This study aimed to identify potential new antimalianogenesis agents for treating hyperpigmentation disorders. The authors used computer simulations to evaluate the binding affinity of four proteins with 94 ligands, then selected the top 13 ligands for further analysis. They also conducted multiple ligand simultaneous docking to determine which ligands would be best suited for further testing. Finally, they evaluated the pharmacokinetics of eight compounds and found that Novobiosyn sodium was the most suitable candidate for further investigation.


Is Raven's offensive line strong enough to allow Lamar Jackson and the wide receivers to make place? Are Ravens ahead of the curve with the type of offense that they've been saying they're gonna put on the field? Should running back Gus Edwards still be our starter even with the Ravens signing Mark Ingram? These and many many more questions on this episode of NFL Questions from Subscribers. YouTube team keeping clean what's going on this Engraven here with another video and another episode of NFL Questions from Subscribers. This is a series where you can ask me any NFL question you want to based off of any NFL team and we answered in a video just like this. If you want to be part of NFL Questions from Subscribers just send me a DM on Instagram, Twitter, Snapchat, Facebook or you can send me an email at teamkeepingclean at gmail.com or you can send something to the PO Box. The address and instructions for that are in the description. Let's not wait, let's not beat around the bush, let's dive straight into this episode of NFL Questions from Subscribers. First question came from a boy Bobby. He said yo what's going on my dude just wanted to start by saying I love what you do. I appreciate that man thank you for watching the videos man. He said been a viewer since the ending of the car videos.  So appreciate it man. He said I watch everything involving the NFL your opinion is as raw as it comes. Oof I don't know if that's a good or bad thing but nah I thank you for that man. I hope you and your family stay up and one day I get to introduce my family to Team Keep It Clean. Appreciate you man big time man. He said this question is hearing RG3 injured his thumb do you feel that gives Trace McSawley more reps since he would be number two and how many wide receivers and running backs do you think we're going to run with? So yeah that definitely pushes Trace McSawley up on the depth chart right away. Especially with the team having signed Josh, Joe Callahan I think Joe Callahan. He's not going to make the team. He's just there as a camp on there and that's a nice little job man.  But anyway well I guess this is a temp job so same thing. But I was going to say what kind of job is it where you know how much you're going to get paid and you know how long you're going to work for. You know when your work will be coming to an end. So he goes into this situation knowing that he's going to be paid for maybe about a month because that's how long the preseason will be. Yeah and because he's not going to make the active roster he's not going to make the team. He knows that we know that everybody knows that but he knows how much he's going to get paid for how long he's going to get paid that amount. Then he's going to be done and that's it. So with Trace McSawley that has elevated him since RG3 is out. Joe Callahan is in. That elevates Trace McSawley up. So this is good for him. This is good for him to get more reps, get more time, get to be able to run with the twos now instead of the threes. So this can only help him and this can only help the team because it can make him better and it can elevate his game. So he can just be a better player and he can get more reps and get more time on the field and whatnot and just get more acclimated to becoming an NFL quarterback. So it's a real good thing for Trace McSawley. And as far as your other question, how many wide receivers and running backs do you think we're going to run with? For the running backs it's so tricky. Wide receivers kind of too but running backs I think is even trickier because I think the bigger question is if they're going to keep or cut Kenneth Dixon. And it's like, ooh, that is a tough one. Because when he was healthy last year, he came on, he came on strong for us. He ran really good, he ran really strong, he was a powerful runner. But now you just drafted, you got Mark Ingram and Gus Edwards and Gus Edwards has been looking really good. But then you got a Justice Hill too who you drafted. So those three guys are locked to make the roster but now what? Now are you going to keep four running backs or are you just going to keep three that are your locks? That is so tough because every position is that valuable. Of course the Ravens, they will