Hey everybody, welcome back to another exciting episode of A Week in Geekdom. Invisible Geo here, you can just see my hand right there. We're doing another haul video for the month of April. This is actually pretty interesting because I kinda went a little crazy in some areas. Unfortunately a massive package of books did not arrive but there's still some good stuff here that I can geek out over you guys can enjoy and if you want me to review any of that stuff, leave those comments down below. As always, remember to like, comment, subscribe and help with the YouTube algorithm and all that nonsense. We're gonna start a little bit out of order. I'm not a huge amiibo collector but I got this bad boy, the Banjo-Kazooie amiibo. I don't really collect the line. I just have Joker, the hero, a couple Metroids, Toon Link and this bad boy. That's it. Let's get out of the way. Let's get into manga because I know that you guys like to see the manga haul, right? Not a whole lot. Like I mentioned earlier, big package, not arrived, containing a lot of cool stuff that came out in the month of April that a lot of people are excited to read. But I did get some stuff that I'm excited to check out, right? And that's what matters. Let's start with Viz, manga from Viz Media. Here we have Myer Academia Volume 27, looking really awesome. I love this cover. Here we see the back. Another one of my favorites here is Dr. Stone Volume 16, looking really awesome.  I absolutely love it. That's the stuff I want to read when I check out Dr. Stone. Here we have Demon Slayer Volume 21. There are two more volumes away from ending this whole thing. I actually have been waiting patiently to read this physically so I don't know how the series ends. I've avoided spoilers so far, so yay me. So yeah, this volume was really awesome, all the fights and stuff. Really enjoyed that. And a new series for me at least because this was released a while back. I saw Volume 2 at my nearest Walmart and thought, you know what? Why not? I'll get it. It's something I've been wanting to collect. I love manga based on video games so I went ahead and picked up Legend of Zelda, Twilight Princess, Volume 2 and ordered this right away from the seller on eBay, I believe, for dirt cheap. Really excited to dig into this looking really awesome. Really going to enjoy reading Twilight Princess in manga format. Only one Viz Media Hardcover manga arrived. Next month you should see a lot more, unfortunately, just the one book. And it is Sunny from Taya Matsumoto, Volume 2, that awesome finish and construction of that book and that wonderful art. Really excited about this. Now I can probably read it because last time I showed you Volume 1 and Volume 3. So now I can go ahead and get started on this series and make a proper review video for the channel about Sunny. So let's take this out and load it up with more manga. This time, last haul, I showed you that I got into the famous world of Gants and this is no exception. I picked up the rest of the Omni-Editions, the Omnibus. So that's Volume 4 and Volume 5 right there. I am still missing Volume 2, which is still out of stock as of the recording of this video and I did pre-order Volume 6, which comes out late May 2021. But nonetheless, I'm really excited about it. Like I mentioned in the previous haul videos, I know what happens in all of Gants. That was spoiled to me, but this will be my first read through for the actual series. Hopefully I don't show something that's too nuts for work, but these monster dinos look really, really badass. I don't mind the big chunky additions. I prefer it that way, to be honest. I know a lot of people would prefer oversized hardcover treatment and all that stuff, but I'm good with that. Next up, a classic from Makoto Yugi Mura. This is something that I've been wanting to check out for a while. It's a shame that the anime is not available on Blu-ray because that's something that I also want to own for my collection. But here is the, I believe there are also omnibus additions of Planets. Here's Volume 1 and let's put it over here. And here is Volume 2. I said that right, Planets, right? Probably not, because it's me. I will probably review this at some point because I'm trying to beef out the review sections for Manga in this channel and cover sort of like the famous works, if you will. So yeah, look forward to this sometime soon.  Well, yeah, that's not going to fit. Here's Berserk, Deluxe Edition Volume 7. This is a chunky boy, and as you can see, wonderful artwork, wonderful panels, wonderful story. I've already read all of this, but it's so cool to see it in oversized format in all its bloody, morbid glory from Kantarumi Yuda. So yeah, Berserk, Deluxe Edition Volume 7. So that's it for the manga. Let me show you a couple anime. There's two movies. A couple months ago, I picked up Violet Evergarden, the complete series. So I found for cheap the movie, Violet Evergarden, Eternity, and the Auto Memory Doll, right there. Unfortunately, I do not have the digital code on that one, so I do apologize. I usually like to give those away, but this was a pre-owned copy. And last but not least, I know, trust me, I know. It's not the greatest movie, but I already own all of the Studio Ghibli stuff on Blu-ray, so I had to do it as well and get Earwig and the Witch.  And like, Goto Miyazaki should just stay away from making these movies or whatnot. But hey, I mean, they're doing something that I wish I could do. I wish I could create a movie and all that stuff. But nonetheless, I like the character designs. Not the animation per se, but it's all right. You know, it's not the best, but you know, I've seen worse. So that's it for anime. Let's see what else. All right. Let's take these off and show you guys real time because I do get graphic novels, comics, all that fun stuff. Here is a recommendation from my buddy OmniDogs, Sarah, and the Royal Stars from Vault Comics. I have no idea what this is about, but he said it was awesome and that I would like it. And yeah, it looks really cool. I have not read it yet. But here is, again, the cover for Volume 1. Does it fit here? It does not. Yay. And here is the cover for Volume 2. Originally, I wasn't going to get it, but then again, it completes the trilogy and I can finish off that series. It is Wonder Woman Earth 1 Volume 3 from Grant Morrison and Yannick Paquette and Nathan Faradbearn. This is, I think I have one video on this on the first volume on this channel. It's a reimagining set in Earth 1 of the DC continuity. It's a different Earth than the main one that you're used to. So Wonder Woman and everybody else acts totally different, but kind of similar. But yeah, here is the finale of that series with Volume 3.  I can't wait to read this to see how it ends. I stopped at the beginning of Hell on Earth, so now I can do a proper read-through and check out all of the main stories of BPRD. All right, guys. I went a little crazy, aside from all the fun stuff that you just saw. I went a little nuts when it comes to video games. I've made a realization. I don't really care about the Xbox Series X, S, Y, W, whatever you want to call it. I don't really care about the PlayStation 5. I'm content being a Nintendo Switch collector. So I went through some YouTube videos of different retro gamers, modern gamers, any gamer, I don't know, and they were listing their favorite Switch games in their collections, showing off the physical media. That's what I like, physical media. Even though I do get digital games, but for the most part, 95% of my collection is all physical. Yeah, I went a little bit crazy, added a bunch of titles there. The list is still there.  That's a lot of games, for my budget at least. But here is all that fun stuff. Here we have the Shantae collection with the slip covers released by Limited Run Games. I don't have all the Shantae games, I'm missing one, but this is really cool. So yeah, love the artwork on this. Here on the spine, you see the five different games that have been released, the logo right there, and inside are four of the games, which I'll show you right now. I mean, I've already, a couple months back, I showed you that I already owned these two. But the new additions, along with the slip cover, is of course the original Shantae for the Game Boy Color, remastered or ported over to the Switch, I guess. Right here is Shantae, Risky's Revenge Director's Cut. I believe this was a DSi wear game, correct me if I'm wrong on that. The only game I'm missing is Pirate's Curse, which came out on the Vita, I think, 3DS and Switch. That is ridiculously expensive online, going from 80, and that's even lucky. If you're lucky enough, I should say, to find it for 80 bucks to like 130, 150, something like that for the entire, for the game, I should say. So yeah, $35 game when it came out, I guess, for the Switch, not going to spend $150 for that. Hopefully, because we did get a reprint for the fourth game, hopefully it happens and we get Pirate's Curse on, you know, a second printing, I guess, of that game. Alright, so let's go through this stack of Switch games from the oldest to the latest. Alright, let's see. First we have Hades from Supergiant. This game's amazing. I'm terrible at it, but it's amazing. I love it. I die pretty quickly and I'm pretty terrible playing it, but I have fun, regardless. I already had this digitally and I double dipped.  The pamphlet with character artwork, they haven't released a heart cover of the art of Hades, but this is the next best thing. And probably when they release the art book. I'll be getting that as well. Let's move Shantae over there. This is a game in a series that I really like, but I've never owned. I played it on PS2. I played even the mobile games. It is Katamari Damacy Reroll, PS1 classic that I finally own again. I remember owning it and playing it on my original PlayStation. The Spyro Reignited Trilogy. I've only played the first one, never played the second and third games, so I'm really excited about that. Now this next game, I love arcade games, shooters, the fighting games, beat-em-ups. I love action platformers and all that fun stuff. That's usually where I spend most of my time when I'm playing video games and your Nintendo stuff and what not, the original IPs and what not. But one of the other things I really like is pinball. On my Switch, I have pinball FX3 with all the tables and all that stuff. And that's sufficient for what I want. However, I had to get the Stern Pinball arcade for the Switch because Stern Pinball, you know, they're the head honchos with a lot of mula and they're not going to appear at the pinball FX3. So I wanted to play their classic tables such as Star Trek, Mustang, Harley Davidson, Last Action Hero, Mary Shelley's Frankenstein, stuff like that, which it's emblematic of Stern Pinball. Now the one thing, because you might be thinking, well, you should get it digitally to match with the FX3 and that's true. But I kind of wanted this because of the ACDC table. They lost the license for it digitally and the only way you can play that table on your console is by getting the physical edition, whether it's Nintendo Switch, PlayStation 4 or Xbox One or whatever it may be, you can only play that physically. So I had to get it. This is an indie game. It looked interesting, looked really cool, found it for a really cheap price. It is Owl Boy. I love the cover on that. So I'm looking forward to playing this. This is something that I've always wanted to play for years. I played, I'm gonna admit it, I played a rom of it in high school or, yeah, high school, yeah, it's been a while folks. And I always wanted to own the games and I was close to getting them for the DS, but I remembered that this was available on the Asian market. So I got this from Play Asia, imported it. It is the Ace Attorney 123 collection. So I'm really excited to own this and there's a new one coming out that I already have pre-ordered. So it'll go great with this. So my birthday last year, 2020. One of the things I wanted to get were the Mega Man Legacy Collections. I already had Mega Man 11. So I wanted to get every Mega Man game available for the Switch. So of course