UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

	OFFICE OF CHEMICAL SAFETY

	AND POLLUTION PREVENTION

MEMORANDUM

DATE:  	04/17/2013

SUBJECT:	Pyraclostrobin. Acute and Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessments to Support New Uses on Sugarcane, Persimmon, Globe Artichoke, and Belgium Endive

PC Code: 099100	DP Barcode:   410739

Decision No.: 465126;

	Registration No.: 7969-185; 7969-186; 7969-247; 7969-258; 7969- 289; 7969-291

Petition No.: 2F8038	Regulatory Action: Section 3 Registration

Risk Assessment Type: Single chemical/aggregate

	Case No.: None

TXR No.: None

	CAS No.: 175013-18-0

MRID No.:48237401	40 CFR:   180.582

FROM:		Stephen Funk, Senior Chemist

		Risk Assessment Branch III

		Health Effects Division (7509P)

THROUGH:	Nancy Dodd, Chemist

		Mohsen Sahafeyan, Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

		And

		Christine Olinger, Branch Chief

		Risk Assessment Branch III

		Health Effects Division (7509P)

TO:		Tony Kish/ Dominic Schuler, Team #22

		Fungicide Branch

		Registration Division (7505P)

		Barry O’Keefe, Risk Assessor

		Risk Assessment Branch III

		Health Effects Division (7509P)

Executive Summary

Acute and chronic dietary (food and drinking water) exposure and risk assessments were conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database (DEEM-FCID), Version 3.16.  This software uses 2003 – 2008 food consumption data from the U.S. Department of Agriculture’s  (USDA’s) National Health and Nutrition Examination Survey, What We Eat in America (NHANES/WWEIA).   The analyses were conducted in support of a human-health risk assessment for the proposed Section 3 uses of pyraclostrobin on sugar cane, persimmon, Belgium endive, and globe artichoke.  This memorandum was reviewed by two peer reviewers of the DESAC per the DESAC SOP.

The last dietary risk assessment for pyraclostrobin was performed in 2009 (DP Barcode #369379, W. Cutchin) to support a new use on alfalfa.  That assessment has been updated by new estimated per cent crop treated data from BEAD (11/08/2012), by new drinking water concentration level estimates from BEAD (02/13/2013), and by the addition of new commodities (globe artichoke, Belgium endive, persimmon).

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

A slightly refined acute dietary exposure assessment was performed for pyraclostrobin. The analysis used tolerance-level residues or highest field trial residues, 100% crop treated, and empirical or default processing factors.  Experimentally derived processing factors were used for fruit juices, tomato, sugarcane, and wheat commodities.  For all other processed commodities, DEEM default processing factors were assumed.  Estimated drinking water concentrations (EDWCs) were also used.  The estimated acute drinking water concentration for pyraclostrobin (0.0356  ppm) was calculated based on a turf scenario for surface water.

The results of the acute dietary analysis for food and drinking water indicate that acute dietary risks do not exceed the Agency’s level of concern (< 100% of the aPAD) for the U.S. population and all subgroups.  Combined dietary exposure from food and drinking water at the 95th percentile of exposure for the U.S. population is equivalent to 1.5% of the acute Population Adjusted Dose (aPAD).  The population subgroup with the highest estimated acute dietary exposure to pyraclostrobin is females 13-49 years, with an estimated exposure at the 95th percentile of 87% of the aPAD.

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization

A refined chronic dietary analysis was conducted for this assessment in order to compensate for exposure resulting from residential uses in the aggregate assessment.  The chronic dietary analysis included tolerance-level or average field trial residues, average percent crop treated estimates (2012) when available, and empirical processing factors.  Screening level estimates of agricultural uses of pyraclostrobin were provided previously by the Biological & Economic Analysis Division (BEAD).  Experimentally derived processing factors were used for fruit juices, tomato, sugar cane, and wheat commodities.  For all other processed commodities, DEEM default processing factors were assumed.  The estimated drinking water concentration for pyraclostrobin (0.0023 ppm) was calculated based on a turf scenario for surface water.

The results of the refined chronic dietary (food and drinking water) analysis are below the Agency’s level of concern for all population subgroups.  The dietary exposure for food and drinking water for the general U.S. population is 8.0% of the chronic Population Adjusted Dose (cPAD) and 27% of the cPAD for children 1-2 yrs, the population subgroup with the highest estimated chronic dietary exposure to pyraclostrobin.

Cancer Dietary Exposure Results and Characterization

The Cancer Assessment Review Committee (CARC) concluded that the pyraclostrobin is “not likely to be carcinogenic to humans.” Therefore, a cancer dietary exposure assessment was not conducted.

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects).  This dose is referred to as the population adjusted dose (PAD).  The PAD is equivalent to the point of departure (POD, NOAEL, LOAEL) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site:  “Available Information on Assessing Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link:

     HYPERLINK "http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf"  http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see SOP 99.6 (8/20/99).

The most recent dietary risk assessment for pyraclostrobin was conducted by W. Cutchin (D369379, 10/30/2009) to support a new use on alfalfa.

II.	Residue Information

Pyraclostrobin belongs to the strobilurin class of fungicides.  Strobilurins are synthetic analogs of a natural antifungal substance which inhibits spore germination, mycelial growth, and sporulation of the fungus on the leaf surface.  Pyraclostrobin tolerances have been established in 40 CFR §180.582.  Tolerances for plant commodities are listed in 40 CFR §180.582 (a)(1) for residues of the fungicide pyraclostrobin, including its metabolites and degradates.  Complinace with the tolerance levels is to be determined by measuring only the sum of pyraclostrobin  (carbamic acid, [2-[[[1-(4-chlorophenyl)-1H- pyrazol-3-yl]oxy]methyl]phenyl]methoxy-, methyl ester) and its desmethoxy metabolite, methyl 2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl carbamate, calculated as the stoichiometric equivalent of pyraclostrobin.

The HED Metabolism Assessment Review Committee (MARC memo of 10/9/01, DP# 278044, L. Cheng) determined that for purposes of tolerance and dietary risk assessments, the residues of concern in plant and rotational crop commodities include pyraclostrobin and the desmethoxy metabolite.  The residues of concern in livestock commodities include pyraclostrobin and its metabolites convertible to 1-(4-chlorophenyl)-1H-pyrazol-3-ol and 1-(4-chloro-2-hydroxyphenyl)-1H-pyrazol-3-ol.

The USDA Pesticide Data Program (PDP) monitored pesticide residues in catfish in 2008, 2009, and 2010.  Over this 3-year period, PDP analyzed 1479 samples of catfish for pyraclostrobin residues.  None of the samples contained detectable residues (lod about 0.015 ppm).  As a result, residues in fish were not included in the assessment.

The potential for secondary transfer of pyraclostrobin residues of concern in meat, milk, poultry, and eggs exists because there are several livestock feedstuffs that are associated with the existing uses.  The proposed uses do not add to the potential for transfer, as the new commodities do not include livestock feed items of regulatory interest.    A summary of the proposed and recommended tolerances for the new uses are listed in Table 1.

Table 1.  Tolerance Summary for Pyraclostrobin for New Uses

Commodity	Proposed Tolerance (ppm)	Recommended Tolerance (ppm)

Artichoke, globe	3.0	3.0

Endive, Belgium	3.0	4.0

Persimmon	3.0	3.0

Sugarcane, cane	0.2	0.2

Pyraclostrobin and the desmethoxy metabolite were determined separately in the field trial samples, and the combined residue was calculated as pyraclostrobin.

Residue Data used for Acute and Chronic Assessments:

For the acute dietary analysis, tolerance or highest average field trial residues (HAFT) and one hundred percent crop treated was assumed for all commodities.

For the refined chronic dietary analysis, average field trial residues were calculated for certain crops (coffee, sorghum grain, stone fruits crop group 12, apple, broccoli, celery, collard, grape, lettuce, citrus, pepper, mustard green,  and tomato), which are the major dietary contributors based on preliminary runs. Average field trial values were used for the new commodities persimmon, Belgium endive, sugarcane, and globe artichoke.  Field trial data were translated from the representative commodities to the non-representative commodities according to HED SOP 2000.1:”Guidance for Translation of Field Trial Data from Representative Commodities in the Crop Group Regulation to other Commodities in Each Crop Group/Subgroup.”

Residue values used for acute and chronic assessments for some of the existing and proposed uses are listed in Table 2.  For those not listed, tolerance level residues were used.

Table 2.     Residue Data used for Acute and Chronic Dietary Risk Assessments.

Commodity	Acute (Tolerance, Highest  Field Trial Residues, HR (ppm) Chronic (Average Residues, AR (ppm)

Amaranth, leafy	HR (23.38)	AR (11.77)

Arugula	HR (23.38)	AR (11.77)

Chrysanthemum	HR (23.38)	AR (11.77)

Cress, garden	HR (23.38)	AR (11.77)

Cress, upland	HR (23.38)	AR (11.77)

Dandelion, leaves	HR (23.38)	AR (11.77)

Fennel	HR (23.38)	AR (5.02)

Parsley, leaves	HR (23.38)	AR (11.77)

Radicchio	HR (23.38)	AR (0.59)

Rhubarb	HR (23.38)	AR (5.02)

Spinach	HR (23.38)	AR (11.77)

Swiss chard	HR (23.38)	AR (5.02)

Apple	Tol (1.5)	AR (0.31)

Beans, dry	HR (0.21)	Tol (0.5)

Broccoli	Tol (5.0)	AR (1.10)

Celery	HR (10.7)	AR (5.02)

Chickpea, seed	HR (0.34)	HR (0.34)

Collards	Tol (16.0)	AR (5.74)

Grape	Tol (2.0)	AR (0.768)

Guar, seed	HR (0.34)	Tol (0.5)

Lettuce, head	HR (14.4)	AR (0.59)

Lettuce, leaf	HR (20.1)	AR (7.68)

Mustard greens	Tol (16.0)	AR (5.74)

Orange	Tol (2.0)	AR (0.3)

Pea, dry	HR (0.1)	Tol (0.5)

Tomato	Tol (1.4)	AR (0.158)

Apricot 	Tol (2.5)	AR (0.602)

Cherry (sweet & sour)	Tol (2.5)	AR (0.846)

Nectarine	Tol (2.5)	AR (0.602)

Peach	Tol (2.5)	AR (0.602)

Plum 	Tol (2.5)	AR (0.198)

Coffee	Tol (0.3)	AR (0.064)

Sorghum, grain	Tol (0.6)	AR (0.09)

Artichoke, globe	Tol (3.0)	AR (0.84)

Endive, Belgium	Tol (4.0)	AR (0.82)

Persimmon	Tol (3.0)	AR (0.60)

Sugarcane, cane	Tol (0.2)	AR (0.076)

The analysis includes HED-recommended tolerance level residue values for the herb subgroup 19A, although these tolerances were never finalized. The tolerances were recommended in connection with PP# 6E7165 (D343754, J. Stokes, 02/12/2008).

Experimentally derived processing factors for several commodities were applied.  For all other processed commodities, DEEM (ver. 7.81) default processing factors were assumed. See Table 3.

Table 3.     Processing Factors for Pyraclostrobin Dietary Risk Assessment.

Commodity	PF

Apple, juice	0.2

Apple, juice - babyfood	0.2

Beet, sugar	0.4

Beet, sugar - babyfood	0.4

Beet, sugar, molasses	0.4

Beet, sugar, molasses - babyfood	0.4

Corn, field, syrup	1.5

Flaxseed, oil	1.2

Grape, juice	0.01

Grape, juice - babyfood	0.01

Grapefruit, juice	0.02

Grape - raisins	1.0

Lemon, juice	0.02

Lemon, juice-babyfood	0.02

Lime, juice	0.02

Lime, juice-babyfood	0.02

Orange, juice	0.02

Orange, juice-babyfood	0.02

Peach, dried	7.0

Plums – prunes dried	1.3

Plums - prunes dried - babyfood	1.3

Potato, dry (granules/ flakes)	6.51

Potato, dry (granules/ flakes) - babyfood	6.51

Potato, flour	6.51

Potato, flour - babyfood	6.51

Sugarcane, sugar	0.15

Sugrcane, molasses	0.15

Tangerine, juice	0.02

Tomato, paste	2.1

Tomato, puree	0.55

Wheat (Triticale), flour	0.7

Wheat (Triticale), flour - babyfood	0.7

Wheat , germ	0.85

			1Factor reduced to 1 based on use of tolerance for potato.

