One of WordPress 6.2's most exciting new features is called the Style Book. This Style Book creates a visual representation of all the styles that will automatically be applied across your website, saving you time and letting you design and actually see the changes you make all from one dashboard. From colors to fonts to button sizes, this preview gives you a strong idea from the start of a website about what your new block theme will look like. At the end of this tutorial, you will be able to use the WordPress Style Book to customize your block theme. Let's find out how! Imagine you are creating a new website using the block theme 2023. To find its Style Book, from your dashboard, hover your mouse over the Appearance Navigation link in the left-hand sidebar and select Editor. Then, click on the site editor to the right. Click the Styles icon in the top right-hand corner. Then, select the Eye icon that appears. This is your block theme's personal Style Book. From here, you can see how the stylistic changes you make will affect the appearance of your website. Depending on your block theme's options, you can make sweeping changes to your fonts, change your background color, and, in some themes, change your layout options. This WordPress Style Book provides five tabs, text, media, design, widgets, and theme so that you can quickly see the changes you make take effect, all without having any content on your site yet. Any future content I write or any existing content on my website that uses these styles will have this style applied to it. The Style Book also allows me to add individual styles onto specific blocks. For example, say I am a writer and will often use the quote block on this website. I would like to customize just this one block because I would always like my quotes to use a certain font and stand out from the rest of the text. I navigate to the quote block by clicking it on my screen. This takes me to the quote block. From here, I can make changes to the font that only affect this quote block. I select a font that I'd like to use for my future or existing quotes, and I make it a little larger so that it will stand out. Finally, I make it italic. Now, my quote block will always stand out the way that I've just styled it, even if I make sweeping changes to the rest of the text on my website. Here's a pro tip. To avoid a theme design headache in the future, I recommend that you stylize individual blocks sparingly. It's important to note that if you make individual changes block by block, changes that you intend to make globally to the rest of your website will not affect this particular block. Notice how I changed the font globally under general styles text. Did you notice that the quote block I just styled did not change? Let's say you find and install a cool new font that you'd like to use everywhere on your website. If you styled every single text block individually, when you make what you hope will be a big change site-wide to all the text, your individually styled text blocks will not change. You'll need to style them again. To reset a single block style back to the defaults, I can head back to the block's individual style settings either by clicking on it again or by navigating to it in the styles panel on the right by clicking blocks, then searching for quote. If I reset this block to the default font, that tells WordPress to use the font that I set in the site-wide global styles you see when you first enter this global styles icon. Now, that will allow me to style my website's fonts, quotes and all, in one place. The changes I will make globally to my text site-wide, rather than just in this individual quote block, mean that if I change my font, it will now also apply to this individual block. With thoughtful design, I can get started working on my new website from scratch, or I can give my existing content a brand new look with a few clicks of a button. The style book also allows me to double-check my website for accessibility. For example, I noticed that the calendar widget on this theme is not accessible with the color scheme that I picked. The contrast is not high enough. So, for this specific instance, I customize this block to my liking, and now anyone who requires a strong color contrast will be able to read this calendar. Now, you know how to use the WordPress style book with your block theme. To learn more about the features coming out in WordPress 6.2, please visit learn.wordpress.org for more tutorials, online workshops and courses. See you next time.


What's up men? I've got some thoughts for you younger guys today about these recent messages that have come out from the American Psychological Association about masculinity. And if you're not familiar with what I'm talking about there's two pieces to this story. There was number one a set of clinical guidelines that the APA put out for clinicians to use in working with men and boys. And then there was an introductory story that came out in their magazine just talking about these guidelines. And while they stopped short of calling masculinity a mental disorder, they didn't stop short by much. The message is very clear that if you possess any kind of traditionally masculine traits that you're a danger to yourself and others. And in the introductory article there was this line that has gotten a lot of play that I think sums up pretty nicely where the APA is coming from. Traditional masculinity marked by stoicism, competitiveness, dominance and aggression is on the whole harmful. Now on both the guidelines and the introductory article they refer to these things as traits. And that's kind of sloppy language but it's fair. You can think of traits as clusters of behavior that help you move through the world. And it's fair to say that these traits are more commonly expressed in men than women that there are other traits that are more commonly expressed in women than in men. So all that's fine. But to say that traits on the whole are harmful is just about the stupidest thing I've heard all year. But it's only January so the APA still has time to outdo itself. Let's look at a trait for example like compassion. I'm sure the APA would say that something like compassion is a good trait to have but it's good to have if it's done correctly. If you do compassion incorrectly you put yourself at risk for being taken advantage of and you also risk weakening other people by creating resentment and entitlement in them. It's a very common problem. And so compassion may be a wonderful trait to possess but it has to be done correctly. You can apply that same analysis to all four of these traits that the APA has called harmful. So start with stoicism.  And this is something that anyone who's over the age of two should be striving to develop and refine. Now if you've been in the workforce for any period of time you've probably worked with the guy who bitches and complains about every little thing but doesn't bring a lot of solutions to the table. That's a guy who hasn't mastered stoicism yet. He hasn't learned how to contain his emotions and turn it into actions. And he's a detriment to himself and he's a detriment to the team. On the other extreme is the guy who has a problem that he should bring to the team but he won't do it because he's proud or he thinks he's going to be in trouble or whatever his reason. And I know because I used to be that guy. He's a detriment to the team for a different reason because he's not bringing an alertness to the team that he should be bringing. And the same thing can apply to marriages and just interpersonal relationships. There's a line that a man has to find between suppressing his emotions and expressing real problems that need to be solved. So look at the next one, competitiveness. This is nothing more than the drive to outperform somebody else or outperform yourself. This is not on the whole harmful.  None of these things would exist without people competing with each other. It's the ability to look at yourself and try to outperform the next person and come up with a better idea, better mousetrap, a better way of doing things. That's what's created this wonderful society that we live in.  Now a person could be too competitive to the point where they're ruining their relationships and they're not succeeding because nobody wants to deal with them or a person could be not competitive at all to the point where they're just relegated to a minimum wage job for the rest of their life. But competitiveness done correctly is a huge asset to any man. Dominance is the next one they say is on the whole harmful. Guess what? We live in a hierarchical species, meaning that if you're not going to vie for dominance, then somebody else is going to be dominant over you. And sometimes you make those choices that you don't want to be the one in charge, but you can only make those decisions if you develop and you refine your sense of dominance. Dominance done incorrectly is abusive and nobody wants to be around that person or it's just absolutely submissive. And again, this is a hard person to deal with. Dominance done correctly is called leadership. And if you go to a bookstore, you're going to find shelves of books on leadership, which might as well have dominance in the title because that's really the theme is how to be dominant in a way that serves yourself and serves other people. And finally, let's look at aggression. Aggression is, again, not a destructive or harmful trait. It's just drive. It's the drive to solve a problem is to drive to defend somebody. It's the drive to create a better condition for yourself or somebody else. Aggression by itself is not a harmful thing. I argue that the absence of aggression is actually far more harmful because without aggression, you don't have the energy that you need to solve problems. The APA clearly wants you men to relinquish these traits. And why do they want you to do that? Well, I don't think it's to help you. I don't think they're acting in your interest. I think it's to help them. And the reason I think that is that when I read the guidelines, I come across sentences like this one. When working with boys and men, psychologists can address issues of privilege and power related to sexism in a developmentally appropriate way to help them obtain the knowledge, attitudes and skills to be effective allies and potentially live less restrictive lives.  I don't know what that means. That's gibberish to me, but I know what that first part means. It means that they want you to become their allies in the war of ideas and they want me to manipulate you into doing it. In a couple of sentences later, they even talk about the fact that if I can persuade you to give up your masculinity, you're more likely to go out and participate in social justice activities. I think this is all about getting you to participate in their agenda. And I find that to be absolutely repugnant behavior on behalf of the APA. That's just my opinion and my interpretation. Maybe you disagree and that's fine, but there will be things in your life that are worth fighting for and you won't be able to advocate effectively if you don't spend your entire lives developing and cultivating and refining these very traits that the APA is trying to shame you into relinquishing. So how do you cultivate these traits? Well, it's a lifetime of trial and error and successes and bloody noses and most importantly, surrounding yourself with other men who are trying to be the best versions of themselves that they can be.  Just know that that's worth ignoring.  They're doing it for their own competitive reasons. Don't let them take the keys to your success. Go out there, be toxic, be the best versions of yourselves you can be. I'll talk to you soon.