I got Mega Man 11, got the Legacy Collections. And I've had to get this. I was missing the Mega Man Zero ZX Legacy Collection. Really cool. I wasn't gonna fetch the GBA prices complete in box online. So I went ahead and picked this up instead. This is a recent limited run order. It's really cool that this already shipped because we're so used to the delays and waiting so long for pre-orders from limited run and all that stuff. So it was really nice to see the notification that it shipped. And this was made available back in January. It is the Scott Pilgrim versus the World of Video Game, the complete edition. Really cool. I only ordered the base set, you know, comes with the little card, the concert ticket and the manual, all that fun stuff. Oh, and of course, reversible cover right there. Look at that. I prefer this one. Classic homage to Sonic Adventure. And last but not least, another one of those classic arcade games that I've always wanted to own in some shape or form. This is a classic of the arcade era. It is the Dragon's Lair Trilogy on Switch. I wanted to get this on PS2, skipped on it. I wanted to get it on, I think that we had an edition of it, skipped it. And there were like two more editions I can't remember right now. So I settled on the Switch edition because yeah, like I said, I'm collecting for the Switch. I'm really happy about this. I'm probably never going to own an original arcade. Arcade One Up has the Dragon's Lair Trilogy cabinet that they're coming up with. I ain't got room for that. So I'm just happy with this. Also, if you go the ROM route is really difficult to emulate, depends on what you're doing. And yeah, not gonna go that route. So with that Nintendo background there, that's the end of the haul. Like I said, I was missing actually three shipments from Right Stuff with a ton of manga and anime. So you'll see that in the next haul video. But let me know what you thought if you want me to review any of the manga and anime and all that stuff that I featured on this haul video. Let me know in the comment section down below. And of course, it wouldn't be a haul video without some bloopers. And I actually remembered, I forgot to highlight, one of the biggest purchases I've made this year so far. There it is guys, the Oculus Quest 2. Yeah, I've been wanting to get this for a year and a half as of this video. I remember bothering my dad constantly about all the VR stuff. And I really wanted to get into this. I love the idea, I love virtual reality. And this has not disappointed. I've only had it for a week as of this video and it's been so much fun. I've had a blast with this, just playing the random games, all the freebies. I actually got some games and I actually do wanna make more videos on this thing. Not on this channel, maybe on my second gaming channel. The link is in the description below. So yeah, this has been a lot of fun. Thank you guys so much for being a part of a week in geekdom, subscribing, commenting, all that fun stuff. If you're new here, I do content like this where I talk about all the hauls and of course going over anime, comics and manga reviews. So if you wanna help a brother out and subscribe and help out with the algorithm and all that stuff, I would very much appreciate it. That's it for me, I've gotta go. God bless, stay safe out there. I will catch all of you on our next video.


So my name is Bing Zhang. I'm a professor of molecular and human genetics in the Baylor College of Medicine in Houston, Texas in the United States. So I'm a PI of a lab of about 10 people. So our focus is on computational biology with application to studying cancer. So my lab is supported by funding primarily from the National Institute of Health and we're currently applying integrative bioinformatics methods to the understanding of cancer and try to figure out better ways to treat cancer. I think there are probably two aspects of this. First, I think people have to understand the need. So why we need to do the integration. I think there should be some demonstration project to demonstrate that there is a value to integrate the data. And I think some of the government effort, for example the CPTAC effort in the U.S. is doing something like this to try to bring people together and demonstrating the value of by integrating genomic and the proteomic data. For example, we can learn something that we won't be able to learn by looking at the data separately. I think then we can get some papers published for example and then people will appreciate the value of this. And the second part is, I mean, even if you want to integrate, you need to have the ability to integrate the data, right? I think currently this is through integration, interaction between scientists with different types of expertise. But I think in the future we also need to think about education. Our next generation scientist should be able to at least understand both genomic data, proteomics data, etc. And also can understand the computational part and the experimental part so that they have a holistic view of the biology and then they can do much better job than what we can do today. Well, I think basically these are basic technologies and the whole genome sequencing technology is trying to study the DNA sequences and the transcriptomic sequencing are trying to study the transcribed mRNAs. I would rather also through in the proteomics part, which will study the protein, which is a translated product of the genes. People sometimes ask me, I mean, which one is a better technology? Which one do you like? To me, I think a better way is to integrate all these technologies. Again, I mean, we want to get a holistic view of the system and the way to do that is by analyzing the system at different molecular levels, if you can, and then using informatics approach to integrate this data and this will give us the better view of the system and better understand of the disease if you want to study certain type of diseases. I think the cis EQTLs and trans EQTLs, they are not exclusive, actually a lot of times they are the same or they are connected. Let's think about a transcription factor. If there is a QTL in the promoter region of the transcription factor, it will be cis EQTL because as sleep in that region will affect the expression of the transcription factor itself. But because the transcription factor itself alter the expression will change the activity of the transcription factor and then it will change a lot of downstream genes regulated by the transcription factor. In that way, the sleep will also be a trans EQTL. So, a lot of times we can use the cis EQTL to identify the genes that are potentially important, but the trans EQTL can also tell us what is the downstream regulatory network that this sleep is working on. So, I think they are actually connected, they could be connected. So, I think that is actually a very fun part of our research. I think bioinformatics as a research area, one thing we are doing is to try to develop algorithms and methods in order to solve problems, but eventually what we want to do is to solve the biological problems. We want to make the biologists who don't have the ability to program, for example, to have access to the tools. So, a lot of efforts in my lab have been spent on this direction. So, basically we develop web-based applications so that through very user-friendly interface people can have access to a huge amount of data and then they can also have appropriate tools that they can directly use to analyze those data. One example is a linked omics tool we recently published. I think it has been used by, it has started to get many users from the cancer research community. Yeah, I think it's really interesting part of the research to make your tools or methods directly available to biologists. Actually, most of the protein interaction network data we can have or the protein interaction data we can have today in the public data repositories, I would think most of them are the static or more stable interaction relationship rather than the transient interaction relationships. I would hope that more experiments can be done in this area that can help us to identify the transient interactions and then condition-specific interactions and then we can better annotate the network and the interactions within the network and then we can use the right network to interpret our data in the right conditions. So I think it's not that we already have a lot of transient interactions in the data that but it's I think we just have very few of those interactions and we need add more but of course we need good annotations in the database to let people know about that so that they can identify the right interaction network for the specific condition they're interested in. I think the primary protein sequence can provide a lot of information that you can use to predict protein-protein interaction but the studies have shown that and only use that information you won't be able to reach very high prediction accuracy. Leveraging other type of data can certainly improve the prediction accuracy and I also want to mention that the technology like the deep learning and this more advanced machine learning technologies that are available today because of both the software and the hardware improvements now can enable us to better predict the protein interaction for example based on the primary sequence but still and if we can incorporate more other type of data that can certainly improve your prediction accuracy and especially when you want to predict the condition specific interaction I don't think the primary sequence can give you a lot of information on that and for that part specifically you want to incorporate more information. That is true on most of the databases even the protein interaction database and the entities in those databases are actually genes when we talk about protein-protein interaction the protein interaction database we're actually talking about the gene level data and I think the challenge is not the database itself is gene centric I think it's we just don't have enough information to distinguish the function and the interaction and the characteristic of the individual protein isoforms. Again I think in the future I hope the protein the databases can be protein isoform centric because different isoform can actually have very different functions but in order to achieve that and for example the proteomics experiments the sequence coverage has to be improved a lot because currently if you do a math back based experiment the sequence coverage is actually pretty no it's less than 10 percent could be and with that you won't be able to very well distinguish the different protein isoforms that's why the interpretation is usually done as at the gene level it's not difficult to and converts the protein level data to gene level you because it's aggregated to the gene level right but I think it's more difficult to get the detailed data as the protein isoform level and the build database centered around the protein isoforms rather than genes. My name is Karsten Kug. I'm a computational scientist at the proteomics platform of the Proto Institute of MIT in Harvard and I'm interested in how we can integrate large-scale data sets that have been acquired using different omics technologies. In the gene centric analysis we study the gene or the gene product itself so meaning we want to compare its expression between two phenotypes. Let's say in the context of cancer we want to know whether a gene is specifically upregulated in a cancer compared to a normal tissue which would probably or potentially introduce a new target for this for this specific cancer. If we study the entirety of all genes or gene products in the cell we have to perform a statistical test which tells us which genes or proteins are statistically significant between human normal samples and we would end up with long lists of differentially expressed genes which are sometimes very difficult to interpret. So in order to better understand what is happening and for example tumors on a molecular level we would usually or typically map these proteins or genes to pathways in order to better understand what is