[Federal Register Volume 81, Number 154 (Wednesday, August 10, 2016)]
[Rules and Regulations]
[Page 52769]
[FR Doc No: 2016-18968]

=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF HOMELAND SECURITY

Coast Guard

33 CFR Part 117

[Docket No. USCG-2016-0677]

Drawbridge Operation Regulation; Berwick Bay-Atchafalaya River,
Morgan City, LA

AGENCY: Coast Guard, DHS.

ACTION: Notice of deviation from drawbridge regulations.

-----------------------------------------------------------------------

SUMMARY: The Coast Guard has issued a temporary deviation from the
operating schedule that governs the Morgan City Railroad Bridge across
Berwick Bay at mile 17.5 of the Atchafalaya River and the Gulf
Intracoastal Waterway, Morgan City to Port Allen Alternate Route, mile
0.3 in Morgan City, St. Mary Parish, Louisiana. The deviation is
necessary to conduct maintenance on the bridge. This deviation allows
the bridge to remain temporarily closed to navigation for five hours.

DATES: This deviation is effective from 7 a.m. to noon on August 25,
2016.

ADDRESSES: The docket for this deviation, [USCG-2016-0677] is available
at http://www.regulations.gov. Type the docket number in the ``SEARCH''
box and click ``SEARCH''. Click on Open Docket Folder on the line
associated with this deviation.

FOR FURTHER INFORMATION CONTACT: If you have questions on this
temporary deviation, call or email David Frank, Bridge Administration
Branch, Coast Guard; telephone<PHONE_NUMBER>, email
<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION: The Burlington Northern Santa Fe Railway
Company requested a temporary deviation from the operating schedule of
the Morgan City Railroad Bridge across Berwick Bay at mile 17.5 of the
Atchafalaya River and the Gulf Intracoastal Waterway, Morgan City to
Port Allen Alternate Route, mile 0.3 in Morgan City, St. Mary Parish,
Louisiana. This deviation was requested to allow the bridge owner to
replace a cracked joint on the west end of the bridge. This bridge is
governed by 33 CFR 117.5.
    This deviation allows the vertical lift bridge to remain closed to
navigation from 7 a.m. to noon on Thursday, August 25, 2016. The bridge
has a vertical clearance of 4 feet above high water in the closed-to-
navigation position and 73 feet above high water in the open-to-
navigation position. Navigation on the waterway consists of tugs with
tows, oil industry related work boats and crew boats, commercial
fishing vessels and some recreational craft.
    Vessels able to pass through the bridge in the closed position may
do so at any time and should pass at the slowest safe speed. The bridge
will not be able to open for emergencies and the Morgan City-Port Allen
Landside route through Amelia, LA is the closest available alternate
route.
    The Coast Guard will also inform the users of the waterways through
our Local and Broadcast Notices to Mariners of the change in operating
schedule for the bridge.
    In accordance with 33 CFR 117.35(e), the drawbridge must return to
its regular operating schedule immediately at the end of the effective
period of this temporary deviation. This deviation from the operating
regulations is authorized under 33 CFR 117.35.

David M. Frank,
Bridge Administrator, Eighth Coast Guard District.
[FR Doc. 2016-18968 Filed 8-9-16; 8:45 am]
BILLING CODE 9110-04-P


[Federal Register Volume 81, Number 250 (Thursday, December 29, 2016)]
[Notices]
[Page 96164]
[FR Doc No: 2016-31506]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

[Summary Notice No. PE-2016-126]

Petition for Exemption; Summary of Petition Received; Yamaha
Motor Corporation

AGENCY: Federal Aviation Administration (FAA), DOT.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: This notice contains a summary of a petition seeking relief
from specified requirements of Title 14 of the Code of Federal
Regulations. The purpose of this notice is to improve the public's
awareness of, and participation in, the FAA's exemption process.
Neither publication of this notice nor the inclusion or omission of
information in the summary is intended to affect the legal status of
the petition or its final disposition.

DATES: Comments on this petition must identify the petition docket
number and must be received on or before January 18, 2017.

ADDRESSES: Send comments identified by docket number FAA-2014-0397
using any of the following methods:
     Federal eRulemaking Portal: Go to http://www.regulations.gov and follow the online instructions for sending your
comments electronically.
     Mail: Send comments to Docket Operations, M-30; U.S.
Department of Transportation (DOT), 1200 New Jersey Avenue SE., Room
W12-140, West Building Ground Floor, Washington, DC 20590-0001.
     Hand Delivery or Courier: Take comments to Docket
Operations in Room W12-140 of the West Building Ground Floor at 1200
New Jersey Avenue SE., Washington, DC, between 9 a.m. and 5 p.m.,
Monday through Friday, except Federal holidays.
     Fax: Fax comments to Docket Operations at<PHONE_NUMBER>.
    Privacy: In accordance with 5 U.S.C. 553(c), DOT solicits comments
from the public to better inform its rulemaking process. DOT posts
these comments, without edit, including any personal information the
commenter provides, to http://www.regulations.gov, as described in the
system of records notice (DOT/ALL-14 FDMS), which can be reviewed at
http://www.dot.gov/privacy.
    Docket: Background documents or comments received may be read at
http://www.regulations.gov at any time. Follow the online instructions
for accessing the docket or go to the Docket Operations in Room W12-140
of the West Building Ground Floor at 1200 New Jersey Avenue SE.,
Washington, DC, between 9 a.m. and 5 p.m., Monday through Friday,
except Federal holidays.

FOR FURTHER INFORMATION CONTACT: Dan Ngo,<PHONE_NUMBER>, 800
Independence Avenue SW., Washington, DC 20591.
    This notice is published pursuant to 14 CFR 11.85.

    Issued in Washington, DC, on December 21, 2016.
Lirio Liu,
Director, Office of Rulemaking.

Petition for Exemption

    Docket No.: FAA-2014-0397.
    Petitioner: Yamaha Motor Corporation.
    Section(s) of 14 CFR Affected: Parts 21 and 27; and Sec. Sec.
61.23(a) and (c), 61.101(e)(4) and (5), 61.113(a) and (b), 61.315(a),
91.7(a), 91.119(c), 91.121, 91.151(a)(1) and (b), 91.405(a),
91.407(a)(1), 91.409(a)(1) and (2), 91.417(a) and (b), 137.19(c);
137.19(d); 137.19(e)(2)(ii), (iii), and (v); 137.31(a); 137.31(b);
137.33(a); and 137.42.
    Description of Relief Sought: The petitioner is requesting relief
in order to operate the FAZER UAS (over 55 pounds) for agricultural
spraying under part 137, as well as for airborne data collection,
research and development, and flight crew training.

[FR Doc. 2016-31506 Filed 12-28-16; 8:45 am]
 BILLING CODE 4910-13-P


[Federal Register Volume 85, Number 45 (Friday, March 6, 2020)]
[Rules and Regulations]
[Pages 13049-13051]
[FR Doc No: 2020-04429]

=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF HOMELAND SECURITY

Coast Guard

33 CFR Part 165

[Docket Number USCG-2019-0686]
RIN 1625-AA00

Safety Zone; San Juan Harbor, San Juan, PR

AGENCY: Coast Guard, DHS.

ACTION: Temporary final rule.

-----------------------------------------------------------------------

SUMMARY: The Coast Guard is extending the duration of a temporary
safety zone for all navigable waters within an area of one half mile
around each Liquefied Gas carrier entering and departing San Juan
Harbor and a 50-yard radius around each vessel when moored at the Puma
Energy dock, Cata[ntilde]o Oil dock, or Wharf B. This safety zone is
needed to protect personnel, transiting vessels, and Liquefied Gas
carriers. Entry of vessels or persons into this zone is prohibited
unless specifically authorized by the Captain of the Port San Juan or
his designated representative.

DATES: This rule is effective without actual notice from March 6, 2020
through April 30, 2020. For the purposes of enforcement, actual notice
will be used from February 29, 2020 through March 6, 2020.

ADDRESSES: You may submit comments identified by docket number USCG-
2019-0686 using the Federal eRulemaking Portal at https://www.regulations.gov. See the ``Public Participation and Request for
Comments'' portion of the SUPPLEMENTARY INFORMATION section for further
instructions on submitting comments.

FOR FURTHER INFORMATION CONTACT: If you have questions about this
rulemaking, call or email Lieutenant Commander Pedro Mendoza, Sector
San Juan Prevention Department, Waterways Management Division, U.S.
Coast Guard; telephone<PHONE_NUMBER>, email<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION:

I. Table of Abbreviations

CFR Code of Federal Regulations
DHS Department of Homeland Security
FR Federal Register
LNG Liquefied Natural Gas
NPRM Notice of proposed rulemaking
Sec.  Section
U.S.C. United States Code

II. Background Information and Regulatory History

    The Coast Guard is issuing this temporary rule without prior notice
and opportunity to comment pursuant to authority under section 4(a) of
the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). This
provision authorizes an agency to issue a rule without prior notice and
opportunity to comment when the agency for good cause finds that those
procedures are ``impracticable, unnecessary, or contrary to the public
interest.'' Under 5 U.S.C. 553(b)(B), the Coast Guard finds that good
cause exists for issuing this temporary final rule because it continues
to be necessary to safeguard incoming, moored, and outgoing LNG
carriers within San Juan Harbor, San Juan, Puerto Rico. This rule
extends the duration of the existing temporary safety zone on navigable
waters within one half mile around each Liquefied Gas carrier entering
and departing San Juan Harbor and a 50-yard radius around each vessel
when moored. This extension is necessary while we complete the
rulemaking process for the associated NPRM,\1\ which proposes to
permanently revise the existing regulation in Sec.  165.754 to add LNG
carriers is ongoing. The first temporary rule was effective from
September 13, 2019 until 11:59 p.m. on November 15, 2019. The second
temporary rule extended the duration of the safety zone and is set to
expire at 11:59 p.m. on February 28, 2020. This action extends the
duration of the safety zone until 11:59 p.m. on April 30, 2020. This
action allows for time to complete the rulemaking process for the
associated NPRM. Therefore, it is impracticable and contrary to the
public interest for the existing temporary safety zone to lapse.
---------------------------------------------------------------------------

    \1\ See NPRM entitled, ``Safety Zone; San Juan Harbor, San Juan,
PR, which published on December 17, 2019 (84 FR 68860).
---------------------------------------------------------------------------

    Under 5 U.S.C. 553(d)(3), the Coast Guard finds that good cause
exists for making this rule effective less than 30 days after
publication in the Federal Register for the same reasons discussed
above.

