your identity.   You are not supposed to be mingled up with these people. Give me that an Ezra folk. You're not supposed to be mingled. You're not supposed to be learning what they learned. Read it. Ezra chapter four verse two. Then they came to the Rubabell and the chief. I choose not to engage very often with Heap because they tend to be people that you really can't talk to that you can't speak to. Their arguments are incoherent. They are all over the place. They don't read scripture in context. I'll start with this passage. Go to that passage. Go to that passage. Everything that's positive that refers to Israel. They want to refer them to in this case to blacks or different other ethnic groups here in the Americas. But they never tend to want to also apply the negative things, the curses that God has also, or the punishments that God has also put on Israel. Recently I've given a video to describe how we can know that blacks are not the true Jews or Israel. I'll say that there are no such thing as blacks who are Jewish. That's not what I'm saying. The point is though that Israel by and large as a nation, and by the way the Bible says that Israel will never cease to be a nation before the Lord, but we're also told that God has given them a spirit of stupor, that there's a partial heartening. Not to mean that no Jews will come to Christ, but by and large ethnic Israel, the nation will not do so. And we can't find one group, one national group, one ethnic group that by and large is refusing to place their faith in Christ. Is it that blacks, wherever they are in the world, are they by and large refusing to place their faith in Christ? No. Is it any sort of people from Scandinavia, any other whites across the planet? No. Are there, is it Asians, maybe Chinese or Japanese? No. We can't find any other ethnic group on the planet that is by and large refusing to place their faith in Christ, except for the ones that we typically think of as Jews, the nation of Israel. But I'll put that to the side because they seem to not be able to handle that particular argument. And by the way, this is not for them to hear. It's not for them because in many cases they're not going to listen.  Well, here's one way that we can know that they're not. Jesus tells us that when the Holy Spirit comes in us upon us, what are we going to do? We are going to preach Christ. We're going to give a testimony of Christ and we're going to do so not to just one group, but to all people. Jesus states that if I be lifted up, I will draw all manner of men to me. And so that's not just one ethnic group. And then Jesus also tells his apostles in Acts one that when the Holy Spirit comes upon them, that he will be preached to by him, by them to not just the Jews in Jerusalem and Judea, but also to Samaria and as well as to the rest of the world that is including Gentiles. God has always had this design for non-Jews as well. He says so in John chapter 10 when he says that I have sheep of another flock. He's also stated in other passages, his desire to bring about other people. He says that I will make a people who are not my people, who are called not my people, to be my people, who are not loved to become my beloved, speaking of Gentiles. Now, the Hebrew Israelites, they reject this fact. They don't see this fact and obviously so because the scriptures don't matter to them unless they can be shown to make them look good. But what you don't see them, well, two things you don't see, you never see them went out by themselves preaching because that's what people who don't have a firm footing on the scriptures do. They'll find someone else to go with them and they have these little large packs they go in, but you rarely see if ever one of them speaking by themselves. But the one thing you really don't ever see them doing is preaching Christ to the lost. You don't see that and that's a good indication for us as believers to know that these are not people of God. These are not called of Christ. They do not have any interest in preaching Christ. They have the only interest in their flesh, in their ethnicity and truth be told they're not necessarily the most coherent when it comes to their arguments and they could not be Christian because if they were, the Spirit of God would compel them, the love of Christ would compel them to preach to other people even if they were, even if they were, which they're not, but even if they were the true Jews it would compel them to preach Christ to other people because the love of God would want them, would cause them to want to see others come to him. And so make no mistake about it, these are not believers. These are, this is a cult, these people are not of God no matter how loud they want to yell, no matter how much they want to talk about their ethnicity and so forth and how blacks who don't support them have sold their race out. We won't listen to that. What we'll listen to though is the report that God gives us the gospel because that is the power of God unto salvation to the Jew first and to the Greek, the Gentiles according to Paul who is a Jew, who is of Israelite, who's an actual Israelite, who stakes this in Romans one. And so my friends, when you hear this foolishness, this nonsense, do your very best to ignore them, keep it moving. They are not worth your time. As the Bible says, there are times where you should not cast your pearls before the swine. Amen.


Hi everyone, Sean with Jaspies, casebreaks.com here doing 2021 Panini Absolute Football 12 box casebreak random team number one. We're all card ship. This is on release day. It's a full case random team break guys. And we're giving away an early bird free spot. So the way this works, 32 spots, everyone gets a random team at NFL, the early bird spot. By one of the first 17 spots in the break, get entered to win. We'll take the first 17 spots bought, randomize them. Top name gets a free spot in the break as well. So here is that list of customers that bought in from Gale all the way down to the early bird spot that we're going to give away. Sean with last spot mojo there. 17 first 17 spots with the early bird spots. So there you go. There is that list. So we're going to copy that 17 into a randomizer or actually copy not cut. There's the full list of Corey back up to Gale with the first spot dice roll team on our name on top after three and a five eight times gets the extra spot. So good luck guys. Eighth and final time. It's Carl. Congratulations Carl. You just won yourself an early bird spot all from just buying into the break early eight times on the randomizer eight times on the dice and Carl with the early bird spot. There you go. So now we're going to copy this full list over to a new randomizer and we're going to randomize that with the full list of teams to see who gets what team for the break. So here's the list of teams from Washington back up to Arizona and the customers Carl with the early bird spot he just won back up to Gale with the first spot purchase dice roll to randomize both lists and pair those up three and a five eight times guys. Good luck. Eighth and final time from Andrew Borelli down to Chris Butler eight times on the teams. Eighth and final time from Washington. Down to the dolphins. There you go. So there is the randomizer guys. You can see eight times on the teams. Eight times on the customers. Eight times on the dice. There you go. So Andrew Borelli with Washington. Peter Borelli, Tennessee. Corey Shawlick with the Vikings. David Baker with the Rams. Shawn Matic Packers. Carl Martins and Panthers. Gale Abloh Bears. Joshua Chitwood Texan. Zachary Schmidt Cardinals. Jen Ozug Bengals. Steven Woodke with the Seahawks. Scott Grossman Steelers. Corey Shawlick Giant. Shawn Matic. Last spot mojo Jaguars. Come on Lawrence. Corey Shawlick Eagles. Andy Rask. Lions. Carl Martins and Saints. Shawn Matic Chargers. Corey Shawlick Bills 49ers. Anthony Veterino Broncos. Andrew Hennessey Falcons. Corey Shawlick Ravens Cowboys. Andrew Hennessey Chiefs. Carl