The broadcast is now starting. All attendees are in listen-only mode. Good morning traders. Can everybody hear me and see my screen? If you could just type yes in the questions there. Alright excellent. Okay, thanks guys. Okay, so well, thanks for coming. This is part of the book map professional trader webinar series here and today we have Brett Steenbarger here. If you don't know him or haven't read some of his books, I would recommend it. I've read two or three of his books, I believe here. He is a trader, a psychologist, trading a trader as well and an author of several books here as you guys can see. So, he has an interest in using historical patterns in the markets to finding an edge and is a performance coach for portfolio managers and traders at financial institutions. So, we're very pleased to have him here and I'll let Brett take it away. Before that, let me just go through the risk disclaimer, trading futures, equities and digital currencies involves substantial risk of loss and is not suitable for all investors. Past performance is not necessarily indicative of future results. Okay, well, thank you very much, Brett and take it away. Okay, well, thank you very much, Bruce. I appreciate the opportunity to be here with everyone and talk about the topic of evaluating our trading and improving ourselves as traders. So, we have a few slides. We'll go through some material, but we will have plenty of time for questions and answers as we go forward. I appreciate, Bruce, you doing the forwarding of the slides. My hands are tied up. I'm doing this from home and there is a crying cat on my lap who will not leave. So, my hands are rather tied up. Anyway, you can see my name and then the URL for trader feed by blog. And so, when we talk about topics today, if you Google Trader Feed and then the name of the topic, you will likely find a search for a number of different blog posts. So, it's a great way of reading up on specific trading psychology topics. There are well over 5,000 posts on Trader Feed. They touch on a wide variety of topics. So, it's a nice resource. If you want to go into greater depth, on a particular topic. Okay. So, before we get to the first slide, let's just talk about why it's so important to evaluate your trading. I have a blog post on this very topic right now. If you were to go to the Trader Feed site, you can see that. We want to stay on a solid learning curve as traders. Our learning is enhanced when we look at specific aspects of our trading and systematically go about improving those. So, we want to not just keep a journal in the sense of writing down what happened during a trading day or trading week. We want to observe specifically, concretely, what we've done well, what we haven't done so well, and what we are going to do, again specifically, what we're going to do going forward, to continue doing what we did well and to improve what we didn't do so well. So, you want each day's trading, each week's trading, to become a tool for learning. The way I've often put it is that any day or any week may or may not be positive in absolute P&L, but you want every day, every week, to be positive in terms of learning P&L. You want to get something out of your trading, even if the trading hasn't made money that particular period of time. So, there are a few ways of becoming more effective in evaluating our trading and moving forward our learning curve that I have learned from successful traders I've worked with and those are the things I would like to share with you today. And then, like I said, we will open it up for questions and for comments. So, let's go to the first slide. Because what we're doing is we're breaking trading down into a few component processes. This is very important. You know, when we talk about trading well, we're not just talking about doing one thing. There are a number of actions that contribute to our success as traders. So, the first one is idea generation, which means coming up with good ideas, ideas that are worth trading. I work with portfolio managers at a variety of different types of hedge funds, macro hedge funds, equity hedge funds, funds with very specialized strategies, fixed income strategies, commodity strategies. So, I've had an opportunity to see what the successful folks differently from the less successful ones. And one striking finding is that the successful traders work with new and different data. In other words, they are not looking at the same things as everyone else. Everyone else is looking at the daily bar chart, is looking at a 200-day moving average. The successful traders I work with are not doing that. They're looking at things that other people literally are not looking at. Now, this is really, really important because by looking at new and relevant important information, they are able to generate new and relevant trading ideas. Now, those of you familiar with Bookmap know that one of the things that Bookmap does is introduce new data, new things to look at. So, you're looking at order flow in real time, but uniquely, you're looking at that order flow in the context of historical order flow. In other words, you're looking at where bids and offers are now in the market, but you're looking at how that compares to where they have been.  That is useful information. In fact, when I started working with traders in Chicago, that depth of market ladder was the new data. No one else was looking at that. Everyone was looking at bar charts, and looking at order flow was new and different, and that's why the traders were so successful trading on short time frames. Now, you look at order flow, but you put it into context. So, you see where buyers and sellers are placing their orders, but you're seeing how that differs from how they've behaved in the recent past, and that gives you some ideas about whether those buyers and sellers are more and less aggressive. Some of you know that I've also worked with something called Market Delta, where you are looking at actual transactions. You're not looking at the bids and offers, you're looking at transactions, and where those occur in the bid offer matrix. So, if a, I don't know, 100,000 share of what is transacted, does that occur nearer to the bid price or nearer to the offer price? When we see transactions nearer to the offer prices, buyers are being more aggressive, nearer to the bid prices, sellers are more aggressive, and over time you look at every single transaction, and what does that tell you? It tells you over time if buyers are becoming more aggressive and sellers are becoming more aggressive. Another thing I look at is the NYSE TICK, the number of upticks versus downticks. I also look at tick measures for the Dow stocks, or NASDAQ stocks. I look at the upticks and downticks for all traded stocks across the listed exchanges. And so that's telling you, is the stock trading on an uptick or downtick, but it's accumulating that over all stocks. That's new information you can see in real time if upticks are dominating or downticks are dominating, or buyers are more aggressive, sellers are more aggressive. That's in real time, and you can see the flows of that information. So much richness of information that you would never, ever get simply by looking at a normal bar chart. So those are examples of working with the new data. Networking is also a way we can improve our idea generation. Well, I mean by networking is connecting with people who themselves are doing unique things, looking at markets in unique ways. When we work closely with others, either on a trading floor, this happens at the teams I work with, at SMB for instance, you have a senior trader leading the team, you have junior traders working with them, but everyone's sharing information, everyone's sharing trades with everyone else. You can see how they're thinking, what they're doing, and you can look at the market through different lenses, which helps you generate ideas. But there are many people who are working online in teams, either with individuals or with some trading groups. The investors underground, the traders for a cause group is one of those. We have groups such as the ones run by modern rock that look at very short-term price action and share trade ideas in real time. And that becomes a way of networking with others, a way of interacting, but also a way of observing what other people are doing and how they're doing it to help us generate new ways of looking at markets. Ultimately what we're doing with new data and with networking is building our creativity. And this is something I talk about in my most recent book, the Trading Psychology 2.0, that markets are always changing. Sometimes they're trending, sometimes they're in a range, sometimes they're moving up, sometimes they're moving down. Recently we've had markets moving down quite a bit and up quite a bit. And so the setups that work are different in different markets. The information that helps us trade effectively will change as markets change. And so we always have to adapt to these market changes. And so when we can look at new data, when we can network with smart people, we build our ability to generate new and different ideas to fit market conditions. And that really is exercising our creativity. The idea of finding an edge and just sticking to that edge through all markets, that is completely false. I don't know any successful trader who actually does that over time. Because markets change, eventually the edges go away and have to be replaced by new ones. And that's where creativity comes in. That's where creativity comes in. Next slide. Okay, so creativity is all about generating the idea, right? But once we have an idea that's worth trading, we have to turn that idea into a trade. And so that's where position comes in. I have found a number of successful traders who will establish their positions based on their ideas, and then they will use the short-term price action to trade around those positions. And I'll explain to you in a minute one way, I do that. But what they're doing is, and this is a term I hear a lot among the SMB traders, is they're creating cash flow in the trade.  And then the market comes in a bit and they might add to their position. And so they're flowing in and out of their positions, even while they hold some core position for the bigger picture move. Now that helps the trader psychologically because in a situation where you're building cash flow, you're making money on these pieces of the position. And let's say some news comes out and the idea doesn't work out and everything reverses and goes back to your entry point, you have harvested some profits. You haven't just made money in the trade and then given it all back. And so psychologically to ring the cash register with some frequency builds an internal sense of success. And the key is making sure that the core position is large enough to matter if it goes to your target and to take enough of the profits that that will matter if your bigger picture position doesn't go to its target. So you want to make your entries large enough so that you have room to take something off if the trade goes your way. And you want to be rule based about that. In other words, you'll have a first target, you'll have a second target. So for instance, if I identify a price level, I think a near term price level, I think we will take out that might be my first target. We take that out, boom, I take my profits. But there's another piece that runs because I see a second target. Maybe the second target is we're going to rise above the high of the previous day. So the first target might be the high from the overnight trade if I'm training the futures like the S&P futures. So I think we'll take out the based on the order flow based on the aggressiveness of the buyers. I think we'll take out the overnight high. That's my first target. Second target is the high from the previous day. And so there are some rules I have around that that give some structure to the trading. So the position management allows us to be flexible with respect to market conditions and of course allows us to add two trades if we see them working out. So we may take out that first target and then sellers come in, but the sellers really can't push it below the open. We had a little bit of something like that in this morning in the S&P trade. If you follow the futures, we open strong and then we have a little bit of a pullback, but we couldn't go below the open price. And so here was a nice, very short-term oversold point where we could put on a position, take out the previous high. So using some short-term indications of overbought and oversold can be helpful in this position management. I use in much of my trading a two-period RSI. So it's a very short-term overbought oversold indication. And when we are oversold at higher price lows, I want to think about being a buyer. And when we are overbought at lower price highs, I want to think about selling. And so the short-term oscillator becomes a decision support tool for some of that cash flow trading. Next slide. Improving risk management. This is so important, so important, so important. One observation some successful traders have made with me is that a large portion of their total profitability comes from a relative handful of trades or a handful of periods of time in the market. In other words, they have some periods where they really make a good amount of money. And then the majority of periods they make a little, they lose a little. Hopefully they're not positive. And they don't have many periods where they have big losses. And so there's a skew where they have a lot more big winning periods than big losing periods. And when we see traders fail very often, it's not that their hit rate on trades is so horrible.  