Dr. Clifton. Hello everybody. Good. Doc, you can call the order if you want. Oh, sure. We'll call. And we are, we're still to some other way than the other Dr. Dr. Levy, but I don't think we should be expecting him today. Yeah, I don't think we're expecting him today, so I am going to start the recording. Okay. We'll call the meeting to order, and I think someone has to second that, is that right? No, just go ahead. Oh, okay. We have to approve the minutes, and somebody has to second that. Right. Okay. Meg, Deely, she didn't receive those, so I think we're just sending those to her. Yeah, I just got them from Jim, thanks. Oh, sorry about that, Meg. No worries. I probably have an email in my inbox from a different bag, instead of why are these on my channel? I don't recognize the folks in the Ramon process, or what I presume to be the Ramon process. Sure. Why don't we take both first, and then Bryn will be able to tell you who's in that room. Okay. All right, I can do that. Dr. Clifton is here, Meg Delia, Jim Romanoff, all present, and we also have Bryn here, and it looks like Sharon James Pepper, and then Bryn, could you tell us who else is in the room? Sure. We have four members of the public, and we also have Melissa Anderson from DPS. Great, thank you. Oh, marvelous. We'll have some time for public commentary after. And then, Doctor, if you want to get approval for the minutes? Oh, sure. Can I get a week and one for the minutes? I'm someone. And I think Meg's still reviewed it. I'll make a motion to approve it. I reviewed it. Jim, I don't know if you've got a chance, or had any comments on it. You did, Jim. A second. A second. Okay. Those are approved. Do you want to proceed with the agenda, Dr. Clifton? All right, sure. Thank you so much. I think, let's see, I'm putting up the agenda now. I feel like we've really moved along beautifully here, and we probably can, you know, maybe the last meeting unless something comes up today. Oh, shoot. I just pulled up the minutes rather than the agenda. Let me see if I can get the agenda pulled up. Okay. So for today, we wanted to review maybe the, and potentially finalize the possession caregivers and homegrown and do some assigning tasks. And of course, public comment. So I wanted to get cooking then specifically on possession. And just as a review, we were talking at our past meeting about the possession issue being, you know, somewhat tied in with any possession issues that can come up from recreational in terms of amount that people are allowed to carry. But we also worried that in some cases with medicinal patients they would have, they would pick up a 90-day supply at a time in which case they might have to have the opportunity to have a higher level of possession. And then we also, of course, have to make room from medicinal patients who are using concentrates like RSOs or DABS or something. So I just wanted to make sure that the subcommittee felt comfortable with possession limits that were consistent with a 90-day supply recommendation either by the patient's pharmacist or doctor or a care provider. And have that be our subcommittee recommendation? I would not agree with that. I think that's putting more on us on some sort of health care professional to determine what the patient needs, which is more involvement than those of us who are here at the subcommittee have to date. I am still in support of aligning with adult use possession limits. I would agree. I think that the Synchromole Abversight Committee had recommended an increase to three ounces in a 30-day period, which really isn't exactly possession, but it was a purchase of three ounces of medical cannabis in a 30-day period. And then in terms of a move that said the same thing, to make sure that it is pegged to at least adult use so that medical patients are analyzed for less if they're carried too much, but potentially more. But I would agree that putting the illness on health care providers to decide that the amount won't be going a lot further than we are now. Okay. My concern is that a patient might need more than three ounces and might find themselves transporting more than three ounces if they go to purchase a 90-day supply at a time. And then if they have four ounces and they're using it medically, they could be in a sticky situation. That's where I'm worried about the alignment with recreational. Jim, what do you think about that? Or Megan, what do you think about that? I just am not sure how many patients, how many ounces the average patient is using and if we're only at three ounces, are we covering for patients who are using concentrates at higher amounts or like seizure patients, people that are using larger amounts? The current law has had two ounces for a 30-day period and concentrates are considered as their actual weight factory as that amount of medical cannabis. So if it's one gram of concentrate, it's only one gram of medical cannabis. So that's really not an issue under the current laws. And we had proposed an increase to three ounces, which the prevailing opinion was that would cover, for the most part, most patients would cover all. I'm sure somebody will not be covered and be left out, but I think the risk to having a situation where medical providers would be pushed way beyond where they're at now to balance an increase to three ounces would be good, maybe not perfect, but better than putting it all in the hands of the medical providers. Oh, no, I was thinking about maybe some verbiage. Would it make sense to have verbiage of three ounces for an amount that could be overwritten by a medical provider or a treating pharmacist if the patient required a higher amount? So currently pharmacists are not involved in the program at all in that sense. So I think we can kind of just do away with that component. As far as a healthcare provider may be signing a waiver or saying a patient needs more, I think it's hard to really form an opinion based on that when we don't know what the adult possession limits will look like. Are people going to be able to walk into an adult use dispensary and purchase an ounce at a time as frequently as they would like? Or is that going to be limited to maybe three times a month? Whatever it may be, because we don't know that, I think it's difficult to say, okay, we want to align with the adult use possession limits, but here's a workaround for people who need more. Since we don't know what those limits are, I think three ounces could be a good minimum. Patients are allowed at least that, and then if adult use allows for more, then looking to those adult use recommendations. Ultimately, I think providers are not as involved with the actual purchasing process as much as they are just verifying. Okay, okay. I just don't want to put any firm on patients in a position where they're transporting some product and they're getting in trouble, getting pulled over and getting in trouble because they have a little bit more than they should have, especially for people who are high consumers. So I'm just trying to think of a way to make that as safe as possible for those medical patients. Okay. All right, then we can make a recommendation of three ounces as a possession, but then in the home we talked about really knowing inside the amount of possession in the home. But in terms of transporting back and forth a limit of three ounces. And then I think there's another thing you guys said we had thought about was caregivers. We were worried about how many people a caregiver should be allowed to see as a caregiver in different states have different recommendations. They are varying anywhere from one to 15. I feel like following in Vermont's, you know, sort of the way that I perceive the state of Vermont as being, you know, small farms and small businesses and neighbors helping neighbors. I think that a larger number of people for caregivers would probably be valuable and consistent with state goals and ideals. What is everybody else? Well, that's good. The advantage, lastly, in a caregiver situation, you know, we just need to be careful about the definitions. Right now, as it's defined, and I don't have it exactly, but as it's defined in the medical cannabis law, patients allow only one caregiver. And that we have tried to correct because it is unreasonable just from a practical point of view, you know, somebody needs 24 hours of care if they might have two caregivers. And both of those caregivers might be the ones that need to handle, carry, or pick up and purchase the medical cannabis. And right now, the patients are only allowed to sign one. But the issue in other states, and I'm afraid here, is often a little mixed up because the term caregiver is also used to apply to growers who are growing for patients. So I don't think that's necessarily a bad idea. Growers, small growers growing for patients, but calling them caregivers and including it under those, you know, laws just seems confusing and silly. So, you know, going forward, the recommendation from the oversight committee had been to increase the number of caregivers for patients because practically speaking was necessary, medically speaking, it might be. But also, the definition has been under some debate, but having an include growers probably would not be the direction. I would agree. I think when you start going down that path where you have one person growing for a number of medical patients, it then introduces, okay, well, at what point should we be getting some lab testing done? Where are there kind of these safety elements that we have required at the dispensary that a small grower is growing for multiple patients? You know, why aren't they subject to that? And so I would agree that the definition does need to be reviewed and that it should be made clear kind of that separation as Jim was alluding to. And I definitely am not saying that small growers should definitely not be growing for patients. I agree with that. There's all issues of testing and what standards things are going to be done to, but it's really just a matter of separating language. So it's not confusing, you know, a grower would be a grower. Caregivers are taking care of somebody medically speaking. And they'll handle their marijuana in New York. So they need to be more than one. Okay, so grower might be somebody who is doing a, I mean, we would just define them as a small private grower and then a caregiver would be something more of like a coach that would help to assist. You know, that's what I believe the definition, the medical practitioners on our oversight committee, you know, have expressed their desire for caretakers, you know, to be defined in that, you know, more medically and health care accepted way of taking care of medical health care needs as an aide or a nurse might do and administering or carrying the medication might be necessary, more than one caregiver might be necessary for the patient. But the idea, you know, the main law keeps getting drawn up. People are enthusiastic about it and I would just say, you know, suggest addressing it and labeling it in a different way and under, you know, licensing for growers and a grower for one medication but not confused with the idea of a caregiver. So someone can end up, you know, without somebody to take care of it in another way. So really there's no reason to limit caregivers at all. I mean, if somebody wants to be a caregiver, why couldn't they take care of 15 people a day? I, you know, that's not for me to determine I'm not a professional in the area of caregivers but I think the question really is whether each caregiver, you know, is a person who can grow for a patient and I know that's an issue that people are eager to address perhaps through the term caregiver because individuals can grow at home so a caregiver should be able to do it at home for a patient as well but maybe they should become a grower and it's a different thing. Yeah, so I mean, do we want to differentiate caregivers from growers and then talk more about home grow and I guess, do we want to do that or do we want to talk about caregivers as small growers? I'm sorry, I don't interrupt. I'll let Jim answer and then go ahead. Well, I think that, you know, the way that we've talked about it would be oversight committee. We should be using the language of caregiver to reflect an aide or somebody taking care of a person and self-care needs and handling the medication might be necessary. Growing it for one person spreads it into a different area and I think that's what people keep bringing up with the main law or caregiver. It can be a grower and it's just confusing. So I would suggest, I think the idea of a grower being able to grow for a small group of patients or one