[Federal Register Volume 79, Number 178 (Monday, September 15, 2014)]
[Rules and Regulations]
[Pages 54889-54890]
[FR Doc No: 2014-21794]

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Rules and Regulations
                                                Federal Register
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having general applicability and legal effect, most of which are keyed
to and codified in the Code of Federal Regulations, which is published
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Federal Register / Vol. 79, No. 178 / Monday, September 15, 2014 /
Rules and Regulations

DEPARTMENT OF TRANSPORTATION

Federal Aviation Administration

14 CFR Part 29

[Docket No. FAA-2014-0697; Special Conditions No. 29-034-SC]

Special Conditions: AgustaWestland, AW189; Use of 30-Minute All
Engines Operating (AEO) Power Rating

AGENCY: Federal Aviation Administration (FAA), DOT.

ACTION: Final special conditions; request for comments.

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SUMMARY: These special conditions are issued for the AgustaWestland
Model AW189 helicopter. This model helicopter will have the novel or
unusual design feature of a 30-minute all engines operating (AEO) power
rating, generally intended to be used for hovering at increased power
for search and rescue missions. The applicable airworthiness
regulations do not contain adequate or appropriate safety standards for
this design feature. These special conditions contain the additional
safety standards that the Administrator considers necessary to
establish a level of safety equivalent to that established by the
existing airworthiness standards.

DATES: The effective date of these special conditions is September 4,
2014. We must receive your comments by October 30, 2014.

ADDRESSES: Send comments identified by docket number FAA-2014-0697
using any of the following methods:
     Federal eRegulations Portal: Go to http://www.regulations.gov and follow the online instructions for sending your
comments electronically.
     Mail: Send comments to Docket Operations, M-30, U.S.
Department of Transportation (DOT), 1200 New Jersey Avenue SE., Room
W12-140, West Building Ground Floor, Washington, DC 20590-0001.
     Hand Delivery of Courier: Take comments to Docket
Operations in Room W12-140 of the West Building Ground Floor at 1200
New Jersey Avenue SE., Washington, DC, between 8 a.m., and 5 p.m.,
Monday through Friday, except Federal holidays.
     Fax: Fax comments to Docket Operations at<PHONE_NUMBER>.
    Privacy: The FAA will post all comments it receives, without
change, to http://regulations.gov, including any personal information
the commenter provides. Using the search function of the docket Web
site, anyone can find and read the electronic form of all comments
received into any FAA docket, including the name of the individual
sending the comment (or signing the comment for an association,
business, labor union, etc.). DOT's complete Privacy Act Statement can
be found in the Federal Register published on April 11, 2000 (65 FR
19477-19478), as well as at http://DocketsInfo.dot.gov.
    Docket: Background documents or comments received may be read at
http://www.regulations.gov at any time. Follow the online instructions
for accessing the docket or go to the Docket Operations in Room @12-140
of the West Building Ground Floor at 1200 New Jersey Avenue SE.,
Washington, DC, between 9 a.m., and 5 p.m., Monday through Friday,
except Federal holidays.

FOR FURTHER INFORMATION CONTACT: Eric Haight, Rotorcraft Standards
Staff, ASW-111, Rotorcraft Directorate, Aircraft Certification Service,
2601 Meacham Blvd., Fort Worth, Texas 76137; telephone<PHONE_NUMBER>;
facsimile<PHONE_NUMBER>.

SUPPLEMENTARY INFORMATION:

Reason for No Prior Notice and Comment Before Adoption

    The FAA has determined that notice and opportunity for public
comment are impractical because we do not expect substantive comments,
and because this special condition only affects this one manufacturer.
We also considered that these procedures would significantly delay the
issuance of the design approval, and thus, the delivery of the affected
helicopter. Since the public comment process would significantly delay
delivery of the AgustaWestland Model AW189 helicopter, the FAA finds
that good cause exists for making these special conditions effective
upon issuance.

Comments Invited

    While we did not precede this with a notice of proposed special
conditions, we invite interested people to take part in this rulemaking
by sending written comments, data, or views. The most helpful comments
reference a specific portion of the special conditions, explain the
reason for any recommended change, and include supporting data.
    We will consider all comments we receive by the closing date for
comments. We will consider comments filed late if it is possible to do
so without incurring expense or delay. We may change these special
conditions based on the comments we receive.

Background and Discussion

    On January 31, 2012 AgustaWestland applied for a Type Certificate
for the new model AW189. The AW189 is a Transport Category, 14 CFR part
29, twin engine conventional helicopter designed for civil operations.
This model will be certificated with Category A performance and under
both single and dual pilot instrument flight rules, powered by two
General Electric CT7-2E1 engines with a dual channel Full Authority
Digital Engine Control system, have five main rotor blades, a maximum
gross weight of 18,300 pounds, and a velocity not to exceed 169 knots.
The AW189 model will have an integrated modular avionics suite with
four 8x10 inch multi-function displays that are night vision goggle
compatible, along with a 4-axis automatic flight control system. This
helicopter will be capable of carrying a maximum of 19 passengers and 2
crew members. Its initial customer base will be offshore oil and Search
and Rescue operations.
    AgustaWestland proposes that the AW189 model use a novel and
unusual design feature, which is a 30-minute AEO power rating. 14 CFR
1.1 defines ``rated takeoff power'' as limited in use to no more than 5
minutes for takeoff operation. The use of takeoff power for 30 minutes
will require special airworthiness standards, known as special
conditions, to address the use of this 30-minute AEO rating and its
effects on the rotorcraft. The use of this power will be limited to 30
minutes. These special conditions will add requirements to the existing
airworthiness standards in 14 CFR

29.1049 (Hovering cooling test procedures), Sec.  29.1305 (Powerplant
instruments), and Sec.  29.1521 (Powerplant limitations).
    For the AW189 model helicopter, the European Aviation Safety Agency
has issued Certification Review Item E-07, which documents the special
conditions.
    The following is a summary of the final special conditions:
    (a) In addition to the requirements of Sec.  29.1049, the aircraft
cooling effects due to use of the 30-minute AEO power rating versus the
Takeoff (5-minute) rating must be accounted for in the testing.
    (b) In addition to the requirements of Sec.  29.1305, since this
new 30-minute AEO power rating has a time limit associated with its
use, the pilot must have the means to identify:
    (1) When the rated engine power level is achieved,
    (2) when the event begins,
    (3) when the time interval expires, and
    (4) when the cumulative time in one flight is reached.
    (c) In addition to the requirements of Sec.  29.1521, this new 30
minute AEO power rating must be limited to not more than 30 minutes per
use. This new rating will allow use of power above maximum continuous
power (MCP) for 30 minutes.
    (d) Furthermore, the model AW189 rotorcraft flight manual must
include limitations on use of the 30-minute AEO power rating, which
state that continuous use above MCP take-off power is limited to 30
minutes.

