2,4 D Case 0073 Reregistration Eligibility Decision: Product Chemistry Considerations ( DP Barcode D287660)

July 8, 2003 Contract No. 68 D4 0010 Submitted to: U. S. Environmental Protection Agency Arlington, VA Submitted by: Dynamac Corporation 20440 Century Boulevard, Suite 100 Germantown, MD 20874 O Cl Cl OH O O Cl Cl O O Na+

O Cl Cl O O[ NH 2( CH 2 CH 2 OH) 2]+ O Cl Cl O O[ NH 2( CH 2) 2]+ 2,4 D REREGISTRATION ELIGIBILITY DECISION:

PRODUCT CHEMISTRY CONSIDERATIONS ( DP BARCODE D287660)

Case No. 0073 DESCRIPTION OF CHEMICAL 2,4 D ( 2,4 dichlorophenoxy acetic acid) is an herbicide, a plant growth regulator, and a fungicide. It is mainly used as a selective postemergence herbicide for the control of certain weed species on a variety of food/ feed sites including field, fruit, and vegetable crops.

Chemical structures and information are presented below for 2,4 D acid and those salts and esters with registered manufacturing use and/ or end use products ( MPs/ EPs) being supported by 2,4 D Task Force II. A list of salt and ester active ingredients which have been canceled or which are not being supported for reregistration follows.

2,4 D active ingredients with registered MPs/ EPs 2,4 D acid Empirical Formula: C8H6Cl2O3 Molecular Weight: 221.0 CAS Registry No.: 94 75 7 PC Code: 030001 2,4 D sodium salt ( Na) Empirical Formula: C8H5Cl2NaO3 Molecular Weight: 243.03 CAS Registry No.: 2702 72 9 PC Code: 030004 2,4 D diethanolamine salt ( DEA) Empirical Formula: C12H17Cl2NO5 Molecular Weight: 326.18 CAS Registry No.: 5742 19 8 PC Code: 030016 2,4 D dimethylamine salt ( DMA) Empirical Formula: C10H13Cl2NO3 Molecular Weight: 266.13 CAS Registry No.: 2008 39 1 PC Code: 030019 2,4 D active ingredients with registered MPs/ EPs 2 O Cl Cl O O CH 3 CH 3 O Cl Cl O O NH+( CH 2 CHOHCH 3) 3 O Cl Cl O O O CH 3 Cl Cl O O CH 3 O CH 3 Cl Cl O O O  [ NH 3 CH( CH 3) 2]+ 2,4 D isopropylamine salt ( IPA) Empirical Formula: C11H15Cl2NO3 Molecular Weight: 280.04 CAS Registry No.: 5742 17 6 PC Code: 030025 2,4 D triisopropanolamine salt ( TIPA) Empirical Formula: C17H27Cl2NO6 Molecular Weight: 412.31 CAS Registry No.: 32341 80 3 PC Code: 030035 2,4 D 2 butoxyethyl ester ( BEE) Empirical Formula: C14H18Cl2O4 Molecular Weight: 321.20 CAS Registry No.: 1929 73 3 PC Code: 030053 2,4 D 2 ethylhexyl ester ( 2 EHE) 1 Empirical Formula: C16H22Cl2O3 Molecular Weight: 333.27 CAS Registry No.: 1928 43 4 PC Code: 030063 2,4 D isopropyl ester ( IPE) Empirical Formula: C11H12Cl2O3 Molecular Weight: 263.12 CAS Registry No.: 94 11 1 PC Code: 030066 1 Formerly identified as the isooctyl ester. 3 2,4 D active ingredients that are canceled or not supported for reregistration 1: Active ingredient ( PC Code)

lithium salt ( 030002) ammonium salt ( 030005) alkanolamine salt of the ethanol and isopropanol ( 030010)

alkylamine ( C12) salt ( 030011) alkylamine ( C14) salt ( 030013) alkylamine salt, derived from tall oil ( 030014)

diethylamine salt ( 030017) N, N dimethyloleylamine salt ( 030020) ethanolamine salt ( 030021)

heptylamine salt ( 030023) isopropanolamine salt ( 030024) morpholine salt ( 030028)

N oleyl 1,3 propylenediamine salt ( 030029) octylamine salt ( 030030) triethanolamine salt ( 030033)

triethylamine salt ( 030034) N, N dimethyloleyl linoleylamine salt ( 030039) butoxyethoxypropyl ester ( 030052)

butoxypropyl ester ( 030055) butyl ester ( 030056) isobutyl ester ( 030062)

isooctyl ( 2 ethyl 4 methylpentyl) ester ( 030064) isooctyl ( 2 octyl) ester ( 030065) propylene glycol butyl ether ester ( 030072)

1 Source: Status of Pesticide in Registration, Reregistration, and Special Review ( Rainbow Report; 1998). The lithium salt is listed as unsupported for reregistration; remaining active ingredients have been canceled.

IDENTIFICATION OF ACTIVE INGREDIENT Available data concerning identification of the active ingredient are summarized in Table 1 for 2,4 D acid, salts, and esters with registered MPs/ EPs. 4 ( continued; footnotes follow)

Table 1. Available data concerning identification of the active ingredient. 1 Active ingredient ( PC Code) Color Physical State Melting Point/

Boiling Point Density/ Specific Gravity Octanol/ Water Partition Coeff. Vapor Pressure Solubility 2,4 D acid ( 030001) white crystalline solid m. p. 138 141 C s. g.= 1.416 at 25 C Log KO/ W 0.001 M sol'n pH 5 2.14 pH 7 0.177 pH 9 0.102 1.4 x 10 7 mm Hg at 25 C water = 569 mg/ L at 20 C g/ 100 g at 25 C acetone = 85.0 benzene = 1.07 diethyl ether = 220 ethanol = 130.0 isopropanol = 31.6 toluene = 0.067 xylene = 0.58 2,4 D Na salt ( 030004) white powder m. p. 200 C bulk = 42.2 lb/ ft3 at 25 C N/ A 2; salt dissociates to acid in water water = 4.5 g/ 100 mL at 25 C 2,4 D DEA salt ( 030016) cream powder m. p. 83 C bulk = 0.762 g/ cm3 at 25 C 2.24 x 10 2 at 25 C < 1.33 x 10 5 Pa at 25 C mg/ g at 25 C water = 806 acetonitrile = 47 ethanol = 280 n octanol = 36 2,4 D DMA salt ( 030019) amber aqueous liquid m. p. 118 120 C ( PAI) s. g. = 1.23 at 20 C N/ A; salt dissociates to acid in water < 1 x 10 7 mm Hg at 26 C g/ 100 mL at 20 C water = 72.9 ( pH 7)

acetonitrile = 1.06 hexane = 3.59 methanol = > 50 g/ 100 g n octanol = 5.41 toluene = 0.165 Table 1 ( continued)

Active ingredient ( PC Code) Color Physical State Melting Point/

Boiling Point Density/ Specific Gravity Octanol/ Water Partition Coeff. Vapor Pressure Solubility 5 ( continued; footnotes follow)

2,4 D IPA salt ( 030025) amber aqueous liquid m. p. 121 C ( PAI) s. g. = 1.15 at 20 C N/ A; salt dissociates to acid in water g/ 100 mL at 20 C water = 17.4 ( pH 5.3)

acetonitrile = 2.16 hexane = 0.00436 methanol = > 50 g/ 100 g n octanol = 3.11 toluene = 0.336 2,4 D TIPA salt ( 030035) amber aqueous liquid m. p. 87 110 C ( PAI) s. g. = 1.21 at 20 C N/ A; salt dissociates to acid in water g/ 100 mL at 20 C water = 46.1 ( pH 7)

acetonitrile = 12.3 Isopropanol = 14.4 Acetone = 11.7 methanol = > 50 g/ 100 g n octanol = 7.6 toluene = 0.6 2,4 D BEE ( 030053) dark amber liquid b. p. 89 C s. g. = 1.225 at 20 C log = 4.13 4.17 at 25 C 2.4 x 10 6 mm Hg at 25 C g/ 100 mL at 20 C water = insoluble acetone = > 53.6 acetonitrile = > 48.6 hexane = > 46.3 methanol = > 49.6 2,4 D 2 EHE ( 030063) dark amber liquid b. p. 300 C s. g. = 1.152 at 20 C log = 5.78 ( temp N/ A) 3.6 x 10 6 mm Hg ( temp N/ A) water = 86.7 ppb g/ 100 mL at 20 C acetone = > 54.0 acetonitrile = > 49.1 hexane = > 45.7 methanol = > 52.3 Table 1 ( continued)

Active ingredient ( PC Code) Color Physical State Melting Point/

Boiling Point Density/ Specific Gravity Octanol/ Water Partition Coeff. Vapor Pressure Solubility 6 2,4 D IPE ( 030066) pale amber liquid b. p. 240 C s. g. = 1.252 at 25 C 253.8 ± 44.4 ( temp N/ A) 5.3 x 10 6 mbar water = 0.023 g/ 100 mL fully miscible in dichloromethane, hexane,

isopropanol, and toluene 1 Data assembled from Agency memoranda and comprehensive review documents referenced herein, including the 2,4 D Reregistration Standard.

2 N/ A = Not available. 7 MANUFACTURING USE PRODUCTS A search of the Reference Files System ( REFS) conducted 3/ 13/ 03 identified 50 2,4 D MPs registered under PC Codes 030001 ( acid), 030004 ( Na salt), 030019 ( DMA salt), 030025 ( IPA salt), 030035 ( TIPA salt), 030053 ( BEE), 030063 ( 2 EHE), and 030066 ( IPE). In addition, REFS lists three EPs under PC Code 030016, which are apparently produced from unregistered TGAIs. The 030016 TGAIs are subject to a reregistration eligibility decision in support of reregistration of the diethanolamine salt. A list of the registered MPs subject to a reregistration eligibility decision is presented in Table 2. 8 Table 2. Registered manufacturing use products of 2,4 D ( Case 0073).

Product 1 EPA Reg. No. Registrant 2 Comments/ Transfers 2,4 D acid ( 030001)

97% acid T ( r) 228 361 NuFarm Americas, Inc. Formerly Riverdale Chemical Company 95% acid T ( r) 228 360 95% acid T ( r) 228 314 98.2% acid T 2217 455 37.6% acid FI 2217 615 26.9% acid FI 2217 621 11.6% acid FI 2217 567 PBI/ Gordon Corporation 10.956% acid FI 2217 593 10% acid FI 2217 508 1.7% acid T 5481 144 Amvac Chemical Corporation This product is an MAI which is also listed under 2,4 D isopropyl ester ( 030066)

as the 95% IPE T; data requirements are specified in the data summary table for the 95% IPE T.

98% acid T ( r) 7969 171 BASF Corporation To be transferred to NuFarm.

97% acid T ( r) 7969 174 99.3% acid T ( r) 34704 798 Platte Chemical Company,

Inc.

