And now, stay tuned for the program that has rated tops in popularity for a longer period of time than any other West Coast program in radio history. The Signal Oil Program, The Whistler. Signal, the famous Go Farther gasoline.  I am The Whistler, and I know many things for I walk by night. I know many strange tales hidden in the hearts of men and women who have stepped into the shadows. Yes, I know the nameless terrors of which they dare not speak. And now for the Signal Oil Company, The Whistler's strange story. Ski master. With the winter carnival approaching, Sylvanas skiing lodge in the Rocky Mountains was a beehive of activity. Revolving about the handsome ski master, Carl Gordon. Carl was an American, but had spent many years in the Bavarian Alps. Following the close of World War II, he had returned to America and served a ski master at resorts on both coasts and in Canada. And now, Carl, you watch idly as gaily dressed sports lovers swarm through the large lobby, laughing happy people from all over the world. Suddenly, your glance falls on a middle-aged man. He doesn't look like a sports enthusiast, does he, Carl? You watch him closely as he surveys the lobby with a look of disdain. And then hurries over to a striking young woman sitting in the corner. You edge closer, Carl, straining to here. Dr. Prentice, you here? Yes, but in there I flew. I'm not yours. Yes, I left a minute I read about your skiing accident. And you came all the way across the country because you read that I'd hurt my ankle. Why, you darling! Then it's not serious? Why not at all? The doctor in the village mixed it up very well. Good. By the way, there was something else in the column. Yes? A mention of a romance between you and the local ski master. Well, I don't see how that could have been printed. No one here knows anything about it. It's a secret between Carl and me. A girl who has one of the largest fortunes in the country can have no secrets. No, I'm afraid not. But what about this romance? What's his name? Carl Gordon. And I'm in love with him. Carl Gordon? American, eh? Usually these ski instructors are from... Well, Carl spent a great deal of time in Bavaria during the war. Also, it's excellent. Yes, yes. Tell me, Clarinda, does your father know? No, I hope not. You know he'd try to stop it. But what about this Gordon? Who is he? How do you know he isn't after your money? Not Carl. I know he loves me, not my money. I hope so. When do I meet him? Right away. I'm sharing your... Oh, Carl! Uh, yes, Miss Rogers. Dr. Prentiss, may I present Carl Gordon? How do you do? I'm honor Dr. Prentiss. Dr. Prentiss has just arrived, Carl. He's one of my father's oldest friends. Oh? Have you come for the sports carnival, doctor? As a matter of fact, no. But I think I might remain. Oh, doctor, can you do that? Oh, I think I can arrange it. Then you shall give me away. Give you away? Yes. At my wedding. Carl and I are planning to be married during the carnival. Well, congratulations, Mr. Gordon. Thank you, doctor. I suppose you are very happy about this. Yes, indeed. I'm the happiest man in the world. Why aren't you, Carl? At last your dream is about to be realized. A wife with money, a big fortune. This is what you've been striving for all these years. Why you chose skiing is a profession in the first place. But things hadn't worked out as you planned, had they, Carl? No. Not after you married Frida, a beautiful country girl in Switzerland before the war. After the bombing of Munich came the news that Frida was killed. But that's all in the past, isn't it, Carl? Now you have a fine future as the husband-to-be of a very rich woman. And you're determined to let nothing spoil it. Later, when you meet Dr. Prentice in the bar, you try to avoid her. Care for a drink, Mr. Gordon? No, no, thank you, doctor. I sell them drinks. But surely a glass of Kirsch. Well, all right, doc, if you insist. Waiter, two glasses of Kirsch, please. I might as well come straight to the point, Mr. Gordon. What's this about you're planning to marry Clarinda Rogers? We're very much in love. No doubt you think so. I've known Clarinda all her life. She's been engaged to half a dozen men. Naturally. She's very lovely. And very rich. You're very unkind. Clarinda's impressionable, fickle. She was in love with a music teacher when she was only a child. Her father sent him away. Then it was her tennis instructor, a golf pro and a lifeguard. I don't see how this concerns Miss Rogers and me. She did not marry any of these men, Gordon. And she won't marry you? I think she will. No, she won't. Not if I can find a way to prevent it. And I certainly intend to. Doctor's manner is infuriating, isn't it, Carl? And you wonder what he's going to do? He has a great influence on Clarinda. There's no doubt about that. And he'll probably try to prevent your being alone with it. The three of you are at dinner when Mr. Wood, the manager of the lodge, comes to your table. You have nothing to worry about, Dr. Prentice. I've arranged for you to keep your rooms throughout the carnival. Well, that's very nice of you. I realize how proud you are. Oh, now, don't mention it. No trouble is too great for a friend of Miss Rogers. Thank you, Mr. Wood. You're very kind. Is everything satisfactory? Very. I must compliment you on the excellent service in spite of the crowd. Thank you. Fortunately, the extra waitresses arrived this afternoon. They look quite colorful. We always dress them in Bavarian costumes with a sports carnival. Starting in a bit early this year. Now, if there's anything you want, anything at all. Those Bavarian costumes are very effective, aren't they, Mr. Gordon? Well, yes, Doctor. They are, in a way. Oh, little Carl, that girl over there, the one with the long blonde braids. She looks like a real Bavarian, doesn't she? Oh, yes. Yes, I suppose she does. Oh, what's the matter, Carl? You aren't yourself tonight. Really? Well, I'm sorry. Perhaps I'm a bit tired. Tired? With a physique like yours? Nonsense. Tell you the truth, Gordon. You act as if you'd just seen a ghost. And you have seen a ghost, haven't you, Carl? The new waitress, the one with the long blonde braids. The resemblance is remarkable. A little older and thinner, perhaps. But so much the same. And you must know at once. Quickly, you excuse yourself and leave the dining room.  Later, you go to the back door of the kitchen where the waitresses will come out, restlessly pace up and down, remaining in the shadows. Finally, the girls come out in pairs, laughing and talking together as they go down the path to the servant's quarters. At last, she comes out, alone, the one with the blonde braids. You make sure that you aren't observed and then you start down the path after her and call softly. Frida. Frida. Who is it? Is somebody calling you? Yes, Frida. I calls you. Oh, no. It isn't. It couldn't be. Frida, be quiet. But Carl, it's you. It's you, my husband. I've found you at last. Hollywood, where the Whistler is produced. This was the week the movie folks awarded their coveted Oscars. Too bad there isn't an Oscar for gasoline. Because I'm sure signal gasoline would have run away with the honors for outstanding performance. Just as some actors become typed in certain roles, you may have typed signal gasoline for economy because of its fame as the go farther gasoline. But economy, mind you, is only the beginning of signal story. The important thing is what makes signals good mileage possible. The fact that signal gas helps your engine run so efficiently. For when your engine runs efficiently, you can depend on it to deliver an outstanding performance in any role. Quick starting, peppy pickup, smooth power. So if you want your car always to perform as if it had just won an Oscar, keep in mind that performance and mileage are like birds of a feather. They go together to get both. Get signal. The famous go farther gasoline. Just when your future seemed assured, your marriage to wealthy Clarinda Rogers about to become a reality.  But you're not going to let anything interfere and spoil things, are you, Carl? No. Somehow you must find a way out. Only you'll need time, won't you, to think things over and work out a plan. You stand almost petrified staring at Frida as she continues to talk. Then... But Carl, you are so quiet. Why do you not see something? Well, it's... it's such a shock to me, Frida. But are happy one, Carl? Oh, yes, of course, but I... I thought you were dead, the bombing of Munich. Our home was bombed. I lost everything, but I was saved. I was with a displaced persons. So long. You tried to find me, Carl? Of course, of course. I tried hard to find you. I rode everywhere, but no one knew of Carl Gruber. Well, I... I changed my name to Carl Gordon. But why? Oh, it's easier to pronounce. You know, more American. After all, Frida, I am an American. Yes. So now I am Mrs. Carl Gordon. Mrs. Carl Gordon. Gosh, Frida, not so loud. But why not? Well, I'm the skiing master here. They want only single men for skiing masters in America. But why? Well, it's... it's accustom. If anyone finds out we're married, I'll be fired. Now you wouldn't want that, would you? Oh, no, Carl. Of course not. You must act as though you've never seen me before. Can you do that? I will try. Good. And we can both keep our jobs and work hard and save our money. So that we can be together always. Yes, Frida. Always. You will come to my cabin, Carl? There it is. The one way in the back. Yes, Frida. But not tonight. I... I'm busy. But when, Carl? Tomorrow night. After dinner. Say, uh, about 10. I will be waiting. Good night, Carl. Well, one thing is clear. Frida hasn't changed. She'll never let you go, will she? But you have until tomorrow night to think things out.  But you know you'll have to be careful. Very careful. Make certain Frida doesn't see you with Clarinda Rogers. You know Frida's jealousy. The bitter quarrels in the past over your attentions to other women. So the next morning you carefully avoid Clarinda. But later she finds you on the terrace. Oh, Carl, darling. Where have you been all morning? Giving lessons. I've missed you. Well, now you have the company of your friend, Dr. Prentice. But I'm not so sure that he is my friend, Carl. What makes you think that, dear? No, Carl, you won't get angry.  What is it, Clarinda? You can tell me. Well, you're going to meet someone. My friend, as you call him, Dr. Prentice. He arranged this. Arranged what? For my father to come here. For the sports carnival, Dr. Prentice says. And father hates winter sports. Dr. Prentice just sent for him to try to break up our marriage. No one can do that. Where is he, Clarinda? Your father. Oh, you're not angry, then? Not at all. Oh, darling. It's going to be all right. At the first possible opportunity we'll drive into the village and we'll get our marriage license. Right. Now, Clarinda, shouldn't you introduce your fiancée to your father? Yes, of course, Carl. Father and Dr. Prentice, well, they're in the cocktail lounge. Come along, darling. Clarinda, I must say you've been keeping something from me. Had I known such places as these things, he'd be... It is fun, isn't it, father? And I'm so pleased that you approve of Carl. Yes, sir. You seem quite captivated by the atmosphere of Silvana Lodge, sir. Yes, he even surprises me on that score. I dare say, doctor. Yes, sir. Beautiful view out this window, don't you think, Clarinda? Very much like the barrier. Yes, father. The barrier. I understand you've been there, Carl. Yes, I have. You watch me from the top. No, I will go down, Carl. Here I go. Frida, you hurt. Stupid of me to fall. What happened? Carl, I will never be able to ski anymore. You can't walk? Yes, I think so. You will help me up, Carl? Yes, here. I'll help you. Now, look Frida, if you can make it all right, we'd better go back separately. There's a short cut just around that turn.  