You know I've mentioned over and over again about how much I appreciate the Transformers community. Whether it be YouTube or Facebook, I love this community. Granted, we have the occasional troll every now and then, but 90% of our community is full of great people. And let me give you an example. Last week, I reviewed Siege Soundwave. And during the review, I mentioned that I found the figure, but I couldn't find Ravage and Laserbeak. And when I canceled my pre-order for this figure, I lost my pre-order of Ravage and Laserbeak too. So I thought I was screwed. But a viewer of my videos, who's also a Facebook friend of mine, got in contact with me and said that he knew a guy that had a Ravage and Laserbeak. So he got me in touch with this guy. This guy got in touch with me, yada, yada, yada, back and forth. As a result, I now have Ravage and Laserbeak and the Rescue Squad. So big shout out to Mike and a big shout out to Tim for selling these guys to me at cost. No scalper prices here. I got these at cost. Thank you very much. So for this review, it's time to get alarmed and take a look at the new Rescue Patrol. And welcome to Patriot Prime Reviews. The first thing we'll do is take a look at the packaging. We see red heat and stakeout in robot mode. That fantastic siege artwork on top depicted them in their vehicle modes. Transformers to caratomy, transformers along the side. On the back is your product shots and shows their vehicle, robot and weird weapon mode. Yeah, can't wait to see that one. But anyway, there is the packaging for the Rescue Patrol. Now let's take a look at the robots inside. Now let's start with the Rescue Patrol in vehicle mode first. Now when you do first open them out of the package, they do come with a nice set of instructions like the rest of the siege figures. That is very well illustrated. So transforming these guys will be no problem whatsoever. But with MB MicroMasters, it's no big deal anyway. The two figures you get with this set is red heat, the fire truck, and stakeout, the police car. And we'll go ahead and take a look at red heat first. Red heat is a Cybertronian fire truck and a remold repaint of the MicroMaster Battle Squad member, Top Shot. But he's not really that good of a repaint or retool. Top Shot is one of my favorite MicroMasters. He's got great paint applications, fantastic molded detail. I mean this is a great looking vehicle. Top Shot, not so much. Prime example, look at the paint on the windows. On Top Shot you can see the black painted in windows and the outline frame with the windshield wipers. For red heat, they just painted the frame and the wipers blue to make the windows look bigger. So that's kind of lazy in my opinion. Now he does have a brand new top, which is supposed to be a ladder, which does have a pretty neat feature because you can flip this part out and make it a lot taller. So he can reach those high buildings. Or I guess reach the waist of a deluxe Autobot. He of course can spin 360 degrees around and another feature it has, you can add one of the blast effects to the tip. So his ladder can convert into a artillery cannon. So that's pretty much it for red heat in fire truck mode. Now we'll take a look at Stakeout. Stakeout of course is a police car and I really like this guy. I think he looks really good. The paint details are fantastic. You got the red and white for the lights up top. Cybertronian writing for what I'm going to assume says police. Autobot symbol there on the front. So right there he's better than red heat who doesn't even get one. Good painted windows all the way around including the back glass. I like this guy. He's really cool. He's got rolling wheels. He rolls. He actually rolls really well. So that's it for Stakeout in vehicle mode. Now for comparison here's the siege rescue patrol with their generation one counterparts. Now in G1 red heat was named red hot. But I guess Frank decided not to let Hasbro use his name anymore. And here's the rest of the G1 rescue patrol. Seawatch and fix it. Now moving on to transformation we'll go ahead and do red heat first. He transforms just like top shot. We're going to take the ladder flip around so we can flip the front forward which brings up those little white sections and flip all the way around forming the feet and legs. Bring these white sections back. Those will make heel spurs.   There is red heat in robot mode. Lot of nice molded details. I love the looks on him. But he is the exact same as top shot. I mean same molded details and everything. He does have a slightly different head sculpt as you can see. Of course much more painted details on top shot. So I don't know why they didn't like red heat the same as they did top shot. They just kind of went lazy with him. Articulation arms can do a complete 360. His legs can move. His waist can swivel and he has a knee bend. But mine has some awful loose legs. I mean they're not, I mean they're, that's bad. I have a really hard time standing him up. So I kind of, what I've had to do to display is bring the ladder down a little bit and give him his third leg. Yeah that was juvenile. So now let's move on to stake out. Stake out has a very simple transformation. Flip the back around and pop off both legs. This is something I was going to mention. His legs pop off so easy. Normally I would edit stuff out but I'm all about the humor this morning. I got no legs. There we go. So once you have the legs reattached take the front bend over the back and pull the arms out. And there you have stake out in robot mode. And he looks really good. I love the head sculpt. The face sculpt. I wish they could have gave him a paint advisor but at least his face is a different color than the rest of his head which actually can turn. Barely get a hold of it but the head can turn around. A lot of nice molded details on the front, articulation, legs up and down all around. He does have a knee bend thanks to some ball joints and arms can do a complete 360. They're on ball joints as well. I like his robot mode. The only fault really I have with him is that leg popping off issue. Now at first I thought he was a re-collar of road handler but there are no similarities between the two. So stake out is a completely different mold. So there you have it. There is red heat and stake out in robot mode. And now for comparison in robot mode here is the siege rescue patrol with their G1 counterparts and the rest of the generation one rescue patrol. Just like the rest of the siege micro masters the rescue patrol has a combined weapon mode and the easiest way to get to that is to start in their vehicle forms first. First vehicle we're going to transform is red heat. Go ahead and rotate this out of the way and flip the front just like you're going to transform him to robot mode. Now once you get the legs out and around you're going to twist at the waist and then put them back along the top. Now actually these white sections will slot in up top. So now you've got him looking like that. We're going to go ahead and turn the ladder back around and that's it for red heat. For stake out we're going to pop this little handle out from underneath, bend the hood up and then on a double hinge it's going to go down. So you've got that look. Take