III. Legal Authority and Need for Rule

    The Coast Guard is issuing this rule under authority in 46 U.S.C.
70034. Potential hazards associated with LNG carriers continues to be a
safety concern

for anyone within 50-yards of these carriers. The purpose of this rule
is to extend the current safety zone until April 30, 2020 to ensure the
safety of vessels and the navigable waters within a 50-yard radius of
LNG and LPG carriers transiting San Juan Harbor while the rulemaking
process is completed for the NPRM, which proposes to revise the safety
zone in Sec.  165.754. This temporary final rule continues to safeguard
vessels at an adjacent berthing location, Puerto Nuevo Berth B, which
supplies LNG to the Puerto Rico Electric Power Authority (PREPA) and
other industrial sectors.

IV. Discussion of the Rule

    A moving safety zone is established in the following areas: (1) The
waters around Liquefied Gas carriers entering San Juan Harbor in an
area one half mile around each vessel, beginning one mile north of the
San Juan Harbor #1 Sea Buoy, in approximate position 18-29.3N, 66-07.6W
and continuing until the vessel is moored at the Puma Energy dock,
Cata[ntilde]o Oil dock, or Wharf B in approximate position 18-25.8N,
66-06.5W. (2) The waters around Liquefied Gas carriers in a 50-yard
radius around each vessel when moored at the Puma Energy dock,
Cata[ntilde]o Oil dock, or Wharf B. (3) The waters around Liquefied Gas
carriers departing San Juan Harbor in an area one half mile around each
vessel beginning at the Puma Energy Dock, Cata[ntilde]o Oil dock, or
Wharf B in approximate position 18-25.8N, 66-06.5W when the vessel gets
underway, and continuing until the stern passes the San Juan Harbor #1
Sea Buoy, in approximate position 18-28.3N, 66-07.6W.
    No vessel or person will be permitted to enter the safety zone
without obtaining permission from the COTP or a designated
representative. If authorization to enter, transit through, anchor in,
or remain within the safety zone is granted by the COTP San Juan or a
designated representative, all persons and vessels receiving such
authorization must comply with the instructions of the COTP San Juan or
a designated representative. The Coast Guard will provide notice of the
safety zone through Local Notice to Mariners, Broadcast Notice to
Mariners via VHF-FM marine channel 16, and designated on-scene
representatives.

V. Regulatory Analyses

    We developed this rule after considering numerous statutes and
Executive orders related to rulemaking. Below we summarize our analyses
based on a number of these statutes and Executive orders, and we
discuss First Amendment rights of protestors.

A. Regulatory Planning and Review

    Executive Orders 12866 and 13563 direct agencies to assess the
costs and benefits of available regulatory alternatives and, if
regulation is necessary, to select regulatory approaches that maximize
net benefits. Executive Order 13771 directs agencies to control
regulatory costs through a budgeting process. This rule has not been
designated a ``significant regulatory action,'' under Executive Order
12866. Accordingly, this rule has not been reviewed by the Office of
Management and Budget (OMB), and pursuant to OMB guidance it is exempt
from the requirements of Executive Order 13771.
    This regulatory action determination is based on the size,
available exceptions to the enforcement of the safety zone, and notice
to mariners. The regulated area will impact small designated areas of
navigable channels within San Juan Harbor. The rule will allow vessels
to seek permission to enter, transit through, anchor in, or remain
within the safety zone. Additionally, notifications to the marine
community will be made through Local Notice to Mariners, Broadcast
Notice to Mariners via VHF-FM marine channel 16, and on-scene
representatives. The notifications will allow the public to plan
operations around the affected areas.

B. Impact on Small Entities

    The Regulatory Flexibility Act of 1980, 5 U.S.C. 601-612, as
amended, requires Federal agencies to consider the potential impact of
regulations on small entities during rulemaking. The term ``small
entities'' comprises small businesses, not-for-profit organizations
that are independently owned and operated and are not dominant in their
fields, and governmental jurisdictions with populations of less than
50,000. The Coast Guard certifies under 5 U.S.C. 605(b) that this rule
will not have a significant economic impact on a substantial number of
small entities.
    While some owners or operators of vessels intending to transit the
safety zone may be small entities, for the reasons stated in section
V.A above, this rule will not have a significant economic impact on any
vessel owner or operator.
    Under section 213(a) of the Small Business Regulatory Enforcement
Fairness Act of 1996 (Pub. L. 104-121), we want to assist small
entities in understanding this rule. If the rule would affect your
small business, organization, or governmental jurisdiction and you have
questions concerning its provisions or options for compliance, please
call or email the person listed in the FOR FURTHER INFORMATION CONTACT
section.
    Small businesses may send comments on the actions of Federal
employees who enforce, or otherwise determine compliance with, Federal
regulations to the Small Business and Agriculture Regulatory
Enforcement Ombudsman and the Regional Small Business Regulatory
Fairness Boards. The Ombudsman evaluates these actions annually and
rates each agency's responsiveness to small business. If you wish to
comment on actions by employees of the Coast Guard, call 1-888-REG-FAIR
(1-888-734-3247). The Coast Guard will not retaliate against small
entities that question or complain about this rule or any policy or
action of the Coast Guard.

C. Collection of Information

    This rule will not call for a new collection of information under
the Paperwork Reduction Act of 1995 (44 U.S.C. 3501-3520).

D. Federalism and Indian Tribal Governments

    A rule has implications for federalism under Executive Order 13132,
Federalism, if it has a substantial direct effect on the States, on the
relationship between the national government and the States, or on the
distribution of power and responsibilities among the various levels of
government. We have analyzed this rule under that Order and have
determined that it is consistent with the fundamental federalism
principles and preemption requirements described in Executive Order
13132.
    Also, this rule does not have tribal implications under Executive
Order 13175, Consultation and Coordination with Indian Tribal
Governments, because it does not have a substantial direct effect on
one or more Indian tribes, on the relationship between the Federal
Government and Indian tribes, or on the distribution of power and
responsibilities between the Federal Government and Indian tribes. If
you believe this rule has implications for federalism or Indian tribes,
please call or email the person listed in the FOR FURTHER INFORMATION
CONTACT section above.

E. Unfunded Mandates Reform Act

    The Unfunded Mandates Reform Act of 1995 (2 U.S.C. 1531-1538)
requires Federal agencies to assess the effects of their discretionary
regulatory actions. In particular, the Act addresses actions

that may result in the expenditure by a State, local, or tribal
government, in the aggregate, or by the private sector of $100,000,000
(adjusted for inflation) or more in any one year. Though this rule will
not result in such an expenditure, we do discuss the effects of this
rule elsewhere in this preamble.

F. Environment

    We have analyzed this rule under Department of Homeland Security
Directive 023-01 and Environmental Planning COMDTINST 5090.1 (series),
which guide the Coast Guard in complying with the National
Environmental Policy Act of 1969 (42 U.S.C. 4321-4370f), and have
determined that this action is one of a category of actions that do not
individually or cumulatively have a significant effect on the human
environment. This rule involves a safety zone lasting 36 days that will
prohibit entry within one half mile around each Liquefied Gas carrier
entering and departing San Juan Harbor and a 50-yard radius around each
vessel when moored. The duration of the zone is intended to protect
personnel, vessels, and the marine environment in these navigable
waters while the separate rulemaking (84 FR 68860) to modify the San
Juan Harbor, San Juan, Puerto Rico safety zone is properly proposed and
implemented. It is categorically excluded from further review under
paragraph L60(a) in Table 3-1 of U.S. Coast Guard Environmental
Planning Implementing Procedures. A Record of Environmental
Consideration supporting this determination is available in the docket
where indicated under ADDRESSES.

G. Protest Activities

    The Coast Guard respects the First Amendment rights of protesters.
Protesters are asked to call or email the person listed in the FOR
FURTHER INFORMATION CONTACT section to coordinate protest activities so
that your message can be received without jeopardizing the safety or
security of people, places or vessels.

List of Subjects in 33 CFR Part 165

    Harbors, Marine safety, Navigation (water), Reporting and
recordkeeping requirements, Security measures, Waterways.

    For the reasons discussed in the preamble, the Coast Guard amends
33 CFR part 165 as follows:

PART 165--REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS

0
1. The authority citation for part 165 continues to read as follows:

    Authority:  46 U.S.C. 70034, 70051; 33 CFR 1.05-1, 6.04-1, 6.04-
6, and 160.5; Department of Homeland Security Delegation No. 0170.1.

0
2. Add temporary Sec.  165.T07-0686 to read as follows:

Sec.  165.T07-0686   Safety Zone; San Juan Harbor, San Juan, PR.

    (a) Location. A moving safety zone is established in the following
area:
    (1) The waters around Liquefied Gas carriers entering San Juan
Harbor in an area one half mile around each vessel, beginning one mile
north of the San Juan Harbor #1 Sea Buoy, in approximate position 18-
29.3N, 66-07.6W and continuing until the vessel is moored at the Puma
Energy dock, Cata[ntilde]o Oil dock, or Wharf B in approximate position
18-25.8N, 66-06.5W. All coordinates are North American Datum 1983.
    (2) The waters around Liquefied Gas carriers in a 50-yard radius
around each vessel when moored at the Puma Energy dock, Cata[ntilde]o
Oil dock, or Wharf B.
    (3) The waters around Liquefied Gas carriers departing San Juan
Harbor in an area one half mile around each vessel beginning at the
Puma Energy Dock, Cata[ntilde]o Oil dock, or Wharf B in approximate
position 18-25.8N, 66-06.5W when the vessel gets underway, and
continuing until the stern passes the San Juan Harbor #1 Sea Buoy, in
approximate position 18-28.3N, 66-07.6W. All coordinates referenced use
datum: NAD 83.
    (b) Definition. As used in this section, the term ``designated
representative'' means a Coast Guard Patrol Commander, including a
Coast Guard coxswain, petty officer, or other officer operating a Coast
Guard vessel and a Federal, State, and local officer designated by or
assisting the Captain of the Port (COTP) San Juan in the enforcement of
the safety zone.
    (c) Regulations. (1) No person or vessel may enter, transit, or
remain in the safety zone unless authorized by the COTP San Juan,
Puerto Rico, or a designated Coast Guard commissioned, warrant, or
petty officer. Those in the safety zone must comply with all lawful
orders or directions given to them by the COTP or the designated Coast
Guard commissioned, warrant, or petty officer.
    (2) Persons desiring to transit the area of the safety zones may
contact the COTP San Juan or his designated representative to seek
permission to transit the area. If permission is granted, all persons
and vessels must comply with the instructions of the COTP or his
designated representative.
    (3) Vessels encountering emergencies, which require transit through
the moving safety zone, should contact the Coast Guard patrol craft or
Duty Officer on VHF Channel 16. In the event of an emergency, the Coast
Guard patrol craft may authorize a vessel to transit through the safety
zone with a Coast Guard designated escort.
    (4) The COTP and the Duty Officer at Sector San Juan, Puerto Rico,
can be contacted at telephone number<PHONE_NUMBER>. The Coast Guard
Patrol Commander enforcing the safety zone can be contacted on VHF-FM
channels 16 and 22A.
    (5) All persons and vessels must comply with the instructions of
on-scene patrol personnel. On-scene patrol personnel include
commissioned, warrant, or petty officers of the U.S. Coast Guard. Coast
Guard Auxiliary and local or state officials may be present to inform
vessel operators of the requirements of this section, and other
applicable laws.
    (d) Notification. The zone described in paragraphs (a)(1) through
(3) of this section will be activated upon entry of an LNG carrier into
the navigable waters of the United States in the San Juan Captain of
the Port Zone. An LNG carrier will be identifiable by the requirement
to fly the Bravo flag (red international signal flag under Pub. 102,
International Code of Signals) from the outermost halyard (above the
pilot house) where it can most easily be seen. In addition to visual
identification of an LNG carrier, Coast Guard Sector San Juan will give
notice through Mariners Broadcast Notice to Mariners for the purpose of
enforcement of the temporary safety zone.
    (e) Enforcement period. This rule is enforced from 12:01 a.m. on
February 29, 2020 through 11:59 p.m. on April 30, 2020.