BEAD has provided updated percent crop treated information for pyraclostrobin (S. Haddad, 11/18/2012).  For the chronic analyses, the weighted average %CT was incorporated, which is listed as Adjustment Factor 2 in the DEEM-FCID R98 file.  One hundred percent crop treated was assumed for commodities with no % CT information.

The following average percent crop treated estimates were used in the chronic dietary risk assessments for the crops that are currently registered for pyraclostrobin:  almonds 40%; apples 15%; apricots 25%; barley 10%; green beans 5%; blueberries 45%; broccoli 5%; cabbage 10%; caneberries 50%; cantaloupes 15%; carrots 35%; cauliflower <2.5%; celery <2.5%; cherries 50%; corn 10%; cotton <2.5%; cucumber 5%; dry beans/peas 10%; garlic 15%; grapefruit 25%; grapes 30%; hazelnuts (filberts) 15%; lemons <2.5%; lettuce 5%; nectarines 10%; onions 20%; oranges 5%; peaches 20%; peanuts 25%; pears 15%; green peas 5%; pecans <2.5%; peppers 10%; pistachios 30%; plums/prunes 5%; potatoes 15%; pumpkins 20%; rice <1%; soybeans 5%; spinach 5%; squash 15%; strawberries 65%; sugar beets 45%; sugarcane 5%; sweet corn 5%; tangelos 15%; tangerines 10%; tomatoes 25%; walnuts <1%; watermelons 30%; wheat 5%.  Note that the sugarcane estimate is from a time limited Section 18 and not the proposed Section 3 registration.  Therefore, 100% crop treated was used for sugarcane.

IV Drinking Water Data

The drinking water residues used in the dietary risk assessment were provided by the Environmental Fate and Effects Division (EFED; D403871, D405066,  F. Khan, 02/13/2013, Addendum 04/04/2013) and incorporated directly into this dietary assessment.  Water residues were incorporated in the DEEM-FCID into the food categories “water, direct, all sources” and “water, indirect, all sources.”

For surface water, the estimated drinking water concentrations (EDWCs) were generated using EFED’s standard suite of models.  Pesticide Root Zone Model (PRZM v3.12.2, May 12, 2005) and Exposure Analysis Modeling System (EXAMS v<IP_ADDRESS>, Apr. 25, 2005) are simulation models coupled with the input shell PRZM/EXAMS (PE v5.0, Nov. 15, 2006) to generate EDWCs of pyraclostrobin residues that may occur in surface water for drinking water.  For ground water, Screening Concentration in Ground Water (SCI-GROW v2.3, Jul. 29, 2003) is a regression model used as a screening tool to estimate pesticide concentrations found in ground water used as drinking water.

The proposed use of pyraclostrobin in fruiting vegetables resulted in the highest surface water concentrations of at 16.6 µg/L for 1-10 year peak value from ground application and 1-10 annual year average of 1.1 µg/L from aerial application. The acute and chronic EDWCs resulting from the proposed application uses are lower than the EDWCs for surface water in the previously recommended drinking water assessments for pyraclostrobin for turf uses   ADDIN EN.CITE <EndNote><Author>Lieu</Author><Year>2010</Year><RecNum>794</RecNum ><DisplayText>(Lieu, 2010, D380018)</DisplayText><record><rec-number>794</rec-number><foreign-keys> <key app="EN" db-id="s0xer2w2o0xwx3e0a0tx0sz3zradttw529er">794</key></foreign-keys><re f-type name="EPA Document">51</ref-type><contributors><authors><author>Lieu, David</author></authors><secondary-authors><author>D280018</author></sec ondary-authors></contributors><titles><title>Tier I Drinking Water Assessment for Boscalid Used as a Seed Treatment on Rapeseed (cultivars, varieties, an/or hybrids, including canola and crambe)</title><secondary-title>September 28, 2010</secondary-title><tertiary-title>Environmental Fate and Effects Division.  Office of Pesticide Programs.  United States Environmental Protection Agency</tertiary-title></titles><keywords><keyword>boscalid</keyword></k eywords><dates><year>2010</year></dates>boscalid<urls><custom1>D380018</custom1></record></EndNote> ( HYPERLINK \l "_ENREF_7" \o "Lieu, 2010 #794" USEPA 2007 D389729+ ) . Since the EDWCs for surface water for proposed uses are lower than the previously recommended EDWCs for this chemical, the EDWCs for surface water will not supersede the EDWCs previously recommended for turf use.

Note that a proposed use on cranberries was withdrawn by IR-4 and that this withdrawn use would have resulted in a substantially higher EDWC (30X) for the annual average.  The turf use is the same evaluation provided previously by EFED and originally used in a 2007 assessment (D389729, 9/6/2007). All proposed new uses were considered.

Table 4 provides a summary of the estimated concentrations of pyraclostrobin in surface water.  In the acute analysis, the 1-in-10 year peak surface water value of 35.6 ppb was used and in the chronic analysis the surface water value of 2.3 ppb was used. Estimates of pyraclostrobin concentration in drinking water were less for groundwater sources.  The models and their descriptions are available at the EPA internet site:   HYPERLINK "http://www.epa.gov/oppefed1/models/water/"  http://www.epa.gov/oppefed1/models/water/ .

Table 4.      EDWCs of Pyraclostrobin

Crop Scenario	PRZM/EXAMS Estimated Concentrations in Surface Water (g/L)

	Acute1 (µg/L)	Chronic (µg/L)

Surface Water

NJ Nursery (no irrigation)

Turf	35.6	2.3

Groundwater2

N/A	0.02	0.02

1 These are the highest EDWCs for previously evaluated use scenarios and the estimated acute and annual average surface water concentrations were 35.6 and 2.3 µg/L respectively.  Previously estimated groundwater concentrations for acute was  0.02 µg/L 2007, D389729.

2 EDWCs based on PRZM-GW model

.

.	DEEM-FCID™ Program and Consumption Information

Pyraclostrobin acute and chronic dietary exposure assessments were conducted using the DEEM-FCID, Version 3.16, which incorporates 2003- 2008 consumption data from USDA’s NHANES/WWEIA.  The data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups.  However, for acute exposure assessment, consumption data are retained as individual consumption events.  Based on analysis of the 2003-2008 WWEIA consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50-99 years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue intake estimate.  The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD.  This procedure is performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on an individual-by-individual basis.  The reported consumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple random pairings with residue values and then summed in a probabilistic assessment.  The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis.  In accordance with HED policy, per capita exposure and risk are reported for analyses performed at all levels of refinement.  However, for deterministic assessments, any significant differences in user vs. per capita exposure and risk are specifically identified and noted in the risk assessment.

VI.	Toxicological Information

The toxicity endpoints pertinent for human risk assessment are summarized in Table 5.

Table 5. Summary of Toxicological Doses and Endpoints for Pyraclostrobin for Use in Dietary Human Health Risk Assessments.

Exposure/

Scenario	Point of Departure	Uncertainty/

FQPA Safety Factors	RfD, PAD, Level of Concern for Risk Assessment

Study and Toxicological Effects

Acute Dietary (General Population, including Infants and Children)	NOAEL = 300 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x 	Acute RfD = 3.0 mg/kg/day

aPAD = 3.0 mg/kg/day	  SEQ CHAPTER \h \r 1 Rat Acute Oral Neurotoxicity

LOAEL = 1000 mg/kg/day based on decreased body weight gain in males.

Acute Dietary

(Females 13-49 years of age)	NOAEL= 5.0 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Acute RfD = 0.05 mg/kg/day

aPAD = 0.05 mg/kg/day	Rabbit Prenatal Developmental Toxicity

LOAEL = 10.0 mg/kg/day based on developmental toxicity findings of increased resorptions.

Chronic Dietary (All Populations)	NOAEL= 3.4 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Chronic RfD = 0.034 mg/kg/day

cPAD = 0.034 mg/kg/day	  SEQ CHAPTER \h \r 1 Rat Oral Carcinogenicity

LOAEL = 9.2 mg/kg/day based on decreased body weight/body weight gain, kidney tubular casts and atrophy in both sexes; increased incidence of  liver necrosis and erosion/ulceration of the glandular- stomach and fore-stomach in males.

Cancer (oral) 	Classification:  “Not likely to be Carcinogenic to Humans” based on the absence of significant tumor increases in two adequate rodent carcinogenicity studies.

.  NOAEL = no observed adverse effect level.  LOAEL = lowest observed adverse effect level.  UF = uncertainty factor.  UFA = extrapolation from animal to human (interspecies).  UFH = potential variation in sensitivity among members of the human population (intraspecies).  UFL = use of a LOAEL to extrapolate a NOAEL.  FQPA SF = FQPA Safety Factor.  PAD = population adjusted dose (a = acute, c = chronic).  RfD = reference dose.

VII.	Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD.  The DEEM-FCID™ analyses estimate the dietary exposure of the U.S. population and various population subgroups.  The results reported in Table 6 and 7 are for the general U.S. Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50-99 years.

Results of Acute Dietary (Food and Drinking Water) Exposure Analysis

The results of the acute dietary analysis for food and drinking water indicate that acute dietary risks do not exceed the Agency’s level of concern at the 95th percentile (< 100% of the aPAD) for the U.S. population and all subgroups. At the 95th percentile, the U.S. population has an exposure from food and drinking water that results in a risk estimate for the general U.S. population of 1.5% of the aPAD.  The most highly exposed subpopulation is “females 13-49 years” at 87% of the aPAD.

Results of Chronic Dietary (Food and Drinking Water) Exposure Analysis

The results of the aggregate chronic dietary analysis for food and drinking water are below the Agency’s level of concern (<100% cPAD) for the general U.S. population (8.0% cPAD) and all population subgroups.  The most highly exposed population subgroup is children 1-2 yrs at 27% of the cPAD.  The results of the acute and chronic dietary exposure analyses are reported in Table 6 below.

Table 6.   Summary of Dietary Exposure and Risk for Pyraclostrobin Food & Drinking Water.

Population Subgroup	Acute Dietary

(95th Percentile)	Chronic Dietary	Cancer

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure

(mg/kg/day)	% cPAD	Dietary Exposure

(mg/kg/day)	Risk

General U.S. Population	0.044721	1.5	0.002707	8.0	A separate quantitative cancer risk assessment is not required.

All Infants (< 1 year old)	0.061716	2.1	0.004353	13

	Children 1-2 years old	0.083049	2.8	0.009206	27

	Children 3-5 years old	0.074666	2.5	0.006204	18

	Children 6-12 years old	0.044251	1.5	0.003525	10

	Youth 13-19 years old	0.031506	1.0	0.001832	5.4

	Adults 20-49 years old	0.041724	1.4	0.002224	6.5

	Adults 50-99 years old	0.041722	1.4	0.002252	6.6

	Females 13-49 years old	0.043481	87	0.002005	5.9

	*The subpopulations with the highest risk estimates are bolded.

Cancer Dietary Exposure Results and Characterization

As noted above, the HED CARC revisited the cancer classification for pyraclostrobin.  HED has reclassified pyraclostrobin as “not likely to be carcinogenic to humans."   Therefore, a cancer dietary exposure analysis was not conducted.

IX.	Characterization of Inputs/Outputs

In the course of conducting a refined dietary exposure analysis, decisions are made regarding the following:  the residue data used in the analysis (e.g., field trials, monitoring data, etc.), refinements incorporated in the analysis (such as percent crop treated and processing factors), and a variety of other issues which may be chemical- or crop-specific.

The acute and chronic dietary risk assessments are considered only minimally refined.

For this assessment, tolerance-level residues and field trial residue data were incorporated in the dietary analyses.  The use of field trial data in the assessment is unlikely to underestimate actual exposure because field trial data reflects conservative pesticide residues at the minimum pre-harvest interval and the maximum application rate permitted on the proposed or existing labels.  Further refinements could have been carried out with the use of field trial residue data in those instances where tolerance level residue values were utilized.

One hundred percent crop treated was assumed for the acute analysis.  The chronic assessment utilized average %CT estimates when available.  Further refinements could have been carried out if additional %CT estimates were used.

A limited number of experimentally derived processing factors were used to refine the acute and chronic analyses.  Default DEEM processing factors were incorporated for all other processed commodities.  The inclusion of additional empirical processing factors could also refine the dietary assessment.

Estimated drinking water concentrations for surface water were also incorporated. The contribution of residues in drinking water to the dietary risk is minimal.