patient is an appropriate idea. I just think it shouldn't be bound together with the term caregiver. So I would say yes, addressing separately, you know, under how licensing is done for growers so that they can grow for an individual. Yeah, so I understand that. So I think we're in agreement that we need to make a distinction between caregiver and grower. But what I don't understand is because there will be different tiers of cultivators and cultivator licenses. And one of the terms of art within the licensing will be small cultivator, right? That's not what you're discussing. Heroin will be enveloped under that. But also, there's a separate product safety committee and testing is going to be mandated for all those levels of licensing. Are you proposing a different tier of licensing for small growers that just serve medical patients? No, I think what I'm saying is you would include in those small cultivators the ability for them to grow for a medical patient with the appropriate testing and guidelines, but just as they would grow for another small client. And I don't think you need a different cultivator necessarily. I agree. A small cultivator can grow for whoever the consumer is, including the medical patients. I don't know if you need to make any distinction at all on that end, right? Well, right now, caretakers are allowed to grow for a patient. And I think the question is going to be as any individual is allowed to grow and I could grow for an adult in my house under the law, you know, to do the work. And so, you know, I think the question is is when we talk earlier about home grow, I'm supportive of the idea of patients growing their own medicine and being connected to it. And yet I believe it's very difficult a patient who has disability in many ways to be very unlikely to be able to handle the physical burden of growing for a gigantic seven-foot plants outdoors or, you know, big plants inside. And it is risky. They can die, all those things I've mentioned. But the idea of having to grow or grow a specific strain or a variety for you makes sense to me. And where it gets confusing is right now a caretaker can grow for a patient. And there's a question of the language of a patient only being allowed to have one caretaker. And if it were a medical caretaker and a healthcare caretaker, not a grower, you would not say that about somebody you wanted to take care of. You would say they might need two parents. You know, depending on their needs they might need round-the-clock caretakers. So I'm saying split it apart and a patient can specify another person to grow for them, hopefully a cultivator or an adult who's not the, you know, isn't already growing for themselves and has the legal right to grow. Is that clear? Go ahead, Megan, I'm sorry. My concern with kind of separating these definitions of caregivers that it, although there are definitely a number of caregivers who are as gemizolidated to the medical caregivers, there are also a number of caregivers who are a patient's spouse. So I am a little weary of completely changing that definition because I think for a lot of the patients and caregivers we see they want it to remain fairly simple, which is they designate their spouse a caregiver, their spouse can grow cannabis for them as a medical patient. So I think if we kind of get into tweaking this definition of a caregiver, we do run the risk of kind of taking away that simplicity for so many of the people who are using it just like that. And I do worry that if medical patients could go to a small craft grower and designate them as a grower that it's it's just diluting further the patient population that, you know, currently we've discussed all of these barriers to access to increase participation in the program. So I do worry, you know, we saw when home grow was added a couple years ago, we saw a drastic decline in the program. So I do worry that if we kind of expand the home grow options in that sense, you know, let a patient go to a small craft grower that we're only going to further dilute the program and then essentially be back to square one because we don't have enough support for the dispensaries. I'm worried about these patients that, you know, they just have the money and, you know, where dispensaries are really just not an option for them because of the much higher cost compared to doing your own home grow. I mean, I'm worried about I'm worried about any negative impacts on home grow because I feel like in the cases of so many people with disabilities, you know, I mean, medical medical bills are the number one reason for bankruptcy in this country. So a lot of these people are really struggling already and if we hamper home grow, you know, then we may take a patient who let's just say, you know, designated their wife. Their wife is only allowed to grow for one patient.  They've got two growth cycles and then that'll give them enough medicine but one of their plants gets a fungus, you know, then they don't have enough, you know, medicine and they don't really have an option of going and getting insurance-covered product from a dispensary or they don't have any for a dispensary, you know. From a disabled from a disabled patient point of view with limited resources I'm really worried about limitations on home grow. I just want to quickly add I don't disagree that a parent, a husband a wife should also be able to be a caretaker in that same way and I think what I'm, the intention of what I'm saying is to not have the term caretaker, you know, sort of diverted into really being about how many patients at first you can grow for you know, to be able to grow let's use that term and say they can grow for more people it's just confusing and people use it as a workaround and so I'm poor grower growing for a patient and I'm for more people, you know and I believe the oversight committee it has discussed this in a few ways for people to have a caretaker at least the term, not be as confused now that being said, I have to say I disagree with the premise on the home grow that it's necessarily cheaper or a better idea it's not, I do it here, we don't have two grow cycles, we have three quarters of a grow cycle and if you're like my house I don't have some in the backyard if I didn't work here I couldn't move the plants on expensive wheels all day long to get enough sun to grow enough product that I agree with you that we have to support and preserve home grow as an option but it is more realistic to think that then I understand the next point of view about having growers who is providing the medical product but that makes more sense to me than thinking that somebody with a disability will, I know, or many of them using medical cannabis would have a difficult time moving the plants without handling it it's just not, I don't think realistic I would agree I have to say that I don't necessarily feel that the home grow option is automatically the less expensive I also think if you want prices of the dispensaries to decrease they're just simply needs to be more participation in the program and I think it's the dispensaries hope that when adult use rolls out and they can purchase from small craft growers they'll have a broader selection of products as well as lower prices because they are given that opportunity to also participate in adult use yeah correct me if I'm wrong some of this is academic right no one's saying take away or reduce the home grow option that's already there that is there yeah I don't deal with that just to bring this back to the focus what we need to take care of is the fact that it can't be one-on-one for caretakers and we can eliminate that as the recommendation correct I guess I would be curious to hear your thoughts on why it can't remain a one-on-one I think Jim expressed those I'll try and summarize it unless Jim you want to well I'm not sure I'm not saying it can't be more what I'm concerned about is the push to move in a direction as many great ideas as there are in Maine the idea of bargaining with a group of patients doesn't seem like the way the Vermont Medical Cannabis program has worked and doesn't contain the kind of controls that we would look for I don't think so that's what I'm trying to avoid caregiver being confused with lots of growers and there's a push to have multiple caregivers because you might need more than one person besides growing cannabis to take care of a patient for anything and so you just need to clean up that term if caregiver is just the term being used for a grower which is probably the designated grower or something maybe as they could be in the family they could be somebody else you know and then I think the question of the reverse of caregivers all of a sudden being people who can grow for five people and you know isn't a definition under the medical program but it's a cultivator definition and I wonder if there's an economy of scale if we have a concept that a caregiver can be a caregiver to 15 people and they're good at growing cannabis then they could have a home grow that could potentially aid in the support of 15 people rather than just one person that's where I'm trying to get to the same place Jim one minute there's someone's hand up in the room for about a minute or so now so we have Lindsay Wells here is in the room and she'd like to make a comment I was wondering what would happen to those caregivers of loved ones like the husband caring for his wife with cancer or the mother of the child with seizures because a lot of our caregivers I would say the vast majority 90% of them are not growing for a patient they're caring for their loved one it's almost like it's two different categories in a way not that I would want to prevent a mother or a spouse from growing but there's definitely two different concepts and I just haven't heard you talk about when you speak about caregivers about the mother with the infant with seizures or the husband with the wife going through chemo yeah I would agree with Lindsay here the majority of these caregivers are just as she described and so this notion that maybe one person could grow for 15 I think that's exactly what Jim was saying we don't want to go towards that it's a lot like the main model and we've both stated that we do not agree with that model for Vermont at current and that's Jim I don't know I agree with what you're saying and I agree and want to confirm I agree with what Lindsay's saying but you know that as I corrected myself before a caregiver or a spouse or a child epilepsy or cancer or something but the notion of caregiver or growers shouldn't get in the way of that those are the people taking care of their loved ones and might they be the person that's the grower? Yes but that doesn't mean we need to define a person who's a caregiver and a professional they might be a grower too and I think their desire is to say well I can grow for five people in the same way I can take care of five people but that gets under cultivation and we should just leave it cultivation licensing take care of that perhaps for the sake of simplicity we leave the caregiver definition as is and add in an additional caregiver an additional caregiver option but that is not to grow as Jim said maybe it's a medical caregiver maybe it's a second parent who's administered during the medication you know I think that's something that we would definitely feel comfortable with expanding how many patients a caregiver can grow for I don't think is the right route at least that's not what I'm hearing it should be reflected in the cultivator clause that they can grow for patients it just impedes what a caregiver needs Tom do you feel like like we haven't updated or write a recommendation from the subcommittee based on this discussion yeah that I guess I need a clarity on what Meg just said Meg you're not against expanding one on one caregivers as long as it's for medical professional purposes yeah because I think Jim is correct you know if you have 24-7 care it's unlikely that one person is doing that all the time and so I think it makes sense to add a second medical caregiver that might be a parent yeah it might be a parent it could be a child it could be anyone but to do so specifically as a caretaker and not somebody who can also grow for that patient I think one grower is fine okay yeah I understand now and I would just add to that that it would be great for it to be addressed under licensing how small growers it just and I understand Meg's point of view on that and I know what I'm saying is different it's just I don't think it should be addressed here yeah I agree okay okay I think that probably needs us to our final discussion about home grow and where we should where we should place that