Martins and Early Bird Spot Colts. Arthur King Patriots. Joshua Chitwood Buccaneers. Nathan Rossi Jets. Andrew Rask. Browns. Mark Rowell Raiders. And Chris Butler Dolphins. Trade window is open. So here's your opportunity to trade for the team you were hoping for. There is the full list for you guys. While you guys are doing that, is this that camera? Space camera. Panthers, Saints, and Colts are up for trade. You got it? So like it automatically goes on if I go to the other camera? Yeah, it's not on there. It's not saved anymore. So I do I need to save it on this one too? Click the no click the add button and then go to video capture device right yeah and then go to like add existing and then is there a top and then click okay no just put it over the no no leave it back up there where was that but put it over the dodges drag it to where it needs to be okay cool that way turn it on turn it off cool thanks man. Okay so Carl's got Panthers, Saints, and Colts up for trade. While you guys are contemplating any trades I'm gonna pop this case open so you can see this is a full case random team absolute football 2021. Carl's nobody else is here for trading with you. I'll give it another minute or so but I'll probably close it out and start ripping the boxes. This is a full case break so I'd like to give you a chance. Chris says he'll trade dolphins for Saints. So Chris all you have to do is if you and Carl come to an agreement I'll just have you confirm that that's the deal and then I'll process it. So Carl says good Chris just let me confirm that you're trading dolphins for Saints. So trade confirmed Chris Carl I'll give it another 20 seconds for trades if anybody else wants to get in but Saints dolphins trade. Scott says he'll take offers on Steelers if anybody's interested. I know that Carl also had the Panthers and the Colts up for trade Scott. What's up Oliver? Cleveland Detroit here okay well well you since there are a couple people here Andy Scott I'll give you guys chances I'm gonna start popping these open you can see these are all cut open on the top I'm just gonna start stacking pack stacking on these but I want to give you guys chances looking for Joe P he hasn't been in tonight. So Scott said he'll pass and that was on Steelers. Kings beat son on a buzzer beater uh-oh who shot who's the who is the shooter Oliver Harrison Barnes nice out of all of that team I'm surprised it was him I mean not that he's not good but it's just like last minute last second in Devin Booker's face too like who are you gonna give the ball I wouldn't think it would be him that's good okay guys another 15 seconds for trades if not we're gonna close it out with just the one trade Saints for dolphins Mark says somebody take the Raiders from him he's averaging 28 a point a game right now wow very surprising but good for him he was uh he was 1718 rookie class wasn't he Oliver or was he 16 1617 any any last minute opportunities for anybody for the Raiders Mark scroll up did you see any potential there Steelers Cleveland Detroit who did Carl have Panthers Colts is he 10 years at this point huh I'm surprised he was 1112 damn Mark says he'll take any of them guys if any of you guys want to try to trade for the Raiders it's your chance um so Mark since you are uh wanting to get out of there I'll give you another 20 seconds and then we'll close it out any last chance opportunities for the Raiders any deals 10 seconds left guys I knew he got a ring with the water I don't know why I thought he was he was younger than that it's crazy though okay by the time I'm ripping done within this pack uh Mark if it's no trade then we're gonna close it up I know I know it is okay trade window go once trade window go twice trade window go in three times trade window close there you go so I'm gonna print this out oh never mind I gotta process the trade um so there was one trade the Saints Carl Martinson is trading out of the Saints into the Dolphins Chris Butler trading out of the Dolphins into the Saints there you go good luck to both of you and then plenty of tried to trade couldn't trade mojo for the rest of you guys there you go so I've got five boxes open there we've got another seven over on the right that's understandable David it's understandable I don't like either of those teams either so it's like you and I share a brain here is that final list and it sounds like a NFL owner dramatic staying cranky also which is not good for him not a good luck but strangely enough Jerry Jones is his defender just sitting here sitting back and watching and listening reading about all of it and I love it wants to um we're out of this is a lot this is the only random team we actually have for cases we're sold out of the rest um the last case we've got up right now is for picker teams that's actually the last case we have for now so I'm assuming we'll probably hopefully get some more tomorrow maybe Friday maybe both days so maybe more opportunities then for more random teams but pick your team three and four which are in the store for absolute football are the last ones we have we've been very busy over on personals with these so for tonight that's all we got um and the next pick your team three which is from a fresh case so all case hit opportunities explosive the explosive or the kabooms um are in play so um and it's now in a team filler team random filler only eight spots eight teams available I'm excited since we're doing a full case here guaranteed knock on wood obviously on average to see the two case hits which is the explosive and the kaboom so I've only done that half case so far and there was neither in that half I should be able to see my first kaboom of the year and exclusive exclusive or the explosive sorry explosive is a new insert short print case hit that they're doing for absolute and it looks great similar to the kaboom last two boxes guys we'll go through all of our hits any of the ssp inserts David which one are you talking about the two I was just talking about or is there a different one that you're talking about but yeah so kabooms and the explosives yeah so remember there there's one of each in every case on average um we say so we've done a lot on personal tonight we've only done one full case so far here on case breaks this is the second full case and the third case we've got split between two pick your teams yeah so we've pulled multiple of those so far today um highlighted by and the cool thing is too guys even though it says there's one per case you can have multiple kabooms or multiple explosives or multiple you know of both in the same case for example over on instagram uh teddy had done some personal boxes earlier and hit both a kaboom and an explosive from the same case right so people were hesitant to buy the rest of the boxes somebody came in and bought them knowing that the other ones have been hit hit a tom brady gold kaboom out of 10 and a josh allen gold explosive out of 10 from the remaining boxes in the case that had already had a kaboom and an explosive fold so like I said you can get multiple of each in every case you got ron del more for the cardinals and zachary smith that is to 199 and another one for the chiefs it's cornell powell to 399 triple relic auto can't see the chiefs andrew hennessey greg newson to 50 for the browns and andy rask you got frank gore 97 out of 99 dual relic for the dolphins first on the board for the trade motor carl martinson and there's a points card so that'll replace an auto in this box it's 900 points the way points work is we will take all the points that we get in this break hopefully there's not more than this but if there are we'll take them all and combine them and randomize that to one person in the break at the end of the break so you said 900 points is going to one person at least reshaw bateman to 100 for the ravens and cordy shaleck and cable fairly to 250 for the titans peter berelli and terrell davis very nice dual actually wow it's a dual auto john elway terrell davis