97% acid T ( r) 34704 797 95% acid T 35935 7 NuFarm Limited Transferred 1/ 25/ 96 from Agrolinz, Inc., EPA Reg. No. 42545 8.

97.9% acid T 46146 3 Atanor S. A. Transferred 3/ 2/ 00 from R. A. M. Research, Inc., EPA Reg. No. 69474 1;

transferred 11/ 28/ 95 from Albaugh, Inc., EPA Reg. No. 42750 31; transferred 3/ 15/ 94 from A H Marks and Company, Ltd. ( EPA Reg. No. 15440 15). Table 2 ( continued)

Product 1 EPA Reg. No. Registrant 2 Comments/ Transfers 9 97.9% acid T ( r) 48273 22 Marman USA, Inc.

95% acid T 61272 5 NuFarm USA, Inc. Transferred 5/ 5/ 89 from Platte Chemical Company, Inc., EPA Reg. No. 34704

76.

95% acid T 61272 3 Transferred 1/ 25/ 89 from Farmland Industries, Inc., EPA Reg. No. 1990 390.

97.9% acid T 61469 2 Agro Gor Corporation Transferred 5/ 17/ 95 from Agrolinz, Inc., EPA Reg. No. 42545 30; transferred 11/ 1/ 83 from Rhone Poulenc Agrochemical Division ( EPA Reg. No. 359 579).

97.9% acid T 61469 1 Transferred 1/ 13/ 89 from PBI/ Gordon Corporation, EPA Reg. No. 2217 632.

97% acid T 62719 25 Dow AgroSciences LLC Formerly Dow Chemical Company, EPA Reg. No. 464 454 ( 12/ 4/ 89).

85% acid FI ( r) 62719 231 74.8% acid T 62719 24 This product is incorrectly identified as a formulation intermediate in REFS.

Formerly Dow Chemical Company, EPA Reg. No. 464 453 ( 12/ 4/ 89).

99.3% acid T 72868 1 BASF Aktiengesellschaft Agricultural Center Transferred 11/ 10/ 99 from Rhone Poulenc AG Co., EPA Reg. No. 264 492;

transferred 4/ 25/ 88 from Rhone Poulenc Agrochemical Division, EPA Reg. No.

359 734; transferred 11/ 13/ 86 from Maxus Agri Chem'l ( EPA Reg. No.

39335 30). To be transferred to NuFarm.

98.2% acid T ( r) 73754 1 GroWell Limited 2,4 D sodium salt ( 030004)

90.6% Na T 228 123 NuFarm Americas, Inc. Formerly Riverdale Chemical Company.

90.6% Na T ( r) 35935 19 NuFarm Limited Transferred 9/ 4/ 96 from Riverdale Chemical Company, EPA Reg. No. 228 319.

2,4 D diethanolamine salt ( 030016)

No registered manufacturing use products; however, data are required for the practical equivalent of the TGAI to support three end use products. Table 2 ( continued)

Product 1 EPA Reg. No. Registrant 2 Comments/ Transfers 10 2,4 D dimethylamine salt ( 030019)

66.3% DMA FI 228 294 NuFarm Americas, Inc. Formerly Riverdale Chemical Company; transferred 8/ 22/ 94 from Helena Chemical Company, EPA Reg. No. 5905 509; transferred 10/ 2/ 90 from Setre Chemical Company, EPA Reg. No. 38167 25; transferred 6/ 30/ 89 from Inter Ag Corporation, EPA Reg. No. 57539 24; transferred 3/ 20/ 87 from Vertac Chemical Corporation, EPA Reg. No. 39511 84.

31.8% DMA FI 239 2485 The Ortho Business Group Formerly Solaris Group of Monsanto Co.

66.57% DMA FI 2217 665 PBI/ Gordon Corporation 46.4% DMA FI 2217 654 61.37% DMA FI 35935 11 NuFarm Limited Transferred 1/ 25/ 96 from Agrolinz, Inc., EPA Reg. No. 42545 36; transferred 11/ 1/ 83 from Rhone Poulenc Agrochemical Division, EPA Reg. No. 359 673.

66.18% DMA FI 61272 8 NuFarm USA, Inc. Transferred 5/ 5/ 89 from Platte Chemical Company, Inc., EPA Reg. No. 34704

83.

67.1% DMA FI 62719 27 Dow AgroSciences LLC Formerly Dow Chemical Company, EPA Reg. No. 464 467 ( 12/ 4/ 89).

66.8% DMA FI 62719 52 Formerly Dow Chemical Company, EPA Reg. No. 464 568 ( 12/ 4/ 89).

2,4 D isopropylamine salt ( 030025)

49.9% IPA T 62719 71 Dow AgroSciences LLC This product is incorrectly identified as an FI in REFS.

Formerly Dow Chemical Company, EPA Reg. No. 464 596 ( 12/ 4/ 89).

2,4 D triisopropanolamine salt ( 030035)

71% TIPA FI 62719 180 Dow AgroSciences LLC 2,4 D 2 butoxyethyl ester ( 030053)

94% BEE T 228 136 NuFarm Americas, Inc. Formerly Riverdale Chemical Company Table 2 ( continued)

Product 1 EPA Reg. No. Registrant 2 Comments/ Transfers 11 94.5% BEE T 62719 33 Dow AgroSciences LLC Formerly Dow Chemical Company, EPA Reg. No. 464 518 ( 12/ 4/ 89).

2,4 D 2 ethylhexyl ester ( 030063)

93.3% 2 EHE T 2217 706 PBI/ Gordon Corporation Transferred 12/ 6/ 83 from Falls Chemical, Inc., EPA Reg. No. 40831 119.

94% 2 EHE T 35935 12 NuFarm Limited Transferred 1/ 25/ 96 from Agrolinz, Inc., EPA Reg. No. 42545 40; transferred 12/ 12/ 83 from Rhone Poulenc Agrochemical Division, EPA Reg. No. 359 577.

93.3% 2 EHE T 46146 5 Atanor S. A. This product is incorrectly identified as an FI in REFS.

Transferred 3/ 9/ 00 from R. A. M. Research Inc., EPA Reg. No. 69474 3;

transferred 12/ 23/ 99 from PBI/ Gordon Corp., EPA Reg. No. 2217 804;

transferred 12/ 13/ 95 from Albaugh, Inc., EPA Reg. No. 42750 35; transferred 5/ 18/ 95 from Helena Chemical Company, EPA Reg. No. 5905 500; transferred 10/ 2/ 90 from Setre Chemical Company, EPA Reg. No. 38167 16; transferred 6/ 30/ 89 from Inter Ag Corporation, EPA Reg. No. 57539 6; transferred 3/ 20/ 87 from Vertac Chemical Corporation, EPA Reg. No. 39511 62.

93.3 2 EHE T 46146 4 This product is incorrectly identified as an FI in REFS.

Transferred 3/ 2/ 00 from R. A. M. Research, Inc., EPA Reg. No. 69474 2;

transferred 11/ 28/ 95 from Albaugh, Inc., EPA Reg. No. 42750 9; transferred 11/ 17/ 87 from GB Biosciences Corporation, EPA Reg. No. 50534 130;

transferred 5/ 8/ 84 from Occidental Chemical Corporation, EPA Reg. No. 677

255.

98% 2 EHE T 61272 1 NuFarm USA, Inc. Transferred 1/ 25/ 89 from Farmland Industries, Inc., EPA Reg. No. 1990 338.

95% 2 EHE T 61272 7 Transferred 5/ 5/ 89 from Platte Chemical Company, Inc., EPA Reg. No. 34704

81.

95.4% 2 EHE T 62719 26 Dow AgroSciences LLC Formerly Dow Chemical Company, EPA Reg. No. 464 458 ( 12/ 4/ 89).

93.3% 2 EHE T ( r) 73754 2 GroWell Limited Table 2 ( continued)

Product 1 EPA Reg. No. Registrant 2 Comments/ Transfers 12 2,4 D isopropyl ester ( 030066)

95% IPE T 5481 144 Amvac Chemical Corporation 94% IPE FI 35935 13 NuFarm Limited Transferred 1/ 25/ 96 from Agrolinz, Inc., EPA Reg. No. 42545 50.

1 ( r) = Repackaged product.

2 Dow AgroSciences LLC, Agro Gor Corporation [ PBI/ Gordon and Atanor S. A.], and NuFarm USA, Inc. are the current members of the Industry Task Force II on 2,4 D Research Data ( TF II). 13 REGULATORY BACKGROUND The Product Chemistry Chapter of the 2,4 D Reregistration Standard dated 2/ 16/ 88 and subsequent Guidance Document dated 9/ 88 required that updated generic and product specific product chemistry data be submitted for 2,4 D acid and each salt, ester, and amine derivative. In addition, a Data Call In ( DCI) dated 6/ 15/ 87 required analytical chemistry data for polyhalogenated dibenzo p dioxin/ dibenzofuran ( PHDD/ PHDF) contaminants in 2,4 D and its salts and esters.

The current status of the product chemistry data requirements for the 2,4 D acid, salt, and ester TGAIs/ MPs is presented in the attached data summary tables. Refer to these tables for a listing of the outstanding product chemistry data requirements. These requirements pertain to each product's respective registrant and not the Task Force II as a whole.

We note that data submitted by A H Marks for an as yet unregistered BASF Corporation 97.5% 2 EHE T ( 2001; MRIDs 45377501 45377506) are not presented herein because these are newproduct registration data and do not pertain to the reregistration of 2,4 D.

CONCLUSIONS The outstanding product chemistry data requirements for the 2,4 D acid, salt, and ester products are summarized in Table 3, and are detailed in the attached data summary table. Provided that the registrants submit the data required in the attached data summary tables for their T/ TGAI and FI products, and either certify that the suppliers of beginning materials and the manufacturing processes for the 2,4 D manufacturing use products have not changed since the last comprehensive product chemistry reviews or submit complete updated product chemistry data packages, HED has no objections to the reregistration of 2,4 D and its salts and esters with respect to product chemistry data requirements. 14 Table 3. Remaining Product Chemistry Data Requirements for 2,4 D acid, salt, and ester TGAIs/ MPs.

TGAI/ MP 1 EPA Reg. No. Registrant Outstanding OPPTS Guideline Requirements 2 2,4 D acid ( 030001)

97% acid T ( r) 228 361 NuFarm Americas, Inc. Repackaged  Data requirements will be satisfied by data for the source product 95% acid T ( r) 228 360 Repackaged  Data requirements will be satisfied by data for the source product 95% acid T ( r) 228 314 Repackaged  Data requirements will be satisfied by data for the source product 98.2% acid T 2217 455 None 37.6% acid FI 2217 615 830.1550, 1600, 1650, 1670, 1750, 1800, 6302, 6303, 6304, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 26.9% acid FI 2217 621 11.6% acid FI 2217 567 PBI/ Gordon Corporation 10.956% acid FI 2217 593 10% acid FI 2217 508 1.7% acid T 5481 144 Amvac Chemical Corporation See Amvac 94% IPE T for data requirements.