the back of the car and we'll do this ever so gently not to pop those legs apart. Clip those together very fiddly. So there we go. Clip it together and now you're going to take this peg which will go into this hole and supposedly those little tabs are going to line up and there is weapon mode. I believe the package called that a salvage blaster and I'm pretty sure it's named that because it is junk. But here we have poor side swipe demonstrating how this blaster is held due to the ladder underneath. He can only hold it with an outstretched arm. You cannot bend at the elbow. Now at least you can add the blast effects here on the quote barrels of the blaster. So you've got that look going on. But that is a mode I will never utilize. Now I'm going to be honest with you guys. I am very disappointed in this set. Red heat is just a lazy repaint remold of a far superior figure top shot. I mean the mold is the same but the paint applications are just lazy. Stake out. I like him. He's a good robot, good car but man he pops apart nearly every time I transform him. Hasbro could have done a lot better. Of course a little floor polish on those ball joints and he'll be good to go. They just haven't impressed me at all except for right now I just realized.  So there you go guys. That is war for Cybertron Siege, Rescue Patrol, Red Heat and Stakeout. So does the Siege Micro Master Rescue Patrol belong in your collection?  Other than that these guys are an easy pass. Red Heat, he is a lazy repaint of a much better figure with the Battle Patrol's top shot. I mean I just, he doesn't do it for me. He just, he doesn't even really look that much like a fire truck. Grand is supposed to be Cybertronian. He's just got too much of that top shot in him. Stakeout is a decent looking robot, a really good looking car but I'm not a big fan of his Lieutenant Dan action feature. And I really don't see the sense in paying full price just for one figure plus I can't even hold on to him. So yeah you see these guys on the shelf they're an easy pass. I'd save that money towards a deluxe, a voyager or possibly one of the better figures coming out this summer. And guys I want to thank you for stopping by and checking out my video. Don't forget to like and don't forget to subscribe. And don't forget to hit that bell icon to get notified when I upload new videos. I try to upload one to two times a week just depends on my schedule. Also, check out my new series, The Sit Rep where I sit down with other transformer collectors and we just discuss Transformers. I've had some pretty good episodes and some pretty big names including Bert the Stormtrooper, the Collector 75 and Mike Case. Guys, this is Patriot Pride, signing out. Ho-wah! Hey I really appreciate you guys stopping by my channel. Don't forget to like and don't forget to subscribe. Also check out some of my other videos that I've done on Generation 1 Transformers, Modern Era Transformers and Toy Hacks Repro Label 6. Once again, this is Patriot Pride. Ho-wah!


It's a Oh Welcome to the first video of 20 21 which fingers crossed Should be better. So what are we doing today the first video of 2021 and the first one of I think three today I think yeah, should be three. I think it's three. So the FD of your welcome So before we get into the mean bones of today's video I want to check out the channel in 2020 what happened because to me It's a complete blur. I would've been stuck in this room for a whole year and Just be making videos and nothing much changed So there is this little app that allows to condense your channel into bite-sized chunks Like what was your most popular videos? Engagement all that y'all so this is the first time that I'm gonna see it and I'm looking for it Here we go the gaming beaver. That's me. That's me sound is on should sound be on all right Let's click start 2020. I don't even know how the year was for the channel. It was good, right? First let's go back to January 1st at 2.5. Oh, we got half a million subscribers Hey, no bad. Well top three old Jurassic World evolution. There's no surprise there Oh the Minecraft the Minecraft and was my number one video of this year No way. Oh, that's crazy part three as well. Okay, our subscribers get we get whoa Okay, this I didn't know we gained more views and our uploads were down. Oh my god Oh, I need to break this down. So we got 440,000 subs 2 billion and what a year that there you go Beautiful how was that? Okay, let's let's turn this down music off. It's awful Let's look at these top three videos. So dross world evolution modded now I think a lot of people I mean, it's the only thing I can kind of really do in dross world evolution is Is mods because they're cool. They add something different to the game and apart from that, I've pretty much done everything So actually that number three spot should go to the community of dross world evolution for making amazing models And coding it and adding new things in so that's and I guess we're just dross world evolution the base Uh, the second spot Minecraft When when I started 2020, uh, I was like, oh the COVID happened. I was like, oh, no This is this is gonna be bad, man. This is gonna be really bad But we had so many things sort of like come out of nowhere Um the the minecraft dross world minecraft was one of them. This is episode five I love it. I love it used to see like a part one is do really well Uh on youtube channels, but that's a part five. I am only gonna say that's probably done really well Probably because of the thumbnail. I mean it's gotten dominus rex in there into a raptor the drass world It's got everything you want. It doesn't matter how it was going to mean it And number one That that kind of amazes me that the aisle Two million views if you'd ask me what was my most popular video in 2020 I've definitely wouldn't have said an aisle because they they do well But they don't like perform the most amazement. Maybe they do maybe maybe I should be making more aisle videos But that is exactly what today's video is about because we're gonna jump in to Uh something quite special when it comes to the aisle Uh it came across a while ago and I saved it just for like a video like this and before we do that Let's have a look at this. So we gained from 2019 we gained 70 extra subscribers 38 percent more views 352 million all But we uploaded 30 less How that is crazy You think, you know, we we upload 30 last we'd see 30 percent less views, but we see even more I can only think that that's to do with the quarantine You know more people are watching uh videos and maybe just discovering my old, you know cabalong that I've got So I only made 228 videos. Look at that. Last year was 325 out of a 360 day year It's almost a video every day.  