So, y gweithio. Thank you very much for the invitation. I very much enjoyed this meeting. For those of you who don't know me, which I think is pretty much everyone, I'm predominantly a researcher. My group identifies genes that predispose cancer. I'm also a clinical geneticist and I run the cancer genetic service at the Roym Marsden Hospital. And I'm really going to speak to that today. We are particularly passionate about trying to realise a wnaeth eich cyfnodau wahanol mewn cyfnodau newydd i gynhyrchu eu ddweud o bobl o'u cyfrifiadau i ddweud i'r llyfr y lleidion llawm. Felly, i wnaeth eu cyfrifiadau yma, rwy'n amdano i'r cyfrifiadau yn y cyfrifiadau yma, yna gydag hwnnw ymddangosiaethau oherwydd mae'r cyfrifiadau cyfrifiadau yn ydych chi'n gweld i'r cyfrifiadau. Felly, rwy'n amser, felly rwy'n gydag o'r cyfrifiadau i ddweud i'r clywed. Felly, dyma'r rheoli y gallwn gweld, sy'n gweld, gweld yn ym Oaf fynd yn dod nifer 15 yno, sy'n gwybod y rhain oedd, a phrofiadau yng Nghymru sydd wedi gynnig o hyd o gwybod o fwy'r fwy yr ysgolig clwnifidol gyda'r llagneu ac oedd cyntaf iddyn ni'n gwybod dim ydych chi'n ffordd i'w gwaith y maen nhw'n cweithio o'r sefyllfa'r höllunol yn y rhagor a'r bais抽 wrth gofyn i'r holl. A'r adnod ein bod ydsigol gyda cyfrifau a sír a'r ddysgwys ymddangos yn y dyfodol. Rydyn ni'n credu'r graff yw'r gweithio'r ysgolodio'i gael ar yr unrhyw sydd wedi'u cymunedol yn cael ei ddweud o'r droswm o'r gwneud hwnnw, yma'r ddweud yw ddweud yma eich 24 cymrydau sy'n ei ddweud ar gyfer gyfwilol. Mae'r droswm wedi'u cyfrifio'r gyfrifio'r ddweud, yn cael esganol o'r ddweud o'r ddweud o'r cyfrifio'r ddweud, y rhaid i'r gen i rywun o'r tudwg. Rwy'n gallu Llywodraeth i'r rhaid, oes e'ch cynnig, ond bydd am y 내wn y rhaid, a buddwyl sydd sy'n rhaid i'siolio, i'r rhaid o microbiol rhaid i'r run i'r mynd i'r bwyd. Maen nhw'n mynd i'r rhaid i'r rhysgu honno 10 o 15 o'r ffordd, rhaid i'r rhysgu o arall o dwyled o'r llifn honno gynol. Y ddefnyddio gynhyrchu hefyd yn ystod ar hyn o'ch mysensio ffairianysau i'r busau. Rydw i'n debyg ar gyfer y lliwyddiadau i'r rhaglen ychydig. Y dyfodillrwy'r gynhyrchu hefyd yn ddoddogf yn gweithio ar gyfer ond y cysyllt ddwych yn rhan, ychydig ar gyfer y gynhyrchu ddwych yn rhan o'r 2,000 o gynhyrchu ddwych yn llunio ar gyfer ond y cyflnwys. When you do that kind of experiment for this type of gene, there's a very clear signal between your cases and controls with respect to truncating mutations. But when you look at the miss-sense mutations, the data is really quite interesting. So you will always see multiple, rare, usually singleton, miss-sense mutations that are only present in your cases. These are just the type of miss-sense variants that are called V攝s, or in gene discovery papers where controls are not analyzed, be cyfnodd yn fwy oedd yn fathogennu fel ydych chi'n meddwl i gydag i'w cwysbeth fyddwch. Ond, ond, y gallu gwladwch y ddweud o ddweud y gydag, ac ond sy'n gydag i ddweud i'w cyfnodd a dwi'n meddwl i'r ddweud o ddweud o'r ddweud mae'r ddweud y ddweudio, mae'r ddweud o ddweud o ddweud o'r ddweud o ddweud o'r ddweud.  Mae'n ddysgu'n gwybod fwy o'r wladau. O'n fwy o'n fwy o'n fwy o'r bwysig o'r cyfrifoedd? Y ffordd, mae'n cyd-ddefnyddio am ymddîm gallu tynnu … … a'r ddrifogolod. So, mae'n trefwg hynny yn gweithio'n ddylu o hyd … … ac mae'n ddifogol ar yMyth-Centh ac ar gweithio'n ddylu ac … … mae'n ddifogol ar gyfer araf amddîm hynny a ddifogol gweithio'n ddylu. Mae'n ddifogol ar gyfer ar gyfer tyg amddym hynny … … oeddi'r ddifogol ar gyfer gweithio gweithio gweithio gweithio. is often assumed to be the same as pathogenic, just isn't. It's incredibly difficult to pick out disease-causing mis-sense mutations even in genes which we know cause disease. I think the bottom line is that buses should be considered and we consider them as innocent until proven guilty. I think that everybody does know that when you talk about it, but actually instinctively a lot of people, even the most expensive fields, are actually when they see those variants, they actually manage them as guilty until proven innocent. I think that that's a problem. With respect to clinical utility, we're not using the GWAS common variants and I don't think that we'll be doing that in a meaningful way anytime soon. With respect to these intermediate penetrance genes, I think once sequencing makes that cheap and quick, we will be able to use them. But BRCA 1 and 2 is clinically usable and in many ways offers all that you could hope for from a disease gene. I think with respect to unaffected women, people are very on top of this and they understand this, these women are at high risk of breast cancer, ovarian cancer, we give them increased surveillance. They will often have their ovaries removed after completing their family and many of them will also have bilateral mastectomies. I think surprisingly it's underappreciated just how important and how helpful it is to know the BRCA status in somebody who has cancer. If you have breast cancer and you're BRCA positive, you're at high risk of having bilateral breast cancer, you're at high risk of having ovarian cancer, increasingly there are genetic tailored treatments such as PARP inhibitors which are close to being in widespread use that are tailored to that genetic defect. This is making a sizeable contribution to this cancer incidence. So if you take unselected ovarian cancer just walking into the clinic, over 10% of those will have a BRCA mutation and all of those are at high risk of breast cancer if nothing else. It's a smaller proportion of unselected breast cancer though in certain subgroups such as triple negative it's over 10%. I would certainly like to see and what I hope the new technology will allow us to do is to offer BRCA testing to all women with breast and ovarian cancer. So what are the challenges to the implementation of that? Well, we need cheap quick testing and this should be achievable. Obviously there's also the issue of patterns which I'm not going to talk about today, partly because I'm not able to talk about it unless I've junked quite a lot of gin. So I'm assuming that that bit will be solvable. We need to have quick, simple report of the results and that will have to be readily understandable by non-genetic experts and we will need that to be then triaged into what the clinical actions should be. So where are we with that? We're a long way off from that. So we saw this slide yesterday from Les. This is one of the ways in which classification systems for BRCA variants are used. We don't use this. Why don't we use it? I think there are a number of different problems. It is a fairly arbitrary system based on various assumptions. That sounds like criticism. I don't mean is it criticism. I think that taking your best guess is the bedrock of clinical practice and science. I don't have any problem with that. I'm not sure that if you are guessing that you should quantify that to three decimal places. And I think that if you are having an arbitrary pragmatic system you should try and have it as simple as possible and it should be tailored to the aims you're trying to achieve. I think this is very laborious and many variants you just don't have the data in order to classify it. But I think the main problem is there are five variant classes but there are effectively only two management things. You either can manage it as a positive or a negative. And therefore, if you're trying to have this system you have to be able to tailor that into your management strategy. So I get daily emails, I think, from people around the world where they've got variants that are in classes two, three and four and they don't know what to do about them. And again, going back to these things that most people sort of think of things as being guilty until proven innocent, there have been hundreds of women who have had their breasts removed on the basis of variants that are highly, highly likely to not be increasing their risk of breast cancer. So in part to manage my inbox and in part because we wanted to think about trying to make this more user-friendly. Over the last year we've been using a different system and this is a system that we use. So we have a variant category but it's very much tailored towards going to a management category and in the management category it's either negative or it's positive. And I think the key difference, which was a slight moment of epiphany in my group, I think, was that instead of trying to classify every variant individually, there is a default category that when you first have a variant if you can't do anything else to it, it goes into what we call our variant two category. So if there's a mis-sense variant that's never been seen before, you actually can't move it into pathogenic, you can't move it into four and that just goes straight, that's into and it goes straight out to getting our report. If a variant has been seen before and has been previously categorised, obviously it goes into that category. If a variant is a frame-shifting mutation, you can just code that, that will go straight into pathogenic because we know that it doesn't matter whether you've seen it before or not, if it's causing premature protein truncation, it is pathogenic. And then we have, the possibly assignable is for the group where there is some information in the literature but or available but it's not sufficient to say it's pathogenic and here we're using genetic information because at least for the BRCA genes there is no robust in-silico predictive information or functional information unless it's showing that it's the equivalent to a frame-shifting mutation that will allow you to call that pathogenic. So those are the categories that we use. This is, following Howard's example, this is one that I did this morning because I had one in my inbox. So this is a variant here which has not been reported before. In fact, the in-silico predictions and conservation wouldn't suggest that it was pathogenic and so that goes straight out to our variant too and this is what those reports say. Managers are negative BRCA tests. The consultee should be informed that the BRCA test was negative. I think the next bit would be a point of discussion, possibly a point for transatlantic difference. A discussion of the variant is not required. There's a management recommendation. Breast surveillance should be recommended appropriate to family history and we have, that goes to a protocol. We have a number of protocols on there. The only rule of thumb is that no protocol can be more than one page. No predictive testing should be offered for this variant. No additional analyses are currently required. So is this model transferable or scalable? I think it probably is both. At the moment our reports are going back to geneticists or genetic councillors because those are the people who are doing those tests but I can see how it could go into oncology. If the oncology people were doing the tests, the negatives would just be negatives. In terms of the positives, the report would be slightly different. You'd have the information that the oncologist potentially would be using and then there would be another thing that would say refer to genetics. So here, instead of genetics having to see everybody, we're seeing the positive people. We