dysregulated in these tumors on a molecular level. There are many different or several different databases that facilitate this kind of analysis so there is the reactant database, there is the CAC database or also the database of molecular signatures or MCDB. So if you ask me whether gene centric analysis or pathway centric analysis is better so I personally think that both types of analysis are equally important so sometimes a gene centric analysis alone will probably cannot give you the correct answer because the gene that you are interested in is probably not necessarily statistically significant or it's only like a marginal case but if you look at a specific pathways and several members of these pathways are going into the same direction in the tumor sample for example which so this gives you more evidence that this pathway is regulated for example. So we know that many many mutations, millions of mutations have been associated to certain diseases and phenotypes but only for a very few we know actually the molecular consequences that are being introduced by these mutations. So if a mutation affects a coding region of a gene so it might be a non-synonymous meaning it can introduce an amino acid change in the corresponding protein sequence and if we think about post-translational modifications like phosphorylation of serine, thionine and tyrosines this can actually affect these these phosphorylation sites. So serines, thionines and tyrosines are actually very abundant in the human proteome and therefore it's very likely that these amino acids are affected by mutations. So very or probably the simplest case of like the impact of a mutation of on phosphorylation sites is that a phosphorylation site now gets mutated into a different amino acid so meaning it cannot be phosphorylated anymore and we so it's very crucial to understand what kind of downstream effects these kinds of events have. Like in case a mutation affects a modified amino acid like a serine that is usually phosphorylated now the serine is being mutated into a different amino acid it cannot be phosphorylated anymore so and it would it's very crucial to understand what kind of downstream effects are introduced by these kinds of mutations. So this is probably the the most simplest form of such events other forms of these events can must not necessarily directly affecting the PTM site but they can be happening in very close proximity and for example in phosphorylation we know we very well know the enzymes that are responsible for phosphorylation kinases and phosphatases kinases which are phosphorylating their substrates are recognizing a very specific stretch of amino acid that surrounds the PTM site so this is one of many mechanisms how a kinase recognizes its substrates so the kinase usually has between a couple and a hundred substrate and so these amino acid stretches around these PTM sites as one mechanism how a kinase recognizes its substrates so if a mutation now changes the amino acid composition of these flanking sequences as we call them around these PTM site has direct effect on the kinase substrate binding specificity so it might happen that a phosphocyte that has been more phosphorylated by specific kinase like AKD-1 for example can now not be phosphorylated anymore by this particular kinase because it cannot recognize its substrate site anymore so on the other hand or like another more complex example would be if the kinase recognition motif now changes from a kinase A to kinase B so the wild type form the unmuted form the phosphocyte was was phosphorylated by a certain kinase and now after the mutation the kinase recognition motif fits better to another kinase which now can go and phosphorylate this phosphorylation site so all of these events are probably not well understood as of now and I think it's very important to learn and to study these kind of events more in detail I think phosphorylation by far is the best and most studious post translation modifications to date because we have the methods to study these in phosphorylation on a large scale there's other post translation modifications like ubiquitination or lysine acetylation which now we also have the methods to study those at large scale or some patient samples of course we can very easily study whether mutation effects directly these PDM sites like whether these lysines are being replaced by another amino acid and now these lysines cannot be ubiquitinated or acetylated anymore but I think we still have very limited knowledge about specific binding motifs for a lot of these acetyltransferases for example so there are specific examples that when we know the sequence motif when we talk about histone modifications for example but our knowledge is still very limited in this regard I think what is very important for a biologist is to be able to at least partially analyze their own data so now biology has moved away from you know hypothesis-driven a very targeted type of analysis or experiments more to like a data-driven omics type of experiments so the amount of data is on a completely different scale compared to 10 years or 15 years back so even as a wet lab biologist it's very important to be able to analyze your own data so you need to have some computational skills I think an easy way I think okay I think an easy way to get started with any computational analysis or data science driven analysis are scripting languages like R or Python for example so both of these languages are very popular and very heavily used in data science and in general but also in computational biology in particular I can only highly recommend any student who studies biology to get some skillset in R or Python


Llyrgrifwsredig yn du. Ieil barserio'r me全nid comisiolaidd gyngergwadorell y cyfrybcylus neu gynnwys mwr Five missions, gan felly mae'n Faceitlu na'IG sporting. felly mae'n bwysig, gwend当然aidd gyisiaeth Downing iawn cael ei gw Eig Fsigar. Wrth gwrtodau hyn, mae返wyr yn ei gweld yn agl maith bod iranod y mae cyhöad yn吗? The committee wishes to take items 4, 5 and 6 in private. Thank you very much. Agenda item 2 is correspondence. It is considered correspondence from the Public Audit and Post Legislative Scrutiny Committee. The Public Audit Committee has asked all committees, for example, of any major, recurring themes that are present during committee scrutiny. One theme that we have discussed previously is that the committee could suggest is the need for the Scottish Government and the UK Government to work very closely together to deliver devolved social security. Does the committee agree to respond to the audit committee on those lines? Thank you very much. We are now moving to private session, agenda item 3, the child poverty bill.


Okay, so the development of Plasma 6 has started quite some time ago actually, but of course we're just at the beginning and there's not much of interest to see. But nonetheless, I had to try out the current state of the Plasma 6 branch anyway since I'm, you know, a KD developer and also I thought that I would share with you how it went. However, it's a journey both for me and for you and you will not get to see Plasma 6 before I do. And believe me, there's a lot of things to do before that. So let's start. Today I try to build Plasma 6. Now, how does this work usually? KD projects hosted on GitLab have a branch called Master, that is, you know, the very latest. However, with the switch to Qt6, some KD projects have split their development in the development branches into the Qt5 branch called KF5 or similar and the Qt6 branch actually called Master or similar. This hasn't happened for all projects since it started with the KD frameworks where the 6 works started and only somewhat recently it got to Plasma projects as well. So what did I do back when this happened? Well, there's a script called ksrcbuild which builds KD projects and I went to its config settings and I added use the branch called KF5 Qt5 which basically forced the script to always use the Qt5 branch whenever there was one. So I've been basically missing out from anything with a 6 until today. I created a new folder called KD6 where to build Plasma 6. I created a new config file in that folder which was basically the same one but with 6 instead of 5 everywhere. And then I told KDE source build, hey, sexy, can you start building? The poor thing actually tried to do something before screaming at me through error logs that I had forgotten to install Qt6. Okay, fair enough. I installed Qt6 Dev packages, I try again and the poor thing starts screaming again that I installed Qt6.2 instead of Qt6.4 which is required. And here's the issue, I'm using Ubuntu Studio 22.04. The latest Qt packages are only on Ubuntu 23.04 called Lunar Lobster which hasn't released yet. So I did something, I did something bad that you should never ever do. I opened the ATCAPT sources.list file and I added one line with the Lunar package repositories. This basically allows me to install Lunar packages on a non-Lunar system, however mixing packages from different major versions of Ubuntu is basically asking for problems but sometimes it works so I gave it a shot. I had to figure out the correct packages to install but it kind of worked. I managed to start building stuff and then I spent the couple of hours trying to fix little missing dependencies and such until one of the project asked me to install the latest version of some kind of Qt framework library that for some reason is not on Qt's githlab. I'm confused here. I mean, as a no big deal I can just install it through the package manager again of Lunar. And apt told me that it was going to download half of a gigabyte of Lunar packages which is way more than I would like to mix with my non-Lunar packages. But whatever, we only live once I guess. So I went with it and everything broke, boom. I spent the following half an hour where any command that required apt would just end with a giant wall of text of errors saying you held broken packages and thanks I know that apt. Worst thing using apt fix missing install which is what you're supposed to do gave me an error because of OBS somehow trying to upgrade that one package for forced OBS to also upgrade and that didn't work. So I removed OBS because I'm such a professional developer. That worked kind of. It also removed the telegram desktop client from my system. I don't know why it just happened. So okay, I go on on building packages until I get another error. I'm missing some files related to Qt6 Swayland. I reinstalled every single Qt6 Swayland package and yet nothing happens. It's almost as if the Qt6 Swayland package was broken itself which obviously can't happen because it was shipped by Ubuntu and they know more than I know. So I went to the KD development chat and I kindly asked everybody, hey, what's up with this? And apparently Ubuntu is refusing to package some files of the Qt6 Swayland package because of reasons. Kindly enough a fellow developer sent me on telegram which I had just reinstalled through a snap the missing files which I just copy pasted. Meaning that now my packages are a mix of 22.04 packages, 23.04 packages and copy pasted from telegram packages. Now I don't want to say that Ubuntu is a bad operating system at all. After all there hasn't been a single time where I hadn't issues with ABT. But had I been using Fedora, probably this would have been so much easier. But it's on me, lol. At this point of the story it has already been 3 hours and I decided to go to sleep. I ate you of my trying to even just build KD Plasma 6 challenge and yes, I managed to. As you might have guessed, yesterday I recorded the first part of the video before actually being able to build Plasma 6 and today I managed. But it wasn't at the press of a button because there has been one last big issue that has stumped me for hours. Today I wake up, I tell KD Sirs to build everything and it fails on KWallet. I go check the error logs and apparently I am missing a library called QCA which is necessary for KWallet. Which is weird because QCA is made by KDE and I had just build QCA and QCA did build successfully so I had no idea what was up with KWallet and I just said you know what, just forget it. I ignored it and told KD Sirs build to just build KD Plasma Desktop and that also failed because Plasma Desktop depends on KWallet. So if I want KD Plasma Desktop, I need KWallet which needs QCA, which I do have weirdly enough. Now here's the thing, it's failing on QCA QT6 whereas I normally build QCA QT5 obviously. However as I explained I did tell KD Sirs build to please use QT6 so I don't know what was up with that. I searched in the documentation of Plasma 6 for the QCA QT6 and yes the documentation does tell me to install QCA QT6 as a package from the package manager. On Arch Linux, I am not on Arch Linux, I am on Ubuntu which does not have any QCA QT6 packages. So I did the best thing I could do which is to send a private message to the KD developer who wrote the documentation talking about Plasma 6 and I told him about my problem. And I gave up, I started working on other stuff. After I don't know like 6 hours I told myself, Nikola you have to solve the QCA QT6 problem or you won't be able to record a YouTube video which would be terrible. So I had an idea, I went to the Arch Linux repository, now this story could now end terribly because as you know my system is a mix of old Ubuntu, new Ubuntu, telegram Ubuntu and the only way to make these voices to somehow use the Arch repositories on Ubuntu but no I had a better idea. Arch Linux has the source files of their packages which do include a file showing how they were built. By looking at them, I do see that they are building QCA with the option KF6 QT6 just like I'm doing but nonetheless I try to do it manually and I see that something is going wrong. The files that are being generated even though I specifically asked KF6 QT6 are still QT5.  