98% acid T ( r) 7969 171 BASF Corporation Repackaged  Data requirements will be satisfied by data for the source product 97% acid T ( r) 7969 174 Repackaged  Data requirements will be satisfied by data for the source product 99.3% acid T ( r) 34704 798 Platte Chemical Company, Inc. Repackaged  Data requirements will be satisfied by data for the source product 97% acid T 34704 797 Repackaged  Data requirements will be satisfied by data for the source product 95% acid T 35935 7 NuFarm Limited 830.1550, 1600, 1620, 1670, 1700, 1800, 6302, 6303, 6304, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 97.9% acid T 46146 3 Atanor S. A. 830.6317, 7050 97.9% acid T ( r) 48273 22 Marman USA, Inc. Repackaged  Data requirements will be satisfied by data for the source product;

however, the identity of the source product must be confirmed. Table 3 ( continued)

TGAI/ MP 1 EPA Reg. No. Registrant Outstanding OPPTS Guideline Requirements 2 15 ( continued; footnotes follow)

95% acid T 61272 5 NuFarm USA, Inc. 830.1700, 1750 95% acid T 61272 3 97.9% acid T 61469 2 Agro Gor Corporation 830.1600, 1620, 1670, 1700, 1800, 6302, 6303, 6304, 6314, 6315, 6316, 6317,

6319, 6320, 7000, 7100, 7300 97.9% acid T 61469 1 830.1620, 1670, 1700, 1800, 6302, 6303, 6304, 6314, 6315, 6316, 6317, 6319,

6320, 7000, 7100, 7300 97% acid T 62719 25 Dow AgroSciences LLC 830.6314, 7300 85% acid FI ( r) 62719 231 Repackaged  Data requirements will be satisfied by data for the source product.

74.8% acid T 62719 24 830.1700, 1750, 6317 99.3% acid T 72868 1 BASF Aktiengesellschaft Agricultural Center 830.6317, 6320 98.2% acid T ( r) 73754 1 GroWell Limited Repackaged  Data requirements will be satisfied by data for the source product 2,4 D sodium salt ( 030004)

90.6% Na T 228 123 NuFarm Americas, Inc. 830.6302, 6303, 6304, 6314, 7000, 7050, 7300, 7840 90.6% Na T ( r) 35935 19 NuFarm Limited Repackaged  Data requirements will be satisfied by data for the source product.

2,4 D diethanolamine salt ( 030016)

DEA TGAI N/ A PBI/ Gordon Corporation 830.1700, 7050 2,4 D dimethylamine salt ( 030019)

66.3% DMA FI 228 294 NuFarm Americas, Inc. 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 Table 3 ( continued)

TGAI/ MP 1 EPA Reg. No. Registrant Outstanding OPPTS Guideline Requirements 2 16 ( continued; footnotes follow)

31.8% DMA FI 239 2485 The Ortho Business Group 830.1550, 1600, 1650, 1670, 1700, 1750, 1800, 6302, 6303, 6304, 6313, 6314,

6315, 6316, 6317, 6319, 6320, 7000, 7100, 7200, 7220, 7300, 7370, 7550, 7840,

7950 66.57% DMA FI 2217 665 PBI/ Gordon Corporation 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 46.4% DMA FI 2217 654 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 61.37% DMA FI 35935 11 NuFarm Limited 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 66.18% DMA FI 61272 8 NuFarm USA, Inc. 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7100, 7300 67.1% DMA FI 62719 27 Dow AgroSciences LLC 830.1550, 1750, 7050 66.8% DMA FI 62719 52 830.1600, 1650, 1670, 1700, 1800, 6302, 6303, 6304, 6313, 6314, 6315, 6316,

6319, 7000, 7100, 7300 2,4 D isopropylamine salt ( 030025)

49.9% IPA T 62719 71 Dow AgroSciences LLC 830.7050 2,4 D triisopropanolamine salt ( 030035)

71% TIPA FI 62719 180 Dow AgroSciences LLC 830.6313, 7050, 7840, 7950 2,4 D 2 butoxyethyl ester ( 030053)

94% BEE T 228 136 NuFarm Americas, Inc. 830.1550, 1600, 1620, 1670, 1700, 1750, 1800, 6302, 6303, 6304, 6314, 6315,

6316, 6317, 6319, 6320, 7000, 7050, 7100, 7300, 7370 94.5% BEE T 62719 33 Dow AgroSciences LLC 830.1700, 7000, 7050, 7370 TGAI/ MP 1 EPA Reg. No. Registrant Outstanding OPPTS Guideline Requirements 2 17 2,4 D 2 ethylhexyl ester ( 030063)

93.3% 2 EHE T 2217 706 PBI/ Gordon Corporation 830.6314, 6315, 6316, 6317, 6319, 6320, 7050, 7100 94% 2 EHE T 35935 12 NuFarm Limited 830.1550, 1600, 1620, 1670, 1700, 1750, 1800, 6302, 6303, 6304, 6314, 6315,

6316, 6317, 6319, 6320, 7000, 7050, 7100, 7300 93.3% 2 EHE T 46146 5 Atanor S. A. Registration currently suspended; any further processing of applications is on hold until the registrations have been taken out of suspension.

830.1550, 1600, 1620, 1670, 1700, 1750, 6313, 6314, 6315, 6316, 6317, 6319,

6320, 7050, 7100, 7370, 7840 93.3% 2 EHE T 46146 4 98% 2 EHE T 61272 1 NuFarm USA, Inc. 830.1600, 1620, 1670, 1700, 1750, 1800, 6302, 6303, 6304, 6314, 6315, 6316,

6317, 6319, 6320, 7000, 7050, 7100, 7300 95% 2 EHE T 61272 7 830.1600, 1620, 1670, 1700, 1800, 6302, 6303, 6304, 6314, 6315, 6316, 6317,

6319, 6320, 7000, 7050, 7100, 7300 95.4% 2 EHE T 62719 26 Dow AgroSciences LLC 830.1550, 1750, 6319, 7050 93.3% 2 EHE T( r) 73754 2 GroWell Limited Repackaged  Data requirements will be satisfied by data for the source product 2,4 D isopropyl ester ( 030066)

95% IPE T 5481 144 Amvac Chemical Corporation 830.7050 94% IPE FI 35935 13 NuFarm Limited 830.1700, 7050 1 ( r) = Repackaged product.