IX.  	Conclusions

Dietary risks for pyraclostrobin are below HED’s level of concern for dietary exposure and risk.  Females 13-49 years old are the most highly exposed population subgroup for acute exposure, with risks estimates at 87% of the aPAD at the 95th percentile of exposure.  Children 1-2 years old are the most highly exposed population subgroup for chronic exposure, with risks estimates at 27% of the cPAD. Risks were lower for all other population subgroups, including the general U.S. population.  The acute and chronic dietary exposure assessments support the new uses and amendments proposed for pyraclostrobin.

X.	List of Attachments

Attachment 1.  Pyraclostrobin Acute Dietary Analysis Input File - Food & Water.

Attachment 2.  Pyraclostrobin Acute Dietary Analysis Results - Food & Water.

Attachment 3.  Pyraclostrobin Chronic Dietary Analysis Input File - Food & Water.

Attachment 4.  Pyraclostrobin Chronic Dietary Analysis Results - Food & Water.

Attachment 5.  Pyraclostrobin Screening Level Usage Analysis (SLUA).

Attachment 1.  Pyraclostrobin Acute Dietary Analysis Input File – Food & Water

Filename: C:\Documents and Settings\sfunk\My Documents\DEEMversion3.16\PyracloAcuteR08_04_15_13.R08

Chemical: Pyraclostrobin

RfD(Chronic): .034 mg/kg bw/day  NOEL(Chronic): 3.4 mg/kg bw/day

RfD(Acute): 3 mg/kg bw/day  NOEL(Acute):  300 mg/kg bw/day

Date created/last modified: 03-20-2013/08:32:53       Program ver. 3.16, 03-08-d

Comment: Food and drinking water

------------------------------------------------------------------------ -----------

   EPA     Crop                                   Def Res     Adj.Factors   Comment

   Code     Grp  Commodity Name                    (ppm)       #1    #2

---------- ---- -------------------------------  ----------  ------ ------  -------