You have to do it all yourself Especially I I my own editor and everything like that So everything I do is is me and it takes such a long time and I I wanted more time for other things in my life Uh, so I'm sorry. No offense How was your end in the year? So we got 3 million Did it can we get confetti and cheers here? There we go But this only shows so much what I want to do is have a quick rundown of the entire channel So the first video of 2020 was uh, Jurassic World evolution video Uh, it was the last DLC. I think we ever got um, which was the Jurassic Park DLC and that was episode 3 I that feels like so long ago And I was like still playing the out and then mods happened in january January 17 mods happened and that's when we got the allosaurus and stuff Hungry shark released a new shark primal carnage like started coming back as well And there it is the mystery of the japanese sonic statue that was uploaded in february I I'm so glad that I did that final trip to japan I was like I'd only been that year in the summer and I was like, I want to go back so badly And then when I found out about this sonic statue in the in the mountains in japan I was like I have to that's a that's more than excuse.  Oh, oh, we got the drastic park pimple machine Yes, I got that that was a good purchase before the quarantine Catching up on funny montages because finally I managed to do it. Oh, yeah We got a shield wall. That was a fun one to do And this this right here manager Like it was at this point when I was I was you know quarantine had proper started kicking at this point And I was like, oh, oh, okay. What can I do like what what is that? What is that to come out and then manita came out of nowhere and I was like, yes Finally something new So I'm so happy that I managed to like manita was released at it really filled in my time Reacting to my deadline series best series on youtube. Oh, look. What am I there it is This was on july when I thought my addiction was getting bad Little did I know it was about to get so much worse More mods. Oh, and I started getting back into um into depth I really started living and then I was distracted because in august Which feels like ages ago, but it really wasn't minecraft dinosaurs or sort of minecraft drastic world came out another one it felt like I was like, I don't know I needed something like a game or something and we had manita and that quickly dropped because like we completed it So quickly. Oh, what's what's next and then out of nowhere as if descended by the given to the from me by the gods We have Jurassic world minecraft came like and I was like, oh, okay. I'll do this then That really helped my god. And then of course we're little nightmares to react to that trailer camcretaceous I think 2020 um could have been a lot worse for me because of All of these like random gems that just for me appeared out of nowhere like manita was like float about But the Jurassic world minecraft came out of nowhere and then camcretaceous like oh, yeah, we're this year now There you go camcretaceous now. Wow. And then we're up to current day. Oh, of course among us I played that a little bit. That was loads of fun. I wish I'd made more on it But uh, everyone was like, oh, we've already played us. Okay I guess I don't play it anymore second extinction as well. That was another one that feels like so long ago It was only october That's crazy Oh, and then I finally caught up with the funny montages at this point everybody had been You know, sort of isolating for so long that they just wanted these party games among us Phasmophobia and let's not forget Fall guys, which actually 2020 was the first year that I started kind of regularly Uh doing live streams and fall guys was one of what like was the main thing the main reason why I did that We did a lot. We really did a lot more than I thought More because I couldn't go out and do other content Um, I'm just so glad that I got that sonic statue done And it was something different because I noticed when this quarantine happened that my videos that I'd done You know a soccer aquarium or anything that was you know swimming with basking sharks anything that was outside Everybody was like, oh, I want to watch this and their views just went up and I was I'm glad that you know I'm not just a let's play channel. I'm more like Anything I want to do whether it gets views or not at some point in my life I'm gonna look back.  It's like it's like a photo album except for a channel and I can just go back and see Uh, all the things that I did and I feel like I've only done this channel for what four years six years now for six years and I feel like we've come so far we've done so many things and You know without the support of you guys watching and enjoying and sharing in our dinosaur nerdy hobby together Uh, we wouldn't have been able to do all these crazy things How about now we do some this like I watched like two seconds of this and I was like, nah This has to be a video. This has to be a video. It has to so this is from a swiss hasaurus Um, and I clicked on it and I just love the like to dislike ratio So first off, I just want to say don't go and give this guy hate. It was obviously a joke Um, the more malicious people that do this kind of thing Don't upload videos about it and even says like oh, who should I impersonate next what I'm curious about this guy went on a server And tried to convince convince sorry another streamer Uh, who goes by simo that he was me every now and again I get comments on discord of people message me saying oh, there's a there's a Uh an imposter in the aisle.  I go no if you could join our discord You can see what I what I'm doing if I'm playing a game or anything as it shows on there So if you see someone who's pretending to be me and it doesn't show me on the discord It's not me for a start. Anyway, because there any mannerisms that he does Oh, this is gonna be interesting. Okay, let's watch Yo, what is going on guys in today's video? We are going to be doing something. I haven't really done yet I have never really done a prank like this tyrannical simo We're gonna be pranking him that we are the youtuber the famous the popular the gaming beaver I'm going to be doing this in a very strategic way and uh Try to trick him the best I can and the rest of the server and it let me tell you it works out pretty That's the main reason I want to know what he does like I've even in the last aisle video. It's someone who was Just so sure that I was an imposter to the point where he was hurling abuse at me It's got to this stage where some people like nah, it's never the real people So what what did he do? Just want to give a huge thanks so quick to all the admins over on the bioile for helping me and playing along with this Especially ant man You're welcome the owner of the bioile link in the description for their discord And link in the description for beaver's youtube channel. Of course, you probably already know it, but wait, did he did he actually credit? Did he did he link my youtube channel? He did as well. It's a boy. It's a public fold Nice, I see you So first thing I gotta do is I gotta change my name to the gaming beaver, of course And then I have to completely replicate his profile Oh, okay. How'd you do this better do it? So Let's change my name and let's find an accurate profile picture for be okay for a start For a start when you change your username It like steam does tell you what they've also went by so what they've changed it to and I think mines only ever been like too It's like a game beaver or the game beaver So that's that's another way to tell I think if you can even like view profiles on that on I scoured the internet for his correct profile picture that matches his steam and um I'm kind of stupid because he was right in front of me the whole time I I was gonna say you just go on just go on the profile picture now I have no idea my profile is private just outline the screenshot And boom save it And now we're gonna put it as my steam profile picture. All right, so we got the picture uploaded And yeah cheeky buggy Okay, this looks so can you not find that picture in your own? So let's save the changes And let's uh, let's put up the game when I start my youtube channel six years ago I had no idea that this was gonna be a thing. This is so cool beaver. He's in a way for six years now Very long time. I'm a A veteran of his channel. I guess you can say but it's You know to see people's reaction Um to him being on the game James or the gaming beaver. He's never really like Grown yes, he doesn't really understand. I'll play the game. He doesn't have So basically we're gonna impersonate him.  