2 Administrative revisions required for CSFs ( e. g., changes to update registrant or Reg. No. or corrections to nominal concentrations or certified limits) were not identified as data gaps and are detailed in the individual data summary tables. 18 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 97% acid T ( EPA Reg. No. 228 361)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 12/ 2/ 98 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 12/ 2/ 98 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. The NuFarm Americas 97% T is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the current registrant name, EPA Reg. No., and the nominal concentration and certified limits of the active ingredient in the product, based on the actual amount of active ingredient in the source product. 19 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 95% acid T ( EPA Reg. No. 228 360)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 11/ 10/ 98 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 11/ 10/ 98 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the current registrant name, EPA Reg. No., and the nominal concentration and certified limits of the active ingredient in the product, based on the actual amount of active ingredient in the source product. 20 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 95% acid T ( EPA Reg. No. 228 314)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF 4/ 4/ 96 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y CSF 4/ 4/ 96 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 21 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 98.2% acid T ( EPA Reg. No. 2217 455)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41219701 3, 41223801, 41926201 4, Letter 5/ 12/ 92 5, Letter 12/ 3/ 92 6, CSF 10/ 11/ 96 ( Alt. 1) 7, 44547901 8, CSF 9/ 23/ 99 ( Alt. 2) 9 CSF 9/ 23/ 99 ( Alt. 3) 10 830.1600 Description of materials used to produce the product Y 41223801, 41637501 11, 41790601 12, 44149301 7, 44547901 8 830.1620 Description of production process Y 41223801, 41790601 12, 44149301 7, 44547901 8 830.1670 Discussion of formation of impurities Y 41223801, 41790601 12, 44149301 7, 44547901 8 830.1700 Preliminary analysis Y 41219701 3, 41926201 4, 41790602 13, 44149302 7, 44543502 8, 44543503 8, 44932701 9 830.1750 Certified limits Y 41219701 3, 41223801, 41926201 4, Letter 5/ 12/ 92 5, Letter 12/ 3/ 92 6, CSF 10/ 11/ 96 ( Alt. 1) 7, CSF 9/ 23/ 99 ( Alt. 2) 9 CSF 9/ 23/ 99 ( Alt. 3) 10 830.1800 Enforcement analytical method Y 41219701 3, 41223801, 41637501 11, 41926201 4 44543502 8, 44543503 8 830.6302 Color Y 41223801, 44543504 8 830.6303 Physical state Y 41223801, 44543504 8 830.6304 Odor Y 41223801, 44543504 8 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41223801, 41745301 11, 42023601 14, 44543504 8 830.6314 Oxidation/ reduction: chemical incompatibility Y 42023601 14, Letter 12/ 3/ 92 6 830.6315 Flammability N/ A 15 830.6316 Explodability Y 41745302 11 830.6317 Storage stability Y 41745301 11, 41926203 4 830.6319 Miscibility N/ A 15 830.6320 Corrosion characteristics Y 42023601 14 830.7000 pH Y 41926202 4, 44543504 8 830.7050 UV/ Visible absorption Y 44543504 8 Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 22 830.7100 Viscosity N/ A 15 830.7200 Melting point/ melting range Y 41223801, 44543504 8 830.7220 Boiling point/ boiling range N/ A 15 830.7300 Density/ relative density/ bulk density Y 41223801, 44543504 8 830.7370 Dissociation constants in water Y 41223801, 41308901 16, 41972501 6, 44543504 8 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41332004 16, 44543504 8 830.7840 Water solubility: column elution method; shake flask method Y 41223801, 42023601 14, 41332002 6, 44543504 8, 45692501 17 830.7950 Vapor pressure Y 41223801, 44543504 8 1 Y = Yes; N = No; N/ A = Not Applicable. There is a basic and two alternate formulations of the PBI/ Gordon 98.2% T; the two alternate formulations have similar purity and impurity profiles of the basic formulation and are acceptable as alternate formulations. 2 Bolded references were reviewed under CB No. 6393, 4/ 3/ 90, G. Makhijani and under CB No. 7138, 11/ 16/ 90, S. Funk for dioxins ( GLNs 830. 1600, 1620, and 1670); and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 3 CB No. 5763, 2/ 15/ 90, F. Griffith. 4 D167302, 9/ 25/ 91, R. Perfetti. 5 D180997, 8/ 11/ 92, S. Funk. 6 D186542 and D190622, 6/ 1/ 93, W. Smith. 7 RD Memorandum, D231434, 12/ 11/ 96, A. Smith for Alternate # 1. 8 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur for Alternate # 2. 9 RD Memorandum, D267474, 8/ 9/ 00, B. Kitchens. 10 CSF obtained from the product jacket, accepted 10/ 19/ 99. 11 D161036, 4/ 30/ 91, R. Perfetti. 12 D172810, 1/ 28/ 92, S. Funk. 13 D162524, 11/ 26/ 91, S. Funk. 14 D170803, 7/ 16/ 92, E. Zager. 15 Data are not required because the T/ TGAI is a solid at room temperature. 16 D169647, 6/ 30/ 92, S. Funk. 17 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 23 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 37.6% acid FI ( EPA Reg. No. 2217 615)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 8/ 14/ 98 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 8/ 14/ 98 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is formulated from EPA registered products; TGAI/ PAI data requirements will be satisfied by data for the technical source products. 2 The CSF was obtained from the product jacket and was accepted 9/ 10/ 98 by S. Stanton. 3 Because of differing active ingredient levels in the listed source products, basic and alternate formulation CSFs are required for this product. 24 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 26.9% acid FI ( EPA Reg. No. 2217 621)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 8/ 14/ 98 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 8/ 14/ 98 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is formulated from EPA registered products; TGAI/ PAI data requirements will be satisfied by data for the technical source products. 2 The CSF was obtained from the product jacket and was accepted 9/ 11/ 98 by S. Stanton. 3 Because of differing active ingredient levels in the listed source products, basic and alternate formulation CSFs are required for this product. 25 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 11.6% acid FI ( EPA Reg. No. 2217 567)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 7/ 23/ 98 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 7/ 23/ 98 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is formulated from EPA registered products; TGAI/ PAI data requirements will be satisfied by data for the technical source products. 2 The CSF was obtained from the product jacket and was reviewed under RD memorandum D249891, 10/ 19/ 98, S. Malak. 3 Because of differing active ingredient levels in the listed source products, basic and alternate formulation CSFs are required for this product. 26 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 10.956% acid FI ( EPA Reg. No. 2217 593)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 8/ 14/ 98 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 8/ 14/ 98 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is formulated from EPA registered products; TGAI/ PAI data requirements will be satisfied by data for the technical source products. 2 The CSF was obtained from the product jacket and was reviewed under RD memorandum D236698, 7/ 29/ 97, B. Kitchens. 3 Because of differing active ingredient levels in the listed source products, basic and alternate formulation CSFs are required for this product. 27 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 10% acid FI ( EPA Reg. No. 2217 508)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 5/ 5/ 97 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 5/ 5/ 97 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is formulated from EPA registered products; TGAI/ PAI data requirements will be satisfied by data for the technical source products. 2 The CSF was obtained from the product jacket and was reviewed under RD memorandum D236701, 7/ 29/ 97, B. Kitchens. 3 Because of differing active ingredient levels in the listed source products, basic and alternate formulation CSFs are required for this product. 28 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: BASF Corporation Product( s): 98% acid T ( EPA Reg. No. 7969 171)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF 8/ 19/ 98 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y CSF 8/ 19/ 98 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from the alternate source of another EPAregistered 2,4 D acid product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 29 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: BASF Corporation Product( s): 97% acid T ( EPA Reg. No. 7969 174)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 12/ 20/ 98 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 12/ 20/ 98 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the nominal concentration and certified limits of the active ingredient in the product, based on the actual amount of active ingredient in the source product. 30 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Platte Chemical Company, Inc. Product( s): 99.3% acid T ( EPA Reg. No. 34704 798)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 2/ 20/ 97 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 2/ 20/ 97 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 3 The source product listed on the CSF has been transferred. An updated CSF must be submitted reflecting the current supplier and EPA Reg. No. of the source product. 31 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Platte Chemical Company, Inc. Product( s): 97% acid T ( EPA Reg. No. 34704 797)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF 2/ 20/ 97 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y CSF 2/ 20/ 97 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 32 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: NuFarm Limited Product( s): 95% acid T ( EPA Reg. No. 35935 7)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 12/ 20/ 88 830.1600 Description of materials used to produce the product N 830.1620 Description of production process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y CSF 12/ 20/ 88 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41055803 4, 41855701 5, 42023601 6, 42795401 7 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption Y 44543504 8 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 41055803 4, 41067001 9, 41223801 10 830.7220 Boiling point/ boiling range N/ A 11 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water Y 41055803 4, 41067001 9, 41972501 12, 44543504 8 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41332004 13 830.7840 Water solubility: column elution method; shake flask method Y 41055803 4, 45692501 14 830.7950 Vapor pressure Y 41055803 4, 41067001 9, 44543504 8 1 Y = Yes; N = No; N/ A = Not Applicable. This product was transferred from Agrolinz, Inc. ( EPA Reg. No. 42545 8). 2 The CSF was reviewed under RD Memorandum D177498, 5/ 22/ 92, A. Skapars; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 3 The label claim is not in agreement with the nominal concentration of the active ingredient; a revised CSF and/ or label must be submitted. In addition, the CSF must be revised to reflect the current registrant and EPA Reg. No. 33 4 CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 5 Letter dated 12/ 2/ 91 from L. Rossi ( SRRD) to K. Shearer of Rhone Poulenc ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 6 D170803, 7/ 16/ 92, E. Zager ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 7 D192560, 8/ 5/ 93, F. Toghrol ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 8 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 9 CB 5549, 9/ 26/ 89, M. Nelson ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 10 CB 6393, 4/ 3/ 90, G. Makhijani ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 11 Data are not required because the TGAI is a solid at room temperature. 12 D186542 and D190622, 6/ 1/ 93, W. Smith ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 13 CB 6581, 7/ 27/ 90, G. Makhijani ( Task Force PAI data). 14 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 34 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Atanor S. A. Product( s): 97.9% acid T ( EPA Reg. No. 46146 3)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 43516401, 43516402, 43981801 3, CSF 2/ 16/ 99 4 830.1600 Description of materials used to produce the product Y 43516401 5 830.1620 Description of production process Y 43516401 5 830.1670 Discussion of formation of impurities Y 43516401 5 830.1700 Preliminary analysis Y 43516401, 43516402, 43981801 3, Report 6 830.1750 Certified limits Y 43516401, 43516402, 43981801 3, CSF 2/ 16/ 99 4 830.1800 Enforcement analytical method Y 43516401, 43516402, 43981801 3, Report 6 830.6302 Color Y 43516403 5, 43516404 5 830.6303 Physical state Y 43516403 5, 43516404 5 830.6304 Odor Y 43516403 5, 43516404 5 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 43516403 5, 43516404 5 830.6314 Oxidation/ reduction: chemical incompatibility Y 43516403 5, 43516404 5 830.6315 Flammability N/ A 7 830.6316 Explodability Y 43516403 5, 43516404 5 830.6317 Storage stability N 8 43516403 5, 43516404 5 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics Y 43516403 5, 43516404 5 830.7000 pH Y 43516403 5, 43516404 5 830.7050 UV/ Visible absorption N 9 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range Y 43516403 5, 43516404 5 830.7220 Boiling point/ boiling range N/ A 7 830.7300 Density/ relative density/ bulk density Y 43516403 5, 43516404 5 830.7370 Dissociation constants in water Y 43516403 5, 43516404 5 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 43516403 5, 43516404 5 830.7840 Water solubility: column elution method; shake flask method Y 43516403 5, 43516404 5 830.7950 Vapor pressure Y 43516403 5, 43516404 5 1 Y = Yes; N = No; N/ A = Not Applicable. This product was transferred from R. A. M. Research, Inc. ( EPA Reg. No. 69474 1); based on the CSFs, the producer did not change with the product transfer. 2 Bolded references were reviewed under D215421, 6/ 8/ 95, S. Funk for dioxins and under Registration Memorandum, D211526, 2/ 13/ 95, A. Smith, for other reregistration requirements; and all other references were reviewed as noted. 35 3 D226030, 9/ 9/ 96, S. Funk. 4 Letter dated 7/ 23/ 99 from J. Miller ( Registration Division) to E. Finkel ( R. A. M. Research, Inc.). We note that the CSF should be updated to reflect the current registrant name. 5 Registration Memorandum, D211526, 2/ 13/ 95, A. Smith. 6 D232535 and D232688, 2/ 20/ 97, S. Funk. 7 Data are not required because the T/ TGAI is a solid at room temperature. 8 Although storage stability data were determined to be satisfied under the RD Memorandum, data are required demonstrating the stability of the product in the typical container for one year at ambient conditions. 9 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI. 36 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Marman USA, Inc. Product( s): 97.9% acid T ( EPA Reg. No. 48273 22)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 9/ 17/ 96 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 9/ 17/ 96 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product, provided the registrant confirms the identity of the source product. The product jacket contains a letter dated 7/ 20/ 98 from the Registration Division to the Policy Enforcement Branch which indicates that the registrant of the listed source product has stated that they have never supplied their registered product to Marman USA. The identity of the source product must be confirmed. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised so that the name listed in Box 2 is the name of the producer of the source product and not the registrant of the repackaged product. 37 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: NuFarm USA, Inc. Product( s): 95% acid Ts ( EPA Reg. Nos. 61272 3 and 61272 5)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 40808301 830.1600 Description of materials used to produce the product Y 40808301 830.1620 Description of production process Y 40808301 830.1670 Discussion of formation of impurities Y 40808301 830.1700 Preliminary analysis N 3 40808301, 41724201 4, 41724202 4, 41349001 5 830.1750 Certified limits N 6 40808301 830.1800 Enforcement analytical method Y 40808301 830.6302 Color Y 40808301 830.6303 Physical state Y 40808301 830.6304 Odor Y 40808301 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 40808301 830.6314 Oxidation/ reduction: chemical incompatibility Y 40808301 830.6315 Flammability N/ A 7 830.6316 Explodability Y 40808301 830.6317 Storage stability Y 40808301 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics Y 40808301 830.7000 pH Y 40808301 830.7050 UV/ Visible absorption Y 44543504 8 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range Y 40808301 830.7220 Boiling point/ boiling range N/ A 7 830.7300 Density/ relative density/ bulk density Y 40808301 830.7370 Dissociation constants in water Y 40808301 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 40808301 830.7840 Water solubility: column elution method; shake flask method Y 40808301, 45692501 9 830.7950 Vapor pressure Y 40808301 1 Y = Yes; N = No; N/ A = Not Applicable. Based on RD Memoranda dated 5/ 12/ 93, L. Markman and 11/ 7/ 93, I. Blackwell, these products are identical; the submitted data are applicable to both products. 2 Bolded references were reviewed under Registration Division Memorandum, 6/ 5/ 92, A. Smith which stated " the referenced MRID satisfies the requirements of 40 CFR 158.150 158.190. The product chemistry requirements are satisfied for this product." No data were presented in the review. All other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 38 3 Additional information concerning the sampling dates and method are required concerning the preliminary analysis for dioxins. 4 D160163, 11/ 26/ 91, S. Funk for dioxins. 5 CB No. 6295, 5/ 24/ 90, S. Funk. 6 A revised CSF must be submitted to incorporate the results of the dioxin analyses; upper certified limits must be proposed for those dioxin or dibenzofuran compounds present at greater than the respective EPA LOQs. 7 Data are not required because the T/ TGAI is a solid at room temperature. 8 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 9 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 39 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Agro Gor Corporation Product( s): 97.9% acid T ( EPA Reg. No. 61469 2)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 12/ 15/ 93 830.1600 Description of materials used to produce the product N 830.1620 Description of production process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 4 41796201 5, 41796202 5 830.1750 Certified limits Y 3 CSF 12/ 15/ 93 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41055803 6, 41855701 7, 420236018, 42795401 9 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption Y 44543504 10 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 41055803 6, 41067001 11, 41223801 12 830.7220 Boiling point/ boiling range N/ A 13 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water Y 41055803 6, 41067001 11, 41972501 14, 44543504 10 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41332004 15 830.7840 Water solubility: column elution method; shake flask method Y 41055803 6, 45692501 16 830.7950 Vapor pressure Y 41055803 6, 41067001 11, 44543504 10 1 Y = Yes; N = No; N/ A = Not Applicable. This product was transferred from Agrolinz ( EPA Reg. No. 42545 30); data requirements are based on data submitted by Agrolinz. 2 The referenced CSF was reviewed under CB No. 13060, D198004, 8/ 23/ 94, L. Cheng; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 3 The CSF must be resubmitted to properly identify the registrant and EPA Registry number since the product transfer. 40 4 Adequate dioxin analysis data have been submitted; however, preliminary analysis of five batches of the technical product for all components present at

