyanamid Company. 7 p. { OPPTS 830.1670}

44642900 American Cyanamid Company ( 1998) Submission of Product Chemistry Data in Support of the Registration of Sahara DG Herbicide. Transmittal of 1 Study.

44642901 Steller, W. ( 1998) Discussion of the Formation of Impurities of Sahara DG Herbicide. Unpublished study prepared by American Cyanamid Company. 7 p. { OPPTS 830.1670}

44735300 American Cyanamid Company ( 1999) Submission of Toxicity Data in Support of the Reregistration of Arsenal Herbicide Technical. Transmittal of 1 Study. 78 44735301 Lowe, C. ( 1999) Oral LD50 Study in Albino Rats with AC 243997: Lab Project Number: A98 90: T 1076. Unpublished study prepared by American Cyanamid Company. 17 p. { OPPTS 870.1100}

44746700 American Cyanamid Company ( 1999) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide. Transmittal of 3 Studies.

44746701 Stout, S.; Folmar, K. ( 1999) CL 263499 ( Imazethapyr): Independent Laboratory Validation of LC/ MS Determinative Method M 3119 for Residues of CL 263499 in Water: Lab Project Number: RES 98 081. Unpublished study prepared by Centre Analytical Laboratories, Inc. 60 p.

44746702 Mangels, G.; Brandt, J.; Carver, L. ( 1999) Site Characterization and Instrumentation Report: A Small Scale Prospective Ground Water Monitoring Study for Imazethapyr on Corn in the Midwestern United States: Lab Project Number: EEA 98 03: EXA 99 003. Unpublished study prepared by Centre Analytical Laboratories, Inc. and Agvise Laboratories, Inc.

138 p.

44746703 Mangels, G.; Erbe, M.; Carver, L. ( 1999) Site Characterization and Instrumentation Report: A Small Scale Prospective Ground Water Monitoring Study for Imazethapyr on Corn in the Southeastern United States: Lab Project Number: EEA 98 04: EXA 99 002. Unpublished study prepared by Centre Analytical Laboratories, Inc. and Agvise Laboratories, Inc.

142 p.

44761300 American Cyanamid Company ( 1999) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Liquid Lightning Herbicide. Transmittal of 9 Studies.

44761301 White, R. ( 1998) Product Identification and Disclosure of Ingredients, Description of Beginning Materials and Manufacturing Process, Discussion of Formation of Impurities: Liquid Lightning Herbicide. Unpublished study prepared by American Cyanamid Company. 15 p.

44761302 Zeng, M. ( 1998) Certification of Limits and Analytical Methods: Liquid Lightning Herbicide: Lab Project Number: F

1404. Unpublished study prepared by American Cyanamid Company. 54 p.

44761303 Johnson, J.; Kovacs, G.; Sweetapple, G. ( 1998) Liquid Lightning Herbicide: Physical and Chemical Characteristics: Lab Project Number: F 1407: 1857 98 0120 AS 001. Unpublished study prepared by American Cyanamid Company and Analytical Services. 5 p.

44761304 Lowe, C. ( 1998) Oral LD50 Study in Albino Rats with AC 263499/ AC 243997 1.8 AS: Liquid Lightning Herbicide: Lab Project Number: A98 60. Unpublished study prepared by American Cyanamid Company. 20 p. 79 44761305 Lowe, C.; Bradley, D. ( 1998) Dermal LD50 Study in Albino Rats with AC 263499/ AC 243997 1.8 AS: Liquid Lightning Herbicide: Lab Project Number: A98 73. Unpublished study prepared by American Cyanamid Company. 20 p.

44761306 Hoffman, G. ( 1998) Acute Inhalation Toxicology Study with AC 263499/ AC 243997 1.8 AS in Rats: Liquid Lightning Herbicide: Lab Project Number: 98 5352. Unpublished study prepared by Huntington Life Sciences. 63 p.

44761307 Boczon, L. ( 1998) Primary Eye Irritation Study in Albino Rats with AC 263499/ AC 243997 1.8 AS: Liquid Lightning Herbicide: Lab Project Number: A98 55: T 1063. Unpublished study prepared by American Cyanamid Company. 19 p.

44761308 Boczon, L. ( 1998) Primary Dermal Irritation Study in Albino Rats with AC 263499/ AC 243997 1.8 AS: Liquid Lightning Herbicide: Lab Project Number: A98 59: T 1064. Unpublished study prepared by American Cyanamid Company. 18 p.

44761309 Blanset, D. ( 1998) Dermal Sensitization Study with AC 263499/ AC 243997 1.8 AS in Guinea Pigs Buehler Method ( Nine Inductions): Liquid Lightning Herbicide: Lab Project Number: 98 1792. Unpublished study prepared by Huntington Life Sciences. 43 p.

44865100 American Cyanamid Company ( 1999) Submission of Environmental Fate and Residue Chemistry Data in Support of the Registration of Lightning Herbicide. Transmittal of 3 Studies.

44865101 Carver, L.; Johnson, L.; Kleiner, A. ( 1999) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States: First Progress Report: Lab Project Number: 44657: 007 202: EXA 99 015.

Unpublished study prepared by Research Options, Inc. and ABC Labs. 114 p.

44865102 Carver, L.; Johnson, L.; Kleiner, A. ( 1999) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Midwestern United States: First Progress Report: Lab Project Number: 44656: 007 198: EXA 99 014.

Unpublished study prepared by Research Options, Inc. and ABC Labs. 112 p.