I understand. We don't want you to be fired. You are all right now. Oh, yes, Carl. I'm all right now. That's fine. This is my day off. I can rest.  That's a good idea, Frida.  Miss Rogers wants me to go to the village with her this afternoon. Anything too pleased, Miss Rogers? We'll be gone a few hours. We're starting to snow. There may be a storm. I know. We're going to use the sleigh. Oh, fine, fine. By the way, would you mind not mentioning anyone where we've gone? Of course not. As Miss Rogers doesn't want it known, she doesn't.  Yes? Well, I got a ski outfit and skis for that German waitress. Oh, Frida Gruber? Yeah. I shouldn't have done it. She's good. She's very good, but... Well, she's just not in shape. No. No, I suppose not. Well, she's just better. Take it easy. She's very reckless. There's no other country. I saw her this morning in... in Thundercliff... Thundercliff? She mustn't go near there. There are signs all over the place. Yeah, there are signs, but you may not understand them, you know. We phrase things so differently in America. Well, you just talk to her, Gordon, explain exactly what they mean. There would be no mistake. Tell her that you must not go skiing alone. All right. I will, Mr. Wood. I'll make it very clear to her. Yes, do with that. Thundercliff. Well, Carl, you've made one more step in your plan, Heaven. A reasonable explanation for the accident at Thundercliff. And the storm has played into your hands, too. The snow will cover your tracks. Make that night after you and Clarinda return from the village, where you went for a marriage license. You slip into Frida's cabin. She's sleeping a deep, heavy sleep. You put a pillow over her face. You put a pillow over her neck. You put a pillow over her neck. You put a pillow over her neck. You put a pillow over her face. All over quickly. When you look through the cabin for anything else which might connect you with her, the rest of your plan is more difficult. But you finally accomplish it. And two hours later, Frida's body, dressed in a ski suit, is at the bottom of Thundercliff. In the morning, when you go into the lobby, there's an air of tension, as if something had happened. The sheriff and a couple of members of the ski patrol are at the desk with Mr. Wood. Look in here a moment, please. Certainly, Mr. Wood. That German waitress. Did you talk to her about skiing alone? Yes, I did, Mr. Wood. I made it very plain. Well, she... She didn't take your advice and it's cost her her life. No. What's happened, Sheriff? The girl went over the edge of Thundercliff. Her body was shown at the bottom. This was obviously an accident. 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Find out his convenient credit term. Prove for yourself that today's best battery buy is today's finest battery, the new improved signal deluxe battery at Signal Service Station. It went very simply and smoothly, didn't it, Carl? The body of your wife, Frida, was found at the bottom of Thundercliff. The body of your wife, Frida, was found at the bottom of Thundercliff. The sheriff considered it an accident. And now nothing stands on the way of your marriage to wealthy Clarenda Rogers. You're helping the sheriff to fill out the accident report when Dr. Prentiss comes up. This is Dr. Prentiss' sheriff. Good. We need your help, doctor. There's been an accident. An accident? I'll get my bag with you right away. I know it's too late for that. The accident was fatal. That new German waitress was skiing over at Clarenda. Surely you don't mean Frida Gruber? Yes, doctor. That is impossible. The girl couldn't have gone skiing. She did. She was very reckless. Well, Carl here warned her. That's right, doctor. This girl had a displaced kneecap, an old injury. She heard it again skiing yesterday morning. She called me last night, said she didn't want the lodge position to know anything about it. Asked me not to mention it. Hmm. Oh, ski was a bad knee. Not only that, she was in great pain. I gave her a strong sedative. She couldn't have waken naturally before noon. Then someone awakened her, took her out to the cliff, pushed her over. I see no other explanation, Sheriff. But who'd want to do that? Did she have any enemies here, Miss Wood? Oh, no. No. She was a displaced person. She just arrived. She knew no one here and talked very little. Who did she talk to? You, Gordon? Well, we only talked on a sedative skiing, Sheriff. I warned her at Mr. Wood's request. She said anything to you, Dr. Friend. About anyone wanting to kill her. Of course, now. And she didn't seem to be the sort of girl who would make enemies. She was naive, sweet, so happy about being in America. Well, sure beats me. She seemed very anxious to learn American customs. Ooh. That reminds me. She made a rather amusing request. Huh? What was it? She gave me a letter that arrived for her yesterday. It's consistent. I have Mr. Wood. Put it in the hotel safe. She had the faint idea that everything was kept in the safe in America. Well, what's this? There's some light on the mirror. It is? Right here. It's apparently forwarded to her from some refugee association. I doubt it would be any kept. Well, I'll take a look. Here, madam. I told you that we have finally located your missing husband. He's working as a scheme instructor at Silvana Lodge in Colorado. Under the name of Carl Gordon. That whistle be your signal for the signal oil program the Whistler reached Sunday night at the same time. Meantime, signal oil company and the friendly independent dealers who help you go farther with signal gasoline hope you'll remember. Regardless of what gasoline you use you'll enjoy more miles of happy driving. If you drive at sensible speed obey tactic regulations and avoid taking chances. You may even save a life partly for your own. The region in tonight's story were Bill Foreman as the Whistler, Gerald Moore, Isabelle Jewel, Gladys Holland, Ed Begley, John Daner and her Butterfield. The Whistler was produced and directed by George Adrian and Carol Nick music by Wilbur Hatch and was transmitted overseas by the Armed Forces Radio Service. The Whistler is entirely fictional and all characters portrayed on the Whistler are also fictional. Any similarity of names or resemblance to persons living or dead is purely coincidental. Remember to tune in at the same time next Sunday when the signal oil company will bring you another strange story by the Whistler. Marvin Miller speaking for the signal oil company is Brooks starring Eve Arden who follows immediately of the most of these things. This is the CBS Radio Network.


Dear students in this module, we are going to look at the workflow for structural modelling or structural prediction of proteins. As you already know, homology modelling can be used to predict the structure of those proteins whose structure is unknown but their sequence is known. The process works by comparing the sequence of this protein which has an unknown structure to other proteins whose sequence and structure are known. By comparing the sequences, we can talk about the possibilities of similarity in the structure of these proteins. So this is essentially the theme of homology modelling. So let's consider how the workflow or the flowchart of homology modelling works. So first of all, you need to start with finding the DNA sequence. So once you have the DNA sequence, then you can find the ORFs. As you know, there are six possible ORFs and then you find the longest ORF which is then used to translate the protein. So by looking at the ORFs and then the translation process, you can come up with the amino acid sequence or the primary sequence. As you know, the proteins have the primary, that is one prime, secondary, two prime, tertiary, three prime and quaternary, four prime structures. Next, if you don't have the DNA sequence here, then what do you do? So you cannot translate the DNA sequence into the amino acid sequence. In such a situation, you have no choice but to look at the protein that you have and try to sequence it using admin degradation or mass spectrometry. So in case you don't know the DNA sequence, you can always go after mass spec. Now, since you have the sequence with you for your protein, you can search for other proteins in the databases such as Uniprot. So Uniprot is a sequence database or SwissProt, which is also a sequence database. So you can search for your protein within these databases to find other proteins and those proteins should have a similar sequence.  So the blast algorithm will give you the best or the closest sequences from the database when compared with your protein. Okay, next. Now you have your protein sequence along with similar proteins from the database, yes. And all you have to do now is find out which proteins have a structure which is known as well with them. For instance, if you found four different proteins from the database search, you need to go and find these sequences from the protein database or the PDB. So let's say all four of these sequences had a protein structure for them in the PDB. So in that case, you are in a good position to perform homology modeling because the 3D structure of all these proteins is known, right? But it can be the case that one of these proteins does not have its structure which is known. So in that case, you can leave that sequence out and only perform homology modeling for those sequences whose 3D structure is also known. So you move on to homology modeling. Remember that the only requirement for homology modeling is that the structure of the proteins is known. So the proteins that came from the blast should have their 3D structures also with them. In case they do not have the 3D structures with them, then there are other methods such as motif recognition in which you search the secondary structural databases. Sometimes it's also called pole recognition. You can also do ab initio modeling which is a complex method towards determining the protein structure. So overall, there are three different strategies for predicting the structure of proteins. The first one is the homology modeling which is the case in which you have other proteins whose sequence and structure is known and then you come back to your unknown protein and you try to predict its structure. If that is not the case, you go for the motif or pole recognition and if that is also not possible then you go for ab initio modeling. So next we will proceed to specifics of homology modeling that is the seven important steps that are there to perform homology modeling towards predicting the structure of proteins. This we will see in the next module.


