So look, you guys like today's video? Give it a thumbs up, consider subscribing. Everything we talk about is time sensitive. Now let's do a little quick Q&A, about 10, 15 minutes or so, and then I'm off to the beach. Funny bot. Who was the winner, the first winner again? I'll give it a roll, let's see. It was Tanuki, Tanuking, Tanuking Tama. Yes, that was the first winner. Nailed it again. All right, Jonathan, Jonathan, hey Rob, do you think Internet Computer Pro call could even sniff all-time highs again? What's a two-year play? I love the content. Look, even if it doesn't hit an all-time high, it just went up 109% in seven days. Does that mean that it's awesome just because it went up in price? No, we just talked about that. But I don't see why it couldn't hit half of it or a third of that, and even if it does hit a third of that, and I think it hit an all-time high of 650 bucks or something crazy like that, I always forget. So let's see, I think it's in the top 20 now. No, yeah, number 20. So let's see, it is now at, damn, it's 11 bucks. Wasn't it a couple of days ago? It was like seven? Excuse me, 460 bucks. So let's say it makes half of that. Let's say it's $230, and it's 11 bucks right now. That's not bad, I'll take that. And who knows if it's the next great thing of all-time, I don't know. Let's see. How's the surf in Puerto Rico? It's great. I hear gas chambers as a board breaker. I've surfed very infrequently. But I mean, it's not so much here in San Juan and the Rado. It's more like in El Rancillo, the big surfer town. Let's see, surf town. Oh, Rancón, sorry, Rancón, not Rancillo. So yeah, that's where most of the surfers hang out. I mean, they're really good ones, so. But you'd love it here. If you like to surf, this is one of the best places to be. And you know what else is great? You don't have to wear like a bodysuit like you do in California, because it's super cold. Not all the time, I understand, but over here, the water's always warm. Lax says, what do you believe will be the reaction? The ETF's not approved, and it'll probably dump. Mark will probably dump, and it'll be a bad day for, I don't know, maybe a day, maybe a week, maybe a month, not for sure. But the narrative's already there. It's already in place, so over time, it won't matter. If you think about it this way, if we get shot down in January, I think you'll see a dump, because then ARC is out. And the big narrative has been that Gary's going to approve all of them at once, so he's not a kingmaker. And if he doesn't allow ARC, which is January 10th, I think it is, I can't remember, then the next people in line are Black Rock and all the rest of them, Fidelity, around March, middle March. So if he denies that one, then I think he'll probably deny the March one. And then it'll be pretty bad for a little bit, but it doesn't matter, because he can't stop a halving. And after the halving, the narrative is already there. We've got other countries involved, so it doesn't matter. Let's see. Yeah, my back's improving. It's just, it's hard to sit down because of the herniation, the disc. Good luck, everyone.  Just kidding. Injective very drop season about to start, yeah. Injective and linear. If you guys are looking for information on airdrops, go follow Lady of Crypto. She's putting out some really good stuff on X and also on her YouTube account, Lady of Crypto. And yes, it's where I'm using her information and I'll go from there. But get it from the source. She's much better at that than me. Eth is the typewriter and so is the computer. Does anyone use a typewriter anymore? It still works. But why would you use it? It's true. I don't know. I mean, I've been around for long enough to know that narratives change at the drop of a hat, you know? So what is the darling of these last two months could be the next S coin of Q2 of 2024? So just be aware. Mm-hmm, I own stocks. Tesla and Microsoft and Mara, which is a Bitcoin money operation. Airbnb, not a good one. And Amazon, that's pretty much it. And then mostly it's in real estate. But yeah, I much prefer real estate. It's just a longer play, yeah. So this is, there's a website. I know everybody talks about this, about, you know, for Cardano and the transactions and they're right, it's not, look at this. There's a website I want everybody to check out. It's called eutxo.org. And what it'll do, it's a graphical representation of every block, of every block that's produced on Cardano. And within those blocks, you'll have different transactions, right? So this one is, you have 114 Cardano and NFT, one Cardano, this one here.  But you have to also be aware, the transactions per second, 2.45, real native Cardano TPS, 0.3, potential maximum output, 6.04. But if you click on this, the show spend or unspent UTXOs, it's quite a bit too. These are intra wallet transactions in red and in green, it's transferred to foreign addresses. So I know people will say, but, you know, the UTXO, and there's a lot more going on, there is. But, you know, when you're up in the 5 million range, transactions per second, does that mean that Cardano can't do something? No, it just means that right now it's, it is what it is. So we'll see how that works out. Hope that made sense. And what do you guys think about what I just showed you? Let's go ahead and see, I think. What about flipping real estate? It's risky and I don't really like doing it. I did it once and I lost my A, so. I'm good without that. Mark says, sell everything on Christmas day. Could be.  So after I sell, I step down for a bit and I don't come back and tell the bear market because nobody needs me in the bull morn.  Thumbnails with the mouth open and shock surprise.  And you won't need me because you'll be riding high on FOMO and adrenaline. And hopefully you can remember like, hey, there was that one guy who said he sold. He's not around anymore. Maybe I should take a look at some metrics. And then when the bear market comes back, I can say, well, I told you I wouldn't hit the top, but here I am again. Now it's time to start doing the hard work. Thuffer says, what are your thoughts on the Ledger hack? It wasn't like it was, it wasn't a hack where people lost crypto. It was, first of all, it was very weird that an ex-employee had access to their GitHub account and he was phished. And he was whatever the hacker was able to incorporate some malicious code and people when they were interacting with a DAP could have their wallet drained. And I think the data that I saw, it was less than a million dollars. But it is kind of concerning when you see something like that. I personally, it was a good thing that we saw that happen because it reminded me that cold storage wallets are just that, they are cold storage and we should never be interacting with DAPs. We should never be interacting with DEXs. If you want to get a DEX, there's a reason that you have a hot wallet. That could be a metamask, that could be phantom, that could be whatever you want that's in your browser and you can transfer it at the drop of a hat by using my favorite car, my favorite cold storage wall, which is the Tangem, just getting the address, putting it here and then doing this, done. And then it's on my hot wallet. I do the transaction, put it back, that's it. So I'm glad that that actually happened. I don't feel sorry for the people that lost that it reminded me of another rule that I need to incorporate, which is cold wallets are cold wallets are cold wallets. We shouldn't interact with anything else. Brent, you're good.  Actually, everybody here's gonna be fine. It's the tourist that I don't really, not that I despise them and I appreciate their coming in. But I made this analogy, tell me if this isn't true. If you go to a gym, you know that this is the last month that you get to where you can actually use all the machines and all the weights and everything else before the onslaught of tourists come, which is January 2nd, 3rd, 4th. There is so many new people that come into the gym that it sucks, you can't do anything because there's so many people there and you're like, crap, and you gotta be there. And it takes them one to two months to shake all those people out. And they're the ones that take up all the machines and everything else. I hate going to the gym at this point. But after two months, they all thin out. 95% are gone, 90, 95% are gone. They still have their membership, but only like 5% come back. And it's the same thing with investing. All the people in 2017 that piled in, there was only a few percentage that actually stuck around. I was one of those people. In 2021, everywhere that came in, the majority left after a couple months after the blow off top of the bull market, they're not gonna come back to the next one. So now that we're all here, we're the veterans of the gyms, essentially, and we're just waiting for the tourists to come back. I don't wanna deal with the tourists. So when this comes and we had a blow off top, thanks, have fun, good luck to you. Whoever's here in the bear market, I'll help you out. And that's it. It's the same thing and people don't change. I'm a tourist. I heard there was a pool. Ah, the deception. There is a pool just every day or so often I kind of flip things around. Yeah, let's see. Snack will get insane big with the ground option that's coming. I agree. And I actually own a bunch of snack.  Ah, man, I lost my coin out of my ETH wallet. Ledger will not respond. Yeah, that's another thing. Not a big fan of, you can do paper wallets and encrypt the USB and safety deposit box. Mark's right. This is very true. You can do paper wallets and hide in a safe deposit. And hopefully no, it doesn't get, the ink doesn't smudge or doesn't get wet or whatever else. That's not the future of crypto though.   I just would hope that there's a better product to bring people in. Of course, that product could also let a lot of people down. And that's what happened with the Voyagers and the Celsius and the FDX. That's where some taxes, first time here. Dennis, welcome. Taxes, hello. When do you expect FOMO? Oh, Luis, it's happening right now. Even I felt it. I've been around for quite some time. So when I see internet computer protocol go up, I'm like, ooh, I should just FOMO into that. And then when I saw a bonk go up like crazy numbers, I'm like, man, I need to buy more. Because I was in since November. And then name it whatever it is. But then I remember, I'm like, wait, wait, wait. That's not how it works. I gotta kind of slow down, get in later. I will tell you though, and we talked about this yesterday, is this the time to lump sum into some things? I think it is. I do think it is because if your time horizon is 18 months or less, or 12 months to 18 months, I think this will be the time to lump sum. Watch the video from yesterday. I'll explain what I'm talking about. You're gonna grave it on a metal plate? That's true. I just, whatever that metal plate is, keep it away from prying eyes. CTO Larson did a great video where he said, you need two cold storage wallets, one to interact with hot wallets and one that doesn't do anything. He goes, and it would be great if you have that piece of paper and it's in your desk hidden. He goes, but you know, it's just as easy as having a house cleaner come along and going, oh, what's this? And of course, as more mass adoption happens, you'll be like, oh, it's like a seed phrase.  You'll never be able to prove it. Just saying. Meme says, Bitcoin's in a boring correction time for all coin to shine, and it could really be. Could really be. Drone says, lump sum, I'm all in on my savings. Thanks, Rob, yeah? If you do it, just let you know. Tomorrow it could be a 50% drop. It is crypto, and that's it.  Is Algo even, I still own Algo. I don't even know what's happening. Let's see. I'm gonna guess, I'm gonna guess that not much. And yeah, I'm right. Got that one right. Algo is down 3%, but let's see what's been up. How's it been up? 14 days, 28%, and 30 days, 52%, it's not bad. Like I said, doesn't matter what you invest into as we move forward, you're gonna make it. Usually the price of most things go up, especially if you diversify.  That's really the only thing that really comes down to it. And that's it. So look, everybody, I gotta get out of here. It's been 30 minutes, it's past my time. But thanks so much for stopping by. I appreciate it, like today's video. Thumbs up, subscribe, all that good stuff. And I will reach out to you guys for the winners. That's it for today. I do appreciate you, and I'll see you guys on the next one. Have a great rest of the weekend. Adios.