be implementing a running game. Now while I think of course they're going to be having a strong running game and that's going to be a big part of their offense, they're definitely going to have a passing game too which I think a lot of people are sleeping on. So right now I am, I'm going to say six wide receivers. I'm going to say six wide receivers. I'm going to say four running backs right now. It's just hard for me to see this team cutting Kenneth Dixon. I just, Eric D'Costa I think he's going to be a little more no-nonsense than Ozzie Newsom was. It's really hard for me to see this team cutting KD. It's really hard for me to see them doing that. And of course it's going to come down to the numbers because it's a numbers game. You can only keep 53. And of course they're going to do their maneuvering around. Hopefully they won't have to maneuver anybody around because of injury because hopefully everybody will be nice and healthy. But it's a numbers game.  But that one, that is like, I think that's the toughest decision that they have on a roster is who they're going to keep it running back and who they're going to keep it at punter. Next question came from my boy James Holman. He said engraving. He said hey engraving and all team keep it clean subscribers. He said reports out of Green Bay training camp is that Zadaria Smith is looking like Julius Peppers. If true, did the Ravens make a mistake letting him go in free agency? And how did hardball miss on somebody who compares to Julius Peppers? And what do you think of Buster Scrine? Is he any good? I keep hearing that he's absolutely trashed from Browns fans. I mean from Jets fans. And join the Vizz keep them coming. So appreciate that James. Thank you man. First question though is about Zadaria Smith. He said if it's true did the Ravens make a mistake letting him go in free agency? That is actually the one free agent I had really wanted us to keep. I wasn't like kicking and scratching and clawing or anything like that. Oh man, they really had to keep him serious. I was like okay, if they let him go, they let him go. But he was a guy that a lot of people were like nah, we shouldn't keep him. We don't need to keep him. But I liked Zadaria Smith. I liked him. I understand why they let him go. Because when it came down to the numbers and they knew Zadaria was getting ready to cash out. He knew he was getting ready to cash out.  So was Zadaria Smith. I mean, yeah, I did hear about reports of him looking really good. Again, his training camp though, so I can't really put too much stock in that. Because like I said it is training camp. So if he's doing it in the games, okay, let's see then. But yeah, I think he'll do well then. I think he'll do well there. And he won't just be a product of the opposite side of Terrell Suggs. If he does do well in Green Bay though, he would be the first. He would be the first like Ravens defender. Well first in a very long time. Because the dailiest time instead, he did okay. He did pretty good in New England. But he would be one of the first recent Ravens defenders to actually leave Baltimore and actually do well. Because once most like 99% of Ravens defenders leave Baltimore, they don't do anything good. They're not special players anymore. They just kind of fade away. They get paid, but then they fade away. So hopefully for the Zadaria Smith and the Packers sake, that doesn't happen. But was it a mistake for the Ravens to let Zadaria Smith go? I can't call it a mistake because it's not like, oh, they didn't feel like he was talented. And that's the reason they let him go. Or it's not like they missed on him. Or they didn't maximize his potential when he was with the team because they did that. I think it was just more so the money. It was the money factor. They knew they didn't want to pay him all the money that he was going to make. So they just didn't resign. So I can't really call it a mistake. But I do hope he does really well in Green Bay. Because I do like seeing some old Ravens. I like seeing them go their separate ways and then still do well. So I'm hoping the best for Joe Flecoe in Denver. Sucks about Buck Allen. The Saints put him on Endure Reserve. Terrell Suggs, I do want to see him do well, except in week two. Max Williams as well, except in week two since they both on the Cardinals. Anyway, I ain't got to go down the whole list. But oh yeah, CJ Mosey too. CJ Mosey, we'll be watching him this season. I hope he does this thing too. But yeah, I can't call it a mistake. Now Busta Scrine, Busta Scream, whatever his name is. I know he was with the Browns a long time ago too, I believe. And then they let him go. They didn't resign him and then he signed with the Jets. I had actually wanted us to sign him. But I think back then when I wanted