Hi there, my name is Ryan and my name is Allie and we're currently riding bikes across America and this is what we brought Ladies and gentlemen, so you want to go on your first big bike tour or maybe it's just a small bike tour We are here to help you with what gear you might want to bring Allie But remember that the best year is the gear that you've got so the important thing is you just get out there and do it Yes, having fun is the number one goal of a bike tour It is not meant to be a suffer fest You want to go out and explore the world at 15 miles an hour You want to do it comfortably and you want to have some of the right stuff to help you be comfortable So let's get started. We're gonna start off with some of the must-haves and this may seem weird, but Butter knife I've been using a butter knife on every single tour. I've done for the past 10 years What do you use this for you use this for spreading peanut butter or beans? You might be back there saying well, I have a Leatherman. That's fine Leatherman's are great But they're really sharp and they get all gunked up in the peanut butter can in the bottle And it just this is what you want Blinky lights even for the daytime so the cars don't hit you and party time party time Party time. No, these are really really important to have during the day You might think oh lights are just for nighttime. That's not correct You want to have these on at the daytime so cars coming from behind you can see you Because nothing will end a bike tour faster than getting hit by a car really really good Puncture-proof tires. I love the Schwablet Marathon plus tours I've been using these tires on every single bike ride and they really work. They're worth the money I average maybe one flat tire for every tour.  I love this one. It's huge. It's thick. It weighs nothing This small pile right here is all of the clothing we have for a two and a half month tour And it doesn't really matter if you're going for five days or a year This is about how much you want and that means not much Two pairs of chamois so you can wash one and have it drying while you're wearing the other and if you're new to bike touring A chamois means padded shorts You want that because your butt is sitting on a seat the size of this for about eight hours a day I love riding in wool marina wool does not stink like a lot of the synthetic materials So I have one two shirts for any ride like alley I keep one clean the other ones usually dirty and I switch them out usually washing them in hotel sinks Super lightweight rain jacket and just in case if it's summertime and it's warm out You can probably just get away with taking your shirt off in the rain and keeping your clothes dry because let's be honest Who wants to wear a rain jacket if you don't have to but if it's cold You're gonna want to stay dry and stay warm marina wool long sleeve sometimes at night time It can get a little chilly and it's cozy You can bunch it up and use it as a pillow in your tent two pairs of socks one's always gonna be dirty I like to have a long pair and a short pair I always have one non riding shirt for when you're in a town You have a rest day and you want to look extra patriotic Formal wear for rest days it's a skirt so that your butt can rest because it can get a little bit chafed up from all that riding and Also, it looks just fabulous You go from wearing bike gear all the time to a nice cute little dress and you feel good And a lot of my previous videos you probably noticed that I wear a buff Even when it's super hot like in the Baja and I wear this mainly to keep sun off my neck Of course, you can wear sunscreen, but this works really really well Also, if your hair is getting nasty, you can put this up there and nobody needs to know You're getting very Sleepy hopefully not bored of this video, but these are arm sleeves And I wear them almost every single day again to keep sun off my arms And when it's really hot out you can dribble water on them and they feel really cool on your arms Bathing suit because Ryan told me I'm not allowed to skinny dip in public places Biking sandals. Yes, they make them with spd's on the bottom. These are made by keen There are some other brands that make these I love them because you don't have to pack socks You're not stinking up socks. It keeps your feet cool and you get awesome tan lines I also have a lightweight pair of shoes you could bring sandals But it's nice to have something to change into After you've been riding all day that's a little bit more comfortable than your bike shoes Bike shoes are very hard and rigid these Nice and soft one of my favorite parts about bike touring is sleeping under the stars and camping out And this is our camping gear. Allie. Let's start off with the tent Kent, this is a little two person one. It's so light. We love it. And you know what?  We brought along a coupler and it makes our two sleeping pads into one So that we can be cozy lightweight sleeping bag that can be scrunched down to the size of a football We love this thing at the beginning of the ride We had two of these and we zipped them together to make one gigantic sleeping bag that we could be all cozy in As it got warmer as we went through the midwest We sent one home and we just have this one bag We unzip it so it's like a big blanket and it is perfect water filter This is important only if you're going to areas where you're gonna have to pump your water If you're going town to town and you're able to refill frequently Probably don't need one of these but if you're going to the back country, it's a good idea You probably want some sort of light in camp. It could be a headlamp. It could just be your phone I love these lucy lights. They're solar powered. They last a long time. They're inflatable They scrunch down to nothing and you can hang them up from trees and have cozy little camp situations Stuff sacks. This one is waterproof. Ryan has different solutions. I like my stuff sacks I bring lots of them and put everything in its own bag. So I never lose things I get really high tech with my stuff sacks and I use Ziploc bags Works pretty much just as good toiletries. There's a lot of stuff in here. Some people might think it's too much I think it's just the right amount and it's really a personal decision What you need to say comfortable and feeling fresh And this is how I feel fresh. It may seem silly to bring an electric shaver I use it every single morning. I keep my face nice and smooth It makes it a lot easier to put on sunscreen and to kiss Ali Cameron here, you probably want to document your ride in some way It might be as simple as just using a cell phone.  These things are awesome. They're so fast It's got the thunderbolt. Also, it can really take A bit of a bang in you maybe careful with that And it still keeps it on a chugging.  