I do not want to dig so much into the past but you knew I had to ask this. This time you were involved in this particular kandolia.  Is this a moment of regret or a lesson? How do you feel right now when you look back? I should regret but let me tell you the reason why I don't regret is that had I not told my side of the story then somebody else was going to do that for me yeah ah okay now you know Anita I really would like to know have you ever you know met Milichebi and just spoken to how she ever contacted you after all these amaa how how how is it what's up guys and welcome to yet another episode of bars with stars right here on spm bars guys if you haven't subscribed just yet see do you know gojianini see subscribe uh i'm gonna hesitate please subscribe sendio all right guys now when you see me here you know i'm hanging out with a star and today i am honored to be hosting a 22-year-old she goes by the name Anita Suina and other than just that you know she focuses on you know talking about environment issues and the most of all is that this 22-year-old is vine or rather aspiring to be an mp of kajado north see by this is the second time like it is the first time you came we were just talking about environment kupanda meaty but right now we are talking about a different conversation karibu sana spm bars it's like home to me i mean yeah yeah karibu tena na tena let me ask you where do you get this confidence to do all these things you do very vocal on social media as in as as a 22-year-old there's some things you talk about and engage in that are just different where do you get this confidence now first of all i don't believe in fear if you fear then you're not going to pursue what you want everything nowadays requires courage even if it's that thing that people think it's simple so for me i've always been a fighter i believe in fighting for myself fighting for my space and fighting for people just making sure that anything i do involves fighting for people as well so yeah you know that way you need courage so for me it's not an option yeah have to be courageous yeah there's no other option there's no other option you know let me ask you have you always been passionate about you know plans and just a breath of fresh air amma is it something you you know you acquire during kampu amma you know i don't like lying to people that oh you know i started planting trees when i was three years so that's a lie yeah i even never saw value in trees i never like imagined that one day i'd even be speaking for trees speaking for the environment and all that but it's something that i i picked up yes maybe because of the environment that i grew in raised by my grandfather at some point and he really used to value trees he had some small forest that he used to make sure it's protected and when he passed on things changed and all that but still at that point i still didn't see the sense you know you're just a small girl and just because babu says this doesn't mean you see the sense but when i grew up i joined our campus i was in the scouting club so jia fanki defi it was of course the head but at some point i was the chairperson of the scouting club so at this point we had a lot of community work you know as a scout you just have the community even if it's picking later in school and visiting i don't know the needy people outside the school and all those things so when it came to tree planting um few people used to take care of the trees so i had to do it because i'm the chairperson so i'm just doing it because it's bofanya patron at a kafirika and all those kinds but after high school i was actively engaged in politics so during 2017 campaign i met my mentor who's erik masanda so for him he trained he nurtured young people to recover their passion so he taught me about the sustainable development goals that time there was no to poverty and zero hunger i wanted to focus on that but then again just reading about them i came across climate action so i realized it needed more attention and growing trees was part of it so i just started like i shifted completely from other sdg and focused on that kind of climate action so to me i i termited discovering my passion because sometimes you can discover your passion even later very true i mean you you actually discovered your passion very young to be honest if you are 22 right now how long have you been doing doing this you know in terms of environment i covered my passion on of 17 that is in 2017 yes but i started actively engaging in 2018 in 2018 then now you what most people might not know but you went to a media institution to study journalism yes i went to a media institution to study communication related costs if they are in corporate communication at multimedia and i remember by the time i applied you know we used to apply in high school so i wanted to just do anything in relation to communication but when i joined campus i was already focusing on conservation but then i also realized that there was a gap you know because i'm trying to do something yeah there is that unique thing there is someone who is doing what you do yeah that everybody is unique in their own way very true so i realized in conservation uh we have this narrative that maybe i have to go to a school a science related school study environmental science and then be a conservation so i decided um no now if i'm going to do uh activism and advocacy i have to change this narrative that i can study something different and still take care of the environment so that it just because this is my home this is the planet then i have to take care of it so it doesn't have to be a career so that's a doctor and add someone in arts and entertainment someone in a totally different field yeah still value conservation value conservation wow okay now you see when um wangari matai made her so rest when she was actively you know advocating for conservation of environment and you are pretty young i believe so and i just read about her in both and you know we just you know read her like any other hero yes yes yes yes so when you decided to go this route did it at some point um because you know people started comparing you to wangari matai you know even abel mutua featured you know you are you know on his stories yeah and just mentioned that you you you're following that foot foot path rata and wangari matai was a big deal and you are there trying to fill those shoes did it come to a point that you started filling the pressure eh nani kama i'm comparing myself ama eh but i have to put more effort did it come that time you know for me i never allow that to happen why because for me uh wangari matai is not a competition but a role model yeah you know even schools outside even activists that we meet outside tell us that you know how do you feel that wangari matai was from your country yes so it's something that um you know when the moment you join environment conservation you will never avoid wangari matai i mean if you try to you will not so i i look at her as a role model okay as someone i follow her footsteps so sometimes when somebody call me wangari matai as much as it's something i really like or it's something uh you can feel good about then i also think about the match that she did yeah it's either you have reduced wangari matai to me yes who has not achieved the match she achieved yes or you have um so to look at it positively you have at least seen or the the same your potential and the same spirit yes yes so for me i look at that as um as a challenge that she was a fighter she did so much to conserve the environment and she went through a lot so anytime i'm going through the same uh the similar issue with her or so i will always look at how did she overcome this and if she did it then i can do it but try to avoid the pressure as much as we have the pressure but i never look at um trying to be like trying to be like her but following her footsteps yeah okay so what is that one moment you know during your your shenani ganzote activities zoteza to do with the environment since you started what is that who is that one person you've actually met in your line of work and you are you were in oh like you were very happy to actually interact with that person um last day in november we traveled to the uk for kof 26 and i was invited personally to go and have a meeting with some of the activists with two u.s. senators that is our senator jeff mackley and ed mackley okay and i was the only one representing africa at that time and i was the only one representing uh pastralist communities and outside when you dress like a masai you you are indigenous community which yes we could be indigenous communities so i was representing the minorities representing kenya representing africa in a small meeting of just four activists so for me that was really uh something um that made me so happy it's something i didn't expect considering i really didn't look for them it was a meeting that they look for us yes and how they were even listening to our story yeah i mean that was everything to me in conservation that's really great now you are now getting into politics and back story you just mentioned that in college there's a time that you got into politics what were you vying for and you know how was it now in kampu i don't recall that in kampas i was i was actively involved in politics i never died oh okay uh i wish i knew i'd have tried because the challenge that i was running away from that time is my biggest challenge right now in politics um i used to be actively involved campaigning for people yeah all those things but at some point i was also elected as the secretary general for kenya university female student leaders association that one the campaign was not really tough because it didn't involve much resources okay printing out posters no it was just up here online campaign so that's why it was easy for me and kampas politics uh what didn't look easy because the same way we struggled with resources out here yes the same way in kampas especially when we had the delegate system i mean i joined kampas on the delegate system was also being introduced yeah so this one you have few people and i i used to see how my friends who used to buy just dish out a lot of money yeah so as a metaphor am i going to get all this money yeah and we used to have our politicians funding our student leaders but i didn't think it was gonna be easy just me looking for someone just to buy my idea that i want to buy for such a position yes it was a challenge that i tried to escape yeah so you want to mean that the hesitation that was there to join politics was just because of the finances and the resources that were needed so you still had the compassion the delegate system is but you literally the highest bidder yes and you could give money today and tomorrow your opponent is just waiting to give out you know you could go out five thousand children and someone gives out five thousand five and then you i mean a hundred percent yeah so it's the highest bidder and i was not ready yeah for that i was scared i mean i cannot wait to actually just talk to you and ask you what makes you feel ready now but now before we get there yeah now you just announced that you want to buy for an MP seat which is quite a big deal and you know people are like oh my god she's 22 years old she's she has the confidence to do this how did that come about because i made this announcement on our team 21 yes so when i even turned 22 many people still say i'm 21 yes i remember in 2020 i had made a similar post that i was going to buy okay yeah i think i had seen that uh and i pulled it down because at that time covid was here and we were not even having online classes in our school okay so buy for an MP seat to be on the safe side you have to have a degree okay so i pulled it down and i gave up i knew because we were told that we're going to graduate in 2022 yeah so that means uh i know going to do this and looking at the roles of an MP and all that i really didn't want to you know you also choose what you feel you're comfortable with so i wasn't ready to buy for an MP seat of course so at this time i i totally knew that this was not going to happen anymore and i felt so broken so i knew maybe 27 or or in future yes so