1400003000 14   Almond                             0.040000   1.000  1.000

1400004000 14   Almond, oil                        0.040000   1.000  1.000

1400004001 14   Almond, oil-babyfood               0.040000   1.000  1.000

1400003001 14   Almond-babyfood                    0.040000   1.000  1.000

0401005000 4A   Amaranth, leafy                   23.380000   1.000  1.000

1100009000 11   Apple, dried                       1.500000   8.000  1.000

1100009001 11   Apple, dried-babyfood              1.500000   8.000  1.000

1100007000 11   Apple, fruit with peel             1.500000   1.000  1.000

1100010000 11   Apple, juice                       1.500000   0.200  1.000

1100010001 11   Apple, juice-babyfood              1.500000   0.200  1.000

1100008000 11   Apple, peeled fruit                1.500000   1.000  1.000

1100008001 11   Apple, peeled fruit-babyfood       1.500000   1.000  1.000

1100011000 11   Apple, sauce                       1.500000   1.000  1.000

1100011001 11   Apple, sauce-babyfood              1.500000   1.000  1.000

1202012000 12B  Apricot                            2.500000   1.000  1.000

1202013000 12B  Apricot, dried                     2.500000   6.000  1.000

1202014000 12B  Apricot, juice                     2.500000   1.000  1.000

1202014001 12B  Apricot, juice-babyfood            2.500000   1.000  1.000

1202012001 12B  Apricot-babyfood                   2.500000   1.000  1.000

0103015000 1CD  Arrowroot, flour                   0.040000   1.000  1.000

0103017000 1CD  Artichoke, Jerusalem               0.040000   1.000  1.000

9500016000 O    Artichoke, globe                   3.000000   1.000  1.000

0401018000 4A   Arugula                           23.380000   1.000  1.000

9500020000 O    Avocado                            0.600000   1.000  1.000

0902021000 9B   Balsam pear                        0.500000   1.000  1.000

9500023000 O    Banana                             0.040000   1.000  1.000

9500024000 O    Banana, dried                      0.040000   3.900  1.000

9500024001 O    Banana, dried-babyfood             0.040000   3.900  1.000

9500023001 O    Banana-babyfood                    0.040000   1.000  1.000

1500027000 15   Barley, bran                       1.400000   1.000  1.000

1500026000 15   Barley, flour                      1.400000   1.000  1.000

1500026001 15   Barley, flour-babyfood             1.400000   1.000  1.000

1500025000 15   Barley, pearled barley             1.400000   1.000  1.000

1500025001 15   Barley, pearled barley-babyfood    1.400000   1.000  1.000

1901029000 19A  Basil, dried leaves               85.000000   1.000  1.000

1901029001 19A  Basil, dried leaves-babyfood      85.000000   1.000  1.000

1901028000 19A  Basil, fresh leaves               25.000000   1.000  1.000

1901028001 19A  Basil, fresh leaves-babyfood      25.000000   1.000  1.000

0603035000 6C   Bean,  great northern, seed        0.210000   1.000  1.000

0603030000 6C   Bean, black, seed                  0.210000   1.000  1.000

0603032000 6C   Bean, broad, seed                  0.210000   1.000  1.000

0602031000 6B   Bean, broad, succulent             0.500000   1.000  1.000

0603034000 6C   Bean, cowpea, seed                 0.210000   1.000  1.000

0602033000 6B   Bean, cowpea, succulent            0.500000   1.000  1.000

0603036000 6C   Bean, kidney, seed                 0.210000   1.000  1.000

0603038000 6C   Bean, lima, seed                   0.210000   1.000  1.000

0602037000 6B   Bean, lima, succulent              0.500000   1.000  1.000

0603039000 6C   Bean, mung, seed                   0.210000   1.000  1.000

0603040000 6C   Bean, navy, seed                   0.210000   1.000  1.000

0603041000 6C   Bean, pink, seed                   0.210000   1.000  1.000

0603042000 6C   Bean, pinto, seed                  0.210000   1.000  1.000

0601043000 6A   Bean, snap, succulent              0.500000   1.000  1.000

0601043001 6A   Bean, snap, succulent-babyfood     0.500000   1.000  1.000

3100047000 31   Beef, fat                          0.100000   1.000  1.000

3100047001 31   Beef, fat-babyfood                 0.100000   1.000  1.000

3100048000 31   Beef, kidney                       0.200000   1.000  1.000

3100049000 31   Beef, liver                        1.500000   1.000  1.000

3100049001 31   Beef, liver-babyfood               1.500000   1.000  1.000

3100044000 31   Beef, meat                         0.100000   1.000  1.000

3100046000 31   Beef, meat byproducts              0.200000   1.000  1.000

3100046001 31   Beef, meat byproducts-babyfood     0.200000   1.000  1.000

3100045000 31   Beef, meat, dried                  0.100000   1.920  1.000

3100044001 31   Beef, meat-babyfood                0.100000   1.000  1.000

0101050000 1AB  Beet, garden, roots                0.400000   1.000  1.000

0101050001 1AB  Beet, garden, roots-babyfood       0.400000   1.000  1.000

0200051000 2    Beet, garden, tops                16.000000   1.000  1.000

0101052000 1A   Beet, sugar                        0.200000   0.400  1.000

0101053000 1A   Beet, sugar, molasses              0.200000   0.400  1.000

0101053001 1A   Beet, sugar, molasses-babyfood     0.200000   0.400  1.000

0101052001 1A   Beet, sugar-babyfood               0.200000   0.400  1.000

9500054000 O    Belgium endive                     4.000000   1.000  1.000

1301055000 13A  Blackberry                         4.000000   1.000  1.000

1301056000 13A  Blackberry, juice                  4.000000   1.000  1.000

1301056001 13A  Blackberry, juice-babyfood         4.000000   1.000  1.000

1302057000 13B  Blueberry                          4.000000   1.000  1.000

1302057001 13B  Blueberry-babyfood                 4.000000   1.000  1.000

1301058000 13A  Boysenberry                        4.000000   1.000  1.000

1400059000 14   Brazil nut                         0.040000   1.000  1.000

0501061000 5A   Broccoli                           5.000000   1.000  1.000

0502063000 5B   Broccoli raab                     16.000000   1.000  1.000

0501062000 5A   Broccoli, Chinese                  5.000000   1.000  1.000

0501061001 5A   Broccoli-babyfood                  5.000000   1.000  1.000

0501064000 5A   Brussels sprouts                   5.000000   1.000  1.000

0101067000 1AB  Burdock                            0.400000   1.000  1.000

1400068000 14   Butternut                          0.040000   1.000  1.000

0501069000 5A   Cabbage                            5.000000   1.000  1.000

0502070000 5B   Cabbage, Chinese, bok choy        16.000000   1.000  1.000

0501072000 5A   Cabbage, Chinese, mustard          5.000000   1.000  1.000

0501071000 5A   Cabbage, Chinese, napa             5.000000   1.000  1.000

9500074000 O    Canistel                           0.600000   1.000  1.000

0901075000 9A   Cantaloupe                         0.500000   1.000  1.000

0402076000 4B   Cardoon                           23.380000   1.000  1.000

0101078000 1AB  Carrot                             0.400000   1.000  1.000

0101079000 1AB  Carrot, juice                      0.400000   1.000  1.000

0101078001 1AB  Carrot-babyfood                    0.400000   1.000  1.000

1400081000 14   Cashew                             0.040000   1.000  1.000

0103082000 1CD  Cassava                            0.040000   1.000  1.000

0103082001 1CD  Cassava-babyfood                   0.040000   1.000  1.000

0501083000 5A   Cauliflower                        5.000000   1.000  1.000

0101084000 1AB  Celeriac                           0.400000   1.000  1.000

0402085000 4B   Celery                            10.700000   1.000  1.000

0402086000 4B   Celery, juice                     10.700000   1.000  1.000

0402085001 4B   Celery-babyfood                   10.700000   1.000  1.000

0402087000 4B   Celtuce                           10.700000   1.000  1.000

0902088000 9B   Chayote, fruit                     0.500000   1.000  1.000

1201090000 12A  Cherry                             2.500000   1.000  1.000

1201091000 12A  Cherry, juice                      2.500000   1.500  1.000

1201091001 12A  Cherry, juice-babyfood             2.500000   1.500  1.000

1201090001 12A  Cherry-babyfood                    2.500000   1.000  1.000

1400092000 14   Chestnut                           0.040000   1.000  1.000

4000096000 40   Chicken, fat                       0.100000   1.000  1.000

4000096001 40   Chicken, fat-babyfood              0.100000   1.000  1.000

4000094000 40   Chicken, liver                     0.100000   1.000  1.000

4000093000 40   Chicken, meat                      0.100000   1.000  1.000

4000095000 40   Chicken, meat byproducts           0.100000   1.000  1.000

4000095001 40   Chicken, meat byproducts-babyfoo   0.100000   1.000  1.000

4000093001 40   Chicken, meat-babyfood             0.100000   1.000  1.000

4000097000 40   Chicken, skin                      0.100000   1.000  1.000

4000097001 40   Chicken, skin-babyfood             0.100000   1.000  1.000

0603099000 6C   Chickpea, flour                    0.340000   1.000  1.000

0603098000 6C   Chickpea, seed                     0.340000   1.000  1.000

0603098001 6C   Chickpea, seed-babyfood            0.340000   1.000  1.000

0101100000 1AB  Chicory, roots                     0.400000   1.000  1.000

0200101000 2    Chicory, tops                     16.000000   1.000  1.000

0902102000 9B   Chinese waxgourd                   0.500000   1.000  1.000

0302103000 3B   Chive, fresh leaves               25.000000   1.000  1.000

0401104000 4A   Chrysanthemum, garland            23.380000   1.000  1.000

1901118000 19A  Cilantro, leaves                  25.000000   1.000  1.000

1901118001 19A  Cilantro, leaves-babyfood         25.000000   1.000  1.000

1001106000 10A  Citron                             2.000000   1.000  1.000

1001107000 10A  Citrus hybrids                     2.000000   1.000  1.000

1001108000 10A  Citrus, oil                        9.000000   1.000  1.000

9500116000 O    Coffee, instant                    0.300000   1.000  1.000

9500115000 O    Coffee, roasted bean               0.300000   1.000  1.000

0502117000 5B   Collards                          16.000000   1.000  1.000

1500122000 15   Corn, field, bran                  0.100000   1.000  1.000

1500120000 15   Corn, field, flour                 0.100000   1.000  1.000

1500120001 15   Corn, field, flour-babyfood        0.100000   1.000  1.000

1500121000 15   Corn, field, meal                  0.100000   1.000  1.000

1500121001 15   Corn, field, meal-babyfood         0.100000   1.000  1.000

1500125000 15   Corn, field, oil                   0.200000   1.000  1.000

1500125001 15   Corn, field, oil-babyfood          0.200000   1.000  1.000

1500123000 15   Corn, field, starch                0.100000   1.000  1.000

1500123001 15   Corn, field, starch-babyfood       0.100000   1.000  1.000

1500124000 15   Corn, field, syrup                 0.100000   1.500  1.000

1500124001 15   Corn, field, syrup-babyfood        0.100000   1.500  1.000

1500126000 15   Corn, pop                          0.100000   1.000  1.000

1500127000 15   Corn, sweet                        0.040000   1.000  1.000

1500127001 15   Corn, sweet-babyfood               0.040000   1.000  1.000

2003128000 20C  Cottonseed, oil                    0.300000   1.000  1.000

2003128001 20C  Cottonseed, oil-babyfood           0.300000   1.000  1.000

1100129000 11   Crabapple                          1.500000   1.000  1.000

0401133000 4A   Cress, garden                     23.380000   1.000  1.000

0401134000 4A   Cress, upland                     23.380000   1.000  1.000

0902135000 9B   Cucumber                           0.500000   1.000  1.000

1302136000 13B  Currant                            4.000000   1.000  1.000

1302137000 13B  Currant, dried                     4.000000   1.000  1.000

0401138000 4A   Dandelion, leaves                 23.380000   1.000  1.000

0103139000 1CD  Dasheen, corm                      0.040000   1.000  1.000

0200140000 2    Dasheen, leaves                   16.000000   1.000  1.000

1902143000 19B  Dill, seed                        25.000000   1.000  1.000

1901144000 19A  Dillweed                          25.000000   1.000  1.000

7000146000 70   Egg, white                         0.100000   1.000  1.000

7000146001 70   Egg, white (solids)-babyfood       0.100000   1.000  1.000

7000145000 70   Egg, whole                         0.100000   1.000  1.000

7000145001 70   Egg, whole-babyfood                0.100000   1.000  1.000

7000147000 70   Egg, yolk                          0.100000   1.000  1.000

7000147001 70   Egg, yolk-babyfood                 0.100000   1.000  1.000

0802148000 8BC  Eggplant                           1.400000   1.000  1.000

1302149000 13B  Elderberry                         4.000000   1.000  1.000

0401150000 4A   Endive                            23.380000   1.000  1.000

0402152000 4B   Fennel, Florence                  23.380000   1.000  1.000

2001163000 20A  Flax seed, oil                     0.450000   1.200  1.000

0301165000 3A   Garlic, bulb                       0.900000   1.000  1.000

0301165001 3A   Garlic, bulb-babyfood              0.900000   1.000  1.000

0103166000 1CD  Ginger                             0.040000   1.000  1.000

0103167000 1CD  Ginger, dried                      0.040000   1.000  1.000

0101168000 1AB  Ginseng, dried                     0.400000   1.000  1.000

3200171000 32   Goat, fat                          0.100000   1.000  1.000

3200172000 32   Goat, kidney                       0.200000   1.000  1.000

3200173000 32   Goat, liver                        1.500000   1.000  1.000

3200169000 32   Goat, meat                         0.100000   1.000  1.000

3200170000 32   Goat, meat byproducts              0.200000   1.000  1.000

1100173500 11   Goji berry                         1.500000   1.000  1.000

1302174000 13B  Gooseberry                         4.000000   1.000  1.000

1304175000 13D  Grape                              2.000000   1.000  1.000

1304176000 13D  Grape, juice                       2.000000   0.010  1.000

1304176001 13D  Grape, juice-babyfood              2.000000   0.010  1.000

9500177000 O    Grape, leaves                      2.000000   1.000  1.000

9500178000 O    Grape, raisin                      7.000000   1.000  1.000

1304179000 13D  Grape, wine and sherry             2.000000   1.000  1.000

1003180000 10C  Grapefruit                         2.000000   1.000  1.000

1003181000 10C  Grapefruit, juice                  2.000000   0.020  1.000

0603182000 6C   Guar, seed                         0.340000   1.000  1.000

0603182001 6C   Guar, seed-babyfood                0.340000   1.000  1.000

1400155000 14   Hazelnut                           0.040000   1.000  1.000

1400156000 14   Hazelnut, oil                      0.040000   1.000  1.000

1901184000 19A  Herbs, other                      25.000000   1.000  1.000

1901184001 19A  Herbs, other-babyfood             25.000000   1.000  1.000

1400185000 14   Hickory nut                        0.040000   1.000  1.000

0901187000 9A   Honeydew melon                     0.500000   1.000  1.000

9500188000 O    Hop                               23.000000   1.000  1.000

3300189000 33   Horse, meat                        0.100000   1.000  1.000

0101190000 1AB  Horseradish                        0.400000   1.000  1.000

1302191000 13B  Huckleberry                        4.000000   1.000  1.000

0502194000 5B   Kale                              16.000000   1.000  1.000

1304195000 13D  Kiwifruit, fuzzy                   4.000000   1.000  1.000

0501196000 5A   Kohlrabi                           5.000000   1.000  1.000

1002197000 10B  Kumquat                            2.000000   1.000  1.000

0302198000 3B   Leek                               0.900000   1.000  1.000

1002199000 10B  Lemon                              2.000000   1.000  1.000

1002200000 10B  Lemon, juice                       2.000000   0.020  1.000

1002200001 10B  Lemon, juice-babyfood              2.000000   0.020  1.000

1002201000 10B  Lemon, peel                        2.000000   1.000  1.000

1901202000 19A  Lemongrass                        25.000000   1.000  1.000

0603203000 6C   Lentil, seed                       0.340000   1.000  1.000

0401204000 4A   Lettuce, head                     14.400000   1.000  1.000

0401205000 4A   Lettuce, leaf                     20.100000   1.000  1.000

1002206000 10B  Lime                               2.000000   1.000  1.000

1002207000 10B  Lime, juice                        2.000000   0.020  1.000

1002207001 10B  Lime, juice-babyfood               2.000000   0.020  1.000

1301208000 13A  Loganberry                         4.000000   1.000  1.000

1100210000 11   Loquat                             1.500000   1.000  1.000

1400213000 14   Macadamia nut                      0.040000   1.000  1.000

9500215000 O    Mango                              0.600000   1.000  1.000

9500216000 O    Mango, dried                       0.600000   1.000  1.000

9500217000 O    Mango, juice                       0.600000   1.000  1.000

9500217001 O    Mango, juice-babyfood              0.600000   1.000  1.000

9500215001 O    Mango-babyfood                     0.600000   1.000  1.000

1901220000 19A  Marjoram                          25.000000   1.000  1.000

1901220001 19A  Marjoram-babyfood                 25.000000   1.000  1.000

3800221000 38   Meat, game                         0.100000   1.000  1.000

3600222000 36   Milk, fat                          0.100000   1.000  1.000