Here's the backup drive Laptop for on the fly video editing. This is totally unnecessary, but it is a kindle for nighttime entertainment Right here your phone Super important. We love these are good for taking photos and videos and most importantly Google maps We're not following a set route on this ride and essentially every day We pick a to b on google maps. We hit the little bicycle function here It gives you the safest roads to ride and for the most part Google maps knows what it's talking about. It sent us on a lot of really amazing low traffic roads Keeping all of this stuff charged is Kind of difficult and there's a process to it and that we usually go to cafes or restaurants for lunch And we find all of the open plugs and we plug everything in every single day So we just got to stay on top of this stuff. You want to bring some extra batteries and usually you'll be fine Free extra cords too because you need those cords to charge with and they're going to break Now if this was a more backcountry adventure We might bring a solar setup, but those are also fallible and they're a little bit more weight So if you can avoid it just plan on poaching power where you can get it charge box for your phone or whatever If you run out of juice, it's good to have a couple of these handy. You're going to get sore muscles It can't be avoided Everyone's got their favorite tools for self massage mine happens to be very tiny and easily replaceable for 25 cents You can hold this and like press it into any kind of a A point that's not letting go you can roll it on your muscles If you find a good wall, you can just kind of like roll yourself against it with the ball They're great and they're also fun for entertainment purposes. You can bounce it. Who doesn't love a bouncy ball boy You can give it to a small child cats love them.  We fit all of that stuff into two rear Paniers panniers, however you want to say it and we keep one up front for Both of us mostly just photographic supplies and the occasional other little thing These guys right here are completely Waterproof and they're pretty light weight on all of my rides. I keep all of my food in a separate bag This is where the beans go the cans of peanut butter the nutella The tortillas what else goes in here sometimes candy cliff bars Fritos Fritos you pack this thing full You lock it down and you know when you unpack for lunch You just pull this out and your food is all in one place and easy to find helmet You want to choose one that you're going to want to wear this one is super lightweight. It's comfortable It's white that means that my head doesn't bake when it's hot out It's really breathable and it's fashionable with its little brim.  Why do we like that?  So you want to pick one that's really comfortable They make ones that are women and male specific that have nice little places cut out for the private parts Some people are into the leather brook seats that take a while to break in remember Choose one that's going to work for you and ride in it for a little while before you go on tour with it And don't forget the most important thing to a bike tour is indeed your bicycle Pick a bike that you've had for a while That's comfortable for you and is right for the terrain that you are going to ride on on this ride We've been riding trek checkpoint. It's a gravel bike. It's great for mild off-roading I will do a complete review of this bike in another video. It deserves its own video because this bike is awesome It's good to have an official trip mascot. Maybe it's a chihuahua Maybe it's a love bug ours was gifted to us by our friend sarge We met at the motorcycle rodeo in Idaho And he has come with us all the way across the country and he keeps us grounded reminds us that we're on the same team The bug gear is a funny thing You can definitely go down a rabbit hole of gear and spend tons of money on this stuff But let me tell you my very first bike tours like the first five tours I ever did I had hand-me-down stuff and nothing expensive at all and I was just fine Yeah, don't ever let gear or lack of it stop you from getting out the door just Put your backpack on get on your cruiser and ride if that's what it takes to go on that that tour It really doesn't matter. You can spend all the money in the world and fancy gear There's always going to be something newer and fancier. So why try to keep up? We are very fortunate that a lot of these brands Give us this stuff because they're in the videos and blah blah blah blah and we appreciate all their support I'm putting a list of a lot of the items that we've been talking about in the description of the video So if you want to go to the specifics and find out where to buy this stuff go into the description of this video Most important thing just get on your bike ride it and have fun and smile and splashing water and eat peanut butter and beans And sleep under the stars. What else? Just have fun.  It's about the places let you go Yeah, and the beans that you eat if you want to watch the videos from our entire tour across america They will also be linked down below Thank you for watching Like and subscribe Like and subscribe seriously if you subscribe I guarantee you're gonna have a lot of fun I have videos from all over the world bike tours and running and trekking in the mlas and all sorts of good stuff You forgot to buckle your helmet. Oh, thank you Safety first


Hey guys, how you doing? This is your boy rich from rich TV live and you too can join the club at rich picks daily calm Where you can learn how to win and trade Hey guys, how you doing? This is your boy rich from rich TV live and rich picks daily calm Where you can join the club and you can win big we identify early-stage crypto currency projects 24-7 seven days a week and we found another one algebra dot finance and Imagine if you as a trader could earn commissions For liquidity. That's what these guys are doing. I can't believe it. I've been dreaming about this for years create an opportunity for all crypto holders to provide liquidity for trading and earn commissions from the trades brilliance Users of algebra dot finance can swap coins and take part in farming events to earn extra incentives for providing liquidity and Guys, they're gonna be launching soon. Take a look now Just remember rich TV live is strictly for information education purposes.  It doesn't mean the next Program platform Project is going to be a home run, but we like this one. Let's take a look algebra Dot finance release on the 15th of December one day 13 hours 55 minutes and 50 seconds until the release Getting the best AMM solutions for polygon and finance and smart chain We are all excited about uniswap version 3 Algebra's goal is to create similar AMMs for other leading blockchains not to copy but to reinvent and improve You can check out their tech paper go to their app now I want to show you guys some of the different communities they have because cryptocurrencies are all about communities This is the algebra decks community on telegram. You can see 407 members online 3919 total members on telegram. This is them on Twitter 2873 followers on Twitter see innovative decks on polygon Matic built-in farming and adaptive fees So who is algebra dot finance? This is once again their telegram and This is them This is how you can actually enter your wallet and swap right here for Matic This is their website at algebra dot finance They're also talked about on medium We'll go through that in a bit and they're also on YouTube as you can see here 146 subscribers on YouTube Watch a quick video here a tutorial So they have videos and tutorials and they're on YouTube I'm not gonna go through it But you guys can go through it on YouTube and learn more about Algebra dot finance You can see here. There was only just a few days until the beta release of algebra So it's time to inform you on our latest news. This is on medium Here's a short list