oh I'm sorry yeah Mary if I could backtrack on caregiving because Meg recommendations you also had um you also had a recommendation or suggestion that we discard with kind of verification or fingerprinting for caregivers um I think if there's only caregiver per patient then I don't see I think it's a just another barrier to the program to have that fingerprinting um also there's one in adult use I mean it just seems onerous that you don't fingerprint a lot of pharmacies so I don't see why you would think it's raining has just become such a commonplace thing it just you know and you juice every time you leave the country you end up having to put your palm on on the little stand for your fingerprints and for doctors you know to see patients in nursing homes or to see patients in hospitals you had to start getting fingerprinted you know as far back as 10 years so fingerprinting doesn't seem like a big deal to me or if you want to license in a new state all the states require your fingerprints but you know it's also well it's different and it's similar I guess I can see the point because you know I because I have a you know controlled substance license and so they want to be able to just have all the data that they would need if I were to be prescribing inappropriately so I would think that that would be the concept behind getting fingerprints but if caregivers are different from you know growers and they're just handling the product you know I don't have I certainly don't have a problem when we need the fingerprinting issue I think we have to hand up again in the room for public comment so the caregivers the spouse the mother the sibling who's helping take care of their loved one I think there's going to be some issues with fingerprinting process here in Vermont because they're not going to be able to bill individuals through the Department of Public Safety I don't believe because they're billed out for the charge of running the to be able to give some information as well they're billed out for the cost of running the fingerprint supported background check and to set up everybody as a vendor in the system but if you were going to create a different category for these like small businesses that were going to be providing a service that may be that you guys would consider separately I think since we I'd correct me if I'm wrong Jim but I think without expanding the number of patients that a caregiver can care for and or grow for I don't see it I don't think it's reasonable to have your spouse or whoever may be your caretaker fingerprinted if it is just that definition that we currently have the one on one I think you know what you were saying Dr. Clifton that is absolutely an aspect of your profession that I think yes you may expect but when our caregivers come in and they're just really trying to be there for their loved one or whatever it may be that fingerprinting process can really seem daunting and we haven't had it up until last year so unless there are any issues without having it I don't see a reason to keep that I think it would be a great thing to remove I mean in addition to just the hassle and the fear and all of the negative stuff associated with getting fingerprinted it's just harder and harder to get you used to be able to get in the UPS stores and now a lot of them have stopped doing that you have to go to the police station and then the right police officer has to be available so I'm with you guys outside and avoid fingerprinting for caregivers that would be marvelous I think okay any other comment anything else I don't want to move this along too quickly okay how about home grow if people have had some time to think about what kind of restrictions we would like to place on home grow I would say the Lother's Act Committee had recommended an increased number of plants that's where we stand for home grow no restrictions the increase somebody is going to do it they definitely need to be able to have more plants to ensure success so you know I mean it varies across the country I pulled up that sheet that I created last week but that was more on possession rather than on home grow but I mean anywhere from you know three flowering and three to you know six flowering 12 in mature and unlimited seedlings and I would lean in that direction again Jim because of what you said you've got a three quarter three quarters of one season in Vermont coming from Michigan I understand you have to be like some kind of wizard to be able to have a successful out garden and does that seem reasonable for us in Vermont for home grows and I'm sure there are people also growing imagine it's a majority of people doing it but decreasing the number of plants I think the risk is is the attention of limitation of plants is to A. limit the amount that an individual is possessing whether they're a medical patient or not you know as chairman Petra pointed out last week there's no specific limitation of what you have in your home and in your house but I would argue if there's a medical patient who's going to process eight or 12 plants after they harvest you know that's a lot of work and just doing three or four plants is a lot of work so you know increasing the number of plants I would say it's got to be right now it should be double and it could be up to 12 but I don't see you know for one patient it's going to influence that much what they're spending is going to be because there's a unless you're running a professional operation which is what they're not doing there's just a but you can't it's just not that and you're not ending up with there's going to be plants there's going to be plants that if you're making it into an oil or all a lot of work so more the numbers you recommended again Mary? we're six mature 12 immature and unlimited seedlings and that would you know I mean for somebody who likes to grow I mean I don't grow any of my own food I don't can or any of that but I mean I love to cook for sure but for people you know for my cousins who love to grow they have massive gardens so I'm thinking that supporting those who do grow you know so that they don't get in again into some sort of restriction or some sort of issue with with legal you know that offering just a very reasonable and generous number of plants that have a duty of restrictions that would okay guys correct me if I'm wrong but what I didn't see in the adult use legislation was discussion of homegrown so I mean it's interesting there's no kind of guidance it's there already you know statutes have just passed the numbers are there and I don't believe that those are sunset in the newer laws so do you know the numbers from the the original I don't want to say exactly because I'll say it it's too mature too mature or too mature yeah I thought you guys were 3 and 3 or 2 and 2 but I didn't have it I might think you're too tired that's a good use for medical I believe it's too mature and 7 mature is that right Lyndy? it's 2 and 7 for patients too too mature 7 and mature and then Dr. Clifton you're saying 6 and 12 yeah okay I would say the only concern I have with that is that that's a pretty large jump and so I'm not sure where we could go to get this information but I don't know how comfortable the legislature would be with such an increase to just my 2 cents I don't know if anyone has thoughts on that Dr. are your numbers based on other states? yeah I was basing it on Maine and just looking across the country at what would be the most permissive and thinking that Maine is probably doing that and thinking about Vermont not only the limited duration that grows can be functional but also because of the terrain and you know like Jim was saying that you can't you know you've got the trees in the backyard and thin soil with rocky bases so I was just thinking about ways to make it and because of such a finicky plant because of the fungal issues and things we'll get more numbers to be able to see that from Connecticut and some other states as well great thank you and then Dr. I'm not sure what I had two other things that were contained within Maine's list and they're both more compliance issues but I think maybe you were talking about the buffer zones and doing away with that it's more in another subcommittee geographic location yeah so right now we have a 1,000 foot zone as we're calling it and that is measured as the crow flies so there have been concerns raised by patients in the past that really affects the access because it's very unlikely that we're going to be having medical dispensaries in like a city downtown where there are absolutely going to be schools nearby or places where children congregate and so my recommendation was that we just re-evaluate that distance maybe reduce it to 500 feet and clarify that it's walking versus at the crow flies yeah and certainly I don't think there's any debate that the method of measurement needs to be clarified and then we can talk about the difference between 500 and 1,000 I'll just tell you also that in the market structure committee there's discussion of a potential license limited sale with existing businesses and that's going to present some challenges with whatever buffer zone as well so that's going to be developed by other committees the other concern you brought up was the limitation on how many can be served currently which is three which again I imagine that's going to be modified through adult use and then we can peg it to whatever use one other question was that it was my understanding that the future medical oversight committee advisory panel was to be addressed and I'm not sure if that's a agenda I was going to bring that up as well I mean we're on a timeline of this cannabis control board the November deadline to notify the legislature the oversight committee's goal has been by the beginning of October to deliver the recommendation to the cannabis control board and I would understand that it would go through this committee we are next Wednesday and we'll have a public comment period after that there are a few areas left that board members are still talking about but this committee would be able to look at and begin to discuss those recommendations next week and then wait until the public comment is also incorporated at some point in October to make a final consideration early in October and pass it to I would imagine Bryn to the cannabis control board to consider and the entire advisory board any preview Jim, are there a couple items on the board? some active debate among the board members as to who's going to sit on the board but I would say that the recommendations are leaning towards it being very patient and caregiver centric you know with the majority of the seats being going to patients, caregivers and then a smaller amount to medical healthcare practitioners whether it's a doctor or naturopath there's practitioner boards there's debate right now about including a cultivator on the oversight committee that's split right now discussions over and the questions being you know I think a lot of the board members feel it's really appropriate the cultivator being the medicine grower in this case at this point in the growth in life processing of medical programs all over the country the cultivator is the person most in touch with the medicine so there's a lot of debate and that hasn't fully decided yet and that is where we're headed perhaps also including some administrative temporary board membership perhaps public safety as they pass things over to mechanical control board but that will be discussed next Wednesday so that's where we're at I can share during this next week the draft document that we're working with for you all to consider and take a look at and we should be finished up with it I would say within 10 days Thanks that would be great and I do want to make sure we get some ample time for public comment but I just want to remind everyone again one of the priorities that I had when we were starting was to ensure what we discussed was forming that kind of baseline layer for products in each of the retail and I think we're going to start to reach out to some of the dispensaries if we could continue along and maybe even have one of them at one of these meetings so we can develop that you know that's going to be part of our recommendation of the board okay so I do want to make sure the folks in the room if there's any other public comment Dr. Clifton do you have any any other closing no I was just thinking I was actually thinking about how politicized mammograms have become and how mammograms are covered by every insurance company because breast cancer is such a highly political thing and I wonder if we should just put some comment in here that insurance company