  SEQ CHAPTER \h \r 1

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES

MEMORANDUM

DATE:  	Jan 14, 2010

SUBJECT:	Acetamiprid.  Revised Acute and Chronic Dietary Exposure Assessments (Food and Drinking Water) to Support Section 3 Registration of Uses on Clover, Small Vine Climbing Fruits, except Fuzzy Kiwifruit, Subgroup 13-07F, Greenhouse Grown Tomatoes and Tea.

PC Code:  099050	DP Barcode:  D372890

Decision No.:  408298	Registration Nos.:  8033-23,  8033-36, 8033-94

Petition No.:  9E7544	Regulatory Action:  Amended Section 3

Risk Assessment Type:  Single Chemical Aggregate, Dietary	Case No.:  N/A

TXR No.:  N/A	CAS No.:  135410-20-7

MRID Nos.:  N/A	40 CFR:  §180.578

REVIEWER:	Dennis McNeilly, Chemist

Registration Action Branch 2

Health Effects Division (7509P)

THROUGH:	Julie Van Alstine, MPH, Environmental Health Scientist

Douglas Dotson, Ph.D., Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

TO:			Laura Nollen, Risk Manager Reviewer

			Barbara Madden, Team Leader (RM Team 5)

			RIMUERB/Registration Division (RD) (7505P)

Executive Summary

 (DEEM-FCID™, Version 2.03) which uses food consumption data from the USDA’s Continuing Surveys of Food Intakes by Individuals (CSFII, 1994-1996 and 1998).  Analyses were previously performed to support the requested Section 3 registration of acetamiprid on clover, small vine climbing fruits, except kiwifruit, subgroup 13-07F (amending grape use); green house grown tomatoes; and tea (D369019, D. McNeilly, 12/1/2009).  RD has requested that HED redo the analyses using 100% percent crop treated for all amended commodities, i.e., grapes and other subgroup 13-07F commodities, and tomatoes.

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

The probabilistic acute dietary exposure assessment included tolerance level residues, anticipated residues from field residue trials, processing factors, maximum percent crop treated (%CT) estimates (for existing uses only) generated by the Biological and Economic Analysis Division (BEAD), and the modeled peak concentration of acetamiprid residues in surface and groundwater water sources of drinking water.  Although the acute assessment has been refined, the resulting exposure estimates are still considered to be conservative since field trial data were the basis for the anticipated residues, and because a conservative drinking water model (FIRST) was used to estimate residues in drinking water.

Acute dietary exposure estimates at the 99.9th percentile are below HED’s level of concern for the general US population and all other population subgroups.  For the US population, the estimated exposure of 0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, the estimated exposure of 0.043 mg/kg/day corresponds to an acute dietary risk of 43% aPAD.

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization

For the chronic analysis, tolerance-level residues were assumed for all food commodities with existing and proposed acetamiprid tolerances.  Percent crop treated was used for many commodities as detailed in Table 3.  The chronic analysis also included the modeled surface water annual average residue in drinking water.  Even though %CT information was used in the chronic analysis, the exposure and risk estimates are still conservative since tolerance level residues were used, because 100 %CT was assumed for crops where percent crop treated information was not available, and because a conservative drinking water model (FIRST) was used.

Chronic dietary exposure to acetamiprid, including existing and proposed uses, is below HED’s level of concern for the US population and all other population subgroups.  For the general US population, an estimated exposure of 0.0028 mg/kg/day corresponds to 4% of the chronic population adjusted dose (cPAD); children 1-2 years old was the highest exposed population subgroup, with an estimate of 0.010 mg/kg/day, or 15% cPAD.  Risks for all population subgroups are less than 100% cPAD, and are not of concern.

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects).  This dose is referred to as the population adjusted dose (PAD).  The PAD is equivalent to a point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site:  “Available Information on Assessing Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link:    HYPERLINK http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see SOP 99.6 (8/20/99).

The most recent dietary risk assessment for acetamiprid was conducted by D. McNeilly (D369019, 12/1/09) which included proposed uses on clover, small vine climbing fruits, except kiwifruit, subgroup 13-07F (amending grape use); green house grown tomatoes; and tea.  RD has requested that HED redo the analyses using 100% percent crop treated for all amended commodities, i.e., grapes and other subgroup 13-07F commodities, and tomatoes.

II.	Residue Information

Tolerances are established for residues of the insecticide acetamiprid [40 CFR §180.578(a)], N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1- methylacetamidine, in or on numerous agricultural commodities ranging from 0.01 ppm on mustard and canola seed to 20 ppm in or on cotton, gin byproducts.  Tolerances are established for the combined residues of the insecticide acetamiprid, N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1- methylacetamidine, and its metabolite N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano- acetamidine [40 CFR §180.578(b)] in or on fat and meat of cattle, goat, hog, horse and sheep, 0.1 ppm; meat by-products of cattle, goat, hog horse and sheep, 0.2 ppm; milk, 0.1 ppm; poultry meat and fat, 0.01 ppm; poultry liver, 0.05 ppm; and egg, 0.01 ppm.

The current acute and chronic dietary exposure assessments include existing uses and the tolerances proposed by the Interregional Research Project Number 4 (IR-4).  IR-4 has submitted amended Section 3 registration requests for new uses of acetamiprid on clover grown for seed, small vine climbing fruits, except kiwifruit, subgroup 13-07F (amending established grape uses), greenhouse-grown tomatoes, and tea.

Table 1.  Recommended Tolerances

Crop Group or Commodity	Recommended Tol. (ppm)

Clover, forage*	0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].

Clover, hay*	0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].

Fruit, small, vine climbing, subgroup 13-07F, except fuzzy kiwifruit    0.35

Tea	50.0

Tomatoes (greenhouse grown)	Note:  No change is needed to the current tolerance in fruiting vegetables (Crop Group 8) at 0.2 ppm.

Acute Dietary Exposure Assessment

The acute dietary assessment was conducted using anticipated residues from field trials [apples; broccoli; cabbage, celery; grapefruit; grapes; lettuce; oranges; pears; peppers; spinach; tomatoes; stone fruit (crop group 12); and cucurbits (crop group 9)].  For each of the above-listed commodities, the individual field trial residue values (from trials reflecting the 1X application rate and labeled PHI, or shorter) were incorporated into a residue distribution file (RDF) for the probabilistic acute dietary exposure assessment.  For field trial residues below the limit of quantification (LOQ) of 0.01 ppm, a residue value of ½ LOQ, or 0.005 ppm was assumed.  For cabbage and head lettuce, residues in the RDF were for the raw agricultural commodity (RAC) without wrapper leaves.  For commodities with %CT data available, the RDF includes an indication of the number of zeroes assumed for the percent of the commodity not treated.  Tolerance level or HED-recommended tolerance level residues were used for tree nuts, nectarines, collards, cauliflower, legumes, berries, bulb vegetables and for livestock commodities.  For tea, the HED-recommended tolerance of 50 ppm was used.

A summary of the RDFs is included in Attachment 1.  The orange RDF was translated to grapefruit, using the higher percent crop treated estimate of 5% for oranges (grapefruit was <2.5%).  The plum RDF was translated to apricots and assumes 100% CT.  These translations are appropriate since the field trials were conducted on the representative crops, and cover potential residues in the related crops, and since either no adjustment for %CT was made (plums and apricots) or a conservative estimate of %CT was made in these RDFs.  100% crop treated was assumed for grapes and tomatoes because the use patterns are being amended for these commodities and projected crop treated estimates are not available.

Chronic Dietary Exposure Assessment

For the chronic dietary exposure assessment, current and recommended tolerance-level residues were used, for all RACs and livestock commodities.  Percent crop treated estimates were used for apple (20%), broccoli (5%), cabbage (5%), cauliflower (10%), celery (25%), cotton (5%), grapefruit (2.5%), lemon (5%), lettuce (10%), orange (2.5%), peach (1%), pear (35%), pepper (2.5%), potato (2.5%), pumpkin (1%), spinach (5%), and squash (2.5%).  100% crop treated was assumed for grapes and tomatoes because the use patterns are being amended for these commodities and projected crop treated estimates are not available.

Processing Factors

The acute dietary exposure assessment was refined with processing factors for apple juice, orange juice, grapefruit juice, raisins, dried prunes, tomato paste and tomato puree.  The processing factors were reviewed in conjunction with residue data used to determine if separate tolerances were needed for processed commodities.  For all other commodities, the DEEM™ Version 7.81 default processing factors were used.  Processing factors from study data were incorporated into the acute dietary assessment as follows (Table 2):

Table 2.  Summary of Processing Studies Conducted with Acetamiprid.

RAC	Processed Commodity	Processing Factor	Comments

Apple	Juice	0.88	Also used for pear juice

Citrus	Juice	<0.16	0.16X used for both orange and grapefruit juice

Grape	Juice	1	Study data showed RAC tolerance would cover residues in juice.

	Raisins	0.9	0.9X used in assessment

Tomato	Puree	1.4	1.4X used for puree in assessment

	Paste	3.0	3.0X used for paste in acute assessment.

Plum	Prune, dried	2.9X	2.0X used for dried prunes used in acute assessment.  The drying factor was translated to dried apricots and dried peaches in the acute dietary assessment.

For the chronic dietary exposure assessment, the DEEM™ Version 7.81 default processing factors were used for all commodities for which they are available, with the exception of grape juice, and raisins (dried prunes and tomato paste have separate tolerances).