Type Certification Basis

    Under 14 CFR 21.17, AgustaWestland must show that the AW189 model
helicopter meets the applicable provisions of part 29, as amended by
Amendment 29-1 through 29-52, dated April 5, 2010. The model AW189
certification basis date is the May 12, 2011, date of application to
EASA.
    The Administrator has determined that the applicable airworthiness
regulations (that is, 14 CFR part 29) do not contain adequate or
appropriate safety standards for the AgustaWestland model AW189
helicopter because of a novel or unusual design feature. Therefore,
special conditions are prescribed under the provisions of 14 CFR 21.16.
    In addition to the applicable airworthiness regulations and special
conditions, the AgustaWestland model AW189 helicopter must comply with
the noise certification requirements of 14 CFR part 36; and the FAA
must issue a finding of regulatory adequacy under section 611 of Public
Law 92-574, the ``Noise Control Act of 1972.''
    The FAA issues special conditions, as defined in Sec.  11.19, in
accordance with Sec.  11.38, and they become part of the type
certification basis under Sec.  21.17(a)(2).
    Special conditions are initially applicable to the model for which
they are issued. Should the type certificate for that model be amended
later to include any other model that incorporates the same novel or
unusual design feature, the special conditions would also apply to the
other model.

Novel or Unusual Design Features

    The AgustaWestland AW189 model helicopter will incorporate the
following novel or unusual design feature:
     A 30-minute AEO power rating.

Applicability

    These special conditions are applicable to the AgustaWestland model
AW189 helicopter. Should AgustaWestland apply at a later date for an
amendment to the type certificate to include another model
incorporating the same novel or unusual design feature, the special
conditions would apply to that model as well.

Conclusion

    This action affects only certain novel or unusual design features
on one model of helicopters. It is not a rule of general applicability,
and it affects only the applicant who applied to the FAA for approval
of this feature.

List of Subjects in 14 CFR Part 29

    Aircraft, Aviation safety, Reporting and recordkeeping
requirements.

    The authority citation for these special conditions is as follows:

    Authority: 49 U.S.C. 106(g), 40113, 44701-44702, 44704.

The Special Conditions

    Accordingly, pursuant to the authority delegated to me by the
Administrator, the following special conditions are issued as part of
the type certification basis for the AgustaWestland model AW189
helicopter. Unless stated otherwise, all requirements in Sec. Sec.
29.1049, 29.1305, and 29.1521 remain unchanged.
    Section 29.1049, Hovering cooling test procedures. In addition to
the requirements of this section, for rotorcraft with a 30-minute AEO
power rating, the hovering cooling provisions at the 30-minute AEO
power rating must be shown--
    (a) At maximum weight or at the greatest weight at which the
rotorcraft can hover (if less), at sea level, with the power required
to hover but not more than the 30-minute power, in the ground effect in
still air, until at least 5 minutes after the occurrence of the highest
temperature recorded, or until the continuous time limit of the 30-
minute AEO power rating if the highest temperature recorded is not
stabilized before.
    (b) At maximum weight and at the altitude resulting in zero rate of
climb for this configuration, until at least 5 minutes after the
occurrence of the highest temperature recorded, or until the continuous
time limit of the 30-minute AEO power rating if the highest temperature
recorded is not stabilized before.
    Section 29.1305 Powerplant instruments, at Amendment 29-40. In
addition to the requirements of this section, for rotorcraft with a 30-
minute AEO power rating, a means must be provided to alert the pilot
when the engine is at the 30-minute power level, when the event begins,
when the time interval expires, and when the cumulative time in one
flight is reached.
    Section 29.1521 Powerplant limitations, at Amendment 29-41. In
addition to the requirements of this section, use of the 30-minute AEO
power must be limited to not more than 30 minutes per use. The use of
the 30-minute power must also be limited by:
    (1) The maximum rotational speed, which may not be greater than--
    (i) The maximum value determined by the rotor design; or
    (ii) The maximum value demonstrated during the type tests;
    (2) The maximum allowable turbine inlet or turbine outlet gas
temperature (for turbine engines);
    (3) The maximum allowable power or torque for each engine,
considering the power input limitations of the transmission with all
engines operating;
    (4) The maximum allowable power or torque for each engine
considering the power input limitations of the transmission with one
engine inoperative;
    (5) The time limit for the use of the power corresponding to the
limitations established in paragraphs (1) through (4) above; and
    (6) The maximum allowable engine and transmission oil temperatures,
if the time limit established in paragraph (5) above exceeds 2 minutes.

    Issued in Fort Worth, Texas, on September 4, 2014.
Lance T. Gant,
Acting Manager, Rotorcraft Directorate, Aircraft Certification Service.
[FR Doc. 2014-21794 Filed 9-12-14; 8:45 am]
BILLING CODE 4910-13-P


[Federal Register Volume 80, Number 244 (Monday, December 21, 2015)]
[Notices]
[Pages 79399-79401]
[FR Doc No: 2015-31980]

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DEPARTMENT OF TRANSPORTATION

Federal Motor Carrier Safety Administration

[FMCSA Docket No. FMCSA-2015-0066]

Qualification of Drivers; Exemption Applications; Diabetes
Mellitus

AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT

ACTION: Notice of final disposition.

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SUMMARY: FMCSA confirms its decision to exempt 54 individuals from its
rule prohibiting persons with insulin-treated diabetes mellitus (ITDM)
from operating commercial motor vehicles (CMVs) in interstate commerce.
The exemptions enable these individuals to operate CMVs in interstate
commerce.

DATES: The exemptions were effective on September 17, 2015. The
exemptions expire on September 17, 2017.

FOR FURTHER INFORMATION CONTACT: Christine A. Hydock, Chief, Medical
Programs Division,<PHONE_NUMBER><EMAIL_ADDRESS>FMCSA,
Department of Transportation, 1200 New Jersey Avenue SE., Room W64-113,
Washington, DC 20590-0001. Office hours are from 8:30 a.m. to 5 p.m.
e.t., Monday through Friday, except Federal holidays.