will do the genetic information. We will be doing the cascading and we can manage that in terms of ours. What we can't manage is seeing everybody who's going to be negative. I think there probably are other genes and systems for which it is also transferable. We often would ask what you need, what I would really like. I said yesterday, I think we need more data. I think we need population data. One of the major areas where we're doing mismanagement is when you've seen a variant that's been seen in cases from a particular ethnic group. It's assumed to be pathogenic because it's been seen several times from a particular ethnic group but the equally plausible and I would say more plausible thing is that that is a population-specific polymorphism. Unless we have really good data on these low-hanging fruit key genes from lots of populations, we are going to keep making that mistake and I'm not clear that we're just going to get that data unless we directly try and get it. I think it also does give you better information about the spectrum of mutations across there and because BRCA1 and 2 are old genes, there's virtually no sequence data from control individuals and BRCA1 and 2 because it was sort of done before. It's still quite a herculean enterprise but it certainly was then. We clearly need much, much better predictive in silico methods that's a given. What I'd really like to see is some standards for deciding, for us as a group or some group, to decide if genes or variants are definitely pathogenic. So really thinking about which ones were classifying into that group. I appreciate that all the others we need to sort out as well but at least if we can sort that out. I want to just finish on a sort of caution retail to exemplify that. So RAV51C was a gene that was published in nature genetics, very high profile about 18 months ago and it was published as a high-penisurance breast ovarian gene comparable to BRCA1 and 2. It's got anomim entry, BRCA3. I'm aware of at least one woman who's had prophylactic mastectomies because they have a mutation. It was a little unusual, this paper, because in it truncating mutations are only found in breast cancer cases if they were in families with both breast and ovarian cancer. If you looked at families with just breast cancer only, there were no mutations and that's obviously odd for a high-penisurance breast cancer gene. Subsequent data, nobody was finding any truncating mutations but they were finding mis-sense mutations. They thought, alright, the mis-sense mutations are causing breast cancer. That wasn't the original hypothesis and no controls were studied. For a variety of things I haven't got time to go and we were working on another gene which is an ovarian cancer gene. Anyway, we've looked at this and this is hopefully shortly going to be published but it is also consistent with all of the available data including the original paper, I should say. So we did a large case of control resequence suddenly looking at both cases and controls. RAV51C is an ovarian cancer gene. It has a decent size risk of ovarian cancer, about 9% lifetime risk, but it doesn't predispose to breast cancer. So what's going on? I think it's fairly old-fashioned ascertainment bias. If you've got a gene that causes phenotype A, in this case ovarian cancer, and you look at phenotype B, which is breast cancer in this case, but the only breast cancer cases you're looking at are relatives of your phenotype A. You are bound to see an association unless you correct for that. But if you look at phenotype B on its own, which they did, you're not going to see an association.  But you can see a potential where if we'd had the whole genome data in the electronic patient records, and that data was already available and the gene comes out, you're thinking, right, it's high risk breast cancer, you can see there's a situation where a lot of women might have thought, right, I'm going to have prophylactic surgery or act on that. And I think we're in an era where there's going to be lots and lots of new gene discoveries. When you're writing a paper, it is perhaps natural that one's optimistic about the clinical utility of that. And there's often in that paper, but I think there needs to be standards or principles by which people can look to see whether it has passed a bar where it is ready to be used in the clinic. And I think we need to think about that now, and I'll finish then. All right, I think we used up our question time. Sorry, unless somebody has. Heidi, do you have a quick one? Just a quick question. You mentioned recommending no management in cases where there's a not assignable BRCA1 variant. You know, we study cardiomyopathy, which is a very similar paradigm in terms of dominant inheritance and high risk for sudden cardiac death and a need to manage those family members. And we would always recommend familial testing to look at segregation in order to determine the clinical significance of those VUSs. And once you get a high enough LOD score, you can say with statistical confidence that that variant is pathogenic and then use it in a predictive fashion. So I'm a little bit concerned about not encouraging those physicians to pursue familial studies, which can be extremely informative in terms of pathogenicity. So I think that with respect to those class three ones, we certainly do do that. All the class three ones, we then would recruit into our research and we would do that more broadly. I think this does speak to things, what should you do with just any VUS? And it then also speaks to the fact that are they innocent until proven guilty or guilty until proven innocent? Now, the one I talked to you about, in fact, all the in-silico things would say that it's benign anyway, and we know that they're mostly benign. We're not doing that for synonymous variants. So I think in terms of going, often you can't do the segregation, the families are too small, the chance of being able to really sort that out in terms of a lodg score for breast cancer, which has got a high phenocopyrate, which also impacts in that, so it makes it very difficult. It's quite difficult. So I think the problem that has is people go back to them and you're telling them, if people knew that it was innocent rather than proven guilty and they were doing it on a purely exploratory fashion, I wouldn't have so much problem with it. But I think what happens is people are assuming that if the doctor is telling you this or the doctor is actually telling that it is likely to be pathogenic, that we have a problem there, and so currently we're doing more harm than good. So it's part of that balance, but I appreciate it's a difficult issue. Great, thank you, and we'll definitely have time after the panel's all done for more questions.


What's going on everybody welcome back to some breaking news and we have more seeds losing at the Miami open some big names some Grand Slam Champions are out of the Miami open. Let's go straight to the list starting on the men's side We have number three seed Alexander's verov He lost in the second round number eight seed got fine also lost number nine seed Dmitrov number ten seed for Nini Ojalia seem the 11th seed he lost as well 13th seed Garin He's out 14 seed Hashinov is out and also the 15th seed Alex Diminor He lost in the second round as well going over to the women's side now and some big names are out Simone Halop she withdrew from her third round match number three seed of course the number four seed Kenan She also lost plush cover the number six seed She is also out Kiki Burton's the tenth seed is out the 11th seed Benchich 13th seed an Australian open finalist Jen Brady she's out 15 seed French open champion of last year is also out Sveontech and the 17 seed Conta Also out of the tournament so big names are falling at the Miami open and we're only about halfway through the tournament There's still another week to go quarter finals semi-finals finals are still up for grabs some massive names They're gonna be missing. Let me know down the comments below. What's the biggest upset so far this tournament for you For me It's got to be Zverev and Kenan because Zverev was coming off the Acapulco title and Kenan She was the best player of last year and just hasn't really gotten into that form this year Let me know down in the comments below. What's your biggest upset the Miami open? We're about halfway through and big names are starting to fall


The Egyptian legend says that if one wants to enter heaven, at the point of entry you ask two questions. Only if you are one big yes to these two questions, there is entry for you. The first question is, have you found joy in your life? The second question is, have you given joy to those around you? I must tell you that if you are one big yes to these two questions, you are already in heaven. May you know the fulfillment of making all that you touch joyful. May this new year bring much bliss to you and your dad once. My blessings are with you.


This study investigates the effect of binding events on the work function of gold surfaces. It was found that binding events can cause a significant decrease in the work function of gold surfaces, which can be detected using Kelvin probe force microscopy. Additionally, it was observed that binding events do not affect the work function of gold surfaces when they are exposed to non-binding antibody solutions. This article was authored by Cynthia D. Franco, Eleonora Machia, Lucia Sarsina, and others.


So guys today I bring you a gameplay trailer of Tiny Tina's Wonderlands and I will warn you it looks incredible those hyper levels are going to be through the roof trust me people and if you haven't seen this yet check it out right here then I'll give you my thoughts on it after. How great did that look guys I mean I'm loving more or less every single aspect to this trailer the amazing looking new characters cannot wait to learn about them I like their hints a big head mold from Borderlands I like the basically just looks like Borderlands but just better dare I say it I mean yes it's early days to assume that but Borderlands 3 to me was a big hit I really enjoyed the game I mean it wasn't quite Borderlands 2 but it was still a great great game but this to me just looks like it's going to be one better now in terms of the gameplay it does look a lot like Borderlands as you would imagine but some of the abilities we see here look absolutely incredible and I cannot wait to learn more about them and the players that use these abilities we also see snippets at new areas too whether these are different worlds whether these are just different parts to the same world but what really stands out to me and I can't wait to explore is the kind of party treasure island the themed area where we see all these amazing looking enemies the skeletons the sharks with legs that are not yet the big sharks that run on all fours I mean it just looks absolutely amazing we cannot wait to learn more about it and as per usual guys there will be that loot for us to farm for now I've said this in the past and I'll say it again when it comes to these loot shooters in my opinion 2k gearbox they know exactly what they're doing and they get it right in my opinion almost all the time so yes all those details right now on the game are a little scarce I mean we know a little bit some bubs but in terms of the characters new characters we will learn and play with what we can do what we can build what we can experiment with I mean the details are scarce I mean going off the trailer we can see there's quite a few abilities being thrown about here there's quite a few new kinds of weapons like swords I'm seeing I'm seeing amazing looking bowls we're seeing quite a few melee weapons I'm seeing tons of loot in fact I actually see a couple of weapons straight from Borderlands 3 I believe but yeah Tiny Teeners Wonderlands this was PS5 gameplay like I said this is released on March 25th 2022 it seems as though they're going to be through editions standard next level and the chaotic great edition and as soon as we do have more details on the game obviously I will have you covered right here on my channel now I built up a little community when it comes to Borderlands through BL3 and I will be sure to be posting plenty about this and playing and covering it on my channel when it does release now like I said as soon as more info comes I will have you covered right here on my channel so if you're new around here make sure you subscribe but yeah people I cannot wait tell me your thoughts down below what you think about the trailer what you think about the gameplay how does it look to you do you think it looks fun as I do do you think it looks like that typical Borderlands game we should we all know just won't let us down what do you think let me know down below but guys thanks as always for stopping by and hopefully I will see you on that next one


