My name is Mark Hughes, and I'm the executive director of the Vermont Racial Justice Alliance. So we've been doing work in the state here for a number of years, racial justice work. Sweet, sweet. First question. What do you guys do? What do we do? Well, we do a lot of stuff. So where the racial justice alliance came from was back in 2014, at the death of Michael Brown, what I decided to do was start a kind of like a political action group to address policing in Vermont. So as a result of a lot of the work that we did there, what was created was this panel called the Racial Disparities in the Criminal and Juvenile Justice System Advisory Panel, and that work led to the creation of the Racial Equity Executive Director's Office and Panel at the statewide level. And from that point kind of pivoted into starting this other organization as a result of the momentum from the coalition work. And we started here in the city of Burlington in some of the work we've done in Burlington was to actually structure, we pitched the racial equity inclusion belonging department in Burlington, as well as the standing committee. In addition to that, there's a lot of work we did over the last couple of years in terms of driving policy here in Burlington, surrounding racial equity and also policing. Now the work of the alliance itself, some of it has to do with community engagement and support, helping black and brown folks where they are in the community, some of it has to do with outreach and education, teaching folks about systemic racism, the root causes impacts as well as some of the solutions. Some of it has to do with cultural empowerment, teaching folks and commemorating and celebrating our rich history, our culture, our contribution, our power. And again, some of it also has to do with the work that we do surrounding policy.  The most challenging. You know, I think in doing the work, as far as working in our communities and working with our people and just trying to make things better for all of us, I think some of the most challenging work, quite honestly, is just trying to figure out ways and methods for us to work together in our communities. One example is, I know there's been historically some deeply rooted divisions amongst indigenous African-American and refugee resettlement communities right here in the city of Burlington. There's a lot of challenges there because there's a lot of historical precedence on why folks are not talking to each other and folks are not working together. Some of it is cultural. Some of it has to do with our division just as a result of the role of the USCRI and may the ALV have played. And some of it has to do with challenges that some of us are just responding to things that we've been taught historically. So bringing our community together by far is the biggest challenge, I think that we have. And that's the one that I think we all need to be up to. Sweet. And since the kind of like your target is to make a change within the community, do you feel like you guys haven't been able to actually do that? Or is it just like a work in progress, you know? Like ever since you started back in 2014? Yeah, ever since, that's a great question. And I think part of it has to, the part of the answer, and I'm kind of laughing to myself is that quite often I have to remind myself that not only is it a journey, but it's, you know, and what I mean by that is that, you know, as far as the work that we're doing in organizations like us, there was organizations like us before. There are, you know, 10 years ago, 50 years ago, 100 years ago in the United States. This work, y'all will be doing some of this work when I'm gone. I'm, you know, getting up there. I'm like almost 60 years old, right? So, and y'all kids will probably be doing some of this work. And it's kind of like some people say, you know, we gotta keep moving the needle. And unfortunately what we're seeing is it's a little bit less like a needle and it's more like a pendulum, if you know what I mean. Because it seems like sometimes things are up and sometimes things are down, but we always, you know, we always gotta have folks that are up for the fight, which is why I appreciate so much, y'all brothers, you know, taking the time out and learning what you're learning and just asking all the tough questions. And it's my hope that, you know, as we march on, you know, through time, as we march on, that it'll be you and people like you and your kids that pick the torch up and keep it moving. But it's a journey. Sure. What are we going to do? Well, to kind of get what we're trying to understand, like you said earlier, is the equivalent of, like the dollar value when it comes to us Black people. Making less, yeah. Making less and like how kind of that works. Yeah, getting like a stone more. Yeah, and you know, and one of the things that I read in the email that came over was, is that the shock and astonishment that y'all had, you were like, what?  Let's just call it wealth inequity in the United States of America. And I'm talking about racial inequities as it pertains to wealth. One of the ways in which I'm often qualifying is, this whole idea of generational wealth.   And what, specifically what we see is, in the United States of America, the median, and that doesn't mean average, that's more like, you know, just, well, you guys know median, you're seniors and juniors, right? But the median wealth of a black family in the United States is one-thirteenth, one-thirteenth of that, of the median wealth of a white family in the United States of America. And widening, this is all post-COVID. Now, when you think about that wealth in America, in that disparity, if you really think about that, you can't really fix that with five lifetimes of hard work. You cannot close that gap. We're talking about median wealth. So you have to ask yourself, where did that come from? And I think that's really what you guys are kind of like, right over the target on, is where did this come from? How could this be? And I think that, you know, we have to look at, we have to look at the history of the nation in order to really understand that, to really get our heads around, we have to look at the history of slavery in the United States of America. But not just stopping at slavery, also taking a closer look at what came after slavery and what things happened in the United States that continued to create processes or policies that ensured that black people in the United States did not have the ability to generate wealth or generational wealth. And in fact, black people were actually not just oppressed or excluded, but also exploited after slavery.  Whereas it was much, much more complicated than that. And even after the 13th Amendment, what we find is that, you know, with the 13th Amendment, there was a loophole or a exception clause in the 13th Amendment which stated that except for the punishment of a duly convicted crime, which opened the gate up for this thing that we call convict policing, which enabled states to create laws to criminalize poverty and to criminalize black behavior and also laws to create segregation, to ensure that white folks could maintain property, maintain wealth.  You know, if we're talking about state sanction, in other words, the government made laws. The United States government, even a constitution of the United States, but moreover, the government itself making laws that just basically ensured that wealth would be transferred to white and it would be retained or held back from blacks. Even you hear some of the most common stories is the redlining, that is to create restricted zones in neighborhoods and restricted covenants and selling homes. But very little has ever talked about the 270 million acres of land that was given to only white people during the Homestead Act in the 1800s. The fact that the Social Security Act, as it was signed, the new deal that we learned so much about and even the GI bill, who that veterans enjoyed and appreciated that enabled them to create generational wealth by buying homes and then taking the equity in those homes and passing it down to their children, enabling them to go to college and so forth, all of this stuff played into the widening and there are still many systems in place today. It would probably surprise you to know that we're in the middle of a constitutional amendment here in Vermont where testimony will be taken to amend our constitution Thursday of this week to ensure that slavery is prohibited in our constitution in this state because there are three exception clauses in our constitution in the state of Vermont that have always been allowed for slavery under the age of 