And so we want to be able to break down our trading to see if our average win size is greater than our average loss size. And if we have more winners than losers in our trading. It's not too uncommon that we see someone who has a pretty good hit rate on their trades. They're like 50-50 wins and losses. But again, the losses are larger than the wins. The average loss is greater than the average win. So they lose money on average. That's a situation where they could improve their risk management. Now there are two ways of improving risk management. One is they need to be better at setting stops and utilizing stops that keep losses from getting out of hand. That's the usual way traders think about this. But there's another aspect to risk management that's so important, and that I call opportunity management. Many times, the average win size is not much greater or maybe smaller than the average loss size because the trader is cutting their winners short. They're not letting the winners run to those proper targets that we talked about. And so as a result, they are managing risk, but they're not managing opportunity. They're not getting enough big winners. With the traders I work with at SMB, for example, they have daily loss limits, daily amounts of money that they're allowed to go down in a size position so that they're not going to get stopped out on the day. But if they're trading very well, they want to have some winning days that approach that loss limit. In other words, if their loss limit is $5,000 on a day, let's say, they want to have some days where they're making close to $5,000 or more than $5,000. So that's good opportunity management on top of good risk management. And we can measure that on a daily basis by tracking the outcomes of our trades. The SMB folks use a program called TraderView for that purpose, and I have a link to that on my blog post, my most recent blog post, where it spits out all these statistics for you so that you can see if you're getting more of the big wins than the big losses. And finally, we want to reverse engineer those big wins and big losses. In other words, we want to figure out, what did we do well? What did the market set up when we made a good amount of money so that we can be prepared for the next possibility? And we want to figure out what did we do wrong? What did we miss in the market? What did we miss in our position management when we took big losses? And we set goals for improving that. So by studying, studying, studying our big winners, studying, studying, studying our big losers, we can do more and more of what works for us, and we can improve, improve, improve on what we haven't done well. Next slide. So up to this point, we've been talking about your processes as a trader, generating ideas, managing positions, managing risk. But there's another side to the equation, and that's managing ourselves. And so if we are improving, evaluating and improving ourselves as traders, we want to evaluate what we are doing and it is what we're doing working for us in our trading. So I talk quite a bit about successful traders having routines for their trading. They have routines in the morning hours for preparing for the market day. They have routines for taking breaks in the trading day and they might not be seeing things well or when they might be losing their focus and getting a little too involved in the short-term price action. They have a routine for taking breaks, for calming themselves and improving their focus. Many traders use meditation, for instance, for this purpose. They also have personal routines. So these are routines outside of trading that keep them at their best. And so those routines could involve sleeping well, eating well, physical fitness, doing things in relationships that keep them fresh. Those personal routines are every bit as structured as the trading routine so that we are continually doing the things that keep us at our peak. The idea is to maximize our energy level and our overall psychological well-being. The research in psychology is unanimous in telling us that when we have high levels of well-being, when we have a good amount of happiness and joy, when we have a good amount of fulfillment, when we have a good amount of energy, and when we have a good amount of closeness in our relationships, those four things, we perform better. We have better focus and concentration. We are more creative. We are more productive. And in fact, when we have a good level of overall well-being, we tend to be physically healthier as well. I have a blog post I did some time ago. I'll link to it in an upcoming post. Actually, I think I linked to it. Yeah, I linked to the most recent post. But I linked to it in the most recent post on why energy is so important, and it references one of my other cats, Mia Bella. And the idea here, and this is really an important psychological principle, the idea here is that our energy level determines our access to our strengths. In other words, we have strengths. We have abilities, competencies, as traders and as people. If we are at low energy, we lose our access to those. So we could be a very creative human being, but if we are run down, physically depleted, emotionally troubled, we can't access that creativity literally to the same degree. So by creating daily routines, that maximize our energy, our physical energy, our intellectual energy by stimulating us, our closeness to others. By creating personal routines that maximize our energy, we keep ourselves at a peak for our trading time. So the personal processes are extremely important to our success as traders. And of course the key for our learning curves is putting all this together. So we have ways of improving our idea generation, our position management, our risk management, and ways of improving ourselves as people. That whole package keeps us learning and developing and increases our learning curve so that we have greater odds of being successful and staying successful. So with that, I promise to leave a good amount of time for questions, comments, wise observations. So please, by all means, feel free to type into Bruce and we'll see what we can do. All right. Excellent, Brett. Just excellent. Thank you very much. So, yeah, please get your questions in, guys, and I will read them out to Brett. Brett, in the meantime, I've forwarded or put in the chat for everybody, your trader blog here. And I'm not sure if this is the article you're talking about for the trader psychology and managing your energy. Well, this is one of them. Yeah, there's one that is, if you Google trader feed, Nia, MIA, Bella, trader feed, MIA, Bella, you'll find that post that talks about how our energy level determines our access to our strengths. And the reason the cat's on there is that it was through our cat that I came up with this principle and then found psychology research that Okay, I'm sorry. So, what was it again, if I Google what that? Actually, if you just pull up my current post, my most recent post, and it's linked in there. Yes, so go to most recent blog post and you click there. Yeah, there you go. Perfect, perfect. And look, there's book map. It's linked. And let's see, let's see, let's see. This is it? Yeah, here's the book map. You know what, it's in the previous post. My bad, my bad. Well, where I talk about energy. So, if you scroll down, you'll see the most recent post and it's in there. But a very important concept and happy to answer any questions about that. Okay, let's see here. Well, let's just kick it off and get to the questions. Okay, so, someone's asking about SMB Capital, has an online course, would you recommend taking that course? Have you worked with them, et cetera? Yeah, yeah. So, I work with a number of different firms. I'm not an employee of SMB or Kershner. The two firms work together. So, I'm not an employee of them. So, I don't have a reason here to talk my own books, so to speak. But I work with them because I think they do an excellent job in developing traders. The courses that I've seen have been helpful, have been useful. There are some other tools that they have. I think they're also helpful and useful. Do I think you can learn trading just by taking a course? I am skeptical. I think it can be helpful. I think it can be a great introduction to finding new engines in markets. But, would I take a course to be a successful tennis player or to be a successful basketball player? No, it's a performance skill you have to learn by doing. So, the coursework gives you valuable information, but you have to really learn at the desk. You have to learn with other successful traders to take that information, take that knowledge and turn it into real skills. You know, I teach at a medical school in Syracuse, New York, and the medical school curriculum reflects that. The first two years traditionally are basic science years where you learn anatomy and physiology and you learn about the body and you learn about the processes of the body. And then in your third year you start working with patients. No one pretends that you're going to become a successful doctor just by taking courses in the body. You have to actually learn by doing. And so that's what your subsequent education is all about. They train in some very much the same way. The courses are very helpful. I know the people at SMB. I think they have great learning to share. But that's the first step in your learning journey, certainly not the last one. Okay, let's see here. Okay, users here. Training is much an art as science. It's oriented and he's asking, what can you do on a daily basis to improve his artistic mentality? Okay, yeah. And I work with traders. I do quantify some things myself. There's some very good websites and services that provide scientific quantitative ideas about markets. Rob Hannah does a subscription service called Quantifiable Edges. It's at quantifiableedges.com. And he shares quite a bit of information on his website. There is a service called Market Tells from Renny Yang. This is quite helpful. And there are services available if you go to Quantocracy where you can gather research studies. Yeah, that's Rob Hannah's site. Excellent. And so you can become more scientific in that sense in generating ideas as opposed to relying on quote-unquote artistry. And I find these services to be helpful. I'd be happy to talk more about that, how I use those. But when we talk about developing the art of trading, we're really talking, I think, about the creativity aspect and the ability to see edges that others don't perceive. So for example, in my trading, this gets back to the point about looking at new information or looking at existing information in new ways. I break down any given market into a trend component and into one or more cyclical components. In other words, I look for cycles in the market. But to effectively find cycles in the market, I have to look at a different time series than what normal people look at. Normal people look at like five-minute charts or they look at daily charts. Here, the information I look at is not based on time. It's based on trading volume or it's based on volatility, the amount of movement or