one out of five debor broncos anthony ventorino historic dual signatures one out of five that's a nice start and right behind it alvin kamara explosive one of our case hits there you go nice looking card like i said this is the new short print case hit that they've done for this year styled like the kaboom very cool and obviously our john elway terrell davis dual auto i mean there's not a single broncos fan in the world that doesn't love that like i said one out of five that'll do that's the first this is the first box looks like i have 11 boxes for this break guys let's keep it going windows closed couldn't even see the chat not a bad start at all no one yet i think they're gonna do it tomorrow tom brady bass buccaneers joshua chitwood and jacob eason very nice two color patches that is 10 out of 49 colts carl martinson and davanta smith triple relic auto to 249 philadelphia eagles cori shalik that is 21 out of 249 pete werner to 75 for the saints chris butler big ben rothelsberger 173 out of 199 for the pittsburgh steelers scott grossman you got rookie auto tray mckinney for the chargers to 199 shon mattock larry roundtree out of 50 also for the chargers and shon mattock and pat frayer moved to 250 for the steelers scott grossman you got quinney pay autograph to 75 for the colts carl martinson and by storm ron dell moore to 75 for the arizona cardinals and zachary smith alvin kimara for the saints and chris butler dual relic that's 37 out of 99 and jacob harris triple relic auto to 399 for the rams david baker you got odafe oway 4 out of 25 for the ravens and cori shalik we've got another set of points decayed metcalfe to 99 relic for the seahawks and steve woodka and it's another 900 points that's 1800 points at this point that'll be going to one person in the break vaughn miller to 100 for the broncos anthony ventorino and almond raw saint brown to 250 for the lions andy rask and we got another explosive already three boxes in two case hits tyreek hill gold auto six out of 10 for the chiefs andrew hennessy and the explosive is tom brady buccaneers joshua chitwood there you go let's see if we can continue this two explosive case hits one dual auto three boxes in and a gold auto to go with that please give us more explosives and kabooms tools of the trade cam acres i don't know why the redemption is not put around 65 out of 99 for the rams and david baker the redemption is a rookie premiere materials auto spectrum which i believe is out of 99 card 205 jamar chase very nice since daddy bangles and jen ozag with the jamar chase rookie premiere materials autograph spectrum there you go elijah veritucker to 100 for the jets and nathan rossie you got nico columns to 250 for the texans joshua chitwood and christian barremore autograph to 100 for the patriots arthur king 10 out of 10 lamar jackson stargazing another gold for the break that's for the ravens and kori shalik kurtis martin love that guy that is 30 out of 99 or 90 out of 99 for the patriots arthur king jamar jefferson rookie auto 11 out of 100 for the lions and andy rask calvin ridley to 75 for the falcons andrew hennessy so there's an explosive brady on ebay right now with 545 dollars and two and a half days left i guess that's good is that a base explosive wrecks since an ad for the jamar chase congrats i blew myself already got ink on me i it did you did mark i liked it i appreciated it you got an air raid erin rogers and i really like the numbering on this it's 41 out of 75 but they integrated it into the design to make it look like it's part of like the instrument panel so it's actually kind of hard to tell but i really appreciate that good job for me uh green bay packers shawmatic christ evans autograph eight out of 100 for the bangles jen ozak and kenneth gainwell to 75 for the eagles and kori shalik you've got a dual relic of deandre swift tj hawkinson to 199 for the detroit lions and andy rask there's a redemption quinnon williams to 50 for the jets uh that is nathan rossy diamie brown for washington andrew berelli to 250 and mica parson's great linebacker for the cowboys kori shalik 11 out of 50 jersey number two jake bailey unsung heroes that's the 35 for the new england patriots and arthur king that's cool rex nice so rex in the chat was saying that tom brady explosive we just pulled um there's one of those for sale right now on ebay with bidding at $545 and two days left non numbered base version of the explosive frady pretty pretty cool okay let's see who the redemption is rookie premier materials autos i think those are numbered but i don't think it's the other one was to 99 um this i think the base is to 399 so it's that triple relic auto card 219 it's cheterious tutu at well that's for the rams and david baker there you go david in six box here so we'll be halfway down you got greg nuesome to 250 for the browns and andy rask chubba hovered for the carolina panthers to 75 that is carl martinson jaylen waddle dual or introductions 34 out of 50 that's gonna go to the dolphins carl martinson trade mojo nick bosa for the 49ers and kori shalik dual relic nice two-color patch there 35 out of 99 and dwayne escridge for the seahawks jumbo relic auto 51 out of 99 uh cl seahawks is a steven woodka a sante samuel jr to 75 for the chargers and shon matik you got kyle trask there's another points card that's to 199 for the buccaneers and joshua chipwood this is 600 points so at this point we're up to 2400 points um just so you guys know points kind of translates to about roughly every 10 points is a dollar so 2400 points about 240 bucks right there so not too bad ramble cob to 100 for the texans and joshua chipwood so we don't like points but at the same point 2400 points 240 bucks that's the spot price to get in on this break so that's gonna go to one person in the break those points alone will cover your spot when you think of it like that not too bad but no more points big autos case hits please okay so that's the first half of the case six more boxes to go hopefully lots and lots of more big stuff too you got derrick car henry rugs dual relic for the raiders mark row that's to 199 urnis jones for the rams and david baker rookie out of the 199 christian mccaffrey to 75 for the carolina panthers carl martinson dual relic for the lions and andy rask to 199 in book for the saints trade mojo chris butler triple relic auto there you go chris congrats to 399 carlos boogie basham to 100 for the bills cori shellick tom brady base buccaneers joshua chipwood and trevor lorence to 250 for the jaguars and shawmatic terrace marshal to 60 for the carolina panthers and carl martinson and elijah morta 50 for the jets and nathan rossie trey serman for the 49ers and cori shellick that's to 199 and javante williams for the broncos anthony ventorino triple relic to 399 and auto uh jurid dokes to 75 for the dolphins and carl martinson and erin rogers aerate again for the packers and shawmatic that one's to 199 panacea well for the lions andy rask to 75 stud left tackle greg rusota 50 for the bills cori shellick and another trevor lorence to 250 for the jags again shawmatic and hunter henry patricks edition 1 out of 49 new england patricks arthur king and patrick mahomes 30 out of 75 for the chiefs and andrew hennessy i gotta go through orders mark but uh whatever sells out will do i mean we could easily do that tonight there's no reason we can't the uh it's in a team filler though mark so it's not sold out eight spots eight teams up for grabs and that pick a team three is from a fresh case also so same opportunities for case hits you got jaylin darted into 250 for the buccaneers and joshua chipwood and mike goalick that's two out of 25 for the eagles and cori shellick mac jones 28 out of 50 patricks arthur king and justin fields for the bears gale ablo that is to 199 seth williams for the broncos anthony ventorino to 100 rookie auto and another trevor lorence this one's eight out of 50 so you've got two out of 250 and one out of 50 now for shawmatic and the jags last