us to sign him, I think I'd been playing so much Madden and he was a fast quarterback in Madden. So I was thinking in Madden terms. And I was just thinking speed, speed, speed, speed, speed. But I didn't even know he was still in NFL. I really didn't. I haven't heard his name in so long. But yeah, when he was with the Browns, he wasn't really good. And I guess nothing really changed when he went to the Jets. So yeah, oh, is he a packer now? What's going on with that? Because I'm not sure where he is. I don't know what his status is. I don't know where he is now. But yeah, anytime I heard a Busta Scrine, it hasn't been anything good. So take that as you may. Next question came from a boy. Wyd Johnny. And shout out to him. I got to meet him at the Ravens Open Practice. Real cool dude. But anyway, he's goofy too. He was laughing a lot. So shout out to Johnny. Anyway, he said, what's your opinion on the NFL's top 100 list disrespecting the Ravens this year? I don't think it's a big deal. The top 100 list doesn't mean anything. It doesn't hold any weight in anything. It's not all pro. It's not even a pro bowl. It's like nothing. Like nothing comes from that except just to it's the NFL. Top 100 list just serves as another way for people to pass time until the football season actually gets here. The list means absolutely nothing. The list is not special at all. It's a cool list to just watch, to watch highlights and stuff. See what different players say about different players and whatnot. But I don't take it as any disrespect to the Ravens. I just don't think it's anything serious at all. Next question came from a guy. I got the juice too. He said, my thing is with Lamar getting the ball out to our receivers for them to make plays, could or would the line hold up long enough for Lamar Jackson to make those plays? So the offensive line, that's a good question because without the offensive line, the team is nothing. The offense is nothing because the running backs, they won't be able to break free. The quarterback won't have any time to throw the ball.  It would just be bad on so many different levels. So it all depends on how they construct this offensive line. They have to do like Eric DeCosta said, and build a bully. And that building a bully starts with the offensive line. You got your two outside bullies even though they said Orlando Brown hasn't been having the best camp. But again, I'm not worried about that at all. Maybe he's just one of those guys that just wait to show it in the real games. So you got Orlando Brown and Ronnie Stanley on the outside. Yonda on the inside. You got Scurra. But that left guard position, I think that's probably the biggest story of this offensive line. Who is going to be there? Because all the other positions are pretty much set. I don't see them giving both men a starting center job. Something crazy happened, but I just don't see it. But left guard is the position that we really need to solidify this offensive line on or in or with. And who is that going to be? Is it going to be somebody whose name could be as strong as they are with Ben Powis? We'll see. Or they're going to go with a veteran or somebody who's been around that being James Hurst. Or even Alex Lewis. I think right now the one up is the, or the leg up on the competition will go to James Hurst. But hopefully for Ben Powis sake, hopefully he can be like Orlando Brown last year. But the Ravens will make a better decision than they did with Orlando Brown. Because Orlando Brown showed in preseason and stuff that, hey, he can hold it down. But the Ravens still opted to go for that veteran presence at the right tackle position. And it wasn't until injuries happened that they put Orlando Brown Jr. there. But they did realize that, hey, wait a minute. Once James Hurst got healthy again, he never saw that right tackle spot again. So they just got a mixing match with the offensive line already just with that left guard position. Because all the other spots are pretty much set. So they got a mixing match with those positions and see who really provides the strongest left guard that can really help hold this offensive line together. Next question came from a boy underscore one Rocco. He said, do you think Gus Edwards should still be our starter? I think he earned that last year and I hope he starts this year. Yeah, he did. He did. He really did. I think he should still be the starter too. In training camp, he's looked really good in preseason. I'm sure that will continue because since he did lose a lot of weight, he has more of a burst. He has more of a burst. Now, when I saw him, it didn't look like he was lacking too much in the strength area. But let's see again what he does against opponents. But I think he should still be the starter. Now, of course, it's going to be a lot of Mark Ingram too.  