the number of contracts traded. The amount of price changes in the contracts traded. And so you're creating different bars altogether. So if you're using volume bars, you are helping standardize the time series by drawing fewer bars during slow periods like midday and overnight and more bars during the busy periods like first thing in the morning. And so evens out the number of bars through the day which helps you identify cycles more cleanly. And so I use the troughs of cycles to enter it up trend and the peaks of cycles to enter a down trend. And so it's a different way of looking at the market and trading the market. There's a bit of science behind it but also a bit of artistry. Okay, excellent. Let's see here moving along. Let's see. Lina from Sweden is asking about how about longer term trend following still cash flow trading? I'm not sure exactly what she means but anyway. Yeah, so you definitely can apply and hello to Sweden. I love Stockholm. My wife and I went not too long ago and the people were wonderful. It's a great place, great place. So any time frame we can do the cash flow trading. So for instance what you would do if you are a longer term trend follower is you would look to lighten up on medium term overbought points and maybe add to positions on medium term oversold points. One of the indicators I look at is from a website called indexindicators.com and they track the percentage of stocks trading above their various short term moving averages. So for instance we can identify the percentage of S&P stocks trading above their five day moving averages or 20 day moving averages. So that creates an oscillator on a medium time frame. So we can be a buyer. Let's say we're in an uptrend. We can be a buyer when the percentage of stocks trading above their five day moving averages goes below 50 and we can lighten up when we get to 70 or above and so forth. And so we can create some rules with some indicators that would help us do some of that cash flow trading even though we're holding core positions over a longer time frame. In fact, that's what many, many hedge fund portfolio managers do. Okay. Good question here about having trouble increasing contracts or size due to fear of losses. How to overcome this? Yeah. It's a common problem with developing traders and what ends up happening is they trade small to avoid losses, but they're trading small also ensures that their profits are small as well. And so they really never develop the confidence to grow their trading. The key here is to increase the size incrementally so that it is not psychologically disruptive. So for instance, if my common position size and I'm just making this up is 10 contracts, I don't want to jump to 20, 30, 40 contracts because the volatility of the resulting P and L is going to translate into emotional volatility. So we want to do that incrementally. Once we're successful and consistent for a period of time trading 10 contracts, then we bump it up. We can bump it up to 12 contracts and then the 15 contracts. And then eventually we're going to get to 20 contracts. But we establish our consistency and our success at the higher level before we bump it up to the next level. And we do that steadily. We do that in an ongoing way so that we're becoming successful at one level, bumping it to a new level, becoming successful at that level, bumping it to a new level. The analogy I've used on my blog is working out in the weight room. We lift a certain amount of weight and we get to the point where we can do three sets of 10 repetitions very well at that weight. And so we bump it up to the next weight. We don't go from lifting 150 pounds to lifting 350 pounds. We go from 150 to maybe 175. And once we can easily do three sets of 10 reps at 175, we bump it to 200 and then to 225. And that's how we build our strengths in the weight room. That's how we build our trading. Okay, excellent. We have a trader here.  He's talking about or in your book you had written that a lot of traders are not clock punchers. They're following kind of flow or state here. So in terms of personal relationships like with his girlfriend here, overcoming guilt, being at the screen all the time, any tips for trying to deal with that? It's a great question. It's a great question. And it's precisely because of what I was mentioning in terms of maximizing our energy that we do have to nurture our relationships and our other interests. If we spend all of our time day after day in the screens, guess what? We're going to burn out. And when we are burned out, we don't have creativity. We don't have focus and concentration. Our trading suffers. So it depends on the types of trading we're doing. But even the short-term traders I work with, and I trade short-term myself. I wouldn't call myself a scalper, but I trade short-term. But even the short-term traders in my own trading will take a break midday, get away from the screens, and start to refresh, rejuvenate. That could be done with physical exercise. It could be a power nap. It could be talking with someone we're close to and just re-establishing the bond. So that all works. That can keep us fresh for the afternoon then. In fact, as I've discussed with many traders, a practice that has worked very well since I observed it in Chicago when I first started working with traders is that they will break the trading day into two trading days. Morning will be a trading day in quotes, and the afternoon will be a trading day. And they keep a separate P&L for the morning trading and then a separate P&L for their afternoon trading. And they take a break in between to keep themselves fresh. But then, once the market closes, so does their screen, so to speak, yes, they go over their trading and yes, they will prepare for the next day. But in fact, they close the screens down and they exercise other strengths in their lives. And so they use the time after trading to have quality time in the relationships, quality time with their kids, with their spouses, with their significant others, quality time and physical exercise, having fun, doing things with friends. And yes, they'll use time, maybe the next morning to research new ideas and to review their trading and so forth. But each day they are doing something to stay connected with quality time to the people who matter to them. So they're nurturing their relationships. Without that, like I say, it's very easy to burn out. Okay, excellent. Another question here about coming back from traumatic experiences, how to overcome that and trying to get back your losses or get back at the market. Yeah, with good risk management, we never have traumatic losses. We have losses, that's for sure. But we don't have traumatic losses. One of the important aspects of risk management is keeping our losses down to the point where they don't traumatize us, where they don't so interfere with our psychology that we can't make good decisions going forward. And so as I mentioned, day traders will have daily loss limits. They have monthly loss limits.  All to avoid being traumatized. So the best cure is prevention, just like in medicine. We want to have risk management rules where the losses that we take, the size that we trade out and the losses we take are manageable. If we do become traumatized, the only way to overcome trauma and you can look up Google Trader Feed and Trauma and you'll see, I'll suppose, the only way to overcome trauma is through safe, successful experience. So what I have done with traumatized traders and what I have done with myself when I've gone through difficult losses is literally go back to trading on the simulator. And yes, you know, it's tumbling and it might feel like a step back but in fact, by taking the P&L out of the equation, we can focus on trading process and making good decisions and we can get back in the rhythm of making good decisions and then we start putting on small size and we start making money and then we put on somewhat larger size and we make money and that's how our confidence grows back after something that has shaken us up. Okay. Another question that's kind of related here but any suggestions on techniques to employ during the trading session when you have suffered issues or losses early in the session, then that affects your risk appetite for the rest of the session. So how do you regain your focus? Yeah, another good question. So I'll tell you what I've done in my trading that's been super helpful. I track my trades as a function of time of day. So we can look at trades that we enter between, I'll use Eastern Time, between 9.30 and 10. What's our hit rate? What's our success rate with trades between 9.30 to 10? 10 to 10.30, 10.30 to 11 and so forth. Okay. And so I know historically that if I place trades early in the New York session that 9.30 to 10 period, the success rate is relatively low because we have lots of different flows coming in and out of the market as buyers and sellers sort themselves out early in trade. So I know that my hit rate is on a lower side. So I will specifically size my first trades on the small side. I'll look for a good entry. I'll look for a good idea. I'll size it purposely on the small side and then if it gets started and it stops out, I use that as information that maybe the flows are going a different way. I reevaluate the market and if I see, this is like in today's market, the sellers early in the session couldn't push us down past the open. If I see that then I will flip my position and enter with larger size during a time of day that has worked better for me. So you're using the early losses as information and it's easier to do that when those positions are not sized very large. If you are incurring losses early in the trading day that are impairing your risk taking later in the trading day then you're probably sized too large early on. Okay. Yeah, Brett, I'm just going to jump over to book map very quickly here because what you had mentioned early on really struck a chord with me and relates to this answer as well. And that is the something really rather unique I think here in book map is the I found it just so helpful and other traders have mentioned it as well how you can track all of your orders. It's over time here. So just like the way book map is showing the liquidity and volume over time here so is your trading. So for example I'm moving some of these entries here limit sell orders or limit buy orders here but I can see all of my actions. So this is when I entered with this beige dot here with this limit buy order and this is when I moved it here and now it's up here at this 2901.5. So going back in debriefing your trading after this is so helpful be able to understand and be accountable for precisely what you were doing like you have to hold yourself to it. Like these were my actions. Why did I do it and you can't really escape it. Yeah, that's very nice Bruce where you can go back to the screens and see what you did when and review that and look at what you might have play what you did well. So it all shows up there on the screen. Very, very nice. Yeah, yeah. It's been really, really helpful to debrief and then learn from your trading activity. So anyway, I wanted to mention that. Let's jump back into the questions here. Let's see here. The next question was regarding besides meditation and listening to complex music what type of diet supplements or anything to help improve your focus or intuition or trading performance that you recommend. Yeah, yeah. In terms of focus I do think the meditation work can help. There's biofeedback work that I mentioned in the blog. Certainly eating well eating the right things does our blood trigger levels affect our focus our concentration and so eating in a healthy way and regulating that could be very useful and I find that taking frequent short breaks from the screens and getting away coming back with fresh eyes that can pace us through the market day just like we would pace ourselves in a distance race and that can very much help.  