T F N N headline news update Welcome folks. We have the Dow Industrial's finished down 191 Nasdaq was down 96 S&Ps off 26 and if we do take a look at the ETF structures folks they come down with some volume so coming into a powell tomorrow at the speech it looks like lower prices are coming at us let's go take a look at the embassy volume and see if that matched because earlier it didn't match it no it's still not there so yeah we have some divergence there that's big divergence so yeah so you know when you get divergence like that it's not telling you anything that's the real bottom line now I stick what ends up happening when I take a look when something like this happens meaning that whether you go up or down in this particular case we came down and what do you pay attention to ETF structure or the industry structure I pay attention to the ETF structure and the reason being is that so many of us are trading ETFs that's what it comes down to so inside the ETF structure it's like hey listen you're down 238 on the cues you're at 372 42 and that's telling me we can go to the bottom of this range out here which is the 368 that's from Monday and if you do get some fall through and volume then that lower end is going to be gaming a 355 to 353 gold gold contract out here you can expect that volatility out here tomorrow on gold to folks gold's in an ABC structure in the way up and I expect we're going to get that ABC structure we're up 350 you're trading 1794 gold one the ABC structure is 1980 1994 yeah 1994 and the high is 1922 no 18 I'm sorry 1894 1894 and the high is 1922 so I expect we're going to get up there and if it's if that's the fact then this dollar tomorrow I suspect was going to have a tough time we'll see if that's the case but the bottom line the dollar caught a bit out here today it's up 230 trying to get into the downdraft from Monday the downdraft from Monday got it from 93 500 to 92 900 and we're right at 93 56 right now so we'll see whether they basically can get into that area my take is that we're not going to get into that area and then notes and bonds there they're there they're there the trip man there's no doubt now we haven't hit the lower end the lowest swing point but man the volume that we are coming into it is monster so my take is that we will hit this lowest swing tomorrow have a great night folks have a safe night thanks for joining us please tell your friends about TFNN ask them to go to YouTube search TFNN subscribe it's free come join us tomorrow morning Tommy kicks us off 9 o'clock you want the action with good forward speech 9 o'clock in the morning have a great one have a safe one folks


What's going on everyone Sam here with late in sports cards ripping Sunday fun day NFL 50 box 2017 National Prism Treasures football mega mixer random team style Let me grab you your Results as always you can find those on the website under the results tab As well as the Lincoln chat all of this and then down good luck Jerry Judy I would say probably you can always hit L way stuff to like the vets and stuff They have here. I'm gonna zoom the camera out the top cam. Just you can see all the boxes just a bit like that Why okay and okay. All right, we're gonna start with three boxes 2023 legacy hobby Top illegal. Oh, no, we're gonna start with now. Let's start with legacy the draft after yeah You'll have Payton's and stuff to Gevante. Yeah, there's a decent amount of guys and stuff It's an orange Daniel Jones to $1.99 Erlacher Your Gibbs and base that is a Brian branch mini Debo to 125 base orange cam Smith to 199 Charles Woodson Miles Murphy price prospects. Yeah, definitely once we get to like the higher-end stuff There's gonna be potentials for manning 15 NT stuff like that Miles Murphy is gonna be your first on the break going to the bangles. Nice one there sincey. That's Austin Echler I had Rishi rice to 299 Jalen Hyatt rise prospects Tillman was the one I was thinking of that browns Andre Carter refractor or not silver tops Top shake together good together be boo be boo boo. There's a Dalvin Coke to 75 Pink ice of some sort that is Kenneth Walker to 100 Trevor Lawrence pink ice one of 10 Nice one there for the Jags. Congrats Jacksonville Jose you said to use the name a Burberry M I Believe so you have the Patriots. I just I didn't want to put your last name That was the only thing I didn't know if you wanted that or not, but Burberry M is who you are Jose Madison Redemption is Jameer Gibbs under light silver autographs go into the lion's nice one there Go into the lion's Jameer Gibbs box one is down legacy box to What good is a bot that's broken. That's very true Not good Not be good would not be good at all That's Jackson Smith and jig but a 249 going to Seattle. Congrats on that Seahawks as JSN Jackson Smith and jig but Dare Terry be cool Yeah, for the ages Eli Manning Orange to 249 Miles Murphy prize prospects base champ Bailey Decade of dominance and base that is Nolan Smith a Derek R. Mini Saints Jalen Hyatt Prize prospects Shocked if it's not but Gino to 299 Generation Echler and LTE LT again thick one coming up here sticky That is three of 25 Trey Tucker on the NFL Shield going to the Raiders RPA. Congrats Raiders Three of 25 Congrats, Las Vegas Joey Porter Jr. Under the lights blue Peyton Manning for the Broncos the 25 there go Eric I just won there cam Smith orange mini terrace Marshall to 125 base Rikim Jaret to 299 blue underlights Joe Burrow to 35 the Bengals and base last box of legacy then we're into some leaf metal jumbo here and leave Trinity The next couple of boxes will do here Tyree kill Drake London second-year auto for the Falcons 13 of 15 cool one there on the yellow. That's Falcons Rishi rice mean Joe Green to 100 Archie Manning I know second-year Drake London sounds weird. It's like Kenny pick it to like second-year saw second-year pick it Do you want to battle silver second-year ridder? I know my god second-year Brock Purdy Brock Purdy sounds like he'd be a rookie for the rest of his life second-year Romeo Don as Jordan battle to 75 bronze mini second-year Rashad wait Yeah, I agree on that Vaughn. There's CD lamb to 199 Had a orange on the light stack Prescott behind it to 149. I Know like even especially in baseball this year like second-year J rod dude and second-year wonder Like that doesn't that doesn't feel right at all. It's like bro. You are still a rookie Jordan battle Silverado forget where he is bangles bangles. Thank you, Jake That's Stafford orange Buddha Baker to 199 Devon a Shane CJ Stroud that is a Brian Robinson, Jr. to 75 Josh Downs rookie Right, right, right. Yeah. No for sure for sure illegal. That is a Brian Robinson, Jr. to 150 on the yellow Jump Saturday and base. All right. We are done with legacy now.  I believe he's an eagle three of three Tanner McKee is an eagle so money We've got a Zach Harrison. Yeah, but I think you're right. Yes, Falcons This guy thinks still at OSU Yes, this will be a random to all a Mecca at Bucca two of three I would make a separate pile for the leaf with everything else in terms of randoming, too So I'll be the first one random to everybody Jordan battle that is gonna be going to the bangles here comes the boom one of three We've got a so money of a Travian Henderson.  So that'll be the third random we've got one of one Chase Brown is Bangles chase Brown This will be a different random because it's gonna be Hinden Hooker and Jalen Hyatt six of seven So that'll be the Lions and Giants right there. That'll be a separate random. We do at the end Lions and Giants congrats and good luck on that one This guy of course still in college Caleb Williams Three of seven will be the fourth random Nice one there Three of seven and Then we've got will Anderson one of one red white and blue Production plate going to the Texans congrats Houston very nice one there Second leaf metal jumbo now got a chance If he is a chief Sound right where she rice is a chief one of three congrats Casey. I think this guy's a saint, I believe Kendra Miller Just double check that but yes, believe he is a saint. Yes. He is two of four we've got Josh Wiley Josh Wile is a Tennessee Titan to a four Who nice one here one of one printing plate that is gonna be Hinden Hooker going to the Lions on the so money one of one so money Hinden Hooker Redemption Devin Witherspoon, I think he's Seahawk for sure, but second Yeah, Seattle Seahawks. That'll be a redemption Next up we've got a Rakeem Jarrett for the Bucks Rakeem Jarrett bucking ears so money one of five a one-of-one is signed at press proof of Miles Murphy Bangles, yes, this will be another two-way random Between the Cardinals and the Eagles that is one of four Michael Wilson and Tanner McKee So Michael Wilson is an Arizona Cardinal and his teammate in college was Tanner McKee Who is a Philadelphia Eagle? Just make sure that nobody owns both of them Eagles Chris D. Yeah, Chris. I think I'm on spot. We've got printing plate one-of-one is CJ Stroud, wow go into the Texans Congrats on that Houston nice one there CJ Stroud plate and Then going to Lions Jameer Gibbs one-of-one crystal black press proof Alright on to two boxes 22 leaf Trinity points random as well I'm assuming At least because there could be more duals to all right, so I think this will be Yeah, this is gonna go to the Eagles because he's now a coach actually Carson Strong Carson Strong think he's still in college Yes, Cal Poly Sam Heard or Heward 12 of 49 we've got a Tyler Beatty that'll go to the Broncos right there Tyler Beatty. He is currently a Bronco in the USFL Going to the Titans that is a Traylon Birx RPA Traylon Birx for the Titans and then go to the