3600222001 36   Milk, fat-baby food/infant formu   0.100000   1.000  1.000

3600223000 36   Milk, nonfat solids                0.100000   1.000  1.000

3600223001 36   Milk, nonfat solids-baby food/in   0.100000   1.000  1.000

3600225001 36   Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000

3600224000 36   Milk, water                        0.100000   1.000  1.000

3600224001 36   Milk, water-babyfood/infant form   0.100000   1.000  1.000

1303227000 13C  Mulberry                           4.000000   1.000  1.000

0502229000 5B   Mustard greens                    16.000000   1.000  1.000

1202230000 12B  Nectarine                          2.500000   1.000  1.000

1500231000 15   Oat, bran                          1.200000   1.000  1.000

1500232000 15   Oat, flour                         1.200000   1.000  1.000

1500232001 15   Oat, flour-babyfood                1.200000   1.000  1.000

1500233000 15   Oat, groats/rolled oats            1.200000   1.000  1.000

1500233001 15   Oat, groats/rolled oats-babyfood   1.200000   1.000  1.000

0802234000 8BC  Okra                               1.400000   1.000  1.000

0301237000 3A   Onion, bulb                        0.900000   1.000  1.000

0301238000 3A   Onion, bulb, dried                 0.900000   9.000  1.000

0301238001 3A   Onion, bulb, dried-babyfood        0.900000   9.000  1.000

0301237001 3A   Onion, bulb-babyfood               0.900000   1.000  1.000

0302239000 3B   Onion, green                       0.900000   1.000  1.000

1001240000 10A  Orange                             2.000000   1.000  1.000

1001241000 10A  Orange, juice                      2.000000   0.020  1.000

1001241001 10A  Orange, juice-babyfood             2.000000   0.020  1.000

1001242000 10A  Orange, peel                       2.000000   1.000  1.000

9500245000 O    Papaya                             0.600000   1.000  1.000

9500246000 O    Papaya, dried                      0.600000   1.800  1.000

9500247000 O    Papaya, juice                      0.600000   1.500  1.000

9500245001 O    Papaya-babyfood                    0.600000   1.000  1.000

1901249000 19A  Parsley, dried leaves             85.000000   1.000  1.000

1901249001 19A  Parsley, dried leaves-babyfood    85.000000   1.000  1.000

0401248000 4A   Parsley, leaves                   23.380000   1.000  1.000

0101250000 1AB  Parsley, turnip rooted             0.400000   1.000  1.000

0101251000 1AB  Parsnip                            0.400000   1.000  1.000

0101251001 1AB  Parsnip-babyfood                   0.400000   1.000  1.000

0603256000 6C   Pea, dry                           0.100000   1.000  1.000

0603256001 6C   Pea, dry-babyfood                  0.100000   1.000  1.000

0601257000 6A   Pea, edible podded, succulent      0.500000   1.000  1.000

0603258000 6C   Pea, pigeon, seed                  0.100000   1.000  1.000

0602259000 6B   Pea, pigeon, succulent             0.200000   1.000  1.000

0602255000 6B   Pea, succulent                     0.200000   1.000  1.000

0602255001 6B   Pea, succulent-babyfood            0.200000   1.000  1.000

1202260000 12B  Peach                              2.500000   1.000  1.000

1202261000 12B  Peach, dried                       2.500000   7.000  1.000

1202261001 12B  Peach, dried-babyfood              2.500000   7.000  1.000

1202262000 12B  Peach, juice                       2.500000   1.000  1.000

1202262001 12B  Peach, juice-babyfood              2.500000   1.000  1.000

1202260001 12B  Peach-babyfood                     2.500000   1.000  1.000

9500263000 O    Peanut                             0.050000   1.000  1.000

9500264000 O    Peanut, butter                     0.050000   1.890  1.000

9500265000 O    Peanut, oil                        0.100000   1.000  1.000

1100266000 11   Pear                               1.500000   1.000  1.000

1100267000 11   Pear, dried                        1.500000   6.250  1.000

1100268000 11   Pear, juice                        1.500000   1.000  1.000

1100268001 11   Pear, juice-babyfood               1.500000   1.000  1.000

1100266001 11   Pear-babyfood                      1.500000   1.000  1.000

1400269000 14   Pecan                              0.040000   1.000  1.000

0802270000 8B   Pepper, bell                       1.400000   1.000  1.000

0802271000 8B   Pepper, bell, dried                1.400000   1.000  1.000

0802271001 8B   Pepper, bell, dried-babyfood       1.400000   1.000  1.000

0802270001 8B   Pepper, bell-babyfood              1.400000   1.000  1.000

0802272000 8BC  Pepper, nonbell                    1.400000   1.000  1.000

0802273000 8BC  Pepper, nonbell, dried             1.400000   1.000  1.000

0802272001 8BC  Pepper, nonbell-babyfood           1.400000   1.000  1.000

9500275000 O    Peppermint                         8.000000   1.000  1.000

9500276000 O    Peppermint, oil                    8.000000   1.000  1.000

9500277000 O    Persimmon                          3.000000   1.000  1.000

1400278000 14   Pine nut                           0.040000   1.000  1.000

1400282000 14   Pistachio                          0.700000   1.000  1.000

9500283000 O    Plantain                           0.040000   1.000  1.000

9500284000 O    Plantain, dried                    0.040000   3.900  1.000

1203285000 12C  Plum                               2.500000   1.000  1.000

1203287000 12C  Plum, prune, dried                 2.500000   1.300  1.000

1203287001 12C  Plum, prune, dried-babyfood        2.500000   1.300  1.000

1203286000 12C  Plum, prune, fresh                 2.500000   1.000  1.000

1203286001 12C  Plum, prune, fresh-babyfood        2.500000   1.000  1.000

1203288000 12C  Plum, prune, juice                 2.500000   1.400  1.000

1203288001 12C  Plum, prune, juice-babyfood        2.500000   1.400  1.000

1203285001 12C  Plum-babyfood                      2.500000   1.000  1.000

3400293000 34   Pork, fat                          0.100000   1.000  1.000

3400293001 34   Pork, fat-babyfood                 0.100000   1.000  1.000

3400294000 34   Pork, kidney                       0.200000   1.000  1.000

3400295000 34   Pork, liver                        1.500000   1.000  1.000

3400290000 34   Pork, meat                         0.100000   1.000  1.000

3400292000 34   Pork, meat byproducts              0.200000   1.000  1.000

3400292001 34   Pork, meat byproducts-babyfood     0.200000   1.000  1.000

3400290001 34   Pork, meat-babyfood                0.100000   1.000  1.000

3400291000 34   Pork, skin                         0.100000   1.000  1.000

0103296000 1C   Potato, chips                      0.040000   1.000  1.000

0103297000 1C   Potato, dry (granules/ flakes)     0.040000   1.000  1.000

0103297001 1C   Potato, dry (granules/ flakes)-b   0.040000   1.000  1.000

0103298000 1C   Potato, flour                      0.040000   1.000  1.000

0103298001 1C   Potato, flour-babyfood             0.040000   1.000  1.000

0103300000 1C   Potato, tuber, w/o peel            0.040000   1.000  1.000

0103300001 1C   Potato, tuber, w/o peel-babyfood   0.040000   1.000  1.000

0103299000 1C   Potato, tuber, w/peel              0.040000   1.000  1.000

6000304000 60   Poultry, other, fat                0.100000   1.000  1.000

6000302000 60   Poultry, other, liver              0.100000   1.000  1.000

6000301000 60   Poultry, other, meat               0.100000   1.000  1.000

6000303000 60   Poultry, other, meat byproducts    0.100000   1.000  1.000

6000305000 60   Poultry, other, skin               0.100000   1.000  1.000

1003307000 10C  Pummelo                            2.000000   1.000  1.000

0902308000 9B   Pumpkin                            0.500000   1.000  1.000

0902309000 9B   Pumpkin, seed                      0.500000   1.000  1.000

1100310000 11   Quince                             1.500000   1.000  1.000

3900312000 39   Rabbit, meat                       0.100000   1.000  1.000

0401313000 4A   Radicchio                         23.380000   1.000  1.000

0101316000 1AB  Radish, Oriental, roots            0.400000   1.000  1.000

0101314000 1AB  Radish, roots                      0.400000   1.000  1.000

0502318000 5B   Rape greens                       16.000000   1.000  1.000

2001319000 20A  Rapeseed, oil                      0.450000   1.000  1.000

2001319001 20A  Rapeseed, oil-babyfood             0.450000   1.000  1.000

1301320000 13A  Raspberry                          4.000000   1.000  1.000

1301321000 13A  Raspberry, juice                   4.000000   1.000  1.000

1301321001 13A  Raspberry, juice-babyfood          4.000000   1.000  1.000

1301320001 13A  Raspberry-babyfood                 4.000000   1.000  1.000

0402322000 4B   Rhubarb                           23.380000   1.000  1.000

0101327000 1AB  Rutabaga                           0.400000   1.000  1.000

1500328000 15   Rye, grain                         0.040000   1.000  1.000

2002330000 20B  Safflower, oil                     0.450000   1.000  1.000

2002330001 20B  Safflower, oil-babyfood            0.450000   1.000  1.000

0101331000 1AB  Salsify, roots                     0.400000   1.000  1.000

9500333000 O    Sapote, Mamey                      0.600000   1.000  1.000

1901334000 19A  Savory                            25.000000   1.000  1.000

2001337000 20A  Sesame, oil                        0.450000   1.000  1.000

2001337001 20A  Sesame, oil-babyfood               0.450000   1.000  1.000

2001336000 20A  Sesame, seed                       0.450000   1.000  1.000

2001336001 20A  Sesame, seed-babyfood              0.450000   1.000  1.000

0301338000 3A   Shallot, bulb                      0.900000   1.000  1.000

0302338500 3B   Shallot, fresh leaves              0.900000   1.000  1.000

3500341000 35   Sheep, fat                         0.100000   1.000  1.000

3500341001 35   Sheep, fat-babyfood                0.100000   1.000  1.000

3500342000 35   Sheep, kidney                      0.200000   1.000  1.000

3500343000 35   Sheep, liver                       1.500000   1.000  1.000

3500339000 35   Sheep, meat                        0.100000   1.000  1.000

3500340000 35   Sheep, meat byproducts             0.200000   1.000  1.000

3500339001 35   Sheep, meat-babyfood               0.100000   1.000  1.000

1500344000 15   Sorghum, grain                     0.600000   1.000  1.000

1500345000 15   Sorghum, syrup                     0.600000   1.000  1.000

0603348000 6C   Soybean, flour                     0.040000   1.000  1.000

0603348001 6C   Soybean, flour-babyfood            0.040000   1.000  1.000

0600350000 6    Soybean, oil                       0.040000   0.800  1.000

0600350001 6    Soybean, oil-babyfood              0.040000   0.800  1.000

0600347000 6    Soybean, seed                      0.040000   1.000  1.000

0600349000 6    Soybean, soy milk                  0.040000   1.000  1.000

0600349001 6    Soybean, soy milk-babyfood or in   0.040000   1.000  1.000

9500352000 O    Spearmint                          8.000000   1.000  1.000

9500353000 O    Spearmint, oil                     8.000000   1.000  1.000

0401355000 4A   Spinach                           23.380000   1.000  1.000

0401355001 4A   Spinach-babyfood                  23.380000   1.000  1.000

0902356000 9B   Squash, summer                     0.500000   1.000  1.000

0902356001 9B   Squash, summer-babyfood            0.500000   1.000  1.000

0902357000 9B   Squash, winter                     0.500000   1.000  1.000

0902357001 9B   Squash, winter-babyfood            0.500000   1.000  1.000

1307359000 13G  Strawberry                         4.000000   1.000  1.000

1307360000 13G  Strawberry, juice                  1.200000   1.000  1.000

1307360001 13G  Strawberry, juice-babyfood         1.200000   1.000  1.000

1307359001 13G  Strawberry-babyfood                1.200000   1.000  1.000

9500363000 O    Sugarcane, molasses                0.200000   0.150  1.000

9500363001 O    Sugarcane, molasses-babyfood       0.200000   0.150  1.000

9500362000 O    Sugarcane, sugar                   0.200000   0.150  1.000

9500362001 O    Sugarcane, sugar-babyfood          0.200000   0.150  1.000

2002365000 20B  Sunflower, oil                     0.450000   1.000  1.000

2002365001 20B  Sunflower, oil-babyfood            0.450000   1.000  1.000

2002364000 20B  Sunflower, seed                    0.450000   1.000  1.000

0103366000 1CD  Sweet potato                       0.040000   1.000  1.000

0103366001 1CD  Sweet potato-babyfood              0.040000   1.000  1.000

0402367000 4B   Swiss chard                       23.380000   1.000  1.000

1001369000 10A  Tangerine                          2.000000   1.000  1.000

1001370000 10A  Tangerine, juice                   2.000000   0.020  1.000

0103371000 1CD  Tanier, corm                       0.040000   1.000  1.000

0801374000 8A   Tomatillo                          1.400000   1.000  1.000

0801375000 8A   Tomato                             1.400000   1.000  1.000

0801380000 8A   Tomato, Tree                       1.400000   1.000  1.000

0801378000 8A   Tomato, dried                      1.400000  14.300  1.000

0801378001 8A   Tomato, dried-babyfood             1.400000  14.300  1.000

0801379000 8A   Tomato, juice                      1.400000   1.500  1.000

0801376000 8A   Tomato, paste                      1.400000   2.100  1.000

0801376001 8A   Tomato, paste-babyfood             1.400000   2.100  1.000

0801377000 8A   Tomato, puree                      1.400000   0.550  1.000

0801377001 8A   Tomato, puree-babyfood             1.400000   0.550  1.000

0801375001 8A   Tomato-babyfood                    1.400000   1.000  1.000

1500381000 15   Triticale, flour                   0.020000   0.700  1.000

1500381001 15   Triticale, flour-babyfood          0.020000   1.000  1.000

5000385000 50   Turkey, fat                        0.100000   1.000  1.000

5000385001 50   Turkey, fat-babyfood               0.100000   1.000  1.000

5000383000 50   Turkey, liver                      0.100000   1.000  1.000

5000383001 50   Turkey, liver-babyfood             0.100000   1.000  1.000

5000382000 50   Turkey, meat                       0.100000   1.000  1.000

5000384000 50   Turkey, meat byproducts            0.100000   1.000  1.000

5000384001 50   Turkey, meat byproducts-babyfood   0.100000   1.000  1.000

5000382001 50   Turkey, meat-babyfood              0.100000   1.000  1.000

5000386000 50   Turkey, skin                       0.100000   1.000  1.000

5000386001 50   Turkey, skin-babyfood              0.100000   1.000  1.000

0103387000 1CD  Turmeric                           0.040000   1.000  1.000

0502389000 5B   Turnip, greens                    16.000000   1.000  1.000

0101388000 1AB  Turnip, roots                      0.400000   1.000  1.000

1400391000 14   Walnut                             0.040000   1.000  1.000

8601000000 86A  Water, direct, all sources         0.035600   1.000  1.000

8602000000 86B  Water, indirect, all sources       0.035600   1.000  1.000

0901399000 9A   Watermelon                         0.500000   1.000  1.000

0901400000 9A   Watermelon, juice                  0.500000   1.000  1.000

1500404000 15   Wheat, bran                        0.020000   1.000  1.000

1500402000 15   Wheat, flour                       0.020000   0.700  1.000

1500402001 15   Wheat, flour-babyfood              0.020000   0.700  1.000

1500403000 15   Wheat, germ                        0.020000   0.850  1.000

1500401000 15   Wheat, grain                       0.020000   1.000  1.000

1500401001 15   Wheat, grain-babyfood              0.020000   1.000  1.000

0103407000 1CD  Yam bean                           0.040000   1.000  1.000

0103406000 1CD  Yam, true                          0.040000   1.000  1.000

Attachment 2.  Pyraclostrobin Acute Dietary Analysis Results – Food & Water

US EPA                                                      Ver. 3.16, 03-08-d

DEEM-FCID ACUTE Analysis for PYRACLOSTROBIN              NHANES 2003-2008 2-Day

Residue file: PyracloAcuteR08_04_15_13.R08        Adjustment factor #2 NOT used.

Analysis Date: 04-23-2013/07:06:22    Residue file dated: 04-23-2013/07:04:21

NOEL (Acute) = 300.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: "Food and drinking water"

======================================================================== =======

Summary calculations--per capita:

---   95th Percentile----   ---   99th Percentile----     ---99.9th Percentile----

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Total US Population:

  0.044721    1.49    6708    0.077398    2.58    3876    0.126870    4.23    2364

All Infants:

  0.061716    2.06    4860    0.094284    3.14    3181    0.253340    8.44    1184

Children 1-2:

  0.083049    2.77    3612    0.126814    4.23    2365    0.200895    6.70    1493

Children 3-5:

  0.074666    2.49    4017    0.124057    4.14    2418    0.201824    6.73    1486

Children 6-12:

  0.044251    1.48    6779    0.076218    2.54    3936    0.110749    3.69    2708

Youth 13-19:

  0.031506    1.05    9522    0.058879    1.96    5095    0.112688    3.76    2662

Adults 20-49:

  0.041724    1.39    7190    0.072384    2.41    4144    0.115778    3.86    2591

Adults 50-99:

  0.041722    1.39    7190    0.069793    2.33    4298    0.118280    3.94    2536

US EPA                                                      Ver. 3.16, 03-08-d

DEEM-FCID ACUTE Analysis for PYRACLOSTROBIN              NHANES 2003-2008 2-Day

Residue file: PyracloAcuteR08_04_15_13.R08        Adjustment factor #2 NOT used.