spot mojo anthony schwarz for the browns that is andy rask to 199 and davis mills houston texans joshua chipwood to 399 triple relic jaylin hurts to 75 for the eagles cori shellick very nice so third trevor lorence already third numbered trevor lorence two out of 250 and one out of 50 now let's keep that going these are all been in the second half too is there a world where we can get a trevor lorence in the last six boxes in a row i want to live in that world three boxes left you got ron delmore to 75 for the cardinals zachary schvitt and another trevor lorence spoken into existence that's to 75 jaguar shawmatic again last spot mojo urnis jones to 75 for the rams david baker and marquise brown to 100 for the ravens and cori shellick ricky williams for the dolphins carl martinson to 49 and travis etienne i thought that was another trevor lorence to 399 triple relic auto jacksonville jaguar shawmatic last spot mojo judo smith shuster to 100 for the stealers scott grossman and asante samuel jr for my chargers to 250 shawmatic cooper cup tools of the trade triple relic auto to 49 for the rams david becker to or baker to close that one out four left and double header filler rec says let's get that closed out guys two boxes left we can run that back right now i know david they haven't done you well especially cooper cup i don't like the rams but that guy's really good and even i can appreciate him as much as i don't want to you know two boxes left you got a rod erin rodgers packers and shawmatic 46 out of 49 and jaylon camp for the jags shawmatic last spot mojo out of 50 rookie auto tj watt to 50 for the stealers scott grossman and justin fields for the bears gale ablo that's out of 250 rookie auto anthony schwarz for the browns andy rask that's out of 100 and a mac jones gold four out of 10 for the patriots and arthur king congrats arthur we had a higher numbered version of that i think it was out of 50 earlier yeah out of 50 now you got that out of 10 jay compare us to 199 for the rams david baker and kenneth gainwell for the eagles cori shellick triple relic auto to 399 and michael thomas to 100 for the saints and chris butler to finish it off one box left guys good luck oh really nice scott that's pretty cool we've got the out of 10 and out of 50 here i don't know if there's an out of five but we got one of those out of 10 it's not too bad and last box guys let's finish it off for something big kenny and wongwood are 250 for the vikings and cori shellick and eric stokes for the packers out of 100 uh green bay packers is sean matt javante williams to 25 for the broncos anthony venterino exactly jamar chase for the bangles and jan ozak well it's a redemption that's to 199 vaughn miller to 75 for the broncos anthony venterino alvin kimara for the saints and chris butler to 99 javante williams broncos anthony venterino rookie jersey auto to 99 and diva samuel to 100 for the 49ers and cori shellick we got one more auto which is that redemption to reveal and then we're gonna randomize that 2,400 points guys like i said roughly 10 points to the dollar 2,400 points 240 bucks so it's not a not a nothing randomizer there it's just free money i'll cover your spot price for the break and walk away with whatever you got in the break so our last hit our last redemption of the break signature rookies spectrum card 101 wow trevor lorence last spot mojo sean mattick jacksonville jaguars there you go sean congrats man um so cascade we had two of the uh two of the explosives at the very beginning of the break so i'm guessing that's why there was no kabooms because we had two other case hits typically it's one one kaboom one explosive but this one was just two kabooms or two uh explosives so 2400 points going to one person we're gonna take the teams and randomize them pop over here so let's reset this so there's the teams washington back up to arizona dice roll team on top after five and a two seven times good luck guys seventh and final time so seven times the randomizer seven times on the dice top team colts sorry carl we're right there but it's the green bay packers and sean mattick 2400 points going to you about 240 bucks like i said worth of uh of spots for the green bay packers congrats sean some nice nice break for you especially since you had the last spot mojo and got the jaguars three trevor lorenz numbered base cards including one out of 50 and two out of 250 and a trevor lorenz redemption autograph there you go so you can see all the cards uh all the points are in one thing so all three of them there 2400 points going to you and there you go guys uh do a little quick little recap for you the points obviously going to sean mattick the green bay packers there trevor lorenz our redemption at the very end signature rookie spectrum for the jaguars eric stokes to 100 for the packers uh javante williams to 99 for the uh the broncos mac jones out of 10 for the patreots anthony schwarz to 100 for the browns jayland camp to 50 for the jags uh canith gainwell to 399 for the eagles urnus jones to 75 for the rams travis etienne to 399 for the jags cooper cup to 49 for the rams mac jones out of 50 for the patreots uh davis mills to 399 for the texan seth williams to 100 for the broncos uh mike gollick to 25 for the eagles javante williams to 399 for the broncos penacea well to 75 for the lions hunter henry to 49 for the patreots in book to 399 for the saints urnus jones to 199 for the rams terris marshall to 60 for the panthers dwayne escridge to 99 for the uh seahawks chubba hovered to 75 for the panthers and tutu outwell for the rams redemption christ evans to 100 for the bangles michael parsons to 50 for the cowboys jamar chase for the bangles that should be on a 99 as well christian barremore to 100 for the uh patreots jamar jefferson to 100 for the lions that was jacob harris to 399 for the rams quitty pay to 75 for the colts tray bikini to 199 for the chargers davancesmith to 49 eagles cornell powell to 399 for the chiefs to finish how it started we got lamar jackson stargazing out of 10 for the ravens uh tyreek hill out of 10 for the chiefs tom brady explosive somebody said that uh one of these is already up on sale right now with two and a half days left at 545 bucks just the base tom brady explosive a dual auto john elway to rel davis one out of five and alvin comar explosive and there you go guys that was the break very very nice case i must say that was 2021 panini absolute football 12 box case break uh random team number one from jasper's case breaks dot com i'm shan jasper's case breaks dot com thanks for hanging out we'll see you next time


And then their state media where they have taken and everything but the kitchen sink approach against the presumptive VP nominee, including but not limited to sexist smears and more than one person not even bothering to get Kamala Harris his name right listen. Just tell Kamala Harris what to say and she will say that is the whole point of her name is pronounced comma like the punctuation mark look Kamala. Okay, seriously, I've heard every sort of that's how it is come on. Okay, well, but that's out of respect for somebody who's going to be on the national ticket not to her name right is actually it's kind of a disrespecting her by mispronouncing her name unintentionally so it begins you're not allowed to criticize Kamala Harris or Kamala Harris or whatever Joe Biden was attacked by Kamala Harris named 3 things that Kamala Harris sincerely believes. Names can be so hard to pronounce sometimes even the names of people who have been on the scene for years. Say it with me. Kamala Harris. Kamala you know I've always said it the correct way but now that you mention it I kind of like the sound of Kamala now we're going to get right into this episode but first give me just 30 seconds to tell you about this special offer from my Patriot supply when you see what's going on in our country right now there's plenty to be concerned about social unrest is making life very uncomfortable and it