No, they paid him all that money to play. So even though for a deal for running back these days, that's pretty cheap. $5 million a year. You see charges, even though he's trying to get traded now. Melvin Gordon, they said they offered him $10 million a year. And you see the money that Todd Gurley, Devante Freeman, got these huge contracts. So Mark Ingram is a steal money-wise for the Ravens. But I do believe that Gus Edwards should still be the starter. Now, him being a starter, he's definitely still going to share plenty of carries with the other running backs, whoever those may be. But yeah, he should still be the number one guy. Next question came from a boy, Connor Lavery, 99. He said, do you feel like the Ravens are one of the few teams ahead of the curve of setting a new trend of Smash Mouth running offenses? I can also see the Patriots loading up on quality running backs. And if Belichick buys into this power-running game and other head coaches, then other head coaches will follow. Appreciate your videos and much love from Ireland. Whoa, way from Ireland. Appreciate that, man. Thank you. This is an international question from a subscriber. So thank you for that, man. But with the sort of Smash Mouth football, I think that's more old-school football, if anything. I don't even think it's the Ravens changing anything or setting a new trend. That's just old-school football. Just run, run, run. And especially old-school Ravens football. Strong running game. You make some plays in the passing game, too. But your foundation is built off of strong running game and strong defense. So a strong running game and an efficient and strong running game. So efficient. You convert in first downs. You score some points and you're controlling the clock. And then, of course, the defense. The defense is holding it down. And they are keeping the opponents out of the end zone and holding up their end of the bug. So I think it's not necessarily new. It's not a new trend. It's just them going back to their old ways. But I don't think that's how the offense is going to be. I think they're definitely going to have the running game involved. But the passing game, I think right now, is super underrated. You can also see the Patriots loading up on quality running backs as Belichick buys into this power running game. And other head coaches follow. Now, with Belichick, they usually do that anyway. They usually load up on quality running backs because they do a lot of share the wealth in New England. That is one thing that every single year you can guarantee that they share the wealth. They will go with the hot hand during the game. But that hot hand may not always be the same hot hand every single week. They are going to provide a lot of different opportunities to different guys on the team.  With them, there's usually not the standout. Well, Sonya Michelle did this thing last year, but they have been doing running back by committee and just really wide receiver by committee. They've been doing a lot of stuff by committee over in New England for a long time. And of course it's been working because they've been winning. Even though some people could say they've been winning for other reasons too. But they do a lot of the short passing game and a lot of stuff set up for yards after the catch. And a lot of that can come from check downs to the running backs. That's why with their running backs, they get a lot of quality running backs like you did say. And they need to make sure they have running backs that can catch. But this was a really, really good question and I appreciate it. So shout out to Ireland, man. Next question came from a boy originally saying, and this was before Hollywood returned. But he said he hopes that Hollywood will be 100% healthy and 100% ready to play. Well, this is actually right when he returned, excuse me. But he asked, do you think that Miles and Hollywood will work on the same group or will he be on the second group? So yeah, when he first started, he's been with the second team. He hasn't even ran the regular practice yet. He's just been doing drills. And this is as of today's August 2nd. Now by the time y'all see this video, that could have changed. But we'll see. But he had just been doing drills for the most part. So he'll eventually, I'm sure he'll eventually get up there with the starting team that give him some looks and different looks and stuff with the unit just to see how he fits in. But for now, yeah, he has been with just doing drills. Not even running with backups anything but strictly doing drills. So once he gets on the field, I'm sure he'll be working with maybe the third, the second unit. And then they'll want to keep on pushing him so he can work his way up.