0.1% in the TGAI must be submitted. 5 Data reviewed under CB No. 7737, 11/ 26/ 91, S. Funk for EPA Reg. No. 61469 1; S. Funk determined ( D189025, 6/ 25/ 93) that the data may be translated to this product. 6 CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 7 Letter dated 12/ 2/ 91 from L. Rossi ( SRRD) to K. Shearer of Rhone Poulenc ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 8 D170803, 7/ 16/ 92, E. Zager ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 9 D192560, 8/ 5/ 93, F. Toghrol ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 10 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 11 CB 5549, 9/ 26/ 89, M. Nelson ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 12 CB 6393, 4/ 3/ 90, G. Makhijani ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 13 Data are not required because the TGAI is a solid at room temperature. 14 D186542 and D190622, 6/ 1/ 93, W. Smith ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 15 CB 6581, 7/ 27/ 90, G. Makhijani ( Task Force PAI data). 16 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 41 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Agro Gor Corporation Product( s): 97.9% acid T ( EPA Reg. No. 61469 1)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41219601 3, CSF 2/ 15/ 91 830.1600 Description of materials used to produce the product Y 41246701 4, 41681901, 41796201 830.1620 Description of production process N 5 41246701 4, 41796201 830.1670 Discussion of formation of impurities N 6 41246701 4 830.1700 Preliminary analysis N 7 41219601 3, 41796202 830.1750 Certified limits Y 41219601 3, CSF 2/ 15/ 91 830.1800 Enforcement analytical method N 8 41219601 3, 41796202 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41055803 9, 41855701 10, 4202360111, 42795401 12 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption Y 44543504 13 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 41055803 9, 41067001 14, 41223801 15 830.7220 Boiling point/ boiling range N/ A 16 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water Y 41055803 9, 41067001 14, 41972501 17, 44543504 13 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41332004 18 830.7840 Water solubility: column elution method; shake flask method Y 41055803 9, 45692501 19 830.7950 Vapor pressure Y 41055803 9, 41067001 14, 44543504 13 1 Y = Yes; N = No; N/ A = Not Applicable. 2 The bolded references were reviewed under D162358, 11/ 26/ 91, S. Funk; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 42 3 CB No. 5860, 2/ 8/ 90, F. Griffith. 4 CB No. 7137, 11/ 16/ 90, S. Funk. 5 Additional information concerning whether the production equipment is used to produce other products is required. 6 An adequate discussion has been submitted for the possible formation of dioxins/ dibenzofurans; however, a discussion is required concerning the formation of other impurities listed on the CSF, and the potential for formation of impurities resulting from post production reactions and cross contamination from use of equipment for other products. 7 Adequate dioxin analyses have been submitted; however, preliminary analysis of five batches of the technical product for all components present at

0.1% in the TGAI must be submitted. 8 Adequate enforcement methods have been submitted for dioxins/ dibenzofurans; however, enforcement analytical methods with supporting validation data are required for all other components present in the final product and for which upper certified limits have been proposed ( active ingredients and impurities present at

0.1% or of toxicological significance). 9 CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 10 Letter dated 12/ 2/ 91 from L. Rossi ( SRRD) to K. Shearer of Rhone Poulenc ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 11 D170803, 7/ 16/ 92, E. Zager ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 12 D192560, 8/ 5/ 93, F. Toghrol ( TGAI data for the Dow AgroSciences 97% acid T, EPA Reg. No. 62719 25). 13 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 14 CB 5549, 9/ 26/ 89, M. Nelson ( TGAI data for the BASF 99.3% acid T, EPA Reg. No. 72868 1). 15 CB 6393, 4/ 3/ 90, G. Makhijani ( TGAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 16 Data are not required because the TGAI is a solid at room temperature. 17 D186542 and D190622, 6/ 1/ 93, W. Smith ( PAI data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 18 CB 6581, 7/ 27/ 90, G. Makhijani ( Task Force PAI data). 19 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 43 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 97% acid " flake" T ( EPA Reg. No. 62719 25)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41055804, 41055805, 41220101 3, 41973501 4, CSF 2/ 6/ 01 5 830.1600 Description of materials used to produce the product Y 41055804, 41496701 6 830.1620 Description of production process Y 41055801, 41496701 6 830.1670 Discussion of formation of impurities Y 41973501 4 830.1700 Preliminary analysis Y 7 41055805, 41220101 3, 41496701 6, 41973501 4, 43777501 8, 44287101 9 830.1750 Certified limits Y 41055804, 41055805, 41220101 3, 41496701 6, 41973501 4, CSF 2/ 6/ 01 5 830.1800 Enforcement analytical method Y 41055802, 41220101 3, 41496701 6 830.6302 Color Y 41055803 830.6303 Physical state Y 41055803 830.6304 Odor Y 41055803 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41055803, 42795401 10 830.6314 Oxidation/ reduction: chemical incompatibility N 11 830.6315 Flammability N/ A 12 830.6316 Explodability Y 41973501 4 830.6317 Storage stability Y 43260501 13 830.6319 Miscibility N/ A 12 830.6320 Corrosion characteristics Y 43260501 13 830.7000 pH N/ A 14 830.7050 UV/ Visible absorption Y 44543504 15 830.7100 Viscosity N/ A 12 830.7200 Melting point/ melting range Y 41055803 830.7220 Boiling point/ boiling range N/ A 12 830.7300 Density/ relative density/ bulk density N 11, 16 41055803 830.7370 Dissociation constants in water Y 41055803 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41055803 830.7840 Water solubility: column elution method; shake flask method Y 41055803, 45692501 17 830.7950 Vapor pressure Y 41055803 1 Y = Yes; N = No; N/ A = Not Applicable. 44 2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 3 CB No. 5826, 2/ 13/ 90, F. Griffith. 4 D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol. 5 RD Memorandum, D273235, 4/ 2/ 01, S. Mathur. 6 CB No. 6776, 8/ 7/ 90, S. Funk. 7 The available dioxin data are acceptable pending receipt of additional sampling information. 8 D219403, 1/ 3/ 97, D. Miller. 9 D236419. 10 D192560, 8/ 5/ 93, F. Toghrol. 11 The registrant must indicate whether data submitted under D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol for the " molten" acid ( EPA Reg. No. 62719 25) are applicable to the " flake" acid. 12 Data are not required because the T/ TGAI is a solid at room temperature. 13 D204466, 9/ 15/ 94, F. Toghrol. 14 Data are not applicable because the T/ TGAI is not dispersible in water. 15 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% T, EPA Reg. No. 2217 455). 16 Data demonstrating the specific gravity at 20 25 C are required. 17 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 45 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 85% acid FI ( EPA Reg. No. 62719 231)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 3/ 17/ 92 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits N 3 CSF 3/ 17/ 92 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. According to the CSF, the Dow AgroSciences 85% T is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. We note that the source product has apparently been canceled; if the 85% T is no longer repackaged from an EPA registered product, all product chemistry data will be required. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the current technical source product; the listed source product has been canceled. 46 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 74.8% acid " molten" T ( EPA Reg. No. 62719 24)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41055801, 41055802, 41220101 3, 41973501 4, CSF 12/ 22/ 98 5 830.1600 Description of materials used to produce the product Y 41055801, 41496701 6, 41973501 4 830.1620 Description of production process Y 41055801, 41496701 6, 41973501 4 830.1670 Discussion of formation of impurities Y 41055801, 41973501 4 830.1700 Preliminary analysis N 7 41055802, 41220101 3, 41496701 6, 41973501 4, 43777502 8, 44228601 5 830.1750 Certified limits N 9 41055801, 41055802, 41220101 3, 41496701 6, 41973501 4, CSF 12/ 22/ 98 5 830.1800 Enforcement analytical method Y 41055802, 41220101 3, 41496701 6 830.6302 Color Y 41055803 830.6303 Physical state Y 41055803 830.6304 Odor Y 41055803 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41055803, 41973502 4 830.6314 Oxidation/ reduction: chemical incompatibility Y 41973501 4 830.6315 Flammability N/ A 10 830.6316 Explodability Y 41973501 4 830.6317 Storage stability N 11 830.6319 Miscibility N/ A 10 830.6320 Corrosion characteristics Y 41973501 4 830.7000 pH N/ A 12 830.7050 UV/ Visible absorption Y 44543504 13 830.7100 Viscosity N/ A 10 830.7200 Melting point/ melting range Y 41055803 830.7220 Boiling point/ boiling range N/ A 10 830.7300 Density/ relative density/ bulk density Y 41055803, 41973501 4 830.7370 Dissociation constants in water Y 41055803 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41055803 830.7840 Water solubility: column elution method; shake flask method Y 41055803, 45692501 14 830.7950 Vapor pressure Y 41055803 47 1 Y = Yes; N = No; N/ A = Not Applicable.

2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 CB No. 5826, 2/ 13/ 90, F. Griffith.

4 D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol.

5 Registration Memorandum, D252258, 2/ 2/ 99, H. Podall.

6 CB No. 6776, 8/ 7/ 90, S. Funk.

7 Values given for the amount of an impurity present in the product and reported on the CSF were not included in the preliminary analysis report. This should be corrected for the record.