Hello everybody. We are back again with one of my very favorite people in the world, Bob Miller. And we're going to talk about histamine today. So I'm super excited because I know many of you listening now or when you listen to the recording later. This is a really common topic that's complex that affects many, many of our patients and that I think will be relevant to you today. Now, if you know Bob and have seen some of our other videos, first of all, just for background, you can find all of them on my YouTube channel, which is just under my name, Jill Carnahan. If you search YouTube, you'll find them all there. I just encourage you to subscribe because you get updates when I post new videos like this one. And I think this is number four, right, Bob? I do believe number four, yes. Awesome. Very good. And if you haven't heard me introduce Bob, I'll just give you a brief background. He's been doing some amazing conferences, his company, Nutrogenetic Research. Is that right? Yes. Yes. Okay. And always dives into the pathways, the genomics and some of the mechanisms behind what we see as physicians in clinical practice. So I just find him incredibly helpful as an educator. And he does still consult with both physicians and patients. But he's a traditionally trained naturopath specializing in the field of genetic specific nutrition. He earned his degree at Trinity School of Natural Health and is board certified through the ANMA. And then in 93, he opened his Tree of Life practice and has served as a traditional naturopath for 27 years. Now in the past decade or so, he's really gone into this genetic research. And if you want to read more about him, his website is Tree of Life Health, it's tolhealth.com. And then the other one for all the research and the education is NutrogeneticResearch.org. So there's two sites. But the NutrogeneticResearch.org is probably where you'll find most of the events and education. Is that right, Bob? Absolutely. Yes. Okay. Did I miss anything else? Anywhere else people can find you? Well, that was it. That's enough. And you put on some amazing courses for physicians. So if you're a physician or someone who just wants to learn more, that's one way that I would dive in with the Nutrogenetic Research website and some of the education that Bob has there. So today we're going to talk about histamine, Bob. And I'm sure you have some slides. So let me make sure that is on to share. And if you want to share and dive right in, we are looking forward to this. Okay. Well, you know, we've been talking about histamine probably for the last 10 years. And what I find interesting is probably in the last couple of months that I began to realize that histamine is probably more of a serious issue than we ever realized. I'm just beginning to realize that it's not just, you know, your itchy eyes and runny nose. There's a whole lot more to the histamine. So let's just do a screen share and dive right in because I hear that all the time. People say, oh, I don't have a histamine problem because I don't have, I don't have an itchy eyes, runny nose. But that's that's just not the case. So let's dive into the slides here. And Bob, just to frame this just yesterday, I'm in clinic with a patient that we've had trouble. She's a young woman. She actually has a history of leukemia, but it's all controlled.  But she had a history of rapid heart rate tachycardia in response to foods and different things. And she saw cardiologists, she saw pulmonologists, she saw many, many specialists and no one could figure it out. And the common thing that we've been working on together and getting some really good traction in her case, excuse me, her case is histamine. So she went on a very low histamine diet and we're looking at other pathways. And again, some of the stuff you're teaching today, but that might be just for listeners, one way to frame it because you wouldn't typically think of someone who's presenting with your regular heart rate to be just histamine. And yet in her case, that was the primary issue. Absolutely. Okay. You see my screen, I believe? Looks good. Yeah. All right. So we're going to dig right into it. So histamine interestingly is a signaling molecule. So what a miracle we are, Dr. Jill, when you think about how the body was created, and we have all these signals that are going on and we're sitting around not knowing it's all happening, but underneath lots of communication going on. So histamine is an example of a chemical messenger that mediates signals or information between various types of cells. And there you can see the histamine with secreting cells, target cells, doing miraculous types of things. Now, histamine is very complex, and you can see by this chart, it can cause frequent heartbeat, blood clots, gastric acid secretion, causes blood vessel to dilate. That's why so many people might have low blood pressure. Bronchial constriction getting short of breath increases the permeability of the capillaries. It causes the histamine to be released and swelling and inflammation. All of those are controlled by histamine. It's part of what causes food sensitivities, but it's also part of tissue healing. It's also part of our psychological and cognitive health. It's involved with our sleep wake cycles, vascular functions. So, this topic today was the good, the bad, and the ugly. We need histamine, and you know in many of our talks before Dr. Jill, we spoke about too little or too much of anything is a problem. So, you can have too little histamine, you can have an adequate amount, or you can have excess. So, low, you could have neurological dysfunction, impaired tissue repair, because histamine's needed. You can have an altered immune response, reduced gene expression, reduced gastric secretions. When it's adequate, you're going to have good neurological functions. You're going to have good tissue repair. It will support your immune system, support gene expression, and support digestive and gastric functions. But like we often say, when it's in excess, we have a problem as well. Neurological dysfunction, actually what is used to repair the tissue in excess will cause tissue damage. Rather than healthy immune function, chronic inflammation or allergies, altered gene expression, and food sensitivities. One of the reasons I think I'm getting so excited about histamine is because we've spoken about this in previous of your Facebook lives, and that is we believe environmental factors are up regulating the mass cells that are creating these to be excessive. And we'll touch on that a little bit, but encourage everybody to go back and look at the last webinar we did. Now, many people talk about histamine, but they don't talk about this enzyme, histidine decarbolise. And this uses B6 to take histidine, not histamine, histidine, which is an amino acid, and turn it into histamine. So let me pull over one of my charts here. So we've talked about mass cells many times, and so many people are having increased mass cell activation. Then the HDC enzyme with B6 takes that amino acid, histidine, makes it into histamine. And then just to give the birds eye view, we're going to be talking about how we need cortisol to reduce the histamine. We need dinamine oxidase, TAO to break it down. We need an enzyme called histamine and methyl transferase. And something that people don't talk about very often is glucuronidation. That is another process that will reduce the histamine. So I think what we see happening today is that many environmental factors, and we talked about this in previous webinars, so I don't want to cover it now. I'd encourage everyone to go back. But we've talked about how environmental factors are stimulating the mass cells, stimulating the histamine. And those who may have difficulty with their adrenals, not making enough DAO, having weakness in HMT, or weakness in glucuronidation, are going to have high histamine. As we spoke about in our last broadcast, histamine actually comes back and stimulates the renin enzyme to create this whole process to stimulate the NOx enzyme again to make more histamine. We'll get into that. But I think that's why we're seeing such a rise in histamine, because environmental factors are actually causing that problem. So that's why some people have a negative reaction to B6. One of my coaching clients today, we talked about, they said, I feel terrible when I take B6 and practitioners try to keep going for it, giving it to them. Well, it was because they had this problem with the histidine turning into histamine. Now, here's what happens. Histamine is primarily synthesized in mass cells in the brain and in the stomach. And here's a little chart that shows your stored histamine and the induced histamine. And for time, we're not going to go through all of this detail, but someone may want to pause this webinar to just look at that chart a little more closely if they want to dig into it. Now, we've spoken about this before. Mass cells are a specialized type of white blood cell, and they're a critical part of the immune system, and they protect us from pathogens. Without the active mass cells, we'd die of infection. We wouldn't make it. God put that there to protect us. That's our immune system. However, as we've been saying now for a couple of years, we believe that environmental factors that we weren't exposed to 50 to 75 years ago is up regulating the mass cells. For example, Dr. Jill, how many people do you see now that you think have mass cells compared to 10 years ago? Yeah, Bobby, I always give the example of eosinophilic esophagitis, which is kind of an allergic type of pathway. And back in med school, we were taught it was a zebra, which means you don't ever see it. It's rare. We see that all the time now. And that's just one example of