So it's gonna be something new Interesting Interest I wonder if I was being a serato at this point. Okay, if I'd never made a video make it seem like I am beaver So this are it come on this already like other than my steam id I doubt they're gonna go looking for a steam id because that's very difficult to go through all of his videos I was looking for a steam id but come on. That's what I should do I should start every album video like this is my steam id. There you go done Look how Legit that looks like seriously I've noticed a beaver doesn't really talk in global that all like he doesn't really talk in global that much unless I need nests My goal is to find more seratos or something near me that I can talk to To sort of nudge people and like oh wait, is that beaver? I just I hope there's more seratos That way I can talk in local and then because that's usually how beaver like talks to people You'll find them the final the species doesn't really care about global who find out the species. He'll talk to them in Local beaver beaver doesn't have a lot of time to play this game So he doesn't really know like what he can actually match up against he kind of likes to run from things Trying to shame them or anything. I'm just pointing out their behaviors It's not wrong. It's not wrong. He's gonna go.   I always end up dying anyway. Oh my god, it's Um If I said yes, you wouldn't believe me and not worded correctly, but I would with the same kind of Example I would be like if I was would you believe me not like you wouldn't believe me like He says if I said yes, you wouldn't believe me Oh my god, this is brilliant. Okay. Okay. They believe us. They believe us. Oh my gosh Because I'm usually concentrating. I don't get to spend this much time looking at chat.  That's why you died instantly. Okay, but someone's reaction is priceless So I've never actually played with simo. I think we both played I was watching him stream once When over my first came out, but apart from that, I've never I never came across the guy Oh, look even he think he's skeptical. Okay. Okay. All right. So no suspicions yet. This this video is Sounds everywhere.  I would be too. So he's still skeptical. Now. How does he convince him though? This is the interesting thing. Thank you. I think I'm following him. I wouldn't even need I would be like I wouldn't even care. I would be like, well, it'll be in the video, right? So Whether he believes me or not, I wouldn't want I wouldn't even want to convince him I just feel like let's let's play and have some fun. But if he does, I want to see how he does it It's just like a normal aisle video when I think it's me. I get eaten Where you're the real Cool. I guys we have them fooled. I don't know. I don't know how much more confirmation we can get. We literally have them fooled Well, I guess okay, let's do this Wait a minute. He became a friggin adult Well, we just fast forward like five hours or something.      We were um, our goal was to go to twins So I was like, you know what? I don't really want to walk all the way to twins So I DM'd amp and I'm like, yo, can you spawn as like a gig or something and murder me on the beach?  Okay Like button that'd be awesome. I worked really hard to get this video out and edited this and all that fun stuff So I would really like it if it could send me blow up and kind of just get big in the community So you can help me Humble I see. Uh, yeah, I spent ages on this video Be really hard to me if you could just like it and share it so it could blow up that'd be great Don't buy like in the video. That'd be awesome. Also, if you made it this far Uh, comment down below which content creator I should do next You can do any like big content impersonate yourself That's over like a thousand subs. Wait, wait. Do you have a thousand subs that way? He doesn't have a thousand subs bollocks Do we get him over a thousand subs guys get give him a thousand subs I want to impersonate himself. Did he ever impersonate anybody else? No. Oh, well there you have it That was that was it.  So I apologize for for that Not the really much I could do though. Really. Oh look. He's even got like the same thumb Like sorry title life of a sub adult rex. There we go to ended don't send hage to this guy He seems to have stopped it and anyway, it was all for a joke But that was just a harmless little joke and I I think it was good. It was good. And I got a video out of it. Yes Anyway guys, if you enjoyed this video, I'd like hopefully 2021 is much better to you and me than 2020 was and we can restore some sort of normality And I will of course get back to doing what I do. I'm gonna keep on beavering away making my content Anyway guys if you enjoyed the video leave a like and until next time I'll see you later as an imposter. Bye


Hello, I'm Dailey Pearson, I'm a co-founder at Ludo. I went to Griffith Film School, and now I'm executive producing Bluey and Robbie Hood and a bunch of really beautiful shows here at Ludo. And we'd love to meet you. So reach out to us at Ludo. We love having coffee with our cool new people. So if you're not cool. Yeah, Bluey's super, super popular in our family. So being able to work on this is a big deal for my kids and me for me too. But it's a really special thing, being able to say to them when these episodes come out.  I think they'll be really excited about it. Before there was not a lot of opportunities in Brisbane, especially, but Ludo's really opened that up. Bluey's such a big influence to so many young kids in Australia. So having that opportunity to work with a studio like this, it's amazing. People only really want to help people who are helping themselves. And I think that's such a really valuable lesson for me to learn and that you can't go in like a lot of a twist with your hands out. You need to help yourself and people. Do want to help people who are helping themselves. It is very challenging juggling family life and work life and university. It's not impossible, but it does require a lot of sacrifices and give and take from so many people. But I think it does make that a bit easier. There's a lot of support for that. And I think I've been able to pull it off because I'm still here and I'm alive. Recently, the opportunities just opened up a lot and it's just, yeah, animation's an amazing place right now to be in.