when we went to school and luckily we had a speedy coverage of the okay syllabus and we were able to get done in school so at one time i was seated in west land so i was just sitting fish somewhere and i thought uh it's too late because i was budgeted in december 2021 it's too late i think our people have already campaigned i don't think i'll catch up then i went to on kanwa i designed a poster yes and it was enough for MP Kajadonov 2022 yeah so i looked at the poster uh my friends were there so we were just discussing politics with my friends but they didn't know what i would do yes so i just designed a caption i was like okay and then i just posted it yes and i just posted it like it was just that way but i knew deep down in my heart i will still go for this now that i have this ticket yes so when we got to when i slept and the the next morning i woke up people were sending me screenshots and my mom is calling me yes my mom was like your skyrocketing i was like what's wrong because i i i was not even remembering that i had made that post yes so i didn't expect much pressure from the post okay so my mom sent me a screenshot from citizen digital 2021 year old environmentally set of i for kajadonov and now my friends are calling me why i didn't tell them yes and i told them point blank right now everybody has opinion to be so unfair for me not to listen to some of your opinion but i need for gonna tell you i will still get a not this time of course just try next time and i didn't want that i told them this is not the moment i want to hear that i even told my mom right now you just you should be telling me well done you will make it i just need those positive messages yes just that way and now i knew um now this is going to happen yeah you know i would really want to know like how exactly how your mom's reaction was how was it now just take us through the the poster citizen digital then the phone call how was it you know what's happened is that uh i graduated okay and when i graduated a lot of uh some of the blobs also picked up that anita finna the environmentalists have graduated in ola so there was too much attention on the media of me graduating so two days later this is me announcing i'm fine yes my mom is looking at all the attention it's coming with she she wasn't surprised because at some point i remember she she even tells me that that my grandfather used to say oh this grandchild of mine will be a leader one day he was also a leader okay and i have an uncle who's also a leader so my mom was not like really shocked but she she just felt it was too early and she was wondering how i'm going to do it so she felt like maybe i'm not serious or if you're serious why are you doing it right now yeah and she doesn't like when i have stress or when i when i have pressure so that was the big stress for her okay and now getting relatives asking her questions if if she knew about it yet she really didn't know about it yeah so i told her even for conservation she didn't want me to to start early she used to tell me how to finish kufas so i told her mom we have this culture where you have to let me wait for myself i have to start when i feel i'm comfortable so i do it fast and then i let them know so then actually when she was sending me the screenshot she was still uh not okay with it like she wasn't sure if i'm going to be okay with it yeah but after a few days she really gave me support okay she commented and she'd be like congratulations she didn't call me when she was on the call she just encouraged me yeah for my mom i'm used to that like she will start but when she realizes oh it's it's something i'm okay with that i'm comfortable once she realizes i'm comfortable then she'll also be comfortable yeah what about you know the people who are close to you who are a bit older than you what were their sentiments um they were excited okay imagine and i was so happy because we are so proud of you how did you think about it i even have friends in also in politics and maybe even if they had maybe they felt like for them they never felt like it was too early maybe they just felt like will she handle it yeah but still they will encourage me they will feel like uh they'd say this is so inspiring and all that yes yeah okay and then you decided the political party that you want to go for okay and of course the leader we all know is the current deputy president of kenya so i would really want to know the first time you met the deputy president have you actually you've met of course you've met him the first day you met him how was it uh fun enough we met the deputy president through forums okay not like we've ever started yes not like you know having one on one but in forums that i have actively participated he may not maybe have remembered even because he handles a lot of people in a day of course but it i was so lucky that when he was coming to kajado yes for the rally yes i was also around and that was my first time to even appear to the public yes so i had not really gone to the public to seek votes i just made this post and we are now sitting down with the team strategizing and in the process i get all the deputy president is coming tomorrow yeah now the nature of campaigns is you have to be so aggressive nobody like in some situations nobody will say you are a lady you also have to fight and yes so i remember that time we were rushing to the stand you have to rush to the stand so you can be able to speak when other aspirants are speaking so the first top when i went there some of the people blocked me and i told them i'm an aspirant so they told me mca's are writing their names on the other side i told them i'm not a mca aspirant i'm an mp aspirant because mp aspirant was speaking since you are a few and mca that you are usually many and sometimes maybe there is no time i'm an mp aspirant but this person didn't believe so i went to some sitting member of parliament and told him you know i'm the youth here we are the youth here i have to speak because youth also is this crowd yes and they had to allow me so when i spoke yeah now i had to speak in the in the uh in the remaining uh the remaining stocks yes i was also trying to read the mood of not only the deputy president but the leaders around yeah and they really appreciate that and i felt at home i felt like this party is accommodating young people as much as i redone to the party uh in different aspects including their economic model i i felt like now this space is good for the youth and the right place so was there a point that you had a conversation with the deputy president um the next day in i went i went for the rally in kasarane yes because the the day when we heard the rally in my plate a friend of mine called stagana we used his vehicle he came with his vehicle you know if you don't have a vehicle it's hard for it to survive for sure and also a specific type of vehicle you have a sunroof you know you can just i mean come out and see how you consider so the next day they were having a rally in kasarane and he's also vying in kasarane so we went to support and just around the car and i didn't know that deputy president could recognize me so i was like so you know kwaapa and then i kind of got and i was like uh then this is really nice like i didn't really uh i was not thinking you were going to remember me yes yes oh that's really good to hear how did it make you feel you know just him actually mentioning your name and recognizing that she knows he knows you yeah i really felt uh i felt good the fact that uh he i mean he and those many people yeah so even if he remembers you today and forgets you tomorrow that way that he remembers is really is really important and it makes you feel like um you're the right place yeah and for him he's really i've had space for the youth yeah he likes youth and that's why most youth still read on it with him so you went ahead and met your competitors there you know the people that are the ones that are aspiring to be MPs in kajado north as well how was it because you see this is not something that we are used to seeing competitors sit down because again they are older than you they're like your dad you know the age of your dad how was it the moment i decided to buy i told myself my name and fear show never yes appear in the same sense yes so for us what you're trying to do is you know we are having party primalism and we are trying to show people that we are not just preaching peace but we are also you know we are also trying to do the same um we we are about six candidates in kajado north five of us meet almost every day i don't know about the other i may not talk about the other but the five of us we we are friends we talk we even agree so because you know after nomination we will have one candidate for sure and we have to support whoever it is you know so we try so much to make sure that we are not we don't even have any reason to fight we are children of the same house we belong to the same party we meet um we meet sometimes just have coffee and even discuss things just about ourselves so for us we are trying to change the culture of politics where if this is your opponent they have to be your enemy no we're just political we just have differences in politics just that maybe i'm buying in your mind but we don't have that enmity at all and i really like that the moment we sit down together i always feel relieved unlike when you know before i sat down with them out feeling the tension and they also are they don't despise me being young yeah uh that's something i appreciate that we could go for campaigns and they will really say uh what's your name to taonga you know like what's your name and all those things really makes me feel good so it's something that we are trying to do changing the culture of politics that we have and we have to be enemies and you know one thing i realize people fight not because the politicians fight uh we don't fight we just show differences and people start fighting but when you show love and you show and you show that we are in one house that if one wins we have to support them then our supporters will support us peacefully so that my people support me your people support you but not having to to have a physical fight i love it now um of course aspiring to be an mp requires resources like we mentioned earlier it requires finances and i tend to think you know you require a couple of millions yeah like 15 and above yeah depending with how you want to use the the resources um where where are you getting where are you planning to get the finances to do this anita where i think my candidacy is just there's a there's a fresh in college in that phase dependable first of all let's start from there it's not easy yes it's not easy at all i'm not having resources but i'd say as much as i don't have even a quota of that i get support from people like i just be seated and maybe someone sees my work and says i want to do you maybe even 50 posters yes i even have someone the other day who who did business cards yes took a photo from my from my subs data made a poster and then sent me photos of business cards wow and then someone is calling me from from keterian uh who had my number that have seen me also small business cards and i was not even aware so it's wow they are like just campaigning on your behalf on ground and the same person actually just knew me i think uh from the campaign ground and all that yeah and anytime there's an event he has about an event he will always go do you have a car can i come and drop you with my car i mean wow these are people i had not even like interacted with before yeah but on the on the looking at the other side because really much resources are needed um a few people here and there someone will sell do you tisha someone reflect us someone uh i'll do you different yeah that's so you're entirely relying on yes help that you'll get and well wishers you know i'm looking at most of my you know i'm i'm in a very tough situation right now looking at my opponent these are people who've been fine others have been i even sitting mca yes who've been there for 10 years and this means they have a lot of resources others have just been there uh even people who've been vying before are in a better position