these types of reactions. Even the epidemic of GERD, or gastroestopageal reflex, which is also related, as you saw with the low production of stomach acid, et cetera, and many, many, many other things. I would say now at least 50% of my patients have some form of mass cell activation. That's a huge number. Absolutely. When I teach doctors, I'll have them raise their hands. How many of you are seeing significantly more mass cells activation now as compared to 10, 20 years ago? All the hands go up and everybody's like, yeah, what's going on here? So, degranulation from the mass cells is what causes that. And they can be triggered, as we said, by environmental and genetic factors. So, the histamine responses depends upon the receptor. So, there's receptor sites that receive the message. So, H1 receptor is involved in inflammation and allergies. And this is involved with the respiratory tract, vascular permeability. H2 is found in the brain, the heart, the stomach, and various white blood cells, which defend against pathogens. And again, this can stimulate gastric acid secretion, mucus secretion in the airways, and vascular permeability. So, but it also leads to relaxation of the airways and cells found in blood vessels. H3, only found in the brain, energy levels, sleep wake cycles, cognitive functions, and inflammation. And then H4, found in the immune cells along with the nervous system, and intestinal and lung cells. So, this can increase interest of their calcium of some immune cells for immune responses. And that might be a topic all of its own sometime to talk about how EMF is increasing the calcium. Now, there's an interesting enzyme called dynamine oxidase, sometimes called DAO. And this is what inactivates histamine, primarily expressed in the GI tract. So, that's one of the ways that we break it down. Now, I'm sure, you know, many people have been told, oh, you need to support your gut, eat these fermented foods, and you'll feel better. And for some people that work. But as you know, Dr. Jill, some people feel worse. And the reason being is they don't have enough DAO to break it down. We've had this conversation many times. Whenever you say that something is always good for everybody, be cautious, because everyone is unique. So, if someone tells you you're going to feel a whole lot better if you eat sauerkraut and drink kombucha and do miso, and you feel bad, that's possibly because you may not have enough of this DAO. And if we have time, we'll talk a little bit about how progesterone supports DAO, and there's other factors that break it down. And I don't have the specific research, but I've heard that long-term use of histamine blockers can reduce your DAO. Histamine and methyl transferase, this is the major metabolizing enzyme in the brain. And then there's MAOB that breaks down that N-methyl histamine from HNMT. So, let's just look at this graphically. So, here you can see the DAO enzyme that breaks it down. Here's HNMT, and then the MAO. MAO, any disruption along here, will cause your inability to break down the histamine. Now, I primarily work with genetics, and we look at the HNMT enzymes. And that's important, but people forget the genetics is just a part of it. Sammy, acidental methionine, is the cofactor. So, if you have perfect genomics on your HNMT, and you don't have Sammy, this is like a brand new car without gasoline. So, are the genetics important? Sure they are, but it's just a piece of it. That's why I call it the 3D chess game played underwater. Then, if we create mast cells, mast cells suppress HNMT, and then you can also have overproduction of histamine. So, is looking at the snips important? Sure. But is it just part of it? Absolutely. We just can't put all the emphasis on the snips. Bob, I just want to comment on that and make sure that our listeners are understanding the methylation process is part of the process that breaks down histamine, and the Sammy is one of those universal methyl donors. It's interesting because Sammy has a lot of uses. It was a universal methyl donor. The studies against SSRIs, almost all the drugs in that category, at 1200 milligram Sammy outperformed all of them. So, I frequently use it as an antidepressant.  And that makes sense in this realm of histamine as well, because histamine is about alertness and cognitive function. And just like we said in the beginning, Bob, love how you frame that. The good, the bad, the ugly. You want some histamine. If you have no histamine, if you're like me, I go comatose with benadryl, which is antihistamine. I literally am on the ground. I can't think, can't process, can't do anything. So, that kind of shows me what the lack of histamine does. So, it's this barometer. We want some, not too much. Absolutely. I often talk about goldilocks and three bears. Not too hot, not too cold. And that's where we need to find that balance. Now, this is an interesting paper that was printed in 2013. DAO activity was found to be greatest during the luteal phase of healthy women, maybe regulated by progesterone. So, that's why progesterone can be so important. This barometer, we want some. Sorry, Bob. Our audio got on there. We're good. Keep going. Okay. So, here's histamine and immune response. So, again, it's part of wound healing and tissue repair. So, when we get cut or something, we need to dilate those blood vessels, and we need to be part of the tissue repair. However, excess histamine may inhibit the wound repair. Back to that same thing of we need some, just right, and not too much. So, histamine can be released due to inflammatory mediators, signaling molecules, and histamine can stimulate inflammation and various inflammatory cytokines. By the way, we're really digging into cytokines, and I'm beginning to think that many of the things we're talking about, including histamine, might help you upregulating interleukin-6, which, again, is, you know, pro and con to it. But that's one of the areas that we're really excited about interleukin-6, and if we have time, we'll touch on that just briefly. So, it promotes wakefulness, regulates other neurotransmitters. It's part of our eating behavior, cessation. It may decrease the drive for consumption of food. It may have a role in the perception of taste. Hormone regulation. This was a new one to me as we researched it, seizure regulation, learning and memory, and coordinates communication between the immune system and the brain. However, aberrant histamine, various nervous systems, may have a role in neurodegenerative conditions. For example, low histamine, Alzheimer's, high histamine, Parkinson's, and schizophrenia, which all takes us back to balance, addiction, anxiety, and related psychological conditions. Now, one of the things I ponder, you know, just turn on the news for 10 minutes, and it's pretty clear that a lot of people are becoming very unglued. And I have to wonder if, you know, these environmental factors that we've been talking about is not just globally raising our histamine levels, just pondering them. Now, here's a study from 2008 that mass cell deficient mice had greater anxiety-like behavior. So again, back to mass cells, they're not bad. They need to be balanced. Inhibition of mass cells in the brain was found to increase anxiety-like behavior. Isn't that fascinating? We tend to vilify these mass cells, but the right amount of them is very important. I want to comment with the viral pandemic. We can't stop hearing about that. But viruses are shown in the literature to cause induction of histamine release through interferon. So when you get sick with a virus, whether it's cold, flu, COVID, whatever, you don't feel well. You feel malaise, fatigue, sometimes fluid or a fever. And all these things are instigated by interferons in the body, and that can cause release of histamine. So it's actually, I loved your commentary on the environment and what we're seeing and people kind of coming and glued because again, this is at play and the infections that are hidden, whether they're overt like COVID or other hidden infections that people are suffering with, they are playing with our mass cells and our histamine regulation. Absolutely. Now, I found this absolutely fascinating. Insufficient histamine was found to decrease histamine in the brain and induce that anxiety like behaviors. And then the monamine neurotransmitters were found to be unchanged. So again, we go back to with histidine. And by the way, we'll list the histidine foods. We need histidine, but in excess can create too much histamine and inflammation. So here's another one. Excess histamine may have a role in inflammation and neuro inflammation again with psychological and neurological functions. So that balance, if anybody wants to take one thing away from this whole talk, we need balance in just about everything. So lower concentrations of blood histamine have been found in Alzheimer's. Individuals with an APOE4 allele appeared to have significantly decreased levels of blood histamine. Now, interesting. It's been found to induce wakefulness within a variety of animal models such as Cedalcholine, serotonin, and norepinephrine. The responsible for an estimated 50% of the histamine in the brain, mass cells also appear to have a role in sleep wake cycle regulation via histamine release. But it's no surprise, complex. So that's why antihistamines can sometimes cause drowsiness as you just pointed out earlier. Now, interestingly, histamine levels in cerebral spinal fluid have been found to be decreased in individuals with narcolepsy. Isn't that fascinating? But again, it goes back to the histamine may have a role in promoting wakefulness. Bob, you and I are so in the same wavelength. As you're talking, I was just checking in the research to see if medaffinil could cause increase in histamine. Medaffinil is a drug used for sleep wake cycles and for excessive daytime sleepiness and narcolepsy. And we don't know exactly how it works, but we think it releases dopamine. So it's dopaminergic. However, it also releases histamine. No surprise because this is a drug that's actually used in that excessive daytime sleepiness or narcolepsy. Wow. Fascinating. Now, look at this study on histamine and methyltransferase. It's broken or that histamine is primarily broken down by H&MT in the brain. So H&MT has been also shown to have a critical role in normal sleeping patterns and aggressive behaviors. It's the same pattern evolving all the time. It can be helpful or harmful. And just as a clinical observation, when we do our health coaching here, we see folks that couldn't find help elsewhere. Many, many times, they have lots of homozygous variants in their H&MT genes and they're sensitive to heat. They're itchy. Their brain's racing. If they take a hot shower, they get red. Mosquito bites, massive reaction. Histamine foods. A glass of wine can send them off into all kinds of anxiety. So plasma histamine levels have been shown to display elevations in the evening. And the varying histamine levels may be due to regulation of the circadian rhythm in mast cells. So one of the areas we want to be looking at soon is that circadian rhythm and the clock genes. Fascinating. Now in the stomach, it's