Usage Data

In order to refine the dietary exposure estimates for acetamiprid, HED requested a Screening Level Usage Analysis (SLUA), which was conducted by the Biological and Economic Analysis Division (BEAD), 6/11/09.  The SLUA includes estimates of maximum %CT for the acute assessment and average %CT for determining chronic exposure.  Commodities with the most significant acetamiprid usage in terms of maximum %CT include pears (60%), apples (30%), celery (45%), and lettuce (20%).  Commodities with the most significant usage in terms of lbs ai applied include apples (10,000), cotton (20,000), and pears (5,000).  The SLUA is included as Attachment 3.

Table 3.   Percent Crop Treated Data Used in DEEM

Commodity	Avg	Max

Apples	20	30

Broccoli	5	15

Cabbage	5	10

Cauliflower	10	15

Celery	25	45

Cotton	5	5

Grapefruit	2.5	51

Lemons	5	100

Lettuce	10	20

Oranges	2.5	5

Peaches	1	2.5

Pears	35	60

Peppers	2.5	5

Potatoes	2.5	2.5

Pumpkins	1	2.5

Spinach	5	15

Squash	2.5	2.5

1  -  The residue distribution file for oranges which used 5% CT was also used for grapefruit.  This was higher than the 2.5% CT for grapefruit estimated by BEAD and is more conservative.

For the acute analysis, maximum %CT was incorporated into RDFs for the commodities in the above table.  For the chronic analysis, average %CT was included (as adjustment factor 2) for the commodities listed in the table above.

Incorporation of Potential Residues in Drinking Water

In a memo dated 6/10/09 [D. Lieu, D364248], EFED notified RD that new drinking water estimates would not be provided for the proposed use on red clover (grown for seed only), grape, and tomato (greenhouse) because the drinking water estimates derived from the uses on citrus and tree nuts reflect the maximum use patterns for acetamiprid.

In conjunction with the uses on citrus and tree nuts, the Environmental Fate and Effects Division (EFED) prepared an estimate of potential residues in drinking water [G. Orrick, Tier I Drinking Water Exposure Assessment for Acetamiprid on Cucurbit, Stone Fruit and Tree Nut Crop Groups, 6/21/05, D303582].  EFED stated in a June 10, 2009 memorandum (D364248, D. Lieu) that this assessment was still valid and should be used to assess the proposed uses on red clover (grown for seed), grape, and tomato (greenhouses).  Estimated drinking water concentrations for acetamiprid in surface water were generated using the FIRST (FQPA Index Reservoir Screening Tool, v. 1.0) Model.  The results of the model reflect potential residues in a small drinking water reservoir surrounded by a runoff-prone watershed, assuming maximum pesticide application rates and no buffer between the reservoir and treated fields.  Acetamiprid residues in ground water sources of drinking water were estimated using the screening regression model SCI-GROW (Screening Concentration In Ground Water, v. 2.3).  The SCI-GROW residue estimate is based on environmental fate properties of the pesticide, maximum application rates, and existing data from small-scale prospective ground-water monitoring studies in vulnerable sites.

For surface water, the maximum application rate for the existing use of acetamiprid on citrus was used to provide model estimates of drinking water concentrations; for ground water, the proposed use on tree nut crops was used.  However, since modeled surface water residues were considerably higher than ground water residues, only the surface water residues were used quantitatively in the dietary (food + water) assessment.

Table 4.  Tier I Analysis

1-in-10-year EDWCs in surface water and ground water for acetamiprid.

Drinking Water Source	Maximum Use Pattern	Exposure	EDWC

Surface water	Citrus fruit	Peak	20.1     ppb

Annual average	  4.9     ppb

Ground water	Tree nut	Peak & annual average	  1.6     ppt

For the acute assessment, an estimated drinking water concentration of 20.1 ppb was entered into the DEEM™-FCID Model for “water, direct, all sources” and “water, indirect, all sources.”  For the chronic assessment, the value of 4.9 ppb was used.  The ground water estimate of 1.6 ppt was much lower than surface water residues; therefore, dietary exposure and risk calculated using surface water residues are considered protective of potential exposure through ground water.

III.	Exposure Model and Consumption Information

Acetamiprid acute and chronic dietary exposure assessments were conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database DEEM-FCID™,Version 2.03 which incorporates consumption data from USDA’s Continuing Surveys of Food Intakes by Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98 data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups, but for acute exposure assessment are retained as individual consumption events.  Based on analysis of the 1994-96, 98 CSFII consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue intake estimate.  The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD.  This procedure is performed for each population subgroup.

For acute exposure assessments, individual one-day food consumption data are used on an individual-by-individual basis.  The reported consumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple random pairings with residue values and then summed in a probabilistic assessment.  The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis.  In accordance with HED policy, per capita exposure and risk are reported for all tiers of analysis.  However, for tiers 1 and 2, any significant differences in user vs. per capita exposure and risk are specifically identified and noted in the risk assessment.

IV.	Toxicological Information

Doses and endpoints selected for acute and chronic dietary exposure and risk assessments are summarized as shown in Table 5, below.  Details regarding hazard characterization and endpoint selection can be found in the risk assessment associated with the proposed uses [D369474, Dennis McNeilly, Dec 1, 2009].

Table 5.  Acetamiprid Toxicological Doses/Endpoints for Dietary Risk Assessment.

Exposure Scenario	Point of Departure	Uncertainty/FQPA Safety Factors RfD, PAD, Level of Concern 	Study and Toxicological Effects

Acute Dietary

[All Populations]

	NOAEL=10.0

mg/kg/day

	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Acute RfD = 0.10 mg/kg/day

aPAD = 0.10 mg/kg/day	Developmental Neurotox., Rat

LOAEL = 45.0 mg/kg/day based on decreased startle response on PND20/60 in males

Co Critical study -

Acute Neurotox., Rat

LOAEL = 30 mg/kg/day based on reduced locomotor activity in males.

Chronic Dietary

[all populations]	NOAEL = 7.1 mg/kg/day

	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Chronic RfD =

0.071 mg/kg/day

cPAD = 0.071 mg/kg/day	Chronic/oncogenicity, Rat

LOAEL= 17.5 mg/kg/day based on reduced body weight and body weight gain (♀) and hepatocellular vacuolation (♂).

Cancer (All routes)	Not likely to be a human carcinogen.

V.	Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD.  For both the acute and chronic analyses, the estimated dietary exposures are below HED’s level of concern for all population subgroups; the most highly exposed population subgroup for both acute and chronic durations is children 1-2 years old.

Acute dietary exposure estimates at the 99.9th percentile are below HED’s level of concern for the general US population and all other population subgroups.  For the US population, the estimated exposure of 0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, the estimated exposure of 0.043 mg/kg/day corresponds to an acute dietary risk of 43% aPAD.

Chronic dietary exposure to acetamiprid is below HED’s level of concern for the US population and all other population subgroups.  For the general US population, an estimated exposure of 0.0028 mg/kg/day corresponds to 4% of the chronic population adjusted dose (cPAD); children 1-2 years old were the highest exposed population subgroup, with an estimate of 0.010 mg/kg/day, or 15 % cPAD.  Risks for all population subgroups are less than 100 % cPAD, and are not of concern.

The results of the acute and chronic analyses are shown in Tables 6 and 7.

Table 6.  Results of Acetamiprid Acute Dietary (Food + Water) Exposure Analysis.

Population Subgroup	aPAD (mg/kg/day)	95th Percentile	99th Percentile 99.9th Percentile

Exposure (mg/kg/day)	% aPAD	Exposure (mg/kg/day)	% aPAD	Exposure (mg/kg/day)	% aPAD

General U.S. Population	0.10	0.006752	6.8	0.012367	12	0.023768	24

All Infants (< 1 year old)	0.10	0.012043	12	0.020075	20	0.031227	31

Children 1-2 years old	0.10	0.016770	17	0.025337	25	0.042928	43

Children 3-5 years old	0.10	0.012277	12	0.020279	20	0.034282	34

Children 6-12 years old	0.10	0.007509	7.5	0.013299	13	0.024123	24

Youth 13-19 years old	0.10	0.004686	4.7	0.007810	7.8	0.017682	18

Adults 20-49 years old	0.10	0.004600	4.6	0.007685	7.7	0.015543	16

Adults 50+ years old	0.10	0.004671	4.7	0.007822	7.8	0.013291	13

Females 13-49 years old	0.10	0.004632	4.6	0.007277	7.3	0.013133	13

Table 7.  Summary of Dietary (Food + Water) Exposure and Risk for Acetamiprid

Population Subgroup	Acute Dietary

(99.9th Percentile)	Chronic Dietary

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure (mg/kg/day)	% cPAD

General U.S. Population	0.023768	24	0.002835	4.0

All Infants (< 1 year old)	0.031227	31	0.005206	7.3

Children 1-2 years old	0.042928	43	0.010358	15

Children 3-5 years old	0.034282	34	0.007296	10

Children 6-12 years old	0.024123	24	0.004055	5.7

Youth 13-19 years old	0.017682	18	0.002170	3.1

Adults 20-49 years old	0.015543	16	0.002031	2.9

Adults 50+ years old	0.013291	13	0.002130	3.0

Females 13-49 years old	0.013133	13	0.002057	2.9

VI.	Characterization of Inputs/Outputs

The acute dietary exposure assessment for acetamiprid is somewhat refined, since field trial residue distributions were used in the probabilistic assessment, and percent crop treated information was incorporated for some commodities.  In addition, empirical processing factors for various processed commodities, especially juices, provided an additional measure of refinement.  However, the assessment is still somewhat conservative because tolerance-level residues were used for proposed uses and some of the existing uses, as well as livestock commodities.  Additional refinements could be made to the assessment with the use of additional field trial residue data.  Even though the acute probabilistic assessment has not been completely refined, acute dietary exposure and risk estimates for acetamiprid are below HED’s level of concern of 100 % aPAD.