Now I'm going to go back to the dashboard and here I'm going to demo for you the dashboard default layout. So here I'm at my immunization dashboard. Let's say I want to edit this dashboard. I want to change the layout. So I'll go to the edit option. And now in the edit menu, you see quite a lot of changes from what you had, we had previously had in prior versions of THIs2. And the big one is here, now we have this layout section. And in the layout section, I can change the layout, and I can change the layout from free flow, which is what we've always had, or fixed column. And if I do change the fixed column, I can specify the number of columns. So right now it defaults to three, but I can say I want to go up to say four columns. And if I click save layout, then you see that my dashboard has automatically changed to having four columns. Then the other option here I have is add new items. And I can add the new items either to the end of the dashboard, which has again always been the option. Or I can do start from the beginning of the dashboard at the top of the dashboard. So let's choose this. And let's just add a few items. I'm going to choose the chart I just made, as well as a couple of others that I've made before the session. So I'm going to insert this one. I'm going to do ANC3, ANC2, ANC1. And there you go. So as I was adding those charts, you see that they came to the top. And you see that I've actually have three different charts here that have a legend applied ANC1 coverage, ANC2 coverage, ANC3 coverage. And then just for the sake of an example, I have another indicator that's per 10,000. So this is in patient cases per 10,000 population. All right. So now I can just save these changes. And here you go. Now we have a new dashboard layout. And hopefully you appreciate how easy it was to reorganize the dashboard by columns and then add my dashboard items either at the top or at the bottom.


This is stock number 20223a. We are here at Summit Automotive in Fond du Lac, Wisconsin near new and use light-duty truck headquarters. Today, we are checking out this super clean 2018 Ford F-150 SuperCrew five and a half foot short box XLT Sport. This vehicle has the 3.5 liter V6 twin turbocharged EcoBoost motor which pumps out 375 horsepower This truck has been fully Safety to and inspected by our service shop has a fresh oil and filter change. All the fluids have been checked and topped off for brand new tires and this truck is 100% ready to go Magma red is the color we shoot all of our videos in 1080p 60 frames per second So if you have HD capabilities on your computer tablet or a smartphone device Turn them on right now because it is definitely your best way to check out the quality and condition of the truck before seeing it in person And if you'd like to check out all the photos on this truck in the upper right hand part of your screen There's a link right to our website. Click that and check us out there. This one comes with the painted and polished aluminum rims 275 65 r 18 Goodyear Wrangler 4 to 2 tires on here. They are brand new All the way around. We put those on in our safety inspection and brand new tires on here Magma red metallic is a really good looking color. I believe it came out in 2018 It's a really dark red almost like a root beer brown front bumper Is in excellent shape. No denser dings on that factory fog lights The hood is in really nice condition as well. I didn't see any dense or dings on there Headlight lenses are nice and clear And that front fender is in excellent condition as well Pass near side rim. No scuffs or scrapes on that and that tire is brand new too As you go down this side of the truck take note of how clean the body is how reflective and mirror light that paint is We take these hd videos So if you are far away or even if you're close by and you just cannot make the trip down But you're still interested in purchasing the vehicle You can see the truck hear the truck And have confidence in the vehicle that you're looking at Before you even get here so that when you do get here, there's absolutely no surprises And that is why we offer the summit auto fast pass option in the upper right hand part of your screen A link right to our website where you can apply for financing Get pre-approved see a payment quote even appraise the trade off from the company your own home So when you get here, all you got to do is drive the truck. Love it. You'll be all set to go Back rims in nice shape as well and that back tire is brand new too Framing underbody on this truck Pretty nice shape There's all the remaining factory exhaust Lower rockers all look really good And it does have the nice factory painted step bars You do get your chrome tipped exhaust As we come around to the back of the vehicle rear bumpers in really nice shape Didn't see any denser things on that Backup parking sensors locking tailgate Does have the backup camera Has a drop-in factory bed liner and then it does have the led Bed lighting so they got the button back there. You can turn that on turns the cargo lamps on as well as both led lights In the back here, and then you just press the button and then go off Tailgate shuts nice and solidly and as you go down this side of the truck just as clean as that passenger side No denser dings on the box here. It does have the capitalist fuel fill which you've never tried that it's a pretty nice thing to have And the back room is in excellent shape as well Down the rest is side of the truck looks really good doors are Very clean. It does have the driver's side door code entry, which we have the code for heated mirrors built in directional single signals blind spot mirrors Inside the xlt sport package gives you the black cloth interior There are no rips. There are no tears on the seats. They are in Really nice shape Power driver seat both these front seats are heated. We have factory floor mats throughout Power pedals auto headlamps tilt and telescopic steering wheel Power windows power locks power mirrors you get the cool carbon fiber door trim there We'll hop inside the truck and check out The miles and everything it's built for tough animation there And you can see that this one has 35,341 miles instrument cluster is very nice and clean leather wrapped steering wheel cruise controls and information center controls on the left volume and bluetooth controls on the right no scuffs or scrapes on that steering wheel very nice condition This one does have the turn dial four-wheel drive the pro trailer backup assist Factory brake controller has the sync eight inch radio Am fm and serious xm radio capabilities. It also has the factory navigation This is where your backup camera is going to show up if you hit the plus button It'll go right over your receiver hitch So that's pretty cool and then um You also have your am fm and serious xm radio capabilities on here And then you also have Your mobile apps and apple carplay and android auto capability so you can project your cell phone to the screen So if you had a navigation system that you liked better than the factory navigation system You could project it to the screen same thing with music and media and stuff like that Down here you have your cd player your climate controls including your heated seat buttons This one does have the 10 speed automatic transmission. I know that because if I put it In drive it'll tell me how many gears I have on the right hand side there. So that is the 10 speed You also get 110 volt 400 watt plug-in and a 12 volt power point And then the passenger side floor mat and seat are in excellent shape. I really like that tire tread pattern In the seat there. It's really cool. The headliner is in really nice shape as well And you do get map lights up there in sunglass holder We'll take a quick look at the back seats and then we'll check out under the hood Back seats are in nice shape as well.  Of course all the doors are going to look really good since they're all aluminum here We'll start it up and take a quick look under the hood I would personally like to thank you for checking out the video today and hopefully from this hd video You will have been able to tell just how clean this truck is all the way around inside now Under the hood we have the 3.5 liter twin turbo v6 Eco boost engine and jamae's very clean runs very smooth This truck has been fully safety and inspected by our service shop As a fresh oil and filter change all the fluids have been checked and topped off And this truck is 100 Ready to go for brand new tires I would highly recommend it from a quality condition And look standpoint and to see more pictures of this truck or one of our other 450 new and used cars trucks scvs minivans wranglers half tons three quarter tons one tons you name it We got it go to our website www.summitauto.com Full pictures and descriptions of every single vehicle from two locations all at summit auto.com And if you like to check out more hd videos you can go to youtube.com slash summit auto Remember to like subscribe and share on this video and all the videos that you see there In fact in a second you will see a link to subscribe to our youtube channel on your lefty link to more F-150 videos like this one on your right If you have not been to a website on the bottom link to this vehicle on our website click those check us out And we're super excited to be helping with this 2018 forward f-150 super cruise short xlt sport and magma red metallic. Thanks again for checking out the video


Why does our hair turn gray? And are there any current solutions for gray hair? Well, Lifespan.io has recently interviewed University of Alabama Birmingham professor Melissa Harris on the problem of graying hair and possible solutions to it. We'll have this story and more in this episode of Lifespan News. Welcome to Lifespan News on X10, your source for longevity science updates. I'm your host, Brent Nally. If you missed our last episode, then you can watch it by clicking the card above. We encourage you to check the description below for links to these stories. Continuing with our first story, in her interview, Professor Harris explained that graying hair is thought to follow from the loss of specific stem cells called melanocytes, which are responsible for the production of hair and skin pigment. A reason why scientists have taken on this problem is that hair grain is an accessible easy to check marker of stem cell dysfunction. Making it easier to see if therapies are having an impact. Unfortunately, though, at the current time, there doesn't seem to be any treatment available to repigment hair, although different studies have observed hair repigmentation as an unexpected side effect of unrelated treatments, inducing researchers to suspect that hair discoloration may be reversible. In the interview, Dr. Harris also explained how research into melanocyte dysfunction may improve our understanding of stem cell dysfunction in general. Dr. Harris also said results of recent mouse studies on hair loss and repigmentation are promising and with some luck, we might see commercial applications in humans soon. For our next story, rapamycin is not a caloric restriction mimetic. Rapamycin and caloric restriction are two of the most reliable lifespan increasing interventions. Over the past two decades, a hypothesis has emerged that rapamycin is effectively a substitute for caloric restriction. Now, a team of researchers in the Netherlands used progeroid mice to investigate whether rapamycin really is a caloric restriction mimetic. Young progeroid mice fed rapamycin had no increase in lifespan. The researchers repeated the experiment in older mice and still found no increase. Likewise, varying the rapamycin dosage didn't lead to longer or shorter lifespan in these mice. The researchers also evaluated the health of the liver, vascular system, and nervous system in these mice and found no improvement. Basically, although caloric restriction clearly increases their lifespan, rapamycin seems to have no effect. So it seems like rapamycin and caloric restriction affect lifespan via different mechanisms. So this is bad news in terms of having a substitute for caloric restriction, but good news in that we