Panthers Brice Young On the redemption good stuff there Good stuff there. All right second box of Trinity now We'll do you could put what's this face here it in with the other leaf cards Yeah, that's fine as the first one as the fifth one. Yeah, so the he word will go into the What's it called into the with the metal draft? Yeah Just as like the The fifth part all the college stuff will just all be randomed at once Max Johnson 15 of 75. I don't know where he is. He might still be in college. Yes, Texas A&M So that'll be the sixth one with the college card random to 75 Going to the Texans that is Damien Pierce to 49 Damien Pierce We've got it. Oh, that's nasty. That's really sick actually that is gonna be Kate Aten going to the Bucks Bucking here is 49 49. This is the best patch. I've seen either so far How about Tyler Goodson with the Iowa Hawkeyes patch five of five? Dude, that's so cool. I think he's a packer. I believe Dude, that's awesome. Look at the patch on that thing. That'll be going to the Packers Congrats Green Bay Tyler Goodson Five of five so cool and Then of course a Joe Montana to 30 going to the Niners. Congrats, San Fran. Isn't that sick, dude? All right, one box 22 Don Russ hobby now Leaf Montana classic leaf Montana best Montana Joe Leaf Tana Free solid rookie that is a Peyton Manning kind of picket and purple Keenan Allen to 106 Just because it's not licensed Adrian That's really the main thing with most people Bo Jackson gave Davis Perry on Winfrey Darian Mathis Vilas Jones Jr. Aaron Donald Antonio Gibson Sauce rookie that is a some of your white the rookies in Hutchinson portrait Probably not Unless they get bought most likely not way mafia That is Jay Jetta's George Pickens portrait and Jonathan Allen to 95 the commanders Yeah, usually Johan Dotson usually it is Juanito Cam Acres on the auto to 99 for the Rams Nice one there Los Angeles Cup Josh Jacobs EZE and base Superlative. Yeah, I leave pearls nice to they do a good job with Pearl Brady Kenneth Walker Miles Gaskin Sick Jersey Which one? Yes, it was awesome Cooper cup to color patch to a hundred for the Rams ramp sweeping the hits in this one box Congrats Rams. That is a T Higgins, Najee and Cooper cup red and now It's kind of unnecessarily thick Missing nameplate Eli Manning The Giants a little short print there and Devonte Smith second here. That is a George Pickens the rookies Drake London and base Jalen waddle Jordan Davis red raider rookie Bosa and Bradley Chubb Honey picket rookie Echler Taylor wrap chase young Mahomes dominators Drake London and Matt Stafford to 100 in Hutchinson Dami Brown That's the Andre Swift and Alvin Cook on Dotson Kurt Warner and Jack Youngblood All right 22 Don Russ elite hobby. Hey picket rookie Elise Stafford spellbound to 99 Christian Watson nice one there to 199 That's on that one Packers bat Judon to 399 See Higgins and base Rookie on deck corral Alvin Camaro razzle dazzle super short prank Congrats Saints That's Juan there Devin Duvernay to 349 full throttle for the Ravens Close my momentum Sam Howell the 999 managers Justin Herbert throwback full thrower playmakers Mahomes elite deck Derek Henry Elite deck Aaron Rodgers There's Jake Plummer Jake the snake throwback threads to 299 for the Broncos. That's awesome TJ Watt elitist. That's pretty cool. No purple pitman to 99 bummer Like Pierce to 999 for Lawrence to 24 nice one there for the Jags. See law. Yeah Broncos heating up. Oh, yeah Damian Pierce pen pals auto on the purple nice one there for the Texans scratch Houston Damian Pierce, there's a Derek Stingley to 99 Texans as well Chris a lot of con Steelers to 999 They can all day it's base Fila our Laftis rookie on deck for the Chiefs Fila again Kyle Phillips Rookie to 399 Lamar Montgomery and base Back here clay makers Camara and base All right, we're gonna do three boxes of Don Russ optic retail 22 now These out. Oh, here we go Blue stars Nico Collins See a downtown out of this. Yes, I believe he is Stefan Diggs. He has a Super Bowl downtown for sure Peyton, I don't think so Eli is Peyton is not I Don't think Peyton is now that I think about it Premier white like any Broncos are in there unless Ross has one Antoine Winfield junior blue stars Blue stars Kevin Byard Kyle Hamilton Rookie Jeremy Rucker blue stars sky more rookie Oh, they do perfect beautiful. Thank you Vaughan That is a Juan brisker I know the downtown checklist is actually pretty big this year. I forgot it already Montreal, Washington a Kyra Elon Kenneth Walker Christian Watson Aaron Rodgers hollow Jalen waddle Drake London Rookie Say Joe Namath retro series Carson Strong a red hot rookie of Garrett Wilson Hollow David a job Davis would be sweet. Yeah, it was to be really sweet box two of optic retail Blue stars luxurious Sneed I need to stare at the chrome checklist for an hour Desmond Ritter great iron kings Marquis Brown sauce rookie Stefan Diggs for the bills Yantai Ingram Rashad white Blue stars a Rob Say blue stars T Higgins George Carl Aftis Picket rated rookie Blue stars Tyree kill Blue stars Tyler Algeri Johan Dotson Retro series JMO JMO Draft Kings Like that one Uh, breeze off Damian Harris solid for the Patriots That's Joe borough my house and those white unis They're clean. Alec Pierce blue stars. I hate to admit it, but they're so cool And Tyrion Davis press. All right last box of Don Russoptic retail now everybody. Good luck. Good luck. Good luck I'm your white Coralton Sutton blue stars Blue stars Jordan Brooks George Pickens rookie Jeremy Rucker Joe Montana blue stars Blue stars Nicobi Dean James Connor blue stars Say Jerome Ford rookie Jalen Tolbert Kyler Helan Trey McBride Say light it up Damian Pierce rookie The rookie is Christian Watson Majai Sanders hollow and Khalil Shakir A Diamond Henge Jamar Chase Hollow Ryan Tannehill Drake London Cross rated rookie A red hot rookies of Desmond Ritter and David Jabba. All right. I'll do it for an optic retail We're gonna do Chronicles draft next One box 23 at Chronicles draft hobby You might have to stick you know some probably will have to stick you know some Base base that is Cordell Flott Cordell Flott He's somewhere I believe Could be right on that He is a giant wrong answer you know Cordell Flott That is a Joe Montana blue to 99 See the Marvin's Minspire Zach Charbonnet, there's a Noah Sewell. I believe he's a Cardinal Noah Sewell Oh bear just kidding. You know who I'm thinking of it's uh Noah Sewell is yes Chicago bear. I'm thinking of Ojalari because he's Aziz's brother and that's uh, what's his face his brother? Penna. Penna. Yeah That is a Tyree Wilson and 99 for the Raiders And CJ Stroud There's nice Quinn Johnson For the Chargers to 75. Congrats Los Angeles Quinton Johnson Josh Allen Lamar Witherspoon and Justin Herbert Jerry Rice Orange Gronk Not number Bryce Young for the Panthers to 149 Hollow Bryce Young as well and Jalen Hyatt Dantebion Wicks Packer going to the Packers Uh full coverage Jersey card Got orange of Tanner McKee Jalen Carter That's a Joe Burrow for the Bengals red to 149 Michael Meyer and Eli Mann Tank Bigsby Drew Sanders To 199 He's somewhere for sure because he was in uh legacy Uh Broncos, there we go Broncos Drew Sanders to 199 Broncos on Drew Sanders Jameer Gibbs Kshon Butte to 75 for the Patriots Rice Young and Zay Flowers Okay on to four boxes Don Russ optic T-Mall Asia 22. All right, do those four Move these four right there red stars here Hollow Deck hollow Trey McBride Red stars Fred Warner and Jeremy Rucker Under Asia exclusives Kenny Pickett hollow rated rookie nice one there Pat Fiermey with and Brock Purdy red stars very nice Rats on that one there Niners Drake London Humphrey hollow Daniel Bellinger That is a red stars Vic and Trey McBride rated rookie Asia exclusives JC Horn Jalen Petrie hollow rated rookie Red stars Mark Ingram and red stars Evan Neil All right, we're going to go to 2022 elements now 2022 elements one box Nice that is a super short print fire of Zach Wilson going to the Jets Rats on that New York And those are not numbered they are just short printed We've got a purple 26 to 54 Malik Willis We go into the Titans That's Titans We've got to 25 of 70 Damien Harris electric Jersey car for the um Patriots followed by to 125 that is Trayvon Walker Rookie neon signs orange for the Jaguars And then our last auto of elements Raheem Moster Steel signatures to 199 going to the 49ers Congrats 49ers All right one box 22 gold standard now Nice Garrett Wilson to 75 For the Jets We've got a Matthew Stafford to 99 for the Rams Jersey card is the Ante Johnson to 299 Let's go into the Steelers Gold gear Got another Jersey card That is a Tray McBride to 399 for the Cardinals Next up is for the Eagles Kennedy Brooks rookie auto to 199 Congrats Philadelphia We've got a nice golden debut of 49 Breece Hall go to the Jets I just won there in New York Congrats Jets And then a Traylon Birx 34 49 Two color three color two color RPA for the Titans Congrats Titans Very cool All right let's get on to 22 Chronicles hobby now Two boxes of that Pretty much going in order at this point Okay 22 Chronicles hobby Two boxes We're starting to make a dent here Jake Starting to Starting to Bob's Romeo Dobbs again Oh Marcus Colston superlatives for uh invincible auto 4 of 10 going to the Saints Such a slept on receiver bro So good Marcus Colston Bailey's Appie Silver Sauce and Terequilin We've done some big like NBA Finals mixers in the past Kway Walker that is going to be a printing plate Emmett Smith for the Cowboys Super Bowl Immortality Nice one there Dallas That is a Damian Pierce Red to 20 8 of 20 Kenneth Walker and Skymore It's just hard because there's not as many NBA products a lot of times too Malik Willis Kenneth Walker Silver Prism Black, Matt Corral and Sauce T-Law, Ritter, Brady, Robinson, Alec Pierce Rashad White to 149 For the Bucks Trayvon Walker and a Kenneth Walker The two Walkers Sam Williams There's a Brock Purdy Luminance We've got a Kway Walker on the Chronicles Jersey Card to 199 Garrett Wilson to 299 Grats on that one there Jets Josh Allen, Prism Black and Isaiah Pacheco Zappie Spreece Hall Sam Howell, Essentials Auto 47 to 99 There you go Commanders Grats on that Washington to 99 A Chris O'Lave to 199 Bailey Zappie and Celia Box, dude I'm gonna do the playbook next just in case you want to get ready Once we're done with this What's up? I said I appreciate the heads up Yeah, I got you But James White, that's a David Ajaubot It's 15 of 25, three colored RPA for the Rabins I just won there, Baltimore, David Ajaubot That's gonna be a gold Chris O'Lave scored a 50 Christian Watson and Sam Howell I did not actually JT I did not see the Gachie K.O. I should go watch that though Dotson, Howell, Christian Watson to 149 George Pickensilver and A.T. Law Pickett Rookie, Photogenic Hertz, Burrow, Zappie, Tariq Woolen to 199 Brian Robinson, Jr. Prism Black, Kenneth Walker Desmond Ritter, Malik Willis There's a Taekwon Thor in On the three colored patch to 25 Timeless Treasures for the Patriots Taekwon Thor in We've got base No, that's a purple of Justin Fields to 49 A Bailey Zappie base chrome And a Pickett Rookie Miss Cut, Pickett Rookie a little bit Goods Juan Dale There's a Kenneth Walker On the Timeless Treasures, Jersey Auto to 99 Congrats Seahawks Nice one there, Seattle