SUPPLEMENTARY INFORMATION:

I. Electronic Access

    You may see all the comments online through the Federal Document
Management System (FDMS) at: http://www.regulations.gov.
    Docket: For access to the docket to read background documents or
comments, go to http://www.regulations.gov and/or Room W12-140 on the
ground level of the West Building, 1200 New Jersey Avenue SE.,
Washington, DC, between 9 a.m. and 5 p.m., Monday through Friday,
except Federal holidays.
    Privacy Act: In accordance with 5 U.S.C. 553(c), DOT solicits
comments from the public to better inform its rulemaking process. DOT
posts these comments, without edit, including any personal information
the commenter provides, to www.regulations.gov, as described in the
system of records notice (DOT/ALL-14 FDMS), which can be reviewed at
www.dot.gov/privacy.

II. Background

    On August 17, 2015, FMCSA published a notice of receipt of Federal
diabetes exemption applications from 54 individuals and requested
comments from the public (80 FR 49304). The public comment period
closed on September 16, 2015, and no comments were received.
    FMCSA has evaluated the eligibility of the 54 applicants and
determined that granting the exemptions to these individuals would
achieve a level of safety equivalent to or greater than the level that
would be achieved by complying with the current regulation 49 CFR
391.41(b)(3).

Diabetes Mellitus and Driving Experience of the Applicants

    The Agency established the current requirement for diabetes in 1970
because several risk studies indicated that drivers with diabetes had a
higher rate of crash involvement than the general population. The
diabetes rule provides that ``A person is physically qualified to drive
a commercial motor vehicle if that person has no established medical
history or clinical diagnosis of diabetes mellitus currently requiring
insulin for control'' (49 CFR 391.41(b)(3)).
    FMCSA established its diabetes exemption program, based on the
Agency's July 2000 study entitled ``A Report to Congress on the
Feasibility of a Program to Qualify Individuals with Insulin-Treated
Diabetes Mellitus to Operate in Interstate Commerce as Directed by the
Transportation Act for the 21st Century.'' The report concluded that a
safe and practicable protocol to allow some drivers with ITDM to
operate CMVs is feasible. The September 3, 2003 (68 FR 52441), Federal
Register notice in conjunction with the November 8, 2005 (70 FR 67777),
Federal Register notice provides the current protocol for allowing such
drivers to operate CMVs in interstate commerce.
    These 54 applicants have had ITDM over a range of 1 to 36 years.
These applicants report no severe hypoglycemic reactions resulting in
loss of consciousness or seizure, requiring the assistance of another
person, or resulting in impaired cognitive function that occurred
without warning symptoms, in the past 12 months and no recurrent (2 or
more) severe hypoglycemic episodes in the past 5 years. In each case,
an endocrinologist verified that the driver has demonstrated a
willingness to properly monitor and manage his/her diabetes mellitus,
received education related to diabetes management, and is on a stable
insulin regimen. These drivers report no other disqualifying
conditions, including diabetes-related complications. Each meets the
vision requirement at 49 CFR 391.41(b)(10).
    The qualifications and medical condition of each applicant were
stated and discussed in detail in the August 17, 2015, Federal Register
notice and they will not be repeated in this notice.

III. Discussion of Comments

    FMCSA received no comments in this proceeding.

IV. Basis for Exemption Determination

    Under 49 U.S.C. 31136(e) and 31315, FMCSA may grant an exemption
from the diabetes requirement in 49 CFR 391.41(b)(3) if the exemption
is likely to achieve an equivalent or greater level of safety than
would be achieved without the exemption. The exemption allows the
applicants to operate CMVs in interstate commerce.
    To evaluate the effect of these exemptions on safety, FMCSA
considered medical reports about the applicants' ITDM and vision, and
reviewed the treating endocrinologists' medical opinion related to the
ability of the driver to safely operate a CMV while using insulin.
    Consequently, FMCSA finds that in each case exempting these
applicants from the diabetes requirement in 49 CFR 391.41(b)(3) is
likely to achieve a level of safety equal to that existing without the
exemption.

V. Conditions and Requirements

    The terms and conditions of the exemption will be provided to the
applicants in the exemption document and they include the following:
(1) That each individual submit a quarterly monitoring checklist
completed by the treating endocrinologist as well as an annual
checklist with a comprehensive medical evaluation; (2) that each
individual reports within 2 business days of occurrence, all episodes
of severe hypoglycemia, significant complications, or inability to
manage diabetes; also, any involvement in an accident or any other
adverse event in a CMV or personal vehicle, whether or not it is
related to an episode of hypoglycemia; (3) that each individual provide
a copy of the ophthalmologist's or optometrist's report to the medical
examiner at the time of the annual medical examination; and (4) that
each individual provide a copy of the annual medical certification to
the employer for retention in the driver's qualification file, or keep
a copy in his/her driver's qualification file if he/she is self-
employed. The driver must also have a copy of the certification when
driving, for presentation to a duly authorized Federal, State, or local
enforcement official.

VI. Conclusion

    Based upon its evaluation of the 54 exemption applications, FMCSA
exempts the following drivers from the diabetes requirement in 49 CFR
391.41(b)(10), subject to the requirements cited above 949 CFR
391.64(b)):

Joshua E. Adkins (KS)
Rosendo R. Amador (TX)
Thomas A. Ardoin (LA)
Richard L. Arsenault (TX)
George H. Bonney, Jr. (NH)
Paul M. Boucher (MI)
Tiffany C. Carvalho (MN)
Larry J. Christiansen (MN)
Cynthia J. Claunch (NM)
Stephen C. Crescentini (NJ)
John J. D'Agostino (NJ)
James R. Ditman (IN)
Eric D. Egan (IL)
Alva Eldridge (IL)
Walter R. Elser (VT)
Adam C. Exum (GA)
Ryan S. Farrell (MA)
Patrick F. Felix (WI)
Gary M. Fosnaught (PA)
Jermaine Galle (GA)
Gary A. Gross (SD)
Terry L. Guynes (MO)
Colin W. Hale (NY)
Clarence Hill (NY)
Marcus Hughes (GA)
Paul J. Lennon (IL)
Michael C. Lewis (SD)
Lon A. Mingo (MN)
Robert L. Moberly (OR)
Jason L. Montgomery (WA)
John F. Mortieau (MT)
Alexander Musalin (WA)
Clark E. Najac (NY)
Matthew S. Ness (WI)
Andrew T. Oezer (MI)
Vanja Pazin (OR)
Troy A. Pearl (WA)
Randell J. Pecenka (IA)
Leonard M. Radford (IN)
Jerry J. Rava (CA)
Isaac E. Ridenour (NM)
William J. Rixon, Jr. (NJ)
Matias Rodriguez, Jr. (CT)
William J. Schrade (CT)
John W. Schwirian (PA)
Shain L. Simpson (UT)
Neil E. Smith (KS)
Timothy R. Sobczynski (OH)
Joey F. Starnes (AL)
Joshua R. Stieb (CO)
Donald L. Strand (MT)
Rick L. Vosburg (CA)
William G. Wressell (WA)
Randy P. Young (IN)