now have two different reliable interventions which we can compare and investigate. By the way, lifespan news is released every Tuesday at noon Eastern time while our other X-10 science and advocacy videos are released every other Thursday at noon Eastern time. Our next video on X-10 will be Thursday, February 4th, 2021 and the topic is DNA methylation. We encourage you to subscribe to our new X-10 YouTube channel. Once you're subscribed, be sure to click the notification bell and select all notifications to ensure you don't miss any videos. Now, back to the news. A study in rats suggests that glucosamine could be a caloric restriction mimetic. Glucosamine is a polysaccharide that naturally occurs in cartilaginous joint tissues and is involved in protein and lipid synthesis. Glucosamine is also present in other tissues such as skin, nails, bones, and ligaments. Sunovial fluid contains glucosamine and occupies the space between joints, helping to reduce the friction of joint surfaces. Glucosamine is commonly taken as a supplement to help with the joint pain and inflammation associated with aging. Glucosamers gave regular doses of glucosamine to rats and then tracked various biomarkers. The treatment led to an increase in reactive oxygen species for ROS in both young and accelerated aging rats. The treatment also led to an increase in various antioxidants. ROS are reactive molecules and free radicals derived from oxygen and while ROS do have some beneficial uses such as being used by immune cells as a component of the killing response to combat microbial invasion, ROS are also very harmful to cells. Free radicals each possess an unpaired electron making them highly reactive and thus able to damage all macromolecules including lipids, proteins, and nucleic acids. The researchers believe that treatment causes a transient increase in ROS which then leads to a protective response, a process known as mitahormesis. So keep in mind that these results are of course in rats. But the idea that similar effects may occur in humans taking glucosamine is not beyond the realm of possibility. For our next story, synelytics alleviate age-related cognitive decline. A new study by a team of researchers including Dr. James Kirkland of Mayo Clinic tested the effects of whole body senescent cell pruning in mice. In this study, the researchers used mice engineered so that their senescent cells would be destroyed upon exposure to a specific trigger drug. The scientists examined the brains of young and old mice and observed an age-dependent increase in senescent cells. The researchers then went on to administer either the trigger drug or the cancer drug disatinib and the dietary supplement coercitin, which is a known synelitic combination called D plus Q. The researchers observed that both treatments reduced the number of senescent cells in a specific brain cell population, as well as the secretion of SASP, a pro-inflammatory chemical secreted by senescent cells. Additionally, both treatments appeared to improve the cognitive abilities of the mice. These findings suggest that an effective senolytic treatment could improve brain health and reduce age-related cognitive decline. So while this research was of course in mice, there are multiple senolytic drugs poised to enter human trials in 2021. For our final story, scientists published a blueprint to apply artificial intelligence to extend human longevity. A recent comment paper by Dr. Alex Zhavorankov of Deep Longevity argues that it's time for AI tools such as deep aging clocks or DAC to become part of physician's toolkits. The paper also argues that the employment of AI technology to the field of longevity medicine will facilitate the discovery of new, personalized drugs and drug targets tailored to specific individuals. Zhavorankov advocates for the cooperation of clinicians, geroscientists and AI researchers to gradually bring AI-based experimental longevity medicine to the clinic. So as with all our stories, if you want to learn more, make sure you check the description below for links to these stories. That's all the news for this video. Before you go, there's a few quick, free and simple things that you can do to help us solve the human aging problem. If you haven't already, please make sure you like this video. Share this video on your social media. Make sure that you're subscribed with the bell turned to all notifications to ensure you don't miss any videos. Is there a recent life extension story that you think we should have included in one of our recent videos but haven't yet? And which of the stories from this video excited you the most? Let us know what you think in the comments below. We really appreciate it and we look forward to seeing you in the next video, at least as healthy as you are now.


I love sociology, so getting to share sociology and how we can connect individual problems to structural issues is something that I really enjoy sharing with other people. I enjoy most working with students when they're trying to figure things out. I'm always trying to engage how our students interacting with things, how can they incorporate this into what they know, and how can I make it better so that they can, you know, do better with it. And so I teach really big classrooms of like 500 people at one time and then I teach really small classes in Cornerstone with 30 students at a time. It's really interesting to just sit down with students either on that big level and ask a big lecture-wide question and have students, like their light bulbs go off and they figure out, oh this was the theory that works best here, or when you're sitting with students in a small group discussion you're talking about like how does this article help us better understand. I chose to teach here because of how rich the teaching environment is. Being able to come to Purdue and having all of these technological resources and all of these people who were excited about innovating was something that I was really excited about jumping on board with. People have been so encouraging me the entire time I've been here. Everybody's been supportive and asked me to come on to projects and that's been fantastic. And then winning this university-wide award is very validating that I have been trying, like I've just come here and I was like I wouldn't take advantage of everything I possibly can and then getting recognized for that is pretty, it's pretty awesome. So it's a nice thing to be able to think about every once in a while. Everybody is always so supportive of my ideas and of helping me get to where I want to go so I can't imagine a place that would help me explore teaching more than Purdue is. I think that people at Purdue really genuinely care about undergrads. Everyone I talk to cares that undergraduates are getting the best experience possible and we want for them to have these good learning outcomes and for you to meet them and everybody that I talked to was always working on making their classes better to better engage their undergraduates and to push them farther. The students here are so much fun and they're so engaged with learning. They want to be here and they want to learn how to make the world a better place or how to do better in their careers and I really appreciate that about our students.


We get a couple of minutes Okay Okay, well, I think you guys did an awesome job Yeah, thanks. So, you know as an interventionally trained physician That's now just practicing Cardiology in the community one of the things that I hear is the age So we were talking about 65 year old not 85. There's a big difference, but 65 years old in Arizona is middle-aged. We're treating people with structural heart We're offering them valves. We have a lot of treatment options up until in their 90s really and if of course Frailty has to come in because we're not going to offer people that are bedbound. We want to see a quality of life So definitely we're going to look at the constellation and the and the quality of life But when you're talking about the cost in the United States of medical care, this is going to be Future this is what we're finding genetics AI making these diagnoses are going to be what's in front of us And so although the costs are astronomical now because of this one drug as we get more competition and Hopefully look Amazon is now providing insulin for $35. We may have companies that say, you know What we're going to go ahead and we're going to help these patients with these orphan diagnoses So I think that as we expand and go into the genes and the genetics we should be looking at all of these disease processes We never withhold dialysis. We give patients until they want it We ask them what they want as long as we're honest and give them all the risks and benefits of where we see them I don't think there's a problem making the diagnosis I agree that then the offering and seeing what we can do But that's where I think as a society we need to put pressure on the drug companies because we all know that's where the problems are It's they're trying to make money and they're doing it at the expense of lives of our families and our patients So I Completely agree with you. Dr. Agarwal, you know, I do a lot of geriatrics actually spend most of my career doing a lot of geriatrics You know, there's no way I can tell you that I have a 82-year-old guy from Sun City that comes to my office Which is in the West Valley a doctor. How are you doing? I'm playing three rounds of golf a week And you know when it comes to to like that patient, I would offer him Everything that I have I would treat that patient based on his functional status not on his, you know H H is just a number for that particular patient. I am not going to offer You know this life saving therapies of 225k a year to somebody that is in the nursing home That I know that has a life expectancy of six months to live on palliative care That's what we were pretty clear to make the point that we would just Carefully select and and this individuals that we are just considering, you know screening for the disease Which actually I think at the screening level is actually pretty inexpensive We were looking at the prices of free light chain and say it's like 150 bucks PYP scan I I tried to look at just I think it's 700 It's about the same as a stress test that we all do in our offices. You just have a different isotope And so all of us have the kit to do the testing. It just would be adding the isotope Yeah, you know, I think when we talk about treatment, you know I don't particularly think when I talk to the patient statin is the classical, right? I have 82 year old guys on statins Why even though the guidelines doesn't apply to patients over the age of 75 because actually I think it's unethical to give an 82 year old guy Statin and give him some my algeas, right? But I would still treat them based on their functional status if I now I want to just reduce their cardiovascular I think I think it's a risk-benefit ratio, you know when it comes I think we're all very frugal and very conscientious when we practice medicine And I think we want to offer the best for the patients when you look at the data on the families They actually have better quality of life, which is very important, right? Even when you're talking about the medicine and also reduce hospitalizations You know at the cost of hospitalization for heart failure, probably the most common DRG, you know for hospitalizations in the country So I think, you know, it's I feel a little warm when I talk about screening I really take your point very excellent presentation. Thank you You guys are too nice to debate. So our rebuttal is actually the same argument as you guys, okay? We did not know what they were going to say. We were not allowed to see their slides So I think at the end of the day, we all recognize that we have to screen the appropriate patient So we argue as you guys do that screening should not be geared towards only catching a rare disease in all patients You need to consider the appropriate risk factors Your screening should allow for the correct diagnosis of the underlying disease process as we've already said And if the patient screens positive