44865103 Cavalier, T. ( 1997) CL 263499( Imazethapyr): Independent Laboratory Validation of Capillary Electrophoresis ( CE)

Determinative and LC/ MS Confirmatory Method M 2683 for the Determination of CL 263499 Residues in Soil: Lab Project Number: RES 97 059. Unpublished study prepared by Centre Analytical Laboratories, Inc. 112 p.

44975000 American Cyanamid Company ( 1999) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide. Transmittal of 1 Study.

44975001 Carver, L.; Johnson, L.; Kleiner, A. ( 1999) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Georgia): Lab Project Number: 44657: 007 202: EXA 99 022. Unpublished study prepared by ABC Labs, Inc., and Research Options, Inc. 161 p. { OPPTS 840.2100} 80 45035200 American Cyanamid Co. ( 1999) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide. Transmittal of 1 Study.

45035201 Pease, C.; Johnson, L.; Kleiner, A. ( 1999) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Midwestern United States ( Indiana): Second Progress Report: Lab Project Number: 44656: 007 198: EXA

99 021. Unpublished study prepared by ABC Labs. and Centre Analytical Labs., Inc. 163 p. { OPPTS 840.2100}

45119700 American Cyanamid Company ( 2000) Submission of Environmental Fate, Residue and Toxicology Data in Support of the Petition for Tolerances of Imazapyr for Aquatic Uses and for Use on Grass. Transmittal of 23 Studies.

45119701 Ta, C. ( 1999) AC 243997: Aerobic Soil Metabolism: Lab Project Number: ENV 98 029: E 98 029. Unpublished study prepared by American Cyanamid Company. 72 p.

45119702 Ta, C. ( 1999) CL 119060 and CL 9140: Aerobic Aquatic Metabolism: Lab Project Number: ENV 98 018: E 98 018.

Unpublished study prepared by American Cyanamid Company. 158 p.

45119703 Borysewicz, R.; Corbett, M.; Duan, B.; et al. ( 2000) Methods of Analysis of Imazapyr Residue in Soil and Pond Water:

Lab Project Number: RES 98 047: RES 98 152: RES 99 127. Unpublished study prepared by American Cyanamid Company and Centre Analytical Labs, Inc. 255 p.

45119704 Khunachak, A.; Ouyang, Z.; Singh, S.; et al. ( 1999) Freezer Storage Stability of Imazapyr Residue in Soil, Sediment, and Pond Water: Lab Project Number: RES 99 056: RES 99 052: RES 99 053. Unpublished study prepared by American Cyanamid Company and Centre Analytical Labs, Inc. 245 p.

45119705 Holman, J. ( 2000) AC 243997 ( Imazapyr) and Metabolites: Adsorption/ Desorption on Sediments: Lab Project Number:

ENV 98 025: E 98 025. Unpublished study prepared by American Cyanamid Company. 97 p.

45119706 Garrett, A. ( 2000) Rate of Dissipation of Soil Residues of Imazapyr: Lab Project Number: RES 99 108: RES 99 109:

AR96IA01. Unpublished study prepared by American Cyanamid Company, Centre Analytical Labs, Inc., and Midwest Research, Inc. 333 p.

45119707 Borysewicz, R. ( 1999) Residues of CL 243997, CL 9140, and CL 119060 in Aquatic Field Dissipation and Aquatic Non

Target Organisms for Arsenal Herbicide Applied to Freshwater Ponds: Lab Project Number: RES 99 059: RES 99 060:

AR96FL01. Unpublished study prepared by American Cyanamid Company, Centre Analytical Labs Inc., Florida Pesticide Research, and Maxim Technologies, Inc. 681 p. 81 45119708 Mangels, G.; Ritter, A.; Safarpour, M. ( 2000) Estimated Environmental Concentrations of Imazapyr Resulting from Aquatic Uses of Arsenal Herbicide: Lab Project Number: EXA 00 008. Unpublished study prepared by American Cyanamid Company. 346 p.

45119709 Drottar, K.; Swigert, J.; Wisk, J. ( 1996) Uptake, Depuration, Bioconcentration, and Metabolism of ( carbon 14) AC 243997 in Eastern Oyster and Grass Shrimp: Lab Project Number: 954 93 165: ECO 93 165.01: 954 93 164.

Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd. 228 p.

45119710 Drottar, K.; Olivieri, C.; Swigert, J. et al. ( 1997) Effect of AC 243997 on 96 Hour Shell Deposition in the Eastern Oyster ( Crassosstrea virginica) Under Flow Through Test Conditions: Lab Project Number: ECO 97 139: 130A 111: 197.05.

Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd. 64 p. { OPPTS 850.1025}

45119711 Drottar, K.; Olivieri, C.; Swigert, J. et al. ( 1998) Toxicity of AC 243997 During the Early Life Stages of the Fathead Minnow ( Pimephales promelas): Lab Project Number: ECO 97 102: 954 97 137: 197.05. Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd. 154 p. { OPPTS 850.1400}

45119712 Drottar, K.; Olivieri, C.; Krueger, H. ( 1999) Toxicity of AC 243997 ( Imazapyr) Technical during the Full Life Cycle of the Fathead Minnow ( Pimephales promelas) under Flow Through Test Conditions: Lab Project Number: ECO 97 101:

130A 113: 954 97 101. Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd.