than me because they usually say at iakwanda niako zagina and for me that's not me i want to win you know i mean this to win it so telling so you have to think about the resources you have to have first of all kila mta kuji on the level now so that's a really big yeah because now look at someone like boniface mwangi he's he was an aspiring empi as well but he did not have that you know liquid cash to give people and people were telling him boni tuneza kumotia lakini hauna do imagine have you had such yes and interaction care and it's so sad that even my age meant now who knew that i just completed campus the other day one expect if you mean when i hand out here wow so am i going to convince those women there who don't even know me who don't understand about you oh is it you already knows me that i have to convince so now days um hand out to the panda be what's only talk about 50 bob 100 yes so now you just down and you're like yes and then we have this um thing that people like to say so this is a narrative that has been put in our heads yeah because you know someone mama so next time when someone is by they'll have to maybe even launch and all that you can imagine i even had there's a place where people are being given 100 shillings they're about they're about 3000 people yeah i know a thousand people and they're given 100 100 100 you know how much that is that's a lot yes you know and so someone will come and say so some me are too but they will not see the point of what all our car is not going to go yes until we give money oh wow now you have to check your phone and give money or everything that you have you have yeah so that you can be allowed to leave yes and it's not people don't care that maybe you are a lady or you're young or you've not worked even if you're a toddler that's not they don't even tell you that's not their business yeah yeah oh my goodness i'm really trying to avoid that yeah quality so that any amount that i spend actually maybe goes to a project or goes to something that even if i don't win i will still look and say look we did that yeah wow now apart from the the finance aspect or rather the finance challenge is there any other challenge that you've encountered yet um i think the people have accepted in the young person okay it is an advantage but also some openings from even other parties and even like one in our party will always use that to maybe think to maybe tell to tell the people yeah that's onim dogo that's why my slogan is not too young to lead yes because if i've been able to handle our organization staff and other projects before yeah i don't think it's it's about age or something it's about the willingness to deliver to the people yeah and also i'd say another big challenge apart from resources that's the main challenge resources and people is claiming that you're young which is an advantage but i'd say youth youth don't support their own i used to think so and it's not only for me yeah i'm sure if you have an interview other youth they'll tell you the thing yes and they don't vote yeah too sad to say they vote but women vote more than youth so if you want like if you are a youth and we are we are looking at youth leadership it means you have an you shall have an army of youth behind you yeah i mean but what i see even in what's happened i mean as a youth you have a right to ask me what i'll come and do for you yeah but they put youth in a corner that they don't do the same to these people so it shows you that they are not even interested in your leadership they're just there to maybe frustrate you kind of something not to really ask you because they're interested in us which is a big challenge and i think that's where we fail someone was telling me it's something that we really need to do but we still have some hold up but i'm sure it's something that our youth can slowly change and learn i personally want to create a leadership where it's not just me being a youth but it's about me sitting down with youth and asking ourselves me need to find out what do we need to do for the constituents so that when i get there you hold me accountable it becomes asked it becomes a youth leadership not an it has leadership with a youth so that way we are able to even deliver together you know that's the kind of thing that i only wish yeah okay i really hope we know we can just work towards that end and just achieve a better connection with our fellow youths because now it looks like it's a problem but uh you know now you know they say when a woman gets into politics yeah they become uncontrollable it's so hard for them to settle down and you know just get married and have a family have you gotten such backlashes such backlash ama and where personally do you intend to settle even here at your main fear women and i don't know but yeah i personally intend to settle one day of course i would want to have a family just like other people maybe not now yeah you know before i even decided to join politics and all that maybe there were that years to even have time like i did here yes but right now but yes i intend to yes aya mamu tenei mendei ki change tenu tenu kiyongezah miaka kathati apa na wati kwa kathati five kidogo tenei wati kwa kafoti this space comes with a lot of responsibilities and you know in a family yeah it's a woman who has responsibilities yeah so i i'm looking at at least trying to also achieve for myself yeah have my own goals have my own like just get to where i want to be so that's when i even settle down you know settling down i'm also bringing something to the table so that i don't say i'm the table yeah yeah yeah yeah but let me ask you know with your 22 year old experience do you feel like men are intimidated by you know women who are in higher positions than them why do you think so yes because um you know in my like in my previous relationship yes um i was not even doing much oh it's previous is it the one that you post hand for us the guy on social media so now it's previous well noted yeah it is previous ehe hi it has been long you know for me i i don't when i need when i'm doing some of my things i don't like pressure the only thing i need is space to be able to achieve my dream and for me i've always tried to be that person who's chasing their dreams because i believe i used to know that men appreciate women who are chasing their dreams for ground so like for me it's not necessarily financial support yes but just that support of keep going and all that so it got to a point where now i am requested to stay back home because conservation is not paying me but i'm looking at this something i it's it's not it's not like i'm doing it for a living so if it's not paying me well and good i even put my resources there yeah but this is me leaving my dreams i am happy i like it as a as an environment of activity as an environment to advocate speaking speaking for all these environmental injustices is something that i've always wanted to but telling me to stay home that because you provide anyway and that i can just sit home and wait for it made me realize that uh what i normally hear is true yeah it could be maybe that was not the reason but for me how i view it that was the case i feel like if because saying that you provide and that that i should stay home meaning i should not proceed with my life in any case i can provide for myself yeah maybe you feel like i can't be controlled or something of the thought yes and i don't want to lie you know we live in a society where most negative things are said about men but for sure we have good men out there for sure we have men who still empower women empower women even if they are not maybe their girlfriends or their wives or something so we have people still empower them not necessarily not just financially yeah you know that also you know living home with uh you know living home you're going out for tree planting yes i know it's not paying me but i know this is what i love doing it what i've decided to to do yes with uh you know go make just go make yourself proud and a word like that is better than is if it unafanya as a kulepi and coming back home too ome toko kwenje watu ana kufi if everybody's proud of you people are just telling you to keep doing your entire in many people and then getting home to search you even get demoralized yeah like you know what love you but me first it is what it is and i agree it should be it should be always you first and just your happiness yeah because at the end of the day you cannot peg your happiness on someone else any that is the last thing someone and you know if i'm not happy yeah this relationship can't it will not be happy yeah and it's not like i'm demanding too much i'm just asking that i just follow my path yeah i just do what i want to do and i mean you see i actually see that men no support there women in what they love doing it actually gets to be a success and just helps the family at the end of the day how do you feel when your girlfriend or your wife is making steps out there yeah you should be proud of you know hi instead of being intimidated you know no kind of yeah but like i said these people are few we have good men out yes i have seen people i don't even know even online yes even people great leaders like uh the obama and all that we've seen them yes so it's not like men are not there it's not like we don't have men who support yes okay okay now anita i i don't want to dig so much into the past yeah but you knew i had to ask christia so this time you were involved in this particular kando let's call it a skandolia and um with this particular comedian and you came out and and just told your side of the story very confidently when you look back is it a moment of regret is it a moment of a lesson or how do you feel right now when you look back i should regret but let me tell you the reason why i don't regret yes is that had i not told my side of the story okay then somebody else was going to do that for me yeah you know sometimes my even my friends or people there's someone who even stopped talking to me after me when i met okay let me tell you then you know the way people repost instead of blogging yes i should inform to her too you know and this person is like you know because you first should ask me why did you yes you do it yeah so like i'm as much as i was young i got because uh i i am always ahead kindogo toki so i didn't want to nobody will you know people you are in this field yes you know nobody will want to just come out in very true very true but at that moment i think like i say as much as sometimes i may not agree with edga yes he taught me one thing okay that time for me to fit down and do that interview yes he showed me that it was planned to be done in a different way okay and you know the culture of online all the space that we have now this the first story is always right so had i just kept quiet in the name of at his silence to you if you don't talk to you there is nothing to you mean i don't mean i had to and i am as much as they thought sometimes maybe i may not agree with someone edga taught me at that time yeah okay now you know anita i really would like to to know have you ever you know met mili chebi and just spoken to how has she ever contacted you after all these amma how how how is it you know i don't know why i'm trying to avoid uh talking about yes her at all yeah uh because in 2019 when i clearly if i do that today yes because there are things that she puts out there that i even didn't know about myself okay and had i done what she did it would be worse on the side so i don't really like talking about it i don't have bad blood with her even in the salon when you used to do my hair before we used to do her in the same place we've met in places she said hi to me so it's fine yeah i mean okay and i really hope you know in future that relationship can be meant at the end of the day or rather just i mean i didn't have a problem with anything at all yeah i'm i'm someone even my team member can tell you i'm someone who gets mad yeah in the next minute i talk to them and you will not even believe that yeah all right anita i mean these are it's called a life experience it teaches us lessons what what did that scenario teach you yeah on your story on your story on