released as a response to food consumption. And HDC expression, that's the histidine decarbalase, appears to be regulated by the hormone gastrin. Now it also has a role in intestinal motility and the ability for your digestive tract to perform critical functions. How many people are having digestive issues? It's rampant. So if you've got poor gut health, you very well might have low DAO. It's found in the villi of the epithelial cells of the small intestines, which is critical for the absorption of digested nutrients. And then when the villi are damaged, malnutrition can ensue. So since DAO activity decreases as intestinal mucosa is damaged, that DAO activity might be an indicator of any intestinal mucosal damage. And just, again, clinically observing when people have difficulty with gluten and histamine, these are many of the people that get autoimmune diseases like Hashimoto's because of the leaky gut. I'm sure you've observed that as well, Dr. Jill. Yes, absolutely. We use DAO enzymes frequently and some people really, really benefit. And I would say the majority of them have had either inflammatory bowel disease, significant SIBO or SIFO, which is bacterial or fungal overgrowth in the small bowel, which are causes of damage to the microvilli or something like giardia or some parasitic infection or celiac disease. Absolutely. Now, let's talk about excess. So contributes to chronic inflammation. So during acute injuries, inflammation is the body's way of initiating repair. However, stating the obvious, unresolved or chronic inflammation can disrupt that homeostasis and may contribute to many conditions. And histamine has the potential to contribute to this chronic inflammation and prevent the body's ability to heal. Now, I'm going to mention this towards the end, but in case somebody doesn't watch the whole podcast here, we spoke about this in our last Facebook live where histamine blows me away, comes back, stimulates renin, stimulates angiotensin one and two, which then can stimulate interleukin-6 and aldosterone, stimulate this enzyme that makes more mass cells and around and around we go. Yeah. And Bob, I see a small percentage of patients that are literally stuck in this cycle and they might be bedridden. I mean, I've seen young people, 20s and 30s, even younger. And I've seen cases of complete alopecia, which is hair loss like baldness at 14 or 26. So, and that's also histamine related in some cases. These are things you may not think about. Like you think histamine, oh, stuffy nose or congestion, this can be completely incapacitating and cause disability in patients. Absolutely. And that's why I'm looking at it more closely. So here's nonspecific, some things you were just mentioning. Congestion, difficulty breathing allergies, the obvious. Eczema, flushing, itchiness, swelling, rash, flatulence, bloating, abdominal pain, diarrhea or constipation, nausea, leaky gut, food sensitivities. And I'd put on there the inflammatory bowel diseases as well and then headache and dizziness. Now, what are some of the sources of excess system? The high histamine foods, mold exposure, you and I are both on that same page, serious problem, allergies, certain medications. And then these are the genes that we're going to talk about, the histamine receptors, the histidine decarbulase, the histamine and methyl transferase, the ABP1 that makes the DAO and the MAOB. So in my opinion, knowing how these genes are doing is a pretty critical factor of understanding what you have to attack. This is just a couple of slides. This is what they look like. Here's the histamine receptor one, two, three, and four. And I think most people know this, but when there's a one, that means one parent gave them a genetic mutation. And if we see a two, both parents did. So here's HDC. And this is the one that I'm really fascinated with. I am seeing when people have mutations in HDC and mutations are an up regulation, meaning it aggressively takes histidine and turns it into histamine. Just as a side note, this is my own personal health challenge. I was having a flare of digestive issues through everything but the kitchen sink at it. And this is just in the last couple of months. And I found that this was being up-regulated. So I did reduce some of the histidine foods, took some of the things that calmed down histidine, and within days, resolved. Totally amazing. Now that's not for everybody. That was for me. And that's why we can't save the pill for the ill. Now here's the histamine and methyl transferase. And every once in a while, I'll see people that there's twos all the way down through there. And they just cannot clear histamine. And of course, as we said, we need sami. So again, you could have perfect HNMT. No mutations at all. If you don't have any sami, it's the new car without gasoline. Yeah. Bob, I just want to mention I love that you shared your personal little bit because people love to hear it. It's so practical. And just if you would have known me, severe eczema as a child, severe asthma as a child. And then all of a sudden I realized like bone broth and fermented foods and kombucha and dried jerkeys and smoked salmon, all these things made me rashy. So it's no wonder again, we don't know exactly which genes I have, but the same thing I found. I never had heard of the low histamine diet. I just by nature, gravitated towards that over the years because I knew those foods weren't good. And then one day, maybe five or 10 years ago, I realized, oh, they all have histamine because a lot of the foods that you're, if you're listening, you just joined in and you thinking, you need to eat bone broth. You need to eat fermented kombucha and sauerkraut and kimchi. These are great foods for the gut, but guess what? They have a load of histamine. And if you are intolerant to histamine, you will not do well on these foods. And I never forget the expression on some people's face when they're saying, you know, I started eating healthy and I did things that are supposed to be good for me and I'm feeling worse. Yes. You can just see the expression on their face when it's like, oh my, I was doing all these things that helped and they hurt. Again, like you said, bone broth. Bone broth is also high in glutamine. Yes. Well, if you've got high glutamate, the last thing you want to do is take more glutamine. And interestingly, my first health coaching client this morning, same thing, extremely anxious and was doing all glutamine for the gut, taking GABA, drinking bone broth. Wow. And you could just see the expression on her and her husband's face when I said, well, I think you're going to feel a lot better when you stop doing that. Yes.   I know. Well, I just want to acknowledge, I mean, people listening, you have heard hundreds of different people, different, you know, platforms talk about this and that it gets confusing. So this is where, I mean, I love anyone's listening here.  You might be a physician who wants to know more. So totally love that, but you really need someone who knows what they're doing to help guide. I, like I said, I love talking to colleagues like Bob, because I always learn more because sometimes navigating it yourself can be very confusing. Absolutely. ABP1, particularly this first one right here that ends in 793. Mutations on this one, heterozygous, meaning one parent, will reduce the DAO. So I've never seen anyone that has a two on here that didn't have a serious histamine problem, that all the histamine foods were a disaster for them. And these are the people that need to reduce their histamine foods and also make DAO enzymes their lifetime friends, because they just don't make enough. And many of these people are just sabotaging themselves unknowingly, you know, thinking their gut's upset. Will I do more of these fermented foods? And they're feeling worse and worse. Now, don't go away from this saying I'm against fermented foods. They have all kinds of tremendous benefits if you have adequate DAO. And I'm going to mention this, that copper is a cofactor. And many times we see people with genetic mutations in their copper transports. So therefore, they don't make enough DAO despite what's happening. Now, this was a an interesting study during a small clinical analysis, 10 out of the 14 participants with symptoms triggered by histamine-rich foods were found to have reduced DAO activity. Not a great surprise, but it's nice to see it published in a peer-reviewed study. And, you know, here's what it looks like with a healthy individual. And then here's histamine intoxication. And then here's histamine intolerance. So this could be from an external histamine or not enough of the DAO enzyme. Now, this is the histamine-rich foods. Wine, champagne and beer, sauerkraut, vinegar, anything fermented. And by the way, that can include fresh fruits that have been sitting in the refrigerator for a couple of days.  This one surprises people, nuts. Just had a client a couple of months ago that ate nuts all day thinking they're good for him. Stopped the nuts, felt better. And we tend to think avocados great for that ketogenic diet. But however, if you've got a histamine intolerance, it can work against you. Eggplant, spinach, tomatoes. If I have a slice of tomato, I'm sneezing for the next 10 minutes. Wow. Anyone want to explain two real quick things? There's some in that vegetable category that look like nightshades. There's eggplants and tomatoes. This is interesting because I'm the anti, I don't do well with histamine. So I cannot eat eggplant, avocado or tomato, but I can eat peppers. So it's not a nightshade issue. It's actually more of a histamine issue. And that might help you if you're struggling and you know you can have peppers, red or green peppers, but not eggplant or tomato. That's not a nightshade issue. That's more of this histamine issue.  