should be required to pay for medicinal cannabis or that we would strongly encourage them to do so in the state of Vermont and just you know start to open that discussion with insurance companies people who are relying on it for the medicine and if we have people who can't home grow and then they find themselves you know really trapped I think that would be really great to put in here somehow or in a separate memo but yeah that's something we can definitely discuss next next meeting Brinus does anyone have public comments yep we do have a couple of people who'd like to give a public comment you know here from Meg is what's best for her profit dispensary I hear very little talk about what is best for the patients I hear this criticism of the main program but in the meantime I wonder how are main patients being cared for I'm going to guess pretty well and if a caregiver means switching the definition of a caregiver to a parent or guardian so what does that mean for the patient it feels like it's all being so the patient is forced to go to the dispensary to get their product and that's just not what's best for the patients and also the Marama for Symptom Relief Oversight Committee that Jim is the chair of I've been sitting on those meetings for quite some time and it seems that they want to change the definition especially Amy Quingler and Dr. Joe seem to really want to change the definition of what a caregiver means to a parent or guardian because by the way the law is written there has to be a certain amount of seeds dedicated to caregivers so it seems convenient let's change the definition of caregiver and now now the growers don't get a seed it happens just like that the point of this whole medical program is to give the patients the best care possible but all it feels like is the point is just to prop up main dispensary the point is to give the highest quality product that's the whole point of this and growers have been here all along in many cases amazing product for their patients and I bet if you were to actually talk to many patients you would see all the time that they love the relationship with their personal grower because a dispensary is going to sell flower that is best for their bottom line not what's best for the patient just bottom line so that's kind of what I'm going to say right now about that but just my main point that growers need to have a seed here they're the ones who know about the plant there's all these boards I sit in it's amazing how little knowledge there is about the actual plant itself and what it's like to grow I think for that reason alone you need to have a grower on these boards but just to move on to a whole different subject there's also a crippling bait tax in the state of Vermont it's 92% bait tax it started off as the intentions were great the intentions were to stop the problem with jewel nicotine products in high schools and I think everybody can agree that it's an awful problem and it needs to be solved but what the legislature did is use language that was so broad that it affects every single product that has the word bait and so there's literally products that are arguably the best the healthiest way to consume cannabis and many of these companies won't even sell to Vermont anymore the 92% tax essentially just filled the whole program and you know so again just bringing it back to patients because that's what the medical program is about I think you all agree with that I think it needs to come back to that and make that the point not just insulating our dispensary and its profits from from a more expansive medical program thank you do you mind identifying yourself? sorry my name is Adam Grose everyone calls me Tida, thank you thank you Adam thank you Adam for that input thank you I agree that especially in the subcommittee we have to stay super patient focused thank you we had another public comment yep Vermont Growers Association Vermont Cannabis Equity Coalition I'm also a state registered caregiver in our Vermont marijuana industry I have been since the first year it's been operational 2006 2007 thank you for this conversation I'm heartened to hear you guys address home grow and also possession limits I want to actually stop for a moment and bring up two points of clarity so our organization tracks some of the national trends across the in each state and I just want to say that the average national average for home grow the plant count is 6.5 to 7 so that's the average national across all of the states we've been fixed at two mature plans for about two decades now so just some context to keep you guys aware of that also a second point of clarity before I move on to my comment caregiver allowances heartened to hear you guys talk about that that's something that we support I appreciate you guys getting ahead of that the caregiver allowances that was stated have been identified as 1 through 15 that's not true there are a couple states that have unlimited caregiver allowances so please consider that why is one of them I just want to be clear and accurate with some of those points that you guys had raised earlier and I wanted to bring that up I do want to say you know just stepping back and reminding ourselves in tongue you just did this a moment ago about what we're doing here and the purpose of this subcommittee we're here to address the objectives that we're outlining where not just continuity of services and products and ensuring them to the current customer base or patient base but really addressing the other issues that are in the current medical program which are affordability and access affordability and access I cannot urge you guys enough to avoid bifurcating our medical program and its licensing that would further complicate this program these are unique sensitive individuals, Vermonters who are sick to engage this program it should not be without red tape or appropriate regulation but we should not be and I urge you strongly to avoid creating further layers of bureaucracy and licensing that an individual needs to navigate to provide medication to patients that is a game-stopper for those that wish to participate in this program we are urging and you guys will see this in our language a five patient allowance for each patient and an increase of 10 mature plans disregarding immature plans these numbers come from Maine and a couple other states that have similar plan counts and regulations in their medical program so we are asking you guys to adopt something that is already proven successful in other states and so thank you and I'm just leaving it at that I appreciate it can you repeat your name? I'm sorry my name is Jeffrey Pizzatella from the Vermonters Association and the Vermonters Equity Coalition thanks the Vermonters Association and the Vermonters Equity Coalition thank you great do we have any other no public comments no that's it okay thank you I know we're out of time I'm going to go ahead and lead you to adjourn unless anyone has anything else before Monday's meeting I can second that one okay thank you everyone thank you for the public comments


What's up everybody Jason here for jazzy's case brace calm This is a five-spot giveaway in the XR team random with this 2019 Panini contenders football one-pack hobby break number one So again guys you get a random team here. Just quick little pack Only six cards, but quick little pack break Then we're randomize the customer names that bought in again and top five get into the XR team random Which number two is the last one guys, and that's all we have to do to unlock the XR brakes So here's a dice roll. Let's do the break first round of mice because we're names teams one and a two three times one two three three times Niko down to Steven then we got three times one two three Three times three times Arizona Cardinals down the New Orleans Saints All right three times three times and again guys just a quick pack I mean, there's an opportunity at a potential huge hit here I mean obviously, you know there you can never rule that out, but more likely than not it might just be just a quick little pack with no hits, but the one thing is that I've hit monster hits out of these little pack breaks But you just never know Could be a crack dice of any one of these players here There we go. It doesn't look like much. Yeah, just the insert All right. Well, we tried but it's coming from a box. So I Think we're gonna have opportunities of course to get something All right. So here we go guys now Here we go top five guys get into the team random dice roll Four to four or two and a two four times. Here we go one two three four Four times four times top five are in Niko just missing out but you did grab like 10 spots or so. So you have a chance man. Good luck Stephen R. You're in Niko. You are in junior. You're in Niko in again and Robert Runkle congratulations So top five are in to the XR team random now and This was contenders So I'm gonna put Tenders one But again for the customer that didn't get in don't worry guys Because since this was a little filler break that was part of the promo you will have a chance to win Potentially some money back if we sell out the next filler plus flawless tomorrow, which I think it's very possible So we go to the promo list team random spots plus fillers are counted towards this promo So I'm gonna paste your guys's names from this break here. Like I said, this was a 2019 contenders football one pack RT number one So you guys will have that opportunity So there you go guys So again, appreciate you guys the next ones in the store at 31 you will sell out and break tomorrow most likely Appreciate you guys. Jasper's case breaks calm


So normal rain is typically a little bit acidic because of carbon dioxide in the atmosphere. So the carbon dioxide dissolves in the water in the atmosphere producing carbonic acid. Carbonic acid can then ionize to produce hydronium ions and carbonate ions. So the increase in concentration of hydronium ions reduces the pH and makes it slightly acidic. But this isn't what we're really talking about when we're talking about acid rain. So natural rain is normally between 6.5 and 5.6 pH and that's because of that carbonic acid. Below 5.6 you can't really add any more carbon dioxide into the water, it just doesn't go in. It's already saturated. So when we're talking about acid rain, we're talking about rain with a pH of less than 5.6 and that's produced mainly from the result of human activities releasing oxides of nitrogen and sulfur into the atmosphere. So we'll start by talking about nitrogen oxides. So they're produced wherever you have really high temperatures. You need really high temperature to break the triple bond between nitrogen and acid. So between the two nitrogen atoms is a very strong triple covalent bond. You need to break that in order to get the nitrogen to react with anything. So in a combustion engine you have the nitrogen reacting with oxygen to produce nitric oxide which is NO. That nitric oxide then further reacts with oxygen to produce nitrogen dioxide. Nitrogen dioxide is an acidic oxide and it reacts with water in the atmosphere to produce nitric acid and nitrous acid. So here we have nitrogen dioxide reacting with water producing nitric and nitrous acid. Because we've got these a weak acid and a strong acid dissolved in the rainwater that lowers the pH and makes it acidic. Very important if you're using these equations you should probably show the ionization and the production of hydronium ions. Oxides and sulfur are produced whenever you burn anything that contains sulfur in oxygen rich environments. Often coal is a good example. Coal contains a lot of sulfur. So when you heat up the sulfur it reacts with oxygen to produce sulfur dioxide and again sulfur dioxide reacts in the atmosphere with oxygen to produce sulfur trioxide. Both of those sulfur dioxide and sulfur trioxide will dissolve in atmospheric water and produce weak sulfurous acid for sulfur dioxide and strong sulfuric acid for sulfur trioxide. So you get these weak and strong acids dissolved in rainwater and that again reduces the pH. Again if you're going to use these equations it's a good idea to show that it's acid by showing the ionization and producing of hydronium ions. So you can get acid rain occurring naturally. Usually after volcanoes go off you get a lot of sulfur going to the atmosphere. So you get sulfur dioxide being produced and sulfur trioxide. You can also get it from aerobic decay of dead plants and animals. When they ionize in water you get the hydronium ion being produced and that reduces the pH like I said. The main places that we notice acid rain in North America and Europe not so much in Australia. Also in Asia too.