21 at a person's own contempt and also for the punishment for our debt fines and the like. In our constitution predates the constitution of the United States and actually informs the language in the constitution that permitted slavery, that also permitted slavery in the 13th Amendment. Now, many would say, and I got a short video to show you in a little bit, but many would say that how could this possibly be? Here we are in 2022, and you're talking about something that happened in 1865. Those are tough questions to ask, but when we begin to lay this thing out and begin to look at it, and as we look in the areas of housing across the state, education, I'll use education, I'll take a little bit of a deep dive into education because you guys are students, but the disproportionate impact of disciplinary actions against students of color in schools as well as what we've sought to become the school-to-prison pipeline, the unfair treatment of black and brown kids in our schools, which I'm sure you have witnessed, and then you get into Employment Health Services Act, the Economic Development Transportation. When you look at those data and we have them on our website and there are many who have began to collect these data, then every single instance what we see is that black and brown folks are disproportionately and adversely impacted when it comes to the outcomes of each one of these, every single one, to include the criminal justice system. So it really is about economics and I'll come back to you for another question, but I would just say that even with the criminal justice system, as I told you previously, from the onset, up to prior to 1865, with slave tension, but also beyond that period with convict leasing, the law enforcement apparatus played a huge component in incarcerating and criminalized power, because if you create poverty and the vast majority of folks at that time if they're demographic was poor, then de facto what you're doing is you're creating laws that affect black people more than they do like people proportionately. So this has lingered and what I was getting at with the numbers is simply that you can see it across all systems. If we go and we take a true look at the history of the nation, we can understand how that connects. And if we understand the definition of systemic racism, then we start to be able to put this puzzle together and understand why it is that we're seeing this huge disparity economically and the impact that it has on every single one of these systems. Oh, that's a lot to take in. Yeah, I think I maybe gave you a little bit too much, but we'll come back to it because hopefully we'll get a chance to catch up as well offline. I did have a short video for you because what I'm holding in my hand right now is this is a report from the Human Rights Council of the United Nations. This is a report from the High Commissioner. And I just wanted to share something just about what she had to say about this very same subject, just from a different angle. But I think it pretty much takes you to the same place. Hold on while I get this up for you. I just wanna make sure that I'm sharing the volume as well. So listen, as she speaks, and this was just last year, and we can talk more about it when she completes. This is a moment of clarity. It is also a testament to the courage and perseverance of George Floyd's family and many others in calling for justice. As the jury recognized, the evidence in this case was crystal clear. Any other result will have been a travesty of justice. But for countless other victims of African descent and their families, in the United States and throughout the world, the fight for justice goes on. The battle to get cases of excessive force or killing by police before the court that alone win them is far from over. This case has also helped reveal, perhaps more clearly than ever before, how much remains to be done to revert the tide of systemic racism that permeates the lives of people of African descent. Now is the time to critically examine the context in which George Floyd's killing took place by revisiting the past and examining its toxic traces in today's society. The entrenched legacy of discriminatory policies and systems, including the legacy of enslavement and transatlantic trade and the impact of colonialism must be decidedly abrooded in order to achieve racial justice and equality. Is there not? The verdict in this case will just be a passing moment when the stars align for justice rather than a true turning point. Oh, wow. Well, there you saw the high commission of the Human Rights Council of the United Nations. I told you what I was holding in my hand was a report, and this report is probably 25 pages. And it goes through all of so much about the observations that the United Nations have made on the treatment of African-Americans, Americans of African descent here in the United States and their expectations on their responses. So what we're dealing with here is we're dealing with something that is entrenched as the high commissioners said. And you see this manifest in so many different ways, but we always have to remember that it really started with the genocide, it started with slavery, and it was all intended for economics. For economics, it was all about making money. The whole thing was the false narratives that were created to support and rationalize the inhumane treatment of black folks here in the United States. It was necessary to perpetuate what it is that even continues to play out in some different ways to this very day. And what we see is now is we see it, what you see more clearly now than ever is it's manifested itself. It has manifested itself economically. Well, it started economically, I shouldn't say it manifested itself, but that's how it started and that's what you're actually seeing. You've probably seen it play out across housing and education and employment. You start to look at it. So yeah, lots going on here, lots to take in and we've got some class and some outreach and education that we're given in the communities and in fact, we're gonna be doing one on Thursday. We're gonna be teaching about this, the Abali slavery piece. And then we also have an economic empowerment piece that goes with it because there's other policy that we're pushing at the statewide level to attempt to begin to compensate for some of these economic disparities that are just even here in the state. My other question is that, since you're talking about the teaching of the book, are you guys planning on teaching the students like the school or something like that? Absolutely, the interesting you say that because I'm excited. First of all, I wanna get educated, okay? So, I've signed up for some Swahili classes that I'm gonna be taking on next week. I'm hoping to be able to get there. I got it. First, I gotta get educated. The other thing too is with my brother's keeper and y'all folks from the school, whoever is out there who's interested in learning more and also just kind of getting together and talking about it because we don't talk enough. We just don't hang out and just say, well, what about this thing and just wrestle with it? There are a lot of people, they just like the, most people will prefer, or let's just not talk about it at all. Or if some people say it was such a big problem, what can we possibly do about it and just choose not to have a conversation about it instead. But yeah, I'm of the opinion now with the Richard Kemp Center that has opened here directly across the street from the Community Health Center of Burlington on Riverside. It used to be the SAM furniture store there. You remember that? Right there on Riverside. So that is one of our initiatives and that's going to be a place not just where we can go because just think about this. If what I'm saying is true, and the reason why I say if is because y'all need to go take a look at it for yourself and make your mind up as to whether or not you believe what I'm telling you because people, you know you have to know these things. People will tell you anything. Right, right.  But if it is true, and I believe it is, in all of our, you know, we have, you know, volumes of data on our site that indicates disparities across all fronts in our history, not your books in school, but if you go and take a look and start looking through the internet and doing your own research on the history of the United States and reading some other books that are out there and there are many, start to put it together, then you'll, you know, I'm hopeful, I'm optimistic that you'll see it. But at the point I'm making though is that if this is true, then this means that at the same time, you brothers as black men, okay, at the same time that you are being dealt unfairness from housing, you're getting the same thing on the education front, an unfair outcome.  