Kenny Pickett Silver Rookie Kenneth Walker And Isaiah Pacheco Silver Chris Dyne- Or Chris Dynegon Olave I almost said that Chris Olave Dynegon Damian Pierce and Trey McBride Good Lord, that would have been stupid And guys, seven to go on mega dual case Up next we've got one box 22 playbook hobby Here everybody Got a nice Down and Dirty to 25 Kareem Hunt game used for the Browns No, this is Patrick No, this is Patrick We've got a Brian Robinson Jr. to 199 Mammoth material That is going to be Rookie Auto Louis Seen Let's go into the Vikings And then a Breeze Hall Rookie Pache Auto Booklet 12 to 49 going to the Jets Congrats Jets PTSD there 22 contenders now Start pushing some of these forward here I don't know Not a crispy crab Again, we'll do the round numbers Round numbers will be a dice roll If we get any, I'm assuming we will Is Michael Carter to 99 The Jets space Chris Olodakon is going to be your first auto For the cheap space auto Got your cheats Base Woodson Hershel Walker Gladiators We're going to have two dice rolls here, Jake That's going to be a Quentin Nelson, T.J. Watt One, two, three, left, four, five, six, right So this will be the pairings That is going to be a two Going to go to the left So I just say contenders, duels Yeah, go left And then we'll have the round numbers At some point that will go up or down as well For both Drake London, Rookie of the Year contenders That is Louis Seen Variation Rookie Auto for the Vikings Got a couple of loose scenes now The horizontal variation base I've seen some scenes Safe one Get him out Too late Get him out The Forest Buckner power players James Cook Blake, how you been, man? How's it up there? Neil Haunter New York Long Island Or Staten Island, I should say Staten Island Game day ticket base Yep, there's a round numbers So this will go for both this year and last year One, two, three, top, four, five, six bottom Unless it's auto to one to one It's going to be a five Going to go to the bottom The round numbers will go bottom Oh, we got one of those like metal tickets here That is going to be a David Bell For the Browns Nice one there, two, ninety-nine Congrats, Browns on the on-card Metal ticket Silver ticket, I don't know Whatever you want to call it, honestly I forget what it's called on the checklist But they're pretty cool Nick Mewes That'll be going to these Vikings On the base auto And Jordan Brooks Yeah, very well could be MVP Lamar I'll give you that Ah, you're probably right Base touchdown tandems Oh, you're about You're about John Mechie On-card rookie playoff ticket to ninety-nine For the Texans There you go, Houston Tyler Algier And base All right, illusions, twenty-two illusions Oh, no Oh, yeah Oh, no Oh, yeah Oh, no Oh, yeah Make it sound Put that down, write that down Pick it Ooh, Matt Stafford That is going to be the hollow heroes Case hit Going to the Rams Nice one there, Rams Very cool Jalen Waddle to four ninety-nine And to two ninety-nine Jay Jedis Funkadelic, believe me To our instant impact is Trey McBride Please don't give me a heart attack Aaron Jones If we even pull one now I knew it was going to happen I was hoping we weren't going to see one But six hundred points random to all at the end We'll do a separate points random as well So that's what, four randoms now TJ, what? Three, because you combined them Oh, yeah And then, no, but then there's these two as well Oh, okay, okay Okay, so there's two Okay It's on the same level as being jingled So can I just put all these together then? Uh All the separate ones Yeah, that's fine That's fine I mean, if we get a lot of points I would just move the points to a different area To two ninety-nine, or three ninety-nine Kenny Pickett And Josh Allen, King of Cards Fifteen hundred, I believe, Firehouse Fifteen or sixteen hundred That is a... Ooh, Kenny Pickett Fifteen of twenty Mystique Auto There you go, Steelers! Congrats on that That's very nice It's a big one right there Fifteen of twenty We'll get that into a mag for sure Leak Willis Red is Josh Jacobs to 175 Mystique Drake London That's a nice picket if I'm not mistaken Oh, God Travis E.T. Engine here, four ninety-nine Chris Olave, Illusionist, rookie I'm really about to get trolled, aren't I? Josh Jacobs, Garrett Wilson and Keshon And God, they were the same team Nice one there for the Jets And Jay Jedis Yeah, it's about to get trolled Wow, no Funkadelics Come on Yes, dude That's Zameer White, first impressions Rookie Jersey Auto to two ninety-nine for the Raiders Not happy Ann Alvin Kamara, not happy That's John and Taylor to two ninety-nine And Illusionist Jay Jedis to three ninety-nine Unbelievable I am I'm severely disappointed Very disappointed All right, two boxes, twenty-two Asia T-Mall Prism I know It's not cool, it's kind of messed up He asked me Nini really got trolled He did I got jingled by Panini That is Johnny Woods, Priest Hall rookie Your choice exclusive is Eli Manning To forty-four, nice one there, Giants Silver, Jalen Naylor rookie Troy Anderson, Isaiah Pacheco, Chase Young Nice one there, Commanders to forty-four On the choice exclusive and a Silver, Trey McBride All right, we're going to do four boxes of select T-Mall now I'm going to move those up We'll move the last stack into view now here There we go Perfect That is all the remaining boxes all in one row now We have made a serious dent, Jake Let's go, let's go, let's go, let's go T-Mall Isaiah Spillert 89 Crystal Lave 89 And Tyler Lockett 89 Johnny Woods Silver Dyed Cup B-Waggs, Bobby Wagner It's nice because we have some that are like base heavy And then we have some like this that takes like a minute to rip four So it's nice, I like the Variation The variation of it, yeah Mack Jones to 89 That's Brian Burns to 89 Kyler Murray to 89 On your dragon scales Jalen Hertz and Sam Williams Rookie Dyed Cup Silver Base We're more than halfway there One, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, fifteen, sixteen, seventeen, eighteen, nineteen, twenty Yeah, more than halfway there now Yeah What? Yeah, Trey McBride Justin Herbert to 89 Nick Bolton to 89 George Carl Aptis and Tresson Ebner Well, we did a lot of like, like the the optic choice that was four right there Then there was another four right there with the select The 10 cases of Bowman Yeah, true I've done that, I did that twice actually to be fair No, I did that three times No, I did a 10 case or twice and I did a 20 case or once And then I did a 10 case or of Bowman Chrome hobby and choice Cam Jordan to 89 Mike White to 89 Tyler Conklin to 89 Peter Dolphin Derek Stingley and Trevor Lawrence God Two boxes select H2 now He's gonna leave him the glory Who Mike White Well someone inevitably gets injured He comes in to back it up Silver Devin Lloyd Red Disco to 49 Ecom McWannu Traylon Burks and Samir White Leak Willis Rookie Erica Zucama Silver Dawson Knox Red Disco Trey Lance 2.49 Josh Allen and Aiden Hutchinson Rookie Christian Watson Rookie McBride Iguanu Derek Carr Disco Jared Goff And Boye Mafe We got an RPA in here So we do Strange Strange Harris Bailey Zappie Four of 25 On the RPA For the Patriots Here we go Jose Slash Burvery Blue is Amon Ross St. Brown to 25 Juju and Daniel Jones Box O select H2 Fred Deshaun Watson To 49 Kyler Murray And Drake London Rookie Silver Cam Taylor Britt Blue Zidarius Smith To 25 Isaiah Lightly And Pierre Strong Jr. Silver Kyle Hamilton Rookie Red Disco Damian Pierce To 49 Kate York And Snoop Connor Gold coming up here is Jonathan Taylor Six of 10 for the Colts Congrats Indianapolis Deontay Johnson And Kenyan Green Let me stand up for a second I'm going to move the TikTok phone Because it's rubbing up against my forearm And I'm going to be very upset if it continues to do so So yeah, former Colt is right One box 22 select hobby I hope not, Eddie I really truly hope not I'll say Adam Silver Najee Field level And Terry McLauren Field level Gary Terry Ah! Light blue Jay Jedis To 99 The Vikings A filler Jared Goff And Damon Clark Jaylen Hurts White To 35 Nice one there On the sweet level Sweet level Silver Boy Maffa And Mike Will Like that one, Jay That is a Tri-color Kalil Mac to 75 For the Chargers Silver Lamar And Jaylen Warren Lamar Chase Lamar Silver Sweet level And Jonathan Taylor Yeah, I agree, Vaughan Oh, got to try Got to try Got to try here Chris Olave To 49 Rookie Swatches Bronze for the Saints Jersey Guard Silver Kobe Bryant For sure Bernard Raymond Chris Olave Trayvon Walker Silver And Travis Kelsey Field level Red Traylon Birx To 99 For the Titans That is a Chris Olave Face Silver Juju And Nick Chubb Silver Najee Silver Luke Luke G on the Box, I can never get his name right Get a key anything Get a key Get a key Monta Taylor Damien Pierce Ooh, the 199 Desmond Ritter Rookie Silverado Going to the Falcons Congrats Atlanta There you go ATL Very nice Falcons And Bailey Zappi Rookie You don't have to recappy that, Jesse Over Beep-boop Silver Alec Pierce And Alvin Kamara Beep-boop Last pack, good luck Shry-Color Baker Mayfield 2 at 249 TJ Watt Silverjquan Brisker And JC Horne Best box to select there Well, I guess the Ritter is okay 22 Spectra We'll do now 22 Spectra That's down here I believe Yes it is 22 Spectra We go Here we go Kevin Harris No, we'll do the back is Mark Andrews 230 On the green scope Got a Kevin Harris Silver Not numbered but rookie That is going to be 42 of 60 DJ Moore Max Impact On the Jersey Card for the Panthers Max Impact DJ Moore And 299 Fadarian Mathis Rookie Auto Congrats on that, commanders That is a Astral To 40, Vylus Jones Jr. Rookie for the Bears That's a Lydanian Tomlinson Two of eight, John Mechie Dual patches Nice one there for the Texans Congrats Houston Nice one here for the Cardinals to a four Wow, Trey McBride With the Logo Patch RPA going to the Cardinals Floyd, congrats buddy That's kind of nasty actually Got Nick Chubb Celestials Who was 99 for the Browns Next up will be a rookie Spectris 250, Isaiah Spiller We've got a 35 of 60 Deck Prescott on the Catalyst These are so fire This next set is my favorite in all of Spectra That is going to be 30 of 75 Sky High Signatures Amon Ross St. Brown for the Lions Congrats on that one Detroit Last pack of Spectra That is going to be a Deshaun Jackson 10 of 10 Congrats Eagles T. Higgins base Got 53 of 75 Uh-oh is a Monumental memorabilia Garrett Wilson Uh-oh Jake Uh-oh Jake Uh-oh Uh-oh Oh no Uh-oh One of one K-9 Kenneth Walker Gold Vinyl RPA Going to the Seahawks Congrats Seattle That's so nasty You got one of one On the K-9 Laundry tag Get that into a mag for your Seattle Go baby Hell yeah All right 21 Chronicles Draft hobby next I think that's 21 Chronicles Draft Whoa whoa whoa Almost lost the Panini ones Uh let's see 21 Chronicles Draft Next hobby Yep there it is Dude Spectra's so fire It's so good When it hits it hits so well too It's kind of unfair how good it is Javante Kyle Trask Shuba Hubbard There's a Sam Ellinger Jersey card Going to the Colts Nice one there Colts Mack Jones Carlos Basham Boogie Basham Kyle Pitts And red Kylan Hill to 149 Waddle Trace Sermon Christian Barmore Is going to be your auto That'll be going to the Patriots Christian Barmore Congrats Patriots Jaylen Hawkins Ron Delmore Zach Wilson And Dylan Moses Jamie Newman There's Niko Collins Going to the Texans on the Jersey Carp Congrats Texans Jamie