    Dated: February 28, 2020.
E.P. King,
Captain, U.S. Coast Guard,
    Captain of the Port San Juan.
[FR Doc. 2020-04429 Filed 3-5-20; 8:45 am]
 BILLING CODE 9110-04-P


Review

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018;36(4):169-191.
 doi: 10.1080/10590501.2018.1537118. Epub 2019 Jan 10.
A review on machine learning methods for in silico toxicity prediction
Gabriel Idakwo[ ][1], Joseph Luttrell[ ][1], Minjun Chen[ ][2], Huixiao Hong[ ][2], Zhaoxian Zhou[ ][1], Ping Gong[ ][3], Chaoyang Zhang[ ][1]
Affiliations expand
 PMID: 30628866
 DOI: 10.1080/10590501.2018.1537118
Abstract
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have been employed in predicting the toxicity profile of chemicals. This review provides a detailed end-to-end overview of the application of machine learning algorithms to Structure-Activity Relationship (SAR)-based predictive toxicology. From raw data to model validation, the importance of data quality is stressed as it greatly affects the predictive power of derived models. Commonly overlooked challenges such as data imbalance, activity cliff, model evaluation, and definition of applicability domain are highlighted, and plausible solutions for alleviating these challenges are discussed.
Keywords: Toxicity prediction; machine learning; model reliability; molecular descriptors; prediction accuracy; structure-activity relationship.
Similar articles
 Machine learning models for predicting endocrine disruption potential of environmental chemicals.
      Chierici M, Giulini M, Bussola N, Jurman G, Furlanello C.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018;36(4):237-251. doi: 10.1080/10590501.2018.1537155. Epub 2019 Jan 10.PMID: 30628533
 Target-specific toxicity knowledgebase (TsTKb): a novel toolkit for in silico predictive toxicology.
      Li Y, Idakwo G, Thangapandian S, Chen M, Hong H, Zhang C, Gong P.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018;36(4):219-236. doi: 10.1080/10590501.2018.1537148. Epub 2018 Nov 14.PMID: 30426823
 In Silico Prediction of Chemical-Induced Hepatocellular Hypertrophy Using Molecular Descriptors.
      Ambe K, Ishihara K, Ochibe T, Ohya K, Tamura S, Inoue K, Yoshida M, Tohkin M.Toxicol Sci. 2018 Apr 1;162(2):667-675. doi: 10.1093/toxsci/kfx287.PMID: 29309657
 Deep learning for predicting toxicity of chemicals: a mini review.
      Tang W, Chen J, Wang Z, Xie H, Hong H.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018;36(4):252-271. doi: 10.1080/10590501.2018.1537563. Epub 2019 Mar 1.PMID: 30821199 Review.
 Computational prediction models for assessing endocrine disrupting potential of chemicals.
      Sakkiah S, Guo W, Pan B, Kusko R, Tong W, Hong H.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018;36(4):192-218. doi: 10.1080/10590501.2018.1537132. Epub 2019 Jan 11.PMID: 30633647 Review.
Show more similar articles See all similar articles
Cited by 3 articles
 Computational Models Using Multiple Machine Learning Algorithms for Predicting Drug Hepatotoxicity with the DILIrank Dataset.
      Ancuceanu R, Hovanet MV, Anghel AI, Furtunescu F, Neagu M, Constantin C, Dinu M.Int J Mol Sci. 2020 Mar 19;21(6):2114. doi: 10.3390/ijms21062114.PMID: 32204453 Free PMC article.
 Use of QSAR Global Models and Molecular Docking for Developing New Inhibitors of c-src Tyrosine Kinase.
      Ancuceanu R, Tamba B, Stoicescu CS, Dinu M.Int J Mol Sci. 2019 Dec 18;21(1):19. doi: 10.3390/ijms21010019.PMID: 31861445 Free PMC article.
 Nano-(Q)SAR for Cytotoxicity Prediction of Engineered Nanomaterials.
      Buglak AA, Zherdev AV, Dzantiev BB.Molecules. 2019 Dec 11;24(24):4537. doi: 10.3390/molecules24244537.PMID: 31835808 Free PMC article. Review.
Publication types
 Research Support, U.S. Gov't, Non-P.H.S.
 Review
MeSH terms
 Algorithms

 Computer Simulation

 Environmental Pollutants / toxicity*

 Machine Learning

 Quantitative Structure-Activity Relationship

 Support Vector Machine

 Toxicity Tests / methods*
Substances
 Environmental Pollutants

LinkOut - more resources
 Full Text Sources
       Taylor & Francis
 Miscellaneous
       NCI CPTAC Assay Portal


[Federal Register: May 20, 2008 (Volume 73, Number 98)]
[Notices]
[Page 29171]
[DOCID:fr20my08-78]

=======================================================================
-----------------------------------------------------------------------

SECURITIES AND EXCHANGE COMMISSION

Sunshine Act Meeting

    Notice is hereby given, pursuant to the provisions of the
Government in the Sunshine Act, Pub. L. 94-409, that the Securities and
Exchange Commission will hold a Closed Meeting on May 22, 2008 at 2
p.m.
    Commissioners, Counsel to the Commissioners, the Secretary to the
Commission, and recording secretaries will attend the Closed Meeting.
Certain staff members who have an interest in the matters also may be
present.
    The General Counsel of the Commission, or his designee, has
certified that, in his opinion, one or more of the exemptions set forth
in 5 U.S.C. 552b(c)(3) (5), (7), (9)(B), and (10) and 17 CFR
200.402(a)(3), (5), (7), 9(ii) and (10), permit consideration of the
scheduled matters at the Closed Meeting.
    Commissioner Casey, as duty officer, voted to consider the items
listed for the Closed Meeting in closed session.
    The subject matter of the Closed Meeting scheduled for May 22, 2008
will be: Formal orders of investigation; institution and settlement of
injunctive actions; institution and settlement of administrative
proceedings of an enforcement nature; resolution of litigation claims;
adjudicatory matters; and post-argument discussions.
    At times, changes in Commission priorities require alterations in
the scheduling of meeting items.
    For further information and to ascertain what, if any, matters have
been added, deleted or postponed, please contact:
    The Office of the Secretary at<PHONE_NUMBER>.

    Dated: May 15, 2008.
Nancy M. Morris.
Secretary.
[FR Doc. E8-11277 Filed 5-19-08; 8:45 am]

BILLING CODE 8010-01-P


[Federal Register Volume 81, Number 44 (Monday, March 7, 2016)]
[Proposed Rules]
[Pages 11726-11727]
[FR Doc No: 2016-04877]

-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 52

[EPA-R05-OAR-2014-0664; FRL-9943-32-Region 5]

Air Plan Approval; Illinois; Base Year Emission Inventories for
the 2008 8-Hour Ozone Standard

AGENCY: Environmental Protection Agency (EPA).

ACTION: Proposed rule.

-----------------------------------------------------------------------

SUMMARY: The Environmental Protection Agency (EPA) is proposing to
approve a State Implementation Plan (SIP) revision submitted by the
Illinois Environmental Protection Agency (IEPA) on September 3, 2014,
to address emission inventory requirements for the Illinois portions of
the Chicago-Naperville, Illinois-Indiana-Wisconsin and St. Louis,
Missouri-Illinois ozone nonattainment areas under the 2008 ozone
National Ambient Air Quality Standard. The Clean Air Act (CAA) requires
emission inventories for all ozone nonattainment areas. The emission
inventories contained in Illinois' September 3, 2014, submission meet
this CAA requirement.

DATES: Comments must be received on or before April 6, 2016.

ADDRESSES: Submit your comments, identified by Docket ID No. EPA-R05-
OAR-2014-0664 at http://www.regulations.gov or via email to
<EMAIL_ADDRESS>For comments submitted at Regulations.gov,
follow the online instructions for

submitting comments. Once submitted, comments cannot be edited or
removed from Regulations.gov. For either manner of submission, EPA may
publish any comment received to its public docket. Do not submit
electronically any information you consider to be Confidential Business
Information (CBI) or other information whose disclosure is restricted
by statute. Multimedia submissions (audio, video, etc.) must be
accompanied by a written comment. The written comment is considered the
official comment and should include discussion of all points you wish
to make. EPA will generally not consider comments or comment contents
located outside of the primary submission (i.e. on the web, cloud, or
other file sharing system). For additional submission methods, please
contact the person identified in the ``For Further Information
Contact'' section. For the full EPA public comment policy, information
about CBI or multimedia submissions, and general guidance on making
effective comments, please visit http://www2.epa.gov/dockets/commenting-epa-dockets.

FOR FURTHER INFORMATION CONTACT: Edward Doty, Air Programs Branch (AR-
18J), Environmental Protection Agency, 77 West Jackson Boulevard,
Chicago, Illinois 60604,<PHONE_NUMBER><EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION: In the Final Rules section of this Federal
Register, EPA is approving IEPA's SIP revision as a direct final rule
without prior proposal because EPA views this as a noncontroversial
submittal and anticipates no adverse comments. A detailed rationale for
the approval is set forth in the direct final rule. If no adverse
comments are received in response to this rule, no further activity is
contemplated. If EPA receives adverse comments, the direct final rule
will be withdrawn and all public comments received will be addressed in
a subsequent final rule based on this proposed rule. EPA will not
institute a second comment period. Any parties interested in commenting
on this action should do so at this time. Please note that, if EPA
receives adverse comment on an amendment, paragraph, or section of this
rule and if that provision may be severed from the remainder of the
rule, EPA may adopt as final those provisions of the rule that are not
the subject of an adverse comment. For additional information see the
direct final rule, which is located in the Rules section of this
Federal Register.