176 p. { OPPTS 850.1500}

45119713 Drottar, K.; Swigert, J.; Wisk, J. ( 1995) Acute Toxicity of Arsenal Herbicide to the Rainbow Trout ( Oncorhynchus mykiss) Under Flow Through Test Condition: Lab Project Number: 954 94 127: 130A 107: 0199. Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd. 73 p. { OPPTS 850.1075}

45119714 Ahmed, M.; Kapustka, L.; Wisk, J. ( 1999) Avian Reproduction Studies on AC 243997 Technical: Lab Project Number:

ECO 97 147: ECO 97 146: 954 97 147. Unpublished study prepared by American Cyanamid Company and Wildlife International Ltd. 362 p. { OPPTS 850.2300}

45119715 Wu, D. ( 1997) AC 243997: Metabolism in Bermuda Grass Under Field Conditions: Lab Project Number: MET 96 007:

RPT0084: XBL 91041. Unpublished study prepared by American Cyanamid Company, Pan Agricultural Lab Inc., and XenoBiotic Labs Inc. 221 p. { OPPTS 860.1300}

45119716 Tsalta, C. ( 2000) CL 243997: Metabolism of ( carbon 14) CL 243997 in the Lactating Goat: Lab Project Number: MET 00 002: M99A997PT1. Unpublished study prepared by American Cyanamid Company. 160 p. { OPPTS 860.1300,

860.1340} 82 45119717 Mallipudi, N. ( 2000) Imazapyr ( AC 243997): Confined Rotational Crop Study with ( Carbon 14) Labled AC 243997: Lab Project Number: MET 00 003: M97P997NC1: 0527. Unpublished study prepared by American Cyanamid Company and American Agricultural Services, Inc. 338 p. { OPPTS 860.1850}

45119718 Bixler, T.; Fletcher, J.; Gross, J. et al. ( 1999) Validations of Methods of Analysis of Imazapyr Residues in Grass, Cattle Tissue and Milk, Fish, and Shellfish: Lab Project Number: RES 99 001: RES98 108: RES 99 002. Unpublished study prepared by American Cyanamid Company, ABC Labs Inc., and Maxim Tech Inc. 422 p. { OPPTS 860.1340}

45119719 Bixler, T.; Fletcher, J.; Khunachak, A.; et al. ( 2000) Freezer Storage Stability of Imazapyr Residues in Cattle Tissue,

Milk, and Fish: Lab Project Number: RES 99 035: RES 99 031: RES 99 064.01. Unpublished study prepared by American Cyanamid Company, ABC Labs Inc., and Maxim Tech Inc. 102 p. { OPPTS 860.1380}

45119720 Garrett, A.; Baragary, N.; Khunachak, A. ( 1999) Magnitude of Residues of Imazapyr in Grass after Treatment with Arsenal Herbicide: Lab Project Number: RES 98 038: RES 98 039: RES 99 017. Unpublished study prepared by American Cyanamid Company, ABC Labs Inc., AgSearch Company, and AgSolutions Inc. 1147 p. { OPPTS 860.1500}

45119721 Khunachak, A. ( 1999) Arsenal ( Imazapyr CL 243997): Magnitude of CL 243997 in Milk, Milk Fat and Edible Tissues from Dairy Cattle After Oral Administration for at Least 28 Days: Lab Project Number: RES 99 100: AR97PT07: 44390.

Unpublished study prepared by American Cyanamid Company, ABC Labs Inc., Fort Dodge Animal Health, and Maxim Technologies. 232 p. { OPPTS 860.1480}

45119722 Christensen, G.; Madsen, T.; Skorczynski, S.; et al. ( 1999) Field Accumulation Study of Arsenal Herbicide in Freshwater Clam: Lab Project Number: ECO 98 197: 44881: 954 98 1973. Unpublished study prepared by American Cyanamid Company and ABC Laboratories, Inc. 62 p.

45119723 Lowe, C. ( 2000) Acute Oral LD50 Studies in Albino Rats with AC 119060 and AC 9140: Lab Project Number: T 0255:

T 0256: A90 133.01. Unpublished study prepared by American Cyanamid Company. 32 p. { OPPTS 870.1100}

45139100 American Cyanamid Company ( 2000) Submission of Environmental Fate Data in Support of the Application for Registration of Lightning Herbicide. Transmittal of 2 Studies.

45139101 Carver, L.; Johnson, L.; Kleiner, A. ( 2000) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Georgia): Fourth Progress Report: Lab Project Number: 007 202: EXA 99

022.02: EEA 98 04. Unpublished study prepared by Research Options, Inc. and ABC Laboratories. 137 p.

45139102 Carver, L.; Johnson, L.; Kleiner, A. ( 2000) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Midwestern United States ( Indiana): Fourth Progress Report: Lab Project Number: 44656: 007 198: EXA 99

021.02. Unpublished study prepared by AgSearch Company and ABC Laboratories. 188 p. 83 45212600 BASF Corporation ( 2000) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide.

Transmittal of 2 Studies.

45212601 Carver, L.; Johnson, L.; Kleiner, A. ( 2000) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Georgia)( Lightning Herbicide): Lab Project Number: 007 202: EXA 99 022.03.

Unpublished study prepared by Research Options, Inc., ABC Laboratories, and Centre Analytical Laboratories, Inc. 143 p.

{ OPPTS 840.2100}

45212602 Carver, L.; Johnson, L.; Kleiner, A. ( 2000) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Midwestern United States ( Indiana)( Lightning Herbicide): Lab Project Number: 44656. Unpublished study prepared by AgSearch Company, ABC Laboratories, and Centre Analytical Laboratories, Inc. 196 p. { OPPTS 840.2100}

45215100 BASF Corporation ( 2000) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of AC 1014109 Herbicide. Transmittal of 9 Studies.