of the new features We have added and changed in order to make our work even better You can see they're working on lots of development and There's an ambassador program so you can be an ambassador for algebra and help them grow This is all on medium. All right, so that's them on medium. This is their website. So who are we? Our team has released several crypto projects since 2017 such as Rubik Multi-chain DeFi platform for Polygon, Binance, Smart Chain, Ethereum, Xdai, Tron, Harmony, Phantom and others Another project is my wish the industry leading platform for building smart contracts across 11 different blockchains Ethereum, Polygon, BSC, Neo, Tron, EOS, RSK, waves, HicoCoin, XDC, Moonriver and Solana Our team is well known in the crypto industry. We have won many grants and partnered with many large crypto companies So Algebra is an innovative version 3 decks on Polygon You can see the team here will go through, you know, all the different members. You can see they're so they're fully transparent, you can see there it combines best practices from the existing market solutions like concentrated liquidity and deflationary token support and introduces new mechanics built in farming and adaptive fees for more profitable decks use You can see who they're back by here So they support concentrated liquidity on Algebra.finance You can see the expected volume in 2022 with Algebra Version 3 when you compare it to other platforms Like pancake swap who they're anticipating they could do potentially more revenue than in 2022 and Algebra versus quick swap who they're anticipating they could do more than as well. So Enormous revenue potential here for Algebra.finance. The volume forecast is Enormous so on Algebra your liquidity isn't traded on the whole range from 0 to infinity What keeps being traded on a specific price range you choose your own So you can see here the main characteristics best curve formula suitable for both high and low liquidity tokens Earn up to 0.02 for every trade as a token holder Extremely simple UI and friendly UX Discount on platform fees for token holders, Dow implementation for making important decisions, WebKit for integration to any project site exchange or wallet So those are the main characteristics you can see here What will Algebra do differently liquidity positions set the token price when liquidity is available Built-in farming makes it fully unique. No need to farm LP tokens by using external smart contracts Fees curve also unique characteristic trading fees for pools are adjusted automatically based on trading volume pool volume and volatility Coming soon smart routing partition between pools with consideration to gas fees Cross-chain bridge integrations for cross-chain swaps and for providing liquidity by using Rubik coming soon and limit orders coming soon ox and Rubik integration for limit order execution Algebra has received a grant from Polygon and you can buy the Algebra token using Just connect your wallet and you can buy the Algebra token using Rubik once again one day 13 hours 49 minutes and 13 seconds until the release on December 15 You can also go and check out their tech paper. You can go and check out their app Let's just quickly look at the app. It goes right here. It's the Algebra app. You can see pool farming Migrate and info so this is all just getting started. We're really pretty much new to this. This is brand new getting started You can see liquidity pools Tokens So they are just getting started and you can see that the platform is Just getting rolling so love to know what you guys think about these videos If you like these videos smashed like button comment down below share the video everywhere and subscribe What do you guys think about Algebra dot? finance Love to know what you guys think about Algebra dot finance Pretty cool token swap farming Everything you need to know all in one place here at Algebra dot Finance you can go and check out their tech paper right here and one thing I like is that it's a decentralized exchange so Everyone needs to understand the Algebra decentralized exchange Dex and with their other Dex's and what Compares them and makes them different is their approach to Decentralized trading the key differences between Algebra and other exchanges are dynamic fees built-in farming and Deflationary token support. We're taking a closer look at these features and exploring exchange users benefits So I'm not going to go through all of it, but the major focus is dynamic fees So lots of information on liquidity and all of this can be found on Algebra dot finance So obviously when you're trading liquidity is a big part of it These guys are really helping to improve Conditions you can see here optimal conditions all participants interacting with the Dex can be divided into three categories regular traders arbitrageers or liquidity providers So like I said, I'm not going to go through the entire tech paper But you can do that at Algebra dot finance and just click on tech paper so What essentially means is that all your trades are made by actual prices and the fees you earn are the best on the market They also have dynamic fees They are created a special formula calculating fees based on volatility trading volume pools Pools volume and if you are an LP You don't need to choose the right pool out of three as you do on uniswap version 3 in order to get higher fees Their formula does it automatically for traders that guarantees the lowest slippage So once again Algebra works on the polygon platform Okay, and it makes trading experience better more Democratic and suitable for common investors due to close to zero network fees So less fees better for the investor high throughput and transaction speed and high level of reliability on Algebra dot finance you can swap tokens Provide liquidity and take part in farming Starting from less than a dollar. It's impossible to imagine on Ethereum with its extensive Dex So this is what makes it so unique and so much better Algebra is creating an established company experience in crypto and D5 fields the team behind Algebra has created Rubik Multi-chain Dex aggregator and my wish multi-chain smart contract building service and as a community of dedicated Supporters the team is public their faces can be found on the website, which I've shown you guys Algebra Dex has received a development grant from the polygon polygon foundation and is supported by several major Venture capitalists they include NGC LD gains DCI GTA venture CSP Dow and Dow capital So a lot of interest already in Algebra dot finance All right guys, so I must remind you that rich TV live is strictly for information and education purposes You can see here. These guys have one grants from polygon have one the Tron Accelerator winner and waves grant winner and the Neo Foundation partner. So already having a lot of success with their peers they have a max supply of 750 million coins and they break down how they will distribute all of these coins 33% of fundraising 18% to the Treasury fund 28% to liquidity mining allocation and 6.7% to Wish and RBC holders So Algebra is the first Dex supporting concentrated liquidity on the polygon network You can see 4% of the coins will be going to advisors 2.6% to listing pool allocation, which is 20 million coins and 6.7% of the coins will go to the team 50 million coins out of the total 750 million coins