could quickly get worse here's what to do right now go to www.preparewithdronetech.com and start building your emergency food supply today. The experts at my Patriot supply are the only people I trust and use and right now you can save $100 off a full four week supply of delicious nutritious meals the whole family will love so go to www.preparewithdronetech.com and get ready right now. That's www.preparewithdronetech.com do it now. Another day another gaslighting extravaganza from the Biden campaign media you can almost feel the seething rage in LeMond's eyes he's so upset that as he calls it state media is quote attacking Kamala Harris yeah Don state media unlike CNN and the rest of the media that are extensions of the Democrat Party and have now signed on with the Biden campaign I've been telling you for years now the media's job is to promote and protect Democrats while attacking and discrediting their political opposition and that's what you're seeing right now the media has already started to circle their wagons around Kamala Harris and they're going to lash out in anybody who dares criticize or scrutinize her as a racist or sexist or whatever other label they can come up with CNN and the other networks are already setting up the narrative that criticism of Harris amounts to sexism and racism and Trump's political style is not so much to debate opponents as it is to troll them deploying playground insults and childish nicknames to paint a vivid picture in the public mind but in Kamala Harris he's got a complex and accomplished opponent that he can't really seem to pin down yet I watched your poll numbers go boom boom boom down to almost nothing and she left angry she left mad he also went back to his old playbook resorting to a familiar sexist gear for his new competitor calling the senator nasty trying to portray her is too far left for the country. Hillary Clinton was very blunt saying she feels that sexism was one of the contributors to her loss in 2016 do you worry about racism and sexism affecting this race with Kamala Harris on the ticket. Yes there will be those that employ racism and sexism look at Donald Trump yesterday. Calling her nasty he would have done that to any person that Joe Biden selected. The president's Twitter account rolled out their attack video accusing Kamala Harris of being part of the get this the radical left immediately after Joe Biden made his announcement and that apparently is all they have. There has been criticism already of Kamala Harris and many feel that it some of the remarks have been sexist should Senator Harris and their campaign respond to these kinds of attacks. The culture sort of prime to be racist it's time to be sexist. Well Donald Trump's racism been even bigger issue in this campaign moving forward. He has so often employed a racially incendiary language as well as sexist language that would even hide it.   That's not sexism we're even getting at that is thinly barely veiled racism. Susan Rice Gretchen Whitmer any of the finalists they were going to be getting a volley of sexist and in the case of Susan Rice certainly in Kamala Harris they were going to get a lot of racist attack. You got to love how they use people's inherent traits as a shield against criticism and a weapon against their political opposition. That's exactly what we have to look forward to for the next few months. Censored tweets shadow banned posts and absurd Facebook fact checks claiming sexism racism or some other ridiculous excuse to bury any kind of negative information about Kamala Harris. If China Biden or Comrade Kamala get elected we will truly witness state media. I'm guessing even more extremely than what we witnessed during the Obama administration. I still remember the nightly outrage and hand wringing from the media towards Bush over high gas prices go away overnight and turn into oh it's actually good to have high gas prices because it's good for the environment. You wouldn't think high gas and oil prices would be a blessing in disguise but they are as Victor Lopez found out they're causing a big jump in the number of jobs. We turn now to five things you should know about gas specifically why gas prices even at over four dollars a gallon can sometimes be a good thing. And we know that rising gas prices are forcing us to search for alternative fuels and more fuel-efficient cars. There are some other reasons to be optimistic about the high cost of gas here are just a few of them. How about fact checks? Where's the fact checks? They're constantly fact checking Trump even keeping this erroneous tally of 20,000 alleged Trump lies. But when do you ever see them doing this to a Democrat? Biden has been lying about Trump constantly but never gets fact checked. He tweeted out the dead horse of a lie about Trump calling neo-Nazis fine people and Twitter hasn't fact checked it. Or how about Kamala? She told a whopper during her press conference yesterday that the media hasn't fact checked that I can find. In fact, they're just repeating the lie in their tweets. They leave it up to YouTubers to fact check. It's hit America worse and other advanced nations. What's the evidence for that? I don't think that's true. I mean just based on here let me look it up here real quick death for a capita and we're going we haven't going up a little bit but not much just by a world. Here we go by country. All right so here let me bring this over here. So she claims this virus has impacted almost every country but there's a reason as had America worse than any other advanced nation. All right well okay well she gave herself a little wiggle room there but per capita as you can see here Belgium is at the top. United Kingdom comes in second which is an advanced nation so not the worst. Where's the fact check? No there there's no fact check. They're just repeating what she said. Peru, Spain, Italy. Okay I mean Italy and Spain are advanced nations right? Sweden, Chile and then here we come the USA. All right so my god they're just lying why they got to lie all the time if it's that bad for real.  If you want to support me in my mission of exposing these fanatical frauds for who they are please hit that like button share and subscribe. You might also subscribe to my other channel Drone Tech Media. You can also support this channel by supporting the sponsors that keep us going or if you want to send a donation you can do so on one of the platforms listed in the description or pinned comment. Thanks for watching. Keep coming back.


Here's what's new this month with Passport. I'm a really good detective. I always get to the truth. Let's see how this plays out. Shaped by land, but sustained by the connection to us. These are American horses. What's happening in the Arctic could really affect everyone. It is literally sinking. These and all your favorite shows are available with Passport on the PBS app. Download it today.


The importance of weekly leads, very well done. Don't be a small fish in the sea. That's right. Become a tuna, then a great wife. And in group, yeah, action. It is so hard to succeed in this business. If you got a weekly leader order, we talk to them. Oh yeah, my name is Greg Cook and I'm a Secure Age Mentor. I do our social media coordinating and I do creation for content, creating videos, pictures, memes, stuff like that. And the reason I do it is to help improve sales for you agents and better usage of our lead generation or exclusive content. Hey, I'm Rance with Secure Agent Mentor. I'm the guy that's usually talking to you guys on the phone. I handle the leads. I handle some marketing. My whole goal is to just help you guys help the agents really become more successful. So we're always trying to create the best ads we can to get the best leads you guys can get. We're also sharing a lot of stuff on our social media platforms. So I'm hoping that this year's gonna be a huge year and everyone gets better and everything that we do really pays off and helps agents take it to the next level.