And so they get converted into histamine. And how that happens is when they're aged or smoked or they sit in your fridge as leftovers. So that's why one night your fresh steak dinner or your fresh seafood dinner is wonderful, but leftover two days later, it makes you react. And this is also why if you get flash frozen fresh fish from Alaska, you're going to be fine. But if those fish were not frozen quickly at the site of where they were caught, you might react to them. Or if you're getting good whole foods and the fish counter and the fish have been sitting there for a couple of days, you can have an issue. So if you have histamine issues, fresh meats are really important, fresh proteins. Absolutely. I've heard that many times. I had a meal, I was fine. I had it later and I had a reaction. Then you ask them, was it sitting in the refrigerator? Yes. And you can see their eyes like, oh. Exactly. All right. This is 10, top 10 histidine rich foods. Interestingly, things like pork chops, beef, chicken, tuna, tofu, navy beans, milk, nuts and seeds, grain and eggs. So these do not contain histamine, but they contain histidine. So if your HDC is up-regulated, you can see here on the right, here's histidine, here's the histidine decarbalase and histamine. Now, evidence-based nutritional support, a low histamine diet may be beneficial for individuals with those sensitivities. And one of the things we've been really digging into is lycopene. And lycopene is in tomatoes. So if you cut the tomatoes, you could be low in lycopene. And, you know, we've known about this because we've dug into this. Lycopene is a really important antioxidant. So lycopene consumption has been inversely associated with all cause mortality. And many low histamine diets may be eliminating or reducing the lycopene consumption. And I often get asked this question, if we give someone lycopene, they'll say, well, that comes from tomato. I shouldn't take that. No, that's just a molecule that's taken out and does not have histamine properties to it. So we've become big fans of lycopene. So here's a study. Low histamine diet for six to 12 months was found to result in a 100 increase, 100% increase, in DO activity in participants who previously had reduced DO activity. And then their histamine intolerance disappeared because they're allowed their body to catch up. Low histamine, oh, this is a repeat. Okay. So grilling and frying foods was found to increase histamine content of various foods. While boiling the foods was found to have no impact or decreased histamine content of the selected foods. So here's another study. During a clinical analysis in healthy women, dietary fatty acids and micronutrients were positively associated with DAO. So long chain fatty acids and monosaturated fatty acids. And plus phosphorus, calcium, zinc, magnesium, iron and B12 all supported the DAO activity. Now, as we mentioned earlier, this is a copper dependent enzyme. And two milligrams for four weeks was found to increase SOD because superoxide dismutase of course is also copper dependent and DO activity in male participants. Just interesting clinical observation. Many people of Irish descent have a lot of mutations on their copper transporters and pure speculation. But I have to wonder if that coppery red hair might be the copper coming out rather than being utilized. Just want to Bob Miller's musing. So we should probably study that sometime. I love it. And I want to comment because zinc and copper are antagonistic. So I often use zinc in young women who have access estrogen and copper to bring down the copper. That's actually common. However, as we age, if women are no longer menstruating, and of course men who don't typically have a monthly issue with blood unless they have colon issues, often could be deficient in copper. And so this is worth checking. If you're a clinician in your patients, if you're a patient asking your doctor to check copper and zinc can be really, really important. Sure. And you know, one of the things we've found sometimes is that plasma levels of copper can be good, but red blood cell is low. Yes. So I'm a big fan of looking at red blood cell. I am too. And just a clinical comment, you can ask your doctor to check RBC zinc, RBC copper. And I do that frequently in my patients. Excellent. Excellent. Now, DAO was found significantly to reduce histamine-related symptoms in participants with histamine intolerance. I mean, that's kind of like a duh, but they did a study to prove it. Here's another study. DAO supplementation was found to reduce the severity of headaches when it was related to histamine intolerance. Now, quercetin is an anti-inflammatory flavonoid that actually inhibits HDC. That's possibly one of the reasons why quercetin can be bringing down the histamine. Perhaps there's others. Also, EGCG, what's found in green tea is shown to inhibit HDC in research parameters and may have anti-inflammatory properties. Now, additionally, we just couldn't find the research on it, but testosterone and iodine also inhibit HDC. So, particularly now in boys, as testosterone levels are dropping and estrogen levels are going up, could this be why college professors tell me that the young boys coming in are so fragile? They get upset quickly. They need their safe spaces, and it's not necessarily their fault, but if their testosterone is going down and their histamine is going up, then, of course, testosterone also supports COMT, the clear dopamine. So, we could theoretically be seeing higher histamine and higher dopamine, you know, creating some of these emotional issues. They're now becoming so popular. So, I'm going to wrap it up here by showing again the home cycle. And again, we talked about this in our last webinar. So, I encourage people to go back if they want the whole details on this. But just bottom line here, here it illustrates how histamine comes down, stimulates renin, stimulates angiotensin 1 and 2, that stimulates interleukin 6, aldosterone knocks more superoxide, more mast cells, more histamine. And then if we have glutamate that will inhibit ACE2. And here you can see mast cells, histamine, dopamine, testosterone stimulate the renin enzymes. And many times when people have high aldosterone, they'll have higher blood pressure. And they'll have edema because aldosterone causes them to hold on to sodium and excrete potassium. And so, I oftentimes ask people, do you at night time when you take your socks off, see an indentation? And I'm seeing that in people in their late 20s and early 30s, they're getting edema because of the aldosterone. And as we support ACE2 that will reduce the aldosterone. We've seen many people drop waterway very quickly. And then the edema goes away. And of course, we all know that ACE2 is used by COVID. That might be one of the mechanisms that allows COVID to be part of that cytokine store. Yeah, I mentioned this before, but when I had the mold illness, I had severe 3 plus pitting edema.  And this was for a couple years. And I know that this pathway, because of mast cells, because of mycotoxins, stimulate that cytokine. I probably had elevated IL-6 as well. And I never measured aldosterone and renin at that time. But I'm assuming this was a big part of that pathway. More than likely. Yeah, more than likely. So here I just wanted to show how the mast cells give off the cytokines, the IL-13. That's a whole another subject, IL-13 and the histamine. So here's the study that shows the role of histamine receptors in the release of renin. So we always make sure everything we say that has papers behind it. So histamine has been shown to stimulate the release of renin in multiple analyses. So to me, I thought that was an incredible clinical pearl, that histamine will stimulate renin. And then this is a paper that not too many people talked about. And again, I won't, where it looks like we're just about out of time. But this also talks about how we create this cycle that just keeps feeding itself. And that's what I've named the home cycle. And that's what this paper was was focusing on. This should be in reading for just about everybody because I think it's what's what's going on. And then finally, just a quick hormone relationship. The estrogen will stimulate the mast cells, the mast cells will stimulate the histamine. The histamine will stimulate the estrogen and around we go. And that's why making sure we're not an estrogen dominance is so important. And it looks like we ended on time. If anyone wants our clinic, there's the information health professionals only. DNA supplementation.com is where we have the online certification course. There's the contact and some of the nutrition that we make again for health professionals. So sorry if you're not a health professional. We can't we can't help you out there. So there you go. There's our 45 minute presentation on. Bob, you are right on the die. And first of all, I just as always, I always learn new things. I know if you're listening here, you have learned some new things as well. And I hope I just saw questions coming in. I'm going to go back and answer those. Maybe a bottle pop in as well. But I loved your interaction today. And if you listen to this recording, post questions, we'll pop back in there again, visit the YouTube channel. And just a little plug, if you want to know what I dressed up for Halloween for this year, you can check my Instagram at Dr. Jill Carnahan. There's a photo there. So you can see what I just literally ran out of the office change clothes. And I'm no longer in costume. But if you want to see what my costume was, you can pop into Instagram and check it out. Bob, thank you so much. We're going to do this again.  And Bob, we are so grateful for you. Thank you for your time, your expertise. And just all that you do for the world for practitioners. I know you and I are unified. And if we can teach practitioners, we can help more patients. So this is a great way that we can do it. And thank you again for joining us. Well, my pleasure, like always, it's a lot of fun. I always look forward to it. And thank you for the opportunity for the platform for helping people understand this. You are welcome. Have a great afternoon.


This video is brought to you in part by TrueTechTools. Quality tools, essential support. Hey, what's going on everybody? I'm going to be working on multiple different pieces of equipment. Was there with the mindset of replacing a compressor. Had to look at the air conditioner. It had issues. Then we got to throw in another problem with another walk-in cooler. Then we have a walk-in freezer. So all kinds of things to go wrong and they all kind of did. You make mistakes. You're not thinking clearly. You get kind of stressed out that you want to get done in time and squeeze it all in one day and that just doesn't always happen. Anyhow, give the video of you. Cut me some slack. Let the video begin. So today we are out here for three issues. Got a packaging here that's not working very well. I guess we may have just replaced a TXV on it.  So we need to check air flow and stuff like that. And then we have a compressor to replace on one of these walk-ins. And we have a hot gas line to replace in a condensate pan. First thing I'm going to do is start with my filters and belt. Make sure all that stuff's okay. I just killed the power because of course if it don't work keep on running it. It's froze up because of that. This one here has a solenoid on the liquid line that basically shuts down half the coil. It's a single compressor with a high-low unloader built into it. And it looks like we have a fan cycle control down there too. Looks like we still have the high-end free filters that come with it. Quite a bit of ice there. Not horrible is what it looks like on the outside. Looks on the outside. It's got ice all the way out on the one edge. Probably just go ahead and just let the fan run. Anyway, self defrost. Always love when I see oil at the bottom here. I don't know if that's left over for manufacturing. Looks like we got oil all through here. Got it through here. Looks to me this is probably it. Runs but it doesn't pump. Usually the same person comes back to replace it but because it's out of the area and closer to where I work out of, I got it. This must be it because the contactor is burnt like I was told. See that's not in the greatest of shapes. It's got heated defrost. Clock feels free. Got a fan cycle. Not sure if they voted button new refrigerant in this or not. My preferred method is always new. Here's the evaporators for that particular section. These ones here are all clean. We got these two over here kind of carrying the load. This is what's on the other condensers so at least we know what we're working on. The air conditioner comes in across the ceiling out through the convenience store area. I'm going to pop this out, the accumulator, and dump it out. If we got a bunch of oil in it, I'll remove it for now until we get a new one in there. We have a sight glass down here on the oil. I've wiped it off and tried shaking it. I cannot see oil level. A couple of things that's been talked about in the past is always a good idea to dump the oil out of it and measure it that way you know whether or not oil returns an issue. Also worst-case scenario what I'm going to do on this one is like I said I'm going to dump this out and see if there's a bunch of oil in there. If there's a bunch of oil in there then the little u-shape bend here has a seep hole in the side of it. That probably is getting plugged up and not returning the oil.  