8 D219403, 1/ 3/ 97, D. Miller.

9 The range of certified limits proposed for the active ingredient is wider than required under 40 CFR 158.175( b)( 2) and seems excessive for the variations resulting from the process conditions.

10 Data are not required because the T/ TGAI is a solid at room temperature.

11 Study in progress per D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol.

12 Data are not applicable because the T/ TGAI is not dispersible in water.

13 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% T, EPA Reg. No. 2217 455).

14 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 48 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: BASF Aktiengesellschaft Product( s): 99.3% acid T ( EPA Reg. No. 72868 1)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41067001, 41203301 3, CSF 12/ 16/ 92 4 830.1600 Description of materials used to produce the product Y 41067001, 41599401 5 830.1620 Description of production process Y 41067001, 41599401 5, 41789901 6 830.1670 Discussion of formation of impurities Y 41067001, 41599401 5, 41789901 6, 41789902 6 830.1700 Preliminary analysis Y 41067001, 41203301 7, 41735701 8 830.1750 Certified limits Y 41067001, 41203301 3, 41599401 5, CSF 12/ 16/ 92 4 830.1800 Enforcement analytical method Y 41067001, 41203301 3, 41599401 5, 41789902 6 830.6302 Color Y 41067001 830.6303 Physical state Y 41067001 830.6304 Odor Y 41067001 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41067001, 41855701 9 830.6314 Oxidation/ reduction: chemical incompatibility Y 41067001 830.6315 Flammability N/ A 10 830.6316 Explodability N/ A 11 41067001 830.6317 Storage stability N 12 41067001 830.6319 Miscibility N/ A 10 830.6320 Corrosion characteristics N 12 41067001 830.7000 pH N/ A 13 830.7050 UV/ Visible absorption Y 44543504 14 830.7100 Viscosity N/ A 10 830.7200 Melting point/ melting range Y 41067001 830.7220 Boiling point/ boiling range N/ A 10 830.7300 Density/ relative density/ bulk density Y 41067001, 41855701 9 830.7370 Dissociation constants in water Y 41067001 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41067001 830.7840 Water solubility: column elution method; shake flask method Y 41067001, 41332002 6, 41880601 9, 45692501 14 830.7950 Vapor pressure Y 41067001 1 Y = Yes; N = No; N/ A = Not Applicable. This product was transferred from Rhone Poulenc ( EPA Reg. No. 264 492). BASF must confirm that the manufacturing location and process have not changed since the product transfer, otherwise additional product chemistry data may be required. 49 2 Bolded references were reviewed under CB No. 5549, 9/ 26/ 89, M. Nelson; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 CB No. 5750, 2/ 8/ 90, F. Griffith.

4 D189458, 8/ 12/ 93, M. Clifford.

5 CB No. 7139, 11/ 13/ 90, S. Funk.

6 D162701, 7/ 31/ 91, S. Funk.

7 CB No. 6584, 7/ 12/ 90, S. Funk.

8 D160520, 7/ 24/ 91, S. Funk.

9 Letter dated 12/ 2/ 91 from L. Rossi ( SRRD) to K. Shearer ( Rhone Poulenc) states data requirements are satisfied for this guideline; the actual review was not available.

10 Data are not required because the T/ TGAI is a solid at room temperature.

11 Data are not required because the MP does not contain explosive ingredients.

12 Quantitative data and methods are required.

13 Data are not applicable because the TGAI is not dispersible in water.

14 RD Memorandum, D245940, 6/ 9/ 98, S. Mathur ( PAI data for the PBI/ Gordon 98.2% T, EPA Reg. No. 2217 455).

15 D283959, 3/ 1/ 04, W. Hazel ( revised water solubility data for the Task Force PAI). 50 Case No. 0073 Chemical No. 030001 Case Name: 2,4 D Registrant: GroWell Limited Product( s): 98.2% acid T ( EPA Reg. No. 73754 1)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 8/ 3/ 01 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 8/ 3/ 01 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. This product is repackaged from an EPA registered product; all product chemistry data requirements will be fulfilled by data for the source product. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the nominal concentration and certified limits of the active ingredient in the product, based on the actual amount of active ingredient in the source product. 51 Case No. 0073 Chemical No. 030004 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 90.6% Na T ( EPA Reg. No. 228 123)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41123601, Letter 4/ 12/ 94 3 830.1600 Description of materials used to produce the product Y 42537501 4, Letter 4/ 12/ 94 3 830.1620 Description of production process Y 42537501 4 830.1670 Discussion of formation of impurities Y 41123601, 42537501 4 830.1700 Preliminary analysis Y 41123601, Letter 4/ 12/ 94 3 830.1750 Certified limits Y 5 41123601, Letter 4/ 12/ 94 3 830.1800 Enforcement analytical method Y 41123601, 42537501 4 830.6302 Color N 6 41123601 830.6303 Physical state N 6 41123601 830.6304 Odor N 6 41123601 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N/ A 7 830.6316 Explodability Y 8 42537501 4 830.6317 Storage stability Y 41123601, 42227501 9 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics Y 41123601, 42227501 9 830.7000 pH N 6 41123601 830.7050 UV/ Visible absorption N 10 830.7100 Viscosity N/ A 7 830.7200 Melting point/ melting range Y 42537501 4 830.7220 Boiling point/ boiling range N/ A 7 830.7300 Density/ relative density/ bulk density N 6 41123601 830.7370 Dissociation constants in water N/ A 11 41972501 12 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 8 42537501 4 830.7840 Water solubility: column elution method; shake flask method N 13 42537501 4 830.7950 Vapor pressure Y 8 42537501 4 1 Y = Yes; N = No; N/ A = Not Applicable.

2 Bolded references were reviewed under CB No. 7945, 6/ 1/ 92; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 D203749, 10/ 6/ 94, F. Toghrol.

4 D184583, 2/ 8/ 93, F. Toghrol. 52 5 Pending decision by SRRD/ RD as to whether upper certified limits are required for the sodium salt impurities.

6 The test substance used for the determinations must be identified.

7 Data are not required because the TGAI/ MP is a solid at room temperature.

8 Data requirements were waived under D184583, 2/ 8/ 93, F. Toghrol.

9 D175577.

10 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

11 Data are not required because the Na salt completely dissociates in aqueous solutions; this data requirement will be fulfilled by data for the acid source product.

12 D186542 and D190622, W. Smith ( conductance data for the Na salt included with data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455).

13 Additional data are required concerning the solvents used, temperatures of the study, test substance identification, and the experimental conditions. 53 Case No. 0073 Chemical No. 030004 Case Name: 2,4 D Registrant: NuFarm Limited Product( s): 90.6% Na T ( EPA Reg. No. 35935 19)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 5/ 7/ 96 830.1600 Description of materials used to produce the product N/ A 830.1620 Description of production process N/ A 830.1670 Discussion of formation of impurities N/ A 830.1700 Preliminary analysis N/ A 830.1750 Certified limits Y 3 CSF 5/ 7/ 96 830.1800 Enforcement analytical method N/ A 830.6302 Color N/ A 830.6303 Physical state N/ A 830.6304 Odor N/ A 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N/ A 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 830.6315 Flammability N/ A 830.6316 Explodability N/ A 830.6317 Storage stability N/ A 830.6319 Miscibility N/ A 830.6320 Corrosion characteristics N/ A 830.7000 pH N/ A 830.7050 UV/ Visible absorption N/ A 830.7100 Viscosity N/ A 830.7200 Melting point/ melting range N/ A 830.7220 Boiling point/ boiling range N/ A 830.7300 Density/ relative density/ bulk density N/ A 830.7370 Dissociation constants in water N/ A 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 830.7840 Water solubility: column elution method; shake flask method N/ A 830.7950 Vapor pressure N/ A 1 Y = Yes; N = No; N/ A = Not Applicable. According to the CSF, the 90.6% T is repackaged from an EPAregistered product; therefore, all product chemistry data requirements will be fulfilled by data for the source product. However, the NuFarm 90.6% Na T was transferred from Riverdale Chemical Company ( EPA Reg. No. 228 319), and NuFarm must confirm that the source product has not changed since the product transfer; otherwise, additional product chemistry data may be required. 2 The CSF was obtained from the product jacket. 3 The CSF must be revised to reflect the current registrant name, EPA Reg. No., and the nominal concentration and certified limits of the active ingredient in the product, based on the actual amount of active ingredient in the source product. 54 Case No. 0073 Chemical No. 030016 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 2,4 D Diethanolamine ( DEA) TGAI PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N/ A 3 830.1600 Description of materials used to produce the product Y 44184201 4 830.1620 Description of production process Y 44184201 4 830.1670 Discussion of formation of impurities Y 44184201 4 830.1700 Preliminary analysis N 830.1750 Certified limits N/ A 3 830.1800 Enforcement analytical method N/ A 3 830.6302 Color Y 42857203 830.6303 Physical state Y 42857203 830.6304 Odor Y 42857203 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 42857209 830.6314 Oxidation/ reduction: chemical incompatibility N/ A 3 830.6315 Flammability N/ A 3 830.6316 Explodability N/ A 3 830.6317 Storage stability N/ A 3 830.6319 Miscibility N/ A 3 830.6320 Corrosion characteristics N/ A 3 830.7000 pH Y 42857208 830.7050 UV/ Visible absorption N 830.7100 Viscosity N/ A 3 830.7200 Melting point/ melting range Y 42857209 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density Y 42857204 830.7370 Dissociation constants in water N/ A 6 41972501 7 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 42857207 830.7840 Water solubility: column elution method; shake flask method Y 42857205 830.7950 Vapor pressure Y 42857206 1 Y = Yes; N = No; N/ A = Not Applicable. 2,4 D DEA TGAI data are required to support the PBI/ Gordon EPs ( EPA Reg. Nos. 2217 703, 2217 807, and 2217 813) manufactured by an integrated system from 2,4 D acid.

2 Bolded references were reviewed under D194119, 1/ 31/ 94, F. Toghrol; and all other references were reviewed as noted. 55 3 Product specific data are not required for the TGAI.

4 RD Memorandum, D232536, 6/ 27/ 97, A. Smith; data submitted for the EP will also satisfy the TGAI data requirement.

5 Data are not required because the TGAI is a solid at room temperature.

6 Data are not required because the DEA salt completely dissociates in aqueous solutions; this data requirement will be fulfilled by data for the acid source product( s).