    Dated: February 22, 2016.
Robert A. Kaplan,
Acting Regional Administrator, Region 5.
[FR Doc. 2016-04877 Filed 3-4-16; 8:45 am]
BILLING CODE 6560-50-P


From:
Jones, DonnaLee<EMAIL_ADDRESS>Sent:
Thursday, October 14, 2021 11:19 AM
To:
Tosh Sagar<EMAIL_ADDRESS>Subject:
RE: Seeking Info about Coke Ovens Rulemakings

Tosh - We sent the ICR out in 2016 and received results back in 2017. We typically don't post the ICR until we do the docket for the proposed rule, although we provide it to any interested party. Attached are all the materials related to the ICR with an example cover letter.

Regards,
Donna Lee Jones, Ph.D.
Senior Technical Advisor, Metals Sector
U. S. Environmental Protection Agency
Office of Air Quality Planning and Standards
Sector Policies and Programs Division / Metals & Inorganic Chemicals Group (D243-02)
Research Triangle Park, NC  27711  Tele:<PHONE_NUMBER>  Fax<PHONE_NUMBER>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Reasonableness never fails to be appreciated."  - anon.

Pronouns - She/Her/Hers
Salutation - Dr./Ms.

<< v2-Coke 114 cover letter-03-28-16-USS.docx >>
<< Coke ICR-Enclosure 1-04-01-16P.pdf >>
<< Coke ICR-Enclosure 2-062416-UPDATE.pdf >>
<< Enclosure 3 - 8-2016-RTI.pdf >>

From: Tosh Sagar<EMAIL_ADDRESS>Sent: Thursday, October 14, 2021 11:00 AM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Hi Dr. Jones,

Sorry for sending multiple emails. I know that there is an ICR for coke ovens and was wondering if you could share it with me so that I could better understand what information the agency is collecting.

I couldn't find it on Regulations.gov, EPA's website, or OMB's website.

Thank you!
Tosh

From: Tosh Sagar
Sent: Tuesday, October 12, 2021 11:29 AM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Oh that's great! Thank you, Dr. Jones.

And yes, I have Teams. I need to circle back with folks to see who wants to attend  -  I imagine it might just be 5-6. I will confirm the potential attendees and get back to you.

From: Jones, DonnaLee<EMAIL_ADDRESS>Sent: Tuesday, October 12, 2021 11:09 AM
To: Tosh Sagar<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

H Tosh. I can get the people together. Let me ask around and see who we want to invite. How many people on your end would attend? Do you have the TEAMS app?

Donna

Regards,
Donna Lee Jones, Ph.D.
Senior Technical Advisor, Metals Sector
U. S. Environmental Protection Agency
Office of Air Quality Planning and Standards
Sector Policies and Programs Division / Metals & Inorganic Chemicals Group (D243-02)
Research Triangle Park, NC  27711  Tele:<PHONE_NUMBER>  Fax<PHONE_NUMBER>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Reasonableness never fails to be appreciated."  - anon.

Pronouns - She/Her/Hers
Salutation - Dr./Ms.

From: Tosh Sagar<EMAIL_ADDRESS>Sent: Friday, October 8, 2021 9:28 AM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Hi Dr. Jones,

If my clients wanted to meet with EPA staff working on the coke ovens rules to provide input and feedback before the proposal is finalized, would that be possible and who would we reach out to?

Have a nice weekend!
Tosh

From: Tosh Sagar
Sent: Thursday, August 12, 2021 12:22 PM
To: 'Jones, DonnaLee'<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Great thanks!

From: Jones, DonnaLee<EMAIL_ADDRESS>Sent: Thursday, August 12, 2021 12:13 PM
To: Tosh Sagar<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Glad you sent me an email today because it saved me time to find your previous one. I wanted to let you know that we have posted the coke modeling file on the rule NESHAP page. There is a mechanism for comments described in the file. See link below.

https://www.epa.gov/stationary-sources-air-pollution/coke-ovens-pushing-quenching-and-battery-stacks-national-emission

Regards,
Donna Lee Jones, Ph.D.
Senior Technical Advisor, Metals Sector
U. S. Environmental Protection Agency
Office of Air Quality Planning and Standards
Sector Policies and Programs Division / Metals & Inorganic Chemicals Group (D243-02)
Research Triangle Park, NC  27711  Tele:<PHONE_NUMBER>  Fax<PHONE_NUMBER>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Reasonableness never fails to be appreciated."  - anon.

Pronouns - She/Her/Hers
Salutation - Dr./Ms.

From: Tosh Sagar<EMAIL_ADDRESS>Sent: Thursday, August 12, 2021 11:56 AM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Thank you Dr Jones!

From: Jones, DonnaLee<EMAIL_ADDRESS>Sent: Friday, August 6, 2021 3:32 PM
To: Tosh Sagar<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Can't tell from here but likely later. But that's just my guess right now.

Regards,
Donna Lee Jones, Ph.D.
Senior Technical Advisor, Metals Sector
U. S. Environmental Protection Agency
Office of Air Quality Planning and Standards
Sector Policies and Programs Division / Metals & Inorganic Chemicals Group (D243-02)
Research Triangle Park, NC  27711  Tele:<PHONE_NUMBER>  Fax<PHONE_NUMBER>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Reasonableness never fails to be appreciated."  - anon.

Pronouns - She/Her/Hers
Salutation - Dr./Ms.

From: Tosh Sagar<EMAIL_ADDRESS>Sent: Friday, August 6, 2021 3:04 PM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Thank you Dr. Jones!

I had one follow-up question, I was hoping you could answer. EPA's spring regulatory agenda gives a date of February 2022 for the proposal. Is that still valid and is there a realistic likelihood we would see it sooner than that?

Have a nice weekend.

From: Jones, DonnaLee<EMAIL_ADDRESS>Sent: Friday, August 6, 2021 2:30 PM
To: Tosh Sagar<EMAIL_ADDRESS>Subject: RE: Seeking Info about Coke Ovens Rulemakings

Mr. Sagar/Tosh - No date currently for proposal. At this time, we plan to do both reviews in same notice.

No specific issues where we need feedback right now. We follow the requirements in the Clean Air Act for these reviews. If you know of a new technology or practice for reducing emissions, that would be useful. We would need the estimated emission reductions and costs of the practice (capital costs and operating and maintenance costs) for any control measures, practices, or technology.

If you want to comment on the model file, we just posted it today. See link below:
https://www.epa.gov/stationary-sources-air-pollution/coke-ovens-pushing-quenching-and-battery-stacks-national-emission

Instructions for how to make comments are in the file.

Thanks for your interest in this rule.

Donna (or Dr. Jones)

Regards,
Donna Lee Jones, Ph.D.
Senior Technical Advisor, Metals Sector
U. S. Environmental Protection Agency
Office of Air Quality Planning and Standards
Sector Policies and Programs Division / Metals & Inorganic Chemicals Group (D243-02)
Research Triangle Park, NC  27711  Tele:<PHONE_NUMBER>  Fax<PHONE_NUMBER>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Reasonableness never fails to be appreciated."  - anon.

Pronouns - She/Her/Hers
Salutation - Dr./Ms.

From: Tosh Sagar<EMAIL_ADDRESS>Sent: Thursday, August 5, 2021 2:59 PM
To: Jones, DonnaLee<EMAIL_ADDRESS>Subject: Seeking Info about Coke Ovens Rulemakings

Hi Ms. Dr. Jones,

I wanted to reach out to see if you could share any information re: the Section 112 Reviews for both coke oven source categories.

I am hoping to learn more about the likely timeframe for the proposed rule, so that we can plan for our comments. I also wanted to check whether the two reviews would be combined in a single action or otherwise be contemporaneous (which would help simplify our comments).

I think we would also welcome an opportunity to learn if there are any issues where comments from affected communities or scientists would be particularly useful to EPA.

If you have a few minutes to chat, please let me know. Cheers,
Tosh


[Federal Register Volume 76, Number 173 (Wednesday, September 7, 2011)]
[Notices]
[Pages 55428-55429]
[FR Doc No: 2011-22901]

-----------------------------------------------------------------------

SECURITIES AND EXCHANGE COMMISSION

Sunshine Act Meeting

    Notice is hereby given, pursuant to the provisions of the
Government in the Sunshine Act, Public Law 94-409, that the Securities
and Exchange Commission will hold a Closed Meeting on Thursday,
September 8, 2011 at 2 p.m.
    Commissioners, Counsel to the Commissioners, the Secretary to the
Commission, and recording secretaries will attend the Closed Meeting.
Certain staff members who have an interest in the matters also may be
present.
    The General Counsel of the Commission, or his designee, has
certified that, in his opinion, one or more of the exemptions set forth
in 5 U.S.C. 552b(c)(3), (5), (7), 9(B) and (10) and 17 CFR
200.402(a)(3), (5), (7), 9(ii) and (10), permit consideration of the
scheduled matters at the Closed Meeting.

    Commissioner Aguilar, as duty officer, voted to consider the items
listed for the Closed Meeting in a closed session.
    The subject matter of the Closed Meeting scheduled for Thursday,
September 9, 2011 will be:
    Institution and settlement of injunctive actions;
    Institution and settlement of administrative proceedings; and
    Other matters relating to enforcement proceedings.
    At times, changes in Commission priorities require alterations in
the scheduling of meeting items.
    For further information and to ascertain what, if any, matters have
been added, deleted or postponed, please contact:
    The Office of the Secretary at<PHONE_NUMBER>.

    Dated: September 1, 2011.
Elizabeth M. Murphy,
Secretary.
[FR Doc. 2011-22901 Filed 9-2-11; 11:15 am]
BILLING CODE 8011-01-P


[Federal Register Volume 83, Number 239 (Thursday, December 13, 2018)]
[Notices]
[Page 64175]
[FR Doc No: 2018-27027]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

Notice of Opportunity for Public Comment on Surplus Property
Release at the Cullman Regional-Folsom Field Airport, Vinemont, Alabama

AGENCY: Federal Aviation Administration, DOT.

ACTION: Notice of intent to rule on land release request.

-----------------------------------------------------------------------

SUMMARY: The FAA is considering a request from the Cullman Regional
Airport Board to waive the requirement that 1.23 acres of
airport property located at the Cullman Regional-Folsom Field Airport
in Vinemont, Alabama, be used for aeronautical purposes.

DATES: Comments must be received on or before January 14, 2019.

ADDRESSES: Comments on this notice may be mailed or delivered in
triplicate to the FAA to the following address: Jackson Airports
District Office Attn: Wesley E. Mittlesteadt, Program Manager, 100 West
Cross Street, Suite B, Jackson, MS 39208-2307.
    In addition, one copy of any comments submitted to the FAA must be
mailed or delivered to Cullman Regional-Folsom Field Airport, Attn: Ben
Harrison, General Manager, 231 County Road 1360, Vinemont, AL 35179.

FOR FURTHER INFORMATION CONTACT: Wesley E. Mittlesteadt, Program
Manager, Jackson Airports District Office, 100 West Cross Street, Suite
B, Jackson, MS 39208-2307,<PHONE_NUMBER>. The land release request may
be reviewed in person at this same location.