for the disease, they need to have access to effective affordable and safe treatment options Um, and again screening should also take into account what matters most to the patient and their family And so Dr. Sauroff did an amazing job again educating the audience and I just wanted to kind of Reiterate and bring this point home that there are appropriate patients to screen and there's diagnostic clues to attr cardiomyopathy Very much based on our own history exam and then imaging as we've emphasized over and over again So again as a heart failure cardiologist, if I see a patient who has heart failure with preserved ejection fraction, you know, I'm Um getting my echocardiogram. I'm seeing what my ekg looks like again We've outlined kind of the low voltages in a thickened heart Um, you know patients who are not tolerating your conventional guideline directed medical therapy for heart failure Those neurological clues are key if you have a patient with lumbar stenosis carpal tunnel syndrome tendon rupture, etc And again as you go down this pathway, it'll be very important to make sure we're not overtreating or mistreating Hypertensive heart disease hypertrophic cardiomyopathy some of the other infiltrative cardiomyopathies The next several slides just focused on more of what's in the literature and diagnostic algorithms Um, it kind of really nicely spelled out From one of the CERC papers on the different pathways of cardiac amyloidosis. Oh, thank you um Let me get to that slide then So again, this can be a very confusing topic You know, I often have to remind myself to as a heart failure cardiologist like which type of amyloid am I dealing with? um And so this again is from a CERC paper and I really do encourage all of you to have this in your back pocket especially as there's more awareness for this disease process And you know, again, as dr. Soroff already said you want to really delineate the hematologic prevalent amyloidosis where we're talking about al amyloid versus the ttr amyloids and in the ttr amyloids You really want to make sure that you differentiate wild type From mutant because they're going to have you know genetic testing and familial sort of Implications that are going to be very important for our patients Let me see if I can go back to one of the slides Which one? Okay, um because there was another slide Um that I thought was important when I was putting this slide deck together and again There's so many different tests that are out there too and again It could be kind of confusing. Am I getting an echo? Am I getting an MRI? Am I doing this pyp scan that we keep talking about and that's where you can really utilize the help of You know your friendly cardiologists your friendly heart failure cardiologists your geriatricians Because as we learn more about the disease process these patients are complicated And we really do have to work together to make sure that we diagnose them appropriately and give them the treatment that they need I think you covered everything Ambulant to your point of sort of I I teach my fellows in residence What we're looking at life expectancy at this point. We're going to be looking at people 20 years More in regard to life expectancy And I think my point about screening everyone above the age of 65 is really that there is a big chunk which We really need to respect priorities what matters to them And understanding what is important to them and then make those decisions So that's really from us. Thank you. Thank you I want to make sure to Can you hear me now? No, okay So online zoom there's questions the same one as that's on the tabletop Please just answer those two questions and if you have feedback you can send those as well So, yeah, let's do um, is this mic on? Okay, um, yeah, let's do a little q and a for Um Five five minutes or so and then our judges will come back and give their feedback. So Um, go ahead and raise your hand and if you're online, uh, please post your question in the chat So do you have a question? So there were two questions. I'll just repeat it for online audience one question was um What's wrong with just starting with screening? To make a decision And the other question was how do you know that 4% is really the right percentage of patients? So let me defer to our panelists. So please Yeah, we we agree with your question excellent questions As I had said depending on which study you're reading right the prevalence is kind of variable So you're right in patients who are over 85. What's quoted 25 percent of patients Have some evidence of amyloid In their heart at autopsy So I think you're absolutely spot on now from an advanced heart failure cardiologist perspective like when we are screening that 90 year old It can bring some closure But again, there's a lot of fear with that too Of now you've been labeled with this diagnosis and depending on what their pre morbid Function was um, sometimes a psychological burden is extreme That's a great question. And again, I want to emphasize it's not really about age In no way I want to reflect that A 90 or a 85 or a 100 We really have to look at the person's frailty status and general well-being of the person when we are Deciding life and then the concept of life expectancy is important because When you're giving a treatment You have to understand the lack time to benefit That's another concept, right? If you are giving a treatment to a person who's gonna Benefit the person at the five month five year mark or the seven year mark And the life expectancy is three years Then are we doing justice? right um question to amber what is the usual time frame from The first clue that this could be amyloid cardiomyopathy and then the testing How long does that take? Yeah, I mean it depends on the center and it depends on the awareness At big centers, we might get patients who are in cardiogenic shock coming in with cardiac amyloidosis And it's too late on the other hand where there are centers of excellence for cardiac amyloidosis those patients may get Appropriately the tricky thing with that is, you know, the drug studies actually do show quick benefit Which drug we're talking about again at six months and the benefit may be persistent if you get those patients who are NYHA class two to three without severe comorbidities Yeah, so that's what I was going to say that the benefit of the drug therapies Unfolding of these proteins and actually allowing the nerves not to get the deposition Is so huge you can actually make a huge difference and 65 years old is really nothing in now We're living such a long life and the this this debate was 65 I get it for 85 But we're talking about middle-aged people who play golf and who are here in Arizona These tests these screening tests are not in the whole big realm We're screening everyone who comes in with shortness of breath with a CT scan to rule out pe on almost everybody We're getting we're we're doing a lot of testing and screening This should also be a screening test if you if you have the constellation of these symptoms And what you're finding on your labs and you have to actually think about it And that's what these educational programs are for so it's a question back here and then a question after that One of the one of the other considerations with screening Is if somebody presents With heart failure or with the cardiomyopathy And you think they have amyloid When you see them It's very difficult to know oftentimes whether they have wild type or hereditary without doing genetic testing So We also have to consider the children if they have them the offspring of of who you might be screening Because if somebody has hereditary TTR They they probably want to know that it's important for the kids to know that right so The only way that i've seen to reliably differentiate between Wild type and hereditary clinically at least have some sense of it is if there are significant neurological issues um Otherwise it's very difficult so Really i would advocate for Not only screening but the necessity of doing genetic testing particularly if they're offspring I think that's a critical factor in considering How far screening and then how far to screen in terms of genetic testing Okay, one more comment or question and then we'll let the judges present I want to just also point out that something that is not really life and death mortality or life expectancy Yes, it's debatable the frailty is the 65 or 85 the thing that I see a lot I'm advanced heart failure cardiologists my patient population.  They are smokers The creatinine is three. They have hypertension. They have shortness of breath. They come to see me And someone sometimes even in between and I thought about amyloid because it's okay. There was a lvh report on the echocardiogram and already they came up with a positive stress positive a pyps scam And they were thinking that okay. So why you know, this doctor is not treating my cardiac amyloid And my debate my presentation to them is that let's assume that you are positive Let's assume that that this is still is positive when your creatinine is 3.5 and you're hypertensive and your smoker treating your amyloid is not going to make you feel better and I think even it's not going to make you live longer because that's the two thing as a doctor I will do either are going to make you feel better or live longer You will die way before that You know the family is going to really work on you. So I think one of the things that I'm debating against Screening is that it's not about all this patient is going to die tomorrow. No this patient might be looking good Might have a five years of life expectancy or more But then has so many comorbidities You put the diagnosis of amyloid which is like fancier look Newer look more expensive medication on top of the something that you can easily treat So instead of stop smoking instead of let's give you some My fetipine to control your blood pressure or let's you know, make sure the nephrology is on board Oh, now we have amyloidosis diagnosis and we have to treat you for it Sometimes even I tell my patients, you know, I think that test is could be even a true positive But I'm not sure really I'm doing a service to you to even treat you for that Why don't you just go back come back and lose 20 pounds for me? Why don't you just quit smoking? Let's see what your shortness of breath look like because if I've treated six months from now Still you're at the same stage. So one of the things I also we need to emphasize Unless you're in a cardiogenic shock at the burned out heart Waiting for six months to treat in cardiac amyloidosis if someone is not having five types of hospitalizations And BMP is not like five thousand and troponin is not like two Waiting for six months not going to make that much of a difference. I would say one of the argument I have is that it just gives us False hope that by finding a diagnosis and treating that it's going to take we got to take care of the main problem Because you know, cardiac amyloidosis is famous for having given you shortness of breath But there are other things put potentially causing that No, no, I'm talking about when you have shortness of breath It's a lung cancer is different the cardiac amyloidosis Is not going to kill you in six months Unless you're in a very end stage, which probably you shouldn't even treat that because then in that case the family This actually defies the purpose because if you're stage four Giving you to family. This is kind of it's not really useful for you So if you're just having some symptom you think this is amyloid you have six months to think about go back and forth Treat the underlying cause I'm all for improving quality of life But I would say first let the patient walk more eat less quit smoking.  