Analysis Date: 04-23-2013/07:08:44    Residue file dated: 04-23-2013/07:04:21

NOEL (Acute) =   5.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: "Food and drinking water"

======================================================================== =======

Summary calculations--per capita:

---   95th Percentile----   ---   99th Percentile----     ---99.9th Percentile----

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Female 13-49:

  0.043481   86.96     114    0.073936  147.87      67    0.120543  241.09      41

Attachment 3.  Pyraclostrobin Chronic Dietary Analysis Input File – Food & Water

Filename: C:\Documents and Settings\sfunk\My Documents\DEEMversion3.16\PyracloChronic04_15_13.R08

Chemical: Pyraclostrobin

RfD(Chronic): .034 mg/kg bw/day  NOEL(Chronic): 3.4 mg/kg bw/day

RfD(Acute): 3 mg/kg bw/day  NOEL(Acute):  300 mg/kg bw/day

Date created/last modified: 04-15-2013/10:38:44       Program ver. 3.16, 03-08-d

Comment: Food and drinking water

------------------------------------------------------------------------ -----------

   EPA     Crop                                   Def Res     Adj.Factors   Comment

   Code     Grp  Commodity Name                    (ppm)       #1    #2

---------- ---- -------------------------------  ----------  ------ ------  -------

1400003000 14   Almond                             0.040000   1.000  0.400

1400004000 14   Almond, oil                        0.040000   1.000  0.400

1400004001 14   Almond, oil-babyfood               0.040000   1.000  1.000

1400003001 14   Almond-babyfood                    0.040000   1.000  1.000

0401005000 4A   Amaranth, leafy                   11.770000   1.000  1.000

1100009000 11   Apple, dried                       0.310000   8.000  0.150

1100009001 11   Apple, dried-babyfood              0.310000   8.000  0.150

1100007000 11   Apple, fruit with peel             0.310000   1.000  0.150

1100010000 11   Apple, juice                       0.310000   0.200  0.150

1100010001 11   Apple, juice-babyfood              0.310000   0.200  0.150

1100008000 11   Apple, peeled fruit                0.310000   1.000  0.150

1100008001 11   Apple, peeled fruit-babyfood       0.310000   1.000  0.150

1100011000 11   Apple, sauce                       0.310000   1.000  0.150

1100011001 11   Apple, sauce-babyfood              0.310000   1.000  0.150

1202012000 12B  Apricot                            0.602000   1.000  0.250

1202013000 12B  Apricot, dried                     0.602000   6.000  0.250

1202014000 12B  Apricot, juice                     0.602000   1.000  0.250

1202014001 12B  Apricot, juice-babyfood            0.602000   1.000  0.250

1202012001 12B  Apricot-babyfood                   0.602000   1.000  0.250

0103015000 1CD  Arrowroot, flour                   0.040000   1.000  1.000

0103015001 1CD  Arrowroot, flour-babyfood          0.040000   1.000  1.000

0103017000 1CD  Artichoke, Jerusalem               0.040000   1.000  1.000

9500016000 O    Artichoke, globe                   0.840000   1.000  1.000

0401018000 4A   Arugula                           11.770000   1.000  1.000

9500020000 O    Avocado                            0.600000   1.000  1.000

0902021000 9B   Balsam pear                        0.500000   1.000  1.000

9500023000 O    Banana                             0.040000   1.000  1.000

9500024000 O    Banana, dried                      0.040000   3.900  1.000

9500024001 O    Banana, dried-babyfood             0.040000   3.900  1.000

9500023001 O    Banana-babyfood                    0.040000   1.000  1.000

1500027000 15   Barley, bran                       1.400000   1.000  0.100

1500026000 15   Barley, flour                      1.400000   1.000  0.100

1500026001 15   Barley, flour-babyfood             1.400000   1.000  0.100

1500025000 15   Barley, pearled barley             1.400000   1.000  0.100

1500025001 15   Barley, pearled barley-babyfood    1.400000   1.000  0.100

1901029000 19A  Basil, dried leaves               85.000000   1.000  1.000

1901029001 19A  Basil, dried leaves-babyfood      85.000000   1.000  1.000

1901028000 19A  Basil, fresh leaves               25.000000   1.000  1.000

1901028001 19A  Basil, fresh leaves-babyfood      25.000000   1.000  1.000

0603035000 6C   Bean,  great northern, seed        0.500000   1.000  0.100

0603030000 6C   Bean, black, seed                  0.500000   1.000  0.100

0603032000 6C   Bean, broad, seed                  0.500000   1.000  0.100

0602031000 6B   Bean, broad, succulent             0.500000   1.000  0.050

0603034000 6C   Bean, cowpea, seed                 0.500000   1.000  0.100

0602033000 6B   Bean, cowpea, succulent            0.500000   1.000  0.050

0603036000 6C   Bean, kidney, seed                 0.500000   1.000  0.100

0603038000 6C   Bean, lima, seed                   0.500000   1.000  0.100

0602037000 6B   Bean, lima, succulent              0.500000   1.000  0.050

0603039000 6C   Bean, mung, seed                   0.500000   1.000  0.100

0603040000 6C   Bean, navy, seed                   0.500000   1.000  0.100

0603041000 6C   Bean, pink, seed                   0.500000   1.000  0.100

0603042000 6C   Bean, pinto, seed                  0.050000   1.000  0.100

0601043000 6A   Bean, snap, succulent              0.500000   1.000  0.050

0601043001 6A   Bean, snap, succulent-babyfood     0.500000   1.000  0.050

3100047000 31   Beef, fat                          0.100000   1.000  1.000

3100047001 31   Beef, fat-babyfood                 0.100000   1.000  1.000

3100048000 31   Beef, kidney                       0.200000   1.000  1.000

3100049000 31   Beef, liver                        1.500000   1.000  1.000

3100049001 31   Beef, liver-babyfood               1.500000   1.000  1.000

3100044000 31   Beef, meat                         0.100000   1.000  1.000

3100046000 31   Beef, meat byproducts              0.200000   1.000  1.000

3100046001 31   Beef, meat byproducts-babyfood     0.200000   1.000  1.000

3100045000 31   Beef, meat, dried                  0.100000   1.920  1.000

3100044001 31   Beef, meat-babyfood                0.100000   1.000  1.000

0101050000 1AB  Beet, garden, roots                0.400000   1.000  1.000

0101050001 1AB  Beet, garden, roots-babyfood       0.400000   1.000  1.000

0200051000 2    Beet, garden, tops                16.000000   1.000  1.000

0101052000 1A   Beet, sugar                        0.200000   0.400  0.450

0101053000 1A   Beet, sugar, molasses              0.200000   0.400  0.450

0101053001 1A   Beet, sugar, molasses-babyfood     0.200000   0.400  0.450

0101052001 1A   Beet, sugar-babyfood               0.200000   0.400  0.450

9500054000 O    Belgium endive                     0.820000   1.000  1.000

1301055000 13A  Blackberry                         4.000000   1.000  0.500

1301056000 13A  Blackberry, juice                  4.000000   1.000  0.500

1301056001 13A  Blackberry, juice-babyfood         4.000000   1.000  0.500

1302057000 13B  Blueberry                          4.000000   1.000  0.450

1302057001 13B  Blueberry-babyfood                 4.000000   1.000  0.450

1301058000 13A  Boysenberry                        4.000000   1.000  0.500

1400059000 14   Brazil nut                         0.040000   1.000  1.000

0501061000 5A   Broccoli                           1.100000   1.000  0.050

0502063000 5B   Broccoli raab                     16.000000   1.000  1.000

0501062000 5A   Broccoli, Chinese                  5.000000   1.000  1.000

0501061001 5A   Broccoli-babyfood                  1.100000   1.000  0.050

0501064000 5A   Brussels sprouts                   5.000000   1.000  1.000

0101067000 1AB  Burdock                            0.400000   1.000  1.000

1400068000 14   Butternut                          0.040000   1.000  1.000

0501069000 5A   Cabbage                            5.000000   1.000  0.100

0502070000 5B   Cabbage, Chinese, bok choy        16.000000   1.000  1.000

0501072000 5A   Cabbage, Chinese, mustard          5.000000   1.000  1.000

0501071000 5A   Cabbage, Chinese, napa             5.000000   1.000  1.000

9500074000 O    Canistel                           0.600000   1.000  1.000

0901075000 9A   Cantaloupe                         0.500000   1.000  0.150

0402076000 4B   Cardoon                            5.020000   1.000  1.000

0101078000 1AB  Carrot                             0.400000   1.000  0.350

0101079000 1AB  Carrot, juice                      0.400000   1.000  0.350

0101078001 1AB  Carrot-babyfood                    0.400000   1.000  0.350

1400081000 14   Cashew                             0.040000   1.000  1.000

0103082000 1CD  Cassava                            0.040000   1.000  1.000

0103082001 1CD  Cassava-babyfood                   0.040000   1.000  1.000

0501083000 5A   Cauliflower                        5.000000   1.000  0.025

0101084000 1AB  Celeriac                           0.400000   1.000  1.000

0402085000 4B   Celery                             5.020000   1.000  0.025

0402086000 4B   Celery, juice                      5.020000   1.000  0.025

0402085001 4B   Celery-babyfood                    5.020000   1.000  0.025

0402087000 4B   Celtuce                            5.020000   1.000  1.000

0902088000 9B   Chayote, fruit                     0.500000   1.000  1.000

1201090000 12A  Cherry                             0.846000   1.000  0.500

1201091000 12A  Cherry, juice                      0.846000   1.500  0.500

1201091001 12A  Cherry, juice-babyfood             0.846000   1.500  0.500

1201090001 12A  Cherry-babyfood                    0.846000   1.000  0.500

1400092000 14   Chestnut                           0.040000   1.000  1.000

4000096000 40   Chicken, fat                       0.100000   1.000  1.000

4000096001 40   Chicken, fat-babyfood              0.100000   1.000  1.000

4000094000 40   Chicken, liver                     0.100000   1.000  1.000

4000093000 40   Chicken, meat                      0.100000   1.000  1.000

4000095000 40   Chicken, meat byproducts           0.100000   1.000  1.000

4000095001 40   Chicken, meat byproducts-babyfoo   0.100000   1.000  1.000

4000093001 40   Chicken, meat-babyfood             0.100000   1.000  1.000

4000097000 40   Chicken, skin                      0.100000   1.000  1.000

4000097001 40   Chicken, skin-babyfood             0.100000   1.000  1.000

0603099000 6C   Chickpea, flour                    0.340000   1.000  0.100

0603098000 6C   Chickpea, seed                     0.340000   1.000  0.100

0603098001 6C   Chickpea, seed-babyfood            0.340000   1.000  0.100

0101100000 1AB  Chicory, roots                     0.400000   1.000  1.000

0200101000 2    Chicory, tops                     16.000000   1.000  1.000

0902102000 9B   Chinese waxgourd                   0.500000   1.000  1.000

0302103000 3B   Chive, fresh leaves               25.000000   1.000  1.000

0401104000 4A   Chrysanthemum, garland            11.770000   1.000  1.000

1901118000 19A  Cilantro, leaves                  25.000000   1.000  1.000

1901118001 19A  Cilantro, leaves-babyfood         25.000000   1.000  1.000

1001106000 10A  Citron                             2.000000   1.000  1.000

1001107000 10A  Citrus hybrids                     2.000000   1.000  1.000

1001108000 10A  Citrus, oil                        9.000000   1.000  1.000

9500116000 O    Coffee, instant                    0.064000   1.000  1.000

9500115000 O    Coffee, roasted bean               0.064000   1.000  1.000

0502117000 5B   Collards                           5.740000   1.000  1.000

1500122000 15   Corn, field, bran                  0.100000   1.000  0.100

1500120000 15   Corn, field, flour                 0.100000   1.000  0.100

1500120001 15   Corn, field, flour-babyfood        0.100000   1.000  0.100

1500121000 15   Corn, field, meal                  0.100000   1.000  0.100

1500121001 15   Corn, field, meal-babyfood         0.100000   1.000  0.100

1500125000 15   Corn, field, oil                   0.200000   1.000  0.100

1500125001 15   Corn, field, oil-babyfood          0.200000   1.000  0.100

1500123000 15   Corn, field, starch                0.100000   1.000  0.100

1500123001 15   Corn, field, starch-babyfood       0.100000   1.000  0.100

1500124000 15   Corn, field, syrup                 0.100000   1.500  0.100

1500124001 15   Corn, field, syrup-babyfood        0.100000   1.500  1.000

1500126000 15   Corn, pop                          0.100000   1.000  1.000

1500127000 15   Corn, sweet                        0.040000   1.000  0.050

1500127001 15   Corn, sweet-babyfood               0.040000   1.000  0.050

2003128000 20C  Cottonseed, oil                    0.300000   1.000  0.025