And that is just another factor, another indicator, if you will, there are many, but all of this stuff is happening, it's coming at you, it's coming at us, all of the time, every day at the same time. So that's the pressure that we live under as being black and America, and it's true. It's a difficult thing to navigate and it's hard to, look, it took me until I was in my 40s to accept it, I rejected it numerous times as a kid. You know, I'm a retired army officer and I chose to not listen to this because I didn't think it was true. But what I'm getting at here is that there needs to be a place for us. So that's what the Richard Kemp Center is about, that's not just for, you know, we're, you're gonna hear more about it soon, we're gonna be opening it up for some community discussions around some of the programming and activities that we have, but we're hopeful that when y'all come in there that you guys will figure out your own activities, we'll give some guidance to you, but we envision there be incentives of excellence, there be arts, there be triumphs, but there are activities and stuff for y'all to do over there. Say again. Sweet. We'll come check in when you guys are open. Oh yeah, well COVID right now is killing us about this, that way. But I'm just saying, I didn't mean to do that, I really didn't mean to do that, but it's hard right now, it's hard right now. But yeah, that's gonna be a huge thing for us, first time in our community where we have a Black led organization doing stuff in Black communities. So y'all, I'm really looking forward to that. The other thing is, it's even leading up to that, you know the hope is that you, the two of y'all and folks with y'all know, and everybody's not gonna be down with this. Everybody, you know, because we're not a monolith. There are some Black folks that look, this is not an issue and they're gonna keep it moving. Amen, let them keep it moving and that's fine. But there's also, you know, some folks that are like you and the thing is that we don't wanna separate people because of course we wanna keep the door open. Even folks that don't believe what we've, especially the folks who don't believe what we believe, we want to invite them, even also white people, okay? We wanna keep the door open just to be clear. But we just don't wanna, we don't wanna forget where we're starting with, what we're building from. And that is to create spaces for us to be able to have these conversations.  Maybe we can get some workforce development happening up in there, teach people how to create their own businesses. Just a bunch of stuff happening at the same time. Get a recording studio in there. Just all kinds of things to just keep it moving and also to make sure that we are there to care for one another. In every area where the system is underserving us, that'll give us a place to strategize and create ways in which we can compensate for those losses. And then the other thing is just to be able to also have a legacy where men like y'all can leave something for the youth that come behind you. So we can each one teach one and continue to move forward. For sure. That all sounds exciting. And definitely we have a lot more stuff about as like, as we continue to do this. But unfortunately we are running out of time. So I was going to give you the chance if you had any questions for us. Maybe. Yeah. I would love to ask y'all some questions. We don't have enough time. So I'll just throw a couple of them at you. Sure. What are your, I mean, I know right now that, let's see, doing your senior I think. I wrote some notes down. Yes. Okay. So what are y'all, what are y'all's plans? Where are you guys going to stay in Vermont? Is it anybody making plans for college to leave here or starting businesses? Or what are y'all going to do next? Basketball stars? I'm trying to go to college after high school at the first plan, but I don't know what. Like, I want to do that. Okay. Yeah. I'm kind of in, well, I'm in my last year of high school. So I'm kind of in the decision making process, you know, talking to my family and like figuring out what I'm interested in and what they'll tell us and stuff like that. So. Yeah. One of the things that we've been planning is just a mentor mentorship program. Right. So I've been talking to folks, you know, you know, and just talking about how we can, how we as Black men can make ourselves available to y'all. So my commitment, first of all, this is recorded, other people are going to watch this. I'll make myself available, you know, right now. And just let both of y'all know, you know, I'm at mark at VTracialJusticeAlliance.org, mark at VTracialJusticeAlliance.org. You don't have to write it down because you can watch this again. My number is<PHONE_NUMBER>,<PHONE_NUMBER>. So we have a staff, Isaac Elluci, we have Cleopas Mukaba. We also have, you probably know some of these folks or at least some of their youths because some of them have kids or have youth over in Burlington. And then we have Maya Longworth and we got a staff, what we're doing to put together some opportunities for folks to come out and hang out and do some mentoring, help folks with homework. Here's the last question that I have for you. With y'all, you know, there's a lot of stuff going on, COVID, it's crazy, it's just crazy.  I could never imagine being you with all of this stuff going on. I've never, I could never, and I thought I had it bad when I was in high school. And I'm not, this is not like a pity party because you guys are strong. But I just wanna let you know I'm praying for y'all and my heart does go out to y'all. I love y'all, you guys are amazing. You guys are amazing people. Thank you for what you're doing. But what do you need, what do you need help with most? But I mean, as far as the struggle on a daily basis, how can we help y'all, you know, just go a little bit further, do a little bit more? What do you think? I mean, school, the homework help, yeah. The tutor, the staff, tutors and stuff, yeah. Okay, so you think the homework is the biggest struggle? Yeah. I would say that as well. There's a couple of programs here and there that helps a lot. But I would say since I'm in my last year of high school, I'd say definitely decision-making, you know? Like this is the time where you have to make a decision that's pretty much gonna change your life. So just to know what is best for you and stuff like that. Like there is some guidance, some people that can talk to you for my advice. That'd be great. Yeah, like some people can help you, yeah, but making decisions, mentor or something like that. That's really helpful. And I think I can reach y'all through, is there been a transition in the leadership of the group there? No, just Megan. Okay, so I'll send a note to the email thread that we have going on. I really appreciate y'all taking the time and having a conversation with me. I mean, I'm honored, really, I'm really honored. I feel like I'm the God that's getting the opportunity here because I don't get a chance to have conversations with y'all. And I don't have any kids. I mean, I got grandkids and some of them are in the high school.  And I'm so proud of y'all that y'all are representing and that y'all, you guys are working hard and doing the right thing and digging and discovering and even saying, hey, I need some help. Those are true qualities. True qualities of real men. Real men are not John Wayne. Real men are those guys who cry, who show emotion.  Show emotion. We don't mind saying they don't know everything. Right. And we support one another and we care for one another. So I've never met either of you, but I certainly can tell you. Hopefully soon. Yeah, hopefully soon, yeah. I hope so, I hope. So in matter of fact, I told you that Kim Center is not open yet, but that's just because of COVID. If it's a small number of us, we can meet down there because we've got the chairs and all that other stuff in there. We've got what we need. We can even like watch a video or something if it's a small group of us or something like that and we really COVID protocols. I invite you down there, open that up to you. I love you guys. Love you. You guys are, to me, this is my heart. This is where everything starts to stop with y'all. I know that you guys are gonna do well. I've got your hands on straight. And thank you so much. Are you guys done with me and my dismiss? Yeah, thank you. That's right. Thank you for taking the time. Thank you and good evening to both of you.