That indicator should have been replaced. First thing we're going to do is we're going to check our compressor data tag here. Make sure that it matches up or at least we'll cross over to what we have on the unit. We've got a 45k. We want to make sure that the voltage is the same 200 and 230 volts. It's three phase. There we go. Looks like a 45k. While we're waiting on this we'll go ahead and get this contact changed out real quick. Power is off. Talked about these before. They've got a really nice crimp and a relief crimp. These connectors we've got too many of them in there. They're not fitting for squats. So what I did is just stripped it. I'm going to go ahead and get that all underneath one and it makes a good crimp. You can see it completely flattens it across the front to back there. It benches the outside inch corner there to there. It makes it fit a lot easier and now you can get right on to the terminal. Now we're not nearly shortened into one another versus three of them back here. I'm not a big fan of running it through that without a Romax connector but it is inside the box so theoretically it's probably fine. It only took about five to ten minutes here and we're well down to 15 pounds 12 ounces. I think we're done. This gauge I know this is off by quite a bit. Yeah we got it out of course pulled there and there. So it took quite a bit to get this thing to break loose. I don't know just naturally seized on there or what. But when we do put it back on we'll twist it up like that and so when we go forward it should wine back up. Normally I sweat these out. It just depends. Manufacturer says don't unswet them. They're working on R290. Definitely don't unswet it. I'll take them out like this but don't put them back on like this. Good way to snap it off. These are numbered one two three. One two three. Okay we've got our cut there. I'm going to unswet here. Cut there. Unswet here. Slide it up. It's easier to pull down than it is to pull up. I want a nice clean joint on the bottom. Kind of reverse logic for this one. I just basically am so close to that 90 that I don't want to deal with trying to remake it. Everything came apart just fine for me. Just heated it up, pulled her out. I'll run nitrogen on the next go around right here. I really didn't get anything built up wise in there. If I do I always carry a little brush. I'm able to brush out anything that might have carboned up. Just depends. I mean you're in a hurry. You want to try to do it right. Same time you've got little things that will make it just simpler. Just clean it out. Move on. Fan blade. Look at that. Got a fan blade that's broke. So that would have been your next problem. Well we're gonna have to order one of those now. Hopefully it don't fly apart and cut the coil. Looks like I replaced the defrost, heater, lockout relay, suction dryer that was leaking. Well 2016 so it's a few years old. Should just left it out. 26 pounds and I only pulled out 15-ish, 16. That's great. That's that's always good. So we probably have a leak too but this thing started up in 05 so make her last another day. That might have been those evaporators that were changed. They probably were old ones that were leaking. Now the problem's fixed I hope. And let's see if we can see that oil. Up there it is. Let's see it when you tilt her forward. So she's not completely empty. That there unfortunately is locked in there pretty tight. They needed to put that bolt on the bottom and there's no good way to lift this thing up. I don't know if I can pry that up or not. We can try to get on there with the crowbar. Make this a little easier. Go ahead switch that out. He's able to expand that. It's going to make it nice and easy to drop that right down into it. We were able to pry it out through the bottom. There was no way I was going to be able to lift all this up.  I'm not messing with all that and it's a 2005 unit. Went ahead and pulled it through.  It don't smell burnt. I think we're probably going to be all right. The compressor would have been completely empty. It was a little low looking. It could have had suction dryer on there from when it was factory installed and then it had just been before. Some of the time I started but we're probably just going to go ahead and use this over. It was kind of a place to start. Kind of you know just double check and make sure. Took my attitude adjuster. Got it back into the spot. Took the nut off the bottom of that. It's not going to go anywhere. If it does we'll put some foam stuff underneath of it. Cork tape whatever but that will work there like that. At least we checked it. Really like to see a nicer sight glass but no this was really quoted so I'm trying to keep costs down. Spaceship we end up doing all new refrigerant which I am leaning towards doing. I really hate reusing refrigerant. Can't tell me something didn't go wrong when that thing snapped off. Why does it snap off? I mean granted it is getting older is 2005. What do you do? Got to make a judgment call here. Probably going to give that refrigerant a sniff again and see how bad it smells and kind of go from there. All right so can't help but notice this little problem. See that? Yeah that's not normal. So I don't know if it's just getting hung up or what but looks to me. Feels like it's energized.  So it's calling to be open so it's restricted. Probably going to take it apart and clean it. Pull the solenoid off there and see it open and close it a couple times. You know it's going to do it again.  Yeah that's not just started. That's been going on for a little while there. So it pumps down. It's just restricted. Spectacular. Okay let's take it out now.  Okay they're just coming up. There we go. All right so I didn't really do a whole lot of good. We can do here because I had to add that valve a long time ago. We can check.  Like there's actually a leak actually leaking through the schrader core. Why wouldn't you just replace the schrader core?  Okay so we are running 176. Over here that's a little little restricted ain't it? Yeah nice. Got everything prepped ready to go. Got the compressor loose but in place. About ready for that to be put on. Got everything sanded up. So we're going to go ahead and get the compressor section connected first and then we'll work our way back to here. Okay we got our nitrogen flowing. We're going to purge through there. I don't want to open up my valve here because I've got blue tape on it because it probably freaking was leaking. I went ahead and got that braised there. Got to pull down into the pocket there. Lifted up just a touch for there and it would be good to go. I don't have my tripod with me and honestly I'm running out of time. This is taking way too much time because everything's freaking broke here and I got to fix everything. So it's taken a little bit. Actually with the way that's kind of bent down like that it would have been a little bit of be fine. Got the wet rag on there. Got it down as low as possible that way you can pull the heat down into the socket and then we just purge through at auction. Shouldn't get back in there. You ain't going to have enough that's going to make up a deal and we're on this side of the desiccant so we should be good. Let's go ahead and get this done just like this. Got it all braised in.  Make sure we can inspect it clean. Make sure it's clean and good. Use some of the putty stuff on there. I had to regenerate it because it's getting a little dried. I'm going to hit that with some of my gray paint stuff I've got similar to actually I don't know if I what I used on that one long ago but it's hold it up pretty good held up held it up hold it up whatever. So when I checked all behind there we was able to pull the nitrogen through that direction there. At the compressor it's a little tricky but you know other than that everything's been done to the best uh industry standard possible. We're going to get to pulling on a vacuum on this and I need to start working on this air conditioner because it's getting pretty warm inside there. I didn't want to do it while the system was still open we can finish tidying up the electrical after we're done with that air conditioner. Clean those threads up a little bit because those things are not very good. This video is brought to you by refrigeration technologies and your friends at true tech tools where you can buy all your favorite tools and more with discount code survival at checkout to save even more money. Yeah there we go. That was live. We did that live. Do you guys ever watch my live streams? You would have heard that I used to be a mobile DJ. That's right ladies and gentlemen not only in my HVAC technician but I was a DJ disc jockey guy since 1991 when I was a freshman in high school and started around sound when I was 14 so there's a magical trivia for you. I like how that fit on there. Wires are straight. Everything's wonderful. Presentation is everything. Only second to operational.  It happens. I should have ran that up underneath there. I'll attach it to that and then to this that way and ain't rubbing on the discharge line. Now you've seen the magnet but why do I have that little clip there? That's for like trailer hitches and stuff. Well first of all okay we've got that there but what happens if you make a mistake? I know we've never made a mistake before.  That holds in there really good.  