questions to the last lecture, how to organize policy control, which in all sorts of systems is a very important part. All parts. If you have data, you have to have pre-work-discussing standards. Someone has to control it. What is it? I mean, I know that is not an easy job. In all databases, you have to problem what should be in it and what can... because it's somehow taken as a reverence. And the data, the policy control is very important. How do you do all that? That's true. And policy control and models depend on how they are generated. So we allocate our data based on the... based on some levels. So we call them gold, silver, bronze. So how this is characterized through experiments, and we have high confidence we allocate those parts and models accordingly. And sometimes we use predictions or computational tools, long quantifying parts. So we use some predictions and in that case we say this part is characterized or predicted by using a computational tool. And that foundation is also searchable. If your tool is using the resources that I showed, you can filter them. You can use the high quality one if you want to. That's the quality control we have at the moment. But what I can also say is that in Silicopa it's going really fast so we can write a program and integrate data. But the feedback on the experiment at the moment is the bottleneck. The characterization of parts is taking more time. I mean, by asking this question we also have the problem in general with mathematical software, for instance. There is now a huge connection in overall form. How do we... I mean, we have a reviewing system for theory and for papers but the problem is how do you do the software, for instance, which you need if you do provide the algorithm. I don't know if there are, of course, several approaches but we tend to... we always tend to write some unit tests that would handle the particular problem and make sure at least they are covered. Of course there will be things that we didn't cover and it's like continuous processing. I guess if I may rebound on the question. For example, in the beginning when you mentioned ontologies and you said that you're doing faceted queries and aggregation of queries thanks to Sparkle and the ontologies. Of course you're managing content from the other days and you're querying with ontologies but ontologies could be seen as content as well when they are both. So how do you manage the fact that your ontologies can evolve as well so the same query could provide different answers from ontology versus one to ontology versus two on the same databases which is basically the life cycle management of the ontology. Well, I guess if ontology is evolving I assume your knowledge space, your data is also evolving otherwise you wouldn't just introduce a term just for introducing. I assume you also tend to take integration. At some time the owners of the ontology are doing the evolution by themselves on their side so the data is not necessarily reflect the impact. In that case I guess the query is going to turn anything basically. That's my point. But maybe we can include this process by making these terms available to the computation tools and the ontology terms available. Actually we have been doing an equivalent system for the industrial site and wherever we release the query language we check that basically there is some sort of mathematical equivalences for some query primitives from version one to version two to version three so that at least we retrieve the same kind of answers and if we have like dramatic disruptions then we need to within the system or at least revise the content. It needs to be revised. Like a very quick comment on this I think so I'm also involved in the ASCII development a little bit those are the kind of problems that we would like to have actually right now on the synthetic raw edges side because the more basic problem is that most of the data obviously is not in the ASCII stack it's not actually there so it's very good problems but I would love to have those problems reading a paper where I don't even get the sequence. I understand that. Yes sir. I was not mean to make you for the entire session. I don't consider it as a sanction against my country. So, up and down to the first two questions is your query system and database stable against the errors and full questions? If I put on a query with a minor mistake so what level of errors would yield a senseless answer and which one still brings something reasonable and useful to work with? Okay, the queries there are lots of query types the one that I showed here using ontologies and that would force you to create a ontology term so using these approaches you can't make mistakes because you have to use an existing ontology tool such as protegeal oil What you saw was a mistake? I can't. Using these approaches would have to so maybe the next thing is to provide a computation database abstracting views of ontology Excuse me, did you test your system physically? Yes, I did. Great. Is it possible to see some reports on testing? Yes, I was showing a table of summaries with classification so that was my example but then I presented some additional complex questions about pathways how to operate a home function how to operate a specific pathway or how to operate a specific coding sequence how to operate a home function for example and you can easily write queries but I guess you have to be an expert ontology because you are not I know but our task is then to provide some computational tools which would abstract that ontology level and you just use some drop down boxes basically I think that's the next thing Is it possible to the question to the previous the first one presided? Is it? Yes, sure What you said about the microbiome what kind of diversity or natural dispersion of that letter is behind your presentation I mean dietary actually affects the biome and some other aspects as well so what is the natural diversity of the biomes you have studied and what is the standard deviation of your data so this is a very good question and an extremely complicated one the standard deviation of our data is extremely small for the simple reason that what we are doing right now is mice, they are fed with the same batch of the exact same food over and over again they came from the same facility so from mouse to mouse there is a very minimal deviation in the type of microbiome they have but this is not quite artificial but this is also not quite natural in one of my introductory slides there was something about the abundance of bacteria bacteria is theta-iota-micron you need to change that name and in sample microbiomes about 46% of humans are going to have theta and conversely 54% are not going to have it that doesn't mean they are not going to have bacteria they are just going to have another one so to an extent everything we propose right now are proof of concepts and what we envision in the longer term is some form of personalized medicine where maybe this exact strain would not be the way to go but we are trying to develop sets of tools that can be applied to microbes that can be used within natural microbiomes same as the phage I presented a single scaffold but I am not expecting that any real life application would exclusively use t7 life phages we would need a couple of different scaffolds for the simple reason that some diseases are caused by ground negative, some by ground positive and to my knowledge there is not a single phage which is capable of targeting both so at the very least we need a minimum of two scaffolds the same is true for all of those bacterial engineering systems that we envision in bacterias we do it in bacteria ethyna eutomycron because it is somewhat characterized and to start a project you need something which is not completely unknown but we are moving into experiments where we actually isolate bacteria from natural microbiomes and see to what extent we can transplant everything we've built so far into those birds that we know nothing of the 16S sequence excuse me very simple question for two human beings with drastically different immune status very strong and very weak what kind of difference do you expect in biome in brief in the most general terms I don't know how to answer that qualitatively very different so someone who has Crohn's disease will see its complement of enterobacteria say about from about 0.1% to something in the range of 5% an example so it can be pretty drastic that's the whole idea behind the implication of microbiome disease these biases is the whole idea and we're trying to find ways to adapt microbiome to a more healthy situation and yes it will need to be tested obviously but we are not there yet at all so do you know what is the stoichiometry for the repression with the Cas9 do you need a lot of RNA and a lot of Cas9 or a lot of both things because you have a repression but by default you have a fixed amount of Cas9 and a fixed amount of RNA so do you know whether you can modify the effect by playing with the relative amounts that you have of Cas9 and RNA yes it's possible the way it is implemented in those data experiments is that Cas9 D Cas9 itself isn't a IPTG induction and based on IPTG concentration we see a similar response like you would expect from any other IPTG you don't know how many molecules are involved in the process you have like 1 to 10 100, 1000 to 1 the target is just one promoter so how much of the other components you need to have a repression so Cas9 works at