Rydyn ymdae yw'r wiwn. Rydyn頰 wrth masculynaeth eisiaid ac fawr i masculinaeth eisiaid, masculinaeth eisiaid... Mae yna ymddangos, mae mae yna eisiaid, ac mae'r ideaf buschus masculinaeth eisiaid. felly mae'n fwy o ddod wrth a Constiwyr ac mae'n gwasgliw amdannu ddefnyddio'r hollau fel wrth unig yn dywedbeth. Mae fe wnaeth i ddechrau cefnodol o gael how psychologists across America must unify in training young men be a man is bad for their mental health, that masculine traits are bad for your mental health. We live in very very strange times folks, anybody watching this on YouTube that thinks this is just a roomful of men concerned with men issues, what I would say is that the defence of masculinity is the defence of humanity itself. The end goal is not to put women in charge. Women are tricked. Women are tricked who think that. Feminism, the ambition, the agenda of feminism, the cancer on culture that is feminism, is to trick women into thinking that they will get their moment in the sun, that they will be in charge. But that's not true. Women will not be in charge. Men will not be in charge. We will all be enslaved and subjugated. There will be no men, there will be no women. There will be what Jack Donovan has referred to as androgynus, genderless, worm people who consume. We are being trained by an extremely evil agenda to be the best voters and the best consumers we can be, and there is no other concern.  Never did. It was never about social justice. It's only about subjugation, enslavement and entrainment. Attacking men was necessary. Why? I said, yang. Men are yang. Men were the boundary. Men were the boundary. Men were the wall. Men were the last line of defence. And that's gone because there was a little trick that was used, developed by the communists.  It is verifiable, objectively, it's called demoralisation. Train the women into an ideology of conformity, vanity and victimhood that causes them to hate men and to show men contempt. And what happens when men lose their women? They become depressed. Are we not depressed? They become listless. Life has no meaning. Life has no passion. Life has no juice. Men clearly live for women. Hang on a second though, I thought men hated women. I thought men lived just to subjugate women and enslave them.  Because women don't want us anymore.  True or false? I'm afraid it's true. So here we are now, and what would I say to a young man in this society, in this culture right now? And he said to me, how do I be a man and how do I be masculine? I would say you need to recognise all of this. You have to absorb all of this. You were raised, you were born unfortunately in a very, very strange time where the essence of who you are, you are not allowed to be that.   That's a problem. I'm sweating now. I told you the effigynt would kick in. So in this version of events, in this timeline, in this reality that we're up to now, masculinity is a decision to be as opposed to not being. This that we face is not feminism.  This is a death cult. This is a death cult. The purpose of this cult, as I say, and as Jack has said, is to turn as all men, women, children, trans, everybody, nobody is safe from this, into genderless, identityless, worm people who will literally be put into pods, literally. I swear you will see this in the next five years. Pods. Pods are coming. There won't be called pods. There will be virtual reality machines or whatever, but we will be facing heavy pressure to get into pods because it's pleasurable. So the pleasure button is going to get pushed, as it always is, with these people and for the good of other people.  Consumer capitalism as it is today is evil. I'm a capitalist, but we need to recognise the difference between free market capitalism and consumerism. It behooves consumer capitalism to provoke and invoke evil in people. The seven deadly sense. Lust, sloth, greed, envy, rage, because people are in that state, they buy and they submit and they do as they're told. Recognise that. Yang is the choice to be. There is going to be conflict in this choice. If you think about the very raw level of reality, the structure of human genitalia, that which is the yang is an audacious thing, that's a daring thing, but it is standing out and it is visible and it is punishable therefore. Safer to be horizontal, safer to be flat. We're talking ones and zeros. We're talking being and not being. I'm not trying to say yang is good and yang is bad, they need each other. They absolutely need each other. But this is the choice between I would claim a life, one of passion, one of red bloodedness, one of individuality, one of being able to be who you are, whatever that is, I'm all for it. I'm all for people spontaneously being whoever and whatever they want to be. The forces that we face are not. They demand submission and as I say it's a death cult. I'm reminded frequently of...