The chronic dietary exposure assessment is unrefined, with the exception of the use of %CT data cited in Table 3.  For all commodities, tolerance level residues were used, and DEEM 7.81 default processing factors were applied.  Further refinements are possible in the future, including the use of average field trial residues, empirical processing factors and additional %CT refinements.

VII.	Conclusions

Acute and chronic dietary (food + water) risks for acetamiprid are below HED’s level of concern for dietary exposure and risk.  Children 1-2 years old are the most highly exposed population subgroup, with risks of 43% aPAD for acute and 15% cPAD for chronic.  Risks were lower for all other population subgroups, including the general US population.  The acute and chronic dietary exposure assessments support the new uses proposed for acetamiprid.

VIII.	List of Attachments

Attachment 1.	Acetamiprid Residue Distribution Files

Attachment 2.	Acetamiprid Screening Level Usage Analysis (SLUA)

Attachment 4.	Acute Residue Input Files

Attachment 5	Summary of Acute Results

Attachment 6.	Chronic Residue Input File

Attachment 7.	Summary of Chronic Results

Attachment 1.	Acetamiprid Residue Distribution Files

Acetamiprid/Apple

TOTALZ=149

Est. Max. %CT = 30

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24	Acetamiprid/Broccoli

Estimated max %CT = 15

TOTALZ=130

MRID No. 44988631

0.02, 0.04, 0.04, 0.05, 0.01

0.01, 0.005, 0.02, 0.01, 0.02

0.005, 0.01, 0.07, 0.11, 0.18

0.25, 0.02, 0.097, 0.10, 0.080

0.092, 0.081, 0.10	Acetamiprid/Cabbage

w/out wrapper leaves, 10 %CT

TOTALZ=180

MRID No. 44988631

0.005, 0.02, 0.005, 0.01, 0.005

0.005, 0.005, 0.005, 0.03, 0.03

0.005, 0.005, 0.01, 0.02, 0.02

0.02, 0.05, 0.05, 0.03, 0.03	Acetamiprid/Celery

Estimated Max. %CT = 45

TOTALZ=20

MRID No. 44988603

0.775, 0.780, 0.167, 0.182

0.396, 0.426, 0.287, 0.352

0.250, 0.290, 0.255, 0.281

0.499, 0.517, 0.068, 0.084

Acetamiprid/Cucurbit

Assume 100%CT

MRID No. 46265701

0.024, 0.038, 0.015, 0.026

0.024, 0.030, 0.038, 0.045

0.082, 0.091, 0.017, 0.019

0.070, 0.090, 0.035, 0.076

0.011, 0.026, 0.011, 0.021

0.035, 0.037, 0.065, 0.142, 0.091, 0.094, 0.075, 0.136

0.053, 0.068, 0.166, 0.221

0.004, 0.075	Acetamiprid/Grape

Assume 100% CT

TOTALZ=0

MRID No. 47716902

0.05, 0.05, 0.03, 0.03, 0.01, 0.01, 0.08, 0.08, 0.17, 0.15, 0.08, 0.09, 0.08, 0.08, 0.2,

0.21, 0.24, 0.25, 0.1, 0.11,

0.06, 0.06, 0.22, 0.22, 0.04, 0.04, 0.07, 0.06, 0.04, 0.03, 0.15, 0.15, 0.24, 0.22, 0.13,

0.13	Acetamiprid/Head Lettuce

MRID No. 44988603

Estimated Max. %CT = 20%

TOTALZ=72

0.155, 0.184, 0.253, 0.294, 0.017, 0.018, 0.047, 0.057

0.005, 0.005, 0.060, 0.061

0.014, 0.014, 0.010, 0.010

0.074, 0.14

	Acetamiprid/Leaf Lettuce

Estimated Maximum %CT=20

TOTALZ=80

MRID No. 44988603

0.716, 1.02, 0.108, 0.123

0.565, 0.646, 0.265, 0.330

0.374, 0.449, 0.848, 1.07

0.098, 0.114, 0.435, 0.479

0.12, 0.18, 0.074, 0.14

Acetamiprid/Orange

TOTALZ=1235

Est. max %CT=5

MRID No. 4498611

0.14, 0.15, 0.11, 0.12, 0.09

0.13, 0.19, 0.29, 0.18, 0.21

0.29, 0.097, 0.11, 0.15, 0.21

0.20, 0.20, 0.058, 0.084, 0.088

0.15, 0.11, 0.15, 0.094, 0.12

0.19, 0.20, 0.19, 0.21, 0.26

0.29, 0.21, 0.23, 0.025, 0.025

0.13, 0.14, 0.081, 0.12, 0.14

0.14, 0.083, 0.12, 0.025, 0.025, 0.025, 0.025, 0.025, 0.098

0.23, 0.27, 0.12, 0.14, 0.079

0.096, 0.087, 0.12, 0.12, 0.16

0.31, 0.37, 0.16, 0.31, 0.26

0.39	Acetamiprid/Peach

Assume 2.5%CT

TOTALZ=1014

MRID No. 46265702

0.294, 0.344, 0.311, 0.565

0.184, 0.225, 0.163, 0.188

0.182, 0.223, 0.117, 0.138

0.153, 0.166, 0.283, 0.387

0.205, 0.233, 0.192, 0.240

0.211, 0.242, 0.0927, 0.133

0.186, 0.199	Acetamiprid/Pear

TOTALZ=42

Est. Max. %CT = 60

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24	Acetamiprid/Peppers

Estimated Max. %CT = 5

TOTALZ=570

MRID No. 44988616

0.005, 0.005, 0.01, 0.02, 0.01

0.01, 0.03, 0.05, 0.03, 0.04

0.01, 0.01, 0.02, 0.03, 0.02

0.02, 0.08, 0.09, 0.03, 0.03

0.06, 0.07, 0.04, 0.07, 0.05

0.06, 0.12, 0.16, 0.08, 0.08

Acetamiprid/Plum

Assume 100%CT

TOTALZ=0

MRID No. 46265702

0.108, 0.116, 0.0648, 0.119

0.0139, 0.0238, 0.0103, 0.0154

0.0515, 0.0624, 0.0401, 0.0429

0.0305, 0.0458, 0.0258, 0.0392	Acetamiprid/Spinach

Assume 15%CT

TOTALZ=125

MRID No. 44988603

0.034, 0.037, 0.184, 0.238

0.026, 0.036, 1.06, 1.20, 2.46

2.58, 0.516, 0.588, 1.95, 2.22

0.463, 0.466, 0.15, 0.23, 0.18

0.18, 0.19, 0.22	Acetamiprid/Tomatoes

Assume %CT=100

TOTALZ=0

MRIDs 44988616/47716903

0.01, 0.01, 0.005, 0.005, 0.005, 0.005, 0.01, 0.04, 0.08, 0.11

0.005, 0.01, 0.07, 0.08, 0.06

0.11, 0.02, 0.03, 0.02, 0.04

0.02, 0.02, 0.03, 0.03, 0.05

0.07, 0.03, 0.05, 0.06, 0.06

0.03, 0.05,  0.02, 0.02, 0.005

0.005, 0.047, 0.052, 0.005

0.005, 0.026, 0.028

Summary of Residue Distribution Files (RDF) listed in C:\Documents and Settings\Dmcneill\My Documents\Acetamiprid\PRIAacetamiprid_acuteAR.r98

 RDF      File        N residues   N residues  N Zeros

  #       Name         w freq's    w/o freq's

 ----  ------------   ----------   ----------  -------

  1    orange.RDF        0          65          1297

  2    Apple.RDF         0          64           149

  3    spinach.rdf       0          22           124

  4    cabbage.RDF       0          20           180

  5    peach.RDF         0          26          1114

  6    Plum.RDF          0          16             0

  7    Pear.RDF          0          64            43

  8    Broccoli.RDF      0          23           130

  9    Celery.RDF        0          16            20

  10   HeadLettuce.RDF   0          18            72

  11   LeafLettuce.RDF   0          20            80

  12   cucurbit.RDF      0          34             0

  13   Grapes.RDF        0          36             0

  14   Peppers.RDF       0          30           570

  15   Tomatoes.RDF      0          42             0

Attachment 2.	Acetamiprid Screening Level Usage Analysis (SLUA)

.	DEEM-FCID™ Acute Residue Input File

U.S. Environmental Protection Agency                                 Ver. 2.02

DEEM-FCID Acute analysis for ACETAMIPRID

Residue file name: C:\Documents and Settings\dmcneill\My Documents\Actemidprid\PRIAacetamiprid_acuteAR_2010.R98

Analysis Date 01-14-2010             Residue file dated: 01-14-2010/06:49:51/8

Reference dose: aRfD = 0.1 mg/kg bw/day  NOEL = 10 mg/kg bw/day

Comment: Acute/Chronic - UFs = 100

------------------------------------------------------------------------ --------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1           Param #2    Param #3    Comment

  #   Code

----- ---- ------------           ----------- ----------- ----------

  1    6   orange.RDF

  2    6   Apple.RDF

  3    6   spinach.rdf

  4    6   cabbage.RDF

  5    6   peach.RDF

  6    6   Plum.RDF

  7    6   Pear.RDF

  8    6   Broccoli.RDF

  9    6   Celery.RDF

  10   6   HeadLettuce.RDF

  11   6   LeafLettuce.RDF

  12   6   cucurbit.RDF

  13   6   Grapes.RDF

  14   6   Peppers.RDF

  15   6   Tomatoes.RDF

  EPA    Crop Food Name                         Def Res     Adj.Factors  RDL  Comment

  Code    Grp                                    (ppm)       #1     #2   Pntr

-------- ---- -------------------------------  ----------  ------ ------ ---  -------