45215101 Arthur, J. ( 2000) Product Identification and Disclosure of Ingredients, Description of Beginning Materials and Manufacturing Process, Discussion of Formation of Impurities: AC 1014109 Herbicide. Unpublished study prepared by BASF Corporation. 16 p. { OPPTS 830.1550, 830.1600, 830.1650, 830.1670}

45215102 Arthur, J.; Safarpour, H.; Piznik, M. ( 2000) Certification of Limits and Analytical Methods: AC 1014109 Herbicide: Lab Project Number: F1445/ F1299: 99FA 0224 03: 0224. Unpublished study prepared by BASF Corporation. 99 p. { OPPTS 830.1750, 830.1800}

45215103 Foitou, F. ( 2000) Summary of the Physical Chemical Properties of AC 1014109 Herbicide: Lab Project Number: F 1452.

Unpublished study prepared by BASF Corporation. 5 p. { OPPTS 830.6302, 830.6303,830.6314, 830.6315, 830.6316,

830.6320, 830.7000, 830.7100, 830.7300}

45215104 Mason, S. ( 1998) Acute Oral Toxicity Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Rats: Lab Project Number:

CYD 606/ 982980/ AC: CYD 606. Unpublished study prepared by Huntingdon Life Sciences Ltd. 49 p. { OPPTS 870.1100}

45215105 Mason, S. ( 1998) Acute Dermal Toxicity Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Rats: Lab Project Number:

CYD 607/ 982981/ AC: CYD 607. Unpublished study prepared by Huntingdon Life Sciences Ltd. 47 p. { OPPTS 870.1200}

45215106 Hoffman, G. ( 2000) Acute Inhalation Toxicity Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Rats: Lab Project Number: 00 5437: TOX 00 114. Unpublished study prepared by Huntingdon Life Sciences Ltd. 92 p. { OPPTS 870.1300} 84 45215107 Mason, S. ( 1998) Primary Eye Irritation Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Rabbits: Lab Project Number:

CYD 609/ 983013/ SE: CYD 609. Unpublished study prepared by Huntingdon Life Sciences Ltd. 49 p. { OPPTS 870.2400}

45215108 Mason, S. ( 1998) Primary Dermal Irritation Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Rabbits: Lab Project Number: CYD 608/ 982716/ SE: CYD 608. Unpublished study prepared by Huntingdon Life Sciences Ltd. 40 p. { OPPTS 870.2500}

45215109 Coleman, D. ( 1998) Closed Patch Dermal Sensitization Study with Imazapyr/ Glyphosate 75/ 180 g/ l AS in Guinea Pigs:

Lab Project Number: CYD 610/ 983102/ SS: CYD 610. Unpublished study prepared by Huntingdon Life Sciences Ltd. 59 p. { OPPTS 870.2600}

45335300 BASF Corporation ( 2001) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide.

Transmittal of 2 Studies.

45335301 Carver, L.; Johnson, L.; Kleiner, A. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States( Georgia): Lab Project Number: 007 202: EXA 99 022.04. Unpublished study prepared by Research Options, Inc. and Waterborne Environmental, Inc. 98 p. { OPPTS 840.2100}

45335302 Carver, L.; Johnson, L.; Kleiner, A. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States( Indiana): Lab Project Number: 007 198: EXA 99 021.04. Unpublished study prepared by Agsearch Company Waterborne Environmental, Inc. 176 p. { OPPTS 840.2100}

45410000 BASF Corporation ( 2001) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide.

Transmittal of 2 Studies.

45410001 Carver, L.; Johnson, L.; Kleiner, A. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Georgia): Lab Project Number: EXA 99 022.05. Unpublished study prepared by Research Options, Inc. and Waterborne Environmental, Inc. 71 p. { OPPTS 840.2100}

45410002 Carver, L.; Johnson, L.; Kleiner, A. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Indiana): Lab Project Number: 007 198: EXA 99 021.05. Unpublished study prepared by Agsearch Company and Waterborne Environmental, Inc. 136 p.

45498200 BASF Agro Research ( 2001) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide. Transmittal of 2 Studies. 85 45498201 Carver, L.; Johnson, L.; Leonard, R. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Southeastern United States ( Georgia): Eighth Progress Report: Lab Project Number: EXA 99 022.06: EEA 98 04: XA 99 022.06. Unpublished study prepared by Research Options, Inc., Waterborne Environmental, Inc., ABC Laboratories, and Exygen Research. 92 p. { OPPTS 840.2100}

45498202 Carver, L.; Johnson, L.; Leonard, R. ( 2001) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr on Corn in the Midwestern United States ( Indiana): Eighth Progress Report: Lab Project Number: EXA 99 021.06: EEA

98 03: 263.08. Unpublished study prepared by Agsearch Company, Waterborne Environmental, Inc., ABC Laboratories,

and Exygen Research. 100 p. { OPPTS 840.2100}

45663800 BASF Corp. ( 2002) Submission of Environmental Fate Data in Support of the Registration of Lightning Herbicide.

Transmittal of 2 Studies.

45663801 Carver, L.; Johnson, L.; Leonard, R. ( 2002) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr ( BAS 685H) on Corn in the Southeastern United States ( Georgia): Lab Project Number: EXA 99 022.08: EEA 98 04:

RAN 01 016. Unpublished study prepared by Research Options, Inc. 118 p. { OPPTS 840.2100}

45663802 Carver, L.; Johnson, L.; Leonard, R. ( 2002) A Small Scale Prospective Groundwater Monitoring Study for Imazethapyr ( BAS 685H) on Corn in the Midwestern United States ( Indiana): Lab Project Number: EXA 99 021.08: EEA 98 03:

263.08. Unpublished study prepared by AGSEARCH Co. 183 p. { OPPTS 840.2100}

45677400 BASF Agro Research ( 2002) Submission of Environmental Fate Data in Support of the Registration of LIGHTNING Herbicide. Transmittal of 1 Study.