So they know exactly where every single coin is going All unsold tokens will be burnt This is very important for cryptos that they burn Tokens which reduces their supply and is very bullish and typically makes the price go higher other groups marketing advisors team, etc to be decreased Proportionately so some of these areas will be decreased proportionately and those tokens will be burnt This is their roadmap so you can see Where they've started and we can go find from the bottom All the way to the top and see August 2021 MVP release September 2021 security audit started November 2021 alpha release on polygon Farming LP program started December 2021 beta release on polygon and Q2 2022 beta release on Benance smart chain Pretty cool So they are not a fork but an innovative next-gen exchange picking up the best practices from the market and Introducing new features that make LP farming more profitable. They developed built-in liquidity Farming instead of using other services which allows Their users to earn more Secondly, they refuse the idea of using three fee pools with different profits depending on risks and offered a unique Dynamic fee model that calculates the fee depending on many factors including the degree of risk trading volume pools volume volatility Etc. So they have a very dynamic System it eliminates the possibility of error from the side of customers and makes both swaps and liquidity providing more profitable Clearly they've had a lot of success. They're getting all kinds of grants and You can see the team has already released several projects Rubik and my wish so they've already had success So they're focused on making liquidity providing more profitable and Preserving the technology of concentrated liquidity Presented by Uniswap version 3 now your liquidity isn't traded on the whole range from 0 to infinity But keeps being traded on a specific range you choose on your own Which essentially means that all of your trades are made by the actual prices and the fees you earn are the best on the market Finally you start on polygon with a plan to expand to other networks within a couple of months so that's the team And what is the main advantage that the end user can receive with this project An adaptive fee one of the key advantages of algebra is an adaptive fee, which was created by this team right this team is what's making this possible And that is required to maximize the profits both for liquidity providing and for users LP does not need to choose pools and move liquidity between forgetting the highest fees or unique formula Their unique formula calculates everything automatically Traders also win since all liquidity is concentrated in one pool, which guarantees the lowest slippage They also have built-in farming Introduced built-in farming for LPs projects on polygon will be able to push extra tokens To pools for incentivization and set farming conditions start end dates, etc Extra tokens must be distributed to to all LPs But proportionately to liquidity Used in trading the amount of the reward that a particular LP will receive depends on time While liquidity was in the price range in which the trades took place For proper reward calculation for each campaign participant algebra invented an entity called a virtual pool So a virtual pool is a simplified copy of a real pool It is used to track the time when the liquidity of different providers is active So clearly this is a huge volume forecast With this focus in mind creating liquidity And a deflationary token support is another aspect of algebra that they're providing So definitely put algebra dot finance on your radar put on your watchlist One can swap deflationary tokens and create pools with them So pretty cool what these guys are doing And I'd love to know what you guys think about these videos you smash the like button Please comment down the video. Have you already invested in this project? Are you thinking about investing in this project? They are ready to launch literally Any day here it is one hour sorry one day 13 hours 37 minutes and 19 seconds On december 15 literally one day and hours away from launching Love to know what you guys think about this. This is a decentralized exchange On their decks people can swap tokens create liquidity pools Add liquidity to earn fees and participate in farming for incentives Different projects on polygon will be able to push extra projects Tokens to pools for incentivization and set farming conditions. What do you guys think about algebra dot finance? You're more rich from rich picks daily and rich to be live And you can go once again and follow them on twitter. I am following them on twitter You can swap tokens farm Obviously, this is just getting started and you can follow them on telegram


the last presentation. I wanted to talk about a patient that I saw in Dr. Burstein's clinic when I was a second year, year and a half ago, and this is really one of the best patient encounters I've had in residency. So I'll always remember this case. So this is a 16-year-old male with the history of a high myopia was referred to Dr. Burstein's clinic for a workup of RP. So his mom says that since he was a kid, he kept on running into things in the dark and he really didn't like playing outside when it gets dark. It's part of the RP questions. You ask whether he could see the stars and he said he really couldn't. So for the last several years he was told that he likely has retinitis pigmentosa and that his vision will get worse. But he says his vision's been stable for the last several years. You can see well in school and actually does well in school but he was instituted low vision training including braille and mobility for the last several years. So he was learning how to braille, how to cane, after classes he would go to extra classes.  He was just seeing fine. So otherwise pretty healthy kid. He did have a history of a right oral blowout fracture three years ago that did not require any surgeries. He has a high myopia with minus 16 in the right and minus 17 in the left. Where's contact lenses and he has a history of exotropia and stratospotia business surgery. His family history is very interesting. He has a maternal male first degree cousin that was diagnosed with RP at the age of three or four and this is actually the son of his mother's identical twin sister. The patient has four siblings and none have vision problems. I don't know the history of this of this cousin that he has. So his examination in clinic, his visual acuity was 20-30 in both eyes of Pinhosa 2020. The anterior segment examination was unremarkable. The dilated fundus examiner shows tilted in myopic optic disc and there's a mild pigment modeling in the macula. There's these dots that you can see in the mid periphery that's just artifact from the camera that you would usually see in high myops. I talked to Jim about it this and learned as well. But just to point out there are no bone spicules that's characteristic of a retinitis pigmentosa and the vessel seems normal. Macula OCT was normal and the Goldman visual fields were full in both eyes. So as part of the work up we did full field ERGs and just, you know, I think we're all, we've seen this print out and I just wanted to review a couple of things. And just to remind everyone the conditions that Dr. Creole uses. So the first five, one, two, three, four, five are done under scotopic conditions.  