Hi, everyone. Happy Friday, Joe, for jaspyscasebrakes.com. Come at you, yeah, that's right, Oliver. 2020 Gold Rush Shoebox Collection Multisport Random Hit Break number four. As you know by now, what we're gonna do is we're gonna pop open the case first, which is right here, and then we're gonna type in all of the hits right there, randomize your names. Thank you to all these people right here. Randomize your names, randomize the hits, and then match you up, and hopefully we'll match you up with something that you like. All right, so let's pop that baby open here. Who are we got? Kind of peek at what might be inside here. What could it be? All right, we're gonna, I'm gonna try to slide out the cards first. All right, we're gonna lead off with a Ronde Barber one of one. Nice, from limited football. So let me type these hits in here. One of one plate autograph from limited NFL. All right, next is next is John Long, Magic Johnson, and Ron Boone. This is a 1980, 81. Oh, signed by him. Oh, there's the Johnson autograph right there. Couldn't see it for a second. Nice, that's an authentic autograph. Beckett 10, authentic autograph. You can kind of see it right right on his torso right there. That's pretty cool. That's a Magic Johnson autograph from 80, 81 tops. Nice, next one is Wayne Gretzky. Nice. All-Star Jersey, Wayne Gretzky. Nice. Gretzky, All-Star Relic. Looks like from 1999 in the game. Oh, and we've got 1994, Parkhurst Hallboy, old Chicago Blackhawk, Billy Ray. Billy Ray, the old coach. And that's an authentic auto right there. Next up is Juan Soto Rookie Signatures from Leaf Ultimate. 20 out of 25 on card. One more card, yes, we've got Mark Ingram. Mark Ingram autograph on a scorecard. That autograph graded a 10. Any other cards, is that a card? What's this? Oh, these are cool. I love these. These are the old Baseball Hall of Fame postcards. And this one's Chipper Jones. Larry Wayne Jones Jr. There's his auto right there. Nice. See, I love these postcard style. All right, you've got the Beckett sticker right there. And the card and the authentication. So that's H-O-F postcard autograph. Nice, that's a cool one. Sometimes you can find like real old school postcards with their autographs. So those are pretty neat. Is that it, Jersey? Silver and black Jersey? Jackson, number 34. Nice. There you go. There's his autograph right there. Go Jackson. There's the Beckett card and sticker. I'm assuming this is the, these are all, should be all be replica jerseys. Yeah, there's nothing on the back. They may have some numbers on the sleeves and stuff like that, but that's pretty cool. Bo Jackson autograph replica jersey. What else? Mini helmet. It's like Sam Darnell, right? There it is, white out ink. I like the color of this helmet. This is a cool looking helmet. There's the Beckett sticker right there. Nice Beckett card inside. I don't think we've seen any, well we have that Magic Johnson. That was some basketball right there. Right? Yeah, this is going to be too basketball heavy. Who do we have here? Do we know this person? I actually don't know this person. What? No, not T Higgins, but you got the letter right, T. It's Clemson, yeah. Yes, actually. How'd you get that? Oh, he's in your mat, okay. Travis Etienne autographed eight by 10. I didn't, is he, he's not in the league yet, right? You never got drafted? Oh, he's on Clemson now, okay. So maybe next year? All right, so there are your 10 items right here, ladies and gentlemen. So you got the Ronde Barber plate autograph, the Magic Johnson, the Gretzky, the Billy, the Juan, the Mark, the Chipper, the Bo, the Sam, and the Travis. All right, so there you go. 10 items right there. We'll put all the randomizer results in here. There are your names, here are their names. And let's roll it, let's randomize it. Five into three, eight times for each list. One, two, three, four, five, six, seven, and eighth and final time. After eight, we got Rick Serrano. Oh, two of them on top. One Richard, one Rick. Down to Stephen Kay, both the same. Five into three, eight times for the hits. Good luck, one, two, three, four, five, six, seven, and once more, right? Yep, five into three, eighth and final time. After eight times, we got Juan down to Travis. Now Stephen Kay wanted the magic. He didn't get the Magic Johnson, Stephen Kay, sorry. Rick Serrano gets that. You get the Travis Etienne. We'll see him in the NFL next year. It might be a hold on that. Rick with Juan Soto, Leaf, Ultimate Rookie, Signatures, and the Magic Johnson graded autograph. I think the autograph was a 10. Chris with the Mark Ingram autograph on that scorecard, BGS10, Ryan Kasin with the Billy Rie, I think. Maybe 1994, Parker's Tallboy autograph. Johnny with the Bo Jackson autograph replica jersey. Nick Stover gets the Sam Darnold Oliver, was just telling us in the chat that he has this card already in his collection and now he ends up with a second one. Sorry about that, Oliver. John McCall with the Chipper Jones Hall of Fame autograph postcard. Jose with the Ronde Barber one-of-one plate autograph from Limited Football. All aboard the Big Hit Express. Woo-hoo! And Stephen Kay, Last Ball Mojo, the Travis Etienne, eight by 10. You're welcome, Rick. So there you go. There's the Travis Etienne right here. Looks pretty dynamic. We want him to be a first round pick. There's the Sam Darnold. There's the Bo Jackson. There's Oliver adding this to your collection. There's the Magic Johnson auto in the middle, graded 10. The card's not graded, just the auto. There's the one-of-one. Nice on-plate autograph. The Ingram, the Soto, the Black Hawk, the old Black Hawk's coach, and the Chipper Jones right here. Right there. There you go. And there you have it, ladies and gentlemen. I'm Joe for jaspyscasebreaks.com. Thanks for breaking with us. Thanks for watching, and I'll see you next time for the next one. Bye-bye.