45677401 Jackson, S. ( 2002) Summary Report: Request for Termination of Imazethapyr Prospective Groundwater Studies at Two Sites: Lab Project Number: 2002/ 5002811. Unpublished study prepared by BASF Agro Research. 34 p. { OPPTS 840.2100}

46274400 BASF Corporation ( 2004) Submission of Product Chemistry Data In Support of the Registration of Arsenal Herbicide Technical. Transmittal of 3 Studies.

46274401 Birk, J. ( 2004) Analysis of Imazapyr Herbicide Technical. Unpublished study prepared by BASF Corporation. 7 p.

46274402 Birk, J. ( 2004) Certified Limits: ( Imazapyr Herbicide Technical). Unpublished study prepared by BASF Corporation. 17 p. 86 46274403 Cortes, D. ( 2004) BAS 693 H, Imazapry Technical ( Arsenal Technical, AC 243,997): Discussion of Formation of Impurities. Project Number: 2004/ 5000054. Unpublished study prepared by BASF Corporation. 40 p.

46559100 Agan Chemical Mfg, Ltd. ( 2005) Submission of Product Chemistry Data in Support of the Application for Registration of Imazapyr Technical. Transmittal of 4 Studies.

46559101 Gorban, I. ( 2005) Imazapyr Technical ( Agan)  Product Properties. Project Number: 90007803. Unpublished study prepared by Makhteshim Agan of North America, Inc. and Agan Chemical Manufacturers, Ltd. 105 p.

46559102 Gorban, I. ( 2005) Imazapyr Technical ( Agan)  Five Lots Analysis and Method Validation. Project Number: 04/ 11/ 3,

90007751. Unpublished study prepared by Agan Chemical Manufacturers, Ltd. 95 p.

46559103 Gorban, I. ( 2005) Imazapyr Technical ( NUT)  Product Properties. Project Number: 90007804. Unpublished study prepared by Makhteshim Agan of North America, Inc. and Agan Chemical Manufacturers, Ltd. 113 p.

46559104 Gorban, I. ( 2005) Imazapyr Technical ( NUT)  Five Lots Analysis and Method Validation. Project Number: 04/ 11/ 4,

90007752. Unpublished study prepared by Agan Chemical Manufacturers, Ltd. 95 p.

46624600 Etigra, LLC ( 2005) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Imazapyr Technical. Transmittal of 10 Studies.

46624601 Kay, J. ( 2005) Product Identity and Composition, Description of the Materials Used, Description of the Production Process, Discussion of the Formation of impurities, and Certified Limits for Imazapyr Technical. Project Number:

ET/ 200522. Unpublished study prepared by Etigra, LLC, C/ O Pyxis Regulatory Consulting, Inc. 72 p.

46624602 Jian, Y. ( 2005) Preliminary Analysis of Imazapyr Technical. Project Number: NC/ 2005/ 002. Unpublished study prepared by Nutrichem Laboratory Co. Ltd. 65 p.

46624603 Jian, Y. ( 2005) Chemical and Physical Characteristics of Imazapyr Technical: Color, Physical State, Odor, Stability,

Oxidation/ Reduction, pH, UV Vis, Melting Point, Density, Dissociation Constant, Partition Coefficient, Solubility and Vapor Pressure. Project Number: NC/ 2005/ 003. Unpublished study prepared by Nutrichem Laboratory Co. Ltd. 84 p.

46624604 Kay, J. ( 2005) Waiver Request for Certain Data Requirements for Imazapyr Technical. Project Number: ET/ 200523.

Unpublished study prepared by Etigra, LLC, C/ O Pyxis Regulatory Consulting, Inc. 6 p.

46624605 Mukherjee, A. ( 2005) Acute Oral Toxicity of Imazapyr Technical in Rats. Project Number: 5264. Unpublished study prepared by Jai Research Foundation. 38 p. 87 46624606 Mukherjee, A. ( 2005) Acute Dermal Toxicity Study of Imazapyr Technical in Rats. Project Number: 5265. Unpublished study prepared by Jai Research Foundation. 39 p.

46624607 Mukherjee, A. ( 2005) Acute Inhalation Toxicity Study of Imazapyr Technical in Rats. Project Number: 5269.

Unpublished study prepared by Jai Research Foundation. 54 p.

46624608 Mukherjee, A. ( 2005) Acute Eye Irritation Study of Imazapyr Technical in Rabbits. Project Number: 5267. Unpublished study prepared by Jai Research Foundation. 37 p.

46624609 Mukherjee, A. ( 2005) Acute Dermal Irritation Study of Imazapyr Technical in Rabbits. Project Number: 5266.

Unpublished study prepared by Jai Research Foundation. 34 p.

46633300 Etigra, LLC ( 2005) Submission of Toxicity Data in Support of the Application for Registration of Imazapyr Technical.

Transmittal of 1 Study.

46633301 Mukherjee, A. ( 2005) Skin Sensitization Study of Imazapyr Technical in Guinea Pigs ( Guinea Pig Maximization Test).

Project Number: 5268. Unpublished study prepared by Jai Research Foundation. 53 p.

46683900 PBI/ Gordon Corporation ( 2005) Submission of Product Chemistry Data in Support of the Amended Registration of EH 1135 PGR. Transmittal of 1 Study.