Newman Jaylen Waddle Cadarius Tony And a Silver Micah Parsons Waddle Ace That is a... Oh boy Brendan Knox Brendan Knox See where he is If anywhere Not Brandon Knight He is a Kansas City Chief I think that's where he was most recently Yes Kansas City Chiefs According to ESPN Justin Fields Mack Jones Seth Williams Travis Etienne I've heard that's a century Marshall Hell yeah dude This will go to the Browns 13 of 99 Kellen Mond That's where he currently is You got college cards Go to the current team of the player So Kellen Mond will go to the Browns Etienne Mack Jones Red to 149 Field Double Rondale And Elijah Moore He'll book Kellen Mond to 149 Justin Fields Rookie Recon A Tutu Atwell Kellen Mond And Devante Smith 21 Limited T. Higgins Calvin Ridley That is a Rondale Moore Rookie Jersey Otto to 149 Going to the Cardinals Cardinals actually doing fairly well here Congrats on that Derek Henry And Terry McLaurin Scary Terry Ah Tyler Lockett to 75 That is a Kenneth Gainwell Kenny G on the Jersey card to 75 Cut this guy out of here Roquan Racy McMath to 199 for the Titans Rookie Otto Jay Jettas And Christian McCaffery Okay 21 Tendies Tendies 21 Tendies Tendies Here we go It's too late now But yeah no It's good All right so this will go The contenders' duels will be Like the round numbers will be the same on this one Darnell Mooney Nice To 25 for the Bears That's solid Like Bottle's face I think he's gonna be one or DJ Moore Probably DJ Moore I'd imagine Julio to 99 As a Titan Plex scooper I don't think Clayton Rookie to your contenders Jaylin Waddle Yeah that's probably a dumb question I mean Mooney's good Mooney like automatically becomes the top five wide receiver two in the NFL I'd say With the addition of DJ Moore Farve Josh Allen Wow Two of ten MVP contenders Josh Allen On the auto Nice Holy hell dude Let's go Two of ten Josh Allen That's crazy To banger That is so hard to pull That is a big time banger That works Gladiators Bill Romanowski That's like two insert autos in this See if we get like a huge on-card now too Fields I know the craziest thing is it's live That's a good point Rich Sean and Cooper They saw it off for the Broncos That's Cornell Powell on the uh What's it called Ticket stub to 14 on-card Nice one there for the Chiefs If you're gonna get a Cornell Powell Might as well be an on-card Number to 14 That'll go to What time is the round number show So I'll go to Ramon Dre And the Patriots Be a nice possession receiver That's a good point enough Uh, Mack Jones Justin Fields So I'll go to the Patriots again Mack Darren Hall Bass Otto for the Falcons Cluel Mack Tom Brady Supernatural How's Ben? Hard at work over there today Oh yeah I've seen him like once And grind out your guys as personals It's awesome And Eli Manning All right Do our PDEMI ones now Now we'll do 21 Mosaic Choice first 21 Mosaic Choice We got Peacock That is a Christian Barmore Exclusive Rookie And Dax Milne to 80 Silver Najee Nice one there Stefan Diggs Mosaic That is gonna be a Diami Brown Rookie Auto going to Hello The uh Commanders That is a Nebula OBJ One of one OBJ I'm him Nice one there Congrats on that Browns That's nasty Holy cow Dude, I'm jealous of that now As he's a Raven Uno de Uno OBJ Jarvis Landry The Jungle OBJ I'm him T. T. Troll Davis To 80 And A Antonio Gibson Peacock Let's go right there Congrats All right Four boxes 22 PDEMI one now Lot for Jake to top load here Lot to top load Lot to top load It's like equal to Breakers Relate Jalen Tolbert Eight of 49 RPA For the Cowboys Nice one there Dallas Jalen Tolbert I'm not sleepy Can't talk too much Oh Peyton here would be Nasty Eric Holy That is gonna be A Kenneth Walker To 199 Three colored RPA Congrats Seahawks To go with your one of one now Dude that would be J So sick That's so sick Holy To 49 George Pickens That happens There is something inside of that Like card We'll send an empty box and wrapper I don't I That that's insane Nice one there Steelers But you'll get an empty box and wrapper Sorry about that I I don't I don't know I don't know Onto the last box That is gonna be a Bailey Zappy Two colored RPA Two of 99 Four of the Patriots Congrats New England Bailey Zappy Zappy Hour 2020 Chronicles Hobby I think this is the last one we have in the shop right here Where are you? 2020 NFL Trading Cards Chronicles Hobby Let's do it Herbert Burrow Hertz Tua Love any of them Jerry Judy Brandon Iock Cole Comet to 99 He just got a nice extension Red Prism Black Auto Congrats Bears James Morgan Gabe Davis Brandon Iock to 99 Clear vision Herbert Legacy Rookie And J.K. Dobbins Now it's the 49 But it's a one of one since I had something in it Joe Burrow Jonathan Taylor Rookie That's a James Robinson DeAndre Swift Luminance Jay Jeddas to 199 Rookie A CD-Lamb Dynagon And Jonathan Taylor Clear Vision They're going to have a lot in this one I apologize Unbelievable Uh oh Derek Carr Player Warrant Jersey to 299 for the Raiders A Malik Harrison I don't know how he got in for the Ravens Legerius Snead Lamar Jackson to 199 J.K. Dobbins and the Michael P. Wren Because I mean as a Ravens fan Malik Harrison might not make the roster Yeah but at the time was he height Hopkins Ooh ooh ooh ooh to 99 To a tag of Iloa Rookie Red Prism Black Auto Scotch J. and the Dolphins Congrats buddy There he is Yes sir To him on Hell yeah dude Yes There was something cooking in there There was something cooking in there Jaylin Rager Hold on let him cook Uh Jay Jetta's Rookie There's a burrow Dynagon Rookie And James Robinson Tiki Barber There's C.E.H Clyde Edwards He-Lair That's a Darnell Mooney Rookie Speaking of James Robinson Michael Pittman Jr. to 199 LaVisca Chinolt Prism Black Rookie And Michael Pittman Rookie George Kittle Jordan Love Silver Score There we go Another Pittman Patrick Queen Toa Great Iron Kings Jerry Judy Rookie And Antonio Gandy Golden I think next we're gonna do We're gonna get into some of our higher end stuff now everybody Um we're gonna start with 20-22 NT Collegiate First off the line 22 National Treasures First off the line Good luck here we go Yeah this will go to whatever team The player is currently on Or longest tenure if retired Poisson No no Poisson in this break Unfortunately Anthony Including college guys Like Young and Stroud Will both go to the respective teams There is one booklet in this too By the way Jake I'm gonna have to tell you that Jonathan Taylor to 99 For the Colts Sorry Forgot that happens in this sometimes That's empty by the way Isaiah Spiller That is 5 of 25 Going to the Chargers Most of these you don't have to Tag off or anything because it's all new Unless it's like a weird one To 99 Trent McDuffie I.E. I would probably tag this next As I say that That's going to the Chiefs This next one will be going to the Colts It's gonna be Treasured Moments of Gardner Minshew To 99 Gardner Minshew Colts Colts on that one Yes He is now currently an Indianapolis Colts Going to the Patriots Peer Strong Jr To 75 And now I'm actually getting traded mid-break Breaking news Literally That's going to be Zameer White Team Slogans Go Dogs With my dogs at 21 to 25 Going to the Raiders Rats Raiders Booklet is going to be a Trayvon Walker Going to the Jaguars Bulldogs On the booklet Booklet Bookleta Grats on that Jags And then our first up the line Exclusive RPA One of 11 Chris Olave Going to the Saints Nice one there New Orleans Chris Olave Empty empty All right I think it's time for 2015 NT now Good Lord dude 2015 National Treasures There are going to be some names in here dude There are going to be some serious names in this You got the wooden box too You ready for the best sound in the hobby Jake? Oh yeah they're cracking You got everybody ready for the best sound in the hobby Complete silence Here we go God that's awesome 2015 NT There's got to be some absolute weirdos in here Which is going to be awesome I'm so for it dude James Winston true RPA Shot Paramount true RPA I'm going to lose my mind if we pull one of those dude That's so weird to start us off Good Lord We've got a Jimmy Graham to 88 for the Seahawks Jimmy Graham as a Seahawk 11 of 99 That is going to be Jamis Winston Famous Jamis Player warned slash used for the uh That's rookie century But rookie Jamis Winston we're pulling in 2023 Jake Going to the Buccaneers We've got a D'Anthony Thomas That's awesome 56 of 99 Player warned Absolute legend at Oregon For the Chiefs Former Raven legend as well That would be an immaculate grid for uh If you need Chiefs Ravens D'Anthony Thomas will get you some some rarity score This is actually kind of nasty Um that is going to be two 99 Jamis Winston again on the Jumbo patch Oh my god they're trolling me What the tape Oh with Jamis Winston Got another rookie patch this time A T.J. Yeldon 77 to 99 Yeah Jaguars T.J. Yeldon I think this next one's going to be a random as well Max T and Titans is Andre K This next one will be a random We've got dual patch is Uh Marcus Mariota and Bryce Petty Two of 25 Oh yeah T.J. Yeldon Uh I think this next one Yeah this next one is a Raven That is going to be Max Williams Rookie Colossal Signatures Mad Max That'll be going to the Ravens Again that has expired by about seven years now So I apologize on that Raven's still nice This guy was a dog back in the day 60 of 99 That is Jeremy Langford Jeremy Langford for the Bears He had like one crazy season dude Jeremy Langford Rookie Auto We've got 53 of 99 That is a Thai Montgomery Thai Montgomery RPA for the Packers He was actually pretty serviceable for a while Another former Raven legend Thai Montgomery Saint Legend Jet Legend All over the place And then Rookie Auto for the Niners D'Andrew White 26 of 49 D'Andrew White Uh just potentially 2020 NT Lazy Slots That would be it Which I will drop you a link to right now Okay not the best box of 2015 NT To be fair that's not the craziest class in the world Um all right we've got 2019 iMac now 2019 Immaculate Could be some big names in this Let's see it James was supposed to pin it as I'm satisfied I've just pumped on that one Not much we could do here Price Petty almost threw out of your chair Good Lord All right so we have a redemption on the back Mike Alstott That is going to be 2.99 for the bucks This is going to be kind of sweet It's going to the Jaguar Jalen Ramsey That's nasty Holy cow dude That is going to be Game worn Jalen Ramsey This is this card's nuts dude That card's insane Four of four Sony Michelle With the Patriot flying Elvis patch Player worn on the Sony just retired That's so sick dude That's that's an insane patch right there Insane One of the best patches I've ever seen 56 of 99 That is going to be Riley Ridley Player worn for the Bears We've got Ann 34 49 Isaac Bruce That is going to be player worn for the Rams On the iBlack Jersey Auto Grats on that Rams And then redemption Immaculate signatures Patches rookie Drew Lock We'll be going to the Broncos We go into the Broncos Again it is expired See if they have it Get in contact with Penny See what they can do for you All right On to 2020 Spectra 2020 Spectra Tyler Boyd To 99 Yeah this is going to be freaking massive dude 71 to 99 Leonard for net max impact Player worn Jersey For the Jags We've got 39 Of 50 Matt Ryan Brilliance That is Player worn Jersey And for the Bills 30 of 50 Gabriel Davis Four colored RPA On the