Hey guys! Happy Easter! This is my get ready with me for Easter vlog. I was gonna do a TikTok and then I was like, no, because I want another video to post. Like, I like the two videos a week thing. I was kind of when my head started doing. So this is just gonna be like a dedicated like little get ready with me. So the first thing I do is get on my outfit. And I'm gonna talk about when I'm getting ready, like why I do the order I do. I have an idea. Well, I have two ideas. I love how they're both green. I'm thinking I'm gonna go with this one because I haven't worn it in a hot minute. This is from Luca and Gray. It was asked from the store that is no longer. And then I have this one. This is really cute too. It's giving like Venetian. Maybe that's the wrong term. But I'm thinking I'm just gonna go with this one and wear tennis shoes with it. For getting ready purposes. I just have my slippers on. Okay, so this is the dress. I think it's so cute. I'm gonna warn this. I think it's been a year since I've worn this dress. I'm glad I picked this one because I'm a little bloated right now because it's that time of the month. So I think this is a good option. Okay, so I'm just gonna like brush out my hair and then put heat protected on it. Because I like doing this before my hair actually gets curled. Because the longer it has to like sit on the hair, the more my hair can like air out and everything will not air out. But like the heat protect it can like dry. So that's why I kind of just like to do this as the first step. So I'm just gonna squeeze this in. Luckily this dress is kind of comfortable. Because at first I really didn't want to wear anything like kind of fancy.  Easter only happens once a year. So might as well. Why not? See this is when if I was doing a TikTok I'd be like, get ready with me for Easter. But we've already covered what we're doing. So I'm not doing anything crazy for this look makeup look. But always gonna start out with the brows first. I tried to like pluck my eyebrows just because I just thought that they could use a little bit of cleaning up. I try to do that every so often. But I'm definitely not a pro at like anything brow or brow related. I'm barely getting by honestly. You know the funniest thing too is like I love watching get ready with me and listening to people. But like when I go to do them I'm like what do I talk about? Like on the most random occasions I'm like oh I'd love to talk about this. And I just like I get the ideas at the most random times and then I forget the idea. I used to make notes but I kind of stopped doing that. Come on man sometimes I just like pray that they turn out okay. I don't want them to be like too crazy. I did want to take a cute Easter picture too today. I don't know if we're going to actually get that or not. But you know having a good goal will be good. I'm thinking about this that one time I was talking to you guys and I was like oh I hope I get a good profile picture. Yeah that didn't really happen. But you know it was fun to take the pictures and stuff. So it wasn't always because I did have fun but none of them really worked out. So I saw this thing on TikTok and it was basically like the order of getting ready. So this one girl was like oh I do hair. No I think she said I do makeup in my robe. And then I do my hair and then I put on my outfit. And then other people were like oh no I gotta do hair first. Because I don't know the reason but like I was looking at the comments and it was like telling me the order of how you do things. So I do everything backwards I feel like. Well maybe not everything but I do not know why people wait to put on their outfit. And yes I know that you have a chance of getting makeup on this. Like I completely understand it and watch. I'm probably gonna get makeup on it now that like I'm talking about it. But in a normal world knock on wood I do not get like drops of makeup on my outfit. The reason why I always do my outfit for everything else is because I am guaranteed to get makeup on it if I have makeup on and have to put anything over my head. I'm gonna get makeup on it. That's why I hate trying things on in stores when I have makeup on.  And I'm not like doing it on purpose. But I don't know how people unless you really stretch out the neck of something which I don't want to do because you don't want it to be like so stretched out that you know you've harmed the item. I don't know it's just complicated and I cannot stand even putting anything on with makeup on. Or for that matter taking anything off with makeup on. Like I'm guaranteed to get makeup on it from my face. Because I don't know how to put on a shirt. Without getting makeup on it. So if you guys know how to put on a shirt without getting a makeup thing like on the neck. Let me know because all these girls were like yeah that's the way I do it too. I'm like I do it completely opposite. I put on the outfit and then do my makeup. And then I save the last for my hair. Because well since I don't do a whole lot of makeup like in the grand scheme things I don't. I mainly do makeup to like just even out my skin. I'm no makeup beauty guru. I used to hate makeup as you guys know. And yeah but I started liking it a bit better because I found like makeup that I like. And it's not too uncomfortable for me so I don't mind it as much. But also too I'm not like willing to spend the money.  