All of those are things that traders do that I work with that help them. Some traders find an environment where they're constantly interacting with others to be very helpful others find it tremendously distracting so you've got to figure out what type of environment for you brings out your best decision making. Okay, there was a question about that as well about how to start to develop your networking any recommendations. Being visible online is a great way so if you join services you participate in online conversations there's there are a number of trader related groups that are out there and participating in their events and in their discussions could certainly be one way of doing that being active in Twitter following people and interacting with them in that way could be very, very helpful. But I would say seeking out trading communities looking for communities that are doing the type of trading you'd be interested in and following some of the people by Twitter who are posting on topics that are of interest also reading trading related blogs there are some really good blogs and podcasts and you can quickly figure out who's doing some quality work and reach out to them that's very helpful. Okay, and I've put in the chat here several times for everybody Brett's blog here and some other links that he's referred to so you guys can come back or click on that and visit his blog here as well as some of the other links as well. Let's see here. Brett, I appreciate that. Yeah, we're moving on in time and maybe one more question. Okay, yep, sounds good. So sorry to everybody if we didn't get to your question here. Let me just take a look here. Is it equally important to identify your state of emotion when entering or exiting a trade as compared to the profit and loss of a trade? It's a good question and self-awareness is really important and so being aware of our state and are we agitated? Are we focused? That's very, very helpful because if we see that we are in a disrupted state either because of distraction or emotional arousal if we see that we are disrupted we can stand back and say, wait a minute this is not the state in which I make my best decisions let's calm down and look at the market fresh and decide what to do. On the other hand if we're in a good state and we see that we've hit a target and we act on that that's great. You only want to be focused on the market psychology the trading psychology when that psychology could interfere with your best decision making. Yeah, it's an interesting question relates to making a distinction between profit and loss and your emotional state. Either way, we could be disrupted, right? Correct. Okay, so in the end the overriding principle here is emotional state. The overriding principle is that you are aware of yourself at the same time that you're aware of markets and that you are using that self-awareness to step back from trading when you're not in your optimal state and that ability to step back and recognize when you're in the wrong state is something that develops with time and is something we can systematically work on journaling in our goal setting. But the broad issue that we're talking about today is observing our trading evaluating ourselves as traders learning from mistakes learning from what we do well and structuring our trading in such a way that we're making continual improvements. I wish everyone and I appreciate the opportunity to get together. Yeah, thank you very much, Brett. This is excellent. I just wanted to mention to everybody there's been some a lot of thank yous in the questions here, Brett. So very, very, very appreciative here. And just wanted to mention everybody we will tweet out the recording when it is available on our Twitter feed at bookmap underscore pro so you guys can check out the recording. Okay. Brett, thank you very much. We really appreciate it. Okay. Thank you for organizing this. Okay. All right, everybody, take care. Bye-bye.


So tonight I want to talk about this issue of the elections, you have seen the UPND cheating themselves, they have really been cheating themselves. You know kuyun fuysha hui no, you know fidya kuyun fuysha hui no ave, they have been sweeping the elections and they are bubbling with confidence that they are becoming popular. Now let's be real here, let's be real, let's be realistic. How can you say UPND is becoming popular? Honesty, even you people who are watching, even whenever you PND, including in the HL, if you ask yourself what is it that you have done which would make the people of Zambia to love you PND, what have you done? What have you done, what have you done? Let's be real, let's ask these questions. What has UPND done for the Zambian people to love them? What have they done, what have the UPND done? Since they came into power, what did, what have they done? I am not finished my dear sister, I am just starting and I am gonna go far and wide. Far and wide believe you me, I am not finished, if you think that I am finished, ḤċĄlĩċĊn ʂĀĀĀlĦąa ʋĀĀlĩąa ʋĀĀlĦąa ʔĀĀĂĂąa ʔĀĂĂąa ʔĀČĄlĳąa ʑĀĀĆČĄlĳąa ʔĀĄĆĄąa ʔĀĀĀąa ʔĂĀąa ʔĀĀĆĈa ʔĀĀąa ʔĀĀĂąa ʔĀĂĆĊĄČĄ ĀĀĂĂđĂ ĀĂĂĂ  chromosdāma                                                                                ៛個人 ្i ʀ̓ant ្i ៛ʀ玉 ʄ̇tell ប្'ʄži ែʀʀuʀ backlog made ajuda, ភʀoʀ ʓalɗ hʀi ʜʒʀoʀʀ suis lʋuʀ ʀˀʀ ʀʀeʀ end dimension nuanced ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən і ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən ən  ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ ḣ � Book science Lower This Ong You are sold You don't even know Yes things are bad But you don't even know Why things are bad You don't know How you can find the solution Wyoming What Old things Are dis helped in our country They don't know ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ ḍ � is to instill fear using the police and the courts. That's what you have done. Seismically you have instilled fear in all of us such that even in a fawaii vi kisha apu to aritina, to aritina, you managed. You managed. You wanted to open my shield and power. You arrested me ten times. Ten times. Ten times. Since you came into power in just two and a half years two and a half years, you have arrested me ten times. Ten times. I go to court every week. Every week I go to court and not one day. Two days, three days, four days, every week. I can't even work. I can't even work. I'm very into work. And who doesn't which opposition leader which opposition leader doesn't have a court doesn't have a case in court. Who doesn't have a court, a case in court. So you have instilled fear. That's what you have done. So that people don't talk. And why don't you want people to talk? You don't want people to talk. Even when you read elections like these elections which happened yesterday, you read elections. 2021, you reeked those elections. You reeked those elections. You reeked those elections. I would objectively say yes, Ed Galungo lost the elections. He didn't. How kind of HLM. Let me put it this way. How kind of HLM got more votes. But certainly how kind of HLM did not get more than did not get one million votes more than Ed Galungo. No, he got one million. He got one million votes. He got one million votes. You remember, at one point I seculated the figures over the elections result. And we can't account for about 630,000 votes. About 630,000 votes cannot be accounted for. So, me I agree that how kind of HLM got more votes. But he did not have one million votes more than Ed Galungo. Because they are about 631 votes which are not accounted for. You reeked the elections. You reeked the elections. Very simply you reeked the elections. And somebody will say no. But they were not in power. Yes, they were not in power. But they reeked the elections. They reeked the elections because they became complacent. But Ed Galungo became complacent. But Ed Galungo was looking at so many things that they did. And they were very sure that now with all these things that we have done for the people, people who put us in power. They underrated the machinery of the UPND in terms of propaganda and of course reeking the elections. Therefore, me I agree that by Ed Galungo underrated the machinery of the UPND. UPND employed a serious machinery, scientific machinery to dent PF. They were working with think tanks. Think tanks, big think tanks. Think tanks like They used Facebook to make sure that they disseminated ferocious propaganda which corroded the UPND, the PF to an extent that they looked like they are so bad people. They look like they are so bad people. A lot of us started looking at when we think of Ed Galungo. We used to think to say we are working with the people of the UPND. But we never think that Ed Galungo underrated the machinery of the UPND. And they don't understand the fact that Ed Galungo underrated the machinery of the UPND. Because of lack of resources. Because of lack of resources. Because of lack of resources. ᜋ ᔜ ᕓ ់ ្៬ información ្៛ ្ ៦៬ ᔃ ្៫ ፶ᒳ ᒕៜᔤ ្ ្ ្ � troubledcy. ᐜ ៌ ្ ្ ៓ ្ៜ ្ ្. ឰ ្ ៉ ្ ្ ្៘ ឱ Გ្ ្ ្ ្ Empire of mount Ellarda� enroll. north western province a number of people were being chased from the polling station even in some areas they were being chased some of them were being bought so it was freely UPND was free to just putting pre-marked ballots pre-marked ballots and you can say where did they get the ballot papers of course they got them from ECZ they got them from ECZ they got them from ECZ and the people that were in the field were overtaken by UPND some of them were falsely overtaken some of them were paid it was a full machinery to rig that election and this is real now they defy by UPND it's real look there is one first of all excuse me how can I I want there is one which I saw there is one like even if you see you can check this I am in an elections inquiry yesterday you can check but those ECZ forms I don't know what form I will post that form the people that are signing there the election monitors are supposed to sign but you just find that all the sign of a new morph UPND but what about these others we even come up with because of shyness because they want to appear these elections are free and fair now what they have started doing they are giving votes to some little known opposition little known opposition opposition political parties that are not even known they are giving the mama votes why they are giving the mama votes they are giving the mama votes so that it looks like it is democratic and this is what they want to do even in 2026 whereby they will have some stooges of presidential candidate to stand and they will give the mama votes meanwhile they give so many votes to a candidate they are doing this they are testing that method of distributing votes to some political parties so that especially PF so that PF looks like it is completely dead if you look at the elections of yesterday the whole propaganda the whole notion that they are trying to create is that PF is dead that is what they want to create if you look at all the results PF yes you will say it is Mao Sampa it is PF of Mao Sampa it is true it is PF of Mao Sampa but the idea behind the UPND the agenda behind the UPND is to make sure that PF looks finished that is what they want