14000030 14   Almond                             0.100000   1.000  1.000

14000031 14   Almond-babyfood                    0.100000   1.000  1.000

14000040 14   Almond, oil                        0.100000   1.000  1.000

14000041 14   Almond, oil-babyfood               0.100000   1.000  1.000

04010050 4A   Amaranth, leafy                    3.000000   1.000  1.000

11000070 11   Apple, fruit with peel             1.000000   1.000  1.000   2

11000080 11   Apple, peeled fruit                1.000000   1.000  1.000   2

11000081 11   Apple, peeled fruit-babyfood       1.000000   1.000  1.000   2

11000090 11   Apple, dried                       1.000000   8.000  1.000   2

11000091 11   Apple, dried-babyfood              1.000000   8.000  1.000   2

11000100 11   Apple, juice                       1.000000   0.880  1.000   2

11000101 11   Apple, juice-babyfood              1.000000   0.880  1.000   2

11000110 11   Apple, sauce                       1.000000   1.000  1.000   2

11000111 11   Apple, sauce-babyfood              1.000000   1.000  1.000   2

12000120 12   Apricot                            1.200000   1.000  1.000   6

12000121 12   Apricot-babyfood                   1.200000   1.000  1.000   6

12000130 12   Apricot, dried                     1.200000   2.900  1.000   6

12000140 12   Apricot, juice                     1.200000   1.000  1.000   6

12000141 12   Apricot, juice-babyfood            1.200000   1.000  1.000   6

01030150 1CD  Arrowroot, flour                   0.010000   1.000  1.000

01030151 1CD  Arrowroot, flour-babyfood          0.010000   1.000  1.000

01030170 1CD  Artichoke, Jerusalem               0.010000   1.000  1.000

04010180 4A   Arugula                            3.000000   1.000  1.000

09020210 9B   Balsam pear                        0.500000   1.000  1.000

06020310 6B   Bean, broad, succulent             0.400000   1.000  1.000

06020330 6B   Bean, cowpea, succulent            0.400000   1.000  1.000

06020370 6B   Bean, lima, succulent              0.400000   1.000  1.000

06010430 6A   Bean, snap, succulent              0.600000   1.000  1.000

06010431 6A   Bean, snap, succulent-babyfood     0.600000   1.000  1.000

21000440 M    Beef, meat                         0.100000   1.000  1.000

21000441 M    Beef, meat-babyfood                0.100000   1.000  1.000

21000450 M    Beef, meat, dried                  0.100000   1.920  1.000

21000460 M    Beef, meat byproducts              0.200000   1.000  1.000

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000  1.000

21000470 M    Beef, fat                          0.100000   1.000  1.000

21000471 M    Beef,fat-babyfood                  0.100000   1.000  1.000

21000480 M    Beef, kidney                       0.200000   1.000  1.000

21000490 M    Beef, liver                        0.200000   1.000  1.000

21000491 M    Beef, liver-babyfood               0.200000   1.000  1.000

13010550 13A  Blackberry                         1.600000   1.000  1.000

13010560 13A  Blackberry, juice                  1.600000   1.000  1.000

13010561 13A  Blackberry, juice-babyfood         1.600000   1.000  1.000

13020570 13B  Blueberry                          1.600000   1.000  1.000

13020571 13B  Blueberry-babyfood                 1.600000   1.000  1.000

13010580 13A  Boysenberry                        1.600000   1.000  1.000

14000590 14   Brazil nut                         0.100000   1.000  1.000

05010610 5A   Broccoli                           1.200000   1.000  1.000   8

05010611 5A   Broccoli-babyfood                  1.200000   1.000  1.000   8

05010620 5A   Broccoli, Chinese                  1.200000   1.000  1.000   8

05020630 5B   Broccoli raab                      1.200000   1.000  1.000

05010640 5A   Brussels sprouts                   1.200000   1.000  1.000

14000680 14   Butternut                          0.100000   1.000  1.000

05010690 5A   Cabbage                            1.200000   1.000  1.000   4

05020700 5B   Cabbage, Chinese, bok choy         1.200000   1.000  1.000

05010710 5A   Cabbage, Chinese, napa             1.200000   1.000  1.000

05010720 5A   Cabbage, Chinese, mustard          1.200000   1.000  1.000

09010750 9A   Cantaloupe                         0.500000   1.000  1.000

04020760 4B   Cardoon                            3.000000   1.000  1.000

09010800 9A   Casaba                             0.500000   1.000  1.000

14000810 14   Cashew                             0.100000   1.000  1.000

01030820 1CD  Cassava                            0.010000   1.000  1.000

01030821 1CD  Cassava-babyfood                   0.010000   1.000  1.000

05010830 5A   Cauliflower                        1.200000   1.000  1.000

04020850 4B   Celery                             3.000000   1.000  1.000   9

04020851 4B   Celery-babyfood                    3.000000   1.000  1.000   9

04020860 4B   Celery, juice                      3.000000   1.000  1.000   9

04020870 4B   Celtuce                            3.000000   1.000  1.000

09020880 9B   Chayote, fruit                     0.500000   1.000  1.000

12000900 12   Cherry                             1.200000   1.000  1.000

12000901 12   Cherry-babyfood                    1.200000   1.000  1.000

12000910 12   Cherry, juice                      1.200000   1.500  1.000

12000911 12   Cherry, juice-babyfood             1.200000   1.500  1.000

14000920 14   Chestnut                           0.100000   1.000  1.000

40000930 P    Chicken, meat                      0.010000   1.000  1.000

40000931 P    Chicken, meat-babyfood             0.010000   1.000  1.000

40000940 P    Chicken, liver                     0.050000   1.000  1.000

40000950 P    Chicken, meat byproducts           0.050000   1.000  1.000

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000  1.000

40000960 P    Chicken, fat                       0.010000   1.000  1.000

40000961 P    Chicken, fat-babyfood              0.010000   1.000  1.000

40000970 P    Chicken, skin                      0.010000   1.000  1.000

40000971 P    Chicken, skin-babyfood             0.010000   1.000  1.000

09021020 9B   Chinese waxgourd                   0.500000   1.000  1.000

19011030 19A  Chive                              4.500000   1.000  1.000

04011040 4A   Chrysanthemum, garland             3.000000   1.000  1.000

10001060 10   Citrus citron                      0.500000   1.000  1.000

10001070 10   Citrus hybrids                     0.500000   1.000  1.000

10001080 10   Citrus, oil                        0.500000   1.000  1.000

05021170 5B   Collards                           1.200000   1.000  1.000

95001280 O    Cottonseed, oil                    0.600000   1.000  1.000

95001281 O    Cottonseed, oil-babyfood           0.600000   1.000  1.000

11001290 11   Crabapple                          1.000000   1.000  1.000

95001300 O    Cranberry                          0.600000   1.000  1.000

95001301 O    Cranberry-babyfood                 0.600000   1.000  1.000

95001310 O    Cranberry, dried                   0.600000   1.000  1.000

95001320 O    Cranberry, juice                   0.600000   1.100  1.000

95001321 O    Cranberry, juice-babyfood          0.600000   1.100  1.000

04011330 4A   Cress, garden                      3.000000   1.000  1.000

04011340 4A   Cress, upland                      3.000000   1.000  1.000

09021350 9B   Cucumber                           0.500000   1.000  1.000  12

13021360 13B  Currant                            1.600000   1.000  1.000

13021370 13B  Currant, dried                     1.600000   1.000  1.000

04011380 4A   Dandelion, leaves                  3.000000   1.000  1.000

01031390 1CD  Dasheen, corm                      0.010000   1.000  1.000

13011420 13A  Dewberry                           1.600000   1.000  1.000

70001450 P    Egg, whole                         0.010000   1.000  1.000

70001451 P    Egg, whole-babyfood                0.010000   1.000  1.000

70001460 P    Egg, white                         0.010000   1.000  1.000

70001461 P    Egg, white (solids)-babyfood       0.010000   1.000  1.000

70001470 P    Egg, yolk                          0.010000   1.000  1.000

70001471 P    Egg, yolk-babyfood                 0.010000   1.000  1.000

08001480 8    Eggplant                           0.200000   1.000  1.000

13021490 13B  Elderberry                         1.600000   1.000  1.000

04011500 4A   Endive                             3.000000   1.000  1.000

04021520 4B   Fennel, Florence                   3.000000   1.000  1.000

14001550 14   Filbert                            0.100000   1.000  1.000

14001560 14   Filbert, oil                       0.100000   1.000  1.000

03001640 3    Garlic                             0.020000   1.000  1.000

03001650 3    Garlic, dried                      0.020000   1.000  1.000

03001651 3    Garlic, dried-babyfood             0.020000   1.000  1.000

01031660 1CD  Ginger                             0.010000   1.000  1.000

01031661 1CD  Ginger-babyfood                    0.010000   1.000  1.000

01031670 1CD  Ginger, dried                      0.010000   1.000  1.000

23001690 M    Goat, meat                         0.100000   1.000  1.000

23001700 M    Goat, meat byproducts              0.200000   1.000  1.000

23001710 M    Goat, fat                          0.100000   1.000  1.000

23001720 M    Goat, kidney                       0.200000   1.000  1.000

23001730 M    Goat, liver                        0.200000   1.000  1.000

13021740 13B  Gooseberry                         1.600000   1.000  1.000

95001750 O    Grape                              0.350000   1.000  1.000  13

95001760 O    Grape, juice                       0.350000   1.000  1.000  13

95001761 O    Grape, juice-babyfood              0.350000   1.000  1.000  13

95001770 O    Grape, leaves                      0.350000   1.000  1.000  13

95001780 O    Grape, raisin                      0.350000   0.900  1.000  13

95001790 O    Grape, wine and sherry             0.350000   1.000  1.000  13

10001800 10   Grapefruit                         0.500000   1.000  1.000   1

10001810 10   Grapefruit, juice                  0.500000   0.160  1.000   1

14001850 14   Hickory nut                        0.100000   1.000  1.000

09011870 9A   Honeydew melon                     0.500000   1.000  1.000

24001890 M    Horse, meat                        0.100000   1.000  1.000

13021910 13B  Huckleberry                        1.600000   1.000  1.000

05021940 5B   Kale                               1.200000   1.000  1.000

95001950 O    Kiwifruit                          0.350000   1.000  1.000

05011960 5A   Kohlrabi                           1.200000   1.000  1.000

10001970 10   Kumquat                            0.500000   1.000  1.000

03001980 3    Leek                               4.500000   1.000  1.000

10001990 10   Lemon                              0.500000   1.000  1.000

10002000 10   Lemon, juice                       0.500000   2.000  1.000

10002001 10   Lemon, juice-babyfood              0.500000   2.000  1.000

10002010 10   Lemon, peel                        0.500000   1.000  1.000

04012040 4A   Lettuce, head                      3.000000   1.000  1.000  10

04012050 4A   Lettuce, leaf                      3.000000   1.000  1.000  11

10002060 10   Lime                               0.500000   1.000  1.000

10002070 10   Lime, juice                        0.500000   2.000  1.000

10002071 10   Lime, juice-babyfood               0.500000   2.000  1.000

13012080 13A  Loganberry                         1.600000   1.000  1.000

11002100 11   Loquat                             1.000000   1.000  1.000

14002130 14   Macadamia nut                      0.100000   1.000  1.000

28002210 M    Meat, game                         0.100000   1.000  1.000

27002220 D    Milk, fat                          0.100000   1.000  1.000

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000  1.000

27012230 D    Milk, nonfat solids                0.100000   1.000  1.000

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000  1.000

27022240 D    Milk, water                        0.100000   1.000  1.000

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000  1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000

05022290 5B   Mustard greens                     1.200000   1.000  1.000

12002300 12   Nectarine                          1.200000   1.000  1.000   5

08002340 8    Okra                               0.200000   1.000  1.000

03002370 3    Onion, dry bulb                    0.020000   1.000  1.000

03002371 3    Onion, dry bulb-babyfood           0.020000   1.000  1.000

03002380 3    Onion, dry bulb, dried             0.020000   9.000  1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.020000   9.000  1.000