7 D186542 and D190622, W. Smith ( conductance data for the DEA salt included with data for the PBI/ Gordon 98.2% acid T, EPA Reg. No. 2217 455). 56 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 66.3% DMA FI ( EPA Reg. No. 228 294)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSFs 1/ 5/ 81 and 1/ 22/ 82 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y 3 CSFs 1/ 5/ 81 and 1/ 22/ 82 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 4 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 6 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 7 830.7840 Water solubility: column elution method; shake flask method Y 43358801 8 830.7950 Vapor pressure Y 42021001 9 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product. 2 CSFs for alternate formulations were obtained from the product jacket; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 3 The CSFs must be modified to reflect the current registrant, EPA Reg. No., and source products. 4 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 5 Data are not required because the PAI is a solid at room temperature. 57 6 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 7 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 8 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 9 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 58 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: The Ortho Business Group Product( s): 31.8% DMA FI ( EPA Reg. No. 239 2485)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSFs 1/ 27/ 95 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits N 3 CSFs 1/ 27/ 95 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range N 830.7220 Boiling point/ boiling range N 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N 830.7550 Partition coefficient ( n octanol/ water), shake flask method N 830.7840 Water solubility: column elution method; shake flask method N 830.7950 Vapor pressure N 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product. 2 The CSF was reviewed under Registration Division memorandum D214918, 6/ 26/ 95, T. Alston. 3 The CSF must be modified to include the DMA salt and its acid equivalent. 59 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 66.57% DMA FI ( EPA Reg. No. 2217 665)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSFs 12/ 15/ 95 3 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y CSFs 12/ 15/ 95 3 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 4 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 6 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 7 830.7840 Water solubility: column elution method; shake flask method Y 43358801 8 830.7950 Vapor pressure Y 42021001 9 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 The CSFs for alternate formulations were obtained from the product jacket; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 60 3 The CSFs for a basic and three alternate formulations of the 66.57% FI were reviewed under Registration Division memorandum D224080, 4/ 10/ 96, T. Alston.

4 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

5 Data are not required because the PAI is a solid at room temperature.

6 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

7 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

8 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

9 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 61 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 46.4% DMA FI ( EPA Reg. No. 2217 654)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 8/ 25/ 81 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y 3 CSF 8/ 25/ 81 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 4 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 6 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 7 830.7840 Water solubility: column elution method; shake flask method Y 43358801 8 830.7950 Vapor pressure Y 42021001 9 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 The CSF obtained from the product jacket was reviewed by the Registration Division under D224080, 4/ 10/ 96, T. Alston; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 62 3 The CSF must be modified to reflect the current registrant, EPA Reg. No., and sources.

4 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

5 Data are not required because the PAI is a solid at room temperature.

6 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

7 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

8 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

9 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 63 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: NuFarm Limited Product( s): 61.37% DMA FI ( EPA Reg. No. 35935 11)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 3 CSF 11/ 6/ 79 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y 3 CSF 11/ 6/ 79 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 4 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 6 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 7 830.7840 Water solubility: column elution method; shake flask method Y 43358801 8 830.7950 Vapor pressure Y 42021001 9 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 The CSF was obtained from the product jacket; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 The CSF must be modified to reflect the current registrant, EPA Reg. No., and source product( s). 64 4 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

5 Data are not required because the PAI is a solid at room temperature.

6 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

7 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

8 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

9 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 65 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: NuFarm USA, Inc. Product( s): 66.18% DMA FI ( EPA Reg. No. 61272 8)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF 1/ 28/ 93 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y CSF 1/ 28/ 93 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 3 830.7220 Boiling point/ boiling range N/ A 4 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 5 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 6 830.7840 Water solubility: column elution method; shake flask method Y 43358801 7 830.7950 Vapor pressure Y 42021001 8 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 The CSF was obtained from the product jacket and was reviewed under Registration Division Memorandum D209172, 1/ 17/ 95, S. Mathur; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 66 4 Data are not required because the PAI is a solid at room temperature.

5 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

6 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

7 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

8 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 67 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 67.1% DMA FI ( EPA Reg. No. 62719 27)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 41055809, 41055810, 41964401 4 830.1600 Description of materials used to produce the product Y 41055809 830.1650 Description of formulation process Y 41055809 830.1670 Discussion of formation of impurities Y 41055809, 41964401 4, 42798101 5 830.1700 Preliminary analysis Y 41055810, 41964401 4, 43314701 6 830.1750 Certified limits N 7 41055809, 41055810, 41964401 4 830.1800 Enforcement analytical method Y 41055810 830.6302 Color Y 41055811 830.6303 Physical state Y 41055811 830.6304 Odor Y 41055811 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41755701 8 830.6314 Oxidation/ reduction: chemical incompatibility Y 41055811 830.6315 Flammability Y 41055811 830.6316 Explodability Y 41055811 830.6317 Storage stability Y 41055811 830.6319 Miscibility N/ A 9 830.6320 Corrosion characteristics Y 41055811 830.7000 pH Y 41055811 830.7050 UV/ Visible absorption N 10 830.7100 Viscosity Y 41055811 830.7200 Melting point/ melting range Y 42829901 11 830.7220 Boiling point/ boiling range N/ A 12 830.7300 Density/ relative density/ bulk density Y 41055811 830.7370 Dissociation constants in water N/ A 13 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 14 830.7840 Water solubility: column elution method; shake flask method Y 41055811, 42021002 4, 43358801 15 830.7950 Vapor pressure Y 42021001 4 1 Y = Yes; N = No; N/ A = Not Applicable.

2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted. 68 3 Nominal concentrations are required which reflect the expected amount of the impurities in the final product.

4 D170802, 7/ 24/ 92.

5 D192564, 9/ 7/ 93, K. Dockter.

6 D205982, 2/ 14/ 95, K. Dockter.

7 Certified limits are required for the active ingredient, and the registrant must confirm the certified limits proposed for the impurities and confirm the site of production.

8 D161051, 4/ 25/ 91, R. Perfetti.

9 Data are not required because the FI is not an emulsifiable liquid to be diluted with petroleum solvents.

10 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

11 D193116, 1/ 24/ 94, F. Toghrol.

12 Data are not required because the practical equivalent of the TGAI is a solid at room temperature.

13 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson 14 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti.

15 D207979, 2/ 22/ 96, D. Miller. 69 Case No. 0073 Chemical No. 030019 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 66.8% DMA FI ( EPA Reg. No. 62719 52)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSFs 4/ 24/ 01 830.1600 Description of materials used to produce the product N 830.1650 Description of formulation process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits Y CSFs 4/ 24/ 01 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability Y 45642701 3 830.6319 Miscibility N 830.6320 Corrosion characteristics Y 45642701 3 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range Y 42829901 4 830.7220 Boiling point/ boiling range N/ A 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N/ A 6 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 7 830.7840 Water solubility: column elution method; shake flask method Y 43358801 8 830.7950 Vapor pressure Y 42021001 9 1 Y = Yes; N = No; N/ A = Not Applicable. This product is produced in an integrated system from an EPAregistered 2,4 D acid product.

2 The CSFs for the basic and three alternate formulations were obtained from the product jacket and were reviewed by the Registration Division, letter dated 6/ 1/ 01, J. Miller; all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members 3 RD Memorandum, D282901, 8/ 6/ 02, L. Kutney. 70 4 D193116, 1/ 24/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

5 Data are not required because the PAI is a solid at room temperature.

6 Data are not required because the DMA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

7 Data are not required for the DMA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D161051, 4/ 25/ 91, R. Perfetti ( data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

8 D207979, 2/ 22/ 96, D. Miller ( TGAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27).

9 D170802, 7/ 24/ 92, ( PAI data for the Dow AgroSciences 67.1% DMA FI, EPA Reg. No. 62719 27). 71 Case No. 0073 Chemical No. 030025 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 49.9% IPA T ( EPA Reg. No. 62719 71)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41055815, 41055816, 41978001 3, 44807001 4, CSFs 5/ 17/ 01 5 830.1600 Description of materials used to produce the product Y 41055815 830.1620 Description of production process Y 41055815, 44727101 6, 44807001 4 830.1670 Discussion of formation of impurities Y 41055815, 41978001 3, 42798301 7, 44727101 6, 44807001 4 830.1700 Preliminary analysis Y 41055816 830.1750 Certified limits Y 41055815, 41055816, 41978001 3, 44807001 4, CSFs 5/ 17/ 01 5 830.1800 Enforcement analytical method Y 41055816 830.6302 Color Y 41055817 830.6303 Physical state Y 41055817 830.6304 Odor Y 41055817 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41978002 3 830.6314 Oxidation/ reduction: chemical incompatibility Y 41055817 830.6315 Flammability Y 41055817 830.6316 Explodability Y 41055817 830.6317 Storage stability Y 41055817, 43874601 8 830.6319 Miscibility N/ A 9 830.6320 Corrosion characteristics Y 41055817 830.7000 pH Y 41055817 830.7050 UV/ Visible absorption N 10 830.7100 Viscosity Y 41055817 830.7200 Melting point/ melting range Y 42831001 11 830.7220 Boiling point/ boiling range N/ A 12 830.7300 Density/ relative density/ bulk density Y 41055817 830.7370 Dissociation constants in water N/ A 13 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 14 830.7840 Water solubility: column elution method; shake flask method Y 41978001 3, 43358802 15 830.7950 Vapor pressure Y 41431101 6 72 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted.

3 D167944, 6/ 30/ 92, S. Funk.

4 RD Memorandum, D255728, 5/ 5/ 99, S. Mathur.

5 CSFs dated 5/ 17/ 01 for the basic and three alternate formulations were obtained from the product jacket and reviewed under RD Memorandum, D275675, 8/ 8/ 01, S. Malak.

6 RD Memorandum D253591, 3/ 11/ 99, S. Mathur.

7 D192565 and D194929, 11/ 9/ 93, F. Toghrol.

8 D221847, 3/ 28/ 97, K. Dockter.

9 Data are not required because the FI is not an emulsifiable liquid to be diluted with petroleum solvents.

10 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

11 D193112, 9/ 7/ 93, K. Dockter.

12 Data are not required because the practical equivalent of the TGAI is a solid at room temperature.

13 Data are not required because the IPA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson.

14 Data are not required for the IPA salt TGAI because it is a polar organic compound; no additional data were required for this data requirement under D167944, 6/ 30/ 92, S. Funk.

15 D207979, 2/ 22/ 96, D. Miller. 73 Case No. 0073 Chemical No. 030035 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 71% TIPA FI ( EPA Reg. No. 62719 180)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41055818, 41055819, CSF 7/ 9/ 98 3 830.1600 Description of materials used to produce the product Y 41055818 830.1620 Description of production process Y 41055818, 44228301 4 830.1670 Discussion of formation of impurities Y 41055818, 42798201 5, 44228301 4 830.1700 Preliminary analysis Y 41055819, 44620501 3 830.1750 Certified limits Y 41055818, 41055819, CSF 7/ 9/ 98 3 830.1800 Enforcement analytical method Y 41055819 830.6302 Color Y 41055820 830.6303 Physical state Y 41055820 830.6304 Odor Y 41055820 830.6313 Stability to normal and elevated temperatures, metals, and metal ions N 830.6314 Oxidation/ reduction: chemical incompatibility Y 41055820 830.6315 Flammability Y 41055820 830.6316 Explodability Y 41055820 830.6317 Storage stability Y 41055820 830.6319 Miscibility N/ A 6 830.6320 Corrosion characteristics Y 41055820 830.7000 pH Y 41055820 830.7050 UV/ Visible absorption N 7 830.7100 Viscosity Y 41055820 830.7200 Melting point/ melting range Y 43325003 8 830.7220 Boiling point/ boiling range N/ A 9 830.7300 Density/ relative density/ bulk density Y 41055820 830.7370 Dissociation constants in water N/ A 10 830.7550 Partition coefficient ( n octanol/ water), shake flask method N/ A 11 830.7840 Water solubility: column elution method; shake flask method N 830.7950 Vapor pressure N 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from an EPA registered acid product; the registrant must submit product chemistry data for the practical equivalent of the DMA salt TGAI and for the manufacturing use product.