46683901 Sanson, D. ( 2005) Product Identity and Composition of EH 1135 PGR. Unpublished study prepared by PBI/ Gordon Corp.

10 p.

46731400 Agan Chem MFG, Ltd ( 2006) Submission of Product Chemistry Data in Support of the Application for Registration of Imazapyr Technical. Transmittal of 1 Study.

46731401 Gorban, I. ( 2006) Imazapyr Technical  Product Properties ( NUT) ( AGAN). Project Number: JR/ 1/ 9/ 06. Unpublished study prepared by Agan Chem MFG, Ltd. 10 p.

46775500 Vegetation Management, LLC ( 2006) Submission of Product Chemistry and Toxicity Data in Support of the Application for Registration of Mohave 70 EG. Transmittal of 7 Studies.

46775502 Woolley, A.; Mullee, D. ( 2005) Determination of Physico Chemical Properties: Mohave 70 EG: AGN SAH02. Project Number: 008/ 595. Unpublished study prepared by Safepharm Laboratories Ltd. 22 p.

46775503 Sanders, A. ( 2005) Acute Oral Toxicity in the Rat  Up and Down Procedure: Mohave 7 EG: AGN SAH02. Project Number: 008/ 596. Unpublished study prepared by Safepharm Laboratories Ltd. 16 p. 88 46775504 Sanders, A. ( 2005) Acute Dermal Toxicity ( Limit Test) in the Rat: Mohave 70 EG: AGN SAH02. Project Number:

008/ 598. Unpublished study prepared by Safepharm Laboratories Ltd. 19 p.

46775505 Griffiths, D. ( 2005) Acute Inhalation Toxicity ( Nose Only) Study in the Rat: AGN SAH02. Project Number: 008/ 597.

Unpublished study prepared by Safepharm Laboratories Ltd. 32 p.

46775506 Sanders, A. ( 2005) Acute Eye Irritation in the Rabbit: Mohave 7 EG: AGN SAH02. Project Number: 008/ 600.

Unpublished study prepared by Safepharm Laboratories Ltd. 18 p.

46775507 Sanders, A. ( 2005) Acute Dermal Irritation in the Rabbit: AGN SAH02. Project Number: 008/ 599. Unpublished study prepared by Safepharm Laboratories Ltd. 14 p.

46775508 Hathorn, S. ( 2005) Skin Sensitisation in the Guinea Pig Buehler Test Method: Mohave 70 EG: AGN SAH02. Project Number: TL/ 277/ 05/ 1690, 0008/ 601. Unpublished study prepared by Safepharm Laboratories Ltd. 25 p. 89 Appendix E. GENERIC DATA CALL IN Note that a complete Data Call In ( DCI), with all pertinent instructions, will be sent to registrants under separate cover. 90 Appendix F. PRODUCT SPECIFIC DATA CALL IN Note that a complete Data Call In ( DCI), with all pertinent instructions, will be sent to registrants under separate cover. 91 Appendix G. EPA'S BATCHING OF IMAZAPYR PRODUCTS FOR MEETING ACUTE TOXICITY DATA REQUIREMENTS FOR REREGISTRATION In an effort to reduce the time, resources and number of animals needed to fulfill the acute toxicity data requirements for reregistration of products containing IMAZAPYR as the active ingredient, the Agency has batched products which can be considered similar for purposes of acute toxicity. Factors considered in the sorting process include each product's active and inert ingredients ( identity, percent composition and biological activity), type of formulation ( e. g., emulsifiable concentrate, aerosol, wettable powder, granular, etc.), and labeling ( e. g., signal word, use classification, precautionary labeling, etc.). Note that the Agency is not describing batched products as " substantially similar" since some products within a batch may not be considered chemically similar or have identical use patterns.

Using available information, batching has been accomplished by the process described in the preceding paragraph. Notwith standing the batching process, the Agency reserves the right to require, at any time, acute toxicity data for an individual product should the need arise.

Registrants of products within a batch may choose to cooperatively generate, submit or cite a single battery of six acute toxicological studies to represent all the products within that batch. It is the registrants' option to participate in the process with all other registrants, only some of the other registrants, or only their own products within a batch, or to generate all the required acute toxicological studies for each of their own products. If a registrant chooses to generate the data for a batch, he/ she must use one of the products within the batch as the test material. If a registrant chooses to rely upon previously submitted acute toxicity data, he/ she may do so provided that the data base is complete and valid by today's standards ( see acceptance criteria attached), the formulation tested is considered by EPA to be similar for acute toxicity, and the formulation has not been significantly altered since submission and acceptance of the acute toxicity data. Regardless of whether new data is generated or existing data is referenced, registrants must clearly identify the test material by EPA Registration Number. If more than one confidential statement of formula ( CSF) exists for a product, the registrant must indicate the formulation actually tested by identifying the corresponding CSF.

In deciding how to meet the product specific data requirements, registrants must follow the directions given in the Data Call In Notice and its attachments appended to the RED. The DCI Notice contains two response forms which are to be completed and submitted to the Agency within 90 days of receipt. The first form, " Data Call In Response," asks whether the registrant will meet the data requirements for each product. The second form, " Requirements Status and Registrant's Response," lists the product specific data required for each product, including the standard six acute toxicity tests. A registrant who wishes to participate in a batch must decide whether he/ she will provide the data or depend on someone else to do so. If a registrant supplies the data to support a batch of products, he/ she must select one of the following options: Developing Data ( Option 1), Submitting an Existing Study ( Option 4), Upgrading an Existing Study ( Option 5) or Citing an Existing Study ( Option 6). If a registrant depends on another's data, he/ she must choose among: Cost Sharing ( Option 2), Offers to Cost Share ( Option 3) or Citing an Existing Study ( Option 6). If a registrant does not want to participate in a batch, the choices are Options 1, 4, 5 or 6. However, a 92 registrant should know that choosing not to participate in a batch does not preclude other registrants in the batch from citing his/ her studies and offering to cost share ( Option 3) those studies.