Hey everyone, Raif Derrazy here, and this is your weekly roundup of the latest HIV news for the week of October 16th through October 22nd I know it's been a while, but here we are This is the week that I've got to cover for you and we'll try to catch up as the weeks go on from here today I'll be going through 14 articles covering topics ranging from whether HIV in the brain correlates with neurocognitive Symptoms, the need for people living with HIV to have anal cancer screening, the case of a man who has controlled HIV for 23 years after a short course of treatment COVID-19 raises the risk of CVD or cardiovascular disease in people living with HIV HIV viral rebound is rare, but possible following Mpox vaccination and more I won't be reading the articles per se But I will give you a brief summary and sometimes throw in my own opinion or commentary If you'd like to access the complete articles, all links will be available in the description box below But first a massive thank you to a few subscribers for their recent super things and donations I'm sorry if I mispronounce your name Anna-Own-Yo $60 PayPal donation. Thank you so much, Tan Anderson for your $30 super chat on my news video and the $29 super thanks on my Paul Edmunds interview All right, let's jump in number one AIDS map man controls HIV for 23 years after a short course of treatment A man diagnosed with HIV in 1998 has been effectively controlling the virus for 23 years without continuous treatment according to a study by Dutch researchers The unique case considered a functional cure or remission involved a complex initial antiretroviral therapy discontinued in 2000 after achieving viral suppression the man remained undetectable for 23 years and Genetic analyses revealed a lack of conventional protective genes, but a unique CD8 immune cell feature Provirus analysis showed viable HIV in his cells with a mutation possibly slowing replication Strong CD8 responses and slower replication Contributed to the exceptional virological control the article uses a couple terms that are common for this type of viral control In the instance where someone and never develops the viremia or a viral load that then has to be treated by ARVs, they're often called Elite controllers in the instance where they do initially develop viremia and consequently have to go on ARVs And then upon removing ARV therapy their body is able to suppress the virus on its own They're often called post treatment controllers When I bring on Michael Luella to talk about the community preferred language document We'll discuss why at least the first term elite controllers may be problematic and what the potential alternatives will be It'll be a really good discussion. There's some contentiousness going on about Some of the terms and whatnot. It's that's why it's an evolving language document and we'll cover that soon Number two abc news people with hiv at higher risk of covet re-infection says the cdc New federal data indicates that individuals with hiv face an increased risk of a re-infection with the covet 19 virus A study conducted by researchers from the centers for disease control and prevention and the chicago department of public health Found that among over 453,000 chicago residents who tested positive for covet 19 About five percent experienced re-infection Notably the re-infection rate was higher among people with hiv at 6.7 percent compared to those without hiv at 5.2 percent So comparing 6.7 to 5.2 percent people with hiv experienced covet 19 re-infection almost 29 percent more often. That's a substantial number People with hiv were more likely to have completed a primary covet vaccine series and booster at 31.8 percent Then those without hiv at only 27 percent So in spite of the increased likelihood of someone living with hiv having had their covet vaccine series and booster They were still more likely to experience covet 19 re-infection Also noteworthy is that quote those who were re-infected were more likely to be male Older and black or african-american compared to those without hiv and quote the findings emphasize the importance of tailored public health guidance and vaccination strategies for individuals with hiv to reduce the elevated risk of re-infection Number three AIDS map covet 19 raises the risk of cardiovascular disease in people with hiv A spanish study presented at the 19th european AIDS conference Reveals that individuals with hiv who contract covet 19 face a 35 higher risk of major cardiovascular events In the following year compared to those with hiv who do not get covet 19 The heightened risk was concentrated in thrombosis Heart failure and other heart disorders the study analyzing data from the ps cis hiv cohort And pad ris pat podris database Emphasize the importance of cardiovascular health and people with hiv recovering from covet 19 Urging vaccination and booster doses to mitigate the increased risk of heart disease in this population number four euro news Scotland launches britain's first anti hiv campaign in 40 years to combat stigma Scotland is witnessing the launch of the uk's first major public health campaign against hiv AIDS in four decades Initiated by the terrence higgins trust also known as tht the leading hiv charity in britain Unlike the earlier campaigns focused on risk This initiative aims to combat the lingering stigma associated with the virus despite significant progress in diagnosis treatment and prevention A recent study funded by the scottish government reveals low levels of knowledge about hiv in scotland with 46 Expressing shame about disclosing their hiv positive status The tht terrence higgins trust campaign Seeks to address these issues and educate the public about advancements in hiv understanding and treatment over the past 40 years Number five the dallas morning news prism health expands condom delivery service to include at-home hiv tests statewide Texans can now receive free at-home hiv tests through the expanded nice package program by prism health north texas Launched in 2020 the program initially offered free monthly condom deliveries Texans can choose from various packages including condoms dental dams and lubricant with an option to add an or a quick in-home test kit Amid rising sexually transmitted infection rates This initiative addresses the need for regular testing as part of prevention Each at-home test costs 25 dollars providing an accessible and private option Especially for those uncomfortable with public testing venues prism health north texas aims to combat the increasing rates of stis Particularly in designated priority areas like dallas and terrant counties the nice package program distributed over 220,000 condoms from september 2022 to august 2023 The at-home hiv test which uses a cheek swab delivers results within 20 to 40 minutes And is 92 effective at detecting hiv The initiative includes resources for treatment and support for those testing positive Emphasizing the importance of addressing hiv and stis with accessible and innovative solutions Number six aids map making pep available in the community could reduce new hiv cases in africa by 31 Making the antiretroviral regimen of tenapha vir, lemivudine and dalu tegra vir also known as tld available in the community for post-exposure prophylaxis or pep After condomless sex without a prescription could reduce hiv acquisition by 31 Over 20 years in african countries according to a modeling study published in lancet global health Currently pep is not widely available in community settings in eastern and southern africa The model used tld a preferred first line treatment regimen in most african countries to assess the potential impact of community access to pep The results showed increased uptake and a 31 decline in hiv incidents over 20 years with cost-effective outcomes While the analysis suggests feasibility Unanswered questions about community tld including its acceptability and potential drawbacks Highlight the need for pilot implementation studies The researchers emphasize the regulatory barriers to access and recommend exploring the distribution of pep packs in public places to enhance accessibility Number seven business wire gilead sciences announces new clinical trial in europe to assess Lenocapavir for hiv prevention as part of landmark purpose program Gilead sciences has initiated purpose five the first phase two clinical trial to evaluate An investigational long-acting hiv prevention option in europe The study will assess the persistence of lenocapavir compared with m tricidabine tenapha vir Disaproxial fumarate also known as f tdf and people who may benefit from pre-exposure prophylaxis prep And who are not currently taking prep? Lenocapavir is a first in class hiv capsid inhibitor administered as a twice yearly Subcutaneous or below the skin injection. It is currently approved for hiv treatment in persons with multi drug resistant hiv one infection And is also under investigation for hiv prevention The trial focuses on recruiting participants from groups across france and the united kingdom that are disproportionately affected by hiv And often underrepresented in clinical trials Number eight pause calm sun lenka remains active against drug resistant hiv