very low concentration I would not be capable of telling you how many molecules of D Cas9 you have in the cell but it is not the limiting factor usually the limiting factor is the guide RNA because it's a small RNA and it's pretty unstable so the problem is that you have to guide RNA to guide RNA it was also easy building the data that I showed, I kind of skipped through it but you could see very drastic differences in efficiency from a guide RNA to a guide RNA and some of them differ by only a few base pairs you take one and you take one which is a few base pairs downstream and they can be as much as a truthful difference even through so it can vary drastically but it's difficult to deconvolve what is the actual efficiency of binding of the multiple components from stability of the respective components some sort of a founding question about microbiome engineering sorry for that but it really comes up it is pretty clear to in my opinion at least perhaps am I wrong that the microbiome is a world of itself that not only has interactions with the host organism but also has lots of interactions among the different bacteria or microorganisms that live in the intestine from that point of view if for instance we would like to set up a microorganism that produces some more of a vitamin for the benefit of the host it is pretty clear that it will change the composition of the microbiome because it will have some bacteria which will be favored by the existence of this vitamin that they cannot make for instance and will benefit from it and in the end it is not even sure that the host organism actually will benefit from this probiotic bacteria engineer bacteria so that my question then would be what is the value what is the value working on one of these components so I got theta is the name for me to obtain any type of result a net output in a real situation without taking into account the whole the interactions with the other microorganisms either through modeling or directly empirically so theta-yotamicron repeat after me now to get to the actual question so the question is what is the importance and this is an excellent question what is the importance of the interrelations between the various members of the microbiome when you are trying to engineer it and the answer is uncharted the only thing we know is that I don't know of any paper which managed to link in any way two species together we know they interact that's all we know so at this point it's completely exploratory maybe we won't be able to do anything useful and maybe we will and that's the whole idea maybe we will just one more thing what we are targeting now are more really diseased microbiomes so we're not really trying to go into the tabolo mix of the microbiome and just delicately engineering out a given pathway while increasing the level of expression of another one we are more thinking of things like there is a bad bacterium we want it out and this should be feasible I mean we can do it we can do some extending the lab it's a question of efficiency after that I have a practical question so you are working with a strictly anaerobic bacterium bacteria is strictly anaerobic but you are using as reporter luciferase how do you combine this because luciferase obviously requires oxygen nanobook that's the whole difference nanobook was designed for thermal or strategy to be active under anaerobic conditions so it's all in the reporter and I have no idea what they did but nanobook is perfectly functional under anaerobic conditions without oxygen well depending on the assays there may or may not be oxygen and here I would need Mark who actually did the measurements have a clear answer so we have made measurements where we take this tool and we do it in a test tube and here there's plenty of oxygen but he's also made in situ luciferase measurements and those I am not sure how we perform but what I am sure of is that nanobook works even under anaerobic conditions they first tried with various members of the fluorescent proteins none of them ever worked because of that anaerobic condition problem the other thing I would like to add is that although bacteria is strictly anaerobic it is oxygen tolerant so you can actually grow it anaerobically take it to your desk and it will not die it will stop growing but it will not die so there are a lot of things that you can still measure aerobically although you have grown everything anaerobically I am just curious you have a microbiome and you have these bacterial phages are they also in your gut they should be so yeah they are probably 10 times more phages in your gut than bacteria and they are already probably 100 times more bacteria than human cells in your gut could there be an option to somehow coordinate or modify the activity of the bacterial phages to have a positive effect yes so maybe I went too fast on that indeed that is one of the idea why we are trying to control hostage everything the bacterial phages in the end boils down to hostage and this is an extremely complex phenotype to control but yes one of the idea we want is to be able to use the phages to clear up space the bacteria we construct to settle in because direct competition between an engineered microbe and a natural microbe is unlikely to ever lead to colonization so that may indeed result to directly isolating phages from the guts and engineering them the way we want them and so on or that may have to do with phages that we already have in the lab and we just engineer to have a different hostage and we just try it out and we don't know yet what works Do you think that it can be some that's the nutrient that the diet can induce metabolic switching gut-filling says yes gut-filling but I can't think of a paper I read which actually measured that I can think of papers that measured the various so that started from a homogenous population of mice for that instance and then they submitted them to various diets and found out that at the end they had a completely different microbiome but I don't think that was ever correlated to some form of metabolic now the field is moving quickly so it's not impossible to do just dealing with the paper it's a sense of history so yes, there will be some change what change who knows so is it possible to represent the effect of their recombinase or something that modifies the design itself or a cast-9 but that would cut the design and therefore maybe sell something new using S-volume so the question is I'm cathartically active and you represent you want to represent that using S-volume was that the question? I would like to represent that you can modify the original design the design can modify itself yes you can represent it yes you can basically create components for your target as well and then you can add annotations and you can also create an interaction using S-volume entities so there's an interaction between the S-volume you can say that interaction basically represents the genome editing and if there's two participants one is the complex and the second one is the DNA and you can also assign roles to the participants using the S-volume interactions I think that would be sufficient for you to change data just a question on just semantic web technologies in general and the idea of querying across ontologies is there a limitation as far as the with your system as far as I can see or semantic web technologies you're making statements about things so you're saying that this protein is a whatever or a particular molecule is like a fatty acid or whatever statements that you make about things and then you're reading across that is there a limitation though that if you come across there's no way of inferring knowledge from that insofar as you can if you come across with an entirely novel protein or an entirely novel small molecule you can't make any you can't question all that because the system has never seen it before is that a limitation insofar as you can't actually infer new knowledge from this you can just query of what is existing and what is normal that's true, you can only query what you have but sometimes there are data over there you can always see query but you just don't realize that maybe that protein is a specific trap you don't realize that but once you query your database and find that that trap is similar to something else you infer that you have made a candidate but it's that question or similar thing you know what you're saying that is similar to that but what doesn't seem to be it doesn't seem that you can capture that kind of that mental leap that we can make in such a system in our ontology we use, for example, gene ontologies which assigns molecular functions other links that you can capture maybe but I'm not saying we've designed it ontology and we captured the whole domain of the post-internatology I'm not saying that there are most of the things that we didn't capture I just wonder if it could be augmented with more kind of cheminformatics approaches or more biochematic approaches then you've got the knowledge that you know and then you can make the lead that says this command looks like that compound of which I know these facts are that you know that it strikes me that on its own it would be less useful than having this kind of hybrid system where that knows a little more about chemistry and biochemistry yes certainly you can always mine your raw data and then maybe as next wave you can provide some more high level information which can be probably better represented using biological