    In accordance with 49 U.S.C. 31136(e) and 31315 each exemption is
valid for

two years unless revoked earlier by FMCSA. The exemption will be
revoked if the following occurs: (1) The person fails to comply with
the terms and conditions of the exemption; (2) the exemption has
resulted in a lower level of safety than was maintained before it was
granted; or (3) continuation of the exemption would not be consistent
with the goals and objectives of 49 U.S.C. 31136(e) and 31315. If the
exemption is still effective at the end of the 2-year period, the
person may apply to FMCSA for a renewal under procedures in effect at
that time.

    Issued on: December 9, 2015.
Larry W. Minor,
Associate Administrator for Policy.
[FR Doc. 2015-31980 Filed 12-18-15; 8:45 am]
BILLING CODE 4910-EX-P


UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D. C. 20460 OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES MEMORANDUM DATE: April 9, 2002 SUBJECT: Tebuthiuron Residue Chemistry Chapter for the Tolerance Reassessment Eligibility Decision (TRED); PC codes 105501; DP Barcode D277103.

FROM: Sheila Piper, Chemist Chemistry and Exposure Branch Health Effects Division (7509C)

THROUGH: F. B. Suhre, Branch Senior Scientist Chemistry and Exposure Branch Health Effects Division (7509C)

TO: Paula Deschamp, Risk Assessor Reregistration Branch II Health Effects Division (7509C)

and Wilhelmena Livingston, Chemical Review Manager Special Review Branch Special Review and Reregistration Division (7508C)

The Tolerance Reassessment Eligibility Document (TRED) for tebuthiuron has undergone secondary review in the branch and has been revised to reflect Agency policies.

cc: S. Piper (CEB), RF RDI: ChemSAC: 3/ 27/ 02: Secondary Reviewers: 3/ 27/ 02: F. B. Suhre 4/ 8/ 02 7509C: CEB: CM 2: RM 810F: 308 2717: Tebuthiuron 2 N N S N CH 3 CH 3 C H 3 C H 3 O N H CH 3 TEBUTHIURON INTRODUCTION Tebuthiuron [N[ 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N, N' dimethylurea] is a relatively nonselective, soil activated herbicide registered for use to control broadleaf, woody weeds, grasses, and brush on terrestrial feed crop sites (pastures and rangeland) primarily in TX, OK, and NM. Tebuthiuron is also used on terrestrial non food crop such as airports/ landing fields, industrial areas, non agricultural rights of way, fencerows, hedgerows, and non agricultural uncultivated areas/ soil; there is no agricultural crop use of tebuthiuron except for range and pasture land uses. Pelleted/ tablets (P/ T) is the only tebuthiuron formulation class registered for use on food/ feed crops. The registered mode of application is broadcast using ground or aerial equipment (Source: LUIS General Chemical Report for Tebuthiuron, 5/ 20/ 92). There are no registered residential uses.

GLN 860.1000: REGULATORY BACKGROUND Tolerances for residues of tebuthiuron have been established for grasses and animal commodities [40 CFR §180.390]. These tolerances are expressed in terms of the combined residues of N[ 5 (1, 1diemethylethyl) 1, 3, 4 thiadiazol 2 yl] N, N' dimethylurea and its metabolites containing the dimethylethyl thiadiazole moiety. Adequate enforcement methods are available for the determination of residues in/ on grasses and in animal tissues and milk.

Tebuthiuron was first registered by Elanco Products Company in 1974. The registration was later transferred to DowElanco (currently Dow AgroSciences LLC) in 1989. The Tebuthiuron Reregistration Standard Guidance Document was issued 7/ 87 for all pesticide products containing the active ingredient, tebuthiuron. The information contained in this document outlines the Residue Chemistry Science Assessments with respect to the reregistration of tebuthiuron.

The summaries of residue chemistry guidelines and topics listed below are based on the present regulatory status where the only registered food/ feed use of tebuthiuron is on grasses grown in pasture and rangeland. The Agency reserves the right to require additional studies for each applicable residue chemistry guideline and topic if additional registrations on food/ feed crops other than pasture and rangeland grasses are sought, or if a tolerance change is proposed. 3 N N S N CH 3 CH 3 C H 3 O N H CH 3 OH N N S NH 2 CH 3 C H 3 C H 3 N N S N CH 3 CH 3 C H 3 C H 3 O NH 2 N N S N CH 3 CH 3 C H 3 C H 3 O N H OH N N S N CH 3 CH 3 C H 3 O NH 2 OH N N S N CH 3 CH 3 C H 3 O N H OH OH N N S N H CH 3 C H 3 C H 3 O NH 2 Figure A. The chemical structures of the metabolites of concern of tebuthiuron Structure Metabolite: Chemical name Structure Metabolite: Chemical name 103 (OH): N[ 5( 2 hydroxy 1,1 dimethylethyl) 1,3, 4 thiadiazol 2 yl] N, N' dimethylurea 108: 2 dimethylethyl 5 amino 1, 3, 4 thiadiazole 104: N[ 5( 1,1 dimethylethyl) 1,3, 4 thiadiazol 2 yl N methylurea 109: N[ 5( 1,1 dimethylethyl) 1,3, 4 thiadiazol 2 yl N' hydroxymethyl N methylurea 104 (OH): N[ 5( 2 hydroxy 1,1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N methylurea A [109 (OH)]: N[ 5( 2 hydroxy 1,1 dimethylethyl 1,3,4 thiadiazol 2 yl] N' hydroxymethyl N methylurea 106: N[ 5( 1,1 dimethylethyl) 1,3, 4 thiadiazol 2 yl] urea 4 SUMMARY OF SCIENCE FINDINGS GLN 860.1200: Directions for Use Based on a search of OPP's REFs conducted on March 22, 2002, there are eight active Section 3 registrations for end use products containing tebuthiuron. End use formulations include granular, pelleted/ tablets, and wettable powder products which are applied using ground and aerial equipment. A summary of the currently registered end use products and use sites is given in the Table 1 below:

Table 1: Current registered end use products and use sites Company EPA Reg. No. Formulation Class % ai Use Sites Rainbow Technology Corp 13283 18 Granular 2 Industrial areas (outdoor) Non agricultural rights of way/ fencerows/ hedgerows 13283 21 Granular 1 Industrial areas (outdoor) Non agricultural rights of way/ fencerows/ hedgerows SSI Maxim Company, Inc. 34913 10 Granular 5 Drainage systems Non agricultural uncultivated areas/ soils 34913 15 Granular 1 Non agricultural uncultivated areas/ soils 34913 16 Granular 2 Non agricultural uncultivated areas/ soils Dow AgroSciences LLC 62719 107 Wettable Powder 80 Drainage systems Non agricultural uncultivated areas/ soils 62719 121 Pelleted/ Tableted 20 Pasture/ rangeland Non agricultural uncultivated areas/ soils 62719 122 Pelleted/ Tableted 40 Pasture/ rangeland Non agricultural uncultivated areas/ soils The 20% and 40% P/ T formulations (EPA Reg. Nos. 62719 121 and 62719 122, dated 2/ 96) are registered for a single broadcast application to rangeland and forage grasses by aerial or ground equipment at 0. 5 4. 00 lb ai/ A. Tebuthiuron may be applied anytime but the recommended timing of application is prior to the resumption of active seasonal growth in the spring or before expected seasonal rainfall. The maximum recommended rate is 4.0 lb ai/ A for areas receiving >20 inches average annual rainfall, or 2.0 lb ai/ A for areas receiving <20 inches average annual rainfall. Application to ditches used to transport irrigation or potable water is prohibited. 1 MARC members (C. Olinger, L. Cheng, R. Loranger and D. Nixon) determined the residues of concern in the tolerance expression should also be included in the risk assessment.

5 GLN 860.1300: Nature of the Residue Plants The qualitative nature of the residue in grasses is adequately understood. The registrant (1976; MRID 00020756) submitted a "revised" metabolism study in which a [ 14 C] tebuthiuron solution (labeled in the 5 position of the thiadiazole ring; specific activity of 16. 9 uCi/ mg) was applied to the surface of the soil in which 10 week old tall fescue (0.374 lb ai/ A), little bluestem and indiangrass (0.75 lb ai/ A.) were grown. The residues of concern are the parent compound and its metabolites 103 (OH), 104, and 109 (N. Dodd, MRIDs 40985001 02, 6/ 22/ 89). MARC 1 revisited N. Dodd's memo, "Nature of the Residue in Milk and Bovine Tissues," dated 6/ 22/ 89 and determined the parent compound and its metabolites 103 (OH), 104, and 109 should also be included in the risk assessment (3/ 28/ 02).

Tebuthiuron was the most abundant 14 C residue recovered in the organosoluble fraction of the grass extract. Other metabolites identified in the organosoluble fraction from all three grass species were 103( OH), 104, and 109. Approximately 39 86% of the total 14 C activity of all grasses was identified from the organosoluble fraction. The metabolites which were recovered and identified following acid hydrolysis of the aqueous fraction were 103( OH), 104, and l04( OH). The predominant conjugate in little bluestem was 103( OH) while 104 was the major conjugate in indiangrass. One additional metabolite, isopropyl 103, was found in the hydrolysates of the aqueous fraction of little bluestem. Based on the 14 C residues identified in the organosoluble and aqueous fractions, approximately 81 89, 58 70, and 78 80% of the total 14 C activity found in tall fescue, little bluestem, and indiangrass, respectively, was identified. In summary, two major metabolic pathways are involved: N demethylation of tebuthiuron to form 104 and alkyl hydroxylation of the dimethylethyl side chain to form 103( OH). The molecular structures of the metabolites of concern are presented in Figure A.

GLN 860.1300: Nature of the Residue Livestock The qualitative nature of the residue in milk and ruminant tissues is adequately understood. The terminal residues of concern in fat, meat, kidney, and liver are tebuthiuron and its metabolites 104, 106, 108, and 109; the terminal residues of concern in milk are tebuthiuron and metabolites 104, 104 (OH), 106, 109, and A [109 (OH)] for the tolerance expression and risk assessment (N. Dodd, MRIDs 409850 02, 6/ 22/ 89). A poultry metabolism study is not required since grasses are not considered to be poultry feed items.

A metabolism study was conducted on one cow in the study titled "Nature of [ 14 C] Tebuthiuron Residues in Bovine Tissue" (J. D. Magnussen and D. P. Rainey, Ph. D., Experiment ABC0413, Lilly Research Laboratories, January 24, 1989, MRID No. 409850 02). Capsules containing [ 14 C] tebuthiuron labeled in the 5 position of the thiadiazole ring were placed directly into the rumen via a surgically fitted fistula. The 280 kg (approximately) cow was given one capsule every 6 12 hours (morning and evening) for 3 consecutive days. Each capsule contained 140 mg [ 14 C] tebuthiuron, which the petitioner has calculated to be a feeding rate of 50 ppm. The cow was sacrificed 12 hours after the final dose. The percentage of the total radioactivity which was identified was 82.7 percent in fat, 87.2 percent in lean, 83.2 percent in liver, and 91.0 percent in kidney. Of the total radioactivity in milk, 64. 2 to 68. 1 percent was not conjugated (i. e., extractable in acetonitrile or ethyl acetate). Between 25.4 and 29.6 percent were conjugated (i. e., polar). Most of the conjugated residues were released by enzyme or acid hydrolysis. Residues in milk (days 1, 2, and 3) as a percentage of total radioactivity were reported as follows: 1. 1 to 1. 2 percent, parent (103); 20.7 to 21.6 percent, 104; 21.0 to 26.3 percent, 106; 10.0 to 11.8 percent, 109; 2.2 to 3. 2 percent, 108; 1.0 to 1. 7 percent, 103( OH); 9. 6 to 16.3 percent, 104( OH); 7. 6 to 11.8 percent, Metabolite A or 109( OH); 1. 5 to 7.2 percent, Metabolite B; 1. 7 to 2.5 percent, Metabolite C; and 3. 3 to 5. 5 percent, other. The molecular structures of the metabolites of concern are presented in Figure A.