2003128001 20C  Cottonseed, oil-babyfood           0.300000   1.000  0.025

1100129000 11   Crabapple                          1.500000   1.000  1.000

0401133000 4A   Cress, garden                     11.770000   1.000  1.000

0401134000 4A   Cress, upland                     11.770000   1.000  1.000

0902135000 9B   Cucumber                           0.500000   1.000  0.050

1302136000 13B  Currant                            4.000000   1.000  1.000

1302137000 13B  Currant, dried                     4.000000   1.000  1.000

0401138000 4A   Dandelion, leaves                 11.770000   1.000  1.000

0103139000 1CD  Dasheen, corm                      0.040000   1.000  1.000

0200140000 2    Dasheen, leaves                   16.000000   1.000  1.000

1902143000 19B  Dill, seed                        25.000000   1.000  1.000

1901144000 19A  Dillweed                          25.000000   1.000  1.000

7000146000 70   Egg, white                         0.100000   1.000  1.000

7000146001 70   Egg, white (solids)-babyfood       0.100000   1.000  1.000

7000145000 70   Egg, whole                         0.100000   1.000  1.000

7000145001 70   Egg, whole-babyfood                0.100000   1.000  1.000

7000147000 70   Egg, yolk                          0.100000   1.000  1.000

7000147001 70   Egg, yolk-babyfood                 0.100000   1.000  1.000

0802148000 8BC  Eggplant                           1.400000   1.000  1.000

1302149000 13B  Elderberry                         4.000000   1.000  1.000

0401150000 4A   Endive                            11.770000   1.000  1.000

0402152000 4B   Fennel, Florence                   5.020000   1.000  1.000

2001163000 20A  Flax seed, oil                     0.450000   1.200  1.000

0301165000 3A   Garlic, bulb                       0.900000   1.000  0.150

0301165001 3A   Garlic, bulb-babyfood              0.900000   1.000  0.150

0103166000 1CD  Ginger                             0.040000   1.000  1.000

0103167000 1CD  Ginger, dried                      0.040000   1.000  1.000

0103166001 1CD  Ginger-babyfood                    0.040000   1.000  1.000

0101168000 1AB  Ginseng, dried                     0.400000   1.000  1.000

3200171000 32   Goat, fat                          0.100000   1.000  1.000

3200172000 32   Goat, kidney                       0.200000   1.000  1.000

3200173000 32   Goat, liver                        1.500000   1.000  1.000

3200169000 32   Goat, meat                         0.100000   1.000  1.000

3200170000 32   Goat, meat byproducts              0.200000   1.000  1.000

1100173500 11   Goji berry                         1.500000   1.000  1.000

1302174000 13B  Gooseberry                         4.000000   1.000  1.000

1304175000 13D  Grape                              0.768000   1.000  0.300

1304176000 13D  Grape, juice                       0.768000   0.010  0.300

1304176001 13D  Grape, juice-babyfood              0.768000   0.010  0.300

9500177000 O    Grape, leaves                      0.768000   1.000  0.300

9500178000 O    Grape, raisin                      0.768000   1.000  0.300

1304179000 13D  Grape, wine and sherry             0.768000   1.000  0.300

1003180000 10C  Grapefruit                         2.000000   1.000  0.250

1003181000 10C  Grapefruit, juice                  2.000000   0.020  0.250

0603182000 6C   Guar, seed                         0.500000   1.000  0.100

0603182001 6C   Guar, seed-babyfood                0.500000   1.000  0.100

1400155000 14   Hazelnut                           0.040000   1.000  0.150

1400156000 14   Hazelnut, oil                      0.040000   1.000  1.000

1901184000 19A  Herbs, other                      25.000000   1.000  1.000

1901184001 19A  Herbs, other-babyfood             25.000000   1.000  1.000

1400185000 14   Hickory nut                        0.040000   1.000  1.000

0901187000 9A   Honeydew melon                     0.500000   1.000  1.000

9500188000 O    Hop                               23.000000   1.000  1.000

3300189000 33   Horse, meat                        0.100000   1.000  1.000

0101190000 1AB  Horseradish                        0.400000   1.000  1.000

1302191000 13B  Huckleberry                        4.000000   1.000  1.000

0502194000 5B   Kale                              16.000000   1.000  1.000

1304195000 13D  Kiwifruit, fuzzy                   0.768000   1.000  1.000

0501196000 5A   Kohlrabi                           5.000000   1.000  1.000

1002197000 10B  Kumquat                            2.000000   1.000  1.000

0302198000 3B   Leek                               0.900000   1.000  1.000

1002199000 10B  Lemon                              2.000000   1.000  0.025

1002200000 10B  Lemon, juice                       2.000000   0.020  0.025

1002200001 10B  Lemon, juice-babyfood              2.000000   0.020  0.025

1002201000 10B  Lemon, peel                        2.000000   1.000  0.025

1901202000 19A  Lemongrass                        25.000000   1.000  1.000

0603203000 6C   Lentil, seed                       0.500000   1.000  0.100

0401204000 4A   Lettuce, head                      0.590000   1.000  0.050

0401205000 4A   Lettuce, leaf                      7.680000   1.000  0.050

1002206000 10B  Lime                               2.000000   1.000  1.000

1002207000 10B  Lime, juice                        2.000000   0.020  1.000

1002207001 10B  Lime, juice-babyfood               2.000000   0.020  1.000

1301208000 13A  Loganberry                         4.000000   1.000  0.500

1100210000 11   Loquat                             1.500000   1.000  1.000

1400213000 14   Macadamia nut                      0.040000   1.000  1.000

9500215000 O    Mango                              0.600000   1.000  1.000

9500216000 O    Mango, dried                       0.600000   1.000  1.000

9500217000 O    Mango, juice                       0.600000   1.000  1.000

9500217001 O    Mango, juice-babyfood              0.600000   1.000  1.000

9500215001 O    Mango-babyfood                     0.600000   1.000  1.000

1901220000 19A  Marjoram                          25.000000   1.000  1.000

1901220001 19A  Marjoram-babyfood                 25.000000   1.000  1.000

3600222000 36   Milk, fat                          0.100000   1.000  1.000

3600222001 36   Milk, fat-baby food/infant formu   0.100000   1.000  1.000

3600223000 36   Milk, nonfat solids                0.100000   1.000  1.000

3600223001 36   Milk, nonfat solids-baby food/in   0.100000   1.000  1.000

3600225001 36   Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000

3600224000 36   Milk, water                        0.100000   1.000  1.000

3600224001 36   Milk, water-babyfood/infant form   0.100000   1.000  1.000

1303227000 13C  Mulberry                           4.000000   1.000  1.000

0502229000 5B   Mustard greens                     5.740000   1.000  1.000

1202230000 12B  Nectarine                          0.602000   1.000  0.100

1500231000 15   Oat, bran                          1.200000   1.000  1.000

1500232000 15   Oat, flour                         1.200000   1.000  1.000

1500232001 15   Oat, flour-babyfood                1.200000   1.000  1.000

1500233000 15   Oat, groats/rolled oats            1.200000   1.000  1.000

1500233001 15   Oat, groats/rolled oats-babyfood   1.200000   1.000  1.000

0802234000 8BC  Okra                               1.400000   1.000  1.000

0301237000 3A   Onion, bulb                        0.900000   1.000  0.200

0301238000 3A   Onion, bulb, dried                 0.900000   9.000  0.200

0301238001 3A   Onion, bulb, dried-babyfood        0.900000   9.000  0.200

0301237001 3A   Onion, bulb-babyfood               0.900000   1.000  0.200

0302239000 3B   Onion, green                       0.900000   1.000  0.200

1001240000 10A  Orange                             0.300000   1.000  0.050

1001241000 10A  Orange, juice                      0.300000   0.020  0.050

1001241001 10A  Orange, juice-babyfood             0.300000   0.020  0.050

1001242000 10A  Orange, peel                       0.300000   1.000  0.050

9500245000 O    Papaya                             0.600000   1.000  1.000

9500246000 O    Papaya, dried                      0.600000   1.800  1.000

9500247000 O    Papaya, juice                      0.600000   1.500  1.000

9500245001 O    Papaya-babyfood                    0.600000   1.000  1.000

1901249000 19A  Parsley, dried leaves             85.000000   1.000  1.000

1901249001 19A  Parsley, dried leaves-babyfood    85.000000   1.000  1.000

0401248000 4A   Parsley, leaves                   11.770000   1.000  1.000

0101250000 1AB  Parsley, turnip rooted             0.400000   1.000  1.000

0101251000 1AB  Parsnip                            0.400000   1.000  1.000

0101251001 1AB  Parsnip-babyfood                   0.400000   1.000  1.000

0603256000 6C   Pea, dry                           0.500000   1.000  0.100

0603256001 6C   Pea, dry-babyfood                  0.500000   1.000  0.100

0601257000 6A   Pea, edible podded, succulent      0.500000   1.000  1.000

0603258000 6C   Pea, pigeon, seed                  0.500000   1.000  0.100

0602259000 6B   Pea, pigeon, succulent             0.200000   1.000  0.050

0602255000 6B   Pea, succulent                     0.200000   1.000  0.050

0602255001 6B   Pea, succulent-babyfood            0.200000   1.000  0.050

1202260000 12B  Peach                              0.602000   1.000  0.200

1202261000 12B  Peach, dried                       0.602000   7.000  0.200

1202261001 12B  Peach, dried-babyfood              0.602000   7.000  0.200

1202262000 12B  Peach, juice                       0.602000   1.000  0.200

1202262001 12B  Peach, juice-babyfood              0.602000   1.000  0.200

1202260001 12B  Peach-babyfood                     0.602000   1.000  0.200

9500263000 O    Peanut                             0.050000   1.000  0.250

9500264000 O    Peanut, butter                     0.050000   1.890  0.250

9500265000 O    Peanut, oil                        0.100000   1.000  0.250

1100266000 11   Pear                               1.500000   1.000  0.150

1100267000 11   Pear, dried                        1.500000   6.250  0.150

1100268000 11   Pear, juice                        1.500000   1.000  0.150

1100268001 11   Pear, juice-babyfood               1.500000   1.000  0.150

1100266001 11   Pear-babyfood                      1.500000   1.000  0.150

1400269000 14   Pecan                              0.040000   1.000  0.025

0802270000 8B   Pepper, bell                       1.400000   1.000  0.100

0802271000 8B   Pepper, bell, dried                1.400000   1.000  0.100

0802271001 8B   Pepper, bell, dried-babyfood       1.400000   1.000  0.100

0802272000 8BC  Pepper, nonbell                    1.400000   1.000  0.100

0802273000 8BC  Pepper, nonbell, dried             1.400000   1.000  0.100

0802272001 8BC  Pepper, nonbell-babyfood           1.400000   1.000  0.100

9500275000 O    Peppermint                         8.000000   1.000  1.000

9500276000 O    Peppermint, oil                    8.000000   1.000  1.000

9500277000 O    Persimmon                          0.600000   1.000  1.000

1400278000 14   Pine nut                           0.040000   1.000  1.000

1400282000 14   Pistachio                          0.700000   1.000  0.300

9500283000 O    Plantain                           0.040000   1.000  1.000

9500284000 O    Plantain, dried                    0.040000   3.900  1.000

1203285000 12C  Plum                               0.198000   1.000  0.050

1203287000 12C  Plum, prune, dried                 0.198000   1.300  0.050

1203287001 12C  Plum, prune, dried-babyfood        0.198000   1.300  0.050

1203286000 12C  Plum, prune, fresh                 0.198000   1.000  0.050

1203286001 12C  Plum, prune, fresh-babyfood        0.198000   1.000  0.050

1203288000 12C  Plum, prune, juice                 0.198000   1.400  0.050

1203288001 12C  Plum, prune, juice-babyfood        0.198000   1.400  0.050

1203285001 12C  Plum-babyfood                      0.198000   1.000  0.050

3400293000 34   Pork, fat                          0.100000   1.000  1.000

3400293001 34   Pork, fat-babyfood                 0.100000   1.000  1.000

3400294000 34   Pork, kidney                       0.200000   1.000  1.000

3400295000 34   Pork, liver                        1.500000   1.000  1.000

3400290000 34   Pork, meat                         0.100000   1.000  1.000

3400292000 34   Pork, meat byproducts              0.200000   1.000  1.000

3400292001 34   Pork, meat byproducts-babyfood     0.200000   1.000  1.000

3400290001 34   Pork, meat-babyfood                0.100000   1.000  1.000

3400291000 34   Pork, skin                         0.100000   1.000  1.000