I haven't really had it tested yet but I guarantee it's better than not having anything in there and it will melt down in less than a couple minutes. Handy dandy trip tip of the day. All right gas valve is open and we are starting to pull down. Let's see how fast we can get this thing down. Start of the stopwatch and like I said we've got everything closed up on the compressor I believe. Looks like it. We got our solenoid. Click a ruin. Now if this thing truly does hold 20 some odd pounds that one air held 17. I think we're gonna weigh it in slowly though because with those new evaporators it could be completely different now. Okay we are almost two minutes in still not dropping much. We are coming down on the bars there on the end but you gotta remember we are pulling against a large receiver which is bigger than the compressor here. It's a hungry burger and it's going to sleep wake her back up. Two and a half minutes. She's boogieing down. While it's doing that let's go over here look at this. We're starving this system. It needs a new solenoid on it. I'm gonna have to do that for 10. Got the probes hooked up to the liquid. We'll go ahead and run it. The pressure seemed off so it may not be what I was originally thinking. The belt looks tight. What is that? Grease? Don't like the fact that we didn't put an economizer on it. I don't know how much more but whatever. We've got a fan cycle control at least on there. That pulley looks like it's kind of slow. I wonder if our problem is we're not moving enough air flow. It's a pretty good sized store. I'd be really surprised. Let's see where our amp drone stuff is at. So far we're running about a 44 and a 106. I don't know what our outdoor temperature is yet. Let's take a look. We're slowly building 25 degrees subcooling, 9 degrees super heat. So far things are looking pretty good. While I was at not working is it because we just don't have the speed? Definitely that wasn't that great. That definitely needs to be fixed. A little spare. Seven and a half pounds. Let's go ahead and put these high quality filters back in there. We really need to get this washed off quickly. I think we had a sprays position over here. Boy that's just that's just terrific. That is really terrific. No super heat. That ain't good and not good. Subcooling is 28. We're running 630 some pounds of head pressure. That's definitely not good. I'd say that's probably a problem. What would cause the head pressure to be so high? I would say probably overcharged. Very possible. We have no super heat. So we got 41 and 41. So we got pretty much zero. Subcooling we're at 29. That's not how these are charged but it's still the same principles are there. We're at 16 minutes area. We're at 1600 microns which kind of slowed down there. I just recently took the cast ballast and closed it. Oil's not looking horrible. Looks a lot better what it did earlier. May need to do it oil change. May not be a bad idea. I think it's been a while since I've changed it. All right so it's not running this fan here which is probably why it's running at such a high head pressure. Now look at us we're around 300 and something so we must have dropped down. Super heat's coming back. That's that's craziness. I'm going to say we need to check and see whether our Y1, Y2 terminals are calling if we've even got a two-stage stat on this thing.  Okay this is a bumbling mess. You've got Y1 and Y2 going straight to it from here. So here's where we're at. We brushed that off because I haven't found the water spigot yet. I thought it was somewhere near here. Anyhow head pressures came down. Here I want to show you something we got going on. Look at our evaporator it's running 25 degrees and 102 on our condensing. We're right at about 15 degrees over. So we've got a solenoid right here on that liquid line. So I wanted to check to see if we are energized which we are energized. We're rolling right at about amps but look up here at our suction line at the top here. I think this is why the TXA was replaced. We had something very similar but this is with a door off. I mean this door off we should be like skyrocketing high head pressure. Right here. Can you feel this liquid line? It is not warm at all. Both of those are hot. Hot gas is hot. We're running below freezing.  Now we've got this here which is two-stage solenoid. Let's see if it's energized. I think what we got here is a bypass module for this pressure switch which I've only seen that on heat pumps. Let's come down here and go to Y2 common. It says we are energized. We should be anyhow. So we've got Y2 going on there.  Okay I guess they were given an option for an economizer. They didn't want to do that. So strike on them. Here is some of our stuff. Compressor, door fan motors. So our voltage on our unit is 211. We're set up for 240, 30ish or 208. We're touched over. If you go R to common we're running right at 21 volts. That's real great. So let's fix that. All right now we're running 25 volts. That's a little better. And Y1, Y2, they're both calling. Solenoid does work. I've unplugged it. Replugged it. Unplugged the compressor. Replugged it. It's unloading. So we've got something going on here with the way it feeds. We're going to go ahead and check the RPM of this. It's reflective tape. Tagnometer will pick it up. Going through the instructions here. I haven't done a lot with this particular model yet, but they say they want at least 1,700 and some odd rpms for high speed. That's for VFD. Just kicked on. Yes. Being the door band open. Going to change it a little bit. I'm running right around 782. So here's how it's laid out. Get your 67% and 100% capacity. So it comes out of the condenser. It goes straight to the TXV all the time. Sometimes it will go through the orifice when it's under full capacity. Then we got to make sure our airflow is correct, especially since the TXV has been changed. The stuff I was looking at earlier sounds like that was more to do with VFD. All right, so we just checked our amp draw on the motor. It's 8.8s are max. We're running like 4. The inside, I checked the airflow. Make sure all the registers are open. They are. There's a total of eight commercial registers. Each one of those are probably a 10 inch. So we are not moving near the air. We could be moving, which would also make sense of why we're freezing up. We're going to speed the pulley up. You can see how deep we are down in the groove there. So we're going to speed this thing up, get a little closer to where I think it should be at, and then kind of check things once we got it running. Once we know that it's not freezing up, then we'll check temperature drop, stuff like that. Okay, we did two full rotations. We still need to align the belt. I had a couple multiple corrections with it. Must be getting a glare off something. Once I held it in the right position, it looked like about 8.60s area. Still only pulling 4.7 after this. Which is different. That's odd. We just found this. That's going to cause some problems with the heat not working right. So we're going to have to fix that up. That's going to short out. Okay, we went ahead and taped it. The insulation's not missing. So this will keep it from opening up. I brought it on through that way. We aren't arcing anything and it's out here at least an inch and a half from anything. So it's not going to arc to it. All the wires are away from it. We're at least staying above 30 now. That's a good sign.  It's not too long ago. I had a peak out of my pressure.  Like took them into zero zero land and I don't know if it made it damage them. Because right now they're working fine. I'm going to go another turn yet on that fan and get that speed. I'd like to check static pressure and see where we're at on that. Jumping back over to this for a 6.60. We just found it off. We're not losing anything. I've smelled this a couple different times. It smells fine. I'm going to put the gauge on it. Make sure the PT chart matches up. It does. I'm just going to reuse it and add whatever we need to add to it and kind of go from there. Everything else is looking pretty good. Right now I pretty much got this disconnected. Got the wires back to the way they were. I think I'm going to go one more turn on my fan yet. So 5.8 is our highest leg on the motor which we had a room up to 8.8. Recheck the RPM. We're right about 900. The wiring. I cleaned it up. Got rid of some of this other stuff. Okay look at that. Our suction's up pretty decent too. A little bit worried here as to why I like our super heat. It's coming up. We'll let it run for a while. Let's put the cover on. Still got to get to this yet. Where are we at on that there? Came up some. Go ahead and let it run a little longer. It should be slowing down. Yeah look it's still closed. It's starting to slow down so we're boiling off for refrigerant. All right so we're right at 85 degrees. 85, 86 degrees. Right there, 85 degrees. So for the most part from a PT point of view, PT charge point of view, we're right in line. So I'm going to reuse it. I don't smell any burnt acid smell that you normally smell and see where we come in. Adam will slowly weigh it in to see where the side glass ends up being at. You see we went back down and it's kind of holding down there at that 800 mark and it's actually still going back down yet. We're going to dump a little bit of liquid into our suction liner to bring itself out of the vacuum. Then we'll remove the gauge. Won't take much. That's five ounces. And for those that are worried about it, the liquid's going to boil off. You can charge a system theoretically in the opposition liquid it's going to boil off. What happens when it shuts off on a normal procedure and it doesn't have a pump down, it's going to boil off. You're going to get possibly some liquid back but like I said we got the receiver and everything else there. But as soon as we get that up to there we'll go ahead and get that taken off. Which we are doing it on the vapor valve upside down. That's the bigger opening. It gives me more flow. It's a little faster than doing it the other way. So we're dumping some in right into the receiver. We are not dumping any more into the suction. The suction is around 19 pounds there. We're going to go ahead and get this thing installed again. That way we don't forget and burn anything up. Check our pump oil before we put it away. We're 54 forever. We're going to go ahead and change that oil. Let's go ahead and dump that back into there. It's completely empty. Cool. Got a little bit to it. Just about there. And look at that. Well and behold, it starts to drop. This is as I quit moving the gauge around. Right in the middle area. And there she goes the rest of the way down.  Got everything cleaned up. It's able to run that wire on the outside so it doesn't actually touch anything. Everything's tidied up there. Coils on. Let's go ahead and start this thing up. Look at that. It didn't explode. That's a good thing. Is that why we lost the compressor? Faulty low pressure switch. See that? That constant tune, tune, tune. That could take the compressor out. Now granted I did not have it tightened down yet because I'm still trying to find my socket thing. But that shouldn't have happened. We should be out of defrost. Whoa. Whoa. What's going on? Yeah well that's why it got destroyed. Let's just put it that way. We've got a total of three safety circuits here. We have the low pressure switch up there. High pressure switch there and high temperature switch here. They're all in series so pretty much pick whichever one you want to pick. I'm going to say possibly the low pressure switch because it's the one that's constantly opening and closing. So we're going to bypass that one first. That blue wire comes off of the power terminal there. It goes down and comes back. So if we were to just take power straight from up here to there, that will bypass that switch and we'll try that first. If it still does it, we'll jump out of it, get out of that one, head on to the next one. We've got our jumper from here to L1. Let's see what happens. What's the other pressure we're doing here? Oh it's not wrapping cycling. That's a good thing.  