What's up everybody once again is Brandon man Sean and today I have a snippet for you. It's a snippet from an interview I conducted with a rapper by the name of Uncle Adams and what makes him so unique is the fact that he found this interesting niche that you never really would have expected a rapper to find and he's like a rapper motivational speaker at a target audience that you wouldn't even have thought of but that's not even what this video is about this clip right here is about the power of context and how it can transform your music from being nothing to an hit or uncontroversial to controversial but I'll dive deeper into that after the clip let's go. So actually for the first little while that video wasn't really that controversial but then some people started to kind of make fun of it and then it turned into a group of people and then one really big thing that happened was Anthony Fantano you know him? Yeah, he gave me a review. Really? He reviewed original it was not a good review it was not good it was like a 20 minute review but there's more to the story so anyway that that sent a ton of negative traffic over to my channel to my videos and I wasn't used to that man I was used to people like praising my stuff like you know until the all these people came over so it actually got really bad man I got I had like a lot of a lot of crazy trolling and impersonation and people are asking my fans and yeah anyway then there's videos about all this on the internet by the way and then Anthony Fantano and I we started talking about this and he invited me on his channel and we did a video together actually very similar to this how we're doing an interview right now. Really? And he told me about some of the crazy trolling he went through and stuff and the video is called burying the hatchet with Uncle Adams. Okay. And then now we follow each other on Twitter and yeah so it's interesting so that's it kind of basically it wasn't controversial at the start but like I said a piece of content can change all of a sudden it gets into some different hands or something and it gets on a different platform and it's been a crazy ride with that song I never thought it was gonna do all that. That's really important because the point of that just how we talk about how some songs or pieces of content can take off and go viral just because it happens to get discovered or more visibility the fact that it's song can literally change almost its impact due to the context of the error or the whatever platform that is on it's something that we don't talk about as much. A prime example is really when you look at some of the behavior that people get looked down upon these days in pop culture or or how or how they might talk to women or things like that right there was a certain error where it was so normal right and it was such a norm so we take some of the stuff from back then and then you bring it into this day and it's wow but back then yeah of course it doesn't mean necessarily what was right or wrong but just changing the context of when something's taking place or who's the person who puts on their platform in front of a different fan base all those types of things can literally change the impact in the trajectory of the song. And that's it for now and that's just a small snippet of a great interview I had with Uncle Adams you definitely want to check it out it's coming out soon when I finish I'll put it in the description below there will be a link there but I want to know your thoughts on just the video you saw at hand other than that be like this video go ahead like button if you like it might as well share it and if you're not subscribed you know what to do hit that subscribe


Welcome to our new X-10 YouTube channel and Happy New Year! 2020 was a doozy, huh? This is the first episode of Lifespan News on X-10's new YouTube channel and also our first episode overall. Science and advocacy episodes as well as others will follow soon. Our next X-10 episode will be on the topic of chromatin remodeling and it will be published on January 7th, 2021 at noon Eastern time. While 2020 wasn't especially unique and challenging year, 2020 also brought us a lot of exciting longevity scientific advancements. So let's start off 2021 in our new X-10 YouTube channel with a recap of the most exciting stories from Lifespan News in 2020. Welcome to Lifespan News on X-10, your source for longevity science updates. I'm your host, Brent Nally. 2020 brought many new longevity-focused initiatives that show how the subject of healthy longevity is growing in popularity, not just amongst the general public, but also institutions. The World Health Organization launched a new data portal to monitor the health and well-being of people over 60. While the portal doesn't focus on regenerative medicine against aging, it helps draw attention to the problem of aging and it can be very useful to policymakers to foster initiatives aimed at supporting better health as we age. If the World Health Organization doesn't yet seem to know about aging as a malleable process, then the European Longevity Initiative launched by biologists and philosopher Attila Cordis may help change that. The European Longevity Initiative aims at bringing together EU citizens and residents to advocate for healthy longevity and bring this issue to the attention of lawmakers. We encourage you to subscribe to our new X-10 YouTube channel to help us solve the human aging problem. Once you're subscribed, be sure to click the notification bell and select all notifications to ensure you don't miss any videos. Now, back to the news. 2020 also brought us a new scientific journal focused specifically on aging and gerontological science. The Lancet Healthy Longevity was launched in 2020. For years now, there has been no shortage of the growing interest of the scientific community for this field. And by the way, Nature Aging, a spin-off of the popular journal Nature, focused on aging research will launch officially in January 2021, although articles are already available on its website. Several companies and research centers received substantial funding for aging research in 2020. As an example, a $5 million grant by the National Institute of Aging in the U.S. will be used to establish the San Diego Nathan Shock Center. This new center will be studying cellular and tissue aging in humans, reaching out to medical practitioners to let them know about advancements in the field of aging is every bit as important as creating new institutes and financing research. And 2020 saw the launching of an initiative in that direction. The Longevity Medicine Course held by Deep Longevity, a spin-off of Enceliopo Medicine. I took this course and I thoroughly enjoyed it and I really appreciate the team putting it together. And I'm also very excited for the more advanced longevity medicine courses that are coming soon. So if you would like to learn more about biojarentology, the hallmarks of aging, and other longevity course content, then check out the description for links. Lifespan.io's annual Ending Age-related Diseases Conference took place on August 20th and 21st, 2020, virtually. Originally a real world event, our conference turned into a fully online event due to the ongoing COVID-19 pandemic. The conference featured many prominent experts in the field such as Judy Campisi, Steve Horvath, Arboretta Gray, and many more. Recordings of the events are publicly available on Lifespan's YouTube channel and website. COVID-19 has certainly been the dominant news item of 2020. COVID-19 has also raised awareness of issues around aging because aging is the foremost risk factor for morbidity and mortality of COVID-19. COVID-19 disproportionately affects the elderly probably because of inflammation. The aging immune system is an underappreciated driver of the increased risk of poor health in old people. This may serve as a wake-up call on the importance to target basic aging mechanisms in order to reduce the vulnerability of the age during epidemics and or pandemics. COVID-19 has also begun a discussion about the health of the elderly and our collective responsibility to keep people safe and healthy as they age. Many experts of the longevity community have spoken up about the clear connection between aging and COVID-19. If you'd like to learn more then we suggest you read the article linked in the description below. We hope that at the very least the COVID-19 pandemic has brought more awareness to aging research. Our next story from 2020 was mixed news from Unity Biotechnology which announced that the Sinalitic candidate UBX-0101 did not have a significant effect in a phase two clinical trial. However Unity Biotechnology also announced a phase one clinical trial of a new Sinalitic UBX-1325 which aims at clearing senescent cells that may be involved in the progression of diabetic macular edema, an eye disease that can develop in patients suffering from type 2 diabetes and can lead to blindness. For our next story a study has shown that resveratrol which is found in grapes, peanuts, cocoa, blueberries, raspberries, and cranberries might be beneficial for people suffering from heart failure. In a small three-month human trial participants who were given resveratrol had an improvement in their heart function along with increased exercise capacity and a reduction in inflammatory cytokines. These are promising results but there needs to be a larger-scale trial ideally one with a longer treatment and follow-up period. Reversing cellular age in mice restores vision. Researchers managed to restore vision and reverse cellular aging in eye tissue and mice using cellular reprogramming with the yamanaka factors. This increased the number of cells surviving optic nerve injury and produced a five-fold increase in optic nerve regrowth. The treatment also restored vision and aging mice and made their optic nerve cells behave similarly to those of young mice. Next UC San Francisco scientists discovered that just a few doses of an experimental drug called ISRIB can reverse cognitive aging in mice within days. Older mice given small doses of ISRIB performed as well on a maze task as younger mice and discontinued for three weeks after the treatment. A single dose of ISRIB was enough to make the neurons form connections and react as sensitively as those of younger mice. For our next story from 2020, selectivity of the blood-brain barrier changes with age. Researchers have discovered that the performance of the barrier changes with age becoming less selective. It's not yet clear if or how this will change the research and therapeutics landscape, but it could affect how we think about processes involved in age-related disease and this could also be relevant for the design and delivery of therapeutics. For our final recap story from 2020, a deep learning network known as AlphaFold outperformed other teams in a protein structure prediction challenge by a significant margin. In some cases, its predictions were indistinguishable from experimentally determined structures. This is important because form follows function. A protein does its job because of the way it's shaped and predicting the shape of a protein from its sequence has been challenging for decades. AlphaFold successfully predicted the structure of a bacterial protein that had eluded researchers for a long time. The general consensus is that AlphaFold will be a game changer for structural biology, which will have a huge impact on related fields like molecular biology. That's all the stories from our 2020 Lifespan News review. Thanks for watching on our new X10 YouTube channel. Our next X10 episode on this YouTube channel will focus on chromatin remodeling on January 7th, 2021, noon Eastern time. Before you go, there's a few quick, free, and simple things that you can do to help us solve the human aging problem. If you haven't already, then please like this video, share this video on your social media to let your network know about our new X10 YouTube channel. Which of these stories from 2020 excited you the most? And was there a story in here that we didn't include that you thought that we should? Please let us know what you think in the comments below. And finally, please make sure that you're subscribed with the bell turned to all notifications. We really appreciate it, and we look forward to seeing you in the next episode, at least as healthy as you are now.