we had a long time wait at Walmart because someone has to be someone that needs to be they need to be 21 order to bring me up the echo so they have a way for somebody with that damn guess what else happened they lost one of the baskets for the order Diddy Cannon back today with another doing this video huge shout out to everybody too and if you are a subscriber make sure you subscribe button give me a thumbs up and do not skip those ads it is May 4th and it's time to get to this bag in this video a lot of things happen and not only that they were very very very slow either way go we got this dough we are we got off like around 105 110 somewhere around I don't even remember either way go you guys wanna make sure you stay tuned to the full video smash that subscribe button give me a thumbs up and do not skip those ads also if you want chance to win some of the free merch all you have to do is email me at gromeshouseofviesatgman.com send me a business source, subscribe to the channel and earn your chance to win it's time to go get these divoties let's get it order number one it's time to get it done all right Sam's Club one order 4.1 miles for 1703 let's go get this cheese how you doing this morning I'm doing great I can't complain at least it ain't raining today yeah all righty thank you have a great one it's all the way sparked up water we're putting up the dolly baby putting up yeah it's gonna be coming handy slide over here with the doll these tires I need to see these tires right here hello oh I'm getting it ready for you I had to pull off the dolly cuz I didn't want to have to carry all these sodas over here if you don't mind ma'am I could just sit the sodas right here to make it easier for you yeah my kid move them from there that's where you have kids huh my mom used to always make us get up to turn turn the TV or go get her to remote and we in whole another you're welcome you have a great day ma'am we're number two what do oh Walmart to orders 4.3 miles for 2372 forget you and your crew we're about to go pick up this dough you already know let's go I'm doing great I can't complain I'm still living man it ain't gonna change that it ain't gonna take nothing to do whatever you got to do I appreciate y'all y'all have a good one yes sir if you don't come back to get busy busy baby it's time to drop off order number one y'all know we about to get it done and we might have some fun or we might not you never know but we have to get this dough you already know let's go all that right I'm gonna make a doorbell on top order number two what it do is only like two items they got some parents or something else they're about to get busy they got the baby let's drop it like it's hot let's drop it like it's hot step back I don't want to follow smack order number three is instant crime one item 6.3 miles for 1840 shorty order number four is all Walmart to order 6.5 miles for 2014 it's time to go get this green let's go we are here baby drop off order number one it's time to get it done and we about to have some fun and we about to get this money and get on the run baby they got a lot of other extra stuff so we're gonna drop this and then go back and take another trip hopefully it's only one more trip off the road and then we did baby drop it like it's hot, doorbell, knock on the doorbell what's he kissing? I want to come out here and get busy you know what I'm saying? it's time to get these banged you know let's go get busy baby we on the main street too I went to the wrong address too because I couldn't see it I went to the house next door then I had to turn around and come back with the way it go we ain't complaining we maintain it we doing our thing and we switching lanes I changed lanes switching lanes this joint got a hole in it too let's grab all these bags with my hand so we can get these bags man drop this off then we got to go throw off the other order and get in order baby drop it like it's hot, knock, knock, step back with the phone on smack we gone order number two what it do it says we're in the door but it's gonna come down and get busy baby hopefully don't take too long we time to get it on baby I kind of got lost a little bit around here and it's a complex because the numbers just jump up I guess they're coming down let me sit on the first floor order number five we getting this money we ain't telling no lies baby Walmart 2 orders 4.6 miles for 1985 if you keep on going you gonna get the prize let's go did you order a Walmart order look where you are you're two minutes away oh but I'm here already how are you I'm doing great in yourself yeah you can put it here please okay you got your key which we can open the door okay I want to make sure because it's not working it's going to stick no no no it's just one more oh it's still open the door okay it's a good thing nobody just knocked out Jackson because coming in I'm coming by myself okay and she uses the code and I was worried if you know I had this code right I had never I would go to the master bedroom I would go to the master bedroom okay no it's fine for me it's fine okay you're doing it how are you that's everything man you have a great day I guess I drive fast huh yeah you have a good day ma'am you too thank you order number two and what it do almost trickle that stick baby get the way it go we about to get in the mix baby it says something about the green bin in the driveway so I'm just going to put this stuff in here that's what we doing baby it's kind of actually a small idea it's juicing it I'm going to put it down here let's get it make sure they can get it so they don't get hit by the the screen so we do our thing reverse it smack it 2.9 miles for now I know three we about to go one up there and we about to get this cheese and it's going to be a breeze let's go I ain't been here in a long time be on the ground how you doing I'm doing great I can't complain you guys have a good one it's Jersey Mike we about to get him right baby it says do not ring the doorbell hit him with the photo we going we getting money this is a big order but we got to do a man we ain't getting all the way sparks up so we got to get this money somehow baby 4 more 3.9 miles for 975 hopefully it has a hidden tip off the rip and we get this money real quick let's go this order to get in the order baby you know we put out this dolly man they got zip pops, good bars and the whole night we put that dolly I was about to get a dolly if y'all ain't got one I'm going to say y'all a lot of tricks but this ain't just a dolly we got a lot of stuff guys hopefully it gave us a hidden tip that's what I'm hoping but we never know I didn't have my pair on either so I already don't know and the last time I had it on it didn't really work out the greatest for me so to each its own everybody got a different way of doing things y'all know we about to get this green nothing in between they parked right come on y'all got to be stuck doing that y'all want to know somebody come and deliver try to park somewhere else so we can come through and get busy the dolly fit through anyway though time to get this cake move this chair it's probably when they get the door dash doors in that doorbell bingo bingo drop that go back and get busy y'all like wait me hold y'all hope y'all out there dash and get this money and guess what else I had to take off that uh that vest man it was getting too hot for me baby it was getting hottest fisheries even though there ain't that hot more on my side that sun beaming though get that back maybe a little back probably getting all the way sparked up but I don't even know it let's go yeah that wasn't that good that wasn't that good of an order let's get back in order baby in this last bag let's go get to this bag baby why they hating cause they mad baby they a little sad baby something like it's hot get that phone step back in the photo smack we gone order number eight we trying to get back to this cake aww one more two order seven miles for twenty one forty one you know we gonna get it done I'm gonna tell you guys this right now this order is very very bad guess what first off one of the orders is twenty eight items and it contains alcohol so we gotta get that ID and the second order is a large order and it's seventy seven items baby but you do that go we gonna run up to this no you already know cause it's kinda going slow but I don't know let's go let's go they got that wine diggity too hello how you doing this morning what's afternoon now can you bring this stuff right into the door here yes ma'am that's what's your order were you here before or no no ma'am this would be good right here I don't understand no big deal put it in the basket if it's easy whatever's easy for you put it in the basket it's the whole bag if you can put it in the basket yeah this also they asked me to get your ID for the wine you know I tried to order the cigarette but I wouldn't let you do it really? what's the trick I don't know I might have to put the information in I'm not sure I've never delivered cigarettes before well I'm desperate my husband's in the hospital and I don't know if he's going to be able to even drive when he gets out if he gets out I'm sorry to hear that yeah the city driving is hectic yeah I'm just saying as a kid the theaters were all there yeah and you get right to the theater a lot of you know all these crazy Godzilla and all this stuff uh huh I could put the wine in everything right up here so it's easy for you put this right here and then put this one right there and then I think it's one more right here I really appreciate this yes ma'am no I don't have any change we should carry some for people like me yes ma'am that's everything I'll try to make it as easy as possible that's why we got the bag she came up with the great plan sign up for the bears that's fine I'll remember you if you can sign there ma'am my finger yes ma'am is there a gas station close by here if you turn right and go over to 120 there's a little strip mall right there and they sell cigarettes there if I gave you the money would you get them yes I will look at this we are here dropping order number two what it do this stuff is everywhere I gotta try to I'm trying to get busy to get this first bag open up the club gates get that out well this was a terrible order but it's all good though baby you gonna keep on getting busy I hope you guys are with me my business partner did order number nine and ten I'll tell you guys that when we get back in the car whenever that may be we got all this stuff baby 77 items just in case they want to come over here and get busy hey doggy dog hey dog I'm trying to get all the way first up again she got all the way first up twice before I can even do just one order cause the drive was like kinda country it was a little strong baby and we had a long time to wait at the uh we had a long time to wait at Walmart because someone has to be they need to be 21 in order to bring me up to alcohol so they had to wait for somebody with that then guess what else happened they lost one of the baskets for the order for one of these orders so they had to find that then they finally came out but I was waiting there for like 20 minutes low key I said a cancel but I'm trying to get this money understand understand that's trip off the rip out of control guys sheesh it didn't seem like it was that much when he was bringing it out but it's super critical we gonna keep on moving and grooving we gonna step back hit him with that photo order 19 we did these two orders now it's time to spin order number nine is Walmart 2 orders 3.2 miles for 1934 order number 10 is Walmart 2 orders 3.8 miles with 2764 you know we got that dough and we got an extra $10 tip off the rip and just like that it is the end of the video we came, we saw, we conquered we didn't really go bonkers we got 201 53 get with me baby look at the time wow it's 1 on 4 and I ain't even gonna lie today went very very slow to me baby this is the way it go we came we saw we got it done I hope we got it during the video if you want to win some of the free merch all you have to do is email me at wrongtimesofusagemer.com send me a picture of yours and subscribe to the channel and earn your chance to win lock in cause guess what tomorrow we getting it back in again I'll see you guys on the next one we going, we going, we flowing you already know it it's VDK and I'm on my way


Hi, my name is Jason Stover. I'm the product marketing engineer, microcontrollers for ST out of Boston Market and I'm here today to show you a demo based on our brand new L4 Plus which has the Chromart GRC built into it. If you take a look at the L4, it's our first implementation of Chromart we've had on the F4 for a number of years which is elementary GPU functionality. The L4 Plus also has double the flash and double the RAM along with an increase in the MCU speed by 50% going up to 120 MHz. With this you can do something like a watch or a simple graphics display or a QVGA built on an M4 using a minimal amount of power. It's based on a third-bit RISC core. It has advanced graphics controls and we have a number of free tools that enable you to design the functionality along with license-based tools. So if we look at the actual board itself you can see a circular graphical display, the L4 Plus and what you're looking at here is a series of implementations based on the software package. So if I was to swipe you can see right here we have a stem win.  If I flick you can see the video if you want to play, a microphone, something to that effect. If I hit the reset I go back to the basics. I can select something else such as let's go to embedded wizard. Again you can see something like a heartbeat running. Again this is all designed with the tool itself. Something like a graphics display on a map.  Again this is another tool that you could use. You can see here you can see music, see embedded. Something like a watch face. Again you can see something simple like shading, something like a simple analog watch. Again just to give you an idea that with the demo platform you have several solutions that you can use to implement the actual software itself. In conclusion I appreciate your time. Thank you very much.