So, let's pass now the floor to Jordi. So... Okay. Thank you for inviting me to this meeting. I will talk from a different perspective, let's say, because I am managing, co-managing an archive of human data, genomic human data, and I'm not a lawyer and not an expert on all these ethical and legal issues. I'm more a technical guy and a biological guy that is trying to run a service and make it useful for the users, okay? So this service, it's called the EGA, you see the logo up, sorry. You see the logo, I think, up there, and it's co-run by the CRG and the MDL EBI, this is the European Bioinformatics Institute and the Center for Genomic Regulation. This name in the legal context, when I'm sometimes speaking, is a little bit misleading. We are not talking about regulations in the term of laws. We are talking about regulation in the biological sense, okay? What opens or switches off the given genes in our bodies, in our cells, in different times in our lives, okay? So it's the kind of regulation we are talking about. We are a center that is involved in all kinds of genomic research, and especially we have this co-managing this archive, okay? These are our funders. One of the things that we are very grateful is to the BSC, the BSC is where we are having hosting everything, so and they are also hosting, I think, the RDA meeting today or so. So it's our own partner too, although it's not exactly running the service, okay? So data sharing is wonderful, as we all know by now, I think, and in the terms of the genomic world, it has started to happen that people start to do sequencing, initially from bacteria and these kinds of organisms, and very, very soon they started to sequence a human data, meaning some specific genes, for example, to detect some specific disease, understand better diseases, and other people is also sequencing, and they see clearly that just sequencing a few people is not enough for getting some biological conclusions. So they thought, if we can increase the sample number, this would be very wonderful, because sequencing is very expensive, so if we can share everything, then we can have better samples, bigger samples, and we will reuse money, and everyone says it's a good idea, the funders say this is a good idea, so let's do it. So let's put this data somewhere that we could just use it, okay? So we decided to share and so on. But because this is human data, this is sensible data, and very soon some people said, come on, this data is very sensible, and it's my genome, it's myself, let's say, if you want. So call you there to share this data without my consent, or without me knowing that you are doing this, okay? So the big archive at that time are just, as I said, hosting bacteria data, or animal data, or plant data, and they start to have some human data decide that something needs to be done, and the first solution was, let's put this data in a jail, okay? I never know if putting here a jail or putting a kind of political or king or someone that needs to be protected from the crowds, okay? Because sometimes it looks like the data is culprit or something is guilty and needs to be hidden because it's a bad thing, and sometimes it's just the opposite, this data is wonderful and needs to be protected because it's the best thing in the world. So we put in sometimes police who is actually this data, are you always to go to this data or not? We put some lawyers on it, who you will use this data, which are the conditions for using it, and which has the legal terms for doing that, and we also put some kind of body words to saying what you are doing to this data is good or is bad. So you can approach this guy to get an autograph, something like that, the signature, and we are looking at you that you are not doing anything bad to this thing, okay? So this is the first approach for all human genomic or genetic data that we start to share. Let's put everything in control and be sure that nothing bad happens to this information. This is relevant in the sense that this is your identity if you want, okay? If you look at these forensic films or TV movies, they are detecting the killers and the culprits of all the stuff by looking at the DNA in many different places, in the bottles and in the handkerchief and everywhere, okay? So they could determine if a person has been there in some point in time given their DNA. So having access to these could tell you many things about this person. The ethnicity, the kind of diseases it can have, indeed the pronostic of their life if you want, so you can have very relevant information about this person looking at their DNA, okay? So it's quite sensitive, not just yours.  So it's kind of delicate ethical stuff, okay? So that's the point, that we need to do something. So the EBI that has one of the biggest nucleotide or genomic archive in the world decided to put some things under control and they created the EGA. The EGA was created, the European Genome and Phenomarchive was created in 2008, and in 2013 the CRG has joined this effort in order to do both joint efforts to do this. What we do is we get information, genomic information from studies, research studies, usually clinical studies, and we store this thing in our secure archive, in long-term archive, so it's there for tens of years probably. And then we asked the people that is the owner of this data to set up what we call the data access committee, that this is two things here, for example, and with this data access committee when a user wants, the user here wants to access the data, we redirect them to the relevant data access committee, if you are interested in a given study or in another study, these people throw some tools, provide access to the users to the EGA, okay? So then we create the personal and user accounts and bring this information to the user and this, they could access all this information that it's under control access, okay? What this means then is that the data owners does a submission sending the data to us and the metadata to us also as possible with ontologies and so on, and then we provide them a set of tools to control who is accessing this information and also the tools for the end users to get this information, currently mainly downloading this information to their own premises and they are starting their own analysis, okay? So this is the, let's say the life cycle of the EGA, yeah? I hope this is clear enough. So we see that this is a kind of bureaucratic stuff, meaning that for everything that you want to access, you need to apply, you need to send letters or mails or whatever and sign documents and have commitments that you will use this data for the good and so on, and sometimes you are getting very big amount of data. This genomic data is big, okay? Currently the EGA is about four petabytes, just one copy of the EGA is when you have three, okay? It's four petabytes, this means 4,000 terabytes. You know if you go to any electronic market thing that you can buy this from one or two terabytes, we are talking about 4,000 or 2,000 disks like that, okay? And three copies of them. So it's a big information, not all the data sets. You don't need all the data sets, but we have some data sets that are about half a petabyte, it's 500 terabytes. So not, I would say, few institutions in the world are able to manage this volume of information, okay? So you need to apply to this, and after, let's say, two months you get access to this information, and then you go there and you realize that the information is not exactly what you want. Because when you sequence people, sometimes you sequence some parts better than others, you have issues, so maybe the thing that you're looking