So I don't do a lot of makeup so that's why I do my makeup second. Because I like to spend a lot of time on my hair. Because I love doing hair like I love curling my hair. Like if it comes to one if it comes down to like picking one or the other I will do my hair. So if I really don't feel like doing makeup I'm like ask or like I'll just do my hair. To make myself feel put together and nice and everything. When it boils down to it my hair comes like first.  So I just do a quick little makeup look and call it good.  That's why I save my hair to the last. And half of me loves my hair straight. Like sometimes I do like the straight hair. But then I just feel like so like more girly and stuff with curly hair. So that's why typically when I do get ready I do curls. And I got the new curling iron for Christmas. It was funny one of these comments was like oh that's just like a normal curling iron. Well for the longest time I used a curling wand. Which I still have and they're next to each other. I really wanted a curling iron because of this girl. I liked the way she did her curls. When I'm in a really big hurry though I just use the curling wand. Because like I know how to work that one really fast. But if I have a little bit more time and I really want more Dyson air wrap looking curls. I will just use the curling iron with the clamp. So I'm going to definitely do the curling iron with the clamp today. I like the way those curls look. I always go back to touch up my eyebrows after I do like my face makeup just because. I just like to get like the final like kind of shaping done. Because I find that the face makeup kind of like blends them. I don't know it's just something weird I do. And then I put on the eyebrow gel. I just brush them up like this. I'm not going to do bronzer today because I don't feel like it. I feel like I say that in all my get ready with me's or TikToks for that matter. Because I do more like little get ready with me's on TikTok. I will say they're a lot easier to edit on TikTok.  So because I get paid on YouTube I don't mind just spending a little bit more time to edit them. And guys honestly I'm kind of surprised that I still get paid from YouTube. Because of like all my my lack of uploads have been pretty bad. That's why I've been trying to do at least two videos a week. It doesn't sound like a lot but when you just don't feel like doing anything it's a lot. But I'm happy to say I still get paid. And then I got paid guys for my commission links. So like when I link things down below obviously they're commission based kind of.  I get like a chunk of change. And literally when I say change I mean change it's not like that much. But I got paid from like to know it and I'm like oh my gosh that's so cool. Because sometimes some months I don't get that commission because I don't meet the threshold. And then sometimes I do. But like somehow I'm always meeting into YouTube thresholds. So I can't complain and I'm really thankful and happy because to still be able to say like I can make a little bit of income off of YouTube is like still a dream to me. I love it. So thank you guys for always watching and clicking my links if you ever click my links. Oh another thing I wanted to talk about is this camera I've been really wanting. Like I feel like a couple more YouTubers are using this camera. And it's the Sony ZV1 Mark II. And I really really want it. My Canon DSLR has been up on eBay for a hot minute now. And I just really wanted to sell because I'm gonna use that money to buy my new camera. So I'm like crossing my fingers. I typically like to put the items that I want to sell up near Christmas or like holidays. Because I know that people are looking for that stuff. But no one's really like shown any interest that big DSLR. And I know it's like old. It's an older version. So I know it probably won't get any traction but I'm like low key hoping that that one will like I don't know do well and get sold so I can buy the new camera because so the new camera I really want because it has this sort of lens. Like it's a wide angle lens like this camera. This is the Canon EOS M50. It's a mirrorless camera. It's like a medium size. So like it's not as big as a DSLR but it still has interchangeable lenses because this is an 11 to 22 millimeter lens. That's why it's like wide angle. So yeah like I really want this camera because it has this lens this whole thing. But it's almost the size of the Canon G7X. So I would still get the same look but it'd be on the G7X like size. It'd be around that size. Oh I should plug in my curling iron. Long story short it gives the same image similar to this one. But the camera is just a lot smaller.  