SUPPLEMENTARY INFORMATION: The FAA is reviewing a request by Cullman
Regional Airport Board to release 1.23 acres of airport
property at the Cullman Regional-Folsom Field Airport (CMD) under the
provisions of Title 49, U.S.C. Section 47107(h). The property will be
purchased by Vinemont/Providence Volunteer Fire Department for non-
aeronautical purposes. The property is adjacent to residential property
on the west quadrant of airport property just off County Road 1371. The
net proceeds from the sale of this property will be used for eligible
airport improvement projects for general aviation facilities at the
Cullman Regional-Folsom Field Airport.
    Any person may inspect the request in person at the FAA office
listed above under FOR FURTHER INFORMATION CONTACT.
    In addition, any person may, upon request, inspect the request,
notice and other documents germane to the request in person at the
Cullman Regional-Folsom Field Airport (CMD).

    Issued in Jackson, Mississippi, on December 7, 2018.
William J. Schuller,
Acting Manager, Jackson Airports District Office Southern Region.
[FR Doc. 2018-27027 Filed 12-12-18; 8:45 am]
 BILLING CODE 4910-13-P


[Federal Register Volume 81, Number 11 (Tuesday, January 19, 2016)]
[Notices]
[Page 2873]
[FR Doc No: 2016-00823]

-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2016-N-0001]

Arthritis Advisory Committee; Notice of Meeting

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice.

-----------------------------------------------------------------------

    This notice announces a forthcoming meeting of a public advisory
committee of the Food and Drug Administration (FDA). The meeting will
be open to the public.
    Name of Committee: Arthritis Advisory Committee.
    General Function of the Committee: To provide advice and
recommendations to the Agency on FDA's regulatory issues.
    Date and Time: The meeting will be held on February 9, 2016, from
7:30 a.m. to 5 p.m.
    Location: FDA White Oak Campus, 10903 New Hampshire Ave., Bldg. 31
Conference Center, the Great Room (Rm. 1503), Silver Spring, MD 20993-
0002. Answers to commonly asked questions including information
regarding special accommodations due to a disability, visitor parking,
and transportation may be accessed at: http://www.fda.gov/AdvisoryCommittees/AboutAdvisoryCommittees/ucm408555.htm.
    Contact Person: Stephanie L. Begansky, Center for Drug Evaluation
and Research, Food and Drug Administration, 10903 New Hampshire Ave.,
Bldg. 31, Rm. 2417, Silver Spring, MD 20993-0002,<PHONE_NUMBER>, FAX:
301-847-8533<EMAIL_ADDRESS>or FDA Advisory Committee Information
Line, 1-800-741-8138<PHONE_NUMBER> in the Washington, DC area). A
notice in the Federal Register about last minute modifications that
impact a previously announced advisory committee meeting cannot always
be published quickly enough to provide timely notice. Therefore, you
should always check the Agency's Web site at http://www.fda.gov/AdvisoryCommittees/default.htm and scroll down to the appropriate
advisory committee meeting link, or call the advisory committee
information line to learn about possible modifications before coming to
the meeting.
    Agenda: The committee will discuss biologics license application
(BLA) 125544, for CT-P13, a proposed biosimilar to Janssen Biotech
Inc.'s REMICADE (infliximab), submitted by Celltrion, Inc. The proposed
indications (uses) for this product are: (1) Reducing signs and
symptoms and inducing and maintaining clinical remission in adult
patients with moderately to severely active Crohn's disease who have
had an inadequate response to conventional therapy; (2) reducing the
number of draining enterocutaneous and rectovaginal fistulas and
maintaining fistula closure in adult patients with fistulizing Crohn's
disease; (3) reducing signs and symptoms and inducing and maintaining
clinical remission in pediatric patients 6 years of age and older with
moderately to severely active Crohn's disease who have had an
inadequate response to conventional therapy; (4) reducing signs and
symptoms, inducing and maintaining clinical remission and mucosal
healing, and eliminating corticosteroid use in adult patients with
moderately to severely active ulcerative colitis who have had an
inadequate response to conventional therapy; (5) reducing signs and
symptoms and inducing and maintaining clinical remission in pediatric
patients 6 years of age and older with moderately to severely active
ulcerative colitis who have had an inadequate response to conventional
therapy; \1\ (6) in combination with methotrexate, reducing signs and
symptoms, inhibiting the progression of structural damage, and
improving physical function in patients with moderately to severely
active rheumatoid arthritis; (7) reducing signs and symptoms in
patients with active ankylosing spondylitis; (8) reducing signs and
symptoms of active arthritis, inhibiting the progression of structural
damage, and improving physical function in patients with psoriatic
arthritis; and (9) treatment of adult patients with chronic severe
(i.e., extensive and/or disabling) plaque psoriasis who are candidates
for systemic therapy and when other systemic therapies are medically
less appropriate.
---------------------------------------------------------------------------

    \1\ This indication is protected by orphan drug exclusivity
expiring on September 23, 2018. See the Orphan Drug Designations and
Approvals database at http://www.accessdata.fda.gov/scripts/opdlisting/oopd/index.cfm.
---------------------------------------------------------------------------

    FDA intends to make background material available to the public no
later than 2 business days before the meeting. If FDA is unable to post
the background material on its Web site prior to the meeting, the
background material will be made publicly available at the location of
the advisory committee meeting, and the background material will be
posted on FDA's Web site after the meeting. Background material is
available at http://www.fda.gov/AdvisoryCommittees/Calendar/default.htm. Scroll down to the appropriate advisory committee meeting
link.
    Procedure: Interested persons may present data, information, or
views, orally or in writing, on issues pending before the committee.
Written submissions may be made to the contact person on or before
January 26, 2016. Oral presentations from the public will be scheduled
between approximately 1:30 p.m. and 3 p.m. Those individuals interested
in making formal oral presentations should notify the contact person
and submit a brief statement of the general nature of the evidence or
arguments they wish to present, the names and addresses of proposed
participants, and an indication of the approximate time requested to
make their presentation on or before January 25, 2016. Time allotted
for each presentation may be limited. If the number of registrants
requesting to speak is greater than can be reasonably accommodated
during the scheduled open public hearing session, FDA may conduct a
lottery to determine the speakers for the scheduled open public hearing
session. The contact person will notify interested persons regarding
their request to speak by January 15, 2016.
    Persons attending FDA's advisory committee meetings are advised
that the Agency is not responsible for providing access to electrical
outlets.
    FDA welcomes the attendance of the public at its advisory committee
meetings and will make every effort to accommodate persons with
disabilities. If you require accommodations due to a disability, please
contact Stephanie L. Begansky at least 7 days in advance of the
meeting.
    FDA is committed to the orderly conduct of its advisory committee
meetings. Please visit our Web site at http://www.fda.gov/AdvisoryCommittees/AboutAdvisoryCommittees/ucm111462.htm for procedures
on public conduct during advisory committee meetings.
    Notice of this meeting is given under the Federal Advisory
Committee Act (5 U.S.C. app. 2).

    Dated: January 11, 2016.
Jill Hartzler Warner,
Associate Commissioner for Special Medical Programs.
[FR Doc. 2016-00823 Filed 1-15-16; 8:45 am]
 BILLING CODE 4164-01-P


[Federal Register Volume 87, Number 138 (Wednesday, July 20, 2022)]
[Notices]
[Pages 43343-43346]
[FR Doc No: 2022-15445]

-----------------------------------------------------------------------

SECURITIES AND EXCHANGE COMMISSION

[Release No. 34-95280; File No. SR-Phlx-2022-29]

Self-Regulatory Organizations; Nasdaq PHLX LLC; Notice of Filing
and Immediate Effectiveness of Proposed Rule Change To Amend Phlx
Options 7, Section 4

July 14, 2022.
    Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934
(``Act''),\1\ and Rule 19b-4 thereunder,\2\ notice is hereby given that
on June 30, 2022, Nasdaq PHLX LLC (``Phlx'' or ``Exchange'') filed with
the Securities and Exchange Commission (``SEC'' or ``Commission'') the
proposed rule change as described in Items I, II, and III, below, which
Items have been prepared by the Exchange. The Commission is publishing
this notice to solicit comments on the proposed rule change from
interested persons.
---------------------------------------------------------------------------

    \1\ 15 U.S.C. 78s(b)(1).
    \2\ 17 CFR 240.19b-4.
---------------------------------------------------------------------------

I. Self-Regulatory Organization's Statement of the Terms of Substance
of the Proposed Rule Change

    The Exchange proposes to amend Phlx's Pricing Schedule at Options
7, Section 4, Multiply Listed Options Fees (Includes options overlying
equities, ETFs, ETNs and indexes which are Multiply Listed) (Excludes
SPY and broad-based index options symbols listed within Options 7,
Section 5.A).
    While the changes proposed herein are effective upon filing, the
Exchange has designated that the amendments be operative on July 1,
2022.
    The text of the proposed rule change is available on the Exchange's
website at https://listingcenter.nasdaq.com/rulebook/phlx/rules, at the
principal office of the Exchange, and at the Commission's Public
Reference Room.

II. Self-Regulatory Organization's Statement of the Purpose of, and
Statutory Basis for, the Proposed Rule Change

    In its filing with the Commission, the Exchange included statements
concerning the purpose of and basis for the proposed rule change and
discussed any comments it received on the proposed rule change. The
text of these statements may be examined at the places specified in
Item IV below. The Exchange has prepared summaries, set forth in
sections A, B, and C below, of the most significant aspects of such
statements.