Obviously our cyclist is fairly empty. We've got about 13 pounds in there so far.  All right so we've got registers there, there, there and over there and we've got some central returns here. All of them have got really good airflow. This don't feel bad either. This is going into a pretty good size channel and then looks like it's ducked over that direction there. Right there is why that wire was looping back and forth so it's smoke alarm. Hopefully yeah it's hooked up because it's blinking. Yeah we're checking our drop across the coil here. Okay it looks to me like we're about 69 ish area. Let's see what we're getting here on this. It's pulling it right off the ceiling I think is a lot of what's going on here. We're running 49 degrees, 69, 49 that's 20 degree drop across that coil. So going as slow as it would have been going right there would definitely be it. We could probably even go one more turn faster because we're nowhere near it on our maximum after on everything else. We've got some excellent flow but I don't want to create too many issues for heating either though. All right so my total external static is 0.45 to 0.43. We're looking really really good. That's I can't complain on that a bit. I'm thinking we're good on that. I'm going to leave my fan speed alone. Our static on just the return though is a 0.281 or 0.16 on the supply so we're definitely hurting more on return than we are on the other but that could be from sharp bends and things like that but like I said the total we're not doing too horribly bad from what I'm seeing. Jumping back out to here so we've got 15 pounds 10 ounces in it so far. We're still not looking full yet which according to what I had on that chart it shouldn't be yet so we're still still kind of getting out in there yet trying to do 50 things at once. Yeah we're definitely not. All right taking a look at our super heat sub cooling stuff. We're running 10 and 10. I don't know if you can ask for much better now. We're still running at second stage. A little surprise at how low we're running on our discharge. I mean that seems a little low. Of course they can't do normal settings. They've got to do everything cockeyed and everything else because they think we're too stupid to be able to figure out things but I think this is way more confusing than anything else. Outdoor leaving temperature. Outdoor coil leaving temperature. So we're running about 89. I had to move it around a little bit to get a better view. So let's just say 90. 85, 90, 95, 100. So 85, 90. So here's 90. We should be running about 350ish. Okay we're running 283. That's not real good. 283 it seems like I said it seems like it's low. Let's look at this again here. So we're running 90 degrees. 85, 90. All that line pretty much straight down. It's about 3, 10, 20, 30, 330ish. Remove charge if below the curve. Okay we got the new switch mounted up there. Ran it through, wire tied, loop de-duped, nylogged. So I've got my analog gauge here. I got it pumped down at the valve. Open her up. I got her about 23 to 25 area. That's negative 8 to negative 10. See what comes on here. Had a long line set. Rather it got a little bit lower. I do not want to go into a negative. See it releases a little bit. It hasn't unloaded at the end there anyway which you know what it's holding pretty good there. I may just leave it alone. Running my vacuum. Scrolls do not like that. That heater is working. Boy oh boy. That bad dog is hot. Probably should have rotated that to put it across that part right there in a better contact. Now we're working on this one. So I've got both valves cranked down on it, pumped it down. There's no pressure in there.  So now we can remove this away from the the valve and then we'll go ahead and get that thing removed out of there. This one over here is working good. Got that back together. Need to get a cap yet for the high side yet. Everything's good to go here. I did tighten up the bolts on the compressor. We're staying solid on our sight glass. Got a little bit of flashing there but it's mainly because of how hot it is. I think the condenser is kind of dirty. It don't look like it but it is a little bit. We can do that when I come back for the condensate loop heater for the reach or the walk-in. Got everything together in a pile that we don't lose anything. This air conditioner I think that initial issue I had was a problem with my gauge. Yesterday I was working on one and for whatever reason I had five ounces to this walk-in cooler and my gauge when I finally put my high side on because they they didn't make it so you could get it on it very easily. They didn't have a T on there. Picked it out and put zeros across here. Both low and high because it's still open. I think it may have screwed up my my gauges but right now everything seems to be fine. We're holding 32 which I've seen Carrier do that a lot. That's not a real surprise. Superheat still running 10. Sub-cooling running 10. Normal standards we're doing good there. Still calling for first and second stage. I called the guy that had done the work. The reason why that delay stuff was on there is because the old R22 system had it and that system had a lot of issues. So I think I'm still going to leave that off. We can always put it in later but I don't want it in there if I don't need it. I still got to tune in my head to span cycle control there yet but short of that he said he weighed in the refrigerant charge and it should be exactly where he left it at so we shouldn't have to screw with it at all. That's the most accurate way he's weighing it in. Now let's go ahead and get started with this thing. Unfortunately the only type I have is these brass ones. I hate that because it's paying the heiny to get it to stick. You got to use the high silver content. Use the special flux just not very friendly when it comes to brazing it in. I can't remember if I replaced this one already once. I'm not sure why this one's sticking but there is not a whole lot to these. Not much to it at all. So there could be something on the tip of it sticking. I'm not taking a chance. I'm just going to replace it. There really is nothing to these at all. It's up and down. Okay so what we've done is we've got to cut out. I tried heating it up. Now it's just a lost cause. I went ahead and built me a new piece here. That is a piece of rigid and I went ahead and heated it up with torch and nailed it with the hillmore tool. It just made it so much simpler. Everything has been cleaned. You got your in and outs correct. It's a similar metal deal going on here and they don't like to play well with each other. So they've got in and out going on. Look at that smooth lease situated right there. I'll admit my one that I hate the most and I have the most problem with is usually brass to copper. So let's see what we can do with it here. The brass takes a lot of heat on the backside. That's a bad spot. Clinging it up a little bit with the brush wheel makes it look a little better. It gives you the ability to kind of check into the joints a little bit better with your mirror and make sure it's all good to go. Kind of go ahead and put it together. Do a pressure test. I think I had to replace this once before because that's why I have these valves here. I was able to isolate it from the refrigerant charge and I can actually do a little bit of a pressure test here. Don't want to go too high. Don't want to be able to push the nitrogen into the refrigerant because you can contaminate the system and I have done it before. So that's a mistake that I've made once and try to never make again. So I kept everything up there on the piece of paper that was up there on the counter ledge, whatever you want to call it. So we got that there like that. This comes in behind it. Got that ring and that seal. All goes together like that and then we can tighten it down.  I do have a little nylog here. We'll just do that real quick and just get a little bit here on our touching surface. If we can get it to come out. There we go. There we go. A little bit of there, a little bit there, a little bit there. Good deal. Give it a little love, a little finger action there. So we opened it up. Everything here was sealed, pushed it back to here, pushed it this way, did a pressure test on it with the refrigerant and it's holding. I did have to go over this one again with the regular alloy because I didn't add any flux to that one because I wasn't planning on actually using the silver. The silver was a nice, it fed right through with that which I was kind of wondering how that would do. I've not really tried that too much. I brazed over top of crappy solder, soft solder and then tried over top of the you know the actual 45% stuff. So now I know.  Don't look like we've got anything. We've got a nice solid screen. It feels warm on both sides. That's a good sign. My glass is still solid. That's good. Looking good. We can always clean things up a little bit better when we come back. All right, I threw this one into a defrost because I didn't want to have the same issues going on with the other one.  Kick it out. We'll go ahead and set it for five o'clock. There we go. It's good to go. All right, so I put the pros on there because I want to make sure that the manifolds weren't acting up and I have pretty much exactly the same thing. So 360 and 90. Those are my high and low which is 108 and 26 degrees. You can see it starting to freeze up already which makes no sense because unless the TXP is trying to find itself that's the only thing I think it could be because right now you're increasing the head pressure which should bring up your suction. It should fall as soon. It may have just adjusted though. Look at that right there. It may have just adjusted hopefully because I'm like still leery of saying it's good to go until I'm positive and when I seen that jump like it did and it's probably what it did. It was steady head pressure. Head pressure changed then it must have had to counter the pressure on one side versus the other and it's literally freaking 530. I'm beyond ready to leave. I'd be 615, 630 by the time I get home. So we're gonna wrap this thing up guys. Hopefully you enjoyed watching it. I don't do everything perfect. I try to but you know that's that's what we have. We had a bad compressor there. We got that done. We had a bad solenoid here and we had poor airflow here and who knows we may have other issues now. So we'd have a good temperature drop. Superheats up cooling. All that was terrific. Pretty close to the charts which I don't trust them half the time anyway. But you can see it's starting to flip back even more. Shouldn't even call it flip back. It's starting to frost back even more. So it just makes no sense. Well that's that fan stopping. I can hear it playing his day. If you enjoyed the video and you want to see more like it, if you would please give it a thumbs up. Don't forget to subscribe. Check us out on Instagram and Facebook and until next time we will catch you on the next one later.