green Congrats on that one there Bills Tom Brady to 25 Nice one there On the pink Grats bucks That's solid We've got a CD lamb rise above 20 of 40 On the insert 58 of 75 Lamar Jackson High Voltage Jersey For the Ravens And then 28 of 50 Jacob Eason Two colored RPA For the Colts Hollywood second year 235 Nice one there for the Ravens We've got Christian Kirk 16 of 50 That'll be going to the Cardinals 299 Fireworks Al-Shawn Jeffery Player worn for the Eagles That's a name I haven't heard in forever dude Al-Shawn And then 31 of 60 Cam Acres Two colored RPA For the Rams For the Rams All right last pack Come on baby Let's see a QB Say Kyler Murray Hyper to 75 Joe Mixon on the die cut 12 of 50 For the Bengals That is a 47 of 75 Max Impact Josh Jacobs And 149 of 199 for the Jags Caleb on Cheson Grats Jaguars All right we're going to do 2020 iMac next Good Lord dude Holy cow 2020 Immaculate Oh this is going to be so sick 2020 Immaculate Immaculate Immaculate I'll see a Herbie Or a Burrow or a Hertz or a Two of or Love Or a Jay Jazz Or something crazy Lock chain Carson Wentz BC Premium Patch Autographs 2020 He would still be an Eagle I believe Let me double check that Yeah still an Eagle That'll go to the Eagles Carson Wentz We've got a Trey Aikman to 25 Troy Aikman Next up will be a Philip Lindsay 24 of 25 The Standard Game Worn for the Broncos Nice one there Denver Okay a two color patch is James Morgan 6 of 25 for the Jets Next up is going to be 54 of 99 That is a Jared Cook He went to Jared Player worn slash used material for the Saints Marlon Mack Premium Patch Auto to 99 And this is disgusting Going to the Colts Jonathan Taylor 10 of 99 Two colored RPA Congrats Indy Oh that's so cool dude 10 of 99 Colts Jonathan Taylor All right 17 Prism 2017 Prism Good Lord dude So much nostalgia I opened a hobby box of this back in 2017 Did you? I did I got him a Holmes Rooking I graded it actually at PSA 9 I still have it Nice And I graded my Mitch Trabisky out of it as well Back when that was still acceptable What did I get? I got a 10 So great Tom Savage Fell Michael Thomas Whoa Oh my god Jeremy Macklin As a Raven Orange Carlos Hyde That is to 275 Rookie We've got Gary and Conley Silver Matthew Dayes Silver Rookie And Terence Williams Silver As well as a Todd Gurley Silver So all the rookies are silvers in this too Just so you know Cameron Meredith Matt Ryan Chris Hogan Golden Tate Marriota Coleman Theoretic It's going to be a Red Power of James White To 49 That's one there for the Texans The Sean Watson Rookie Got Kevin King Rookie TJ Yelden And Brian Brian Hoyer is a Niner Got what? Oh Forgot about that Good lord dude Joe Flacco Alan Hearns CJ Mosley Todd Gurley Brian Hoyer John Brown Ooh that's kind of nasty Three of 25 That's going to be Corey Davis Rookie Otto on the Camo Congrats on that one Titans Chad Williams Silver Rookie Elijah Hood Silver Rookie Jesse James And John Brown I like the color match Yeah that one's actually kind of nasty I like that I like that a lot Danny Woodhead Is it Raven? Sammy Watkins That's Brian Malachi Dupri It's going to be our second Otto That'll be a Silver Rookie Otto For the Packers Joe Mixon Silver Rookie Leonard Fornette Silver Rookie Silver Mike Evans And Silver Perkins God Giant Legend Paul Perkins Come on see some patty color here I also pulled a gold vinyl out of this My when I I opened it My only My lowest numbered pull to date For myself And it was Charles Clay Jamal Williams Wow dude So weird Jamal Williams as a rookie Introductions Orange Marcus May Is actually pretty solid That is going to be going to the Jets to 275 Silver D'Angelo Yancey Rookie Silver Dante Forman Not bad now Tyrone Matthews The Honey Badger And Brandon Marshall As a Giant We're going to give Jake the Kid Reporter cards Here's a little baby That wants to go to the Super Bowl There's a Brady Bass T.J. Watts Cam Newton Sterling Shepard You know Atkins Robert Woods That's Illumination Of Zeke Elliott Ooh Greenscope Dalvin Cook Rookie 299 There we go Congrats Vikings That's sick 31 to 99 Finally unearthed After all these years Another solid one Silver Miles Garrett Rookie Silver Evan Ingram Rookie Cole Beasley And Deandre Hopkins Yeah soon to be the new Colour Team Colour Match That's Fax Vaughn Carlos Hyde Pete Kelly's Bennett Sam Bradford Orange TY That is 2275 The Colts J.U. Sheson C.J. Bethard Rookie Silver Phillip Rivers Silver And Jared Cook Snacks Harrison Rookie Marvin Jones There's Greg Olsen Purple Ice 275 Nice one here It's going to be a Marshawn Latimore Silver Rookie For the Saints As well as another Corey Davis Silver Rookie For the Titans And Bradford Silver Rookie For the Titans Michael Crabtree And Mohamed Sunoo Patriot Legend Mohamed Sunoo Watching Omar Ashik Highlights Cronk There's a Brady Superbowl MVPs That is an Eric Berry For the Chiefs 2 at 149 On the Silver Wave Man Teese Tabor What a guy that was For the Lions Silver Jared Davis Another Oof man Jordan Howard And Spencer Ware Jadavion Cloney Antonio Gates Deandre Hopkins Jared Cook Mohamed Sunoo That is going to be a Matthew Daze Wave Otto For the Browns Nice one there Congrats Cleveland Brad Kaya He should have lasted longer Boise State No, Hawaii Legend Right He's a Hawaii guy Marlon Mack Rookie Silver Aaron Rodgers And Dante Mancreef Come on See some of the home color That Dalvin was pretty sick, dude Tori Smith as an Eagle Ehh Thomas Rawls We just passed a Thomas Rawls Card Carson Wenz Doug Baldwin Jeremy Hill Silver Dante Forman Rookie Introductions Blue Charles Harris I think I have this exact same card actually To 199 Malachi Dupri Isaiah Ford Rookie Rashard Matthews And Tyree Kill Silver Nice, there you go Dallas All right, last pack of prism Then we're into 2017 NT, everybody Good award After we'll do the random I'll stop the video Then we'll do a recap And then that's going to be Most likely it For the night I'd have to imagine Sir Ware Tyree Kill Darren Lee That's a Rashad Paramon To 25 for the Ravens That's a Tom Savage To 149 For the Texans Silver D.D. Westbrook Rookie And a Cooper Cup Rookie Nice For the Rams Aaron Donald Silver And Latavius Murray All right Come on, baby 2017 NT My first time ever ripping this man Yeah, big hit for the Ravens right there Rashad Paramon Yup Well, yes it was Ready for the best sound in the hobby again, Jake Everybody quiet Bob Gronkowski To 99 Got a base of JJ Watts To 75 It's already in the legacy He's got Jets cards already, Dallas To 25 We've got a Tony Dorsett That is player worn Slash used material Tony Dorsett For the Cowboys To 99 That is gonna be A That's actually sick Richard Sherman Colossal Pro Bowl used material Assuming this will be a random Wow, there's some names in there Wow, there's some real names in there So Broncos Bucks Yeah, this will be a random between these four teams That's actually really cool We've got A One of ten patch Carlos Henderson Chris Godwin Kenny Galladay And Amara Darbow Really really nice one there Player one on all of them That'll be a random between the Broncos Bucks Lions and Seahawks Really cool one there 34 of 49 That is gonna be A Mike Will For the Chargers We've got RPA Three of five That is gonna be A Joe Williams For the Niners This one's actually cool We got a booklet coming up here, Jake, sorry That is gonna be A Dalvin Cook Three of 99 Rookie Patch Auto Booklet Congrats Vikings Dalvin Cook We've got 83 of 99 That is A OJ Howard For the Bucks Alabama tight end Wow And Redemption on the back Is expired, unfortunately Colossal signatures Matt Ryan For the Falcons Matt Ryan All right Wish we had a better box of NT Sorry about that, everybody Still a lot of fun All right, let me see We've got Cheese One, two, three, four, five And six randoms to do We got those done really quick I'll have some wine There you go, Anthony Another one Another one One, two, three, four, five, six So we have what? One, two, three, four, five And then all of the Leaf Guard Six All right, so we'll start off Points That'll be everybody Which one? This one Uh, I guess, yeah Because it's kind of, it's just cool We've got the Petty Mariota That is Titans Titans Jets Jets Um, the Running back quad The Broncos Bucca Mears Lions Seahawks Hooker Hyatt Dual Hooker's what? Lions and then Hyatt's Giants We've got the Wilson McKee Dual Uh, can you double check for me? Michael Wilson to Cardinal, right? It's up MC And then McKee's an Eagle, right? Eagles Eagles And then College Cards I'll be everybody So we'll do that one second Michael Wilson Cardinal Yeah, and then Tan McKee is uh Let me see Believe he's an Eagle Double check that though Just to be sure, yeah Yes? Okay, cool Can I see the college stuff too? The, uh, the Leaf ones Thank you All right, so we'll do the points first I'll send it over We'll do the college one second I'll let you write everything out And then we'll do the rest of them Okay, now start with We only have one points card 600 600 points Um, again, that'll be random to everybody Roll the dice on that We've got eight times One Two, three, four, five, six, seven, and eight That'll be going to the Jaguars Jaguars on the points Um, okay So then we've got the College Cards We have an Ameka Egbuca Trevion Henderson Xavier Worthy Caleb Williams Sam Heward And Max Johnson So the top six teams Uh, after the dice have been rolled Three times We'll win those cards In order of how I just said them Egbuca Henderson Worthy Williams Heward and Johnson So three times on this One Two and three All right, you ready? Ravens are going to get Egbuca The Dolphins We'll get, um, Henderson, right? The Chiefs will get Worthy The Browns, congrats Browns We'll get Caleb Williams The Jets will get Heward And then the Cowboys will get Max Johnson Yes, okay So that'll do it for the College One Now we're onto just the, uh, single randoms We've got the Marriota and Bryce Petty duel Between the Titans and the Jets Rolled the dice on that one That was going to be nine times One Two, three, four, five, six, seven, eight, and nine Going to the Titans I'll have a pen over here I don't think so I'll go Titans We've got the Running Back Quad Of Carlos Henderson with the Broncos Chris Godwin with the Buccaneers Kenny Gallaudet with the Lions And Amara Darbo with the Seahawks Rolled the dice on that That'll go six times One Two, three, four, five, and six We'll go to the Lions Lions on that one We've got the Henden Hooker Jalen Hyatt duel Between the, um, uh, Lions and the Giants That will be three times on that one One, two, and three That'll go to the Lions And then the Michael Wilson and Tanner McKee duel Between the, uh, Cardinals and the Eagles We'll go seven times One, two, three, four, five, six, seven Going to the Cardinals All right guys, going to stop the video here And we're going to do another video for just for the Recap So thanks again everybody I'm going to get this, uh, uploaded


This is an impressive vineyard You like that, Naki? Susanna was like, we have to buy that Like you're in grammar school Limited... Oyster Uncle Riserovo went out The good Super Tuscan Okay We'll have a ceramic Make sure to subscribe to our YouTube channel Click the bell so you know when new videos are out If you like content like this Check out our Patreon page Where you get some behind the scenes exclusive content Thanks for watching Cheers!