0103296000 1C   Potato, chips                      0.040000   1.000  0.150

0103297000 1C   Potato, dry (granules/ flakes)     0.040000   1.000  0.150

0103297001 1C   Potato, dry (granules/ flakes)-b   0.040000   1.000  0.150

0103298000 1C   Potato, flour                      0.040000   1.000  0.150

0103298001 1C   Potato, flour-babyfood             0.040000   1.000  0.150

0103300000 1C   Potato, tuber, w/o peel            0.040000   1.000  0.150

0103300001 1C   Potato, tuber, w/o peel-babyfood   0.040000   1.000  0.150

0103299000 1C   Potato, tuber, w/peel              0.040000   1.000  0.150

0103299001 1C   Potato, tuber, w/peel-babyfood     0.040000   1.000  0.150

6000304000 60   Poultry, other, fat                0.100000   1.000  1.000

6000302000 60   Poultry, other, liver              0.100000   1.000  1.000

6000301000 60   Poultry, other, meat               0.100000   1.000  1.000

6000303000 60   Poultry, other, meat byproducts    0.100000   1.000  1.000

6000305000 60   Poultry, other, skin               0.100000   1.000  1.000

1003307000 10C  Pummelo                            2.000000   1.000  1.000

0902308000 9B   Pumpkin                            0.500000   1.000  0.200

0902309000 9B   Pumpkin, seed                      0.500000   1.000  0.200

1100310000 11   Quince                             1.500000   1.000  1.000

0401313000 4A   Radicchio                          0.590000   1.000  1.000

0101316000 1AB  Radish, Oriental, roots            0.400000   1.000  1.000

0200317000 2    Radish, Oriental, tops            16.000000   1.000  1.000

0101314000 1AB  Radish, roots                      0.400000   1.000  1.000

0200315000 2    Radish, tops                      16.000000   1.000  1.000

0502318000 5B   Rape greens                       16.000000   1.000  1.000

2001319000 20A  Rapeseed, oil                      0.450000   1.000  1.000

2001319001 20A  Rapeseed, oil-babyfood             0.450000   1.000  1.000

1301320000 13A  Raspberry                          4.000000   1.000  0.500

1301321000 13A  Raspberry, juice                   4.000000   1.000  0.500

1301321001 13A  Raspberry, juice-babyfood          4.000000   1.000  0.500

1301320001 13A  Raspberry-babyfood                 4.000000   1.000  0.500

0402322000 4B   Rhubarb                            5.020000   1.000  1.000

0101327000 1AB  Rutabaga                           0.400000   1.000  1.000

1500329000 15   Rye, flour                         0.040000   1.000  1.000

1500328000 15   Rye, grain                         0.040000   1.000  1.000

2002330000 20B  Safflower, oil                     0.450000   1.000  1.000

2002330001 20B  Safflower, oil-babyfood            0.450000   1.000  1.000

0101331000 1AB  Salsify, roots                     0.400000   1.000  1.000

0200332000 2    Salsify, tops                     16.000000   1.000  1.000

9500333000 O    Sapote, Mamey                      0.600000   1.000  1.000

1901334000 19A  Savory                            25.000000   1.000  1.000

2001337000 20A  Sesame, oil                        0.450000   1.000  1.000

2001337001 20A  Sesame, oil-babyfood               0.450000   1.000  1.000

2001336000 20A  Sesame, seed                       0.450000   1.000  1.000

2001336001 20A  Sesame, seed-babyfood              0.450000   1.000  1.000

0301338000 3A   Shallot, bulb                      0.900000   1.000  1.000

0302338500 3B   Shallot, fresh leaves              0.900000   1.000  1.000

3500341000 35   Sheep, fat                         0.100000   1.000  1.000

3500341001 35   Sheep, fat-babyfood                0.100000   1.000  1.000

3500342000 35   Sheep, kidney                      0.200000   1.000  1.000

3500343000 35   Sheep, liver                       1.500000   1.000  1.000

3500339000 35   Sheep, meat                        0.100000   1.000  1.000

3500340000 35   Sheep, meat byproducts             0.200000   1.000  1.000

3500339001 35   Sheep, meat-babyfood               0.100000   1.000  1.000

1500344000 15   Sorghum, grain                     0.090000   1.000  1.000

1500345000 15   Sorghum, syrup                     0.090000   1.000  1.000

0603348000 6C   Soybean, flour                     0.040000   1.000  0.050

0603348001 6C   Soybean, flour-babyfood            0.040000   1.000  0.050

0600350000 6    Soybean, oil                       0.040000   1.000  0.050

0600350001 6    Soybean, oil-babyfood              0.040000   1.000  0.050

0600347000 6    Soybean, seed                      0.040000   1.000  0.050

0600349000 6    Soybean, soy milk                  0.040000   1.000  0.050

0600349001 6    Soybean, soy milk-babyfood or in   0.040000   1.000  0.050

9500352000 O    Spearmint                          8.000000   1.000  1.000

9500353000 O    Spearmint, oil                     8.000000   1.000  1.000

0401355000 4A   Spinach                           11.770000   1.000  0.050

0401355001 4A   Spinach-babyfood                  11.770000   1.000  0.050

0902356000 9B   Squash, summer                     0.500000   1.000  0.150

0902356001 9B   Squash, summer-babyfood            0.500000   1.000  0.150

0902357000 9B   Squash, winter                     0.500000   1.000  0.150

0902357001 9B   Squash, winter-babyfood            0.500000   1.000  0.150

1307359000 13G  Strawberry                         1.200000   1.000  0.650

1307360000 13G  Strawberry, juice                  1.200000   1.000  0.650

1307360001 13G  Strawberry, juice-babyfood         1.200000   1.000  0.650

1307359001 13G  Strawberry-babyfood                1.200000   1.000  0.650

9500363000 O    Sugarcane, molasses                0.076000   0.150  1.000

9500363001 O    Sugarcane, molasses-babyfood       0.076000   0.150  1.000

9500362000 O    Sugarcane, sugar                   0.076000   0.150  1.000

9500362001 O    Sugarcane, sugar-babyfood          0.076000   0.150  1.000

2002365000 20B  Sunflower, oil                     0.450000   1.000  1.000

2002365001 20B  Sunflower, oil-babyfood            0.450000   1.000  1.000

2002364000 20B  Sunflower, seed                    0.450000   1.000  1.000

0103366000 1CD  Sweet potato                       0.040000   1.000  1.000

0103366001 1CD  Sweet potato-babyfood              0.040000   1.000  1.000

0402367000 4B   Swiss chard                        5.020000   1.000  1.000

1001369000 10A  Tangerine                          2.000000   1.000  0.100

1001370000 10A  Tangerine, juice                   2.000000   0.020  0.100

0103371000 1CD  Tanier, corm                       0.040000   1.000  1.000

0801374000 8A   Tomatillo                          0.158000   1.000  1.000

0801375000 8A   Tomato                             0.158000   1.000  0.250

0801378000 8A   Tomato, dried                      0.158000  14.300  0.250

0801378001 8A   Tomato, dried-babyfood             0.158000  14.300  0.250

0801379000 8A   Tomato, juice                      0.158000   1.500  0.250

0801376000 8A   Tomato, paste                      0.158000   2.100  0.250

0801376001 8A   Tomato, paste-babyfood             0.158000   2.100  0.250

0801377000 8A   Tomato, puree                      0.158000   0.550  0.250

0801377001 8A   Tomato, puree-babyfood             0.158000   0.550  0.250

0801375001 8A   Tomato-babyfood                    0.158000   1.000  0.250

1500381000 15   Triticale, flour                   0.020000   0.700  1.000

1500381001 15   Triticale, flour-babyfood          0.020000   1.000  1.000

5000385000 50   Turkey, fat                        0.100000   1.000  1.000

5000385001 50   Turkey, fat-babyfood               0.100000   1.000  1.000

5000383000 50   Turkey, liver                      0.100000   1.000  1.000

5000383001 50   Turkey, liver-babyfood             0.100000   1.000  1.000

5000382000 50   Turkey, meat                       0.100000   1.000  1.000

5000384000 50   Turkey, meat byproducts            0.100000   1.000  1.000

5000384001 50   Turkey, meat byproducts-babyfood   0.100000   1.000  1.000

5000382001 50   Turkey, meat-babyfood              0.100000   1.000  1.000

5000386000 50   Turkey, skin                       0.100000   1.000  1.000

5000386001 50   Turkey, skin-babyfood              0.100000   1.000  1.000

0103387000 1CD  Turmeric                           0.040000   1.000  1.000

0502389000 5B   Turnip, greens                    16.000000   1.000  1.000

0101388000 1AB  Turnip, roots                      0.400000   1.000  1.000

1400391000 14   Walnut                             0.040000   1.000  0.010

8601000000 86A  Water, direct, all sources         0.002300   1.000  1.000

8602000000 86B  Water, indirect, all sources       0.002300   1.000  1.000

0901399000 9A   Watermelon                         0.500000   1.000  0.300

0901400000 9A   Watermelon, juice                  0.500000   1.000  0.300

1500404000 15   Wheat, bran                        0.020000   1.000  0.050

1500402000 15   Wheat, flour                       0.020000   0.700  0.050

1500402001 15   Wheat, flour-babyfood              0.020000   0.700  0.050

1500403000 15   Wheat, germ                        0.020000   0.850  0.050

1500401000 15   Wheat, grain                       0.020000   1.000  0.050

1500401001 15   Wheat, grain-babyfood              0.020000   1.000  0.050

0103407000 1CD  Yam bean                           0.040000   1.000  1.000

0103406000 1CD  Yam, true                          0.040000   1.000  1.000

Attachment 4.  Pyraclostrobin Chronic Dietary Analysis Results – Food & Water

US EPA                                                          Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for PYRACLOSTROBIN              NHANES 2003-2008 2-day

Residue file name: C:\Documents and Settings\sfunk\My Documents\DEEMversion3.16\PyracloChronic04_15_13.R08                                                     Adjustment factor #2 used.

Analysis Date 04-23-2013/07:12:23     Residue file dated: 04-23-2013/07:11:41

Reference dose (RfD, Chronic) = .034 mg/kg bw/day

COMMENT 1: Food and drinking water

======================================================================== =======

                    Total exposure by population subgroup

------------------------------------------------------------------------ -------

                                                    Total Exposure

                                         -----------------------------------

          Population                         mg/kg             Percent of

           Subgroup                       body wt/day             Rfd

--------------------------------------   -------------       ----------------

Total US Population                         0.002707                 8.0%

Hispanic                                    0.002691                 7.9%

Non-Hisp-White                              0.002669                 7.8%

Non-Hisp-Black                              0.002711                 8.0%

Non-Hisp-Other                              0.003270                 9.6%

Nursing Infants                             0.002498                 7.3%

Non-Nursing Infants                         0.005182                15.2%

Female 13+ PREG                             0.002189                 6.4%

Children 1-6                                0.007078                20.8%

Children 7-12                               0.003255                 9.6%

Male 13-19                                  0.001989                 5.8%

Female 13-19/NP                             0.001683                 5.0%

Male 20+                                    0.002326                 6.8%

Female 20+/NP                               0.002153                 6.3%

Seniors 55+                                 0.002196                 6.5%

All Infants                                 0.004353                12.8%

Female 13-50                                0.002005                 5.9%

Children 1-2                                0.009206                27.1%

Children 3-5                                0.006204                18.2%

Children 6-12                               0.003525                10.4%

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Youth 13-19                                 0.001832                 5.4%

Adults 20-49                                0.002224                 6.5%

Adults 50-99                                0.002252                 6.6%

Female 13-49                                0.002005                 5.9%

Attachment 5.  Pyraclostrobin Screening Level Usage Analysis (SLUA)

Pyraclostrobin	Dietary Exposure and Risk Assessment	DP Number: 410739

________________________________________________________________________ ___________

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