GLN 860.1340: Residue Analytical Methods  Plants and Livestock An adequate method is available for the enforcement of plant commodity tolerances. A GLC method with flame photometric detection is designated as Method II in PAM Vol. II. Tebuthiuron and metabolites 104 and 109 are thermally degraded on the GLC column and are determined as 5( 1, 1 dimethylethyl) N methyl 1, 3, 4 thiadiazol 2 amine; metabolite 103 (OH) is determined as 5( 2 hydroxy 1, 1 dimethylethyl) N methyl 1, 3, 4 thiadiazol 2 amine. The stated detection limits are 0. 1 ppm for tebuthiuron and metabolites 104 and 109, and 0. 2 ppm for metabolite 103 (OH). A revised enforcement method for milk, to include hydrolysis steps and the determination of metabolites 104 (OH) and A [109 (OH)], and a revised enforcement method for animal tissues, to include hydrolysis steps and the determination of metabolite 108, were submitted.

GLN 860.1380: Storage Stability The available storage stability data indicate that residues of tebuthiuron and its metabolites containing the thiadiazole moiety [103 (OH), 104, and 109] are stable for up to ca. 29 months of frozen storage at 20 C in/ on grass forage and hay. Tebuthiuron and its metabolites 104, 104( OH), 109, 109( OH), and 106 are stable in milk stored frozen for up to 6 months. These data are translated to meat and stability data for metabolite 108 (not found in milk) will not be required. The stability data fully support the ruminant feeding study and no additional data are required (S. Funk, D223089, 11/ 22/ 95). 7 GLN 860.1400: Water, Fish and Irrigated Crops Tebuthiuron is presently not registered for direct use on potable water and aquatic food and feed crops; therefore, no residue chemistry data are required under these guideline topics.

GLN 860.1460: Food Handling Tebuthiuron is presently not registered for use in food handling establishments; therefore, no residue chemistry data are required under these guideline topics.

GLN 860.1480: Magnitude of the Residue in Meat, Milk, Poultry and Eggs The reregistration requirements for data depicting magnitude of the residue in milk, eggs, and livestock tissues are fulfilled. The registrant submitted animal feeding study to reassess the adequacy of established tebuthiuron tolerances on animal commodities. A summary of the animal feeding data relative to the maximum theoretical dietary burden of tebuthiuron to beef cattle and dairy cattle are included in this document.

Maximum Theoretical Dietary Burden An acceptable ruminant feeding study (S. Funk, D217379, 12/ 05/ 95) has been submitted. The results of the ruminant feeding study conducted at a nominal 45 ppm tebuthiuron feeding level (1. 5x) for 28 days show that the existing tolerances for milk and meat are inadequate and that they should be revised. The tolerances for meat and fat may be lowered, but the tolerances for milk and meat byproducts must be increased as follows:

Commodity Existing Tolerance 1 (40 CFR § 180.390) Revised Tolerance 1 Milk 0. 3 0. 8 Ruminant 2 ,fat 2 1. 0 Ruminant 2 , mbyp 2 5.0 Ruminant 2 , meat 2 1.0 1 The tolerance is expressed in terms of tebuthiuron and its metabolites containing the dimethyethyl thiadiazole moiety. 2 Separate tolerances are established for cattle, goats, horses, and sheep.

The feeding study have demonstrated a transfer of tebuthiuron to livestock tissue (meat, meat byproducts etc.). A dietary burden reflecting theoretical maximum exposures to tebuthiuron for 8 beef cattle (extrapolating to goats, sheep and horse) was based on reevaluated tolerances for grass forage and grass hay, 10 ppm each.

Table 2: Maximum Ruminant Dietary Burden for Tebuthiuron Commodity Tolerance (ppm) %DM a Beef Cattle Dairy Cattle %Diet a Concentration b (ppm) %Diet a Concentration b (ppm)

Grass Forage 10 25 60 24 60 24 Grass Hay 10 88 60 40 4.5 60 40 4.5 TOTAL   100 28.5 100 28.5 a As per Table 1 (OPPTS Guideline 860.1000) b Ruminant contribution= [tolerance/ %DM] x %diet No poultry or swine feed items are associated with the registered uses on grass; therefore, there is no reasonable expectation of detectable residues of tebuthiuron and its metabolites in poultry, swine, and eggs resulting from the use patterns being considered for reregistration. These uses for poultry, swine, and eggs can be classified under Category 3 of 40 CFR§ 180.6( a).

GLN 860.1500: Magnitude of the Residue in Plants The 20% and 40% P/ T formulations (EPA Reg. Nos. 62719 121 and 62719 122, dated 8/ 12/ 91) are registered for a single broadcast application to rangeland and forage grasses by ground or air equipment at 0. 5 4. 00 lb ai/ A. Tebuthiuron may be applied anytime but the recommended timing of application is prior to the resumption of active seasonal growth in the spring or before expected seasonal rainfall. The maximum recommended rate is 4.0 lb ai/ A for areas receiving  20 inches average annual rainfall, or 2.0 lb ai/ A for areas receiving  20 inches average annual rainfall. Fresh grass samples were collected every two weeks for the first three months following application, and monthly for the following twenty one months in order to determine the maximum residue level that may occur at anytime following application. Hay samples were collected up to two years following the application. The maximum combined residues found in/ on grass forage were  9.5 ppm and < 8.0 ppm for hay samples (collected after the first cutting in the following season and then after the next two cuttings). Application to ditches used to transport irrigation or potable water is prohibited. Treated grasses may not be cut for hay for livestock feed for one year after treatment. The Agency considers restrictions against the grazing of treated rangeland to be impractical, and label revision is required. 9 Currently, HED's OPP Guidelines 860.1000 supports a 0 day crop field residue data for grasses cut for grass forage and a reasonable interval before cutting for hay. Tebuthiuron was not sampled at a 0 day time point in the forage grass residue study because sample timing was driven by formulation and use pattern considerations. Spike is an extruded pellet containing either 20% or 40% active ingredient. The pellets settle into the grass and plant litter and are difficult to find and essentially unavailable from a residue point of view. On bare ground there would be approximately 1 pellet per square foot per pound of a. i. applied. Residues do not appear in plants until the pellets have been activated by rainfall and the active ingredient washed into surface soil where it is taken up by plants (preferable until 0.5 inches of rainfall had occurred). The registrant adjusted the sampling schedule within the test area reflecting the maximum residue levels occurring at any time after application were tested (N. Dodd, DEB No. 4587, 2/ 9/ 89).

HED supports the registrant hay residue study protocol and specifically allowed hay sampling to begin 1 year after application. Spike 20P and 40P are used only for woody plant infestation (trees and brush). This will allow re vegetation with desirable grasses, but also because the sparse grass in such areas do not provide adequate nutritional levels for grazing or hay in that first year (N. Dodd, Tebuthiuron on Grass and Hay, Memorandum of Conference 4/ 6/ 89).