So it's my turn now So this is it. This is exactly what we wanted. We wanted you guys to debate amongst yourself and you're doing This is fantastic. Are you guys having fun? Isn't that the team a fantastic team be even fantastic or You know, this is it right in a debate. This is exactly what happens, you know One team does good in something the other team does better than some other So we had some way to essentially quantify Some of these measures and so we looked at content the accuracy of the content we looked at the the use of Of sound logic and then in the delivery we looked at the voice the posture the gesture the The eye contact we looked at the effective use of time We looked at teamwork in your presentation and then in the quality of slide we looked at Whether they were too busy whether There was a you know good audio good visual and whether it's relevant research whether they've cited Beautifully in almost every slide that I saw for team a and then the analytical thinking. Oh my god Did they do a good job in terms of their ability to focus on the critical issues? In our lifetime across the board and you heard nimeth Kind of showing those beautiful two slides and dividing the old age into three different categories And I thought hey old age is just old age and here suddenly we are learning something brand new From him and then we suddenly we looked at the logical and the coherence and the and the development of the argument itself And and the smooth transition from one to the other And then all of this when we put it all together and both alexis and ivy scored it together We thought hey in one of these criteria team a did good the other one team b did good and the quality is like a team did Oh the analytical thing team b did good when we scored and actually measured it because what happened out there Will become no hold on we'll come to the rebuttal Now the rebuttal had separate scoring system And and and and both teams really had some very powerful thought process and and to to really summarize the rebuttal uh, I thought and both of us thought that That that susan you brought up something futuristic She talked about gene she talked about the gene editing that she talked about newer therapies that's coming We talked about hey at with time we know that all of these medications that cost us an arm and a leg Uh, we slowly now coming down with time and as you mentioned Oh, what if the famine is with $5,000 now would you screen more people right? So many of this is all related to all of that relation You brought that up beautifully and then when you did the rebuttal amber and and and limit You guys are fantastic in bringing up my favorite topic quality The quality adjusted life here. What a beautiful statistical terminology, you know The cost per quality was fantastically mentioned So in a sense it looks like my god, you did good. You did good There is debate going on even now at the end of all of this between the audience and the audience scored and we calculated that too And and we found Something very powerful something very important. So It is an african proverb When two elephants fight It is the ground that suffers Number two When you have to debate You have to convince the audience, but many times you have to do it by confusing the audience And I think both of you did that beautifully convince and confuse and convince again and thirdly As Woody Allen would say if he's standing right here He would say when you get to a crossroads Take it So we are at crossroads Why because the debate essentially was a topic that really didn't have one single answer yay or nay And with this debate you could go this way or you could go that way And both the sides essentially boiled down to saying that yes We had to use caution in the screen the elderly patients who have heart failure And in a sense we found the same thing the scoring system with all of this category Absolutely even and guess what the audience score was 50 50 So in a sense who benefited from this debate The patients are benefited and the audience have benefited and all of the people who have learned about the awareness and the knowledge Have benefited and I thank you Suzanne and Michael and I thank you amber and nimeth. I think it's fantastic Thank you for coming and thank you for really getting this together for all of us and supporting From the bottom of my heart and thanks to Sandesh for bringing us together Thank you so much so This includes our wonderful evening and now we're going to hand out the prizes to the the winners So You have your booty bags So thank you very much Thank you. We're really honored For your participation and your brilliant insights And I have to say it's it's amazing how far we've come you guys have really are great students of medicine. So Um, I really thank you for for pulling this off And we look forward to seeing the rest of you on november 8th for our next event Um, if you have any suggestions, uh, please let us know So thank you so much. So this ends our official, uh event, but happy to stick around Thank you Thank you And the questions were amazing, but you can't explain those heavy concepts in five minutes


Now, other ways to assess the cerebellar function would be rapid alternating movements. So place your hands on your thighs, please, and now turn your palms up, and then alternate between palms up and palms down really quickly. Okay, very good. So that's rapid alternating movement. So the other test for rapid alternating movements, I'll have you touch your thumb and your index finger of both hands, and then touch with your thumb the middle finger, and then the ring, and then the pinky, and then go back and forth, and do that very fast about 10 times. Okay, thank you. You can stop. So for the lower extremities, I'll hold my palm behind or underneath your foot. Tap your foot down on my hand, please. Okay, go ahead. Okay, very good. And now let's see the other side. Okay, thank you. All done. And that is the rapid alternating movement of both upper and lower extremities.


Where in the world is that? Well, I'd like to research for you by DigiKey and Antipir. Thanks to DigiKey every single weekly day, user power of engineering, to help you, yes, you find the things you need on digikey.com later. And what are you looking for on digikey.com this week? Okay. So, sorry, some of my notes behind the scenes. So, I take notes before the videos. So, this week, well, first off, I wanted to point out that the DigiWish 2023 is running right now. You can get free stuff. I can't get free stuff. I'm not eligible. The biggest tragedy of doing stuff with DigiKey. But that's okay. You can get stuff for free. All you have to do is post with the hashtag DigiWish on a variety of social networks. You can do one entry per day. And the thing you have to request is $100 or less. I have a lot of Adafruit stuff that's stock. That's $100 or less. I get like a PPK. I saw some people looking for wire strippers. Pick something that's like, you know, $80, $90 range and post up and they pick one person every day to get free stuff. And they've been doing this for a very long time. This is actually one of the oldest social media events that DigiKey has done. So, I've never won again because I'm not eligible. But I know people who have and it's a joy to get something for free. So, check that out. So, this week, I saw we got a request for somebody who was using a Raspberry Pi and they were using the Raspberry Pi 5 to do like continuous data logging and video. And they're like, well, what microSD card should I use to make sure that I don't have failures in the field, especially if you're using it for industrial purposes, you're going to have this Raspberry Pi outdoors or it's like, you know, part of a mobile or seafaring data logging system. The most delicate part of the Raspberry Pi is definitely the microSD card. You want to make sure that's well-specced. And they said, can I just get like a microSD card from online, whatever, e-tailer. And I said, well, if you do that, you're going to, you know, they're inexpensive, but they're not designed for industrial use. They don't have guarantees for how often you can write to them. Can you write to them continuously for a very long time and how many years and temperature gradient. Also, I found a couple other kind of funky things that you can get with microSD cards if you get them like industrial style. So, let's go to memory cards, just click on memory cards. So, let's just only look at active because, you know, just minimize the number of options to search for. So, like I said, DigiKey stocks a whole bunch of SD cards. They're not going to be like the inexpensive, like two bucks a piece.  These are definitely going to be for industrial uses with single board computers. And so they're going to be more expensive, but they're going to have more guarantees and a wider temperature range. So, the first thing to check for is what class you want. So, the class is basically how fast you can write and read from the microSD card. You know, you can check Wikipedia for a full document of every class setting, but basically the higher the number, the better the class. And once you get to class 10, there's like subclasses. So, class three is going to be the faster. I think it's about 100 megabit per second read and write. And if you're doing, you know, video or AI data reading, you want to like buffer to, you know, you're not using RAM for your buffering, you're buffering stuff to disk somehow. You should definitely get class three, which is also going to be called U3. Class 10, UHS3, U3. So, it's going to be the fastest. And oh, wow, you need like one terabyte for real. Geez, that's expensive. But you want a one and a half terabyte guaranteed class 10 U3 SD card? That's cool. Anyways, you can order them. But we're not going to get a one terabyte. We're going to get, you know, 8.16 or 32. So, let's look for that. Okay. So, there's a couple options available. A couple of vendors. Each vendor is going to have their own thing. So, first up, let's just do normally stocking. Okay. So, all these are going to be micro SD because that's kind of what you're going to get. I did notice a couple cool features. So, ATP, they had a guarantee of five years or two years with also, you know, documented reliability for insertions and also mean time to failure. They also guarantee their sequential reads and writes, which is kind of nice. Of course, if it's not sequential, if you're like jumping around, it won't be the same. And there's also ones that are, so you can see all the different options, and there's a slightly less, slightly lower warranty, three years, not five years. There's also, let's see, was it APACER? I saw one that had, let me see, silicon power. It had a guarantee for if you had power lossage, it would like actually be able to recover from it. But even like things like, you know, the amount of current draw, like that's actually unusual, like for low cost micro SD cards, you're not going to have guarantees for that. Guaranteed, humidity, guaranteed operating temperature. They have ones that go negative 40 to 85. These are good for outdoor use cases. And try to think what else. Yes, some of these have like guaranteed for random reads and writes and bus mode. Oh yeah, power failure management, which I thought was kind of neat. So, you know, some of them have extra error correction, power failure management, guaranteed that not only will they do wear leveling because all micro SDs do wear leveling, but they will do like even wear leveling. And they'll make sure that like you don't reuse the same area multiple times.  So a lot of options mean you'll want to check, you know, what is the size that you want. But, you know, even something like this one, UHS class 3, and if you need, actually let's go look at a temperature range for select one. So let's maybe pick one that does, you know, that full negative 40. And then, yeah, this one, for example, 500 in stock, and also some of them I noticed, they will guarantee supply. So if you register with them, they will tell you if they discontinue the card and give you a last time buy. So if you suspect a card for your use case and you're like, okay, I don't want to go and respect other cards, they guarantee that you'll be able to supply you for at least like a year past the end of life date. So check out some micro SD cards for industrial use. Again, not, you wouldn't get this for your switch. You'd get this for a single board computer or something that's outside or doing data logging. You're sending it to space. These are some good options. That's my great search.