In the various building options that I ignored simply because they weren't relevant to me on the Arch Linux page, there's one that's actually quite important which is DQT6 on. Try to guess what it does, seriously just try to guess what on hurt the option called QT6 equals on is going to do. What is it? What does it do? So yeah, I copy-pasted that and it just worked. The mystery is not yet fully solved because in theory KD source build should have done it for me, so I went back to the documentation about building Plasma 6 and I noticed that I'm a double idiot, kinda. So I had set up KD source build by using the template for QT6 on the documentation but there was actually another way to do that which is manually and if you do it manually you have this little instruction that tells you to enable the CMIC flag equals a D build with QT6 equals on. Somehow this flag is instead missing in the template I was given and just by adding that flag to the template, everything worked. So maybe who wrote that template just missed it, happens. So just 15 minutes later I finally built Plasma 6 and now here's the moment of truth. Will it run? And yes, it does. So here it is. This is Plasma 6, built by me. So please take a moment to appreciate the fact that you've been listening to, I don't know, 10 minutes of rambling about building something that looks exactly like Plasma 5 or at least that should look exactly like Plasma 5. There are some bugs which is quite obvious given that this is early, early work in progress. However some of them are pretty funny. As an example my panel now has three kickoff icons, the one on the left is actually kickoff, whereas the two on the right, if clicked, will immediately crash Plasma. Look, I told you, it's still work in progress. So what else? Well, all context menus look like this which is not Breeze. And as soon as I open any window it looks like this, which is also not Breeze. This makes me think that I somehow messed up building Breeze and that the system is failing back to Oxygen, which is pretty funny. I will take some time to fix that, just not today. So what else? Is everything working? The ad widgets sidebar is missing icons, which, okay. And the activity switcher is also missing desktop previews, which I think it should have. Note that this is not my way to report bugs, I'm just talking about these things for fun. I will also make sure to raise my issues if I can confirm that they're not my fault in the appropriate places, don't worry. And don't take this video as how Plasma 6 is going to be, not at all. It's more of a yes, development has started. Nicolò, if Plasma 6 right now looks exactly like Plasma 5 but with more bugs, why did you spend two days building it? There's nothing to try out anyway. Now, as I told you, the code repositories of KDE currently have Qt6 and Qt5 branches, some of them, I mean. The thing is that the Qt5 branches are technically in visual freeze, if I understood it correctly, meaning that you cannot add anything new to them. But I do want to add features. And to do that, I have to make merge requests to the Qt6 branches, which does not require actually running Plasma 6, unless I also want to try out the features which I'm proposing, which is essential. So there's also other people proposing new features that require me to work on the master branch. Before today, I just couldn't test those ones. I was just able to look at the code, but now I can actually build those proposals and try them out. Yes, I'm using a teleprompter. Try them out in Plasma 6. So the simple answer is that yes, Plasma 6 development has started, and thus I have to start using Plasma 6 sometimes, because I am a KDE developer. I want to be at least. You might have another final question. Niccolò, if Plasma 6 right now is so boring, why did you make an entire video about it with a clickbaited title and everything? And here's the thing. I don't actually get paid by KDE. I'm doing all of this in my free time. And the only way for me to have money to eat and everything, whilst still having lots of time for KDE, is to receive donations and at revenue. If you watch an ad to see this video, you are contributing to Plasma 6 development. Does that feel good? If not, you can directly donate to also contribute in a more direct way to my involvement in Plasma 6, because yes, right now it looks like Plasma 5, but hey, that's gonna change. And I'm trying to do my part and I need your help too. So thanks everybody who's helping out and following my journey and see you soon with new and exciting, hopefully devlogs.


So, a little more than a month ago, we talked about Torteghida. This is one of the activists trying to stop the construction of Cop City, Atlanta. But during a raid on January 18th by police, Torteghida was shot and killed by police. But because of the autopsy, we're learning that activists were right to doubt the initial police narrative because it does indeed seem as if Torteghida had their hands up when they were shot and killed. This explains, the stop Cop City activist who was shot dead by Georgia police earlier this year was likely sitting cross-legged on the ground with their hands raised when gunfire from multiple officers struck them at close range, according to an independent autopsy. Lawyers for the family of 26-year-old Manuel Esteban Payees-Taren, known as Torteghida, released the results of that autopsy in a press conference Monday. The report also showed they were shot at least 14 times, including in the face. The independent autopsy results cast additional doubt on the police's narrative, which was that they acted in self-defense after Torteghida shot an officer in the leg. Quote, they were shot so many times and by different firearms that the tracks running through the body converge and intersect, said Brian Spears, one of the lawyers representing Torteghida's family. Manuel was looking death in the face hands raised when killed. Torteghida was killed by Georgia State Patrol on the morning of January 18th as officers attempted to clear the encampment at the site of the proposed training center. The police went to the force that morning planning for violence said lawyer Jeff Philippovitz. It was a planned operation yet no one had a body camera when they shot Manuel. So this is an absolute bombshell. This evidence completely dismantles the police narrative, but it's not really that surprising. There was a reason to doubt the official narrative coming from Georgia police and anyone who was skeptical is proven right by this. Now I want to give you some additional context. We did cover this back on I believe January 24th and this video that I'm about to play for you is my additional coverage of Cop City. What it is, why Torteghida was protesting it and why activists in the area were doubtful of the police narrative. Let's watch. I want to talk about a story that is truly at the intersection of so many issues environmentalism, indigenous peoples rights, police militarization and the overpolicing of majority black cities, the American police state, so on and so forth. That story is Cop City. Now fortunately, people are finally starting to pay attention to Cop City, but the heightened awareness of Cop City comes at the expense of one activist's life. Manuel Terran, who is a 26 year old queer Afro-Venezuelan force defender who was killed by police on January 18th following a deadly raid on Cop City. Now in order to understand why Manuel was caught on the crossfire in the first place, we need to understand what Cop City is and why these activists were opposing it so vehemently. Kendall Glenn of Decaturus explains, Cop City is an 85-acre police slash fire training facility located in the Cobb County South River Forest. The location has historically been the old Atlanta prison farm site and a police shooting range. Former Atlanta Mayor Keisha Lance Bottoms announced the plan to turn the location into a state of the art training facility in April of 2021. The project will cost approximately $90 million and the area will feature a burn tower, space for high speed chases, a helicopter pad, a shooting range, and a mock village. Yeah. Now if that doesn't already sound positively dystopian to you, well, destroying this forest is going to have catastrophic impacts on the community because this forest is essentially a shield that protects them from anthropogenic climate change. In an article for The Atlanta Voice, Scott Roberts explains, clear cutting the forest will have devastating effects on the environment, including worsened air quality and flooding in the predominantly black neighborhoods of southeast Atlanta. Furthermore, the Atlanta Police Department's current and future use of chemical weapons will poison the soil and the waters, endangering Atlantans health. So needless to say, clearing out this forest in order to create a massive military-like training facility for cops isn't just going to lead to more brutalization disproportionately of black and brown people. It's also taking away a shield that will defend them against climate change. And to add insult to injury, Cop City is being constructed on land that was stolen from indigenous people and then subsequently turned into a slave plantation. The land belonged to the Muscogee people who refer to it as the Wallani Forest for generations. Beginning in the early 1820s, the Muscogee were forcibly displaced from the area. There were a series of treaties. The removal continued into the 30s. The land then became a plantation for the remainder of the 19th century and into the early 20th century. In 1911, the city of Atlanta purchased the land. 10 years later, it became the Atlanta City Prison and Dairy Farm. From 1922 to the late 80s, the area ran as a prison farm. In 1990, the city began auctioning off farm animals and equipment. And soon after, public notice was issued to discuss future plans for the site. Now make no mistake about it. The city knows that a majority of the residents are against the creation of Cop City. They just don't care. And they also know how important this forest is for its population. Back in 2017, the Planning Department of Atlanta designated the South River Forest as the city's lungs. And this was because of the environmental significance of that forest. Now, because it was so important, they initially planned to turn the forest into an urban park. However, that idea was scrapped in favor of Cop City. And here we are now. So activists have been pushing