for is not there. So you spent an amount of time applying an amount of money and time and resources, getting the data, opening the data, looking at them to realize that what you're looking for is not there. So people start to say, what if we can share just something? Something that maybe is just showing aggregate data. So summaries of data, anonymized data, but in the sense of making them aggregates, and that's good, okay? So this is safety in the numbers. Quite soon, people, mathematicians, statisticians started to realize that, well, being in numbers is good because you are kind of hiding inside here, but having the right tools, like this guy here, this hook, could allow you to pick one specific personal people, animal in this case, okay? Starling, probably, I don't know, from this flock, and well, if you are the oldest one, you are happy. If you are the one being picket, you are not happy at all. Okay, well, you are nothing else from that point on, okay? Not happy, you are dead, mainly. Okay, so the thing is that this is not enough. This is an example of a paper that starts to look this, not in genomic data, but in proteomic data, meaning that just from your blood, you can get all your proteins in your blood, and from these proteins, we have the level of resolution to start to see what are the specific mutations you have in your proteins that could allow us to identify you between other people, okay? So the thing is not just for genomic data, your DNA, but from others. And indeed, there are now studies that from your macro biome, it means the bacteria that you have in your skin and so on, we can identify if you have been in another room or which is your house in a neighborhood, okay? Just looking at the signature of your bacteria there.  So these kinds of things is starting to happen. And so the level of privacy is less and less is, well, in the country, is more and more blurred, yeah? Okay, so the safety in the numbers I said is not a good solution. So we need to do something else. Well, so we have this sharing dilemma that you already know. Here, we have expressed this dilemma in the sense of we have these data production initiatives or directives, and we also have these openness, a directive that are kind of conflicting. This is the same thing in this genomic area, as I explained it. One is looking for a sample size. The other one is keeping the privacy of the people as much as possible, okay? So this guy is able to handle four horses, not just two, okay? This is a demonstration he did in Canada. This is a French guy, I think, or a Belgian guy, I don't remember right now. And he's able to do with four horses, it's not bad. So I hope that you can do the same with these all legal stuff that we are talking about, okay? So one solution is to create these connected silos. So some institutions has decided to sign contracts between them in order to share data maybe in just the same repository or maybe in distributed repository. So several hospitals, for example, or several academic institutions could agree in sharing this data. But again, this is just for the sake of this small community if you want. So it's not a good solution either. So in one point in time, something called the Global Alliance Has Born is I think it's 2013 towards 2014. This is a community of all the biomedical research and centers that are working in genomics data in order to see how we can do to better share, to harmonize what we are sharing and to foster the reuse of the data, okay? The Global Alliance has several stuff, I will go faster on it, but it's looking in both aspects. The technical aspect and which are the formats, which are the anthologies, we are the APIs that we can share. The API is the programmatic interfaces that we can share and the web services, let's say. And also all the ethical and security stuff related to this. So there are initiatives in the, this is a global level, there are something in Europe that it's called Elixir. Elixir is both looking at this kind of stuff, but also at the infrastructure. So where we put the data, which are the clouds we can use, which are the network communications and blah, blah, blah. Okay, so it's a broader thing. This is just two half standards. The other thing is to have standards and infrastructure. So it's a little bit more, it's broader, let's say. In the context of the Global Alliance, we started to work in two different models for sharing data and describing the data use consent. This morning, I had to left this morning for a meeting, but in the first session, we said that the consent is a very relevant thing. And this community is working on that because this is one of our issues, okay? One of the issues is that we need to share this data as much as possible, as I said, because it's expensive in many different senses and it's very valuable in other senses, okay? So we face the thing that in some cases, yesterday, for example, I get a request from a researcher here in Barcelona that tell me our consent for our patients, the donors that have given us their DNA says that we can only use this data in the context of alcohol abuse that was the context of this study, okay? So we can only reuse this data if the study that wants to use the data is related to alcohol abuse, not just drug abuse or addictions in general or something like that. If it's not related to alcohol abuse, we cannot use this data. This, of course, is very bad because we cannot reuse this for other stuff like using these people as controls, like people not having cancer or any other kind of stuff that is very useful, okay? So this is the kind of things that we are trying to do. This, again, is writing in papers and in documents, and we are trying to classify different rules that are quite common in the consent in order to allow both the requester and the data owner to describe their consent to share and their consent to reuse. So we can match them, and although it's not fully automatic, what we will try to do is to provide the data access committee an interface that is saying, okay, everything looks matched, the your data consent and the request or the proposed of the study of the requester, everything needs to match, you just need to say, okay, and it's on, okay? Or so you don't need to read all the documents and so on. This is one model that it's simple. It's kind of 20 different categories. Some of them are mandatory, other ones are optional, but there is another initiative that it's called Adam, that it's much more detailed, much more granular, and it's much more oriented to be fully machine readable, okay? So the idea is to describe everything in a format that a machine could read, and if possible, could take decisions. For example, if this says this is open to everything, then you don't need to check anything, okay? It says it's just for general research that it's something that is quite common, hopefully, or luckily, then it's not much more than that. If it starts to say it's only usable in this ethnicity or in this geographic context, then you need to look a little bit forward, okay? But well, I think it's an interesting step. And similar to the data tax that Peter has shown us, we have started with three different layers of access. The first one is fully open or public, that we said it's also green. The other one is to register it. This means that we are trying to share some aggregate data just for people that we know their identity, okay? And in this context, we are trying, or the LXE in this case is trying to define what they call the bona fide researcher, meaning that if you, for example, has had any paper published, or we can check that you have an institutional account in