Welcome back. This is SPM Barz Kenyans number one online media station. My name is Seva Kido. Today I'm being joined by B. I'm on my tour guide. We're going to be here. We're going to be here. How are you? I'm doing good. You guys are excited. I can tell the suitcase is full. We're going to be here. I'm going to tell you what's going on. We're going to be here. This is Australia. Australia. For the Australian juice party. Juice party? Yes. Right. I've been joking around. I was on stage three years ago. We were together to look at a story. We were in the same group. We wanted to go to a place called Bogota. We met eight years ago. We had a flu. Tuna wuka mabahari. Mabahari. How many oceans are in the ocean now? Actually, tu taku wa tukwa Indian, lakini nani distance. Ah, zi. Eh, julazi ma twingi e kata kidogo, then tu wuke Pacific twende Hong Kong pale, alaftu rudi Indian tena, twingi wa api twingi Sydney. Sydney. Okay. Maybe you can tell us, how were you prepared for this juice party too? Mimi Pandiango, kama, hiz, K.Y.M. Even the rest of them, mga mini K.Y.M. So, I say I'm on stage. I see you. Ku vigia wa tu story. Mimi, bila nimeji prepare, ni kumprepia e, kuhakisha he's ready. Aki kete kwa yu kiti, nacha pa shumoja, fire. Yes. Bana, okigepa le YouTube utapata, nimi piga almost 400 stories. Izo zote maze, e indio culmination. Izo zote maze, Izo story. Izo zote nime kele, kumitandao, e li kwa zoezi, e isu glitu nanda kupiga apam. The very crucial kwangu sababundio, the very first time na piga, 2 and J.A. Borders. Sosiezi nanda kupile kazi vivi uko. Lazima tu vuru gemba. Bile suyu fanya. Kido ona jua? Mamboa ku atari. Mamboa ona jua? Kabisa. Do you feel pressure now? Of course, everyone is watching you. Going to Australia. Performing, representing Kenyans. People are looking forward for an amazing experience. Do you feel tense? Kido go a bit? Kila mtobida, nilzebun na nao ambia. The moment I stop feeling those butterflies in my stomach, that's the moment I stop doing what I'm doing. Sababu bina manisha ita kwa ime achakuni, da kwa ime achakui feel. Izi butterflies nani sho, bado tukondani bro. So, the reason why butterflies okam nijuna takaku deliver the best. Ilesku butterflies ita ntoka, da jua ah. It's not a big deal anymore. So, niza nda hukon ni pige sho moja ifi nani rudi tu, juicy feel. Lakin ni by then, the butterflies zikiwa una jua bana, you're still doing it from the heart. Da yon do important maze. Of course, in a moment, how are you prepared emotionally, just to control yourself, to come down, to make sure that everything is all planned. Skit in hand as planned, everything is going as prepared. Mi waga nambia, silver bullet, ni ile story nani nakupiga. Story nani mi ndani fire. Ni story atari. Ani atasai muka kuatuna ida ni wapigie moja apa, amtatoka apa. So, the fact that na joni meji amina good stories, yo tarini shapita 80% of the exam. Yo ingine tu ni presentation palen, ni looku ikubali ni ni ni ni ni. But 80% tarik ondani. Naka, weinim tu me piga kitabu na jyo 80% ni ae. Yo ni ae me smama. Ae maze. Of course, Kenyans nubali, they want to know, they want to be part of the journey, they want to see, apart from you posting on stories. They want to know how did the show went. Are there options, are there maybe streaming platforms for them just to be part of this amazing show? Are there plans, maybe to go on a live palen, puwa kiwa show? Z. Streaming no. Kus this one is purely for the Australian people. Ii ni wao tu me nda juyao. Kuna family Australian, kuna friends Australia, kuna friends Australia jamani, ata 60 ni misha biki pia. Wacha wawa Australia wa tibana. Sinkitu pa tia Nairo bina ka, bina Nairo bina ka. Iinia Australia. So this one is for the people who will be there. Exactly. Ata sayi bina ki vuru ga uko amoni yosho. Muna na tu afta. Muna na tu tu snippets kum tandao. Hi ya tu ta wa njima, snippets tu ta wa peya. Kum tandao tu ni ni kidokidoku kusumbua once in a while. Ita happen. Just to mention to the viewers of Espemba and Nairo BTV, you are being joined by, is it a family, are they friends, business partners? Bode guys. Bode guys. Bode guys. Bote yu kohapa, sele wa kabine yu kohapa, yu kusya kohapa. What is the feeling to see your friends, your partners, family, being here just to wish you all the best. Iwana, kawa iwenim sayo, me kukitu fota foda olong, wana juya bana, anima day once. Isa mai day once. Wata tu tu me tokanao umbali tu me jenganao witu kubu asana. So, awa kwa na chois, na zimo wangeshoa. Na zimo wangeshoa. Na salimos. Salimos. Salimos. Ako area salam. Titu moja tu limpa tia liwa utia kwa tokeleo ni filo, filo lewa kwa daddy duties. So, waga, weekendi waga di. Shiki. He's on the sacred for him. Ya, but he's been represented up a deadly sana. Wijana wangu wawa, ispoku wa, Timo Rizuna, menileta ni juo. Ono kijana naga gari. Ono kijana naga gari. Sa, anata kuni katia ni muwachi e ii. Baduna deliberate, siko shuwa sana. Pengine ni ongetu nangongo spale. Tisele akiwa ni kuna imani. Bila wiyo, ah, siyoni. Jumus. Utajutatia kwa bantigani. Utajutatia kwa bantigani. I just wish them all the best. Nishi na mabaya, wajende vizuri. Kabiza. Siyoma ni acha na agari. Abel, one word to your fans, to them kuru that are waiting for you in Australia. Kabiza, man. Um, guys, eh, tia tia acha ikuja shuwa e tuwa na juwaga bana. We stand on business, man. Sisi waga tunna pati aiki 250%. Ili experience you pati ya wa tuwa na irobi up and your experience tunna ta akuleta palia Australia. Akuna kukuja nama shuwa tia mani ni, we must give you the absolute best. Sababu the fact that ni niwe niye mu me kachini, mu kase maawa tuwa token Nairobi wakuja all the way to Australia, kizatu story. Mani ni na mani siya kuna maili mu me tuwa eka. So it is our duty to make sure that we live up to it at ways iwa angusha. Come through, come out jashikati ko eventbrite.com.au is where you get your tickets to jibambe maze. Shuwa kwanza ni Friday, ya pili sato, ya tattoo ni next week on Friday. The Easter weekend. Yes, ya nne Saturday, ya tano Sunday. Sunday. Ya. Kuru? Eh, I think ni kakuri kaptu kenya. Mestaki kuru dia, but we just telling our Australian peeps. Like we are coming to give them the best show they've ever experienced. And we are ready. We are ready. Thank you so much for your time. I wish you all the best. Hope to see you back. Yes. Na to see you pia kido maze waga una tshikili amkono sana maze go dakublesana. Ramadan Karim, my brother. Mjelle lazima tu kuji e. Na kusai futari SPM. Aa. Ita kwa tu ki wa tu ko inje? Butita tu liongi aiki tu bana. Hei bana ni kirudi lazima tu kule wali wali matobosha matobosha nini. Hei mbu zijini pale. Osiji chapati bandia zini. Lazi ima bana. Iwa eze kido. All the best. Asanti. Asanti. Thank you kido. Asanti. Tuna appreciate. All the best. Thank you so much. Thank you so much. Asanti. Wachatu rukendani wa down. All right.