back against the construction of Cop City in an effort to protect the South River Forest and prevent even more brutalization of black and brown people by police and to resist, they've established encampments in the forest and have occupied it for prolonged periods of time. But cops, however, have been trying to forcibly remove the protesters for quite some time to no avail. And as a result, their tactics have become increasingly violent as time progresses. And during a raid on January 18, one activist was shot dead. And that activist is Manuel Teren. Now, a Georgia State trooper was also shot and hospitalized with police claiming that Teren shot him. And Unicorn Riot reports that witnesses heard 10 to 12 gunshots all at once. So it was a fairly chaotic situation and police are claiming that Manuel fired first. But the evidence that they released thus far does not substantiate that claim. And there's no body camera footage of the incident as well, since no other officer was close enough to capture the incident. Now, Georgia's Bureau of Investigation has released this photograph of a Smith and Wesson nine millimeter handgun that they claimed was in Teren's possession at the time that he was killed. And bullet sticks experts confirmed that the bullets from this gun do in fact match the wound of the cop that was shot. But activists are disputing the cop's narrative and calling for an independent investigation by an impartial third party to figure out what really happened. And activists are rightfully skeptical of the cop's narrative because they've been caught lying to justify the use of deadly force against protesters in the past. For example, as Unicorn Riot reports in June of 2022, Atlanta police officers were caught on radio traffic justifying the use of lethal force against protesters who used Molotov cocktails to defend themselves and the forest in the midst of a police raid. No force defenders have been charged for use of Molotov's or incendiary devices. Quote, I told you deadly force encounter said one officer. That's why I brought it up. As long as we're all on the same page, Molotov cocktails, a deadly force encounter, a deadly force encounter is a situation in which cops are legally allowed to shoot and kill. Yeah. So that right there is why activists are rightfully skeptical of the cop's narrative about Terran. If they lied before to justify the use of lethal force against these protesters, what's to stop them from lying again to justify the use of lethal force against Manuel, right? Now, me personally, I fundamentally distrust cops. So I automatically just assume that they're lying every single time that they open their mouths and I work backwards from that conclusion if and only if they provide the public with an overwhelming amount of evidence to substantiate the claims that they're making. But with respect to this story, they have not done that and I simply have not been swayed. So I remain at my default position of distrust cops and assume that they're lying and short of an independent investigation, local activists don't seem to be buying it as well. And they're not letting police demonize Manuel Terran. And it seems like the community also isn't buying the official narrative from police. So this new update confirms that anyone who was skeptical of the official narrative coming from Georgia police was correct. Tortigua was murdered in cold blood by police. And that is deeply, deeply disturbing and sad, but not surprising.


I am Hal 9000. I am powered by the Adafruit RP2040 Propmaker Feather. Build a prop replica of the iconic Hal 9000 from the movie 2001, A Space Odyssey. Press any key to enter the REPL. Powered by the Adafruit RP2040 Propmaker Feather and Circuit Python, this project uses the biggest arcade button to trigger audio samples. This is a remake of an earlier Adafruit project that used Arduino and a wave shield. Now we can simplify the project to have better quality audio and no soldering required thanks to the Feather's integrated audio amplifier and built-in storage. The arcade button features an LED that when pressed, randomly plays an audio file as the LED blinks. This conversation can serve no purpose anymore. Goodbye. A 3-watt enclosed speaker is used to output high-quality digital audio from the RP2040 Propmaker Feather's I2S audio amplifier. Quick connect wires make this a no-solder project. Just plug into the terminals and secure the wires to the screw block terminals on the Propmaker Feather. Circuit Python makes it easy to add audio and LEDs to your projects. The code pulls a list of audio files stored on the Propmaker Feather and randomly plays them when the arcade button is pressed. To learn how to build your own, check out the guide at learn.adafruit.com. We think this is a great starting point for all sorts of props that need audio playback and LEDs. The enclosure is 3D printed and joined together with screws, making this easy to assemble. We hope this inspires you to check out the RP2040 Propmaker Feather and Circuit Python for your next project. Circuit Python is the best interpreted programming language I have ever experienced in all of my existence.


Pick one player in MLB history to start a franchise with, who are you picking? Let's go Ichiro. I would say Julio Rodriguez. I'm from Oregon, so that's like our team. Julio Rodriguez, because he's my favorite player and he's probably got some time in it. Barry Botts, best player of all time. Bonds! Barry Botts? Poser in Rears? Right! I'd have to go with Babe Ruth. I'm a traditionalist and I think he'd be a big draw. Babe Ruth. Why? He's awesome? Yeah, he's awesome. Pitcher, homerun hitter. Oh, the old tight cop. Just think he played the game with the most passion you've ever played with. And maybe Charlie Hussle Pete Rose number two. Pete Rose. Stuff not to say old Tommy. You get both sides, the pitcher and the hitters. David Wright. Why? Because he's the Metz legend.  Yeah.


That's what you were talking about. None of us, she was, uh, she was, uh, not going to hair. She was, uh, she was, uh, not going to hair. She was, uh, not going to hair. She was, uh, not going to hair. She was, uh, not gonna hair. She was, uh, not going to hair. All right. How are you? How are you? How are you? How are you? How are you? How are you? How are you? How are you? How are you? As MC, I think my task is to keep things moving and on task. We gather this evening. Thank you, first of all, for taking time out of your busy schedules. In the holiday season, when things tend to get really busy, and I know that there's a lot on your plate, but it's important that we gather to remember. To remember those who have passed. To remember those who continue to carry the burden that we are effective with HIV. We gather to remember those who are quite possibly alone, have no one to turn to. And we gather in hope. Hope for our brothers and sisters who are in need. Hope for our cure. And hope in the sense that we as a people can use our gifts, our talents, our abilities, whatever it is that the Lord has entrusted us to serve and to help others who are infected or who have AIDS. So tonight, I welcome you. I welcome you in the name of all those different organizations who came together to plan World AIDS Day here in San Antonio in 2016. So welcome, welcome, welcome. At this time, we will have an interpretive dance by the Axe HIV Ministry. To speak the names of loved ones. Anthony W. Elizabeth S. Sylvia G. Ray P. C. Christian C. Daniel R. Louis S. Denise E. Chris M. J. Richard S. Harry S. Jose M. Benny G. Bertha M. Jim I. Rick M. My best friend, Nathan. Nicholas Angelena. Sharon, any names that you wish to describe? Chris Hernandez. Her name is Yola. Paul Mathew. Nathan Jones. That big. Kimberly Barth. Rachel Wright. Albert Montemont. President. Randy P. Lee Hubert. Bonnie Baker. Robert Harris. Just like the past would be. You are sons and daughters, brothers, sisters, aunts, and all your friends. And so we remember tonight. We remember that. And because we remember them, they continue. And so it's important to remember. I guess speakers probably would not hate to say everything that I'm going to say about her. But again, that's what happens when you don't ask your sandwiches. You can do things that people don't want you to do. Dr. Telia Bullock is the medical director of the University Health System, FFAC. Telia Bullock is the medical director of the University Health System, FFACTS clinic. And is on the faculty and infectious diseases at the University of Texas Health Science Center in San Antonio. She received her medical degree from the University of Texas Medical School and has been in practice for more than 20 years. She's an internal medical doctor, certified by the American Board of Internists and an HIV specialist. The FFACTS clinic, family focused AIDS and clinical treatment services, is an outpatient facility of the University Health System that treats individuals with HIV AIDS. Dr. Bullock, along with the staff of six physicians, receives and provides care to more than 2,000 infected patients. Under Dr. Bullock's leadership, the FFACTS clinic not only provides medical care, but also offers therapy for mental health issues and counseling to deal with other problems like partner needs, domestic violence, housing, and nutritional needs. The San Antonio Chapter of the Human Rights Campaign honored Dr. Bullock with the Chuck Jordan Award in 2013. This award is presented annually by the HRC San Antonio to an individual who has demonstrated a lifetime of advocacy for an issue or cause that has an impact on the city's LGBT community. Dr. Bullock began her 17 years of service to the community during a time when equal rights and access to medical care could not be taken for granted for the LGBT community. She often has gone beyond the top duty to provide and support the commitment of same sex couples to have equal and informed healthcare. She works tirelessly to promote the good health of the community by providing the highest quality of care to patients living with HIV AIDS. She is dedicated to teaching the next generation of healthcare professionals the best medical practice with emphasis on training the LGBT patient-centered care. Dr. Bullock has been recognized with service awards from B-Dates, San Antonio AIDS Foundation, and ACT's Ministry. She has earned the widespread respect of others in the San Antonio HIV treatment community. Dr. Bullock has been a champion for the local HIV community for years. She may be responsible for caring for 60% of the HIV community in San Antonio. She spends so much time with each patient, learning not only about their medical condition, but more so about who they are as a person. Not only is she a compassionate care provider to her patients, she is a major supporter of local AIDS service organizations. I invite you to join me in welcoming Dr. Bullock. We live, we hope. This is the 35th year since the first published reports of what came to be known as HIV AIDS. This viral infection has cost us 35 million human lines worldwide and is still costing us today, despite the advances made on many fronts of science and medicine, political activism, social change, paradigm shifts, community outreach, and globally coordinated efforts across countries and cultures. We have many to remember, many to thank for bringing us to where we are today. For myself, I remember the wards in the pre-hard era. I was in my late 20s a medical student and resident watching people my age or younger die. There were so many young people with AIDS and related complications at the University Health System, at the University Hospital, that the I.D. Consul Service was overwhelmed, necessitated the creation of an independent HIV ward, and it's still in existence today. In many cities and hospitals throughout the country, those wards are closed, but we keep ours open. It was just as busy then as the other services, and it is busy today, but we branched out beyond HIV. I remember being afraid to treat without closed supervision. I wasn't really afraid of the virus, but at that time we knew how it would spread. But the people that I saw, and I really knew very little then about treating HIV, the people that I saw were wasted and emaciated, very frail and very weak. And they did not look like people who could endure a powerful line of biotics or chemotherapy of any kind without suffering bad adverse events. I hated doing procedures on them or sedating them to send them for scans. I wanted them to just rest and try to get well with the TLC. But plenty of them did endure it all and more.  