networks yeah but raw data, sometimes you have to do bioinformatics to compare sequences or search for specific and for instance you have to do that, I guess it's not as far as networks are used I can just add an additional answer to that so far when we say ontology as you know in the semantic web standards we have multiple levels of what we call ontology there's a form I call Audible UL actually this is the one you're using and the first level of that language provides inferencing between terms when there are synonyms and stuff like that the two subsequent levels which are considered as being dangerous by the computer science guys are actually doing a little more because whenever they provide some inferencing at two or three or four degrees then they are directly retrofitting that link and creating a direct link so they are like enriching the ontology at query time and therefore there is like an extension of a sparkle language that's the first thing that we are monitoring what we are doing and the second thing is machine learning and deep learning is also now trying to merge with that space so that query inferencing and let's say mining are trying to link together in one system but it's really not the same what you said last time you're implying and this is a curation and it's interesting but this is a curation and quality process back to microbiome did you test a relaxation or recovery capacity of the entity I mean if you course artificially say a diarrhea with the physiological some stuff then how fast the biome gets into the normal condition normal state normal exactly yeah I'm trying to think but it's important to remember that really the microbiome field is extremely young although the word has been used for fairly long time the real quantitative data date back from less than five years ago so this is still extremely descriptive where people take a bunch of samples that may be more or less biologically relevant deep sequence them to find out what kind of bugs they are and that's it as far as I know there is not a single actual follow-up experiment during an actual illness that has ever been done it has which one then both the USA and former Soviet Union there is quite abundant data on spacemen concerning the testinal microflora dynamics and quite number of those data are freely published are not classified and actually those data says that for human being in quite specific conditions meaning some other are classified sure sure quite specific in physiological terms first of all the recovery is quite fast very interesting yes I am thinking as we are discussing so what we see in the mouse indeed is that as soon as we stop so theta is pretty stable but it will get outcompeted after about 30 days actually my question addresses not the theta itself but the composition or combined and gene consisting of a mouse and a theta so if you make some delusion of intestinal microflora then how fast it recovers to the previous normal status well yeah one of the reasons why I have difficulty to answer that question is that I am not sure how to define normal status ever so we actually it was my attempt to understand how you define it so good answer I will just think about what we have done and in what we have done we actually never look at the endogenous microflora so far what we follow exclusively is the engineered bug that we put in it the only measure of the resident the resident microflora we have is the total count on a given type of plate which is an extremely biased measure and some QPCR data where we measure the total abundance of 16S of a specific type of 16S which is theta and in those experiment we actually so the problems we start from streptomycin treated mouse so when we start the experiment we don't have a natural microflora we have something which was heavily depleted so we do have bacteria that survive streptomycin many of them but that's nothing like a natural microflora so what we know is that once we stop streptomycin within about two days the guts are fully colonized with stuff but we cannot define as of now what stuff is and even less whether or not stuff after is the same as stuff before but that's exclusively for what we do and yes the data is obtainable but that has not been a major focus for us in Tiananmen thank you a question for Gokso how do we adapt the S-ball attempt to the bottom up mainstream synthetic biology I have more difficulties with some other approaches to synthetic biology such as top down or pro-cells or whatever and I would like to know if there are some extensions of S-ball in the planning that would top down genome reduction whatever approaches that are not of the bottom up mainstream type my comment would be S-ball doesn't dictate better you to start the bottom up or top down so it's about exchanging your information without losing any information you should be able to exchange your designs and in my lab I should be able to replicate so I think S-ball would still be useful for top down designs if you mean some abstract definitions like specifications S-ball can still be useful it can substitute things where you can create templates but you can even represent the whole genome using S-ball that's perfectly fine and S-ball is idea-based and backed up it turns from different ontologies and we also developed in a way that's really extensive even if you come and represent your specification-specific data with S-ball we have an ability to store your data and during round trips it wouldn't be lost so those kind of entities we call them generic top levels and we treat them as external data and we introduced that concept and we wanted to easily create extensions in the future at one if you don't have a context expansion context information is easily exchangeable for data shift but in the future there will be extensions for S-ball hopefully some group will develop and will devote it to the short track and will say let's expand S-ball with this extension any other questions? still have some time? no other questions? thank you but I have a question so you use this approach of delivering class 9 toward using M-13 which well is a great idea although M-17 as mentioned is calling to use for other microbes but this idea could be used with all the other phages that you are developing like delivering this type of toxins no gases into these bacteria phages but in addition to the addition to the targeting of the bacteria have you considered the replication requirements of the phages in the sense that in order to have let's say a minimal set of phages that could infect many bacteria it's not only the capacity to let's say infect at the beginning but also the ability to replicate inside I don't know if these are very strict for many phages do you think this could be a limitation? yes and no as usual that depends what kind of application of phages you envision if you envision delivery of DNA like the Cas9 system with M-13 and you just want to package it into something else which is better than M-13 then phage replication is not relevant at all there is no phage replication you package your cargo DNA in the lab then you deliver it and then it's just a cassette when bacteria heat type of system then the plasmid design may or may not be replicative that depends on what you want to do with your Cas9 system but the phage replication does not occur, cannot occur that's the whole idea behind phage and maybe I'm not going to say too much about it because I'm guessing that this is what David B. Carr is going to be talking about tomorrow so in this case this is a one-cap set one-hit and if you have a billion cells to kill you need a billion phages and you need each one of them to find its target this is one of the reasons why I don't really like that approach and I am still a big proponent of more classical phage therapy where you indeed use the capacity of the phage to spread once it found the right bacteria in this case there is indeed a lot more than just host recognition to do with replication so bacteria have developed a lot of phage resistance mechanisms outside of simply changing evolving mutating receptors of very different types and of high diversity from strain to strain and it then becomes a question of choosing the most appropriate scaffold so the best one there is but this is also the reason why at some point I mentioned that I don't believe we will make you with a single scaffold we'll probably need a few the idea is to limit as much as possible the number of scaffold we need to use because as Yvonne said yesterday every time you introduce a new component in the system there is one an increased number of risk of failure and second there is an increased cost of being getting it approved tested guaranteed to be okay okay so I hope to thank our speakers for their presentations


Why I am joining the land conference 2021? Because mainly of land issues and the importance of pwendex data. Indeed last year a global survey by pwendex found that one billion people feel insecure about their land rights. This is important in the climate and biodiversity debate because how people feel gives a strong indication of how they will act in the future. 2021 is a big year for the environment. With world leaders gathering at two major related nations conferences to discuss biodiversity and climate change. To ensure this important negotiation of the best outcomes, we need better data on how long-term security affects the shows people make about their land. Global alliance with pwendex can provide this data.