A. Self-Regulatory Organization's Statement of the Purpose of, and
Statutory Basis for, the Proposed Rule Change

1. Purpose
    Phlx proposes to amend its Pricing Schedule at Options 7, Section
4, Multiply Listed Options Fees (Includes options overlying equities,
ETFs, ETNs and indexes which are Multiply Listed) (Excludes SPY and
broad-based index options symbols listed within Options 7, Section
5.A). Specifically, Phlx proposes to remove the rule text within note 1
of Options 7, Section 4 which provides a discount.
    Today, Phlx assesses the following electronic Penny Symbol Options
Transaction Charges: $0.00 per contract to Customer; \3\ $0.48 per
contract \4\ to Professionals; \5\ $0.22 per contract to Lead Market
Makers \6\ and Maker Makers; \7\ $0.48 per contract \8\ for Broker-

Dealers; \9\ and $0.48 per contract \10\ for Firms.\11\ Today, Phlx
assesses the following electronic non-Penny Symbol Options Transaction
Charges: $0.00 per contract to Customer; $0.75 per contract \12\ to
Professionals; $0.25 per contract \13\ to Lead Market Makers and Maker
Makers; $0.75 per contract \14\ for Broker-Dealers; and $0.75 per
contract \15\ for Firms.
---------------------------------------------------------------------------

    \3\ The term ``Customer'' applies to any transaction that is
identified by a member or member organization for clearing in the
Customer range at The Options Clearing Corporation (``OCC'') which
is not for the account of a broker or dealer or for the account of a
``Professional'' (as that term is defined in Options 1, Section
1(b)(45)). See Options 7, Section 1(c).
    \4\ Electronic Complex Orders will be assessed $0.40 per
contract. See note 2 within Options 7, Section 4 of the Pricing
Schedule.
    \5\ The term ``Professional'' applies to transactions for the
accounts of Professionals, as defined in Options 1, Section 1(b)(45)
means any person or entity that (i) is not a broker or dealer in
securities, and (ii) places more than 390 orders in listed options
per day on average during a calendar month for its own beneficial
account(s). See Options 7, Section 1(c).
    \6\ The term ``Lead Market Maker'' applies to transactions for
the account of a Lead Market Maker (as defined in Options 2, Section
12(a)). A Lead Market Maker is an Exchange member who is registered
as an options Lead Market Maker pursuant to Options 2, Section
12(a). An options Lead Market Maker includes a Remote Lead Market
Maker which is defined as an options Lead Market Maker in one or
more classes that does not have a physical presence on an Exchange
floor and is approved by the Exchange pursuant to Options 2, Section
11. See Options 7, Section 1(c). The term ``Floor Lead Market
Maker'' is a member who is registered as an options Lead Market
Maker pursuant to Options 2, Section 12(a) and has a physical
presence on the Exchange's trading floor. See Options 8, Section
2(a)(3).
    \7\ The term ``Market Maker'' is defined in Options 1, Section
1(b)(28) as a member of the Exchange who is registered as an options
Market Maker pursuant to Options 2, Section 12(a). A Market Maker
includes SQTs and RSQTs as well as Floor Market Makers. See Options
7, Section 1(c). The term ``Floor Market Maker'' is a Market Maker
who is neither an SQT or an RSQT. A Floor Market Maker may provide a
quote in open outcry. See Options 8, Section 2(a)(4).
    \8\ Electronic Complex Orders will be assessed $0.40 per
contract. See note 2 within Options 7, Section 4 of the Pricing
Schedule.
    \9\ The term ``Broker-Dealer'' applies to any transaction which
is not subject to any of the other transaction fees applicable
within a particular category. See Options 7, Section 1(c).
    \10\ Electronic Complex Orders will be assessed $0.40 per
contract. See note 2 within Options 7, Section 4 of the Pricing
Schedule.
    \11\ The term ``Firm'' applies to any transaction that is
identified by a member or member organization for clearing in the
Firm range at The Options Clearing Corporation. See Options 7,
Section 1(c).
    \12\ Any member or member organization under Common Ownership
with another member or member organization or an Appointed OFP of an
Affiliated Entity that qualifies for Customer Rebate Tiers 4 or 5 in
Options 7, Section 2 of the Pricing Schedule will be assessed $0.65
per contract. See note 3 within Options 7, Section 4 of the Pricing
Schedule.
    \13\ Any member or member organization under Common Ownership
with another member or member organization or an Appointed MM of an
Affiliate Entity that qualifies for Customer Rebate Tiers 4 or 5 in
Options 7, Section 2 of the Pricing Schedule will be assessed $0.23
per contract. See note 4 within Options 7, Section 4 of the Pricing
Schedule.
    \14\ Any member or member organization under Common Ownership
with another member or member organization or an Appointed OFP of an
Affiliated Entity that qualifies for Customer Rebate Tiers 4 or 5 in
Options 7, Section 2 of the Pricing Schedule will be assessed $0.65
per contract. See note 3 within Options 7, Section 4 of the Pricing
Schedule.
    \15\ Any member or member organization under Common Ownership
with another member or member organization or an Appointed OFP of an
Affiliated Entity that qualifies for Customer Rebate Tiers 4 or 5 in
Options 7, Section 2 of the Pricing Schedule will be assessed $0.65
per contract. See note 3 within Options 7, Section 4 of the Pricing
Schedule.
---------------------------------------------------------------------------

    Today, Phlx assesses an electronic Firm Penny and non-Penny Options
Transactions Charges of $0.45 per contract for simple orders in symbols
AAPL, BAC, EEM, FB, FXI, IWM, QQQ, TWTR, VXX and XLF. Phlx proposes to
remove the $0.45 per contract Options Transaction Charge for simple
orders applicable to AAPL, BAC, EEM, FB, FXI, IWM, QQQ, TWTR, VXX and
XLF and reserve note 1 of Options 7, Section 4 of the Pricing Schedule.
The Exchange notes that the symbols listed within note 1 of Options 7,
Section 4 of the Pricing Schedule are all Penny Symbols and would,
therefore, with this proposal be assessed an Options Transaction Charge
of $0.48 per contract for simple orders in symbols AAPL, BAC, EEM, FB,
FXI, IWM, QQQ, TWTR, VXX and XLF.
2. Statutory Basis
    The Exchange believes that its proposal is consistent with Section
6(b) of the Act,\16\ in general, and furthers the objectives of
Sections 6(b)(4) and 6(b)(5) of the Act,\17\ in particular, in that it
provides for the equitable allocation of reasonable dues, fees and
other charges among members and issuers and other persons using any
facility, and is not designed to permit unfair discrimination between
customers, issuers, brokers, or dealers.
---------------------------------------------------------------------------

    \16\ 15 U.S.C. 78f(b).
    \17\ 15 U.S.C. 78f(b)(4) and (5).
---------------------------------------------------------------------------

    The Commission and the courts have repeatedly expressed their
preference for competition over regulatory intervention in determining
prices, products, and services in the securities markets. In Regulation
NMS, while adopting a series of steps to improve the current market
model, the Commission highlighted the importance of market forces in
determining prices and SRO revenues and, also, recognized that current
regulation of the market system ``has been remarkably successful in
promoting market competition in its broader forms that are most
important to investors and listed companies.'' \18\
---------------------------------------------------------------------------

    \18\ Securities Exchange Act Release No. 51808 (June 9, 2005),
70 FR 37496, 37499 (June 29, 2005) (``Regulation NMS Adopting
Release'').
---------------------------------------------------------------------------

    Likewise, in NetCoalition v. Securities and Exchange Commission
\19\ (``NetCoalition'') the D.C. Circuit upheld the Commission's use of
a market-based approach in evaluating the fairness of market data fees
against a challenge claiming that Congress mandated a cost-based
approach.\20\ As the court emphasized, the Commission ``intended in
Regulation NMS that `market forces, rather than regulatory
requirements' play a role in determining the market data . . . to be
made available to investors and at what cost.'' \21\
---------------------------------------------------------------------------

    \19\ NetCoalition v. SEC, 615 F.3d 525 (D.C. Cir. 2010).
    \20\ See NetCoalition, at 534-535.
    \21\ Id. at 537.
---------------------------------------------------------------------------

    Further, ``[n]o one disputes that competition for order flow is
`fierce.' . . . As the SEC explained, `[i]n the U.S. national market
system, buyers and sellers of securities, and the broker-dealers that
act as their order-routing agents, have a wide range of choices of
where to route orders for execution'; [and] `no exchange can afford to
take its market share percentages for granted' because `no exchange
possesses a monopoly, regulatory or otherwise, in the execution of
order flow from broker dealers' . . . .'' \22\ Although the court and
the SEC were discussing the cash equities markets, the Exchange
believes that these views apply with equal force to the options
markets.
---------------------------------------------------------------------------

    \22\ Id. at 539 (quoting Securities Exchange Act Release No.
59039 (December 2, 2008), 73 FR 74770, 74782-83 (December 9, 2008)
(SR-NYSEArca-2006-21)).
---------------------------------------------------------------------------

    The Exchange believes that it is reasonable to eliminate the
electronic Firm Penny and non-Penny Options Transactions Charges of
$0.45 per contract for simple orders in symbols AAPL, BAC, EEM, FB,
FXI, IWM, QQQ, TWTR, VXX and XLF. By eliminating note 1 within Options
7, Section 4 of the Pricing Schedule, the Exchange would assess a Firm
Options Transaction Charge of $0.48 per contract in simple orders for
all Penny Symbols, which includes symbols AAPL, BAC, EEM, FB, FXI, IWM,
QQQ, TWTR, VXX and XLF. Since the aforementioned symbols are all Penny
Symbols, eliminating note 1 within Options 7, Section 4 would not cause
any Firm to be assessed the electronic non-Penny Options Transaction
Charge of $0.75 per contract for simple orders in symbols AAPL, BAC,
EEM, FB, FXI, IWM, QQQ, TWTR, VXX and XLF. While the Exchange is
removing this discount for these symbols, the Exchange believes that
its Options Transaction Charges remain competitive.
    The Exchange believes that it is equitable and not unfairly
discriminatory to eliminate the electronic Firm Penny and non-Penny
Options Transactions Charges of $0.45 per contract for simple orders in
symbols AAPL, BAC, EEM, FB, FXI, IWM, QQQ, TWTR, VXX and XLF and,
instead, assess these symbols an electronic Firm Options Transaction
Charge of $0.48 per contract for simple orders similar to other Penny
Symbols. Customers would continue to pay no electronic Penny Symbol
Options Transaction Charge. Customer liquidity benefits all market
participants by providing more trading opportunities which attracts
market makers. An increase in the activity of these market participants
(particularly in response to pricing) in turn facilitates tighter
spreads which may cause an additional corresponding increase in order
flow from other market participants. Lead Market Makers and Market
Makers would continue to pay a $0.22 per contract electronic Penny
Symbol Options Transaction Charge, which is lower than the $0.48 per
contract electronic Penny Symbol Options Transaction Charge paid by
Professionals, Broker-Dealers and Firms. Lead Market Makers and Market
Makers add value through continuous quoting and are subject to
additional

requirements and obligations unlike other market participants.\23\
Incentivizing Lead Market Makers Market Makers to provide greater
liquidity benefits all market participants through the quality of order
interaction. The Exchange believes that it is equitable and not
unfairly discriminatory to assess AAPL, BAC, EEM, FB, FXI, IWM, QQQ,
TWTR, VXX and XLF an electronic Firm Penny Options Transactions Charge
of $0.48 per contract in simple orders similar to all other Penny
Symbols. With this proposal, the electronic Firm, Professional and
Broker-Dealer Options Transaction Charge for simple orders would be the
same for all Penny Symbols.
---------------------------------------------------------------------------

    \23\ See Phlx Options 2, Section 5.
---------------------------------------------------------------------------