Results from the capella trial reveal that sun lenka Also known as lenocapavir The first hiv capsid inhibitor remains effective at two years for highly treatment experienced people with multi drug resistant virus Sun lenka developed by gilead sciences was approved in december 2022 For individuals unable to maintain viral suppression on their current antiretroviral regimen The long-acting drug disrupts hiv's capsid and can be administered just once every six months The phase two and three capella trial demonstrated sustained rates of verologic suppression and clinically meaningful increases in cd4 counts at 104 weeks sun lenka's unique mechanism of action makes it effective against hiv that has developed resistance to other medications Number nine cdc expanding prep coverage in the united states to achieve ehe goals The cdc has released preliminary data showing that in 2022 more than one third Of people in the us who could benefit from pre-exposure prophylaxis had been prescribed it for the first time This marks progress in hiv prevention efforts aligning with the goals of the ending the hiv epidemic in the us initiative Overall 36 percent of the 1.2 million people who could benefit from prep were prescribed it in 2022 Compared to 23 percent in 2019. However disparities persist with 94 percent of white individuals benefiting from prep compared to 13 percent of black and 24 percent of hispanic latino individuals Efforts must focus on equitable access to hiv testing treatment and prevention to address these disparities and end the hiv epidemic Number 10 the body pro hiv viremia is rare But possible following mpox vaccination italian study finds a study conducted in italy has found that while rare Viral blips and failures can occur after people living with hiv are vaccinated against mpox the study investigated 187 virally suppressed people living with hiv who received the modified vaccine Ankara Bavarian Nordic vaccine Six viral blips and three virologic failures were observed with two failures occurring after the second vaccine dose The study suggests that close monitoring of viral load after mpox vaccination Is essential to identify and treat rare cases of antiretroviral treatment failure appropriately The study's authors recommend administering the vaccine at the person's place of hiv care for easier monitoring Quote blips or failure were also more common in people living with hiv with lower cd4 cd8 ratios And a previous AIDS related event than those without such factors and quote Number 11 the body pro Sero conversion while using depyverine ring does not lead to drug resistant hiv in african study So just so you know sero conversion means when you go from someone who is not living with hiv to someone who is living with hiv That is sero conversion Research has found that the depyverine vaginal ring approved for pre-exposure prophylaxis in sub-saharan africa Is safe and effective in preventing hiv sero conversions Without leading to drug resistant hiv when the virus is acquired while using the ring in an open label study samples from 38 women who sero converted during the study were sequenced and none showed mutations indicating resistance to non-nucleoside transcriptase inhibitors or nn rti's the study emphasizes the continuing To use the depyverine ring after sero conversion did not increase the risk of developing resistance The findings support the safety and effectiveness of the depyverine ring in preventing hiv transmission So this is of some concern for people who are on some form of prep that perhaps say as an example someone Acquired the hiv virus and they're still in that window period where if they were to take an hiv test It would come up negative So they go to the doctor they've acquired hiv But nobody knows the test comes up negative and the doctor says here. I'll put you on prep to help you Keep you safe and prevent you from getting hiv So this person is now living with hiv unbeknownst to that person unbeknownst to the doctor And now they're on prep the concern is for someone who is in that position that while on taking prep that they will That will encourage the virus to develop drug resistance because as we know prep Isn't able to fight the virus in people who are living with hiv. It's only prevention measure if Someone like myself were to take prep. It would be of no good. And in fact, it might be Negative consequence because it might encourage my virus to develop a resistance to say if I was taking trivada It would develop resistance to trivada For someone living with hiv trivada would have to be taken in combination with another drug That's why we have combination therapies for people living with hiv So the depivering ring is a form of prep and what they're saying that this study found is that certain women had Acquired hiv. We're now living with hiv While they were also using the depivering ring as prep. So there's concern. Would it develop Resistance in the hiv virus and fortunately in the study at least it showed that no one Had developed any kind of mutations resistance to the depivering ring. That's a great sign And so now hopefully that means we can have less concern over these types of situations popping up when it comes to the Depivering ring number 13 aids map hiv in the brain. Does it correlate with neurocognitive symptoms? Swiss researchers have explored the presence of hiv in cerebrospinal fluid CSF and its correlation with neurocognitive symptoms. The study published in the journal of acquired immunodeficiency syndromes involved 288 participants with neurocognitive symptoms who underwent lumbar puncture. That is When they poke you in the spine They found viral escape in csf in 25 participants But there was no clear link between its presence and symptoms The study questioned the justification of invasive lumbar puncture for routine clinical care as the correlation between viral escape And neurocognitive symptoms in undetectable individuals on treatment remains uncertain Noteworthy quote the virus analyzed from three of the participants with detectable csf Cerebrospinal fluid viral load was resistant to the treatment They were taking at the time of the measurement while the virus in their blood had no resistance This highlights the isolated nature of the central nervous system and that some virological events may take place independently in that anatomical site and quote another part of the article states quote one area of I found this on the web now, bitch Another part of the article states quote one area of possibility that so far has been underexplored Is immune interventions for the central nervous system instead of focusing on the virus directly when already undetectable Immune responses could be improved through various brain targeted anti-inflammatories or other drugs So that the immunological environment of the csf is more favorable for and conducive to brain health I find that really interesting and I didn't know that Could occur that someone like myself could be undetectable on on treatment successful No virus of the blood and still have this active virus in the cerebrospinal fluid that has developed a resistance to my medication totally new um Learned something new every day and but the I think the the key takeaway from this study is that they Didn't see any correlation between those who had the virus in their csf and those who didn't with Neurocognitive symptoms, so that doesn't seem to be a At least on face value direct link to Neurocognitive symptoms But I'm sure that they're going to do a lot more studying of that now that they found that out number 14 nata p only half of the msm with hiv getting screened for anal cancer msm stands for men who have sex with men A retrospective study conducted by Yale school of medicine Revealed that only about half of hiv positive men who have sex with men attending an academic hiv clinic with an anal cancer screening program got screened with an anal pap test or high resolution Anoscopy through a five-year follow-up the study focused on 432 men and researchers noted that some men who have sex with men with a higher risk of anal cancer were less likely to get screened anal pap testing was also found to be blind To high-grade anal lesions not a good thing the study highlights the challenges of using anal pap as a screening test in the Real world and emphasizes the need for better screening tests and Implementation models for squamous cell carcinoma of the anus and hiv positive men who have sex with men This is another one of those things that We need to continue to have discussions about as far as comorbidities go and aging with hiv for those of us living with hiv there are certain risk factors just like this anal cancer and providing a Structured guidance to health care providers So that they can guide us As we get older to do certain things at certain junctures along our life path So maybe like every five years we get this anal cancer screening But these are all things that should be packaged together all the things that we should be concerned about neurocognitive impairment cardiovascular disease, you know hypertension, whatever it is In this case anal cancer screening So that we know Periodically the types of tests that we need to take the certain things that we need to look out for what we can do to prevent them What we can do to treat them etc etc and have it all Congregated in one place so it's not like we're like scrambling on the worldwide web to find these Things here and there and kind of try to piecemeal it together on our own. That's not right All right links to all these articles can be found in the description box below this video Be sure to like this video subscribe if you haven't already hit that bell So you get a notification every time a new video comes out and please share this with anyone who might find value in this Content that is the best way that you can help support me and this channel until next time. Cheers