your story taught me and i don't i don't even like to call it anymore yeah you know in this life there are stages and there is a path yeah that you may you may try to run away from it but maybe that's how it was meant to be yeah so i look at it as a path that i was walking through and maybe there was supposed to be a hill at that time yes it's normal it's normal it happens to everybody yeah even to the people only that people some others are not ready to talk about it you know or they are not known so we don't even know what you know i mean but i get it anita now i would like you know to just talk to your fans your people tell them something what is it that you you're up next doing just talk to them um i think the only thing i can tell people i like to remind people to go for what they want uh as long as it's something that is going to be your life something that you feel is going to make you better just don't be scared and i don't believe in procrastination and postponing because the what you'd have done between now and when you intend to stand to start is much um we're also having projects this year for conservation in the organization uh that is reviving or continuing with our ochas uh for schools program where we plant fruit trees and we also plant indigenous trees and schools so anybody who is interested uh in supporting or joining the cause from whichever part of the country we also have coordinated so you can be part of our organization in mombasa kericho bomet and all those areas um lastly if any of my constituents will watch this i hope that i i am actually asking for your votes come april during the nomination so that you can also be able to forge ahead together i will be presenting my manifesto soon that will come more detailed so i am doing a manifesto based on the problems of the people not based on the decisions i'm making in health and i hope when this time comes you're going to support me so yeah you can also support our conservation project via our tilt number which is 54 83 54 1 that is five warriors kenya if you want to support my political bid you can just maybe take my instagram i can share with you the context yeah all right anita that was beautiful thank you so much for talking to spm bars and just sharing with us what your thoughts are you know your journey as well and just your projects that are coming up as Santestana now guys that was the 21 year old anita soina who's an aspirant of kajado north as a name p guys please watch out for anita check her out on her social media pages just see what she's up to what is she doing and just support her because you know she's young ambitious and very aggressive and i mean she deserves your chance as well now thank you so much guys my name is miss kitingi and until next time this was buzz it starts right here on spm buzz goodbye


Well, hello, everyone, and welcome to another episode of Resiliency Radio with Dr. Jill. Today, I have a special guest who I have long admired, and this is our first official meeting, but you're going to hear all about gut health and why the gut is connected to every single organ in the body, and if you're suffering from chronic disease that seems totally far removed from the gut, heart disease, cancer, auto-immunity, inflammation of any type, you're going to want to hear this podcast today because we're going to dive in as to how the gut is connected to all these things. So Dr. Gundry, welcome, and thank you so much for coming on the show. Thanks a lot, Joe. Great to be here and love to talk about the gut. Yes, me too. So let me introduce Dr. Stephen Gundry. He's a founder and director of the International Heart and Lung Institute in Palm Springs, California, and the Center for Restorative Medicine in Palm Springs and Santa Barbara after a distinguished surgical career as a professor and chairman of cardiothoracic surgery at Loma Linda, one of the blue zones, right? Loma Linda University. Dr. Gundry changes focus to curing modern disease by dietary changes. He's the author of New York Times bestselling book, The Plant Paradox, The Plant Paradox Cookbook, The Plant Paradox Quick and Easy, and The Longevity Paradox, along with national bestsellers, The Plant Paradox Family Cookbook, The Energy Paradox, Dr. Gundry's Diet Evolution and Unlocking the Keto Code, and more than 300 articles published in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmunity, and many, many other things. And we're going to dive into that today. He's the host of the weekly Dr. Gundry podcast and founder of Wellness brand, Gundry MD. He lives with his wife Penny and their dogs, Ann Palm Springs and Monticello, California. The Ceto California. Thank you. Thank you. That's a tough one. So welcome. Welcome. And what an amazing career with all those books and then the previous career cardiothoracic surgery. So I always love to ask my guests, what was your journey to medicine and how did you really transform into this integrative holistic doc where we look at root cause? Tell us your journey. Well, real briefly, I decided to become a doctor after reading a book in fourth grade in my public school library called All About You and I decided to become a doctor that day. So I had, I went undergraduate at Yale back in the Dark Ages and in those days, we were actually able to design our own major and it was basically you did a master's thesis and I chose to, my hypothesis was you could take a grade A, manipulate its food supply and manipulate its environment and prove you'd arrive at a human being. I actually defended my thesis and got an honors and I give it to my parents and went off to become a famous heart surgeon. So I eventually wound up at Loma Linda, California and Loma Linda University Medical School and I was a famous heart surgeon who among other things, I was famous for xenotransplantation, pediatric transplantation and operating on people that nobody else wanted to and there are a few idiots like me and so back in the late 90s, I was referred to gentlemen who I call Big Ed in all my books. Big Ed was 48 years old. He had inoperable coronary artery disease. He was from Miami, Florida and he, all of his blood vessels were clogged up. You couldn't put stents in them. You couldn't do bypasses because there wasn't many places to put a new vessel and he went around the country looking for idiots like me to operate on him and everybody turned him down and I'm kind of on one of those stops and he spent six months looking for somebody and he finally wound up in my office after about six months and I looked at his angiogram, the cardiac catheterization of his heart from six months earlier in Miami and I said, well look, you know, I don't want to break your heart but I agree with everybody else. There's nothing I can do for you. They're right and he said, well look, what you don't know is I've been on a diet for six months time and I've lost 45 pounds.   Why don't we get a new angiogram? Why don't we get a new cardiac catheterization? Don't get your hopes up. Okay. So the next day we get an angiogram and in six months time, this guy has reversed 50% of the blockages in his heart. They're gone and I'm looking at this and you know, I'm looking at the two and I'm going, you know, this is impossible. I've never seen anything like this and so the next thing I go is that, wait a minute, you know, tell me about this diet of 50 and so he starts rattling off what he's doing and I'm going, whoa, whoa, whoa, wait a minute. That's my thesis from Yale University of what, you know, an ancient man ate and I said, what the heck? And so I said, well, wait a minute, let me look at those supplements. Now, I was famous for protecting the heart in a bucket of ice water for 48 hours for heart transplant and I was famous because I had this concoction of stuff that I would put down the veins and arteries of the heart to protect it. And I started looking through his supplements and a bunch of the stuff I'm putting down the veins and arteries of the heart, he's swallowing.  So why, so pointed is I was 70 pounds overweight even though I was running a 30 miles a week, going to the gym one hour a day. I operated with migraine headaches. I had pre-diabetes. I had hypertension. I had such bad arthritis in my knees. I wore braces to run. And so I called my parents and said, hey, do you still have my thesis? And they said, yeah, you know, it's in the shrine. And I said, well, send it up to me and I put myself on that program and started swallowing a bunch of supplements that I used to put down the veins and arteries. And I lost 50 pounds my first year and so on and so forth. So I started putting my patients who I operated on on this program so that they would never have to get another operation because quite frankly, the vast majority of people five to seven years later, you're getting new stents or new bypasses. And I said, this gotta be a better way. So after about a year of doing this at Loma Linda and seeing the exact same results that I was seeing on myself, I said, gosh, you know, I've got this all wrong. Instead of operating on my patients and then teaching them how to eat to avoid me in the future, I need to teach them how to eat.  So I literally at the height of my career resigned my position at Loma Linda. And I set up a clinic here in Palm Springs, where I just ask patients, look, every three months, first of all, I want to tell you, I want to take some foods away from you. I want to give you some foods. I want to send you to Costco or Trader Joe's or wasn't an Amazon back then, buy some supplements. I want to do blood work on you every three months that insurance will pay for. And let's see what happens. And of course, I guess the rest is history.   But if we're going to do this, let's do it. So there you go. That's how it all started. Wow. I love that story in so many ways. First of all, I always say curiosity is the hallmark of genius. And you clearly from way back, you never lost that you still haven't. And that I think one of the things that makes great, not only physicians, but great scientists, because as we say, well, what if, or we ask these questions, right? And if we stop learning and stop asking the questions, then we get stagnant and we just do surgery or do whatever we've been told to do forever. So first of all, I love that.  But second, I always, I find interesting, my experience with medicine has also been that we're taught in medical school, oh, patients won't change their diet. So why even try, right? So we're kind of like jaded to come out to like, don't even go there because our patients won't be willing. And that's kind of sad because there's so much there. And there are patients that are willing. And then if we are passionate and we can show the data, obviously it's so powerful. And I feel like there's probably better education now 20 years after I graduated. But it's still, to me, it's always been sad that our medical education didn't talk more about patient and diet. Because again, we weren't, at least for me, it was more like total perintual nutrition. That was it, right? Well, interesting. I was just recently on Mark Hyman's podcast. And his daughter is a third year medical student. And so he mentioned to me, he says, so I, you know, honey, what do you learn in about the microbiome? And she said, what do you mean? And he says, what are they teaching you? She said, absolutely nothing. We have not been taught anything about the microbiome. And he went, holy cow, you know, what? Because there are hundreds, thousands of articles now, which is a transition. Let's talk about, because you and I know diversity is king. And that's such a core, core concept in the gut. Let's talk about that. Tell us a little about why is diversity so critical in our microbiome? And why does it have to do with the rest of the body? So, Abocrates, you know, 2,500 years ago said all disease begins in the gut. And I've now been spending 25 years trying to figure out how he was riding and he was riding. In fact, I don't know if you can see it, but behind me, I love it. I saw the beginning, I didn't see the last word, which is the road to health is paved with good intentions, intestines. And it's so true. The, you know, we've, we've only really recently discovered that there's this tropical