03002390 3    Onion, green                       4.500000   1.000  1.000

10002400 10   Orange                             0.500000   1.000  1.000   1

10002410 10   Orange, juice                      0.500000   0.160  1.000   1

10002411 10   Orange, juice-babyfood             0.500000   0.160  1.000   1

10002420 10   Orange, peel                       0.500000   1.000  1.000   1

04012480 4A   Parsley, leaves                    3.000000   1.000  1.000

06022550 6B   Pea, succulent                     0.400000   1.000  1.000

06022551 6B   Pea, succulent-babyfood            0.400000   1.000  1.000

06012570 6A   Pea, edible podded, succulent      0.600000   1.000  1.000

06022590 6B   Pea, pigeon, succulent             0.400000   1.000  1.000

12002600 12   Peach                              1.200000   1.000  1.000   5

12002601 12   Peach-babyfood                     1.200000   1.000  1.000   5

12002610 12   Peach, dried                       1.200000   2.900  1.000   5

12002611 12   Peach, dried-babyfood              1.200000   2.900  1.000   5

12002620 12   Peach, juice                       1.200000   1.000  1.000   5

12002621 12   Peach, juice-babyfood              1.200000   1.000  1.000   5

11002660 11   Pear                               1.000000   1.000  1.000   7

11002661 11   Pear-babyfood                      1.000000   1.000  1.000   7

11002670 11   Pear, dried                        1.000000   6.250  1.000   7

11002680 11   Pear, juice                        1.000000   0.880  1.000   7

11002681 11   Pear, juice-babyfood               1.000000   0.880  1.000   7

14002690 14   Pecan                              0.100000   1.000  1.000

08002700 8    Pepper, bell                       0.200000   1.000  1.000  14

08002701 8    Pepper, bell-babyfood              0.200000   1.000  1.000  14

08002710 8    Pepper, bell, dried                0.200000   1.000  1.000  14

08002711 8    Pepper, bell, dried-babyfood       0.200000   1.000  1.000  14

08002720 8    Pepper, nonbell                    0.200000   1.000  1.000  14

08002721 8    Pepper, nonbell-babyfood           0.200000   1.000  1.000  14

08002730 8    Pepper, nonbell, dried             0.200000   1.000  1.000  14

14002820 14   Pistachio                          0.100000   1.000  1.000

12002850 12   Plum                               1.200000   1.000  1.000   6

12002851 12   Plum-babyfood                      1.200000   1.000  1.000   6

12002860 12   Plum, prune, fresh                 0.200000   1.000  1.000   6

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000  1.000   6

12002870 12   Plum, prune, dried                 0.400000   2.900  1.000   6

12002871 12   Plum, prune, dried-babyfood        0.400000   2.900  1.000   6

12002880 12   Plum, prune, juice                 0.200000   1.400  1.000   6

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400  1.000   6

25002900 M    Pork, meat                         0.100000   1.000  1.000

25002901 M    Pork, meat-babyfood                0.100000   1.000  1.000

25002910 M    Pork, skin                         0.100000   1.000  1.000

25002920 M    Pork, meat byproducts              0.200000   1.000  1.000

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000  1.000

25002930 M    Pork, fat                          0.100000   1.000  1.000

25002931 M    Pork, fat-babyfood                 0.100000   1.000  1.000

25002940 M    Pork, kidney                       0.200000   1.000  1.000

25002950 M    Pork, liver                        0.200000   1.000  1.000

01032960 1C   Potato, chips                      0.010000   1.000  1.000

01032970 1C   Potato, dry (granules/ flakes)     0.010000   6.500  1.000

01032971 1C   Potato, dry (granules/ flakes)-b   0.010000   6.500  1.000

01032980 1C   Potato, flour                      0.010000   6.500  1.000

01032981 1C   Potato, flour-babyfood             0.010000   6.500  1.000

01032990 1C   Potato, tuber, w/peel              0.010000   1.000  1.000

01032991 1C   Potato, tuber, w/peel-babyfood     0.010000   1.000  1.000

01033000 1C   Potato, tuber, w/o peel            0.010000   1.000  1.000

01033001 1C   Potato, tuber, w/o peel-babyfood   0.010000   1.000  1.000

60003010 P    Poultry, other, meat               0.010000   1.000  1.000

60003020 P    Poultry, other, liver              0.050000   1.000  1.000

60003030 P    Poultry, other, meat byproducts    0.050000   1.000  1.000

60003040 P    Poultry, other, fat                0.010000   1.000  1.000

60003050 P    Poultry, other, skin               0.010000   1.000  1.000

10003070 10   Pummelo                            0.500000   1.000  1.000

09023080 9B   Pumpkin                            0.500000   1.000  1.000

09023090 9B   Pumpkin, seed                      0.500000   1.000  1.000

11003100 11   Quince                             1.000000   1.000  1.000

29003120 M    Rabbit, meat                       0.100000   1.000  1.000

04013130 4A   Radicchio                          3.000000   1.000  1.000

05023180 5B   Rape greens                        1.200000   1.000  1.000

20003190 20   Rapeseed, oil                      0.010000   1.000  1.000

20003191 20   Rapeseed, oil-babyfood             0.010000   1.000  1.000

13013200 13A  Raspberry                          1.600000   1.000  1.000

13013201 13A  Raspberry-babyfood                 1.600000   1.000  1.000

13013210 13A  Raspberry, juice                   1.600000   1.000  1.000

13013211 13A  Raspberry, juice-babyfood          1.600000   1.000  1.000

04023220 4B   Rhubarb                            3.000000   1.000  1.000

03003380 3    Shallot                            0.020000   1.000  1.000

26003390 M    Sheep, meat                        0.100000   1.000  1.000

26003391 M    Sheep, meat-babyfood               0.100000   1.000  1.000

26003400 M    Sheep, meat byproducts             0.200000   1.000  1.000

26003410 M    Sheep, fat                         0.100000   1.000  1.000

26003411 M    Sheep, fat-babyfood                0.100000   1.000  1.000

26003420 M    Sheep, kidney                      0.200000   1.000  1.000

26003430 M    Sheep, liver                       0.200000   1.000  1.000

19023540 19B  Spices, other                      0.010000   1.000  1.000

19023541 19B  Spices, other-babyfood             0.010000   1.000  1.000

04013550 4A   Spinach                            3.000000   1.000  1.000   3

04013551 4A   Spinach-babyfood                   3.000000   1.000  1.000   3

09023560 9B   Squash, summer                     0.500000   1.000  1.000  12

09023561 9B   Squash, summer-babyfood            0.500000   1.000  1.000  12

09023570 9B   Squash, winter                     0.500000   1.000  1.000  12

09023571 9B   Squash, winter-babyfood            0.500000   1.000  1.000  12

95003590 O    Strawberry                         0.600000   1.000  1.000

95003591 O    Strawberry-babyfood                0.600000   1.000  1.000

95003600 O    Strawberry, juice                  0.600000   1.000  1.000

95003601 O    Strawberry, juice-babyfood         0.600000   1.000  1.000

01033660 1CD  Sweet potato                       0.010000   1.000  1.000

01033661 1CD  Sweet potato-babyfood              0.010000   1.000  1.000

04023670 4B   Swiss chard                        3.000000   1.000  1.000

10003690 10   Tangerine                          0.500000   1.000  1.000

10003700 10   Tangerine, juice                   0.500000   2.300  1.000

01033710 1CD  Tanier, corm                       0.010000   1.000  1.000

95003720 O    Tea, dried                        50.000000   1.000  1.000

95003730 O    Tea, instant                      50.000000   1.000  1.000

08003740 8    Tomatillo                          0.200000   1.000  1.000  15

08003750 8    Tomato                             0.200000   1.000  1.000  15

08003751 8    Tomato-babyfood                    0.200000   1.000  1.000  15

08003760 8    Tomato, paste                      0.400000   3.000  1.000  15

08003761 8    Tomato, paste-babyfood             0.400000   3.000  1.000  15

08003770 8    Tomato, puree                      0.200000   1.400  1.000  15

08003771 8    Tomato, puree-babyfood             0.200000   1.400  1.000  15

08003780 8    Tomato, dried                      0.200000  14.300  1.000  15

08003781 8    Tomato, dried-babyfood             0.200000  14.300  1.000  15

08003790 8    Tomato, juice                      0.200000   1.500  1.000  15

50003820 P    Turkey, meat                       0.010000   1.000  1.000

50003821 P    Turkey, meat-babyfood              0.010000   1.000  1.000

50003830 P    Turkey, liver                      0.050000   1.000  1.000

50003831 P    Turkey, liver-babyfood             0.050000   1.000  1.000

50003840 P    Turkey, meat byproducts            0.050000   1.000  1.000

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000  1.000

50003850 P    Turkey, fat                        0.010000   1.000  1.000

50003851 P    Turkey, fat-babyfood               0.010000   1.000  1.000

50003860 P    Turkey, skin                       0.010000   1.000  1.000

50003861 P    Turkey, skin-babyfood              0.010000   1.000  1.000

01033870 1CD  Turmeric                           0.010000   1.000  1.000

05023890 5B   Turnip, greens                     1.200000   1.000  1.000

14003910 14   Walnut                             0.100000   1.000  1.000

86010000 O    Water, direct, all sources         0.020100   1.000  1.000

86020000 O    Water, indirect, all sources       0.020100   1.000  1.000

09013990 9A   Watermelon                         0.500000   1.000  1.000

09014000 9A   Watermelon, juice                  0.500000   1.000  1.000

01034060 1CD  Yam, true                          0.010000   1.000  1.000

01034070 1CD  Yam bean                           0.010000   1.000  1.000

Attachment 4.	Summary of DEEM-FCID™ Acute Results

U.S. Environmental Protection Agency                                  Ver. 2.02

DEEM-FCID ACUTE Analysis for ACETAMIPRID                         (1994-98 data)

Residue file: PRIAacetamiprid_acuteAR_2010.R98    Adjustment factor #2 NOT used.

Analysis Date: 01-14-2010/06:56:20    Residue file dated: 01-14-2010/06:49:51/8

NOEL (Acute) =  10.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 10

Run Comment: "Acute/Chronic - UFs = 100"

======================================================================== =======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  % aRfD     MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

U.S. Population:

  0.006752    6.75    1480    0.012367   12.37     808    0.023768   23.77     420

All infants:

  0.012043   12.04     830    0.020075   20.08     498    0.031227   31.23     320

Children 1-2 yrs:

  0.016770   16.77     596    0.025337   25.34     394    0.042928   42.93     232

Children 3-5 yrs:

  0.012277   12.28     814    0.020279   20.28     493    0.034282   34.28     291

Children 6-12 yrs:

  0.007509    7.51    1331    0.013299   13.30     751    0.024123   24.12     414

Youth 13-19 yrs:

  0.004686    4.69    2133    0.007810    7.81    1280    0.017682   17.68     565

Adults 20-49 yrs:

  0.004600    4.60    2173    0.007685    7.69    1301    0.015543   15.54     643

Adults 50+ yrs:

  0.004671    4.67    2140    0.007822    7.82    1278    0.013291   13.29     752

Females 13-49 yrs:

  0.004632    4.63    2158    0.007277    7.28    1374    0.013133   13.13     761

Attachment 5.	DEEM-FCID™ Chronic Residue Input File

U.S. Environmental Protection Agency                                 Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID                        1994-98 data

Residue file: C:\Documents and Settings\dmcneill\My Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

                                                               Adjust. #2 used

Analysis Date 01-12-2010             Residue file dated: 01-12-2010/08:15:02/8

Reference dose (RfD) = 0.071 mg/kg bw/day

Comment:Acute/Chronic - UFs = 100

------------------------------------------------------------------------ --------

Food Crop                                       Residue       Adj.Factors      Comment

EPA Code  Grp  Food Name                          (ppm)

                                                             #1         #2

-------- ---- -------------------------------   ---------- ------     ------   -------