2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted. 74 3 Registration Division Memorandum, D250352, 10/ 27/ 98, S. Mathur.

4 Registration Division Memorandum, D240644, 2/ 9/ 98, S. Mathur.

5 D192562, 9/ 7/ 93, K. Dockter.

6 Data are not required because the FI is not an emulsifiable liquid to be diluted with petroleum solvents.

7 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

8 D207072, 9/ 29/ 94, F. Toghrol.

9 Data are not required because the practical equivalent of the TGAI is a solid at room temperature.

10 Data are not required because the TIPA salt completely dissociates in aqueous solutions; data for 2,4 D acid were accepted to fulfill this requirement under CBRS Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson.

11 The Agency has determined that data are not required for the TIPA salt TGAI because it is a polar organic compound 75 Case No. 0073 Chemical No. 030053 Case Name: 2,4 D Registrant: NuFarm Americas, Inc. Product( s): 94% BEE T ( EPA Reg. No. 228 136)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N CSF 11/ 5/ 79 830.1600 Description of materials used to produce the product N 830.1620 Description of production process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits N CSF 11/ 5/ 79 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 42487901 3 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 4 830.7220 Boiling point/ boiling range Y 43325001 5 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water N 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y Letter 6 830.7840 Water solubility: column elution method; shake flask method Y 41669501 7, 42830901 8 830.7950 Vapor pressure Y 41431301 9 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF was obtained from the product jacket; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members.

3 D183498, 3/ 3/ 93, K. Dockter ( TGAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33).

4 Data are not required because the TGAI is a liquid at room temperature. 76 5 D207072, 9/ 29/ 94, F. Toghrol ( TGAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33).

6 D161373, 4/ 16/ 91, W. Smith ( PAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33).

7 CB 7545, 2/ 19/ 91, H. Fonouni ( PAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33).

8 D193113, 1/ 26/ 94, F. Toghrol ( PAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33).

9 D175586, 7/ 23/ 92, S. Funk ( PAI data for the Dow AgroSciences 94.5% BEE T, EPA Reg. No. 62719 33). 77 Case No. 0073 Chemical No. 030053 Case Name: 2,4 D Registrant: Dow AgroSciences LLC Product( s): 94.5% BEE T ( EPA Reg. No. 62719 33)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y 41055812, 41055813, 41961301 3, CSF 5/ 26/ 98 4 830.1600 Description of materials used to produce the product Y 41055812, 44584501 4 830.1620 Description of production process Y 41055812, 44584501 4 830.1670 Discussion of formation of impurities Y 41055812, 41961301 3, 44584501 4 830.1700 Preliminary analysis N 5 41055813 830.1750 Certified limits Y 41055812, 41055813, 41961301 3, CSF 5/ 26/ 98 4 830.1800 Enforcement analytical method Y 41055813 830.6302 Color Y 41055814 830.6303 Physical state Y 41055814 830.6304 Odor Y 41055814 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 42487901 6 830.6314 Oxidation/ reduction: chemical incompatibility Y 41055814 830.6315 Flammability Y 41055814 830.6316 Explodability Y 41055814 830.6317 Storage stability Y 41055814 830.6319 Miscibility N/ A 7 830.6320 Corrosion characteristics Y 41055814 830.7000 pH N 830.7050 UV/ Visible absorption N 9 830.7100 Viscosity Y 41055814 830.7200 Melting point/ melting range N/ A 10 830.7220 Boiling point/ boiling range Y 42830901 11, 43325001 12 830.7300 Density/ relative density/ bulk density Y 41055814 830.7370 Dissociation constants in water N 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41647001 13, Letter 14 830.7840 Water solubility: column elution method; shake flask method Y 41669501 15, 42830901 11 830.7950 Vapor pressure Y 41431301 16 1 Y = Yes; N = No; N/ A = Not Applicable.

2 Bolded references were reviewed under CB Nos. 5454, 5455, 5489, 5540, 5541, 5542, 5543, and 5544, 10/ 25/ 89, M. Nelson; and all other references were reviewed as noted. 78 3 Initially reviewed under CB Nos. 8426, 8430, and 8433, 9/ 8/ 92, F. Toghrol; and re evaluated under D189600, 3/ 11/ 94, F. Toghrol.

4 Registration Division Memorandum, D247475, 7/ 24/ 98, A. Smith.

5 Adequate preliminary analysis data have been submitted; however, the registrant must either conduct analysis of seven batches of the technical product for dioxins and dibenzofurans or present information to show that dioxins/ dibenzofurans will not form during manufacture.

6 D183498, 3/ 3/ 93, K. Dockter.

7 Data are not required because the T is not an emulsifiable liquid to be diluted with petroleum solvents.

8 Data are not required because the BEE TGAI is an organic liquid which can not be diluted or dispersed in water.

9 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

10 Data are not required because the T/ TGAI is a liquid at room temperature.

11 D193113, 1/ 26/ 94, F. Toghrol.

12 D207072, 9/ 29/ 94, F. Toghrol.

13 CB No. 7206, 11/ 21/ 90, H. Fonouni.

14 D161373, 4/ 16/ 91, W. Smith.

15 CB No. 7545, 2/ 19/ 91, H. Fonouni.

16 D175586, 7/ 23/ 92, S. Funk. 79 Case No. 0073 Chemical No. 030063 Case Name: 2,4 D Registrant: PBI/ Gordon Corporation Product( s): 93.3% 2 EHE T ( EPA Reg. No. 2217 706)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition Y CSF 2/ 1/ 00 830.1600 Description of materials used to produce the product Y 44963803 3 830.1620 Description of production process Y 44963803 3 830.1670 Discussion of formation of impurities Y 44963803 3 830.1700 Preliminary analysis Y 44963801 3 830.1750 Certified limits Y 44963804 3, CSF 2/ 1/ 00 830.1800 Enforcement analytical method Y 44963804 3 830.6302 Color Y 44963802 3 830.6303 Physical state Y 44963802 3 830.6304 Odor Y 44963802 3 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41968303 4, 44963802 3 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH Y CSF 3 830.7050 UV/ Visible absorption N 5 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 6 830.7220 Boiling point/ boiling range Y 44963802 3 830.7300 Density/ relative density/ bulk density Y 44963802 3 830.7370 Dissociation constants in water Y 41332009 7 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 44963802 3 830.7840 Water solubility: column elution method; shake flask method Y 42831101 8, 44963802 3 830.7950 Vapor pressure Y 44963802 3 1 Y = Yes; N = No; N/ A = Not Applicable.

2 The CSF dated 2/ 1/ 00 was obtained from the product jacket and reviewed by the Registration Division, letter dated 2/ 14/ 00, from J. Miller ( RD) to C. Martens of PBI/ Gordon Corporation; all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members 3 RD Letter dated 1/ 18/ 00, from J. Miller ( RD) to C. Martens of PBI/ Corporation. 80 4 D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol ( TGAI data for the Dow AgroSciences 95.4% 2 EHE T, EPA Reg. No. 62719 26).

5 The OPPTS Series 830, Product Properties Test Guidelines require data pertaining to UV/ visible absorption for the PAI.

6 Data are not required because the TGAI is a liquid at room temperature.

7 CB 6581, 7/ 27/ 90, G. Makhijani ( Task Force submission).

8 D193115, 11/ 24/ 93, F. Toghrol ( TGAI data for the Dow AgroSciences 95.4% 2 EHE T, EPA Reg. No. 62719 26). 81 Case No. 0073 Chemical No. 030063 Case Name: 2,4 D Registrant: NuFarm Limited Product( s): 94% 2 EHE T ( EPA Reg. No. 35935 12)

PRODUCT CHEMISTRY DATA SUMMARY Guideline Number Requirement Are Data Requirements Fulfilled? 1 MRID Number 2 830.1550 Product identity and composition N 3 CSF 12/ 27/ 88 ( basic) CSF 12/ 20/ 88 ( alternate) 830.1600 Description of materials used to produce the product N 830.1620 Description of production process N 830.1670 Discussion of formation of impurities N 830.1700 Preliminary analysis N 830.1750 Certified limits N 3 CSF 12/ 27/ 88 ( basic) CSF 12/ 20/ 88 ( alternate) 830.1800 Enforcement analytical method N 830.6302 Color N 830.6303 Physical state N 830.6304 Odor N 830.6313 Stability to normal and elevated temperatures, metals, and metal ions Y 41968303 4 830.6314 Oxidation/ reduction: chemical incompatibility N 830.6315 Flammability N 830.6316 Explodability N 830.6317 Storage stability N 830.6319 Miscibility N 830.6320 Corrosion characteristics N 830.7000 pH N 830.7050 UV/ Visible absorption N 830.7100 Viscosity N 830.7200 Melting point/ melting range N/ A 5 830.7220 Boiling point/ boiling range Y 43325002 6, 44963802 7 830.7300 Density/ relative density/ bulk density N 830.7370 Dissociation constants in water Y 41332009 8 830.7550 Partition coefficient ( n octanol/ water), shake flask method Y 41055808 9, 44963802 7 830.7840 Water solubility: column elution method; shake flask method Y 41055808 9, 42831101 10, 44963802 7 830.7950 Vapor pressure Y 41055808 9, 44963802 7 1 Y = Yes; N = No; N/ A = Not Applicable. This product is manufactured from EPA registered acid products; the registrant must submit product chemistry for the practical equivalent of the 2 EHE TGAI and for the manufacturing use product.

2 The CSFs were obtained from the product jacket; and all other references were reviewed as noted. Italicized references reflect TGAI and/ or PAI data for phys/ chem requirements which may be shared by Task Force members. 82 3 We note that the source of the technical acid cited for the alternate formulation has been canceled; the CSFs for the basic and alternate formulations must be revised to reflect the current registrant, EPA Reg. Nos., and sources.

4 D167642, D167684, and D167644, 9/ 8/ 92, F. Toghrol ( TGAI data for the Dow AgroSciences 95.4% 2 EHE T, EPA Reg. No. 62719 26).

5 Data are not required because the TGAI is a liquid at room temperature.

6 D207072, 9/ 29/ 94, F. Toghrol ( TGAI data for the Dow AgroSciences 95.4% 2 EHE T, EPA Reg. No. 62719 26).