rainforest living inside of us with, you know, 100 trillion organisms that, thanks to the human microbiome project, we actually know we're there. We used to think that the human intestine was a hollow tube and we swallowed some stuff and digestive enzymes and juices and acid extracted some stuff and whatever was left over. We pooped out along with a few bacteria and boy, how wrong we were. And really the part of gut check, to me, that's so exciting is that now that we know about these guys and we can individual what, what happens with this incredible community, it's like any ecosystem, the more diverse that ecosystem is, the more one species depends on another species and one species can take over for another species if there is a perturbation in the ecosystem. We now know that the whole same thing happens in our gut. And what's startling, I think to most people and apparently should be to medical students is that most of what we thought and we're trained in medical school is going to happen to us from any disease standpoint is under the control of one way or another of our microbiome and on our gut. And to me, at least the most empowering thing is you choose the disease process and you can change it by changing the gut. It's, I mean, it's really exciting. And no one could have even imagined this except apocrates, apparently. Right. Hey, everybody, I just stopped by to let you know that my new book, Unexpected Finding Resilience Through Functional Medicine, Science and Faith is now available for order wherever you purchase books. In this book, I share my own journey of overcoming life-threatening illness and the tools and tips and tricks and hope and resilience I found along the way. This book includes practical advice for things like cancer and Crohn's disease and other autoimmune conditions, infections like Lyme or Epstein bar and mold and biotoxin related illness. What I really hope is that as you read this book, you find transformational wisdom for health and healing. If you want to get your own copy, stop by readunexpected.com. There you can also collect your free bonuses. So grab your copy today and begin your own transformational journey through functional medicine in finding resilience. Right. Way back if we were to listen. So true. I mean, autoimmune is a classic one because everything on the immune, 80% of our gut or immune system is lining the gut. And so something happens there. I say it's like vagus, right? What happens there except it doesn't stay there. It affects the whole body. You obviously from your cardiovascular surgical point of view have had a big interest in the heart. Tell us about heart-gut connection. Is there any specifics there that? Well, again, it was kind of a big ad that really made me rethink this. Interestingly, one of the great fathers of heart surgery, Michael DeBakey, who I had the pleasure of knowing while he was alive, he always said that cholesterol has nothing to do with heart disease. That cholesterol was an innocent bystander and that how right I think he was. I've used the example in another book. Let's suppose I'm an alien sent down to observe what's happening on earth and to report back to high command. And as I'm looking around earth, we'll choose Los Angeles for an example. I noticed that every time there's a car accident, there's an ambulance. So that I could certainly report back to high command. I'm pretty sure that ambulances are the cause of car accidents because every time there's a car accident, there's an ambulance. So association does not mean causation. And I think DeBakey was saying that cholesterol was the ambulance. And cholesterol is basically, I tell patients, a spackling compound. And it's there to spackle potholes that are caused by inflammation. And that inflammation is actually the cause of the problem. And what's interesting, I think, where did the inflammation come from? Well, the inflammation actually came from leaky gut. And again, it all gets back to apocrates. So I would have thought that this was saw, was put to death, the cholesterol theory or hypothesis at the American Heart Association this year, where low dose culturacine, which a lot of people have heard of as a gout medication, low dose culturacine is an anti inflammatory substance. And low dose culturacine in maximally statin medically treated patients produced a 30% reduction in addition to what they had achieved before, just because it blocked inflammation. And the other thing that well meaning physicians don't know is that statin drugs don't work by lowering your LDL or APO B statin drugs work by blocking toll like receptors, TLRs, which call inflammation into play cytokine. And we didn't know this initially, but I just had a debate with a very well meaning cardiologist who just stood by said, no, no, no, it's, you know, it's lowering apple B. That is the cause of all this goodness. That's a side effect. Come on. So I love that you're sharing that because it really is a lot of these drugs and interesting to a lot of the drugs that we've used, actually have their action on the microbiome when we didn't even know it, right? And then we're seeing that downstream effect. And what you're describing is this endothelial dysfunction, right? The lining of the vessels, leaky gut, leaky brain, leaky blood vessels and all of this stuff then gets that cholesterol spackling that you described as really just sticky inflamed endothelium that draws the cholesterol to try to heal the process. And then of course, the stuff you saw with the cardiovascular disease, but it didn't really start with just an elevated cholesterol. So I love that you're really describing that clearly. So fascinating. And often I think auto immune, whatever we call that, obviously that's the immune system gone or riot attacking itself. But even on the endothelial level, a lot of it is really immune inflammation, auto immune related, and we can actually track that back to the cytokinesine. It's so fascinating. So one thing you mentioned earlier that I wanted to come back to is you were famous for keeping those heart to live for transplants. And you put that solution in there and those nutrients, and then you find out this guy, Tom, was Ed or Tom? Big Ed. Yeah, big Ed was taking these. What are some of the most core nutrients for the heart? I would love to know your list of the top four or five things that you think are critical for the heart. Well, not so much for the heart. But if I was going to have anybody take a few supplements and I've talked about this, vitamin D is number one. One of the fascinating things about vitamin D is that vitamin D is essential for preventing leaky gut. And I go into it and gut check in more detail than I have in the past. But vitamin D, we have at the base of our crips in the microvilli and we can get into anatomy if we want, but let's not bore everybody. We have a bunch of stem cells at the base of all these crips and the crips are at the base of microvilla. And the reason the wall of our gut is a tennis court in surface area is because we basically have a shag carpet in our intestines of these microvilli. And at the base of these are a collection of bacteria and stem cells. And those stem cells repopulate the one layer lining of our gut. But the stem cells are critically sensitive to vitamin D. And if you don't have enough vitamin D, the stem cells basically sit there and twiddle their thumbs and say, I didn't know there was a problem when you want me to do, but vitamin D actually kind of shoves them into action and differentiate. And early on, 80% of my practice is now autoimmune patients who really have not done well with traditional medicine or even, you know, with traditional treatments of autoimmune disease, biologics, which are transplant drugs, folks. And, you know, I'll tell my patients, I say, I didn't do a hard transplant on you when the ding dong are you doing on a transplant drug? And that tends to get their attention. So the interesting thing is all of these people have low vitamin Ds.  We've, I was taught, oh my gosh, once you get above 80 nanograms per milliliter of vitamin D, it's toxic and horrible. And in fact, that's not the case. The University of San Diego, University of California, San Diego, which has a huge vitamin D research unit, thinks the average American should be on 9600 international units of vitamin D, international units of vitamin D3 a day, 10,000 international units. And the recommendation is 600. And I make all of my patients have a vitamin D level above 100. Quest and Cleveland Heart Lab now say 150 is absolutely normal. And I completely agree with that. So vitamin D, the other thing that, again, I guess gets back to heart health. We're one of the few animals that don't manufacture our own vitamin C. And normally vitamin C, a fun fact, is manufactured with five enzymes from glucose, turn glucose into vitamin C. And there are five genes that code for these enzymes. We have all five genes. But the fifth gene is what's called a ghost gene.  Us, new world monkeys and guinea pigs, the fifth gene is turned off. So what? Well, we think we turned it off because we were exposed to large amounts of vitamins C containing foods in the jungle. And so glucose is really good as a fuel for among other things storing fat. So it would be silly if you had plenty of vitamin C to waste glucose in making vitamin C. So we think that's why it happened. Well, vitamin C is essential to repair breaks in collagen and putting on my heart surgeon hat. When blood vessels flex, collagen is the rebar in our blood vessels, and that collagen gets exposed. And if you have vitamin C, you will re-nit that collagen back. My friend, Bill Sardy, who's now passed from COVID a few years ago, showed that you could breed rats with the same genetic defect as humans where they do not manufacture vitamin C, and they will live half as long as a normal rat. If you put vitamin C in their water so that they're drinking their vitamin C, they will live a normal rat's life as long as vitamin C is in their water. And he did some fun calculations that would predict that if we had a continuous source of vitamin C, we would live about 252 years on average. Wow. Wow. So time-release vitamin C, I think, is another really neglected, essential nutrient. And luckily, time-release vitamin C is cheap. It's easy to afford. And I have all my patients take 1,000 milligrams of time-release vitamin C once or twice a day. If that's really inconvenient, get yourself some chewable vitamin C tablets and just chew it four times a day. So that's two things that are really essential. Well, I love it because these are not expensive, and they're so accessible for every American, every human being. It's not a difficult thing. And it reminds me back my history. I had breast cancer at 25 Crohn's and celiac at 26. And guess what? I had a very severe genetic impairment of EDR, which is the vitamin D receptor. And I look back as I hear you talk. I know multiple things that contributed to that, but I am sure one of them was my severe deficiency of vitamin D going into that. And then, of course, chemotherapy caused the leaky gut, which caused my predisposition towards Crohn's to become activated. Now I'm free 20 years from Crohn's. I don't have it anymore. But I'm really, as you talk, I'm very much aware of the fact of how much vitamin D had an effect on my own health because I was probably severely deficient, not knowing I had that VDR gene. Yeah. I mean, in my practice, in Southern California, 80% of people who walk through the door are vitamin D deficient. And it's like everybody goes, that's impossible. It's funny all the time. And the problem is, of course, we've been convinced that we got to cover up with sunscreen and we got to protect ourselves with long clothing. And the exact opposite is true.  