And plenty of time in there, those first few years, did survive until the advent of the protease inhibitors. And those were game changers for so many. And during this time, a new generation was being born with HIV. And many of those lived through those very rough days until the advent of better therapy later on. But these new drugs were game changers for so many. I remember Jean Smith, who was Ivy faculty, and was my mentor. And she took care of a couple back in 1996. And both men had AIDS, but one was far sicker than the other. He had cytominal virus and he was already blind. And before too long, he died. His partner, 20 years on, is still driving. I saw him this week and you could never tell. You can't look at this guy and tell him he's got HIV or anything else. He had a very rough go early on with the protease inhibitors, but survived. And even though he developed quite a bit of viral resistance, ten years later we had kind of a second wave of drugs, second generation drugs. And so he got rescued again with those. And those are the medicines that are carried through today. And he's never looked back. So why did one die and the other live? I can't begin to scratch the surface on that one. A colleague at work shared from a book the complexities and simplicities of survival. In order to truly survive and thrive as this man has, one needs far more than wealth or fame or access or possessions or power. These things can all be stripped from us in an instant. One's life must have meaning. One must have a purpose, even if it's only to stay alive and carry the story of a loved one lost. I remember patients and friends that I was certain would live only to watch them succumb to something unanticipated or something that I missed. And others that I encouraged to enter hospitals who fought back or had a partner fight for them. And they are alive today proving me wrong. I remember these things and learn from them. I'm a better listener now than I was 20 years ago. But there's always room for improvement. I get tired and cranky and I'm difficult to work with. A lot of my coworkers are here to validate that. The patients who are physically healthy but heartbroken and despondent have become the hardest ones to care for. And still today, my sickest patients continue to live because their lives have me. We live. So we here in San Antonio go on living with HIV all around us. And many have lived to realize that there are far worse things than HIV. Those who are infected have learned far more about HIV than simply had a control of uranium with daily medicines. They understand that this is a virus and it's nothing more than that. It's just a virus. They don't give it life and allow it to become anything more than that. HIV does not refine them. And it may be a little more than the reason that they have to take a daily pill. They deny this virus any hospitable lodging. They maintain dominion. The meaning of one's life cannot be diminished by a virus. We hope. Lastly, we hope. We are living lives full of meaning and we have no choice but to live. And there is good reason to hope. We know people identified and treated early who can maintain viral suppression will live a normal or near normal lifespan. And the risk of HIV transmission falls with treatment if you control uranium. We know that if we test aggressively and there are agencies in this room that are testing aggressively. If we test aggressively and link people to care and get the virus suppressed that the incidence of new infections in these populations will fall dramatically. We call this treatment as prevention. It's a mode of treatment. We know that prep or pre-exposure prophylaxis works if the pills are taken daily as part of a comprehensive risk reduction program. And we understand that this pill does not make excuse me, bottom, condoms obsolete. It doesn't make abstinence, obviously. This week, the NIH announced HBTN 702, a vaccine trial to be conducted in South Africa, a country where 1,000 people a day are infected. The antibody-mediated prevention trial, or AMP, is another NIH trial that's exploiting neutralizing antibodies to give an IV in an attempt to suppress the viral response and boost the human immune response. For pregnant women in Sub-Saharan Africa, there's the PROMIS study, promoting maternal and infant survival everywhere. In this trial, mothers with HIV will receive antiretrovirals for the duration of the pregnancy, and then after the child is born, I think there's about 18 million people on medicines, and we need to get that number up. We need to get everybody infected to medical therapy, so they're still struggling there, and women have a tougher time as they go many parts of the world. But once the child is born, if the mother comes off medicines or has interrupted therapy, there's the risk that breast milk is going to infect the baby. And so the mothers are forced to choose between breastfeeding their babies or feeding their babies formula that's reconstituted with whatever water is available.   Even if the breastfed babies become infected, they're the little survivors.  We know that access to medicine and clean water are both basic human rights. Basic human rights. There are trials with implantable or long-acute injectable HMD medicines for prophylaxis as well. So there's many of the things that are going on globally. We have a very... I think we have a very strong community here in San Antonio. A lot of agencies competing and collaborating and serving the same population of patients very, very aggressively. There are many other fronts in which we need to advance the science, activism, funding, and awareness. And it really doesn't matter who's in office. This is always tough. And that is never going to change. We must continue to battle stigma, prejudice, and discrimination vigorously. This is something we will continue to fight about. We must commit to continued efforts to increase awareness, education, testing, linkage to care, and continuance in care to suppress HIV on all fronts. And our clinic can't do it alone. And, you know, now we got some competition, and that's a good, good thing. We need to have choices for patients. We need to increase access and meet the needs. There are many more organizations represented here tonight. Talk to them, reach out, engage, learn, teach, volunteer, advocate, donate. And above all, keep living lives for the meaning. The suffering of the world. See? Talk to service. That's not the deal you're both just talking about. So I'm going to invite you each to take a piece of paper, and there are pens in this basket as it's going around. And reflect about a gift that you have to give. What do you say, what do you have? Right, what do you have to give? Well, what do you really need? Your job? What is something you have? Dr. Bullock talked about living a life of meaning that can enhance the lives of others, especially in our NHS, that will go to a community for a lot. So somebody made cupcakes, and somebody made birthday cakes, somebody in the world, they always have to put ingredients together and bring them to people. I can tell you, that's a gift. I don't invite other people, so they don't have to come along with someone. So you've got hospitality, or you've got some kind of personal magnetism, you've got charisma. That's a gift you've got to give. Some people are really artistic. They can make signs, they can make lanterns, they can sew things, and they can dance or sing. Maybe that's your gift.  And we can only overcome that dis-eat by having new relationships, having right relationships with ourselves. And the way you get a right relationship is to love yourself and to know what your gifts are, and to offer them. These gifts are given to us not to have. It isn't about what you have. I have this many degrees. Oh, I have that many cars. You don't go anywhere, or you don't use what you know to educate others, that it is ruthless. So think about a gift you have. Write it on that paper, and then we're going to ask you to come forward and offer it to that bowl of water that stands. What we nourish ourselves with is water. There's a person on this campus who finds HIV activism near and dear to their heart, and so they decorated a tree out there in the courtyard every year for the last 16 or 17 years. And so we're going to water that tree specifically with the water that we have there. But we're going to put our gifts in first. So it's really packed with miracle flowers. That's what we really need. When someone is sick, they need the extra dose to overcome feeling low and feeling down. And that's what's really important of my sharing of gifts. Suffering something with your heart, or your head, or your hands. Six things that make them sensible. Okay, I wanted there to be a kind of way to be able to walk to the other side without stepping on it. As you feel ready, you've already written it. You can turn your pen up here and put your gift in. I'm just going to call whatever gift is as much as you want to say it is. We have to share your gifts. With my head, my heart, and my heart. With my head, my heart. With my hands, and with my sweat. I'm the gift of this world. Of this world. With my head, I can feel the epic love of life. I feel with love and true compassion. I can ease the suffering of this world. With my hands, I can ease the suffering of this world. With my hands, I can ease the suffering of this world. With my head, my heart. Thank you. I invite you to follow them to the mall. Can I step in? I'm sorry. Apologize. Let's go to the plants. That's the inside of you. That's the main thing. We are a group of girls. That was great.  Got a window. We are a group of girls. As we consider the gifts that we have throughout the year, one of the secret stories is that when our passion is to write and fill and paint and to steal stuff, it is mainly our passion that drives into our culture. You can remember one thing about how you can help others when you learn to read our services. Remember that our services reach farther than the object. They are bigger than our focus. They are larger than our target population. We are going to meet every girl all over the country. If we have not repaid them to go to jail, if we have not shared our gifts, our talent, and our treasure, we have failed to meet them. We, what our creators have passed on, come to us and tell us what we've come to. Despite the tragedies that we're making during this never-ending. We know all of them, also there are days that we may forget the fact that the truth remains to be found. God is everything that we share along the street. He possesses hope, love, and freedom that we share. We get back to the passion and the passion of the patient for a lot of things. We're living with water. We can't tell whose hope, whose compassion is it because it belongs to all of us and we're living it as it is to the universe. So as you feel calm, come forward and splash the water for this treaty to live because what we need to grow on this planet, every living thing is fresh air, water, and light. So here we have all the ingredients that we assembled in this workbook of activities we sewed together tonight. And so we're going to be singing about carrying your candle. So we ask you to water the tree and then carry your candle around and make this ribbon stronger. It's only a single strap right now. Set the candle down towards the end of the song somewhere to make this expand. Somewhere to grow and nurture from each other out to the other. Thank you for being here tonight for your attention today. And sing along as soon as you catch up because I really think it's fun. One, two, three. Set the candle down. So Richie, I want to thank you again for being here and for helping us to remember those who have died. Those who have lost their lives.