Hi everybody, Joe for jaspyscasebrakes.com coming at you with a brand new release 2020 2021 Panini Hoops basketball five bucks Random team break number five and that's from a fresh case. And this is our last case ladies and gentlemen, so breaks five six seven and eight That's it So six is already on the site jaspyscasebrakes.com if you're watching live so go and get it No vet common ship aside from Luca LeBron, Yannis, Zion and John Coby's if any Obviously hits numbered cards will ship but just veteran commons won't ship those will be donated to charity big Thanks to these folks right here for getting into the action. All 30 teams are in let's roll it. Let's randomize it two and a five seven for names and teams one two and Seven and final time after seven we've got Eddie down to Anthony two and a five seven times for the teams one Two and seven and final time after seven we've got the Miami Heat down to the Dallas Mavericks All right, Eddie with the Miami Heat Ramon with the trailblazers Joe Parisi with the warriors Sean with the jazz Greg with the pistons Brian with the rockets EA with the clippers Sean with the Suns Brian with the Raptors Anthony with the Pacers. We've got Pacers bucks on right now Bucks up 60 to 37 about four minutes left in the First half EA with the bulls Alexander with the magic Eddie with the Knicks Austin with the Kings of Nicholas with the T wolves Robert with the Hawks Jonathan with the Celtics Robert with the Cavaliers and my Lakers Austin with the Wizards. You're a wizard Matthew with the Nets Robert with the Spurs Steve Nelson with the Bucks Ryan with the Grizz Tyler with the Sixers Anthony with the Pelicans Matthew with the Hornets nice Jarell with the Thunder Brennan with the Nuggets and Anthony with the Dallas Mavericks Let's sort this by Let's bring it all on one screen sort it by column B Let's box these up really quick Tyler Spalding has the Sixers up for trade All right, let me flip screens here for a second. Oh And don't forget here. I'll drop this into the chat, too Remember we're we all have to and this is me included with the kind of wrap our heads around a new draft class here and what the In real line our thoughts on to what the big teams are now So twin Timberwolves obviously had the number one pick Anthony Edwards Weisman number two were the Warriors number three Lamello ball Charlotte Hornets So on and so forth. So those are the main three guys plus, you know, OB top and Halliburton quickly So on and so forth so MBA draft classes in the chat if you're watching live. Okay, let's pop open this Case here and see which five boxes we're gonna do And this is our last case in the personal break side Instagram live at Jasper's breaks. They're all sold out, too crazy So thanks everybody so 2345 All right, so let's take five off of here Then let's take five off of there. So we got stacks of five one two three four So we're gonna select a die Like that one right there and we'll go one two three four if I roll a five or a six I'll just roll again and it's four one two three four So the far right column you can see the stack of boxes above my head these we will save for next time So let's just Put some slash marks here. I'm sure we'll run all of those all of these tonight They might get mixed up, but that's okay as long as you see those little slash marks on there You'll know they're from the same case All right, so there's the there's the boxes we're gonna do right here All right, so when we come back Here we'll flip flip back to this list really quick when we come back We're gonna see if there's any trades and then the break stick around be right back All right, welcome back Some trade chatter, but in the end no deals were done. It's all good. Let's see what happens here five box ran team five from a fresh case 2020 2021 panini hoops basketball. Thanks everyone for getting into the action We really appreciate it. We got pacers bucks bucks are up 66 to 50 on the pacers with just about Just under 25 seconds left in the first half They're cruising right now I realized when we were during the trade window that all of the holiday brothers are Are on not on the same court at the moment, but They're all together no family reunion Justin and Aaron holiday are on the uh On the pacers and drew holidays on the on the bucks I know there's some other basketball games going on here. What's going on elsewhere in the league? Looks like we've got The sixers up 64 42 on the Hornets that's a half Mavs hawks just started Almost at the end of the first quarter 23 21 Mavs And I think that's in we've got clippers calves later wizards heat nix bowls Rockets thunder. What's our next ESPN game? Oh sun's pelican. Oh, that should be fun Sun's pelicans are the next ESPN game Which we will watch Discuss together To the kumpo five and five from the field 14 points It's pretty good Does does Yanis onto the kumpo lays down does he develop That outside shot or just a credible Incredible jumper. I mean then he's unstoppable, right? I mean he's already kind of unstoppable Even if he can shoot decently Especially from if he gets a little bit of a three-point shot going If brook Lopez can learn how to shoot threes All right, so obviously these rookie cards We're going to set aside right there Inserts like this will ship obviously that's numbers that of course will show there's isaacoro isa Stewart You know second-year zions will ship right John Morantz to There's brook Lopez. Yeah, he learned how to shoot threes And oh nice rookie ink Tyrese Halliburton Nice, that's what we want to see austin with the kings. Look at that.  He he likes what he sees there He wish it was for him It's James Weissman Kira Lewis jr. Someone brought up the rookie of the year odds Um And I think Halliburton was at a pretty pretty good pretty good odds There's James Weissman for the golden state warriors. John. What's going on? I like what uh What precious chua has been doing too I watched him play the other night. It was pretty strong Separating those rookies there And here's a Tyrese Halliburton rookie card So the auto and a rookie card. I'm sure there'll be a number of these throughout the break I want to consider grading some of these too if he's great out nicely and if he ends up having a A rookie of the year caliber season I mean Sacramento's likely going to be in the playoffs, right? They should be in the playoffs Might be able to show out in the playoffs as well. There's Lamello Charlotte Matthew Shearer Trey Jones Emmanuel quickly I think has been playing some good basketball too New York Knicks Eddie Romero with the Knicks and we'll do a recap at the end too There's Anthony Edwards It's a deep bay there's Tyler Bay no relation at least none that I saw over some quick internet research Edwards of course number one overall pick going to the Timberwolves Nicholas the vsc in your Cole Anthony Killian Hayes Aaron Naismith And we got Elijah Hughes Hot signatures rookie And that is for the jazz Sean Maddock with the jazz and Goliath Was there Where was Elisha drafted? I was dropped a little bit higher than that. He's he's a 39th overall Oh, it was a pelicans pick from Washington via Milwaukee. And then that was eventually treated to Utah All right, so that was our first box. There's obi toppen with Eddie Romero Getting the Knicks player Good luck everybody So let's see what this where the standings are at after what we've played about Little over 20 games for most teams most teams have over 20 games Sixers are two games ahead of the Brooklyn Nets The Bucks are two and a half game behind behind the Sixers Celtic says a little It's a little crammed. It's still crammed in there. So early in the season only 20 some odd games in Sixers Nets Bucks Celtics Are the first four and then the next four seeds are the Pacers Hawks Cavs Hornets And we got Toronto Chicago even New York On the outside looking in I guess even the even the magic and the heat the heat are Are only seven and 13 They're gonna heat up at some point. I would imagine I have a rough that's a weird start for them Pistons are five and 16 wizards are four and 13. I'm not I don't know if they're gonna be really climbing up the the ranks, but But in the east anyone can still get a playoff spot Right now outside looking in raptors bowls nicks magic heat What would be hashtag good for the hobby would be the new york nicks getting a playoff spot I guess charlotte saying in that eighth seed would be nice too seeing lamella and the playoffs would be good increase his stock But after that, yeah, I would love to see the new york nicks Get an eighth seed, you know, we can see obi topping quickly And then last year's rj barrett In the playoffs doing work When's the last time the nicks have even been in the playoffs? How long has it been since the nicks have been in the playoffs? New york the city of new york would go nuts Is that a Hot signatures stef curry you really should not be expecting Autographs of this caliber out of hoops. They're very few and far between golden state warriors joe perisi Warriors come out to play. Yay. It's pretty nice I set that aside for picture time james weisman Also for the warriors nice one joe Steph curry auto james weisman Team saying the checklist has a lot of curry autos. Well, it's maybe the Sneaky good way to get some curry autos then So there's tyrese halliburton purple parallel I like that matches the little color match going on here matches the color of the team Kings again austin He was he was about to trade those kings Try to trade couldn't trade mojo Now they're quickly for the nicks eddy anthony edwards Are there anything edwards for nicholas and the teawolves and another warrior alan samali itch Hoopside autograph another one for joe the warriors box here No, no one no one's impressed by the stef curry autograph only team pros made any sort of comment Everyone's just like meh stef Whatever Are there six different couriers in this it I can't imagine. There's a very many though like quantity wise of those six No one likes stef curry autograph anymore Sorry about that dropping skyler maze there There's halliburton again. All right three boxes to go next box What about the west western con we looked at the eastern conference in the last box western conference We got the top four jazz clippers Lakers nuggets jazz clippers and lakers all with 16 wins Jazz has five losses clippers and lakers both are exactly the same 16 and 6 Drops off a little bit with the nuggets nuggets are 12 and uh 12 and 8 Then it's the sun so there's nuggets suns grizzlies blazers and rockets warriors on the outside looking in spurs as well kings thunder maves pelicans Timberwolves wouldn't be hashtag good for the hobby. I think uh Warriors getting into the playoffs with james weisman. That'd be hashtag good for the hobby Love to see the kings And like the seven or eight c that'd be good too and show off tyrese halliburton And increase the stock of like de erin fox That would be good Mavericks I think are They're stumbling a little bit eight and 13. That's not good I'm still only a few games outside of a playoff spot at the moment It's still very early in the season. We're only like 20 ish games in but The pelicans are seven and 12 I've heard rumors. How do you guys heard the rumors here, right? Pelicans are might actually be sellers if they don't really improve By whenever the deadline is this year So jj reddick may be on the move. Lonzo ball may be on the move Might not be a bad idea They just kind of recreate a team around around Zion There's lamello ball for charlotte. Matthew sheeran Well, mellow has been playing some good basketball. Maybe Alonzo mellow reunion could be interesting. I could do this quickly again And we've got daniel oturo hot signatures rookie Clippers that's going to go to ea and the clip show And the nix once again eddie romero logging in all these quick ways and Toppins and whatnot Timberwolves nicolas with the tea wolves burn All right, another obi toppen Tonya new york nix in the playoff. So it'd be a hashtag good for the hobby Then you veegess supposed to have some upside too I think he's been either injured or maybe coming off Covid lists or something like that, but It's for the for the washington wizards We'll save one of these austin all of those will go to you anyway We'll set one of those aside. It's supposed to be Israeli player It's got some pro experience already overseas So that that experience