an academic place or something like that and you are not administrative staff or these kinds of things, then we will give you automatic access to some data that it's not sensible, let's say, or not sensible enough in order to identify yourself. And then we have the more restrictive level that it's the control access, one that's in red that asks you for applying to this thing probably signing some papers or your institution signing some papers and getting some commitments and so on, okay? So in this context, we are working in all this stuff. They're trying to make data useful. I haven't talked about making the code to the data. It's something that I haven't thought for this talk, but it's another thing, okay? As I said before, our data is quite big. The resources for analyzing this data is quite demanding. So what we are trying to do is allow people to do the analysis close to the data. This is nice, but this means that the burden of paying for the resources for doing the computing and so on should be sustained by our institutions and this is another story and it's not easy to solve, of course, okay? Because we are talking about very, very big computers, okay? And it's not laptop or something like that. It's computers that are hundreds of processors, no, thousands of processors, hundreds of RAM memory, big disks and so on. So it's a very expensive machine that you need to process this kind of thing, okay? So these are my teammates. This is a little bit updated, but these are my teammates in both teams, AI and CRG and these are our funders. You can see plenty of them, okay? Thank you and we are open for questions, I think. Thank you, Giorgio. I think with this third presentation, we're pretty much close to a cycle where we've seen different ways in which you can actually solve the question of how you minimize the transaction costs in an economic sense, transaction costs when you try to access data. And every time, and I think actually this is one of the primary objectives of the European Union policies with regards to what is now called the European Open Science Clouds, also what is called the European Cloud Initiative, actually how you combine all these little elements of the infrastructure in order to minimize transaction costs. However, before I give the floor to the audience, I'm always whenever we go through these discussions, I always think the old saying of the science fiction author T Clarke that the answer to the machine is in the machine. But I'm really curious, we're doing all these 10 rounds and we're trying to find technical solutions for basically a legal problem. And some of these solutions require as we see extensive, really extensive development and work to develop tagging schemes or workflows and expression, technical semantic expressions of licenses or access protocols and facilities. So how much do you think this is viable as, keep doing like other than us finding each other in these lovely places. But other than that, what is the benefit of actually going for technical solutions for essentially a legal problem? Well, I saw some similarities but also some differences. And I will focus on the, let us say the text and data mining similarity and difference between Stalios and me and on the data tagging versus the levels of access with Jordi. And well, I think there is also a different starting point mainly between Stalios and me because we even do not have this. Well, I mentioned it as an example that there is this private digital library of this 160,000 works which is on the computer, probably he has backed it up and so on, of this person. And he may not even give it to us so we cannot even yet begin to make it accessible although the approach would seem very interesting. We have so far looked into the material, well in the metadata of the material and indeed it is a jungle of copyrights that apply there and I really would be, I would be so grateful if there would be a possibility to harmonize or to standardize that but I'm also afraid that that will be really, really very, very hard. And that is why we thought let us try to in this, in the kind of permissive society that the Netherlands still is similar to the use of soft drugs to get at least the permission or have the publishers tolerate that in a protected environment researchers can start using that body of knowledge. And then, so I'm not sure that the technological solution will certainly be not the only thing. You need to do certainly something in advance. And then with respect to the layers of access, I indeed think that is a very important idea or not idea, also practice, it has been a practice already for some time but it is still as far as I know actually not really solved how many levels of access you would need. The Harvard example gives what is it six or seven levels but to be honest, we are not entirely sure whether that would apply because for instance privacy legislation actually says only you can have access or you cannot. And to try and get those different levels will be a bit of how should I say interpretation but that is also not very different from the situation today where I see under the same copyright legislations there are existing very different interpretations. For instance our central Bureau of Statistics is very, very strict and the social and cultural planning office and the two are often working together, they are even collecting the same kind of data. They are much more liberal, you know, and this only says there is more to it than just the law and there is also more to it than just technological solutions. I'll pass it to Stella just to say two things on what you said which are important, clarifications, I think the access layers very much relate to consent. So personal data are black, white, but consent is not and I think, and we know that from work of other groups, Oxford has done a lot of work on this issue and Shulet Packard has done a lot of work on consent management and that's an interesting thing to combine these research one day. With regards to the question of statistics, offices and cultural institutions, again these are separate legal regimes on the top of copyrights and we have great fragmentation in Europe and we've seen that with Stelios also in the context of PSI. There are sub legal regimes within the context of public information and it's a nightmare. Stelios, about the tags as well, you also had the laundry tags. Just very quickly, first of all, let me tell you that it is a very interesting linguistic but also a computing problem to try and see how one can bridge the inherent feature of language which is to be variant. There are many different ways to express the same thing and this is what we call language variation and we observe it in many legal statements. We observe it in many legal documents. People essentially say the same thing, mean the same thing, but they use different words. So what one has to do is when analyzing the documents try to get, if you want, the logical form of each and every legal document and if the logical form is identical then the two documents are identical or depending on any sort of ontology that you may have the documents can be made interoperable or can be decided as being interoperable. So it is a very interesting research question. I fully agree with Peter and with Pro. It will not be just technology that will solve the problem or just the law that will solve the problem. Of course, the law would really do us real favor. Yes, absolutely, if some of the problems were retracted. Just one comment. Technology is evolving at imaginative speeds. Recently, rather not recently, it's a couple of years ago, we managed to package engines, sheet the engines to the Sanders library and extract from the Sanders data some of some information without moving the data set from its original place. So things can be done. There are many different things, many different solutions. In Open Minded, actually what we're developing is a solution where you have a workflow that performs certain tasks, you can package it in what we call a docker image and you can dispatch the docker image or you can download the docker image and use it on your personal machine. Now the degree to which these solutions will work accurately is, still needs to be proved, tested and proved, and the degree to which these solutions will be taken out also needs to be tested. So I will cite Groucho Marx here.  