Thirty eight products were found which contain Imazapyr as the active ingredient. These products have been placed eight batches and a no batch group in accordance with the active and inert ingredients and type of formulation.

Batching Instructions:

No Batch: Each product in this Batch should generate their own data.

NOTE: The technical acute toxicity values included in this document are for informational purposes only. The data supporting these values may or may not meet the current acceptance criteria.

Batch 1 EPA Reg. No. Percent Active Ingredient 241 286 95.0 11603 42 95.0 Batch 2 EPA Reg. No. Percent Active Ingredient 241 387 75.0 241 402 75.0 Batch 3 EPA Reg. No. Percent Active Ingredient 228 480 53.1 241 299 53.1 241 401 53.1 34704 908 53.1 61202 1 53.1 Batch 4 EPA Reg. No. Percent Active Ingredient 241 346 28.7 241 426 28.7 34704 896 28.7 93 Batch 5 EPA Reg. No. Percent Active Ingredient 241 273 27.6 241 296 27.6 241 336 27.6 241 398 27.6 34704 905 27.6 Batch 6 EPA Reg. No. Percent Active Ingredient 241 308 5.0 34913 24 5.0 Batch 7 EPA Reg. No. Percent Active Ingredient 228 307 0.5 241 295 0.5 34913 23 0.5 Batch 8 EPA Reg. No. Percent Active Ingredient 228 308 Imazapyr: 0.5 Diuron: 2.0 241 344 Imazapyr: 0.5 Diuron: 2.0 13283 19 Imazapyr: 0.5 Diuron: 2.0 34913 22 Imazapyr: 0.5 Diuron: 2.0 94 No Batch EPA Reg. No. Percent Active Ingredient 239 2622 Imazapyr: 0.080 Oxyfluorfen: 0.700 239 2657 Imazapyr: 0.080 Glyphosate: 5.000 239 2686 Imazapyr: 0.016 Glyphosate: 1.000 241 294 14.200 241 330 3.600 241 372 Imazapyr: 7.780 Diuron: 62.220 241 377 Imazapyr: 17.500 Imazethapyr: 52.500 241 384 Imazapyr: 4.000 Imazethapyr: 12.000 Benzoic Acid: 58.900 241 400 Imazapyr: 5.050 Imazethapyr: 15.150 241 414 Imazapyr: 8.360 Glyphosate: 22.130 2217 802 Imazapyr: 0.150 Acetamide: 21.450 Imazethapyr: 4.090 62719 526 Imazapyr: 2.390 Glyphosate: 31.380 95 Appendix H. LIST OF REGISTRANTS SENT THIS DATA CALL IN NOTICE 1. BASF Corporation.

2. Nufarm Americas, Inc.

3. PBI/ Gordon Corporation.

4. Agan Chemical MFG, Ltd.

5. Rainbow Technology Corporation.

7. SSI Maxim Company, Inc.

8. Vegetation Management, LLC.

9. Etigra, LLC. 96 Appendix I. LIST OF AVAILABLE RELATED DOCUMENTS AND ELECTRONICALLY AVAILABLE FORMS Pesticide Registration Forms are available at the following EPA internet site:

http:// www. epa. gov/ opprd001/ forms/.

Pesticide Registration Forms ( These forms are in PDF format and require the Acrobat reader)

Instructions:

1. Print out and complete the forms. ( Note: Form numbers that are bolded can be filled out on your computer then printed.)

2. The completed form( s) should be submitted in hardcopy in accord with the existing policy.

3. Mail the forms, along with any additional documents necessary to comply with EPA regulations covering your request, to the address below for the Document Processing Desk.

DO NOT fax or e mail any form containing ' Confidential Business Information' or ' Sensitive Information.'

If you have any problems accessing these forms, please contact Nicole Williams at ( 703) 308 5551 or by e mail at williams. nicole@ epamail. epa. gov. 97 The following Agency Pesticide Registration Forms are currently available via the Internet at the following locations:

8570 1 Application for Pesticide Registration/ Amendment http:// www. epa. gov/ opprd001/ forms/ 8570 1. pdf.

8570 4 Confidential Statement of Formula http:// www. epa. gov/ opprd001/ forms/ 8570 4. pdf.

8570 5 Notice of Supplemental Registration of Distribution of a Registered Pesticide Product http:// www. epa. gov/ opprd001/ forms/ 8570 5. pdf.

8570 17 Application for an Experimental Use Permit http:// www. epa. gov/ opprd001/ forms/ 8570 17. pdf.

8570 25 Application for/ Notification of State Registration of a Pesticide To Meet a Special Local Need http:// www. epa. gov/ opprd001/ forms/ 8570 25. pdf.

8570 27 Formulator's Exemption Statement http:// www. epa. gov/ opprd001/ forms/ 8570 27. pdf.

8570 28 Certification of Compliance with Data Gap Procedures http:// www. epa. gov/ opprd001/ forms/ 8570 28. pdf.

8570 30 Pesticide Registration Maintenance Fee Filing http:// www. epa. gov/ opprd001/ forms/ 8570 30. pdf.