All data requirements for the magnitude of the residue in plants have been evaluated and deemed acceptable. The conclusions regarding the reregistration eligibility of tebuthiuron on the crops listed in Table A are based on the use patterns registered by the basic producer, Dow AgroSciences LLC. When end use product DCIs are developed (e. g., at issuance of the RED), RD should require that all end use product labels (e. g. MAI labels, SLNs and products subject to the generic data exemption) be amended such that they are consistent with the basic producer labels.

GLN 860.1520: Processed Food/ Feed No processed food/ feed studies were submitted by the registrant.

GLNs 860.1850/ 1900: Confined/ Field Rotational Crops Grasses in rangeland are not rotated. Pastures on the other hand can vary from permanent (> 8 years), short term (2 4 years), long term (5 8 years), as well as temporary (< 1 year). A rotational pasture is one used for a few seasons and then plowed and planted to another crop. 10 The Quantitative Usage Analysis for Tebuthiuron indicates that the states with the most acres treated are in the Southwest U. S. (TX, OK, NM, and AZ). The grassland areas covered by these states include the Southern Plains and the Southwest Grasslands. These grassland areas are predominately rangeland that contains perennial native or introduced grasses, that have been invaded by woody perennial weedy shrubs which are very difficult to control. Pastures are mostly perennial grasses or legumes; however, we do not know if there are any significant pasture acreage planted to annual forages in this region.

Therefore, confined field rotational crop studies will be conditionally required unless the registrant can provide information that pastureland in this area is either insignificant in acreage or is predominantly perennial grasses that are not rotated annually. 11 Table A. Range and Pasture Typical and Maximum Use Rates Use Site and Product Name Application Method and Equipment Registrant Maximum Application For Use Rate Parameters Label Maximum Application Per Use Registrant Typical Use Rate Reflecting Label Typical Use Rate Range and Pasture Spike 20P (20% pellet) Broadcast and spot treatment Applied by hand using canister delivery, ground and aerial application For vulnerable sites, maximum application rate is dependent upon annual precipitation:

<20" in annual precipitation: no more than 1 lb a. i./ acre once every 3 years >20" in annual precipitation: no more than 2 lbs a. i./ acre once every 3 years For non vulnerable sites, maximum application rate is dependent upon annual precipitation:

<20" in annual precipitation no more than 2 lbs once every 3 years and no more than two treatments totaling 6 lbs a. i./ acre in any 6year period.

>20" in annual precipitation: no more than 4 lbs a. i./ acre once every 3 years and no more than two treatments totaling 6 lbs a. i./ acre in any 6 year period For broadcast treatment, 4 lbs a. i./ acre For spot treatment when needed, 6 lbs a. i./ acre Typical application is once every 10 20 years 1.0 1.4 lbs for oak use 1. 5 lbs for desert species 0.3 0.5 lbs for sage NS (continued; footnotes follow) 12 TABLE B. RESIDUE CHEMISTRY SCIENCE ASSESSMENTS FOR REREGISTRATION OF TEBUTHIURON.

GLN Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? References 1 860.1300: Plant Metabolism No 2 00020645, 00020756, 00020766 860.1300: Animal Metabolism No 00020648, 00020650, 00020651, 00020652, 00020721, 00020767, 00027805, 00027810, 00041675, 00106080, 40985001 40985002 3 860.1340: Residue Analytical Methods See footnote 4 00020656, 00020740, 00041673, 00094745, 00106080, PP# 7F1925, 41196901 5 , 43983701 4 , 43983702 4 860.1380: Storage Stability No 6 42630501 7 , 43439301 6 860.1500: Magnitude of the Residue in Plants Grass Forage, Fodder, and Hay Group Grass, forage 10 No 00020757, 00020764, 00041671, 00094745, 42630502 7 Grass, hay 10 No 00020705, 00094745, 42630502 7 860.1520: Magnitude of the Residue in Processed Food/ Feed N/ A 860.1480: Magnitude of the Residue in Meat, Milk, Poultry, and Eggs No 8 00041673, 00106080 860.1400: Magnitude of the Residue in Fish N/ A 860.1400: Nature and Magnitude of the Residue in Drinking and Irrigation Water N/ A 860.1460: Magnitude of the Residue in Food Handling Establishments N/ A 860.1550: Reduction of Residues N/ A 860.1850: Rotational Crops (Confined) See footnote 9 TABLE B. (continued).

GLN Data Requirements Current Tolerances, ppm [40 CFR] Must Additional Data Be Submitted? References 1 13 1. Unless otherwise noted, references were reviewed in the Residue Chemistry Science Chapter of the Reregistration Standard dated 2/ 27/ 87.

2. CBRS No. 2959, 12/ 10/ 87, N. Dodd.

3. CBRS No. 4939, 6/ 22/ 89, N. Dodd.

4. Enforcement methods for milk and animal tissues have been proposed; independent laboratory validation is required. The registrant submitted submission MRIDs 43983701 02 which is under reviewed.

5. Data pertaining to multiresidue methodology testing of tebuthiuron and metabolites has been submitted and forwarded to FDA for review (M. Nelson to L. Sawyer, 9/ 1/ 89).

6. The stability data fully supports the ruminant feeding study, and no additional data are required (S. Funk, CBRS 16937, 11/ 22/ 95).

7. CBRS No. 11314, D187699, 5/ 20/ 93, S. Funk.

8. An adequate feeding study has been submitted (S. Funk, D217379, 12/ 95).

9. The confined field rotational crop studies will be conditionally required unless the registrant can provide information that pastureland in TX, OK, and NM is either insignificant in acreage or is predominantly perennial grasses that are not rotated annually. 860.1900: Rotational Crops (Field) See footnote 9 14 TOLERANCE REASSESSMENT SUMMARY HED has concluded that the tolerance expression for plants should include tebuthiuron and its metabolites N[ 5( 2 hydroxy 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N, N' dimethylurea [103 (OH)], N[ 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N methylurea (104), and N[ 5( 1, 1dimethylethyl 1, 3, 4 thiadiazol 2 yl] N' hydroxymethyl N methylurea (109).

The tolerance expression for livestock commodities should include tebuthiuron and its metabolites 104, N[ 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] urea (106), 2 dimethylethyl 5 amino 1,3,4 thiadiazole (108), and 109. The terminal residues of concern in milk are tebuthiuron and metabolites 104, N[ 5( 2 hydroxy 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N methylurea [104( OH)], 106, 109, and N[ 5( 2 hydroxy 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N'hydroxymethyl N methylurea [109( OH)].