In this video, I will describe the process of antibody-mediated immunity, also known as humoral immunity, describe the role of helper T cells in humoral immunity, describe the process of clonal selection of B cells, describe the role of plasma cells and memory B cells, and describe the structure and function of antibodies. Here we see the antibodies, also known as immunoglobulins, have a structure made from two heavy chain polypeptides and two light chain polypeptides. The FC region of the antibody is the constant region, whereas the light chain as well as a portion of each heavy chain forms the variable region of the antibody. And this variable region forms the antigen binding site. The variable region is different for all of the antibodies produced during the initial process of B lymphocyte maturation to make an enormous variety of different B lymphocytes that all have a distinct antigen binding site on their antibodies. However, during clonal selection, when a B lymphocyte is activated to divide and make more B lymphocytes, all of the B lymphocytes produced during clonal selection will make the antibodies that have the same antigen binding site and can therefore defend against the same specific pathogen. Here we see the example of clonal selection for B lymphocytes or B cells, where we have three hypothetical examples of naive B lymphocytes using different colors to distinguish the different shapes of the antigen binding site of the antibodies on these naive B lymphocytes. The blue, red, and purple antibodies bind to different antigens, so the specific antigen shown in the illustration can only bind to the red antibody and not to the blue antibody or the purple antibody. So there's trillions of distinct lymphocytes with different shaped variable regions of their antibodies enabling the body to potentially respond to an enormous variety of different antigens from any pathogen we might be exposed to. But when we're exposed to a pathogen, the antigen from that pathogen can bind to the antibody on the surface of a specific lymphocyte leading to activation of that lymphocyte. That lymphocyte will proliferate, it will divide to make more B lymphocytes that all produce the same antibody. So here we see the formation of clones where the activated B cell divides making more B cells that have the red antibody. Some of those cells will be the memory B cells that are long-lived B cells providing immunological memory in case we encounter the same pathogen again in the future. But many of the B cells that are formed will be the effector B cells known as the plasma cells or plasma sites. These effector B cells secrete antibodies. The plasma cells are secreting antibodies and the antibodies then are responsible for antibody mediated immunity when antibodies bind to antigen on the surface of a pathogen. They can help label that pathogen to direct the innate immunity to help defend against that specific pathogen. So the innate immunity can be recruited by the adaptive immunity. The antibodies can also just work to neutralize the pathogen or help to stimulate defense proteins that will help to destroy that pathogen preventing the infection from spreading or helping to eliminate the infection. And so during the primary response both memory B cells and effector cells are produced and then after the infection is cleared most of the effector cells will die but there will still be the memory B cells circulating in the body and found in the secondary lymphoid organs and those memory B cells can then become activated if we're exposed to the same pathogen again and this will lead to a much more rapid response to produce the effector cells and secrete antibodies to defend against that infection the second time we're exposed. So there's a T cell independent mechanism for activation of antibody mediated immunity and this requires a repetitive antigen. The epitope refers to the specific binding site of an antigen where the antibody can bind to and if there are multiple binding sites for antibodies that are repetitive on the surface of a bacterial cell this can lead to the activation of a B cell independent from a helper T cell. So the crosslinking of antibodies that are on the surface of the B cell the crosslinking of B cell receptors by repetitive antigen will lead to activation of that B cell clonal selection of the B cell producing both memory B cells and plasma cells and then those plasma cells will secrete antibodies. You can see here the form antibody secreted by this plasma cell is labeled pentameric IgM and so IgM is one specific subclass of antibodies. IgM forms the B cell receptors on the surface of a B cell but IgM is also form a secreted pentamer meaning five antibody proteins are linked together and these pentamers then are very efficient at binding to extracellular pathogens and causing them to clump together which is known as aglutination and that clumping will help to enable the immune system to clear the infection from the body. T cell dependent activation of antibody mediated immunity occurs when an antigen that is not repetitive binds to the B cell receptor. The B cell will perform phagocytosis to engulf the pathogen bringing that antigen within and then package that antigen into an MHC2 protein so the B cell will then become a professional antigen presenting cell using the MHC2 protein to display antigen to a helper T cell that has a CD4 T cell receptor complex. The activated helper T cell then releases cytokines that complete the activation of the B cell so now that the B cell is completely activated it will divide go through clonal selection making the effector plasma cells as well as memory B cells during an initial exposure to a pathogen there are no memory B lymphocytes there are are only the naive B lymphocytes and when a naive B lymphocyte becomes activated by exposure to a pathogen it will produce memory B lymphocytes as well as the effector plasma cells that secrete antibody so we can see that it over the time course of the initial infection the antibody concentration of the blood gradually rises and then when the infection is cleared the antibody concentration of the blood will fall but not all the way back to zero there will still be some memory B cells that are long lived and then on a secondary exposure those memory B cells will become activated more quickly and produce a stronger secondary immune response where lots of plasma B cells will be produced to secrete antibodies there are five major classes of antibodies antibodies are also known as amino globulins and so the major classes of antibodies are IgM or amino globulin M IgG IgA IgE and IgD the IgD monomer functions as a B cell receptor embedded in the plasma membrane of B lymphocytes there's also a monomer form of the IgM antibody that functions as a B cell receptor however the IgM antibody also forms pentamers as is shown in the illustration here where five IgM antibodies are linked together and the pentamer form of IgM is the primary form of IgM that is secreted by plasma cells the pentamer has 10 antigen binding sites enabling the IgM pentamer to be very good at creating clumps of antigen in a mechanism known as agglutination IgM pentamers are also very good at activating the complement system the amino globulin G or IgG monomer is the primary form of antibodies that are secreted by plasma cells and so plasma cells secrete IgM during the early phase of the antibody mediated immunity and then class switching occurs where plasma cells start to secrete more IgG monomers you can see the majority of the antibodies in blood plasma are the IgG monomers approximately 80% of antibodies in blood serum are IgG IgG is particularly efficient at activating phagocytosis in a mechanism of opsonization where the phagocytic cells have FC receptors that bind to the constant region of the IgG antibody IgA is the primary form of antibodies that are secreted by exocrine glands and secreted onto mucus membranes IgA is a dimer where two IgA antibodies are linked together creating a structure with four antigen binding sites IgE is an antibody that is particularly effective at stimulating the inflammatory response IgE activates mast cells and basophils that release pro-inflammatory mediators like histamine to stimulate inflammation IgE antibodies contribute to allergies by promoting inflammation when they stimulate mast cells and basophils IgE antibodies are also efficient at stimulating antiparasitic activity when IgE antibodies bind to antigens on the surface of multicellular parasites they can stimulate the activity of mast cells basophils and eosinophils that are effective at eliminating these multicellular parasites here we can see the time course of the antibody mediated immune response to a primary and secondary exposure to a specific pathogen before you've been exposed to the pathogen there's essentially no antibodies in the blood that could defend against that specific pathogen but after the primary exposure it takes around two weeks for the concentration of IgM to rise in the blood and it's around three weeks before the concentration of IgG reaches its maximum and so the primary immune response is relatively slow in contrast to the secondary response when you're exposed to the same pathogen a second time after having already formed an adaptive immune response to that pathogen it will take less than a week to start producing the IgM antibodies and by 10 to 15 days the concentration of IgG in the blood is much higher than was seen during the primary response by three weeks this illustration shows us the mechanism of IgA antibody secretion by mucosa associated lymphoid tissues the pyrus patches are mucosa associated lymphoid tissues found in the small intestines when antigens are encountered by lymphocytes in the mucosa associated lymphoid tissues this can lead to activation of the antibody mediated immunity where plasma cells will start secreting antibodies and some of the antibodies secreted will be the immunoglobulin A IgA secretory antibodies that will be secreted along with mucous through the exocrine gland at the mucous membrane these IgA antibodies can then bind to antigens on the surface of pathogens that are trying to enter the body or an infection that is at the surface of a mucous membrane IgE activates mass cells and basophils to promote inflammation and this mechanism can contribute to excessive inflammation producing the symptoms associated with allergies so and the allergy is an immune response to an antigen from something like a dust particle or pollen or some other antigen that's not actually associated with a pathogen but instead is being associated with something that would not cause an infection and be harmful but is just part of the environment that the immune system has recognized as foreign and has started to mount an adaptive immune response to try and attack in the