What's up everybody Jason here from Jaspies case breaks and jaspies.com. So actually I'm doing a personal here for For a customer Lewis who bought in on IG Yeah, she's watching here on YouTube So we're ripping it here and the good thing is that I can record this so in case we pull a monster We can always relive it or just in case if something happens Can always rewatch it later, but yes two boxes of leaf ultimate soccer I think Lewis got here got like a nice little little soccer mixer two of these Two hit parade emerald soccer boxes, and then one footerra Football box here It's awesome. Let me quickly just put this trash down, but Anybody else wants to do in the personal If you were to die down I might fire up the IG, but but if it's we're still busy here I mean, I'll just Continue to stream on YouTube only Thank you. Let's appreciate you man. Good luck So just five autographs plus one memorabilia card. I don't think I've actually ripped this product this years Look forward to it And forgive me on some of my pronunciations here for some soccer. All right, we got Ollie Watkins Looks like number three out of three Ultimate signatures we have a three out of three of Of Tawana Shura, I'm sorry Then we got a one-of-one. I can't even see the names on that bro. How am I supposed to see that of Omari Jiro Hutchinson One of one we'll take it. We got a Ryan Finnegan to 10 leave XRC rookie That's a little easier to read and we got Freddy from out of 25 Jumper and then last one here is a six-way rally. Wow. Nice one here team Brazil Palais Roberto Carlos Diago Silva Ronaldo Vinny jr. And Neymar jr. Pretty nice pretty nice It's a cool little one right there. Yeah, there's the first box Let's go to the next one. This one does have some Lionel Messi's in here. So Something we're kind of trying to chase here. All right. We got a one out of two of Will Dixon Looks like place for Manchester City, right? We got Tyreek writes To 18 We have a six out of eight Harvey Vale We have a Kamarai Sawyer to 10 and nice one right here Little Danny Elvis to 18 and then last one here is actually a pretty cool How about a little piece of relic of Ken Griffey jr. With Derek Jeter? Lionel Messi and Ronaldo Christiano Ronaldo six out of ten of course authenticated To be a Piece of the game use memorabilia of these four athletes here. It's pretty awesome Four goats right there. All right, cool Now this hip-rate emerald should be a lot nicer in that sense that it's a Emerald edition of hip-rate and obviously I've seen some of the bigger hits you can pull out here some really nice cards potential So let's see what we got here. Well, there we go a little messy panini instant World Cup Qatar PSA 10 that's awesome So they made these right when they won the World Cup This is actually serial number one of Those ones right there Pretty cool. Sure. That probably sells pretty well if it's in here All right, the last one here We'll go to the terror so it feels a little heavy Maybe a panini eminence soccer card. Oh It is one of those passing the torch autographs Looks like Luis Riva and Paolo Rossi for Italy. Nice. It is one of those Little old-school players. I have no idea who they are, but There you go Since Riva's team was down to test the time his place atop of Italy's career goal list may also be reserved for a long haul 1968 European champion Riva set the mark with 35 goals Rossi knew is way around the net to the star of the 1982 FIFA World Cup winning team Bagged six of his 20 career goals in the finals That's pretty sick Eminence soccer man was a super expensive product. All right. Awesome. Nice nice ones right there And now let's end off with the footerra soccer So probably one of the coolest boxes to put them in here too. Nothing else under here There so you can see them and then we'll go with this one here first. Oh, we got Jules Ederson and Joelle Filesche Numbered 60 the 20 60 that's 55 These two I believe we're not numbered We got Moises Alexandria sock Zlatan Ibrahimovic It's a cool one. Is that a one-on-one? No, that doesn't say one-on-one Then we have a vintage David Villa piece of the relic jersey right there looks like 11 out of 21 Nice. We got a gold-plated frame I think coming up Those are pretty nice Dubes Sadio Mane and Julián Alvarez Diago Silva out of 20 KDB Etter And then we got a gold-plated Kim Min Jae Feast of the jersey and again gold-plated there eight out of 12 Pretty awesome actually last two here Casemiro We have a few Hernandez heritage numbered eight out of 35 Lissandro Bastoni under 62 And then we got a talisman game use of Pavel Nevideth Looks a little old school there out of four Pavel Nevideth All right last box here Good luck, buddy. Thank you man. I appreciate it. If you also want to do more Personals right now too. Let me know I do have a two box Bowman's best that sold out, but that's a quick one and I can quickly do another personal here for you if you want All right, we got Ruben Diaz Jude Bellingham Rice Federico Valverde and then Gabor Martinelli I don't think any of these are numbered Oh, actually Jude Bellingham's number. All right, awesome Then we got a heritage droga Numbered nine out of 29 Then we got Arda Guller And last hit is going to be a honors relic game used of Immanuel um A day board Number 21 out of 25 Piece of the jersey there Yeah, they don't make too much of this Eric. It's a pretty popular release. It's kind of More like on the international side But uh, it is a fun one man. It's kind of cool to rip some of this stuff All right, thank you Lewis appreciate you man. I'm gonna top it all this right now But like I said, let me know if you want to place another order But I'll stop this video from recording so that way you do that, but thank you man. Appreciate it So again, like you know, you got these hits here You got that book a little messy Quad relic with all the goats and then a couple of these uh Leaf autographs there appreciate it man. Thank you


A more striking example should be familiar to anyone who has grown up in a Christian society. At Christmas, we may express our inner feeling for the mythological birth of a semi-divine child, even though we may not believe in the doctrine of the virgin birth of Christ, or have any kind of conscious religious faith. Unknowingly, we have fallen in with the symbolism of rebirth. This is a relic of an immensely older solstice festival which carries the hope that the fading winter landscape of the Northern Hemisphere will be renewed. For all our sophistication, we find satisfaction in this symbolic festival, just as we join with our children at Easter in the pleasant ritual of Easter eggs and Easter rabbits. But do we understand what we do, or see the connection between the story of Christ's birth, death and resurrection, and the folk symbolism of Easter? Usually we do not even care to consider such things intellectually. Yet they complement each other. Christ's crucifixion on Good Friday seems at first sight to belong to the same pattern of fertility symbolism that one finds in the rituals of such other saviors as Osiris, Tammuz and Orpheus. They too were of divine or semi-divine birth. They flourished, were killed, and were reborn. They belonged in fact to cyclic religions in which the death and rebirth of the God-king was an eternally recurring myth. But the resurrection of Christ on Easter Sunday is much less satisfying from a ritual point of view than is the symbolism of the cyclic religions. For Christ ascends to sit at the right hand of God the Father. His resurrection occurs once and for all. It is this finality of the Christian concept of the resurrection. The Christian idea of the Last Judgment has a similar closed theme that distinguishes Christianity from other God-king myths. It happened once and the ritual merely commemorates it. But this sense of finality is probably one reason why early Christians, still influenced by pre-Christian traditions, felt that Christianity needed to be supplemented by some elements of an older fertility ritual. They needed the recurring promise of rebirth, and that is what is symbolized by the egg and the rabbit of Easter. Note, concerning the finality of Christ's resurrection, Christianity is in a scatological religion, meaning it has a final end in view that becomes synonymous with the Last Judgment. Other religions in which matriarchal elements of tribal culture are preserved, for example, Orphism, are cyclical, as demonstrated by Eliade in The Myth of the Eternal Return. New York, Bollingen, Pantheon, 1954. End of note.