So I will say technology is not all. That was very Marxist of you. So the technology will not solve all, but I think that will help very, very much. For example, in our case, we are happy in the sense or lucky in the sense that we are not dealing with thousands and hundreds or millions of documents, we are talking about thousands of studies and so we can manage more or less that the concerns are similar and the problematic is similar, the scope is similar, so we can kind of classify things and so on. But we face the other aspect that the people that should look into this, it's various cars. So I, for example, was approached by one oncologist, a very relevant oncologist here in Barcelona and this gentleman is leading a couple of studies on leukemia and he said, well, I had an ethical committee in my institution but when they approached them saying, okay, will you help me in seeing if these applicants matches the consent that they have from my patients. The ethical committee says, okay, we will see the general one but from here on, you will need to manage yourself. So now I have a very relevant medical doctor with a very talent on this oncology thing that needs to look at legal statements trying to understand if the request is matching their consent or not.  So I don't want this gentleman and any other similar gentleman or lady in the world doing this stuff. I want them to be as fast as possible opening the data and being sure that they will not be sued because they have opened something that shouldn't. So in this case, I hope that technology is helping him to get both things. There's confidence and the speed to do this thing. And I think that in terms of these much more diverse terms and copyrights and so on, we should also help because then the nightmare is the opposite. You don't have too much variability although you can have much more time to look into this maybe. So I'm a fan of technology for this thing. I think it's time to pass the floor to you. So any pressing questions? Now that you have the opportunity we have them trapped here. Okay. I see the problem with all these concepts. These things we are also about to handle and we're trying to handle. And I think it's rather complicated especially if you're going on a European level because you have very different understanding of ethics and you have very different constructs of ethics committees. And as long as you stick to a certain country, I think it's possible to try to harmonize in a way all these limitations you can have in a constant. As soon as you come to an international level I think it would be almost impossible. We have this problem in Germany because we have different states and different states have different legislation in regard to health. So we already have this problem within Germany. So I don't think that's really a solution. It's a lot of work and it's really it's really all my respect to your concept for these different ways of coding these concepts. But in my opinion this cannot be the way to reflect any and every speciality in limitations. Shouldn't we have a way to come over that in some way? Well, these codes come not just from the Spanish or the UK experience. We look at all the consents that we have that we ask at our users, not a lot of them give it to us, but we look at different of them and we are talking on projects coming from Australia, from Japan, from China, from I would say almost every country in the world except Africa that is just going into the wagon. They share a very big interesting bunch of common stuff. I will not say that people is copying the consents one from another, but it's happening more and more. So I think that we have this common ground and the idea is that if we cannot fully automatize this thing and I think it could be difficult, but at least to facilitate as much as possible the thing.  If the person is consenting to this thing then we are fine. We are talking about research that are more than not electronic health records and this kind of thing that is another kind of beast. But for this the community is also working on that and see how we can make electronic health records part of them at least, anonymized at some extent or the maximum extent that it makes sense to do this. I would say that it's easier to do this with electronic health record because it's not as identifiable as the genome is, the DNA is. I concur that you can know many things about people looking not just at electronic health records. We said how much you are tweeting and from how much you are tweeting and so on maybe you can detect which person is in the Twitter cloud. But probably if you share the same kind of people in these numbers probably you are more safe in the case of DNA. So our experience is that although the laws are there these consents are like I will not say well are on top of this thing. We have any other questions? I think you have been very intimidating to the audience. They see your wisdom and they feel that they cannot really ask. It's only two minutes that actually separate us from our lunch. I think it would be very risky of me to actually stand between the lunch and the audience. I would like to ask all of us to join our hands and thank our speakers. I will hand them when they try to have lunch and ask questions in private. Thank you.


The 15th Region Baseball Tournament pairings were drawn today at Shelby Valley High School. Each district champion chose their faked from each district runner-up. Taking a look at tomorrow's schedule, the 58th district champions for the first time in five years, the Allen Central Rebels will meet up with Shelby Valley starting at 10 a.m. Our first match with Shelby Valley we've already faced in one time this year. They're a good, solid ball club so we're going to have to bring our game. Being the home team, that does help. In game two, the 57th district champions, the Johnson Central Golden Eagles, will pair up with Pike Central at 1 p.m. and then following the defending 15th Region champions, the Lawrence County Bulldogs will pair up with Prestonsburg as they face off at 4 p.m. We always come in trying to, you know, plan to win it, you know, when possible. This year's no different than any other year. Stuff's drawn up. All like this, when it gets down to the end of the season, you're going to have to play everybody eventually. We'll play the winner so it's just time for the boys to start playing by. In the nightcap on the baseball diamond tomorrow at 7 p.m., the 59th district champions, the Pikeville Panthers, will match up with Sheldon Clark. Well anytime we get to the regional tournament, our goal is to win it and go back to the state. Finish the season at 23 and 11, we feel like we've got a good shot and we expect to do well. Once again, the region tournament gets underway beginning at 10 a.m. at the Johnson Brothers Athletics Complex at Shelby Valley High School. Reporting in Pikeville for EKB News, I'm McKayla Colley.