illustration here we can see that an allergy could start with a phagocytic cell recognizing the allergen and performing phagocytosis engulfing antigens from that allergen and then using the class 2 MHC protein to display antigens to a helper T cell the helper T cell then will release cytokines that stimulate the immune response including helping to complete activation of a B lymphocyte this B lymphocyte has its B cell receptor activated first by antigen on the surface of the allergen and then the cytokines from the activated helper T cell complete activation of the B lymphocyte then the activated B lymphocyte will go through clonal selection proliferating to make more B lymphocytes and some of these will be the plasma cells that secrete antibodies some of the B lymphocytes will secrete the IgE antibodies and the IgE antibodies then can bind to the antigens on the surface of the allergen with the antigen binding site of the IgE but the constant region of the IgE antibody will bind to the FC receptors on the surface of mass on the surface of mass cells and basophils so mass cells that are resident inside tissues will then become activated by the allergen and start to release their inflammatory signals such as histamine which will contribute to the symptoms of the allergy neutralization is one of the mechanisms through which antibodies can help defend against infection here in the illustration we three see three different examples of neutralization where an antibody binds to a pathogen or a toxin from a pathogen and helps to block the harmful effects of that pathogen so on the left we see a virus being neutralized by antibodies when the antibodies bind to antigens on the surface of the virus this blocks the virus's ability to enter our cells neutralizing the virus preventing it from being able to spread infection in the middle we see the example of antibodies binding to a diphtheria toxin a toxin secreted by bacterial cells the diphtheria toxin needs to bind to receptors on our cells in order to have a toxic effect when the antibodies bind to the toxin this prevents the toxin from binding to receptors on the surface of ourselves neutralizing the toxin and preventing its toxic effects and then on the on the right here we see an example of antibodies binding to the flagellum of a bacterium and so by binding to that flagellum the antibodies are preventing the bacteria from being able to move efficiently through the body slowing the spread of the infection a glutenation refers to the clumping of antigens by antibodies here we see the IgM antibody has multiple antigen binding sites making it especially efficient at a glutenation so most antibodies have just two antigen binding sites but IgM pentamer has 10 antigen binding sites making it very efficient at a glutenation clumping together the antigens in this case we see bacterial cells are clumping together in the mechanism of a glutenation and this clumping will help prevent the spread of infection as well as making it easier for other mechanisms of the immune system to come and target this bacterium and remove it from the body opsonization is when a defense protein marks a pathogen for phagocytosis and so while the complement proteins are capable of functioning in opsonization antibodies also serve as labels for opsonization the FC region of the antibody the constant region serves as a tag that is recognized by FC receptors on the surface of phagocytic cells like this macrophage so when the FC receptors on the macrophage bind to antibodies on the surface of the pathogen this will stimulate the mechanism of phagocytosis antibodies can also stimulate complement fixation in the classical pathway for activation of the complement cascade antibodies mark antigens on the surface of the pathogen leading to the activation of the C1 complement protein and C1 will then stimulate C2 and C4 to activate C3 and from that point on C3 will then join together with C5, 6, 7, 8, and 9 forming the membrane attack complex a portion of C3 will also function as a chemokine attracting phagocytic cells to come and engulf the particles that remain after the pathogen has been killed by the membrane attack complex antibody dependent cell mediated cytotoxicity is when antibodies label antigen on the surface of an extracellular pathogen or a cell infected with an intracellular pathogen and then this stimulates either natural killer cells or cytotoxic T cells to release cytotoxic granules activating apoptotic cell death in the extracellular pathogen or cell that's been infected by an intracellular pathogen so this illustration shows us the example of antibody dependent cell mediated cytotoxicity where an antibody on the surface is labeling either a pathogenic cell or a cell infected with an intracellular pathogen and those antibodies are helping to stimulate activation of a cytotoxic T cell that can then release cytotoxic granules containing perforins and granzymes that activate the apoptotic cell death mechanism in the target cell whether it's a extracellular pathogen or a cell of our own body that's infected with an intracellular pathogen


Hey, what's up you two I'm Zeke and welcome to the dream green show in this episode I'm bringing you guys the top 6.5 stocks to buy in the month of April as you guys have seen last month The market has just been pulling back pulling back pulling back and I've been telling you guys that the stock market It's like a bow and arrow We've been pulling it back so far that now in April might be the time to release that bow and the string It's gonna shoot that arrow for and the market is just gonna take off This might be the month the setup is looking good in the charts So I'm gonna bring you guys the top 6.5 stocks to take a look at that could completely just take off in the month of April But before we dive into this video, this video is brought to you by Weeble Sign them down by clicking the link down in the description to deposit any amount of money And now you can receive three free stocks valid up to nine thousand dollars with those three free stocks You could keep them inside that platform and decide to use it Or you could sell those three free stocks and withdraw all of your money guys It's literally free money do not miss out on that opportunity Also, I left a link in the description to coinbase that is by far the easiest way to buy and sell cryptocurrency By using my code down in the description You can get a free $10 worth of Bitcoin and the last link is to Moomoo signing up now with Moomoo Depositing any amount of money and you can receive up to five free stocks Valid up to thirteen hundred dollars and you'll also get a bonus stock of NEO just for signing up That's one of the best offers that they had yet guys do not miss out on this free money opportunity But enough talking let's go ahead and dive straight into this video Welcome back dreamers here. We are on the first ticker symbol IIPR Now listen guys when there was the California girl rush a long time ago There were thousands of people going out there buying pickaxes buying shovels going out there to mine Gold and only a small percentage of those actually made a good wealth from finding gold out in the California gold rush so that mean a very large percentage of those people found no gold at all or cannot survive off the gold that they did find But you know who was guaranteed to make money during the California gold rush the companies that were selling those pickaxes The companies that were selling those shovels and with this first ticker symbol IIPR This is the same thing dealing with the marijuana industry now This is number one on this because as you guys know the house have just passed a marijuana Legalization bill not sure exactly what it's gonna do on the federal level, but I think on the state level that I think they're trying to Get it passed throughout the entire United States So if you want to just pick individual weed growers individual weed companies that you think might be successful They're gonna be a thousand of them that pop up I'm telling you guys it's gonna be just like the California goers Some are gonna hit and some are gonna miss but the ones that are not gonna miss is IIPR because IIPR is one of the only Reeds dealing with the marijuana industry They own the land that these growers are growing their farms their crops on and they're the only marijuana company that pays a dividend to their investors I think they have a dividend of 3.07 percent, which is awesome And over the last year they're up 5% and over the last five years they're up over 1000% now I've been investing into them all the way when they was around since 2019 So I'm up a little bit on the company I'm up 46% I only own two shares But I think it might be time and it's at a great price for me to go ahead and pick up a couple of shares because once it becomes Whether you like it or not it's gonna become legal sooner or later Maybe not this year maybe not next year, but over the next five ten years It's gonna become legal on a federal level the government level the state level is gonna become completely legal And if I'm getting in now on IIPR, this could be a pretty good one to buy over the last year The all-time low was around one hundred and sixty six dollars in the all-time high of it was around 283 dollars right now is that two hundred dollars you could get in at a good price of around two hundred dollars $180 and ride that on up to a good sale price of around $250 for a pretty large sum of a percentage in profit guys So that's the first one I'm gonna bring you guys make sure that you stay throughout the entire video because I'm gonna do a live technical Analysis on one of the stocks just so you can see how You could pick my brain on how I'm picking these stocks the second company is NVIDIA tickets of the NVDA over the last year They're up 92% now over the last three months They are down 10% so it might be a good time for us to go ahead and buy the dip now Why I'm putting NVIDIA on this list even though they're down the last three months is because yes I am catching them on sale and they have just announced that they're going to start to reduce the price of their GPUs Their GPUs are soon to become more in stock and that should scare away some of the scalpers That has just been buying all of the GPUs all of the graphics cards and graphics cards are used to mine Cryptocurrency guys, that's why they are so popular So as long as crypto currencies in the boom NVIDIA is going to do well because people are going to continue to buy that Graphics card driving up the price But now there I think that they announced that they're going to be able to produce more of their cards at a fair MSRP price So more everyday buyers would be able to come in and buy up their graphics card NVIDIA is definitely on my list as you guys can see I am already up 169% on NVIDIA and they're