Hi everyone, Sean with jaspyscasebreaks.com here doing 2021 tops chrome baseball jumbo eight box case break pick a team number three we're all card ship so um this is our customer list respective teams from Sean Breen and the Dimebacks down to Sean Maddock and the Nationals if you see anybody with a little rooftop next to their name you shouldn't see 10 of them that just means they won that team in a team random filler which we have uploaded that random that video separately to show the results of that but here is that list in person and here is our case first part of this video is just going to be me ripping this case open and stack pack stacking i just noticed i did not upload that video so let me upload that before i forget because then we'll run into issues later on okay so like i said first part of this break is going to be just me pack stacking this entire case um if you are watching live you're stuck with me if you're watching this at a later time uh just scroll forward until you see me obviously not stacking packs anymore and actually going through the cards uh and then you can pick it up from there to see the result of the break okay so when you make case of Joey do you uh do you use like do you just do like a store bought one or do you make it from scratch and if so which one do you use i love case one too one big chips and salsa guy no store bought as far as like really good then and then second follow-up question share the deeds dude i need the family recipe pepper jack cheddar and anion chilies that sounds very good store bought for you rebel there's this really good uh restaurant in old town orange in the plaza um called gabby's who has this really good case of fundito not only is it fun to say but it's delicious except for they put big old mushrooms in there like long like not like you know thick mushrooms but like the long mushrooms the girlfriend likes their jalapeno margaritas i like all of their stuff with alcohol in it and their food but like store bought i feel like if you're going to get by case with store bought you only have the option of like the uh postitos one just kind of boring you know for lack of a better words plain and boring and like you know like made for like boring people don't get me wrong it's delicious 13th inning in the Dodgers Padres game i feel like it's like do or die for the Padres that they're gonna have any chance right that makes really good white case so i'm not sure the place is gonna be shut down aw that sucks oh well then yeah that kind of sucks even more i don't think just i thought they just busted them okay well then that's back food distribution center well that's not good yeah that's a that's a lot of stuff i think worse than just the smuggling uh this is a tops chrome jumbo hobby uh tops from jumbo casebreak brick eight boxes got five open this is number six got two more to go yeah i mean the thing is if he's if he's documented then yeah he'll be looking at time if he's not they'll charge him and then they'll deport him and i don't think i don't think that like once you're ported i don't think that they would um i don't think that they would imprison them into whatever country of that is though you know uh this is a full case eight jumbo so 40 autos 41 if we get the captain's cloth auto in this case once i get all of them open that's when we'll go through them i think he gets his jersey let's beat two out show that replay again cool and box number eight remember all card ship good night dude hey thanks for that stuff let me know i will uh if you like it i'm trust me i'm sure i will especially the tequila i can see some orange already that's a good sign good luck everybody nolan aeronado for the rockies and our first auto is dame dunning to 150 for the white socks and eric ainge kyle louis for the mariners nick solak for the rangers ryan mount castle for the orioles and clayton kershaw to 199 for the dodgers travis melberg anderson taheda for the rangers hasus lasardo for the a's and evan longoria for the giants luke voight for the yankees alex curelaw for the twins erin judge for the yankees and dalton jeffreys rookie auto for the a's ben scripok kettle marté for the diamond backs mike bruceau for the rays kasey mys for the tigers deedy gregorius for the fillies brice harper for the fillies tautis for the padres and our third audio is alex evesia for the marlins and icapola max freed for the braves bobby doll back for the red socks still in carlson for the cardinals david orteez red sox william contreras for the braves and ryan brawn for the brewers kyle louis mariners and kate ryan haves for the pirates christ archer also for the pirates red or sorry orange wave to 25 and devin williams for the brewers christian pashé for the braves mani machado for the padres and louise garcia auto for the astros icapola alex for dugo for the red socks joey bart for the giants alex bohm for the fillies yas money grand doll for the white socks and dylan carlson for the cardinals jack flirty for the cardinals joe adell for the angels yordan alvarez astros brandon woodruff for the brewers and louise gonzalez our fifth auto for the white socks eric ange porre salaire for the royals luke voit yankees joe adell angels mookie bets 2.99 for the dodgers and travis melberg and ian danerson for the braves shan't we have any more quality packs over here in this room? um not that i ever saw in here or none that i ever you know would have brought over here so one two three four five all of those box one down box two tyler stevenson for the reds and our first auto is andre scrub for the astros icapola alberto mondacy for the royals i'm actually surprised we were talking about this today with nick i'm surprised these face mask cards there's a couple of different players that have them are not short prints but that's their base cards mike brousseau for the rays mike trout for the angels and shin su chudan 199 for the rangers donald dudley and yadda ermalina for the cardinals hasus lazardo for the a's six dough sanchez for the marlins john means for the orioles christian pache for the braves joey bark for the giants tyle lewis for the mariners and tyler stevenson to 199 for the reds auto jeffrey lobota carlos korea astros rubble rubble what if they did a uh a george brett like sprinting out of the dugout short print that would be pretty cool like full sprint out of the dugout alec bone fillies joe dell angels hasus lazardo a's walker bueller dodgers masahiro tanaka yankees nick madrigal white socks rafael devers red socks kibriane a's pirate and dalton varshaw auto for the diva backs shon breen paul deyong cardinals david orteez red socks kevin newman pirate runeto door rangers i guess some more orange coming up it looks like another orange wave maybe jordan astros wan soto nationals and illoy orange to 25 for the white socks eric ainge orange wave and lordus guiriel for the blue jays yeah exactly dana exactly no but like him charging full speed out of the dugout would probably be the coolest i'd have to have that card tops make that card or fanatics make that card dak rankee astros and franklin kilome gold wave to 50 10 out of 50 for the metz howard ton team he won in random kentamaeida for the twins ryan mount castle orials you guys monday grand doll white socks brady singer for the royals mic trout angels nick solak rangers shogakiyama reds and louis basabé for the giants lee cheeseman jake kronenworth padre's brian peoples garrick kohl yankees kasey meyes tigers whorel faro marlins i just think it's funny that like it wasn't him like charging the mound that got him in trouble it was him trying to sneak into the umpire's locker room to steal back the bat or is that a different situation see howard you get a gold auto already one two three four five box three oh see look at you tristan mckenzie for the indians and tj anton auto for the reds jeffie lobota jt ryan mutto fillies willy castrow tigers jake of the grom metz and david peterson to one or to 75 for the metz and howard tonk uh cavin bgio blue jays christian pache braves joey barth giants wan soto nationals john means orials brady singer royals alec bone fillies joey del angels sisto sanchez for the marlins second auto is tyson miller for the cubs gregg mathebia trying to find some uh no i'm leaving you some boxes for fillers cool thank you chris sale redsox nick madrigal white socks bobe shet blue jays carlos korea astros william contrast to 99 for the braves mathew shira kevin kirmeyer for the race jake kronoworth padres lup voit yankees nolan aeronado cardinals and kyle cody to 150 auto for the rangers donald dudley and danby swanson for the braves porre fissada yankees chris sale redsox nick castiano reds shon murphy a's ron wakuna jr braves and alex kirloff nice one it's a 350 for the twins and steve lock and sisto sanchez for the marlins wait a second if they do that howard then they're gonna do one for joe dell and that just that just hurts me because i'm an angels fan ryan mountcastle orials nick castianos reds and edwin olivarez rookie auto for the royals and brett martin rafael devers for the redsox hosel two ve astros zander bogarts redsox brandon woodruff brewers trenk risham padres jake bigrom metz and jared oliva to 250 for the pirates darin mckenzie trevor story for the rockies is that trevor story bass card it is some of this photography this year is so good louise castillo reds joey bart giants and nick madrigal white socks uh some of the photography in these bass auto or bass cards is so good this year they look like they should be short prints box three thanks guys have a good night uh yeah i'll see you tomorrow uh you're starting at three right okay cool one two three four five christian pache for the braves joey bart for the giants mic trout for the angels and all of the redemption so far have been really good because they're really good names it's keegan aiken orials i stand corrected uh multiple orials that is erin billingsley aroldus Chapman for the yankees alec bone fillies joey dell angels gavin lux dodgers joey bart giants and lance mccullers to 399 for the astros louise campesano padres glaber torres yankees brady singer royals miguel cabrera tigers jacob de graham metz jonathan aroos to 150 red socks ryan depuy and louise garcia nationals just this year totally forgot about them you have two brett sp for this year rebel how'd you even get them i don't even honestly i don't even know what the george brett sp looks like from this year are we talking about is it in chrome he didn't have an sp in chrome does he the sp checklist is pretty short for chrome that's a that's a problem everybody has so don't don't feel too bad i keep telling i'm gonna get my cards organized and then somehow i get more cards and they don't get organized and either do the ones that i already had so nicole horner cubs chris sale red socks and shun yamaguchi to 99 for