We're about to start the next talk right here. So I'm very happy to introduce Hanni Miel, who's going to talk a little bit about the struggles you're facing when trying to find the next capture of the flag adventure and how he is proposing to solve them. So please join me in welcoming Miel. Thanks. Yeah, so I'm going to talk about about CTF in a box. It's the story of what problems we found when playing CTFs in terms of the framework, how we tried to solve the problems. We built a prototype, tested it, and the problems that came up after that. So first, who am I? Well, I'm Miel. I am Hanni Miel on most platforms, studying computer science at Düsseldorf, and playing CTF with FlexOrela, or sometimes as a single player. And let's start with the current solutions. Because when playing CTFs, we currently have about three main platforms we play on. The most used framework currently I'm seeing is CTFD. CTFD is the first thing you find when googling for, hey, I want to host a CTF. What do I do? And the second thing is hack the box. That's another case study for another framework for hosting CTFs. But you can't use it because it's actually a closed source, so you can just play with them. And the last solution are custom frameworks. So these are frameworks used by teams. They build them themselves like at this year's CTF. So CTFD looks like this. People who may have played CTF may have seen it, because most CTFs are hosted on using CTFD. And overall, it's pretty basic. It looks a bit bootstrappy. And I'll come to what the problems are later. Hack the box. So the people who have seen it looks like this. This is the machine view. Because hack the box differentiates between machines and challenges. Challenges are like simply files thrown at you where you have to find the flag. And machines are a bit more. It's like you've got an actual machine need to find flags in the actual services running on the machine, so it's a bit more. And custom ones, like this is an image of the current CTF running at 36.3, organized by HXP. It's pretty much a CTFD, but built by their own. So what are the problems with this? Well, let's start with CTFD. There aren't actual problems, in my opinion. It's mostly static hoster for files you want the people to use for the CTF and some custom infrastructure for a scoreboard, for registration and stuff like that. So yeah, you could probably use an NGNX for that. Hack the box is kind of closed sourced. I say kind of because you can actually use it. You see how it's built up, how you spawn things. You could build it yourself. That's what we did. And the problem here we had was when playing Hack the Box, we had some reverse shells in the root of the challenges and other problems, like multiple people writing into some challenges and some files were just there that shouldn't be there. And that was really annoying sometimes, like we started a challenge and saw, oh, there's a reverse shell for getting root in root. We don't have to do anything. And they are shared challenge instances. And a problem we saw with that, that was you have multiple hundred people playing the same instance. We had the problem at Alice CTF during the camp where we also found a little problem where we could see what other people were uploading to the challenge, which kind of helped us. And we found that could be optimized. And the third problem, well, problem, it's not really a problem, are custom frameworks. You might find errors in custom frameworks allowing to get flags that aren't used to without actually solving the challenge. So it's now a ping-pong between finding problems, finding solutions, finding problems, and finding solutions. And we'll start with the solutions. The simplest solution we tried to implement for our CTF at our local hackerspace was generating single challenge instances for every player or team. This means every challenge we built was simply a Docker container, we spawned somewhere, and for everyone who wanted to play it, we spawned a new Docker container. And we first thought that it might bring a lot of overhead, but it actually didn't. We spawned multiple hundred containers and it all worked out fine. The problem with this is, if you put everything into a Docker container, Docker escapes and sandbox escapes get really useful. So it will be fatal if someone could break out of the container. And we've got solutions for the problems, of the possible solutions for the problems. You can just put everything in a VM, so the challenges are bundled in one VM or use NSJL to isolate the processes. And stuff like that is just a measure to stop the people from actually breaking out. Another solution would be to actually make it possible so that people can break out, so actually you don't want to make it possible, but you don't want the people to actually have anything from breaking out, like custom flags for custom teams. We did that by implementing our Docker containers as we implemented the challenges, so the flags get put into the Docker containers via environment variables. So when you're starting your Docker container, you just set an environment variable with your flag. And in the Docker container, you've got a little script pushing the flag to the place you want it to be, and then unsetting the environment variable and deleting everything else so there's no trace of the flag where it shouldn't be. And that worked out pretty well. So that's the Circus prototype we used, a little story for that. We had the 18th anniversary of our Hacker Space this year, and we thought we'd need a CTF for that. And in the week before, we realized, oh, it's in a week, so we quickly started building a prototype for this called it Circus, because it looks like a circus. And that's a graph showing how the containers interact with each other. And the goal with us was we wanted a place where the teams could register and get a known companion. A companion in our system was like a place where people could go and spawn an individual container because the companion spawns a VPN container and packs all the other challenge containers into that network. So people go, get the VPN config, and can access their challenges. It's really similar to how Hacker Box works. A problem with this was we've got one companion container per user or per team. And we've got N challenges that can be spawned. And if we've got N teams with N challenge computers, we get a lot of containers. What you are seeing here is just a listing of all the containers we had spawned. It was like after day one of the CTF, we had like 10 participants or so. But we had like, I think it was about 50 containers at that point, which was quite a bit. And at the end of the CTF, we had like about 120 containers up and running. So you might think, oh, a lot of containers running, people doing stuff in the containers that must cost a lot of computational power. But it actually worked out. We had set up a virtual machine with like eight cores, 16 gigs of RAM. And it always looked like nothing at all was happening. Until someone set up a crypto miner and had fun with that. So we went on a machine and said, oh, whoa, where's the load coming from? And we identified it. It was some Redis container, someone of a team set up, of me. And yeah, we had some people try weird names.  