up what 92% of years I've been in on NVIDIA for a while now I do have more of their shares in my Weibo account, but over here on my Ribbon Hood account I only have 1.2 shares, but there's nothing wrong with dollar costing averaging into the market Which leads me to my third pick, which is Apple ticker symbol at APL Let's go ahead and pull up Apple now Apple now Apple is an absolute amazing company over the last five years They're they're the the boring slow-growing company that Rally takes dips and when they take a dip a lot of people buy up their shares on sale Now Apple over the last five years to up 400% now over the last six years Apple has acquired over 100 different companies that mean if somebody come up with some technology Apple's gonna buy that and they also do share buybacks every year with Apple and they have so much cash on hand that They pretty much can buy any other major company out there if they wanted to Apple is a major giant inside of the tech industry inside of the stock world So this is the nice stable company that I know is gonna grow 5% 6% every single year I'll perform the stock market to where to where I could dollar cost averaging on Apple maybe buy a share every week Maybe five shares every month just dollar cost averaging on Apple this one I'm going to say every single time when I do an update video. I absolutely love this company I think they're gonna do big things in the future and they're very safe because they have so much cash on hand They do share buybacks. They do stock splits and they acquire any other company that will give them a challenge in the future So that's stock number three Apple. Alright guys, so for the rest of the 3.3 stocks I'm gonna go ahead and pull up the trading charts Just so I could show you guys exactly what I see inside the market and why I think these companies are gonna do amazing in the month of April but if you guys are interested on seeing every single one of my swing trades I'm gonna leave a link down in the comment section that'll take you to my patreon the patreon to take you to the Discord inside of the discord. I post every single time I buy and sell stocks I post all of my swing trades my technical analysis that you guys are going to see inside of this video Also, it's a awesome community of traders in there with a whole bunch of knowledge all in one place So if you want all of that knowledge inside the stock market all in one place go ahead and join the discord The members in there are absolutely amazing I also have pro-day traders inside of the discord where they post every single one of that option trades Monday through Friday where people are finding a lot of success option trading inside the stock market paying attention to the Pro traders and seeing how they set up their charts and I sell options and I post them all in there So we could generate passive income so that sound like a community that you guys want to be a part of so go Here and check out that link down in the comment section to take you to my patreon All right guys So just for a quick example on how I set up my charts here We are on Disney now as you guys can see I have posted this inside the discord that the MACD was about to cross And if it crossed why it was in our buy zone then it could go ahead and start to recover And we got and we could have had an amazing little swing trade. So this is one to train swing trace I'm showing you guys on the MACD that we circle right here though as I was in it was in our buy zone That's three out of three. So when we come back over I did not change anything on the chart He came to our buy zone the MACD cross in the RS I start to pull back up and we could have had a quick gain of Of around let's say around here up to a hundred and forty four dollars So around a twelve percent gain just a matter of a week guys So quick setups like this is what I like to see inside the market So if we take a quick look at square took a simple SQ or block. All right So this is another one that we have posted inside of the discord So if we take a look at this, I absolutely love block I love the CEO now block has been on a downtrend for a while guys ever since their last earning with ports Which was in the negatives was shot them down and they stayed true to this downtrend line and Eventually we it had broke the downtrend line because they had a pretty good earnings report It shot up it pulled back to our buy zone and the shot back up to the green MA line And it's pulling back to our support zone right in here Now we're gonna play very close attention to the MACD over the next couple of days and to the RS I but right now squirts in a very good place if it starts to trend above the green MA line right here and holds true above the green MA line and the MACD starts to show Good strength with along with the RS. I we are looking for some massive games right here guys Even if we get in right here to swing trade it all the way back up to the 50 ma that is a profit of around 24 percent guys So this setup inside of so this setup for April is looking pretty nice I'm not saying that's gonna turn out exactly how we wanted to turn out It could pull all the way back to our buys on again to where we buy a couple of shares We buy a couple more shares at a hundred dollars underneath the hundred dollars We keep on buying shares but square in the future now you guys know I'm a firm believer of buying companies that we actually use I know I have yet to be to a vent to where vendors food trucks Cossession stands are not using squares in order to make to accept payments So I see them growing in the future. I'm a full believer in that CEO He knows how to grow a company to a trillion dollar market cap and he's gonna do it with block So I'm gonna keep everyone updating inside the discord on when it's a good time to enter this trade on square So I'm gonna go ahead and set up some alerts on that. The next one is Facebook. This one is absolutely One of the markets that has been beaten down by a bad earnings report it one time It was all the way up to three hundred and twenty three dollars and the earnings report dropped it all the way down to 245 dollars in just one day and it continued to pull back all the way through our buy zones We DCA right here. We dollar cost average right here with dollar cost average right here And then it started to trend back up now Why I like Facebook is because because in 2021 I had over 50 billion dollars in company share buybacks And in the second half of 2021 33 billion dollars was of that 50 billion dollars So so with less shares out there the buyback is gonna really start to show in Q1 and Q2 for Facebook So right now at a price any price under 250 dollars I see Facebook at the buy and with their buybacks that they did in 2021 We should start to reflect in Q1 and Q2 maybe Q3 of 2022 Right now is a pretty good time to go ahead and pick up pick up some shares of Facebook under $230 and the last stock stock number six. I'm gonna go ahead and do a lot of market analysis on them Very quick one that they alright, so this is the four-hour chart and this is company Alibaba I took a symbol BA BA and they have absolutely been getting beat down over the last couple of months over the last year because of some Some legal issues that they begin into it's a pretty good company But guys they have been getting beat down and it's on the downtrend right now It's at the top of the downtrend line. So let's just go ahead and draw out this channel There we go. So it's at the bottom of the channel top of the channel bottom top bottom top bottom top So it's just been riding this wave and right now it's at the top of the channel Now I believe that once it breaks above the top of this channel in this green EMA line start to point up that would be a good indicator that this company could start to recover very very soon Once it starts to trend above the green EMA line and in this green EMA line start to point up This could be a major swing trade for us now. Let's pull out the Fibonacci sequence. This is just remember guys This is a quick one. I'll post the full one inside of the discord. Here we go Now a good time would be to get in is above the green EMA if you want to be patient You can buy inside the golden zone. This is the golden zone that we buy inside So anywhere from $168 to $195 that would be a good opportunity to get in That would be a good opportunity to dollar cost average But if you guys want to ride this way from here and sell inside of the golden zone Let's pull out the measuring tool you want to get in around here and sell at the top of the golden zone That is a profit of 53% guys and this is tickle symbol B. A B a Ali Baba. So there we go guys Let's bring up stock point five now. This is a collective for stocks. This is Google they're having a 20 to one stock split Amazon they're having a 21 stock split and even though Tesla is super overpriced right now at around $1,000 at the recording of this video. They have announcements of Thinking about a stock split in to also pay dividends to their investors So if they do announce that they're having a stock split, I'm going to put these three As point five because usually when technology companies have stocks split especially a 20 to one stock split They usually outperform the stock market by a significant amount over the next 365 days we have already been dollar cost average again on Google inside of the discord We're going to start dollar cost average again on Amazon next just so that we can get those shares from when it had the 21 one stock split we will be ready. Yeah guys If you're looking for just historical data that company a does this when company a has a stock split No matter what company it is It usually outputs points to stocks market and that is based off historical data since the stock market been around guys So you don't have to just take risks. You can look at statistics and invest that way So yes, that is my top six point five stocks to look at in the month of April That could just completely take off in the future guys Remember if you want to be a part of the discord that link is down in the comment section Don't forget to go down to the comment section as well and drop a couple stocks that you guys Think is going to do very very well in the month of April any news that I might have missed any Super major news that I might have missed. I learned from you guys down in the comment section So go ahead drop down to the comment section and let me know what companies are you picking up in the month of April Don't forget to pick up your three free stocks. We will guys is free money all those links down in the description It's free money. Do not miss out on that opportunity. This will help your small account grow fast Just fight just by getting free money guys, but other than that, I'm Zeke bring you to dream grand show and I'm out. Peace