could definitely definitely help the the wizards We've got some players. I know they're not their record is only four and 13 That's the worst in basketball right now, but I think the idea is Those young players will finally click at some point with him and hachimura Elijah Hughes CJ behind him Oh that tatum was numbered And we've got an autograph here. All right, so we've got a couple things going on here. We've got jason richardson Nice for the warriors that's for joe We've got that numbered jason tatum 109 out of 199 For the Celtics jonathan Another hallowed Burton down here as well Nice two boxes to go Another five boxes in the store ladies and gentlemen check it out make it happen This is the last because this is the first five boxes of our final case Of hoops. We don't have any more after that. I know worries are cruising in this break from on All right. Good luck boys and girls next box looks like a couple spots picked up already in the next five boxes So let's keep shipping away at that. Let's see about a dozen orders coming in So we're two boxes away from being done maybe another 15 20 minutes or so we'll be we'll be done with this break So keep your orders coming so I can go through a bunch of orders and see what We can do right after this break. Do the bucks reach the final of this here? I mean that's that's the goal every year for every team, right? But the buck specifically with a player of yannis's caliber Good for the hobby Okay, thank you list There he is right here I mean at some point we've got to we've got to expect him to get to the finals, but what do the What do they need to do to get over the hump is drew holiday enough The hashtag good for the hobby And good for the game to see yannis in the NBA finals And we got jade and mcdaniels is your autograph your rookie inca auto for the timberwolves nicholas We've got another tyrese halliburton out here And all of these rookies are worth Especially the ones that You're more familiar with definitely looking up. I'm sure they have some great value Even some of the ones that are not so familiar still might be holding some secret good value Basketball market's pretty strong in general. Hey, there's the mella ball That'll be for matthew shira and charlotte At trade jones, there's another quickly Who's also pretty good nix eddie romero A couple of rookie cards right here anthony edwards and sedique bay Collin sexton number to 199. It's coal anthony josh green And obviously all rookies are gonna ship and i'm gonna try to catch as many of the sort of Bigger name rookies right here, but there's we also have a list of rookies that we're gonna We're gonna have top loaded everything is going to be at least sleeved rookie card wise There's a big list of players that will be Also top loaded by our sorting and shipping team before this all this goes out anthony edwards coal anthony avidja Danny devon vassal quickly, okoro wiseman ball top and So on and so forth. I'm gonna try to catch at least half of these Uh, okongu patrick williams pritchard sedique bay Theom maladon tyrese halliburton tyrese maxi So just in the interest of time, we can't do all of that here. We've got other breaks that we need to knock out But you don't want to try to catch as much of these guys as possible avidja goes to austin and these purple parallel of akongu will be for atlanta robert runkel like that design All right, i don't know why this looks so i think this looks cool All right, see you mic see you tomorrow rj barrett Calling sex and obviously these numbered cards will be top loaded as well We've got out of 99 de andre hunter And we've got we've got this dick right here dick barnett hoops ink autograph old school basketball player eddie romero with the nicks wiseman, of course goes to joe parisi and the golden state warriors All right final box ladies and gentlemen a little more room here Good luck All right, let's get an update on scores in our final box here in the third quarter four minutes Left in the third quarter sixers up 80 to 67 on the charlotte hornets We're watching the the spn game is pacers at bucks bucks up 88 61 was 626 left in the third quarter at halftime hawks Have the slight edge on the dallas mavericks 56 53 i was gonna say The hawks i feel like have to be on the cusp of Of breaking out already trey young i love john collins is solid too now they got they got some You know they got some other guys they got some guys like de andre hunter All right cam reddish they've got some draft picks some assets a conglue You know put all those guys together if they click at some point that could be a scary team you know Maybe a little trade Maybe a free agent addition Then all of a sudden in a weaker east Hawks could be a scary team like a team that you kind of don't want to face in the first round kind of team And maybe maybe beyond Trendsetter. Hello. I have a question. Yes. What is what is your question? How many spots are left in the Super Bowl mixture to try to win an additional spot? I think it says in the title doesn't it? I think I I think it says in the title check the title Aaron there's trey jones. There's quickly again anthony edwards All right anthony edwards goes to nicholas and the tea wolves and the quickly of course goes to The nicks eddie. We were looking at rookie of the year odds This guy actually had some I think some decent value on the on the money line there Enough to maybe put coffee money on there breakfast money Oh, there he is rookie ink Immanuel quickly Eddie Romero with the new york nicks. I've been looking pretty good That's a numbered Tyrese Halliburton And that is one That's 66 out of 199 Nice one, Austin Uh, Samuel wants that uh that quickly autograph eddie if you're in the chat I think I was watching quickly Whatever game he was playing a couple nights ago. Maybe sunday or monday night And I was just kind of half watching that game And how the corner on my eye See someone Slashing making plays shooting shots. I was like, oh look at that that rj barrett out there No, it turned out to be quickly. I was like, oh quickly interesting It's only half watching. I was like, I started paying attention a little bit more. I looked pretty good Tyler Spaulding will pay even more for that quickly autograph There's eddie No way he says he's like, that's mine boys No, thanks. Yeah, I mean He's got a If he can get close if he wins rookie of the year, I guess he's got a shot The value of that would definitely go up another Tyrese Halliburton And another Lamello ball right here too There's Lamello for charlotte mattheshira Another Tyrese Halliburton for the king's austin we've got Udoka as a boogie Nine out of 15. I think that's the best. I mean there he is again. It's the best I'm gonna do with that That's for utah And there's isaac bonga Hot signatures for the wizards austin With washington dc the district VIP with kawaii Leonard a couple other players right here And the out of 10 For the jazz shon matthek with this one and there you have it boys and girls that's five box random team break number five From jaskiescasebreaks.com number six is in the store The next five boxes Be sure to get in on it Because that is the last case we're working on the last case right now that we have in the shop Will we get more we're gonna try But will it be at the same friendly price point that is that at now? I hope so, but I wouldn't hold my breath generally when we re-up on these cases And personals went through a ton of cases too when we re-up on these cases are generally a little bit If the price has gone up, it would be a little bit higher Maybe it hasn't I don't know we'll find out nice. Halliburton autograph And of course the step curry autograph that no one reacted to I thought it was cool though There you have it ladies and gentlemen. I'm joe for jaskiescasebreaks.com five box ram team five in the books I'll see you next time for the next one. Bye. Bye


There's a right way and a wrong way to cut wedges for your wedge tenons. Hola woodworkers, Paul Carlson here, small workshop guy. When it comes to doing wedge tenons and spiking them with your wedges, there's a wrong way to cut them and I experienced that. So what I did was I ended up cutting my wedges cross grain and that's wrong. Now the right way to do it is to go down grain, in other words have your grain running from the tip to the end of your wedge. And so it's running lengthwise here. My son and I were gluing together my samurai carpenter workbench and we got to the point where everything was glued and clamped and on really tight and then we were going to drive the wedges into our split tenons. Well, because I had cut them the wrong way, they basically shattered. In other words, they wouldn't drive in far enough. They would just simply break along the grain. And so we were not able to, as you can see, take this bottom one here, big gap here because this has been cut off. But I had a wider wedge here that I couldn't drive down in because it kept breaking off. So I just decided to forget about it and I would do some sort of repair. Let me see if I can demonstrate that. So here's the wedge that's cross grain. Let's give her a little, so it breaks right on the grain. This will break as well, but I don't think if there's, if you don't, if you've got the cut. Oh, it damaged my little temporary workbench. If you've got the cut down there and then it's got some place to go, then I don't think it'll break.  So here's an example of how bad it is. I could try to drive a chisel in there and then get a new wedge piece and try to drive that in and close that out. And that might work, but I've got a gap on this side as well. I've got a gap over here. So I don't like those. So what I'm doing is I'm going to take a Forstner bit and I'm going to drill out some waste area in each of these.  I'm going to create a long bar of this design where I've got the maple, walnut, maple, walnut, maple. And I'm going to have it be slightly bigger than that hole. This wouldn't be the way it is. This is one that I cut off. I'm going to have one that's oversized in all dimensions.  And then I'm going to glue that puppy in there. And that's the way I'm going to repair my problem. And the idea here is to still have the strength, but make it look like you didn't screw up. One of the biggest advantages of subscribing to the Small Workshop Guys channel is I'll make more mistakes than your average content creator. And as a result of my mistakes, I'll figure out what I did wrong and I'll share with my audience how I fixed it. So that's what good carpentry is or good woodworking is fixing your mistakes so that nobody knows there happened.  Here's where I am in the process. I have cleaned all these out with the Forstner bits and chisels and got them as square as I could and lined up. And they're larger now than they were before, but that's okay. And then I've laminated a bar of my piece that's going to go in there to make it look like it's a spiked tenon. Now it's all secured in there. It's all spiked. It's very stable. I've got quite a long tenon. So I'm not worried about the joint failing. So this is just going to be cosmetic. Now I cut it purposely oversized so that I could then get on the sander and just bring it down a little bit at a time, a little bit at a time until I finally get it to fit into that mortise just perfectly. And then I'm going to have it stick out a little bit and glue it in there. And then when the glue has set up, I'm going to cut it off.  One, two, three, four, five, six, and then six on the other side. I'm going to do all 12 of them the same way. So it's going to take a little bit of work. I didn't plan on it, but when you cut your wedges the wrong way, that's what you have to do. You've got to get in the penalty box and pay the price. I've moved my belt sander over here where it's convenient. I hooked up to the shop vac and away we go. So I've got it fitting nice and tight in there. What I'm going to now do is just go to the bandsaw and cut it off roughly a little half inch or so beyond that. And then glue it up and pound it in there nice and thick and then let it set up and then cut it off. And if you enjoy watching me make mistake after mistake and disclosing those to those of you who might make the same mistake down the road, then keep me on YouTube and you can only do that by helping me out with sharing my videos and giving me some comments. Small workshop guy, siding off.