the bellugees okay yeah i was gonna say i was like he doesn't have one in chrome uh zander bogarts for the red socks cody bellinger dodger six dosanchez marlins and matt foster for the white socks eric ainge auto ozzy albie's braves ryan mount castle for the orioles yoneman kata white socks jack peterson dodgers and patrick corbin nationals uh jose or kitty astros petalanzo metz and shun yamaguchi to 199 for the blue jays and bobby dolbeck uh blue jays i capola only six dollars rebel how much would a regular brett be worth looking look at it in comparison jose ramirez indians umberto mejia for the diamondback shon brine and yoneman kata for the white socks bobby dolbeck red socks latimer guerrero uh blue jays ronda kuna jr braves and clark schmidt yankees dillan carlsson cardinals zack gallin uh diamondbacks kenta mayeda twins dame dunning white socks eric ainge branded lao reyes wilson contreras cubs zander bogarts red socks glaver torrez yankees kunya second year chrome short printer factor just laying around jeez dano that's not just a short print um if it's chrome short prints in chrome like this they're only in refractors so that'll help you limit your search if you ever end up having to find short prints in this um so far when i did uh between sunday and monday i did nine cases of jumbo um the case hits seem to either be one short print or super short print or a um or one of the captain's cloth autographs one two three four and five so we're only halfway dano only halfway erin judge yankees trevor rogers for the marlins icapola and ryan yarborough for the reyes randy raiser reyna reyes sexto sanchez marlins and marco gonzalez to 399 for the mariners ross gimble tarks google tigers twig like a toy for nanotatis junior padres joey vado reds joey vado reds nolan aeronado cardinals and ashton gudro for the rockies that is ryan dupuy and javi bias for the cubs yeah and then obviously there can be short print or image variation like the short print um like um color but i mean you should already have those top loaded or sleeved at least in the first place you know christian pashé braves brendan mckay reyes javi bias cubs chris paddock padres joey barb giants alec bone fillies wilson contreras cubs louise garcia nationals anerson tahada rangers to 150 that is donald dudley and ryan mount castle orials erin billingsley like a really small pack you go away nick madrigal white socks ron wakuna jr braves carlos korea astros witt maryfield royals jake kronoworth padres tony gonsolin dodgers zander vogart's red socks shirt and a postal to 199 for the rangers donald dudley and alex braggman for the astros runeto door rangers and sterling shark for the nationals to 250 shon matta jake bigrom metz wong gonzalez rangers joey barb giants and josh hater negative for the brewers david duffy and tristan mckenzie for the indians bruce star gratterall dodgers victor robles nationals zach mckinstry dodgers travis melbert and willy castrow tigers ryan mount castle orials riz huskens fillies jake bigrom metz josh dollison twintons witt maryfield hit a grand slam today and still lost dude witt maryfield is so good love that guy rebel you know some some gritty players like low-key guys that just don't get enough appreciation uh witt maryfield riz huskens nick castianos those three i'll take those dudes on anything obviously big castianos isn't so much like he's kind of popped out a little bit but still one two three four five yeah well it's like um it's like joey vato when he was on that home run streak um that home run streak where like he had hit a home run in like seven straight games or anything yeah salvador pares i it's hard to say that he's underrated or like just under the uh like because he's so good and he's still one of the highest paid catchers there is it's just he plays for you know the royals so it doesn't get any attention um but that uh when when um vato was on that home run streak that one that missed the home run by like two inches that would have been a home run in all but 10 stadiums in the league it was pretty crazy so we missed an eight home run streak at least chrono worth padres yon mancada wipe socks pyle seager nationals dalton varshow for the diamondbacks jose or kitty astros dylan carlsson cardinals and evan longoria to 399 for the giants and the chiefsmen andrew mccutcheon fillies keever ruiz dodgers and our first auto is roelle ramirez for the cardinals matthew shearer louise castillo for the reds alex kirilloff for the twins lab guru uh blue jays joe angels wilson kontreras cups zack gallin diamondbacks rudetto door rangers kasey mys tigers to 150 nice blue wave auto tigers jeremy taylor and walker buller dodgers k ryan haze pirates jose ramirez indians ryan mouthcastle oryals shin suit chute to 99 rangers donald dudley and ryan weathers padres lordus guerrilla blue jays jared oliva pirates darren mckenzie nullan aeronado rockies gavin locks dodgers erin judz yankees biren buxton to 299 twins steve lock chris bryant cubs glaber torrez oh jazz chism marlins glaber torrez yankees dean kramer oryals and louisa ria's twins bobby dollback red socks fernando tuttees jr padres and yohan ramirez auto for the mariners ross gimble lance McCullers astros dylan carlson cardinals nick nico horner cubs john carlo stanton yankees willy adamas rays illoy white socks petal london metz and sisto sanchez auto marlins icapola trevor bauer reds one two three four five showing up today i mean in the break we just haven't seen any color or anything of him yet all it takes is one super fracter right yeah it's on kibri and haze pirates john means oryals and jordan halloway to 499 for the marlins icapola shinsuchu rangers devin williams brewers christian yelich brewers and anthony randon to 350 brandon latubipa tanner hawk red socks edgar martinez mariners mikey stromsky giant shirt and apostle rangers jazz chism marlins andres amenes indians erin fletcher marlins ross gimble aj puck a's bobby dollback red socks thyle louis mariners david peterson metz hyunjin ryu blue jays dylan carlson cardinals matt olson a's shohio tani angels jt brew baker pirates that is jaren mckenzie and mike clevenger padres nick madrigal white socks dalton varshow diamondbacks joe dell for the angels kettle marté diamondbacks christ davis a's and justin verlander astros jake kronoworth padres louise robert white socks louise robert white socks and cody bellinger that is a short print i believe out of 99 that is actually his short print yeah uh hard to see but the numbers on the bottom are number 350 so one out of 99 cody bellinger short print dodgers travis melbert team he won in the team random there you go chris archer pirates very nice garret coal yankees cody hewer white socks erick ainge max kepler twins he might be hitting like shit this season that's a really nice card rod caru twins jade kronoworth padres and dallas kykel white socks dylan sees white socks ryan weathers padres and josh fleming for the rays auto tom jones and kevin kevin newman for the pirates trying to say kevin keermeyer was not him alex keerloff twins cody bellinger dodgers alec boom fillies and bryce harper negative refractor fillies daniel auslick and zack rynke astros that's why you gotta buy him at howard it was a hyper right or no the it was the 86 or whatever what year is that one this year yeah 86 that harper negative should be pretty decent too dan he's having an incredible season this year but i was as i was saying earlier he's probably going to get runner up for a for nlmvp um glad he'll get runner up for nlm or for al mvp and then you'll have tatis and um tani with the winners right so it's just like i when was the last time you had the winner and the runner up for mvp's teams all missed the playoffs it's pretty crazy last box guys another five autos and close it up or is a passata or a passata yankees clayton kershaw dodgers hosea remeer as indians alex kirilov twins shon murphy a's nolan aeronado cardinals tim anderson the 250 for the white socks eric angel sorry 299 auto purple 250 and christian javier for the astros nelson cruz twins taylor whitner diamondback shon brine and leotie toveris rangers hosea al-tube astros louise garcia nationals will mire padres nick madrigal white socks tranq risham padres paul gulchman cardinals set l ridge to 499 cardinals auto matthew shira byron buxton twins jay chronalworth padres jazz chism marlins matt olson a's louise robert white socks edward eskibar eduardo eskibar diamondbacks what the hell just happened oh wow hosea brie white socks rafael marchand fillies uh that fillies is daniel ousley and blake snell for the raise willy castrow tigers jake chronalworth padres just got caught in a rundown between third and home in a 14th inning game now and kentamaeida for the twins to 350 steve lock no cinder guard for the mets and last stack should have two more autos in here wan soto nationals masahiro tanaka yanke soze brie white socks alec boom again fillies uh horre guzman for the marlins that is icapola jock peterson for the dodgers k brine haze pirates bobe shut blue jays paul deyong cardinals buster posie giants rye mount casser cardinals we've got orange wave to end it that'd be our auto garret coal yankees christian yellich brewers and it's zack birdie white socks orange wave auto that's to 25 for eric ainge eight out of 25 and he has money grand doll to finish it off there you go guys that is the break uh i'm gonna pause the video we'll do a quick recap and close it up you're right back uh so we're back uh recap out of 25 zack birdie white socks rafael marchand fillies taylor weidner dima backs set alridge to 499 cardinals horre guzman marlins jt brew baker pirates erin fletcher mara mariners josh fleming ray's jordan halloween of 499 marlins kody hewer white socks kasey mias to 150 tigers yohan ramirez marlin or mariners roel ramirez cardinals jared oliva pirates sisto sanchez marlins zack mckinstree dodgers uh sterling sharp to 250 nationals anderson the hater to 150 rangers trevor rogers marlin ashton gudro rockies dame dunning white socks humbert domahia dima backs matt foster white socks and keegan achon for the orioles jonathan aruz to 150 uh red socks jared oliva 250 pirates edward olivaris royals kyle kody 150 rangers tj anton for the reds tyson miller cubs franklin kilomate to 50 for the mets louise visabe giants dalton varsho dima backs tether students in the 199 for the reds andre scrub astros louise garcia astros louise gonzalez white socks alice vessia marlins dame dunning to 150 white socks and dalton jeffreys for the dima backs and our photo variation image variation short print to 99 kody bellinger for the dodgers and there you go guys that is the break that was 2021 tops chrome baseball jumbo eight box case break picatin number three from jazby's case breaks dot com i'm shon jazby's case breaks dot com thanks for hanging out see you next time