14000030 14   Almond                             0.100000   1.000      1.000

14000031 14   Almond-babyfood                    0.100000   1.000      1.000

14000040 14   Almond, oil                        0.100000   1.000      1.000

14000041 14   Almond, oil-babyfood               0.100000   1.000      1.000

04010050 4A   Amaranth, leafy                    3.000000   1.000      1.000

11000070 11   Apple, fruit with peel             1.000000   1.000      0.200

11000080 11   Apple, peeled fruit                1.000000   1.000      0.200

11000081 11   Apple, peeled fruit-babyfood       1.000000   1.000      0.200

11000090 11   Apple, dried                       1.000000   8.000      0.200

11000091 11   Apple, dried-babyfood              1.000000   8.000      0.200

11000100 11   Apple, juice                       1.000000   1.300      0.200

11000101 11   Apple, juice-babyfood              1.000000   1.300      0.200

11000110 11   Apple, sauce                       1.000000   1.000      0.200

11000111 11   Apple, sauce-babyfood              1.000000   1.000      0.200

12000120 12   Apricot                            1.200000   1.000      1.000

12000121 12   Apricot-babyfood                   1.200000   1.000      1.000

12000130 12   Apricot, dried                     1.200000   6.000      1.000

12000140 12   Apricot, juice                     1.200000   1.000      1.000

12000141 12   Apricot, juice-babyfood            1.200000   1.000      1.000

01030150 1CD  Arrowroot, flour                   0.010000   1.000      1.000

01030151 1CD  Arrowroot, flour-babyfood          0.010000   1.000      1.000

01030170 1CD  Artichoke, Jerusalem               0.010000   1.000      1.000

04010180 4A   Arugula                            3.000000   1.000      1.000

09020210 9B   Balsam pear                        0.500000   1.000      1.000

06020310 6B   Bean, broad, succulent             0.400000   1.000      1.000

06020330 6B   Bean, cowpea, succulent            0.400000   1.000      1.000

06020370 6B   Bean, lima, succulent              0.400000   1.000      1.000

06010430 6A   Bean, snap, succulent              0.600000   1.000      1.000

06010431 6A   Bean, snap, succulent-babyfood     0.600000   1.000      1.000

21000440 M    Beef, meat                         0.100000   1.000      1.000

21000441 M    Beef, meat-babyfood                0.100000   1.000      1.000

21000450 M    Beef, meat, dried                  0.100000   1.920      1.000

21000460 M    Beef, meat byproducts              0.200000   1.000      1.000

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000      1.000

21000470 M    Beef, fat                          0.100000   1.000      1.000

21000471 M    Beef,fat-babyfood                  0.100000   1.000      1.000

21000480 M    Beef, kidney                       0.200000   1.000      1.000

21000490 M    Beef, liver                        0.200000   1.000      1.000

21000491 M    Beef, liver-babyfood               0.200000   1.000      1.000

13010550 13A  Blackberry                         1.600000   1.000      1.000

13010560 13A  Blackberry, juice                  1.600000   1.000      1.000

13010561 13A  Blackberry, juice-babyfood         1.600000   1.000      1.000

13020570 13B  Blueberry                          1.600000   1.000      1.000

13020571 13B  Blueberry-babyfood                 1.600000   1.000      1.000

13010580 13A  Boysenberry                        1.600000   1.000      1.000

14000590 14   Brazil nut                         0.100000   1.000      1.000

05010610 5A   Broccoli                           1.200000   1.000      0.050

05010611 5A   Broccoli-babyfood                  1.200000   1.000      0.050

05010620 5A   Broccoli, Chinese                  1.200000   1.000      1.000

05020630 5B   Broccoli raab                      1.200000   1.000      1.000

05010640 5A   Brussels sprouts                   1.200000   1.000      1.000

14000680 14   Butternut                          0.100000   1.000      1.000

05010690 5A   Cabbage                            1.200000   1.000      0.050

05020700 5B   Cabbage, Chinese, bok choy         1.200000   1.000      1.000

05010710 5A   Cabbage, Chinese, napa             1.200000   1.000      1.000

05010720 5A   Cabbage, Chinese, mustard          1.200000   1.000      1.000

09010750 9A   Cantaloupe                         0.500000   1.000      1.000

04020760 4B   Cardoon                            3.000000   1.000      1.000

09010800 9A   Casaba                             0.500000   1.000      1.000

14000810 14   Cashew                             0.100000   1.000      1.000

01030820 1CD  Cassava                            0.010000   1.000      1.000

01030821 1CD  Cassava-babyfood                   0.010000   1.000      1.000

05010830 5A   Cauliflower                        1.200000   1.000      0.100

04020850 4B   Celery                             3.000000   1.000      0.250

04020851 4B   Celery-babyfood                    3.000000   1.000      0.250

04020860 4B   Celery, juice                      3.000000   1.000      0.250

04020870 4B   Celtuce                            3.000000   1.000      1.000

09020880 9B   Chayote, fruit                     0.500000   1.000      1.000

12000900 12   Cherry                             1.200000   1.000      1.000

12000901 12   Cherry-babyfood                    1.200000   1.000      1.000

12000910 12   Cherry, juice                      1.200000   1.500      1.000

12000911 12   Cherry, juice-babyfood             1.200000   1.500      1.000

14000920 14   Chestnut                           0.100000   1.000      1.000

40000930 P    Chicken, meat                      0.010000   1.000      1.000

40000931 P    Chicken, meat-babyfood             0.010000   1.000      1.000

40000940 P    Chicken, liver                     0.050000   1.000      1.000

40000950 P    Chicken, meat byproducts           0.050000   1.000      1.000

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000      1.000

40000960 P    Chicken, fat                       0.010000   1.000      1.000

40000961 P    Chicken, fat-babyfood              0.010000   1.000      1.000

40000970 P    Chicken, skin                      0.010000   1.000      1.000

40000971 P    Chicken, skin-babyfood             0.010000   1.000      1.000

09021020 9B   Chinese waxgourd                   0.500000   1.000      1.000

19011030 19A  Chive                              4.500000   1.000      1.000

04011040 4A   Chrysanthemum, garland             3.000000   1.000      1.000

10001060 10   Citrus citron                      0.500000   1.000      1.000

10001070 10   Citrus hybrids                     0.500000   1.000      1.000

10001080 10   Citrus, oil                        0.500000   1.000      1.000

05021170 5B   Collards                           1.200000   1.000      1.000

95001280 O    Cottonseed, oil                    0.600000   1.000      0.050

95001281 O    Cottonseed, oil-babyfood           0.600000   1.000      0.050

11001290 11   Crabapple                          1.000000   1.000      1.000

95001300 O    Cranberry                          0.600000   1.000      1.000

95001301 O    Cranberry-babyfood                 0.600000   1.000      1.000

95001310 O    Cranberry, dried                   0.600000   1.000      1.000

95001320 O    Cranberry, juice                   0.600000   1.100      1.000

95001321 O    Cranberry, juice-babyfood          0.600000   1.100      1.000

04011330 4A   Cress, garden                      3.000000   1.000      1.000

04011340 4A   Cress, upland                      3.000000   1.000      1.000

09021350 9B   Cucumber                           0.500000   1.000      1.000

13021360 13B  Currant                            1.600000   1.000      1.000

13021370 13B  Currant, dried                     1.600000   1.000      1.000

04011380 4A   Dandelion, leaves                  3.000000   1.000      1.000

01031390 1CD  Dasheen, corm                      0.010000   1.000      1.000

13011420 13A  Dewberry                           1.600000   1.000      1.000

70001450 P    Egg, whole                         0.010000   1.000      1.000

70001451 P    Egg, whole-babyfood                0.010000   1.000      1.000

70001460 P    Egg, white                         0.010000   1.000      1.000

70001461 P    Egg, white (solids)-babyfood       0.010000   1.000      1.000

70001470 P    Egg, yolk                          0.010000   1.000      1.000

70001471 P    Egg, yolk-babyfood                 0.010000   1.000      1.000

08001480 8    Eggplant                           0.200000   1.000      1.000

13021490 13B  Elderberry                         1.600000   1.000      1.000

04011500 4A   Endive                             3.000000   1.000      1.000

04021520 4B   Fennel, Florence                   3.000000   1.000      1.000

14001550 14   Filbert                            0.100000   1.000      1.000

14001560 14   Filbert, oil                       0.100000   1.000      1.000

03001640 3    Garlic                             0.020000   1.000      1.000

03001650 3    Garlic, dried                      0.020000   1.000      1.000

03001651 3    Garlic, dried-babyfood             0.020000   1.000      1.000

01031660 1CD  Ginger                             0.010000   1.000      1.000

01031661 1CD  Ginger-babyfood                    0.010000   1.000      1.000

01031670 1CD  Ginger, dried                      0.010000   1.000      1.000

23001690 M    Goat, meat                         0.100000   1.000      1.000

23001700 M    Goat, meat byproducts              0.200000   1.000      1.000

23001710 M    Goat, fat                          0.100000   1.000      1.000

23001720 M    Goat, kidney                       0.200000   1.000      1.000

23001730 M    Goat, liver                        0.200000   1.000      1.000

13021740 13B  Gooseberry                         1.600000   1.000      1.000

95001750 O    Grape                              0.350000   1.000      1.000

95001760 O    Grape, juice                       0.350000   1.000      1.000

95001761 O    Grape, juice-babyfood              0.350000   1.000      1.000

95001770 O    Grape, leaves                      0.350000   1.000      1.000

95001780 O    Grape, raisin                      0.350000   0.900      1.000

95001790 O    Grape, wine and sherry             0.350000   1.000      1.000

10001800 10   Grapefruit                         0.500000   1.000      0.025

10001810 10   Grapefruit, juice                  0.500000   2.100      0.025

14001850 14   Hickory nut                        0.100000   1.000      1.000

09011870 9A   Honeydew melon                     0.500000   1.000      1.000

24001890 M    Horse, meat                        0.100000   1.000      1.000

13021910 13B  Huckleberry                        1.600000   1.000      1.000

05021940 5B   Kale                               1.200000   1.000      1.000

95001950 O    Kiwifruit                          0.350000   1.000      1.000

05011960 5A   Kohlrabi                           1.200000   1.000      1.000

10001970 10   Kumquat                            0.500000   1.000      1.000

10001990 10   Lemon                              0.500000   1.000      0.050

10002000 10   Lemon, juice                       0.500000   2.000      0.050

10002001 10   Lemon, juice-babyfood              0.500000   2.000      0.050

10002010 10   Lemon, peel                        0.500000   1.000      0.050

04012040 4A   Lettuce, head                      3.000000   1.000      0.100

04012050 4A   Lettuce, leaf                      3.000000   1.000      0.100

10002060 10   Lime                               0.500000   1.000      1.000

10002070 10   Lime, juice                        0.500000   2.000      1.000

10002071 10   Lime, juice-babyfood               0.500000   2.000      1.000

13012080 13A  Loganberry                         1.600000   1.000      1.000

11002100 11   Loquat                             1.000000   1.000      1.000

14002130 14   Macadamia nut                      0.100000   1.000      1.000

28002210 M    Meat, game                         0.100000   1.000      1.000

27002220 D    Milk, fat                          0.100000   1.000      1.000

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000      1.000

27012230 D    Milk, nonfat solids                0.100000   1.000      1.000

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000      1.000

27022240 D    Milk, water                        0.100000   1.000      1.000

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000      1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000      1.000

05022290 5B   Mustard greens                     1.200000   1.000      1.000

12002300 12   Nectarine                          1.200000   1.000      1.000

08002340 8    Okra                               0.200000   1.000      1.000

03002370 3    Onion, dry bulb                    0.020000   1.000      1.000

03002371 3    Onion, dry bulb-babyfood           0.020000   1.000      1.000

03002380 3    Onion, dry bulb, dried             0.020000   9.000      1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.020000   9.000      1.000