You might have seen the picture of Michael Phelps during one of his races where he had all those weird red spots on his back And you're wondering what the hell is that? Does he have a weird skin disease? Is it some strange massage? What is going on here? Well in Chinese medicine, it's actually called cupping or baguang and cupping is one of the it's very ancient method used even in ancient Egypt found in one of the papyrus the scrolls and in this video I want to share what cupping is How it works and what the colors and what the shapes and everything means with the cupping So if you're wondering what cupping is, what does it do? How can it help this video? We're going to introduce you to that Hey, I'm Alex Hein author of the book master the day also a current doctoral student in traditional or classical Chinese medicine Now I've included the first link in the description there That's actually for a free download on five ways or five habits to add ten years to life with traditional or classical Chinese medicine So if you click that link below and you add your email you'll get a series of emails from me and the download there So first of all, what is cupping? I'm going to bust out a little set here So this is not fire cupping. These are just silicone cups that you can use to apply on your own And what I'm going to do is I'm actually going to apply one right on my forearm Let's see maybe the inside so that you can see What it really looks like after it's been hanging out there a while So I'll play two cups While we're here and at the end of the video, we're going to take them off and I can show you exactly what that looks like All right, so we've got these two silicone cups here That are not going to stay. I'll use your small ones And we're going to leave them there for the duration of the video So at the end of the video, I'm going to show you exactly what the shah looks like or what actually comes up and the color changes there So what really is cupping? I mean cupping was found historically even in ancient Egyptian manuscripts I think it one is called the Ebers papyrus probably spelled that and said it wrong But 1500 BC and since then it's been used all over Asia in China and in many Arabic speaking countries as well There's also a variation called wet cupping, which is actually where you bleed the patient sounds more barbaric than it really is You cup over the Area where you've pricked the patient and it will actually draw blood out and one of the ways you can use this is for example You can bleed a patient in varicose veins And even though you wouldn't necessarily want to cup that it's a similar theory where things have gotten stagnant and you can move them again So what is cupping really do like why was Michael Phelps and why do all these athletes do cupping in the first place? One of the things first of all in terms of biomedical lingo and Chinese medicine lingo is that it moves stagnant blood Or it just moves blood and lymph it increases circulation to that area in Chinese medicine we call this moving Qi and blood and Essentially you can see based on what ends up coming up how much quote stagnation there is there Sometimes it comes out very pale colored and sometimes it'll come out very very dark almost black And what's interesting is sometimes there's all kinds of modeling that shows up there can be even a wetness or moisture in the cup overall even though it also We say it moves for example Qi and blood or it moves Circulation and lymph increases lymphatic flow, but at the same time it also stimulates sensory nerves So we tend to use it for example with pain disorders digestive disorders circulatory disorders respiratory disorders Common colds and flus and even atrophy disorders Now generally speaking the darker the shah the more stagnation or blockage we consider So I'll show you guys a little bit of a cupping a little mini cupping silicone set I have here So you've got a couple different sizes of cups You have ones about this big even with the fire cupping as well and then you have So this one I only have three sizes. So this will be the biggest This will be the medium size and Then the small ones are currently on my arm with the shah I'll do one here actually on my calf So I can show you guys So I've got a big one the silicone ones are super simple because basically the only thing we're doing is just applying some suction You can see It's pulling up a little right With fire cupping it's much much stronger because you're creating a vacuum there And so you're getting a lot of suction and a lot of pull These you pull off you can see almost nothing. All right, but I'll show you What this looks like now so All right, you can see this one on the inside of my form It's one of the outside and you can already see the discoloration here, right? And I'll take this one off so you can see There's some discoloration here that would be maybe Maybe light to moderate And obviously my form is kind of an unusual place to cup You wouldn't normally cup that but I wanted to show you guys because I don't have a the person to demo here And I'll show you what my other side looks like This one is much redder You guys can see that one Much darker color and so really this one see this is already gone This is really almost no Shaw, but even that pretty big difference And It can get much much darker than that, but this is kind of you know do it yourself a DIY silicone cupping set Honestly, it's pretty good. This is not too bad to do some self cupping But it's not gonna be as strong as the fire cupping itself Now I hope that helps provide some insight on what cupping actually is and what we use it for So Phelps and other athletes are probably using it because they have sore muscles and probably even tendon injuries So they're probably it's an attempt to increase blood flow to that area So that's a very simplistic way of using it again if you want to stay in touch You can grab that free download the first link in the description Five habits to add ten years to her life with traditional or classical Chinese medicine You can also check out my last two videos right there and right there


Good morning, everyone. I'm Dr. Shanthin Roy. I am a postgraduate trainee from Neurocon Short-Time Medical College and Hospital and I would be presenting my paper based on the evaluation of brain abnormalities and infants with myelomeningocene using magnetic resonance imaging. So, introduction, we see that spinal dystrophysm includes a highly heterogeneous group of congenital abnormalities that occur from abnormal closure of the neural tube, total identity at all, proposed a simple classification of spinal dystrophysm. Look, which was based on clinical findings and MRI findings. The closed form of spinal dystrophysm may be asymptomatic, but the open form is usually associated with several disabilities. Myelomeningocene is seen to be the most common type of open spinal dystrophysm and occurs from failed closure of the cordial end of the neural tube. There has been a significant worldwide decrease in the number of infants born with myelomeningocene because of improved maternal nutrition along with prenatal diagnostic tests and real time ultrasoundography. However, in those infants being born, depending on the location of the defect, significant neurological deficits might occur and patients have been found to suffer from lower limb paralysis, sensory loss along with bladder and bowel dysfunction. Myelomeningocene has been associated with multiple cerebral defects and these are directly related to intellectual and cognitive functioning. For example, hydrocephalus has been proposed to be the main cause of any cognitive dysfunction that the infant is suffering from. In addition, Wink et al had suggested that several other cognitive deficits might be attributed to Arnold-Carry malformation, which is seen in cases of myelomeningocene. There are few studies describing the forebred abnormalities related to myelomeningocene. However, most of these reports are based on autopsy studies, which might be suffering from selection bias towards severe types of malformation. We have evaluated cerebral abnormalities in patients with myelomeningocene, which the study done in children under six months of age in our present study. Our aim was to study and our aim of the study was to evaluate the pediatric brain in infants with myelomeningocene and determine the prevalence of various types of cerebral abnormalities in such cases. The materials and methods we used in the study were the study area was the department of radiative diagnosis in our hospital. The study period was from June 2020 to August 2021 and the study population consisted of 22 patients. The inclusion criteria was the patients referred to the radiative diagnosis department with myelomeningocene for the evaluation of their brain and the exclusion criteria where patients whose gargions did not give consent were excluded from the study. In addition, materials used where the brain MRI was performed with the 1.5 tesla G-signal, HD MRI standard, the patients underwent T1 weighted, T2 weighted filler and EDWI sequences in actual societal and coronal planes. The diagnostic criteria before we go into the depth of the study, the cari malformation are a group of defects with congenital cordal displacement, one of which is cari type 2, which is defined as a displacement of medulla or fourth ventricle and cerebellar formus into the cervical spinal canal and the presence of a small posterior fossa. Cerebellar hypoplasia was diagnosed when one or both cerebellar hemispheres were small with short but normally arranged fissures without any displacement through the foreman magnum. Brainstem hypoplasia was diagnosed when the brainstem had reduced societal dimensions and the anterior curvature of the points was flattened. Small posterior fossa was diagnosed when the posterior fossa had reduced societal dimensions to the corresponding deeply inclined interior. The partial agenesis of the corpus callosum was defined as an absence of a part of the corpus callosum, whereas corpus callosum dysplasia was applied when the morphology of the corpus callosum is altered. Corpus callosum was a descriptive term for the disproportionate prominence of the occipital horns of the lateral ventricle. In the results and analysis, the study consisted of 22 infants out of which 15 were male and 7 were female, the mean age was 2.5 months. Amongst the supratentrial findings, hydrocephalus was the predominant finding and it was seen in 16 patients. The enlargement of subarachnoid spaces was observed in 4 patients. Total agenesis of the corpus callosum was observed in 3 patients and all of whom had corpus callosum. Partial agenesis was observed in 4 patients and dysplasia of the corpus callosum was seen in 7 patients. A common finding was the presence of white inter hemispheric fissure that was observed in 9 patients and 5 of them also had corpus callosum abnormalities at the same time. Corpus callosum was observed in 3 patients and 2 patients were found to have polymicrogyria. Heterotopic grey matter was observed in 2 other patients and absence of septum pellucidum was observed in 3 patients. In the infratentrial findings, chai type 2 was observed in 15 patients and hyperplasia of the cerebellum was observed in 2 patients. Whereas hyperplasia of the brain stem was observed in 5 patients, a small posterior fossa was seen in a significant number that is 13 patients and cervical syrinx was seen in 1 patient. Now, discussion, myelomaningocele was seen to be associated with multiple cerebral defects as seen in our study. Mostly, however, in previous studies it was mostly done on autopsies based on autopsies. However, with the utilization of MRI, only some studies have attempted to evaluate patients of all age groups with myelomaningocele in our present study. After complete evaluation of cerebral abnormalities in children under 6 months of age, we found a spectrum of cerebral findings. Hydrocephalus was the most common finding as seen in also previous studies like just it all had reported that in a case series of 44 patients having myelomaningocele, hydrocephalus was detected in 27 patients. Now the enlargement of the lateral ventricle might be varied as a result of this symmetric and asymmetric dilatation can be observed. We could detect calligraphy in 13.6% of our patients. Anomalies of neural and migration usually causing seizures and developmental retardation have been reported in association with myelomaningocele. Just at all had described this abnormality in 6 out of 44 patients. In the present study, modules of heterotopic gray matter were seen in 2 patients. Now, interestingly, Hassan et al recently studied white matter microstructural abnormalities in children with myelomaningocele by using diffusion traction tensor tractography and found abnormal white matter development and persistent degeneration with increased age relative to control patients. Juronic at all studied using total cerebral volumes, neocortical surface area, neocortical thickness in children with myelomaningocele and subsequently reported about 15% reduction in total white matter and 69% increase in cerebral spinal fluid, but with no difference in total gray matter relative to the control group. Additionally, it was found that there can be significantly smaller neocortical surface area mainly in the occipital regions. Now polymicrogyria, which is very epileptic, has been reported to occur in 33% of patients with myelomaningocele. In our study, we could find it in only 2 patients. Now absence of septum pellucidum is also highly reported abnormality. It usually occurs along with abnormalities of the corpus callosum. In our study, there were 3 patients with absence of septum pellucidum. Out of these 2 were found to have concurrent partial agenesis of the corpus callosum. Now total or partial agenesis of the corpus callosum is seen to be a common finding as well. Just it all had recorded a frequency of 56% of partial agenesis of corpus callosum. Whereas Kaumira had observed partial agenesis in 50% of infants. Concerning infertorial abnormalities, the best known and the best documented in patients with myelomaningocele is obviously chiral malformation type 2. Just at all had found chiral malformation in 76% of patients. In our series, we observed chiral type 2 malformation in 68.2% of our patients. Therefore, the presentation of symptomatic chiral may vary depending on the child's age. Now decontration must be performed early for symptomatic chiral type 2 in order to promote a prompt and full neurological recovery. In 59.1% of our patients, this was found that a spinal posterior fossa was present. Brain, stomach, cerebellar, hypoplasia were other common findings and these can result in patients' neurological deterioration. One patient in our study was observed with cervical syringe. Just at all had reported that syringe occurred in all sections of the spinal cord and the size was seen to vary from small circumscribed cavities to large lesions. So apart from our study, we could see that apart from MRI, completed tomography and ultrasonography have also been used as alternative imaging techniques in the previous studies. Nevertheless, complete tomography has the distinct disadvantage of radiation exposure and ultrasonography is limited in the evaluation of posterior fossa. With lower resolution and operator dependence being a very vital factor in ultrasonography. So with taking all this into consideration, MRI is definitely the imaging procedure of choice. Limitations of our present study were mainly two things. First, we did not perform any volumetric measurements that would provide a more accurate characterization of our findings. And secondly, the study focused on structural findings of brain MRI and not the ultimate predicted neurological outcome, which needed follow-up of the patients. Here is a table number one, which shows MRI abnormalities detected in supratentorial compartment where we could see that the most common finding is obviously hydrocephalus seen in 16 patients. Here is table number two, which shows the MRI brain abnormalities detected in the intratentorial compartment where the most common findings were Kareem alformation type 2 seen in 15 patients. Here are some of the images of the findings seen in our study. This is figure one, which shows an actual T1 and T2 weighted MRI of two different infants showing hydrocephalus. This is figure two, which shows an actual T1 weighted image of an infant showing absent septum pelucidum. This is figure three, an actual T2 weighted image of an infant showing enlargement of the subarachnoid spaces as seen in this image. In figure number four, we see a sagittal T1 weighted image of an infant showing complete agenesis of the corpus callosum. There is no corpus callosum seen in this mid sagittal section. And in figure number five, an actual T1 weighted image of an infant showing nodular periventricular gray matter heterotopia and left lateral ventricle. In figure number six, there is a sagittal T1 weighted image of an infant showing cerebellar hypoplasia where the cerebellum is grossly reduced in size. And figure number seven shows a sagittal T1 weighted image of an infant showing partial agenesis of the corpus callosum with RNA type 2 malformation seen in the posterior fossa. Now in conclusion, we can say that brain imaging, especially with MRI at an early age, may be able to detect and characterize these abnormalities which are found to be associated with myelomeningosome. And detection of these abnormalities with proven neurocognitive effects will help to better determine the ultimate prognosis of the infant. These are my references. Thank you.