And then the patient is light adapted for at least five minutes and then you have the photopic ERG measurements which is the single white flash and then you record the ERG from it and then of course the 30 Hertz flicker for cone function. So these are all very important to look at but I'd like to draw your attention to these scotopic condition, the bright white flash. And what we can see is that the A waves are normal but the B waves is highly attenuated. It's about 81 microvolts in the right eye and 91 microvolts in the left eye. You know, this should be around 500 so the B waves are highly attenuated. So, and this suggests that there's abnormality in the bipolar cells. So the differential diagnosis right away with this is on top is congenital stationary night blindness, retinitis pigmentosa, rod cone dystrophy, vitamin A deficiency and especially for the residents and for us to review. What you call when the B waves is gone and what you're left is just the A wave is an electronegative ERG and the differential diagnosis for this is very small including CSNB or congenital stationary night blindness, melanoma associated retinopathy, X-linked juvenile retinoschesis and CRAO and CRVO. These are mostly tested for boards. So we think that this patient has CSNB. So this is a non-progressive disease. X-linked is the most common which, you know, likely explains that his cousin likely also has a X-linked congenital stationary night blindness, but it's also been reported to be inherited autosomal recessive and autosomal dominant. This is a rare class of diseases and we do not know its prevalence, but we do know that it's been reported in all in all races or all racial backgrounds. Visual acuity could be highly variable from being a very, very good visual acuity to 2020 to not very good in 2200. And the important associations include high myopia and stagmus and strabismus. Again, our patient has very high myopia and strabismus. So one of the main points I'd like to point out today is that CSNB is a genetically and phenotypically heterogeneous group of diseases. This is not one disease and you can classify this as types with normal fund disappearance and abnormal fund disappearance. In the normal fund disappearance, we have the Riggs and Schubert Bornstein types and with the fund is abnormal fund disappearance, we have fundus albipuntatus and Oguchi disease. And these are also part of the differential diagnosis as well. And these all carry the classic electronegative ERG response except one of them. So the question that we have is, you know, how can we distinguish the types especially in our patient? And this is mostly an academic exercise. And really it's ERGs. So in the Schubert Bornstein, we know that it's what's hit is by our bipolar cells. And we see the electronegative scotopic ERG again, the normal A wave with a decreased B wave that's shown in here. And, you know, this is really flat B wave. Our patients will hide like a little bit. The Riggs, we know that the mutation is mostly have problems with photoreceptors. And so the ERG shows basically absence of the A wave but have a robust B wave response. And this is all scotopic conditions. And to make it a little bit more complicated CSNB is associated with 17 genes now. And these are all the genes that I found in the literature. And the proteins that encode are localizes to either the RPE rods and bipolar cells. In X-link, which is the most common inheritance pattern, there's only two genes associated. And it's Nix and the CACNA1F. And they're both localized to bipolar cells. So Nix encodes a protein, Nectalupin. We don't know its function, but we know that it's involved in transmission of signal from photoreceptors to on bipolar cells. This is associated, we know that it's associated with a complete form of CSNB, which I'll talk about in the next slide. But this has a preserved cone function. The CACNA1F is encodes a voltage gate and calcium channel sub-unit. And it's associated in contrast to Nix, the incomplete form. And both rods and cone signaling are both affected. You know, we're always tested on this. And it's always a little bit confusing. But just to or yet, you know, especially for the resident, complete CSNB at least historically has been defined electrophysiologically. In scotopic conditions, you see complete CSNB as complete absence of both A and B wave. In the incomplete form, we still have the B wave. And that's, you know, the terminology matches. But when you look at the cones in the complete CSNB, the rods are basically abolished or rod signaling to bipolar cells are abolished, but the cones are not. So you still see a 30 hertz flicker compared to the incomplete CSNB, where both cones and rods signaling are affected. So it's a little confusing the terminology. So the question is, how about our patient? So it's scotopic condition, you know, it's pretty flat, consistent with complete CSNB. In photopic conditions, we do see that, you know, a small B wave, again, consistent with CSNB. In the 30 hertz flicker, we have a normal cone response. So we think that this is a complete form of a CSNB likely associated with NICS. Unfortunately, we do not have the genetic test to confirm this yet as of now. So just to just to finish up my talk, I just want to show you pretty pictures of the types of CSNB with abnormal fundus appearance. The first one is a fundus albipantatus, which you see this, you know, lots of yellow in the periphery. This is associated with RGH5 mutation. And some just important facts to highlight are just it's involved in or the pathophysiology involves delayed regeneration over the opposite, and that the rock, you know, the ERG is abnormal, but it can normalize with extended dark adaptation to hours or even days. And lastly, Oguchi disease, this is the rest in GRK mutation, mostly found in Japanese. And what you can see is this, this is a paper with a five year old kid with this like gold yellow sheen of the fundus. She was dark adapted overnight, basically kept in the dark and then took a picture of her fundus and, you know, it normalized. And after 30 minutes of light adaptation, the fundus goes back again. We do not know the mechanism, but this is called the Mitsuo Nakamura phenomenon. So in summary, CSNB is a non-progressive retinal dystrophy that mostly affects males. The Schubert-Bornstein type has a normal fundus with characteristic electronegative ERG. NYX is associated with complete CSNB and the KACNA1F is incomplete CSNB are both associated with X-linked and full field ERG is important diagnosis of CSNB in the workup of retinal dystrophy. So back to the patient. We ordered a genetic panel, which is not back yet.  He's not going blind. And he doesn't really have to do braille or caning that the parents just incredible, like, you know, his life plan dramatically changed after that conversation. So, you know, pretty awesome feeling to tell somebody that he's not going blind. So thank you. Any questions?


Hey, I'm Chris, a founder and a product designer. I help UX designers level up by providing them a toolbox for any UX project. I also help companies and product teams with workshops, from training large teams in design thinking and user experience, to running design sprints for product teams to solve complex problems. If that sounds interesting too, let's set up a call or grab some coffee.