03002390 3    Onion, green                       4.500000   1.000      1.000

10002400 10   Orange                             0.500000   1.000      0.025

10002410 10   Orange, juice                      0.500000   1.800      0.025

10002411 10   Orange, juice-babyfood             0.500000   1.800      0.025

10002420 10   Orange, peel                       0.500000   1.000      0.025

04012480 4A   Parsley, leaves                    3.000000   1.000      1.000

06022550 6B   Pea, succulent                     0.400000   1.000      1.000

06022551 6B   Pea, succulent-babyfood            0.400000   1.000      1.000

06012570 6A   Pea, edible podded, succulent      0.600000   1.000      1.000

06022590 6B   Pea, pigeon, succulent             0.400000   1.000      1.000

12002600 12   Peach                              1.200000   1.000      0.010

12002601 12   Peach-babyfood                     1.200000   1.000      0.010

12002610 12   Peach, dried                       1.200000   7.000      0.010

12002611 12   Peach, dried-babyfood              1.200000   7.000      0.010

12002620 12   Peach, juice                       1.200000   1.000      0.010

12002621 12   Peach, juice-babyfood              1.200000   1.000      0.010

11002660 11   Pear                               1.000000   1.000      0.350

11002661 11   Pear-babyfood                      1.000000   1.000      0.350

11002670 11   Pear, dried                        1.000000   6.250      0.350

11002680 11   Pear, juice                        1.000000   1.000      0.350

11002681 11   Pear, juice-babyfood               1.000000   1.000      0.350

14002690 14   Pecan                              0.100000   1.000      1.000

08002700 8    Pepper, bell                       0.200000   1.000      0.025

08002701 8    Pepper, bell-babyfood              0.200000   1.000      0.025

08002710 8    Pepper, bell, dried                0.200000   1.000      0.025

08002711 8    Pepper, bell, dried-babyfood       0.200000   1.000      0.025

08002720 8    Pepper, nonbell                    0.200000   1.000      0.025

08002721 8    Pepper, nonbell-babyfood           0.200000   1.000      0.025

08002730 8    Pepper, nonbell, dried             0.200000   1.000      0.025

14002820 14   Pistachio                          0.100000   1.000      1.000

12002850 12   Plum                               1.200000   1.000      1.000

12002851 12   Plum-babyfood                      1.200000   1.000      1.000

12002860 12   Plum, prune, fresh                 0.200000   1.000      1.000

12002861 12   Plum, prune, fresh-babyfood        0.200000   1.000      1.000

12002870 12   Plum, prune, dried                 0.400000   1.000      1.000

12002871 12   Plum, prune, dried-babyfood        0.400000   1.000      1.000

12002880 12   Plum, prune, juice                 0.200000   1.400      1.000

12002881 12   Plum, prune, juice-babyfood        0.200000   1.400      1.000

25002900 M    Pork, meat                         0.100000   1.000      1.000

25002901 M    Pork, meat-babyfood                0.100000   1.000      1.000

25002910 M    Pork, skin                         0.100000   1.000      1.000

25002920 M    Pork, meat byproducts              0.200000   1.000      1.000

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000      1.000

25002930 M    Pork, fat                          0.100000   1.000      1.000

25002931 M    Pork, fat-babyfood                 0.100000   1.000      1.000

25002940 M    Pork, kidney                       0.200000   1.000      1.000

25002950 M    Pork, liver                        0.200000   1.000      1.000

01032960 1C   Potato, chips                      0.010000   1.000      0.025

01032970 1C   Potato, dry (granules/ flakes)     0.010000   6.500      0.025

01032971 1C   Potato, dry (granules/ flakes)-b   0.010000   6.500      0.025

01032980 1C   Potato, flour                      0.010000   6.500      0.025

01032981 1C   Potato, flour-babyfood             0.010000   6.500      0.025

01032990 1C   Potato, tuber, w/peel              0.010000   1.000      0.025

01032991 1C   Potato, tuber, w/peel-babyfood     0.010000   1.000      0.025

01033000 1C   Potato, tuber, w/o peel            0.010000   1.000      0.025

01033001 1C   Potato, tuber, w/o peel-babyfood   0.010000   1.000      0.025

60003010 P    Poultry, other, meat               0.010000   1.000      1.000

60003020 P    Poultry, other, liver              0.050000   1.000      1.000

60003030 P    Poultry, other, meat byproducts    0.050000   1.000      1.000

60003040 P    Poultry, other, fat                0.010000   1.000      1.000

60003050 P    Poultry, other, skin               0.010000   1.000      1.000

10003070 10   Pummelo                            0.500000   1.000      1.000

09023080 9B   Pumpkin                            0.500000   1.000      0.010

09023090 9B   Pumpkin, seed                      0.500000   1.000      0.010

11003100 11   Quince                             1.000000   1.000      1.000

29003120 M    Rabbit, meat                       0.100000   1.000      1.000

04013130 4A   Radicchio                          3.000000   1.000      1.000

05023180 5B   Rape greens                        1.200000   1.000      1.000

20003190 20   Rapeseed, oil                      0.010000   1.000      1.000

20003191 20   Rapeseed, oil-babyfood             0.010000   1.000      1.000

13013200 13A  Raspberry                          1.600000   1.000      1.000

13013201 13A  Raspberry-babyfood                 1.600000   1.000      1.000

13013210 13A  Raspberry, juice                   1.600000   1.000      1.000

13013211 13A  Raspberry, juice-babyfood          1.600000   1.000      1.000

04023220 4B   Rhubarb                            3.000000   1.000      1.000

03003380 3    Shallot                            0.020000   1.000      1.000

26003390 M    Sheep, meat                        0.100000   1.000      1.000

26003391 M    Sheep, meat-babyfood               0.100000   1.000      1.000

26003400 M    Sheep, meat byproducts             0.200000   1.000      1.000

26003410 M    Sheep, fat                         0.100000   1.000      1.000

26003411 M    Sheep, fat-babyfood                0.100000   1.000      1.000

26003420 M    Sheep, kidney                      0.200000   1.000      1.000

26003430 M    Sheep, liver                       0.200000   1.000      1.000

19023540 19B  Spices, other                      0.010000   1.000      1.000

19023541 19B  Spices, other-babyfood             0.010000   1.000      1.000

04013550 4A   Spinach                            3.000000   1.000      0.050

04013551 4A   Spinach-babyfood                   3.000000   1.000      0.050

09023560 9B   Squash, summer                     0.500000   1.000      0.025

09023561 9B   Squash, summer-babyfood            0.500000   1.000      0.025

09023570 9B   Squash, winter                     0.500000   1.000      0.025

09023571 9B   Squash, winter-babyfood            0.500000   1.000      0.025