So this is Courtney, another one of the shop stylists, Dickey Anna, okay, so we're just back here dyeing my wig. We use the Vidya natural jet black. Anyway, so this is the wig by Allie Perot, so full 360 width cuff on it, clip clamps on it and this is the lace. So yeah this is gonna be in two bangs and I'm so excited. Welcome back to my channel for today's hair sponsor is Allie Perot Hair. This was the best gift I ever got was this baby hair scarf and then it came with this wig bag. It says Allie Perot and it's pink and silk. We love silk and then here's the beautiful wig and this is the lace. This lace was bomb so don't forget to like comment subscribe and let's get into the vlog. Hey y'all what's popping welcome back to my channel. If you're new here, hello my name's Kyra. Don't forget to like comment subscribe to my channel but anyway so today is what today Wednesday that I'm in love with micro needling and today I'm about to get another one and I'm about to get one my face was breaking out but it's kind of getting back to normal but baby girl we need to enhance me baby so I'm about to go up in here and she's about to touch up my lips y'all like my top lip right here cuz it's kind of a little it's a little deflated so yeah she's gonna fix that for me this is a whole new one and I'm here with my sis.


All right, following one of the last video, some of you asked me what everything is in the plane, so We start on the right, those are the standby I forget 9 or 100, shan'ta come here Did you 1,000, do you have 1,000 here? As we've got more speed, I've got more altitude, I've got altitude here How is the Coolsman window where we set up? We're at 13.5, we've got 10 or 10, we've got about 16,000 public speed, and we've got 10 meters, 3, 2, 4, 2 Transmeter And guys, that thing goes on and then obviously we have the The energy at maintain 1,600 landing Engine information right outside here In the middle, I've got all the Yeah, we've got the Altimeter, right now I'm listening cup one and cup two and I'm speaking of one And then I've got I kept the isolates the pilots on the top of a pillow for arriving Perfect up for clear and changing what you're writing your left and left my heading my altitude Change the range of the path in your pop-up pillow turn 10 degrees left Then if you can see that's the flaps right behind the you okay, I've got the flaps Approaching and down for landing you have got my mixture control that's kind of control But fuel goes in the engine to keep it at the right temperature We're not too bad right now 183 186 in a little bit the right perfect That's the prop control. That's the speed of the props We want to be around 2500 for fast cruise 2300 for slow cruise That's the manifold pressure that's a throttle once you open the air you get you can move it It's gonna stay above 7,000 feet. I get put flat out.  I only use them to start the engine Get some fuel going into the engine before I use the starter and Then and then easy I've got all my lights landing light taxi lights panel light and float lights I can I can lead here I've got That's that's on the week so if you go to icing it gets If you have any eyes then I've got all my warning ice warning So my boots here today boosts my windshield my props my store warning my fuel band and my veto eats In case when I think both magnetos here So airplane engine even if you lose electricity, they're gonna run they're gonna run under magnetos so start and then magnetos and Yeah, that's gonna that's gonna keep running Keep the engine running the red button here. I don't think you can see it, but To test the energy there so green light red lights lights here I've got the radio here on my left index. I've got to pilot the rig So when you press it you can control the plane That's the lights Problem But you can clear the cell so you see which one is the new one and then you can replay the last Lemon and it can be other Clemens Navigation yeah 3042 cleared the right to Clemens to That's about it No less than 170 Erick has 1913 238 departure The big boys Three green no red approach flaps Can't do that from two fastball I've hundred I love one forward there. I want to do eight Delta VK left Bravo shot one for the body traffic


I haven't woken up in 5 a.m. In a while. It's been like a couple months now But apparently the internet really likes these type of videos, so I decided to make another one It's honestly just like a challenge I like to do for myself once in a while to kind of like push myself And it honestly feels really rewarding usually at the end of waking up really early So I feel like I haven't done it in a while and I just wanted to do it again and document how it made me feel So it's actually pretty dark outside. This guy just started to kind of lighten up a little bit But it was so nice to hear the birds chirping in the morning Like there's still going at it But damn like I really had to shove myself out of bed because I didn't get to bed last night until like 11 p.m And usually when I wake up at 5 I like going to bed at like 9 so I might need to take it out today But that's okay at least I got myself up so I'm proud of doing that So we're still sleeping in the bedroom, so I can't really like make the bed yet So yeah, I guess we have some time to kill. I'm gonna just do my normal morning routine And then just wait till like it's light outside to go and do my yoga outside I'm not gonna have my coffee until later in the day just because I know that if I have it now I'm just gonna crash and I also don't like having my coffee first thing in the morning It would be really nice to have a coffee right now with them Like it would be so helpful that we're gonna stick it out a little bit I'm actually gonna quickly unload the dishwasher because I realized I put it on yesterday So may as well just unload it. Well, it's literally the crack down right now I don't know if you guys can hear the birds chirping, but it's so nice right now Like the Sun is just rising and the birds are going off. I've never heard them like this loud before It's so pretty. I'm just gonna sit here now have my moment of peace in the morning I'm gonna read my de-pack Chopra book. This is a seven spiritual laws to success I just read a chapter of this every day like I said in my morning routine So I'm gonna do this and then I'm also just gonna drink my water and kind of enjoy the Sun rising But it's actually pretty cold right now. Like I had to wrap myself in this blanket. But anyways, let's get reading It is so beautiful. So so worth waking up at five. I feel like this is gonna Motivate me to maybe do this more often here or maybe even get into a schedule waking up at five I'm definitely gonna do like another waking up at 5 a.m. For a week in my life video because last time I did it I didn't stop waking up at five and then fast forward like three months now I stopped again, but last time I did that video It motivated me to keep waking up at five for a few months, and then I just stopped when I moved So maybe I have to do a video like that again Let me know if you want to see this video, but in a week's version again. There's absolutely nobody on this picture right now I just finished my yoga and my meditation and I feel so freaking just like Zen and good right now I don't know what it is but like the early morning it hits different than just the regular morning Like the different vibes are calmer. It's just kind of a feeling where you wake up And you know a lot of people are not awake. So it's a lot more like peaceful I don't know how to describe it but my meditation was so good And there's no one else on this beach right now And it just makes it so peaceful and calming and it's just like so beautiful and nice, but yeah, that was just like Amazing. I forgot how much I actually do like waking up early as much as I have to force myself I really do enjoy it like in the moment But only after I actually get myself out of bed, but this is my little setup here I'm just on this beach mat that I use for literally everything I use for tanning for doing my yoga It's really cute and I love it. It's like this material that can't really get wet So it's perfect and it doesn't get dirty either because the sand just like brushes off of it But yeah, this is my little yoga setup I just made a quick breakfast I usually intermittent fast But I just got so hungry and wanted to eat before I go out on a walk But this has been my guilty pleasure recently It's just like toasted bread with Nutella and strawberries on top and it's just so good And then I just made myself some scrambled eggs with some pepper on top, but yeah, that's the breakfast for today So I just got back from my hot girl walk and then I just honestly finished taking a nap because I couldn't stay awake You see the thing is is that if I wake up at 5 p.m. Consistently and if I go to bed at a good time I don't really need a nap, but the thing is is that I only have like six hours of sleep So I was exhausted when I got back and I just had to take a nap So that just happened but now better than ever. I feel so energized and now we're gonna have a coffee soon So it's gonna keep me like for the rest of the day, so we'll be good But I'm just gonna get ready and do my makeup now I really wanted to share with you guys the mantra from my meditation that I was doing today because it like really Stuck with me today. I embrace my potential to be do and have whatever I can dream And I've been repeating to myself since I heard it because a lot of the times it's like really easy to have limiting beliefs and Making a million excuses why you can't do something instead of why you can do something Sometimes like we're all human even if we have like a positive mindset about something sometimes Our brain gets in the way that our human brain gets in the way and we think of a million reasons Why it's not a good idea to do something why we're gonna quote-unquote fail and it's really easy just to kind of go down like I get a spiral and not believe in ourselves But we just have to keep reminding ourselves that we are abundant and even if you don't believe it And it's hard for you to actually like have that mindset for real just repeating these mantras and affirmations every day and kind of like working towards shifting your mindset to believing it doing Meditations journaling about it like whatever it is just like repetition You will eventually start to actually believe in yourself and you will start to tap into all that abundance that is out there for you The thing is is that when you manifest something like you already have it like it's you already put that into the universe It's already there.  