And I just really like that because I've been using if you guys can tell like when I'm out and about like I typically use either my phone or my G7X. Because even though I love the G7X and still I like vlogging with it and taking photos. I like the wide angle. Like when I'm vlogging and stuff I want you know you to see the surroundings. Not that this is a lot of good captivating image right now. But like you know what I mean. So I don't know. I just really want that camera to sell. And then another like little side note thing. I don't know if I'm gonna do lips. Maybe I will because I want to take a picture. Also too I need more of this so I'm gonna leave this out. So all my curling iron is heating up. As you can see there's my two curling iron. My two curling irons once the wand I was saying. I got this new like road phone case. And I thought they were gonna be like more hype. Like I thought more people were gonna have them. So I got one because I'm like oh I kind of want to try and see what it's like. And I don't see anyone using one. And it's just like really big and bulky. So I'm gonna give it a few more months. Like I didn't even put it on my phone. Because like it's just way too big and bulky. I don't even know why I was like wanting it. It's probably just because of the hype. It costs way too much. It costs like 55 dollars. So I might try to sell it. I'll give it a couple more months if it's not like popular. As I thought it was gonna be. I'm either gonna sell it. Or I'm gonna try to do like a giveaway for it. Because there's no way I'm using that thing. Like let's just be real. I think it was just like more like the impulse buy of like oh I want it. I want to see if I can get it. And then I got it and I'm like I don't really regret it. I might keep the lip the peptide lip treatment. Because I might as well try that and use it. And I don't think anyone would want something that's not even in the package anymore. So I might keep that. But other than that I'm like the phone case is just not it. Sometimes my hair takes forever to get like the part the way I want it. Sometimes it looks like it's not in the center. And then sometimes it does. But I like a straight part. I love doing my hair with this because it's just kind of fun. And then after you get the hang of like wrapping it. And then I'm doing it like this and then curling it again. It's just so satisfying. Especially when you like when you release your hair like straight. Just watch. It's so satisfying to me. Look at that. I don't know. I like it. The only thing I don't like about the curling iron. And the same with my other one. Like you don't know when it's done heating up. I mean clearly I can tell like when it's hot.  So that's why I always like heat up the curling iron sooner rather than later. And then I also hate when my hair. See like it's not staying in the clip. So I have to like almost readjust it. If it goes if the hair is too low like in the barrel. It won't like stay clamped. Which I don't know why it's just super weird. And I don't like that feature. I wish it would stay clamped. Also fine too. I don't have to hold it for that long. So that's good. But yeah if the hair is like too far on the bottom. It doesn't stay. So I'm over here like hello. So basically I know this is an old technique. Which a lot of people on my youtube shorts like to remind me. Oh yeah this is this technique's been around forever. But my hairdresser. But my hairstylist basically told me this is like how to get the Dyson air wrap curl look. With using heat on your hair. So that's the reason why I do it. And see like this bottom part is straight and I don't like that. Sometimes I have to do this over again. Because the bottom doesn't get stuck. I mean the bottom won't hold. Because it's too far low like I showed you guys. So I have to go back in and like redo it. That one wasn't as satisfying. I've come a long way though with this. Because at first I'm like how do you do this. Was super hard and frustrating at the same time. But I have gotten better and faster. Okay so I'm just about done curling my hair. I will say maybe this is faster. Because I can like kind of take bigger chunks of my hair. And put it in the clamp. But when it comes to like the process of me turning this thing. I'm like slow. And I always need like two hands. The hair like slipped out. I hate when it does that. But the curl like looks good. So I can't complain. And there you have it. The curls are all done.  Maybe on this side. But overall I think they look pretty good. Okay so this is the final look. I'm not really wearing these shoes. I'm just gonna wear tennis shoes. But for the picture I'm gonna wear these shoes. Cause yeah I'm not wearing these shoes all night long. That's just not gonna happen. But yeah this is the fit. And I hope you guys enjoyed this little casual chit chat. Get ready with me. If you did give it a thumbs up. Don't forget to subscribe. And I'll see you guys in my next video. Bye.


Fibroblasts are the most common cell type of the connective tissues found throughout the body and the principal source of the extensive extracellular matrix, ECM. They are also the central mediators of the pathological fibrotic accumulation of ECM and the cellular proliferation and differentiation that occurs in response to prolonged tissue injury and chronic inflammation. Transformation of the fibroblast cell lineage involves classical developmental signaling programs and includes a surprisingly diverse range of precursor cell types, most notably myofibroblasts that are the apex of the fibrotic phenotype. Myofibroblasts display exaggerated ECM production, constitutively secret and are hypersensitive to chemical signals such as cytokines, chemokines, and growth factors, and are endowed with a contractile apparatus allowing them to manipulate the ECM fibers physically to close open wounds. In addition to ECM production, fibroblasts have multiple concomitant biological roles, such as in wound healing, inflammation, and angiogenesis, which are each interwoven with the process. This article was authored by Ryan Thomas Kendall and Carol A. Feigali-Bastwick. We are article.tv, links in the description below.