95003590 O    Strawberry                         0.600000   1.000      1.000

95003591 O    Strawberry-babyfood                0.600000   1.000      1.000

95003600 O    Strawberry, juice                  0.600000   1.000      1.000

95003601 O    Strawberry, juice-babyfood         0.600000   1.000      1.000

01033660 1CD  Sweet potato                       0.010000   1.000      1.000

01033661 1CD  Sweet potato-babyfood              0.010000   1.000      1.000

04023670 4B   Swiss chard                        3.000000   1.000      1.000

10003690 10   Tangerine                          0.500000   1.000      1.000

10003700 10   Tangerine, juice                   0.500000   2.300      1.000

01033710 1CD  Tanier, corm                       0.010000   1.000      1.000

95003720 O    Tea, dried                        50.000000   1.000      1.000

95003730 O    Tea, instant                      50.000000   1.000      1.000

08003740 8    Tomatillo                          0.200000   1.000      1.000

08003750 8    Tomato                             0.200000   1.000      1.000

08003751 8    Tomato-babyfood                    0.200000   1.000      1.000

08003760 8    Tomato, paste                      0.400000   1.000      1.000

08003761 8    Tomato, paste-babyfood             0.400000   1.000      1.000

08003770 8    Tomato, puree                      0.200000   3.300      1.000

08003771 8    Tomato, puree-babyfood             0.200000   3.300      1.000

08003780 8    Tomato, dried                      0.200000  14.300      1.000

08003781 8    Tomato, dried-babyfood             0.200000  14.300      1.000

08003790 8    Tomato, juice                      0.200000   1.500      1.000

50003820 P    Turkey, meat                       0.010000   1.000      1.000

50003821 P    Turkey, meat-babyfood              0.010000   1.000      1.000

50003830 P    Turkey, liver                      0.050000   1.000      1.000

50003831 P    Turkey, liver-babyfood             0.050000   1.000      1.000

50003840 P    Turkey, meat byproducts            0.050000   1.000      1.000

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000      1.000

50003850 P    Turkey, fat                        0.010000   1.000      1.000

50003851 P    Turkey, fat-babyfood               0.010000   1.000      1.000

50003860 P    Turkey, skin                       0.010000   1.000      1.000

50003861 P    Turkey, skin-babyfood              0.010000   1.000      1.000

01033870 1CD  Turmeric                           0.010000   1.000      1.000

05023890 5B   Turnip, greens                     1.200000   1.000      1.000

14003910 14   Walnut                             0.100000   1.000      1.000

86010000 O    Water, direct, all sources         0.005000   1.000      1.000

86020000 O    Water, indirect, all sources       0.005000   1.000      1.000

09013990 9A   Watermelon                         0.500000   1.000      1.000

09014000 9A   Watermelon, juice                  0.500000   1.000      1.000

01034060 1CD  Yam, true                          0.010000   1.000      1.000

01034070 1CD  Yam bean                           0.010000   1.000      1.000

Attachment 6.	Summary of DEEM-FCID™ Chronic Results

U.S. Environmental Protection Agency                                 Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID                      (1994-98 data)

Residue file name: C:\Documents and Settings\dmcneill\My Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

                                                     Adjustment factor #2 used.

Analysis Date 01-12-2010/08:15:46     Residue file dated: 01-12-2010/08:15:02/8

Reference dose (RfD, Chronic) = .071 mg/kg bw/day

COMMENT 1: Acute/Chronic - UFs = 100

======================================================================== =======

                    Total exposure by population subgroup

------------------------------------------------------------------------ -------

                                                    Total Exposure

                                         -----------------------------------

          Population                         mg/kg             Percent of

           Subgroup                       body wt/day             Rfd

--------------------------------------   -------------       ---------------

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   0.002835                 4.0%

U.S. Population (spring season)             0.002861                 4.0%

U.S. Population (summer season)             0.003114                 4.4%

U.S. Population (autumn season)             0.002700                 3.8%

U.S. Population (winter season)             0.002660                 3.7%

Northeast region                            0.002940                 4.1%

Midwest region                              0.002864                 4.0%

Southern region                             0.002639                 3.7%

Western region                              0.003022                 4.3%

Hispanics                                   0.002916                 4.1%

Non-hispanic whites                         0.002817                 4.0%

Non-hispanic blacks                         0.002589                 3.6%

Non-hisp/non-white/non-black                0.003635                 5.1%

All infants (< 1 year)                      0.005206                 7.3%

Nursing infants                             0.002502                 3.5%

Non-nursing infants                         0.006232                 8.8%

Children 1-6  yrs                           0.008045                11.3%

Children 7-12 yrs                           0.003764                 5.3%

Females 13-19 (not preg or nursing)         0.002017                 2.8%

Females 20+ (not preg or nursing)           0.002107                 3.0%

Females 13-50 yrs                           0.002212                 3.1%

Females 13+ (preg/not nursing)              0.002362                 3.3%

Females 13+ (nursing)                       0.002580                 3.6%

Males 13-19 yrs                             0.002313                 3.3%

Males 20+ yrs                               0.002013                 2.8%

Seniors 55+                                 0.002162                 3.0%

Children 1-2 yrs                            0.010358                14.6%

Children 3-5 yrs                            0.007296                10.3%

Children 6-12 yrs                           0.004055                 5.7%

Youth 13-19 yrs                             0.002170                 3.1%

Adults 20-49 yrs                            0.002031                 2.9%

Adults 50+ yrs                              0.002130                 3.0%

Females 13-49 yrs                           0.002057                 2.9%

------------------------------------------------------------------------ -------

Acetamiprid	Dietary Exposure Assessment	DP No.: 309740

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Acetamiprid	Dietary Exposure Assessment	DP No.: 372890

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