8570 32 Certification of Attempt to Enter into an Agreement with other Registrants for Development of Data http:// www. epa. gov/ opprd001/ forms/ 8570 32. pdf.

8570 34 Certification with Respect to Citations of Data ( in PR Notice 98 5) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr9 8 5. pdf.

8570 35 Data Matrix ( in PR Notice 98 5) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr9 8 5. pdf.

8570 36 Summary of the Physical/ Chemical Properties ( in PR Notice 98 1) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr9 8 1. pdf.

8570 37 Self Certification Statement for the Physical/ Chemical Properties ( in PR Notice 98 1) http:// www. epa. gov/ opppmsd1/ PR_ Notices/ pr9 8 1. pdf. 98 Pesticide Registration Kit www. epa. gov/ pesticides/ registrationkit/

Dear Registrant:

For your convenience, we have assembled an online registration kit which contains the following pertinent forms and information needed to register a pesticide product with the U. S. Environmental Protection Agency's Office of Pesticide Programs ( OPP):

1. The Federal Insecticide, Fungicide, and Rodenticide Act ( FIFRA) and the Federal Food, Drug and Cosmetic Act ( FFDCA) as Amended by the Food Quality Protection Act ( FQPA) of 1996.

2. Pesticide Registration ( PR) Notices a. 83 3 Label Improvement Program Storage and Disposal Statements b. 84 1 Clarification of Label Improvement Program c. 86 5 Standard Format for Data Submitted under FIFRA d. 87 1 Label Improvement Program for Pesticides Applied through Irrigation Systems ( Chemigation) e. 87 6 Inert Ingredients in Pesticide Products Policy Statement f. 90 1 Inert Ingredients in Pesticide Products; Revised Policy Statement g. 95 2 Notifications, Non notifications, and Minor Formulation Amendments h. 98 1 Self Certification of Product Chemistry Data with Attachments ( This document is in PDF format and requires the Acrobat reader.)

Other PR Notices can be found at http:// www. epa. gov/ opppmsd1/ PR_ Notices.

3. Pesticide Product Registration Application Forms ( These forms are in PDF format and will require the Acrobat reader.)

a. EPA Form No. 8570 1, Application for Pesticide Registration/ Amendmentb. EPA Form No. 8570 4, Confidential Statement of Formula c. EPA Form No. 8570 27, Formulator's Exemption Statement d. EPA Form No. 8570 34, Certification with Respect to Citations of Data e. EPA Form No. 8570 35, Data Matrix 4. General Pesticide Information ( Some of these forms are in PDF format and will require the Acrobat reader.)

a. Registration Division Personnel Contact List Biopesticides and Pollution Prevention Division ( BPPD) Contacts Antimicrobials Division Organizational Structure/ Contact List b. 53 F. R. 15952, Pesticide Registration Procedures; Pesticide Data Requirements ( PDF format) c. 40 CFR Part 156, Labeling Requirements for Pesticides and Devices ( PDF format) d. 40 CFR Part 158, Data Requirements for Registration ( PDF format) e. 50 F. R. 48833, Disclosure of Reviews of Pesticide Data ( November 27, 1985)

Before submitting your application for registration, you may wish to consult some additional sources of information. These include:

1. The Office of Pesticide Programs' Web Site 99 2. The booklet " General Information on Applying for Registration of Pesticides in the United States", PB92 221811, available through the National Technical Information Service ( NTIS) at the following address:

National Technical Information Service ( NTIS) 5285 Port Royal Road Springfield, VA 22161 The telephone number for NTIS is ( 703) 605 6000. Please note that EPA is currently in the process of updating this booklet to reflect the changes in the registration program resulting from the passage of the FQPA and the reorganization of the Office of Pesticide Programs. We anticipate that this publication will become available during the Fall of 1998.

3. The National Pesticide Information Retrieval System ( NPIRS) of Purdue University's Center for Environmental and Regulatory Information Systems. This service does charge a fee for subscriptions and custom searches. You can contact NPIRS by telephone at ( 765) 494 6614 or through their Web site.

4. The National Pesticide Telecommunications Network ( NPTN) can provide information on active ingredients, uses, toxicology, and chemistry of pesticides. You can contact NPTN by telephone at ( 800) 858 7378 or through their Web site: ace. orst. edu/ info/ nptn.

The Agency will return a notice of receipt of an application for registration or amended registration, experimental use permit, or amendment to a petition if the applicant or petitioner encloses with his submission a stamped, self addressed postcard. The postcard must contain the following entries to be completed by OPP:

  Date of receipt   EPA identifying number   Product Manager assignment Other identifying information may be included by the applicant to link the acknowledgment of receipt to the specific application submitted. EPA will stamp the date of receipt and provide the EPA identifying File Symbol or petition number for the new submission. The identifying number should be used whenever you contact the Agency concerning an application for registration, experimental use permit, or tolerance petition.

To assist us in ensuring that all data you have submitted for the chemical are properly coded and assigned to your company, please include a list of all synonyms, common and trade names, company experimental codes, and other names which identify the chemical ( including " blind" codes used when a sample was submitted for testing by commercial or academic facilities). Please provide a CAS number if one has been assigned. 100 Documents Associated with this RED The following documents are part of the Administrative Record for this RED document and may be included in the EPA's Office of Pesticide Programs Public Docket. Copies of these documents are not available electronically, but may be obtained by contacting the person listed on the respective Chemical Status Sheet.

1. Health Effects Division and Environmental Fate and Effects Division Science Chapters, which include the complete risk assessments and supporting documents.

2. Detailed Luis Report.