B. Self-Regulatory Organization's Statement on Burden on Competition

    The Exchange does not believe that the proposed rule change will
impose any burden on competition not necessary or appropriate in
furtherance of the purposes of the Act.
Inter-Market Competition
    The proposal does not impose an undue burden on inter-market
competition. The Exchange believes its proposal remains competitive
with other options markets and will offer market participants with
another choice of where to transact options. The Exchange notes that it
operates in a highly competitive market in which market participants
can readily favor competing venues if they deem fee levels at a
particular venue to be excessive, or rebate opportunities available at
other venues to be more favorable. In such an environment, the Exchange
must continually adjust its fees to remain competitive with other
exchanges. Because competitors are free to modify their own fees in
response, and because market participants may readily adjust their
order routing practices, the Exchange believes that the degree to which
fee changes in this market may impose any burden on competition is
extremely limited.
Intra-Market Competition
    The proposed amendment does not impose an undue burden on intra-
market competition. The Exchange believes that eliminating the
electronic Firm Penny and non-Penny Options Transactions Charges of
$0.45 per contract for simple orders in symbols AAPL, BAC, EEM, FB,
FXI, IWM, QQQ, TWTR, VXX and XLF and, instead, assessing these symbols
an electronic Firm Options Transaction Charge of $0.48 per contract for
simple orders, similar to other Penny Symbols, does not create an undue
burden on competition. Customers would continue to pay no electronic
Penny Symbol Options Transaction Charge. Customer liquidity benefits
all market participants by providing more trading opportunities which
attracts market makers. An increase in the activity of these market
participants (particularly in response to pricing) in turn facilitates
tighter spreads which may cause an additional corresponding increase in
order flow from other market participants. Lead Market Makers and
Market Makers would continue to pay a $0.22 per contract electronic
Penny Symbol Options Transaction Charge, which is lower than the $0.48
per contract electronic Penny Symbol Options Transaction Charge paid by
Professionals, Broker-Dealers and Firms. Lead Market Makers and Market
Makers add value through continuous quoting and are subject to
additional requirements and obligations unlike other market
participants.\24\ Incentivizing Lead Market Makers Market Makers to
provide greater liquidity benefits all market participants through the
quality of order interaction. Assessing AAPL, BAC, EEM, FB, FXI, IWM,
QQQ, TWTR, VXX and XLF an electronic Firm Penny Options Transactions
Charge of $0.48 per contract in simple orders, similar to all other
Penny Symbols, does not impose an undue burden on competition. With
this proposal, the electronic Firm, Professional and Broker-Dealer
Options Transaction Charge for simple orders would be the same for all
Penny Symbols.
---------------------------------------------------------------------------

    \24\ See Phlx Options 2, Section 5.
---------------------------------------------------------------------------

C. Self-Regulatory Organization's Statement on Comments on the Proposed
Rule Change Received From Members, Participants, or Others

    No written comments were either solicited or received.

III. Date of Effectiveness of the Proposed Rule Change and Timing for
Commission Action

    The foregoing rule change has become effective pursuant to Section
19(b)(3)(A)(ii) of the Act.\25\
---------------------------------------------------------------------------

    \25\ 15 U.S.C. 78s(b)(3)(A)(ii).
---------------------------------------------------------------------------

    At any time within 60 days of the filing of the proposed rule
change, the Commission summarily may temporarily suspend such rule
change if it appears to the Commission that such action is: (i)
necessary or appropriate in the public interest; (ii) for the
protection of investors; or (iii) otherwise in furtherance of the
purposes of the Act. If the Commission takes such action, the
Commission shall institute proceedings to determine whether the
proposed rule should be approved or disapproved.

IV. Solicitation of Comments

    Interested persons are invited to submit written data, views, and
arguments concerning the foregoing, including whether the proposed rule
change is consistent with the Act. Comments may be submitted by any of
the following methods:

Electronic Comments

     Use the Commission's internet comment form (http://www.sec.gov/rules/sro.shtml); or
     Send an email to [email protected]. Please include
File Number SR-Phlx-2022-29 on the subject line.

Paper Comments

     Send paper comments in triplicate to Secretary, Securities
and Exchange Commission, 100 F Street NE, Washington, DC 20549-1090.

All submissions should refer to File Number SR-Phlx-2022-29. This file
number should be included on the subject line if email is used. To help
the Commission process and review your comments more efficiently,
please use only one method. The Commission will post all comments on
the Commission's internet website (http://www.sec.gov/rules/sro.shtml).
    Copies of the submission, all subsequent amendments, all written
statements with respect to the proposed rule change that are filed with
the Commission, and all written communications relating to the proposed
rule change between the Commission and any person, other than those
that may be withheld from the public in accordance with the provisions
of 5 U.S.C. 552, will be available for website viewing and printing in
the Commission's Public Reference Room, 100 F Street NE, Washington, DC
20549, on official business days between the hours of 10:00 a.m. and
3:00 p.m. Copies of the filing also will be available for inspection
and copying at the principal office of the Exchange. All comments
received will be posted without change. Persons submitting comments are
cautioned that we do not redact or edit personal identifying
information from comment submissions. You should submit only
information that you wish to make available publicly.
    All submissions should refer to File Number SR-Phlx-2022-29 and
should be submitted on or before August 10, 2022.

    For the Commission, by the Division of Trading and Markets,
pursuant to delegated authority.\26\
---------------------------------------------------------------------------

    \26\ 17 CFR 200.30-3(a)(12).
---------------------------------------------------------------------------

J. Matthew DeLesDernier,
Assistant Secretary.
[FR Doc. 2022-15445 Filed 7-19-22; 8:45 am]
BILLING CODE 8011-01-P


[Federal Register Volume 82, Number 97 (Monday, May 22, 2017)]
[Notices]
[Pages 23237-23238]
[FR Doc No: 2017-10375]

-----------------------------------------------------------------------

DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Docket No. RM98-1-000]

Records Governing Off-the-Record Communications; Public Notice

    This constitutes notice, in accordance with 18 CFR 385.2201(b), of
the receipt of prohibited and exempt off-the-record communications.
    Order No. 607 (64 FR 51222, September 22, 1999) requires Commission
decisional employees, who make or receive a prohibited or exempt off-
the-record communication relevant to the merits of a contested
proceeding, to deliver to the Secretary of the Commission, a copy of
the communication, if written, or a summary of the substance of any
oral communication.
    Prohibited communications are included in a public, non-decisional
file associated with, but not a part of, the decisional record of the
proceeding. Unless the Commission determines that the prohibited
communication and any responses thereto should become a part of the
decisional record, the prohibited off-the-record communication will not
be considered by the Commission in reaching its decision. Parties to a
proceeding may seek the opportunity to respond to any facts or
contentions made in a prohibited off-the-record communication, and may
request that the Commission place the prohibited communication and
responses thereto in the decisional record. The Commission will grant
such a request only when it determines that fairness so requires. Any
person identified below as having made a prohibited off-the-record
communication shall serve the document on all parties listed on the
official service list for the applicable proceeding in accordance with
Rule 2010, 18 CFR 385.2010.
    Exempt off-the-record communications are included in the decisional
record of the proceeding, unless the communication was with a
cooperating agency as described by 40 CFR 1501.6, made under 18 CFR
385.2201(e) (1) (v).
    The following is a list of off-the-record communications recently
received by the Secretary of the Commission. The communications listed
are grouped by docket numbers in ascending order. These filings are
available for electronic review at the Commission in the Public
Reference Room or may be viewed on the Commission's Web site at http://www.ferc.gov using the eLibrary link. Enter the docket number,
excluding the last three digits, in the docket number field to access
the document. For assistance, please contact FERC Online Support at
<EMAIL_ADDRESS>or toll free at<PHONE_NUMBER>, or for TTY,
contact<PHONE_NUMBER>.

----------------------------------------------------------------------------------------------------------------
                   Docket No.                         File date                Presenter or requester
----------------------------------------------------------------------------------------------------------------
                                                   Prohibited
----------------------------------------------------------------------------------------------------------------
1. CP14-497-000.................................          5-9-2017   Irene Huhner.
----------------------------------------------------------------------------------------------------------------
                                                     Exempt
----------------------------------------------------------------------------------------------------------------
1. CP16-9-000...................................          5-3-2017  Town of Hingham, Office of the Selectmen.
2. CP15-554-000.................................          5-4-2017  U.S. House Representative Jamie Raskin.
3. P-13239-002..................................          5-9-2017  The Hobi Tribe.
4. P-1494-000...................................         5-10-2017  U.S. House Representative Jim Bridenstine.
----------------------------------------------------------------------------------------------------------------

    Dated: May 16, 2017.
Kimberly D. Bose,
Secretary.
[FR Doc. 2017-10375 Filed 5-19-17; 8:45 am]
 BILLING CODE 6717-01-P


[Federal Register Volume 86, Number 181 (Wednesday, September 22, 2021)]
[Notices]
[Pages 52672-52673]
[FR Doc No: 2021-20498]

-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-8995-01-OW]

Meeting of the National Drinking Water Advisory Council

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of a public meeting.

-----------------------------------------------------------------------

SUMMARY: The U.S. Environmental Protection Agency's (EPA) Office of
Ground Water and Drinking Water is

announcing a virtual meeting of the National Drinking Water Advisory
Council (NDWAC or Council) as authorized under the Safe Drinking Water
Act (SDWA). The purpose of the meeting is to allow members of the
NDWAC's Consumer Confidence Report Rule Revision (CCR3) Working Group
to present their preliminary recommendations to the Council on targeted
issues relating to CCR rule revisions as required under the America's
Water Infrastructure Act (AWIA) of 2018. Information about the CCR3
Working Group along with EPA's charge to the NDWAC, to provide advice
and recommendations to the agency related to revisions of the CCR rule
in the areas of accessibility challenges; advancing environmental
justice to better support underserved communities; improving
readability, understandability, clarity, and accuracy of information
and risk communication of CCRs; and CCR delivery methods may be found
on EPA's website at https://www.epa.gov/ndwac. The NDWAC will meet
again at a later date to review the Working Group's final report to the
Council and to develop advice and recommendations from the Council to
EPA.

DATES: The meeting will be held on October 12, 2021, from 10:30 a.m. to
2:30 p.m. eastern time.

ADDRESSES: This will be a virtual meeting. There will be no in-person
gathering for this meeting. For more information about attending,
providing oral statements, and accessibility for the meeting, as well
as sending written comments, see the SUPPLEMENTARY INFORMATION section
of this document.