We're going to do something a little different this morning. We're going to sing a new song that came out this week and I just wanted to share the testimony about it on Tuesday night at one of our prayer meetings. Brenna Wheatley, one of our worship leaders, who's actually leading worship from screens this morning, was at the prayer room and she's had issues with her leg for over 10 years. She's had torn ACL, has not been able to run, squat anything in over 10 years and in a moment at the Tuesday night prayer meeting, she's getting prayed over, somebody had a word of knowledge, their knee hurt and walked up to her, prayed for her and she was completely healed instantly. Come on. She hasn't been able to run or bend it in 10 years, she just keeps walking around like, I just can't believe it, I'm healed. She's from Kentucky. She shared that testimony, man, faith rose in my heart and that's one of the most consistent prophetic words I've heard, not just even that radiant over this city, is that there's going to be a healing move that comes out of Kalamazoo that flows to the cities around us and I remember, and I'm not making a political statement whatsoever, but when the vaccine, the first vaccine that left to the world departed out of Kalamazoo and I remember Andrew Cuomo tweeting out, hope is coming for the world and it's leaving from Kalamazoo, Michigan and I remember thinking that man is prophesying and he doesn't even know it, that there is healing that the Lord has had us contend and fight for as a house and she came home, Brenna came home from this miracle and told the story to Megan and she just went to her instrument and wrote this whole song just as a prophetic download and started singing it over Celia and Reese and right now, many of you know, but Lee and Jane's grandkids, Zach and Ashley's kids, Ashley's in the hospital, they're 23 weeks pregnant and we're just praying and believing for a miracle, we need inflammation to decrease for their lungs to develop, for their hearts to be stabilized and we are linking arms together as a family and saying God, this is not Zach and Ashley's battles, this is not Lee and Jane's battle, this is our battle as a family and we as a church have been standing and contending that God is still a healer today, this was not stories we read about, but he's doing it today and when he did it this week with Brenna, I said God, you are wanting to stir this and so I heard this song like two days ago, we don't typically just kind of do brand new songs that take time to develop, but we felt like this was a prophetic song for us to sing and after the song is done, we're gonna pray and intercession and contend for Celia and Reese and believe for the healings of God, amen, amen, amen, let's sing the song, Father stir our hearts for faith, stir our hearts in faith. In this moment and I want to urge you, we're gonna pray, don't be an audience member, your voice is just as powerful before the throne of grace is mine, we're gonna join together in one voice and we're gonna pray for Celia and Reese right now Lord, right now we ask for these two girls that are in their mother's womb, Holy Spirit, the same spirit that hovered upon the waters before life was formed on the earth, the same Holy Spirit that hovered over Mary's womb before Jesus was born, would you dwell inside of your daughter Ashley and so Holy Spirit, would you right now bring your healing life and power, the same spirit that raised Jesus Christ from the dead, dwells in Ashley and dwells in that womb and so right now we join together as the body of Christ and we prophesy life, Zoe life right now to Ashley's womb, to these two girls Lord we ask for strong healthy hearts in the name of Jesus, Lord we ask their lungs would develop, Lord that swelling and inflammation and fluids would go down, Lord we ask right now with everybody praying Lord would you put your healing power on display, would you show how much you love your sons and daughters, Jesus would you display and celebrate your own victory on the cross when you defeated sickness in and death and so we do not plead our own righteousness but the blood of Jesus right now, oh God we are asking right now in the hospital room that you would do a miracle Lord that you would breathe life and wholeness into celion reese right now in the name of Jesus raise your hand faith in the room Jesus wants to heal if you're around if there's someone near you would you just then your hands toward them we're gonna pray in this moment for healing Jesus it's by your stripes that we are healed please your blood over every physical circumstance right now over cancer Lord we're broken and torn limbs Lord over disease sickness and illness oh Lord we believe your blood is more powerful and that your blood speaks a better word than sickness and infirmity and Lord we by your stripes we are healed and so we proclaim healing right now to every sickness and every ailments oh God would you show us your power oh God would you show us your power we've heard of your act but Lord we want to see it in our day and right now Lord even those online who are suffering physically healing presence and power Jesus speak the word and you and we will be healed


theCubeSiliconAngle.com, wikibon.org, exclusive coverage of HP Moonshot in New York City, special event as they announce their next generation major inflection point seminal moment in the server data center market, introducing some killer technology, has some amazing stats, we're here to break it down. I'm John Furrier, the founder of Silicon Angle, joining my co-host. I'm Dave Vellante from wikibon.org. Laurent Clerk is in the house on theCUBE. He's with CGG, he's the vice president of IT at CGG. Welcome to theCUBE. Well, thanks for having me. Oh, you're welcome. Tell us about CGG. It's not a company that's a household name, although it's quite an interesting background. Yes, indeed, CGG is a geophysical contractor, so what we do basically is we acquire, process, and deliver images of the underground. Our clients, typically, are the oil and gas companies, and what we do with that, obviously, is they then look at it and figure out what they want to do in terms of drilling or finding oil and gas. Yeah, so talk about how you do that today from an IT standpoint, what your infrastructure looks like, your applications, and we'll get into sort of where Moonshot fits in, all this. Yes, definitely. What we get from the field, and we do acquire data ourselves, that's one of the activities that we have, what we get from the field is a fairly large amount of data that if you look at it without doing anything to it, it is next to impossible to interpret. So there is a step where you take that data and then you process it and you refine it to the point where you get an image of the underground that you can actually understand and use, and that requires software, obviously, and we do design our own software, but that also requires a fair amount of processing capacity, both IO-wise, we have a lot of data, a lot of throughput. Typical data set is in the range of 10 to 100 terabytes, and then a lot of processing that goes with it. Typically, our type of activity is very, very similar to what you find in the other high-performance computing environments. Right, so that makes it well-suited for something like Moonshot. So maybe you could describe your current infrastructure today and then, as I say, we could talk about where Moonshot fits. All right, well, historically, we went from a very large system such as the craze and even convexism, then we moved to mid-range servers, and then finally, at some point in early 2000, we moved to clusters, just like pretty much everybody else. And the clusters we have are clusters that are designed around processors that are capable of doing a lot of floating-point operations. And the network that feeds the data to those nodes is designed around, typically, a 10 gig today, 40 gig for the connection between the switches. So it's a pretty large set of these. We have thousands of servers, literally. We have a number of data sets, data sites. We have probably an excess of 40 sites today around the world doing processing. Not all the same size, but... And they are basically designed to do number crunching of large data sets. And are the servers fairly underutilized? Is that fair characterization or not necessarily? What do you mean? I say, you know, the processors, are they underutilized in terms of... Well, no, not really. What we try to do since we own the software as well is we try to develop the software in a way that it's going to work well for the hardware that we can acquire. And actually, that's where the moonshot is a significant change for us. Yeah, I also explained that. Well, typically up until now, you were bound