And that's a learning for everything. That doesn't work. Also, the XSS you were seeing here, that the person tried wouldn't work. So it was kind of weird. And we set up a super basic scoreboard. So as you can see, we tried building a CTF framework on our own. It kind of worked. It all was built in a few days. And it was like really shitty CTF-D. So what we want to do now is find out what we want to do and what we do not want to do. So what we wanted to do was allow people to spawn containers with their challenges. So we solved the problem of multiple people acting on one instance of a challenge. By doing this, we won't want to allow them to spawn infinite containers. Maybe some of you have played Alice CTF or Camp CTF. That was pretty fun because there was a challenge, the Nexantec DevOps challenge, where it was exactly like this. You could spawn containers or a set up for you to play in. But you had to do a proof of work. So calculate something so you couldn't just spawn challenge instances as much as you like. Another thing you might keep in mind when doing this, we had to keep in mind a lot was mount the Docker socket or don't mount the Docker socket into everything. As fun as it is to spawn Docker containers from Docker containers.   Yeah, do's and don'ts allow players to execute stuff in containers. So just having a container with some static files or so is fun. But we were like, we want to have more. And allowing people to exec stuff in containers can be a problem. But you have to limit what the people can do. And that's a thing. Allow people to do stuff but don't allow them to do too much stuff. And that worked out in our case. But as I said before, we tried it with like 10 people at our local CTF, seeing where the problems get when we put really good CTF teams on it. And if they are able to break out, it would be really interesting. So as I said, don't allow people to do stuff. Don't allow them to do too much stuff. And implement techniques so it works out. And one thing I had to keep in mind, keep in mind, keep things simple. Because during the CTF, I realized we built a lot of stuff. It was a bit over complicated and made things a bit too hard to fix. So I'd keep in mind for the future, if you're building a CTF framework, keep it as simple as possible. So if anything breaks, it's like a five-minute job to fix it. Yeah.  Create new platforms. CTF platforms are really interesting. I found a lot of topics I could work into when building this. And not at the end yet. So there are a lot of things I still need to look into. But a lot of players to play the game and limit the bad stuff. And for people thinking, why Docker? I had that in our local hackerspace. People ask me all the time, why are you using Docker? There are so many known exploits for that. Yeah, finding alternatives was like, yes, I could use the alternative, but I'm used to Docker. So I actually wanted to use Docker, and it was kind of nice. So if you know a better solution, find the solution, implement it, and try out the CTF. Another thing I wanted to say here is that while using Docker, it might be insecure if you're doing stuff. You can implement a lot of stuff securing this, like I said, implementing custom flags for teams. So if a team has got a custom flag, it can't break out of the container and just get the flag from another team because it's really team specific. And that was a thing we wanted to do with the environment variable in the challenge containers because we could start the container as we went. Yeah, so that's actually the end. That went quite fast. What I wanted to say now is that sometime next year, we want to play the Circle CTF with the platform we built, just to try it out, but in a larger scale. So if you're an active CTF player, watch CTF time, we're going to be there sometime, probably, and organize a completely new CTF with fun challenges. I've got some challenges we used for the DoF CTF with me, so if you're really interested in how this might look, how this might be different, what can be done, come to my table at Dagnebola, it's right over there, and we can talk about that. Another thing I wanted to do is if you're interested in discussing a bit of how this could be done better, or so, just drop by, that's fun. And if you've got questions, watching the live stream or so, just tweet me at honeymeal, that works out. Yeah, so that was it. So has anyone gotten any direct questions or so? Or any? Yeah, so we have around six minutes of questions left, so if you have a question in the room, come to either the right or the left microphone here, or we also do have a signal angel or relaying questions from the internet. Does the signal angel have any questions? Give me a quick sign. No, it doesn't look like any questions right now. So thanks again, Emil. You're welcome.


Go ahead and have a seat baby. Poppin' you know it's on and poppin' ooh ooh ooh ooh ooh ooh You like that young boy don't you? What you call him? Breezy? Yeah, I know all about Chris Breezy. That boy got talent. He remind me of me back in the day. Slippin' and slidein' all over the stage. I hope he's slippin' slidein' my DM one day. Damn baby, you take it in the DM too? How much extra you charge for that? Now don't forget, you gave me a Coochie coupon. Why are all men so disgusting? The human men are just as bad as the roachmen. All you can think about is sex. You're just the great women. You don't care about our dreams, goals, or ambitions. We wake up every day and have to work twice as hard just to make the same amount as you. We birth your babies, take care of you when you're sick, and we're the backbone to the society.  And chocha, don't forget the chocha.  Damn, cousin. You went from zero to a hundred real quick. Real quick?  It's so golden and beautiful. Like you. Oh, baby. This must be what heaven smells like. My mouth is watering. Mine too. We got tits in the building.  I'm just playin'. No, you ain't. Damn, did you blame us? I mean, look at him. It's so, so delicious.  Oh, man. He finally went in shock. He literally in between his three favorite things, two big brown titties, and a fresh batch of Jiffy Pop. It's the Roach and Trinity. We got to save him. Uh, no. We got to get out of here before he gets us all killed. I am too cute to die. I'm gone. Girl, you coming? I can't leave Ray. Girl, take Scrap and fly out of here before they see us. I'll meet you back home. No, I'm not leaving you. Baby, you can fly. I can't.  Go with Lauren. We'll be fine. I promise. I love you. I love you too. Now go. Hey, hey, bro.  I know.  I can't. I'm stuck. You ain't stuck. Let's go. No, for real. I'm stuck. They're big and soft. And they taste great, but they're crushing me. Wait, I got an idea. Rhonda, hold Scrap. We'll be right back. I sure love a woman who can eat.  Oh, yeah, baby.  Why don't you let me get that for you? Ow. Get in there, man. Wait, baby. Get in there. Okay, you know what? I'm out. Wait, wait, wait, wait, wait. Oh, it's above him now. Huh? Oh. Hey, what's that on your lip? Bruh. Is that shit? What the? Did he just talk? Huh? Yes. That's my girl. Just don't move. Maybe if we stay completely still and don't look at him, he won't look at us.  Hell no. Yeah, got your hands now. Oh, you better not be stuck in my carpet. What the?  Go, go, go, go, go, go, go, go, go, go, go, go. I'm scared, but I can't stop laughing. He's going to murder us. Yeah, but not the name. That lady is super strong. Did he have poop on his face? Look what we got.  Don't ever scare me like that again. Phew. You really saved the asses back there, baby. For real. Thank you. You too, Lauren. Damn, little brother. I'm so glad you're okay. And you too, little cousin. Boy, get off of me.  Everything I just went through, he better love me. Well, I love you more than anything. Thank you so much for getting him. Twice. Well, guess what you're going to get? Twice. A doggie door? Sick of him. What? Ah! Ah! Ah! Why are you coming out?


Metal scaffolds made from biodegradable materials offer great promise for use in hard tissue regeneration due to their excellent mechanical properties and ability to degrade over time. Computational methods can be used to optimize the porosity of these scaffolds, allowing them to closely match the mechanical properties of human bones while still being able to degrade in the body. This article was authored by AHUZOP, AA Baki, NA Shaharom, and others.