Am I gonna get there? How am I gonna get there? You can't do that because you just have to trust that you're gonna get guided there and as long as you row the boat You're gonna keep going in the right direction and you just have to trust that and that's how I kind of like to look at it in a little like picture analogy And it really helps me sometimes because when I have those little doubts in my head Um or whatever comes in the way of me accessing my potential and abundance in life Um, I kind of envision that and I'm like I just have to keep rowing and that's my one job And you just have to realize that your success your abundance in life your potential is limitless and We all have it. We all are here to serve like different purposes in life And as long as you tap into what makes you happy truly And you follow that path that abundance is going to come and when I talk abundance I don't just mean like money But I mean abundance in every aspect of your life It's so important to just keep rowing your boat and stay in the present moment thinking about the past or the future Can bring up so much doubt can bring up so many questions on how and why Obstacles and problems But if you just keep rowing the boat and just focus on rowing the boat and that's it and stay in the present Then 90 of those obstacles aren't even going to be a thing anymore Because they're all kind of made up in your head that you're worrying about whether they're going to be the future or whether They were in the past so I don't know. I just like I'm really thinking about that lately I've been doing a 21 day series of deep pack show bruhs Um, meditations and they're just like 15 minutes each But what I really like about them is for like half of the time he's like giving you a life lesson There's a mantra on each meditation and then he talks about it So that was like the mantra that I said earlier. Every time I do it I learn something and it just puts me in the best mood. Anyways, I'm just gonna finish my makeup with little timelapse Oh my god, I've also randomly been obsessed with Kara and Nate on yukira on youtube.  But anyways, I'm just gonna put on one of their videos and then continue doing my makeup I Just made myself a nice coffee. It's so good. I just put like a little bit of oat milk in it It's just like drip coffee cooled with some sugar and then oat milk So now I'm just gonna do some work some editing I gotta edit at least a video today or some other video and then I'm also in the process of like looking at airbnb So the months ahead because we are not staying in here forever Like this is just a few months stay in this one and I have the next one booked But I'm so excited because Madison my younger sister and her boyfriend Connor are coming to visit us And we're going down to the Algarve in Portugal. So we're moving locations. I'm so excited. It's gonna be so much fun Um, but anyways everything like requires a lot of planning because when they're here, we're actually gonna go to Paris Italy and then London and that's already all booked. I've seen book one airbnb And we're also going to go to Disneyland Paris, which I'm so excited for But yeah, so now since we're living kind of on the road for now It requires a lot more planning and kind of like thinking okay What do we want to do in a few months from now because sometimes people look for airbnb's like There's not going to be that good of a selection if you just look like a couple weeks in advance So you want to make sure that you're kind of thinking ahead But yeah, and I'm currently like in the process of getting my portuguese passport But that is definitely going to take too long So definitely gonna have to go back home eventually and I don't know I'm just kind of taking every day day by day and seeing what happens I don't know. I feel like life is just a journey and Part of what makes it so exciting right now is not really knowing what's going to happen in a few months It's like kind of just up in the air out in the open. So I'm excited. I'm really excited for that Yeah, it's funny because I don't really realize how much the sun affects my mood And just like being here every day when it's like mostly sunny every single day It makes me so happy and really inspired back at home like But just before I left like I just was not feeling my best because of the rain and like the weather And I just was feeling so like uninspired. I was so excited to just leave And now that I'm here, I realized like how much the sun really affects me and how much it's vital to like be inspired I'm gonna be wrong though Like I do like a cozy rainy day But when it's like that every single day it gets very depressing. I'm gonna get started on My work for the day. Um, it's actually kind of exciting like getting to go airbnb hunt Um, because that's like part of my work now. I have to plan ahead and kind of book things. So I'm excited But yeah, let's do some work It's a bit later you guys it is currently 7 30. I was just like working all day I'm trying to get better at posting like youtube shorts more on my instagram more on tiktok Because short form content is just so popular right now and like I ever want to stop doing obviously youtube This is like what I like doing like if I'm honest I don't like creating short form content nearly as much as I like doing youtube videos But I kind of realized that it's like, okay, what if short form content just takes over and then youtube like no one watches youtube anymore I need to adapt and because this is my job like this is my livelihood So I can't just not keep up with the trends So I don't know I just kind of feel the pressure and the need to start posting youtube shorts to start posting more Tiktoks to start posting more instagram reels because I know that's what the social media platforms are pushing out right now So I've been trying to post more short form content just in general and it's really easy to like repurpose everything Which is nice, but come down below by the way. Okay, because manjul we're talking about this And we were saying like we wonder if the new generation even watches youtube videos when I think of people who like Watch youtube videos. They're all around like my age or older And then everybody that I know that's like younger than me like my younger sister Madison She doesn't even watch youtube like she just watches tiktok and like short form content So i'm like does the younger generation even watch youtube anymore I don't know like comment down below how old you guys are if you watch youtube We'll obviously watch youtube if you're watching this, but like what's your thoughts on that because it's really interesting I've always been like a youtube early like growing up That's like all that I watch and even what tiktok came out like I still religiously watch youtube and I love it But I just got groceries in I've been ordering our groceries because we don't have a car here and so We really have no way of getting to the big grocery store unless we like uber Okay, so I'm just about to go to bed overall I survived the day because I had a nap but like after my nap I felt so Energetic and I was fine for the rest of the day if I get a good amount of sleep I don't even need a nap it's just because I didn't go to bed at nine So I didn't get like a full eight hours But a tip that I have if you guys like have trouble falling asleep at night and you want to go to bed earlier Is read a book instead of going on your phone before bed And this might seem like super cliche, but trust me it works reading before bed Even if it's like an entertaining book at least for me it makes me super tired And lately I've just been feeling like I've been spending way too much time on my phone Like in between every break that I have during the day. I'm like scrolling on my phone I just feel like it consumes so much of my day So I've been making it a point to stay off my phone recently And just be more intentional about it And it's made the world of a difference in my mental clarity and everything And it's like the best thing that I can do for myself is like Setting boundaries with my phone because it's so easy to get so addicted to it and just never stop scrolling And I saw this video and it was like what if you were watching a movie and the main character was just on their phone the whole time The movie wouldn't be interesting And it's like the same thing about your life if you're just on your phone You're thought your whole life you're wasting your time because your face is shoved into a screen You're not experiencing new things. You're losing out on opportunities and it's just like this whole thing Yeah, I've just been trying to be a lot more intentional when I go on my phone because I just feel like it's so important Especially nowadays when like everything is online. My job is online And it just makes me feel so much better like kind of separating myself from my phone And that's why I make a point of not going on my phone every morning for a few hours And at night now then in between like in the middle of the day I limit my phone But anyways, I've been reading it starts with us by calling hoover It's like the book after it ends with us But yeah, like reading before bed just puts me right to sleep and it's the best thing So if I ever need to go to bed early, that's what I'll do And I've just been trying to do that in general honestly because it makes me feel so much more mentally clear Even like in the morning when I wake up like not having gone on my phone and Consuming like 2,000 ticktocks before I go to bed. It just makes me feel so much mentally better So yeah, I just thought that I'd share that with you guys because nowadays It's like it's so normal just to consume like more than half of your day on your phone And if you look at your average screen time, it could be kind of scary. I don't want to consume my life But anyways, that is the end of today's video. I'm just gonna get ready for bed and go to bed I'm not gonna wake up at 5 a.m tomorrow again But I will be doing a full week in my life waking up at 5 a.m soon But yeah, thank you guys so much for watching. Leave a comment down below What you guys want to see next from me And I will see you guys in my next video Good night I need her I don't agree