by the design of the hardware systems as they are. There is some flexibility, obviously. You can change some components. You have a wide range of CPUs. But basically, it's a box with a CPU and then some cards connected to the box. And you had to design your software around those constraints. With a moonshot, you now have a box of components that you can mix and match and you can then look at your software in a different way and say, well, what would work well with what in terms of hardware and then acquire just the bits and pieces that you need and make them work together well? Yeah, okay. In the natural resource area, I was asked a question last week. I was on a panel leading a disruptive technology and the energy question came up and we talked about, say, big data, convergent infrastructure for lead infrastructure. And it's not an area that we cover deeply, but I wanted to ask you a question around that world that you live in in terms of what you need from compute and software at the scale. Kind of give us a picture of the kind of scale that you do and what does it do for your data center? Is it a lot of big data? Just take us through the use case real quick and then how moonshot fits in. All right, well, typically today, the infrastructure that we've developed and deployed in our sites is well into the tens of petabyte of storage and we're well into the, well, terabytes, teraflops of processing capacity. So these are pretty large sites. They are not as large as what you would find in the very large web server forms, for example, but they have the next step behind in terms of size and complexity. But they are not so much dedicated to transaction work like most of the very large sites. They are really dedicated to number crunching and we funnel through that architecture a massive amount of data that goes through a number of different processing steps that are all CPU intensive. So we have all the complexity of not just moving data through that but also processing it in terms of scientific processing. So really we have all the problems at the same time and that is why a flexible architecture is going to enable us to have just enough of what works well for each and every cell. The data pipelining and the compute, obviously, big, big thing. What about at the application layer latency and any kind of SL requirements around latency? Well, a lot of what we do is steal batch jobs because their nature is such that they are very long. So all of the batch activity what we want is make sure that it actually works and works well and is stable. There's not so much a latency issue in terms of how quickly you get the data. But it's raw machines that you need. So in this case, this is nice for you because you get 1800 servers on a chassis. It's perfect. And how about the power? What's your take on the power? You've got a chance to kick the tires on this product. Explain to the folks the order of magnitude difference between non-moon shot and a moonshot box. Well, it's still very early in that process. So I'm not going to be able to give you numbers like HP could. However, what we're seeing definitely in terms of power is that all our processing centers are power bound just like everybody else is. Be it because regulations force us to take a look at it or just the financials of the equation. It's expensive to buy all that electricity. So we have to be very careful about the way we use the electricity and definitely anything that is going to save electricity for us is not just going to enable us to get a better price performance point, but it's also going to enable us to have more equipment to produce a better picture for our client. Yeah, more Protestant. Yeah, because at the end of the day, all about our clients want to be able to see something. So what we need to do is produce the best quality data that we can so that they can then see what they want to see in there. How about just in terms of your supplier relationships? Obviously, you're an HP customer. Are you primarily an HP shop? Do you have a diversity of suppliers? We have a diversity of suppliers. We do work with the suppliers depending on the technology that they bring to the table. And HP with the moonshot is bringing a technology that's definitely very interesting. So it would be, and we couldn't afford to miss that opportunity. So we're working with them on that, definitely. Yeah, okay, so it's not a case of you're okay, we're an HP shop, anything HP comes out with, we buy, it's more opportunistic with regard to the technology that's coming. And the applications that you've cited, they're HPC-like, if I can say that, right? So they lend themselves well to this type of architecture. Do you see things like moonshot applying to more traditional IT? Well, the beauty of moonshot, as you've heard with the previous people that you've talked to, is that it is not so much, I'm getting the CPU, I'm getting this memory, I'm getting something where I can put pretty much anything I want. And if I don't find it, I suspect that you can go to HP and say, hey, there's a market for that, can I have that particular product in there? And so, yes, definitely, I see that box being pretty universal in terms of usage. Which for us makes it interesting because we're a niche market, so it's very unusual that companies will spend the money to develop something specifically for a niche market. So if we can piggyback on a much broader market to get the things we need, that's even better for us. You're obviously, at least in part, a data-driven organization. Are you having conversations internally about different ways of monetizing that data and how is that changing over time? Well, you know, that is not an area that I really feel comfortable discussing. There is more sales and marketing and I don't normally participate in those conversations. So that's interesting because to the extent that sales and marketing are gonna drive that and they require a technology component, would they go off and just sort of do that themselves or would they not consult with you? Or are these secrets that you can't share? That's possible too. Well, there is a bit of, we like to keep the edge that we have to ourselves in that discussion, but basically what we do as an IT team for an organization like CGG is we view ourselves as a service provider internally. So what we do is we listen to the problem that they have and then we come with solutions for them and we tell them here is what we found, here is what we think works best and then it's up to the business managers to decide what makes sense for them in terms of what they sell. From an application development standpoint, how do you see that changing the processes or the way in which they interact with the infrastructure? How do you see that changing over time as a result of things like Moonshot? Well, if you look at the Moonshot as a collection of different parts that you can provision depending on your needs, of course you're gonna have to look at the architecture of the software itself and figure out how to recompose it to take advantage of that. And that could be a difficulty because every time you move to more complex hardware, multi-cores or things that are not obvious, not just a bump in the CPU capacity, then you have to ask yourself what software architecture do I need for that? So there will be some work to be done around that, definitely. Final question, we're getting tight on time here, is what's your overall take of the announcement here at Moonshot and what would you share with the audience around what it means to the industry as folks are just, I mean, you guys are ahead of the curve but there are some a lot of corporate IT departments putting their toe in the waters. They see cloud as in roadmap, they know there's issues and all that good stuff, they're transforming their businesses. What would you share with those folks out there to explain kind of this impact of what Moonshot can do for them? Well, the fact that a well-established vendor like HP comes up with that sort of architecture should enable a lot of people to actually, as you say, put their toes in the water and figure out if that will work for them. And it's pretty much a risk-free operation here. You can work with HP and figure out what you can do with a box and if it works for you, then that's a solution you need. And you got the savings on the energy size, that's a good footprint issue. That's what was good. Okay, we're here inside the Cube New York City Special Edition, breaking it down, we have a lot more coming, stay with us all day. And then Dave and I will also do a wrap up towards the end of the day and give our editorial spin on what's happening and we'll take it from there. So have a great day and stay with us here at HP's Moonshot on SiliconANGLE.com.