FOR FURTHER INFORMATION CONTACT: Elizabeth Corr, NDWAC Designated
Federal Officer, Office of Ground Water and Drinking Water (Mail Code
4601), U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue
NW, Washington, DC 20460; telephone number:<PHONE_NUMBER>; email
address<EMAIL_ADDRESS>
SUPPLEMENTARY INFORMATION:
    Attending the Meeting: The meeting will be open to the general
public. The meeting agenda and information on how to register for and
attend the meeting online will be provided on EPA's website at https://www.epa.gov/ndwac prior to the meeting.
    Oral Statements: EPA will allocate 60 minutes for the public to
present oral comments during the meeting. Oral statements will be
limited to five minutes per person during the public comment period. It
is preferred that only one person present a statement on behalf of a
group or organization. Persons interested in presenting an oral
statement should send an email to<EMAIL_ADDRESS>by noon,
eastern time, on October 4, 2021. The subject line of the email should
be ``Attention Elizabeth Corr: Request to present oral comments.''
    Written Statements: Any person who wishes to file a written
statement can do so before or after the Council meeting. Send written
statements by email to<EMAIL_ADDRESS>or see the FOR FURTHER
INFORMATION CONTACT section of this document if sending statements by
mail. Written statements received by noon, eastern time, on October 5,
2021, will be shared with all members of the Council and the CCR3
Working Group prior to the meeting. Statements received after that time
for up to 30 days after the meeting will become part of the permanent
file for the meeting and will be shared with the Council and Working
Group members after conclusion of the meeting.
    Accessibility: For information on access or services for
individuals with disabilities, or to request accommodations for a
disability, please contact Elizabeth Corr by email at
<EMAIL_ADDRESS>or by phone at<PHONE_NUMBER>, preferably at
least 10 days prior to the meeting to allow as much time as possible to
process your request.
    National Drinking Water Advisory Council: The NDWAC was created by
Congress on December 16, 1974, as part of the Safe Drinking Water Act
(SDWA) of 1974, Public Law 93-523, 42 U.S.C. 300j-5, and is operated in
accordance with the provisions of the Federal Advisory Committee Act
(FACA), 5 U.S.C. App. 2. The NDWAC was established to advise, consult
with, and make recommendations to the EPA Administrator on matters
relating to activities, functions, policies, and regulations under the
SDWA. General information about the NDWAC is available at: https://www.epa.gov/ndwac.

Jennifer L. McLain,
Director, Office of Ground Water and Drinking Water.
[FR Doc. 2021-20498 Filed 9-21-21; 8:45 am]
BILLING CODE 6560-50-P


[Federal Register: October 5, 2010 (Volume 75, Number 192)]
[Notices]
[Page 61457-61458]
[DOCID:fr05oc10-49]

-----------------------------------------------------------------------

DEPARTMENT OF ENERGY

Federal Energy Regulatory Commission

[Project No. 2503-144]

Duke Energy Carolinas, LLC; Notice of Application for Amendment
of License, and Soliciting Comments, Motions To Intervene, and Protests

September 27, 2010.
    Take notice that the following hydroelectric application has been
filed with the Commission and is available for public inspection:
    a. Type of Application: Non-Capacity Amendment of License.
    b. Project No.: 2503-144.
    c. Date Filed: August 24, 2010.
    d. Applicant: Duke Energy Carolinas, LLC.
    e. Name of Project: Keowee-Toxaway Pumped-Storage Project.
    f. Location: The project is located on the Keowee, Little,
Whitewater, Toxaway, Thompson and Horsepasture Rivers, all tributaries
of the Savannah River, in Oconee and Pickens Counties, South Carolina
and in Transylvania County, North Carolina.
    g. Filed Pursuant to: Federal Power Act, 16 U.S.C. 791a-825r.
    h. Applicant Contact: Mr. Jeffery G. Lineberger, P.E., Duke Energy
Carolinas, LLC, 526 South Church Street, P.O. Box 1006, Charlotte, NC
28201,<PHONE_NUMBER><EMAIL_ADDRESS>    i. FERC Contact: Any questions regarding this notice should be
directed to Mr. Jeremy Jessup<PHONE_NUMBER> or<EMAIL_ADDRESS>    j. Deadline for filing comments, motions to intervene and protest:
October 27, 2010.

All documents may be filed electronically via the Internet. See, 18 CFR
385.2001(a)(1)(iii) and the instructions on the Commission's Web site
at http://www.ferc.gov/docs-filing/efiling.asp. If unable to be filed
electronically, documents may be paper-filed. To paper-file, an
original and seven copies should be mailed to: Secretary, Federal
Energy Regulatory Commission, 888 First Street, NE., Washington, DC
20426. Commenters can submit brief comments up to 6,000 characters,
without prior registration, using the eComment system at http://
www.ferc.gov/docs-filing/ecomment.asp. You must include your name and
contact information at the end of your comments.
    Please include the project number (P-2503-144) on any comments,
motions, or recommendations filed.
    k. Description of Request: The applicant proposes to: (1) Amend
portions of the Project's Exhibit M to reflect planned runner
replacements and related work for Units 1 and 2 of the Jocassee Pumped
Storage Development (Jocassee Development), and (2) amend the
authorized installed capacity figures in the license to reflect the
replacements and upgrades and the current Commission regulations
concerning authorized installed capacity contained in 18 CFR 11.1(i)
for both the Keowee Development and the Jocassee Development. The
runner replacement work will occur from September 2010 through May
2011. When the proposed work is completed, the revised authorized
installed capacity for the Project will be 867.6 MW, consisting of
157.5 MW for the Keowee Development

and 710.1 MW for the Jocassee Development.
    l. Locations of the Application: A copy of the application is
available for inspection and reproduction at the Commission's Public
Reference Room, located at 888 First Street, NE., Room 2A, Washington,
DC 20426, or by calling<PHONE_NUMBER>. This filing may also be viewed
on the Commission's Web site at http://www.ferc.gov/docs-filing/
efiling.asp. Enter the docket number excluding the last three digits in
the docket number field to access the document. You may also register
online at http://www.ferc.gov/docs-filing/esubscription.asp to be
notified via email of new filings and issuances related to this or
other pending projects. For assistance, call 1-866-208-3676 or e-mail
<EMAIL_ADDRESS>for TTY, call<PHONE_NUMBER>. A copy is
also available for inspection and reproduction at the address in item
(h) above.
    m. Individuals desiring to be included on the Commission's mailing
list should so indicate by writing to the Secretary of the Commission.
    n. Comments, Protests, or Motions to Intervene: Anyone may submit
comments, a protest, or a motion to intervene in accordance with the
requirements of Rules of Practice and Procedure, 18 CFR 385.210, .211,
.214. In determining the appropriate action to take, the Commission
will consider all protests or other comments filed, but only those who
file a motion to intervene in accordance with the Commission's Rules
may become a party to the proceeding. Any comments, protests, or
motions to intervene must be received on or before the specified
comment date for the particular application.
    o. Filing and Service of Responsive Documents: Any filing must (1)
Bear in all capital letters the title ``COMMENTS'', ``PROTEST'', or
``MOTION TO INTERVENE'' as applicable; (2) set forth in the heading the
name of the applicant and the project number of the application to
which the filing responds; (3) furnish the name, address, and telephone
number of the person protesting or intervening; and (4) otherwise
comply with the requirements of 18 CFR 385.2001 through 385.2005. All
comments, motions to intervene or protests must set forth their
evidentiary basis and otherwise comply with the requirements of 18 CFR
4.34(b). All comments, motions to intervene or protests should relate
to project works which are the subject of the license amendment.
Agencies may obtain copies of the application directly from the
applicant. A copy of any protest or motion to intervene must be served
upon each representative of the applicant specified in the particular
application. If an intervener files comments or documents with the
Commission relating to the merits of an issue that may affect the
responsibilities of a particular resource agency, they must also serve
a copy of the document on that resource agency. A copy of all other
filings in reference to this application must be accompanied by proof
of service on all persons listed in the service list prepared by the
Commission in this proceeding, in accordance with 18 CFR 4.34(b) and
385.2010.

Kimberly D. Bose,
Secretary.
[FR Doc. 2010-24947 Filed 10-4-10; 8:45 am]
BILLING CODE 6717-01-P


[Federal Register: February 4, 2009 (Volume 74, Number 22)]
[Notices]
[Page 6082]
[DOCID:fr04fe09-98]

-----------------------------------------------------------------------

DEPARTMENT OF TRANSPORTATION

Federal Railroad Administration

Petition for Waiver of Compliance

    In accordance with Part 211 of Title 49 Code of Federal Regulations
(CFR), notice is hereby given that the Federal Railroad Administration
(FRA) received a request for a waiver of compliance with certain
requirements of its safety standards. The individual petition is
described below, including the party seeking relief, the regulatory
provisions involved, the nature of the relief being requested, and the
petitioner's arguments in favor of relief.

BNSF Railway Company

(Waiver Petition Docket Number FRA-2008-0157)

    The BNSF Railway Company (BNSF) seeks a waiver of compliance with
the Locomotive Safety Standards, 49 CFR 229.23 (requiring a periodic
inspection at least every 92 days) and 229.25 (requiring specific tests
at every periodic inspection) for BNSF General Electric Evolution
series and Electro-Motive Diesel ACe series locomotives.
    BNSF states in their request that each of the subject locomotives
are equipped with new self-diagnostic technology and advanced computer
control, and that the locomotives were designed by the manufacturer to
be maintained at a 6 month interval. BNSF further indicates that if the
waiver is granted, the required 92 day periodic inspection will be
performed at 184 day intervals on the subject locomotives, and that
qualified mechanical forces will perform at least one of the required
daily inspections every 31 days. FRA non-complying conditions
discovered on locomotives en-route or during any daily inspection will
be moved to a mechanical facility capable of making required repairs.
    Interested parties are invited to participate in these proceedings
by submitting written views, data, or comments. FRA does not anticipate
scheduling a public hearing in connection with these proceedings since
the facts do not appear to warrant a hearing. If any interested party
desires an opportunity for oral comment, they should notify FRA, in
writing, before the end of the comment period and specify the basis for
their request.
    All communications concerning these proceedings should identify the
appropriate docket number (e.g., Waiver Petition Docket Number FRA-
2008-0157) and may be submitted by any of the following methods:
     Web site: http://www.regulations.gov. Follow the online
instructions for submitting comments.
     Fax:<PHONE_NUMBER>.
     Mail: Docket Operations Facility, U.S. Department of
Transportation, 1200 New Jersey Avenue, SE., W12-140, Washington, DC
20590.
     Hand Delivery: 1200 New Jersey Avenue, SE., Room W12-140,
Washington, DC 20590, between 9 a.m. and 5 p.m., Monday through Friday,
except Federal Holidays.
    Communications received within 45 days of the date of this notice
will be considered by FRA before final action is taken. Comments
received after that date will be considered as far as practicable. All
written communications concerning these proceedings are available for
examination during regular business hours (9 a.m.-5 p.m.) at the above
facility. All documents in the public docket are also available for
inspection and copying on the Internet at the docket facility's Web
site at http://www.regulations.gov.
    Anyone is able to search the electronic form of any written
communications and comments received into any of our dockets by the
name of the individual submitting the comment (or signing the comment,
if submitted on behalf of an association, business, labor union, etc.).
You may review DOT's complete Privacy Act Statement in the Federal
Register published on April 11, 2000 (Volume 65, Number 70; Pages
19477-78).

    Issued in Washington, DC on January 29, 2009.
Grady C. Cothen, Jr.,
Deputy Associate Administrator for Safety Standards and Program
Development.
[FR Doc. E9-2329 Filed 2-3-09; 8:45 am]

BILLING CODE 4910-06-P