The adequacy of the established tolerances for milk, and the fat, meat, and meat byproducts of cattle, goats, hogs, horses, and sheep were from the results of the ruminant feeding study conducted at a nominal 45 ppm tebuthiuron feeding level (1. 5x) for 28 days (S. Funk, D217379, 12/ 05/ 95). The existing tolerances for milk (0. 3 ppm) and meat byproducts (2 ppm) should be increased to 0. 8 ppm for milk and 5 ppm for meat byproducts. The tolerance for meat (2 ppm) and fat (2 ppm) should be lowered to 1 ppm.

Table C. Tolerance Reassessment Summary Commodity Current Tolerance (ppm) Tolerance Reassessment (ppm) Correct Commodity Definition Cattle, fat 2 1 Cattle, mbyp 2 5 Cattle, meat 2 1 Goats, fat 2 1 Goats, mbyp 2 5 Goats, meat 2 1 Horses, fat 2 1 Horses, mbyp 2 5 Horses, meat 2 1 Milk 0. 3 0. 8 Sheep, fat 2 1 Sheep, mbyp 2 5 Sheep, meat 2 1 HED recommends that the 40 CFR tolerance expression under §180.390 be modified as follows: 15 § 180.390 Tebuthiuron; tolerances for residues (a) Tolerances are established for the combined residues of the herbicide tebuthiuron N 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl N, N' dimethylurea) and its metabolites N[ 5 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N methylurea, N[ 5( 1, 1 dimethylethyl) 1, 3, 4thiadiazol 2 yl] urea, 2 dimethylethyl 5 amino 1,3,4 thiadiazole, and N[ 5( 1, 1dimethylethyl 1, 3, 4 thiadiazol 2 yl] N' hydroxymethyl N methylurea in or on the following raw agricultural commodities:

Commodity Parts per million Cattle, fat 1 Cattle, mbyp 5 Cattle, meat 1 Goats, fat 1 Goats, mbyp 5 Goats, meat 1 Horses, fat 1 Horses, mbyp 5 Horses, meat 1 Sheep, fat 1 Sheep, mbyp 5 Sheep, meat 1 (b) A tolerance is established for the combined residues of the herbicide tebuthiuron N 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl N, N' dimethylurea) and its metabolites N[ 5 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N methylurea, N[ 5( 2 hydroxy 1, 1dimethylethyl 1, 3, 4 thiadiazol 2 yl] N methylurea, N[ 5( 1, 1 dimethylethyl) 1, 3, 4thiadiazol 2 yl] urea, N[ 5( 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N' hydroxymethyl Ndimethylurea and N[ 5( 2 hydroxy 1, 1 dimethylethyl) 1, 3, 4 thiadiazol 2 yl] N'hydroxymethyl N methylurea in or on the following raw agricultural commodity:

Commodity Parts per million Milk 0. 8 16 DIETARY EXPOSURE ASSESSMENT A refined acute and chronic dietary exposure assessment was conducted for tebuthiuron registered for foliar application to pastures and rangeland (secondary transfer to livestock commodities). Anticipated residues from field trial data and percent crop treated were utilized to estimate the dietary exposure to tebuthiuron in the diets of the U. S. Population (chronic) and females 13 50 years (acute only) [S. Piper, D281821, 04/ 2/ 02].

CODEX HARMONIZATION No Codex MRLs have been established or proposed for residues of tebuthiuron. Therefore, issues of compatibility with respect to U. S. tolerances and Codex MRLs do not exist. 17 AGENCY MEMORANDA CITED IN THIS DOCUMENT CBRS No.: 2959 Subject: EPA Registration No. 1471 101 (RCB No. 2959)  Data Waiver or Amendment Requested and Protocol Re: Tebuthiuron Reregistration (No Accession Number) From: N. Dodd To: R. Taylor and Toxicology Branch Dated: 12/ 10/ 87 MRID( s): None CBRS No.: None Subject: Tebuthiuron on Rangelands and Pastures Protocol for Magnitude of Residues Studies for Tebuthiuron Reregistration (No Accession Number) From: N. Dodd To: R. Taylor, Toxicology Branch II Dated: 2/ 9/ 89 MRID( s): None CBRS No.: None Subject:[ Multiresidue methodology testing of tebuthiuron and six of its metabolites.] From: M. Nelson To: L. Sawyer, FDA Dated: 9/ 1/ 89 MRID( s): 41196901 CBRS No. : 4939 Subject: EPA Registration No. 1471 101 (DEB No. 4939)  Tebuthiuron Reregistration  Nature of the Residue in Milk and Bovine Tissues. From: N. Dodd To: R. Taylor and Toxicology Branch II Dated: 6/ 22/ 89 MRID( s): 409850 01 and 409850 02.

CBRS No.: 11235 DP Barcode: D187084 Subject: Tebuthiuron: Waiver Request for Grazing Study and Grazing Study Protocol; Draft of Enforcement Analytical Method for Milk; Schedule for Meat and Milk Analytical Methods; Schedule for Feeding Study. From: S. Funk To: P. Perreault Dated: 2/ 9/ 93 MRID( s): None 18 CBRS No.: 11314 DP Barcode: D187699 Subject: Tebuthiuron: List A; Chemical 105501; Case 0054. DowElanco Response to the Registration Standard Data Requirements for Grass Field Trials (171 4( k)) and Storage Stability for Forage and Hay (171 4( e)). MRID Nos. 42630501 and 42630502. From: S. Funk To: L. Rossi/ L. Propst Dated: 5/ 20/ 93 MRID( s): 42630501 and 42630502 CBRS No.: 15883 DP Barcode: D217379 Subject: Tebuthiuron: Ruminant Feeding Study (171 4 (j)). From: S. Funk To: L. Propst/ K. Rothwell Dated: 12/ 5/ 95 MRID( s): 43703201 CBRS No.: 16937 DP Barcode: D223089 Subject: Tebuthiuron Storage Stability in Support of the Ruminant Feeding Study (171 4( e; j)). From: S. Funk To: P. Deschamp Dated: 8/ 1/ 96 MRID( s): 43439301 CBRS No.: None DP Barcode: D281821 Subject: Tebuthiuron Acute and Chronic Dietary Exposure Assessments for the Tolerance Reassessment Eligibility Decision (TRED). From: S. Piper To: P. Deschamp/ W. Livingston Dated: 4/ 2/ 02 MRID( s): None