In the coldest sun. So good. And like I said, I love the practicality of this DNC, so simple for people to get. You talk in your book, which we're going to talk at the end, where people can get your new book gut check, but about cultures and other cultures that sometimes they do a better job of Americans at getting the micro nutrients and diversity. What are some of the things that you've seen in other cultures or continents that are really key to maintaining how healthy gut that maybe we don't do well or that we're just starting to do? Well, one of the things that is fascinating to me, first of all, it sounds trite, but most of these cultures eat food whole. And everybody says you're supposed to eat a whole food diet, but we forget that the word should be actually we should eat foods whole. And these people eat a lot of tubers, quite frankly. The other thing that's striking is that almost all of these cultures eat fermented foods. And things as simple as yogurts, things as simple as cheeses. We forget that cheeses are fermented foods. And I spent a whole chapter debunking the blue zones. They I think should be called white zones. And I'm the only nutritionist who spent most of my career living in the only blue zone in the United States. So you can know a little bit about what I talked about. I have a funny story in the book when I was recruited to Loma Linda, and I'm not an adventist, but I was recruited and I met with the dietitians. And the diet was 50% fat, was mostly cheeses and yogurts and eggs.   And they said, look, Sonny, you know, we're some of the, yes, Sonny, we're some of the longest living people in the world.  And the other thing that struck me years later is everybody says, wow, you know, they all this plant protein and they eat a lot of nuts. We have nut everything at Loma Linda. But their main plant protein is texturized vegetable protein, TVP. What's fascinating is it's defatted soy that is extruded under high temperature and high pressure. So that the really nasty compounds in soy, lectins, are destroyed. And nobody wants to point out that, boy, the adventists look a lot smarter than you guys think. They're not sitting around eating tofu. They're actually decontaminating their lectin-rich food by pressure cooking. I didn't know that. That makes so much sense. Speaking of food, what is the optimal dietary or diet for the gut? What are some of the principles that you would recommend? Wow. Well, one of the things that I think made a real impression on me is the Sonnenberg team, the husband and wife team from Stanford. Everybody knows that prebiotic fiber is really important for our gut microbiome. It's what the gut microbiome eats. And that prebiotic fiber should be actually soluble fiber, not insoluble fiber, number one. Insoluble fiber. Things like, for instance, one of the best sources is Jerusalem artichokes, sometimes sun chokes, artichoke hearts, the cruciferous vegetables, which are great in themselves, but the vegetables like chicory-based. One of the easiest things to find on almost all grocery stores now is radicchio, that what people call Italian red lettuce. I'm shocked when I'm, excuse me, in Italy or France that every salad I think I have ever been given has chicory in it, whether it's radicchio, whether it's Belgian endive, whether it's frisee, whether it's chicory, every salad. And you start going, what the heck? Why are these guys eating this stuff? Well, it's a great source of prebiotic fiber. But getting back to the Sonnebergs, they took volunteers and they gave them a ton of prebiotic fiber, primarily in the form of inulin, which is in chicory. And they looked at their gut microbiome diversity and they looked at their inflammatory markers and they didn't see any change. You go, well, that's weird. So they took an additional group of volunteers, gave them the same prebiotic fiber, but this time they gave them fermented foods, primarily in the form of key fears, vinegars, yogurts. And it was only with the addition of these fermented foods that they then saw with the prebiotic fiber, the gut diversity improve and the inflammatory markers go down. And so I almost hate the expression, but it really does take a village to get what we need. So most people think of fermented foods as a great source of probiotics, friendly bacteria. They're not. They are a great source of post biotics, which are the products of bacterial fermentation. And there also, as I talk about in the chapter, dead men tell no tales, but dead bacteria do. And it turns out that dead bacteria are this amazing communication system to our living bacteria about what's there and what they should do. And it's just shocking to see what happens. So yeah, eat fermented foods. All of these cultures eat fermented foods. It's easy to do. I have my wife and I have probably 10 different vinegars that we alternate. Get yourself some goat yogurt or sheep yogurt, not the flavored or coconut yogurt. And have yourself some traditional fermented cheeses, believe it or not. Parmesan cheese, pecorino is great for you. Exactly. This is so great. And I love that you mentioned a couple of things as post biotics. And my work on a little bit of cardiovascular was that short chain fatty acids, butyrate production, those post biotics that are so core to anti-inflammatory. And now we can actually measure those in patient's stool or in some of the testing. But I see frequently that butyrate acid is very, very low. And that's one of the most powerful anti-inflammatories. And it comes from butter and cheese and also post biotics. The other thing you mentioned I thought was so profound and important for patients and people to hear today is that dead bacteria can talk to us. Because we thought for years, in fact, as I've been teaching you about diversity and acromancia, which is one of the keystone strains, of course, that tells if we have diversity or not. So if you lack acromancia totally, you're going to have less mucosal barrier, less diversity in general. And for years, you couldn't culture this in a row because it's very hard to culture and give. Now there is a company out there that has acromancia. It's dead. It is completely pasteurized. It's a dead probiotic, but their evidence is showing that that dead probiotic, as you mentioned, has a powerful anti-inflammatory effect on the body even though it's dead. So all this controversy years ago of do we take our probiotics with food without food, does the H2O kill them? Maybe it doesn't matter, right? Because the dead probiotic is still going to have that signal to the immune system. Yeah. I use the example. We have some rescue dogs, and a few of them are male dogs. And of course, they like to mark things, but more importantly, they like to sniff what other people's dog's pee has. And you go, what the heck?  What's so interesting? Well, that urine contains lots of information that they get that we have no idea what they're smelling. And what we now realize is that our living bacteria can read the code on these dead bacterial cell wall, and they literally get information from it. And just because we can't read that doesn't mean that somebody, the bacteria, can't. Wow. Amazing. Now you mentioned about 80% of your practice now is autoimmune, which is just becoming an epidemic. Women four times the amount of men. What would you say for autoimmune disease? Is there a few pearls that you would could give us here that you give to your patients with autoimmunity related to the gut? Well, the good news is that, and I've published this data, within a year, 90 plus percent of people with autoimmune disease are in remission. They're off of their meds, which is pretty doggone good. The first thing to realize is that everyone with autoimmune disease has leaky gut. Period. Get over it. 100% of my patients with autoimmune disease, whether or not they're eating wheat or gluten, have antibodies to the various components of wheat. Wheat, germa, gluten, and all the different forms of gluten, non-gluten proteins, 100%. So, and I have people who've been gluten-free for 10 years who have massive antibodies still, IgG antibodies to gluten. The good news is, excuse me, this goes away. It completely resolves. And does that mean you can have it again? Maybe if you go to Europe where they don't have glyphosate? Hearing the United States, I could tell you stories that we don't have time for, but glyphosate is just a disaster for us. It's one of the big mischief makers in autoimmune disease, and it's everywhere in our food supply. But so we get people to give up grains. The only safe grains in my practice are sorghum and millet. They don't have a haul. They don't have lectins. We ask them to pressure cook their beans and their lentils. We get to, we have them throw away their peanuts and cashews. Sorry. And we ask them to peel and de-seed tomatoes and peppers because they contain lectins. And we've had a great run, and that's how people end up in my clinic. But it's all in the book to, if you've got an autoimmune disease, it is a fixable problem. I promise. And does it take some work? Sure. But the good news is we'll get you back a lot of the foods that you want. The other thing I think is striking, great number of my autoimmune patients react to all forms of dairy and both egg yolk and egg whites. The other thing that surprises a lot of people is that almonds, even almond flour, even blanched almonds are problematic for a number of my patients without autoimmune disease. Gosh, I agree on all fronts. And it's stuff that is so important, but not many people are talking about it to the level that you are. So thank you. Dr. Gundry, the last question for you is, personally, you've done a lot of stuff in transformation, and you talked about your journey after your patient. You saw this transformation. What do you feel like is your most important key to longevity and health for you personally? Oh, gosh, I think you hit on it early on is one of the things that's interesting in traveling around the world, looking at these long-lived populations is these super old people have a mission. They firmly believe that they are there to help their community, to help people understand what got them there. And I guess it's this discovery. We joke. I've written a lot of books, and my editor always wants an outline before I start writing, and I refuse to give her an outline. And so we can't write a book without an outline. And I said, well, if I give you an outline, but guess what? Everything's going to change by the end of the book. Just write something down and humor me, because I'm not going to prove you doing this without an outline. And of course, every time I write a book, I go down rabbit holes of discovery, and I don't write a new book unless I've got something important to tell people. And I still see patients six days a week in my mid-70s. And so the reason I do this is you get to see, I get to see miracles nearly every day. And so that's I love that so much. I'm just in the midst of reading a book by Gladys McCary, which was, I think she lived to be 106. She was a medical doctor. She talks about the life well lived. And the first part of her book is the juice. It's the thing you're talking about. And I'm talking about what gets us up in the morning, what gives us passion and purpose and meaning in life, and how do we use that juice to transform people's lives and inspire. And clearly you've got the juice. So I love that. I loved how she said it, because at 106, she's like, you got to have the juice. Yeah, that's very true. That's very true. Well, thank you for your amazing work in the world. Gut Check is coming out January 6th. So whether you hear this right before or right after that, you can get your own. January 9th. Tuesday. January 9th. Yeah, always Tuesdays. Harper, it's one of the Harper subsidiaries. And January 9th, you can get it. Where can people find you? Where can they get the book? Well, they can get the book wherever books are sold. Please go to your local bookseller. They really suffer during COVID, as we all know, and they need our help. But Amazon, Barnes & Noble, Target, the usual spots. DrGundry.com. GundryMD.com is my supplement of food company. The Dr. Gundry podcast, wherever you get your podcasts, and my YouTube channels. And if I don't pop up on whatever you're viewing every morning on your cell phone, I've done something wrong, I guess. Oh, I love it. I love it. We'll go follow Dr. Gundry, find his resources, check out his website, and please get the book. This is going to be a game changer for all of you that are suffering from auto immunity, or really any chronic medical condition. Dr. Gundry, thank you for taking your juice and making such a difference in the world.