Sometimes you just feel a person just needs to be cussed out Right people or things today that just makes you want to just Give them a piece of your mind if you're like me I grew up with parents who cussed I mean, it's almost like they wrote the book on cussing They invented words and I used to cuss myself and tell you how I stopped cussing But the question is is it a sin? Is it wrong for a Christian to cuss to use profanity to use swear words? Well, the first question needs to be addressed. What does it mean to cuss? What does it mean? Well, it is profane words Vogel words offensive socially offensive word abusive foul demeaning derogatory words Oftentimes, let's be honest we use these words even when we're not necessarily speaking ill of somebody else But we'll also use these words almost as an adjective to add some emphasis to the words And sometimes it might be in many cases words or a statement that we don't really Believe ourselves or we want someone else to really believe it. We'll add the blankly blank something Give me the blankly blank. Don't do the blankly blank And it might make someone stand up and notice and pay attention to what you're saying. Is that wrong? Well to determine if it's wrong, where do we have to go? We've got to go to the book and it may even indicate something else that we're probably not paying attention to Paul would say in Ephesians 4 29 says let no unwholesome word proceed from your mouth But only such a word as is good for edification According to the need of the moment in other words, there are times. Let's be honest where it's just something's got to come up and fiddle sticks gosh Dog on it my word Poppy cop g willikers those kind of words They just don't do it sometimes sometimes there is a something Sometimes there's an intensity in you that calls for a word That's just as intense that will just get somebody's attention or just you just want to get off your chest But Paul says don't let unwholesome words come out and let's just be honest guys You know that some of these words if not all these words that you would think that that we would consider to be Curse words of cussing are not wholesome.  Hopefully and so you can control it's not as subconscious as we think matter of fact It's not subconscious. It is conscious We know exactly what we're saying how we're saying it oftentimes it is fueled by emotion And if a person doesn't have control of their emotions doesn't have self-control Well, it might be the fact that there's a bigger Greater underlying problem there. We'll talk about that in just a little bit Peter says in first Peter 310 He says the one who desires life to love and see good days Must keep his tongue from evil and his lips from speaking deceit It's your tongue control it. It's not that big and I understand sometimes All the time we all can relate it gets us in trouble. We shouldn't let Cursings come out and then at the same time later on let blessings come out from the exact same Well from the exact same mouth that should not be especially for believers James tells us in James 3 that we blessed with it. We bless God we curse folks That's just duplicitous. That just speaks of something. That's just not right If you are Christian you want to do as Paul says in 1st Corinthians 1031 He says whether you either drink or you can just speaking Whatever you do do it all to the glory of God. Give no offense He says in 32 give no offense either to Jew or Greek give no one any offense because of what you said Just as I also verse 33 Please all men and all things not seeking my own prophet But the prophet of the many so that they may be saved the goal of what I'm saying with the goal of what's coming in my mouth Ultimately is that it leads somebody to Christ and let's just be on some time throwing out a few choice words curse words swear words We know that's not gonna bring someone to Christ, but it just felt good to get it off my chest Well, hopefully it doesn't feel that hopefully there's some remorse when it happens I understand there are some people that are still struggling with it And if you still do cuss if you still curse if there's a occasional and I hope it's occasional not all the time Word to come out of your mouth. That's not edifying. I pray that for you It's convicting that it's bothersome that you don't like that that shows at least a level of remorse a level of repentance That's taking place in you now when I said this might be indicative of a bigger problem an underlying problem We know that self-control is a result or a fruit of the spirit But if you can't control your tongue if you can't control this urge to cuss and it comes out What does that speak of Jesus puts it this way in Luke 6 45? He says the good man out of the good treasure of his heart Brings forth what is good and the evil man out of the evil treasure of his heart bring forth What is evil for his mouth speaks what that which feels his heart? So if these curse words are coming out where are they coming from out of the heart if you squeeze a Lemon what's coming out of that lemon? Well, you might want to say lemonade, but really Whatever's in it. I said lemonade really lemon juice But what's gonna come out is whatever is inside if somehow somebody put some orange juice in the lemon Well, then when you squeeze it it's coming out the same thing with us Whatever's on the inside when we get squeezed and sometimes it doesn't take much squeezing for something foul to come out Whatever's on the inside is going to come out and Jesus says what's on the inside that comes out of your mouth That's what's in the heart and so if a person is constantly using cuss words Profane words don't care they just want to just express themselves in an angry fashion It may very well be that we've got a dark situation in the heart and that can be a problem Now if a person is truly saved and it's something they're working on and they want to get past and they've struggled with it Let me share with you what happened with me. I used to cuss and I was the best I was probably one of the all-time greats remember my mother and my father would cuss It was just what what we did. It was just in the house It was part of a casual conversation when my father's addressing me or correcting me Yeah, there's some cuss words coming out and so it didn't shock me when someone else used cuss words That's just what it was But how did I get away from that because the moment that I was away from my family my my parents and I was off On my own and as I was a young adult Yeah, cuz curse words were coming out left and right matter of fact My wife would even tell the story that when she met me She was a little bothered at the fact that I would cuss and I would say I didn't cuss that much and she would look at me crazy Yes, she did. Well, how did that go away? What happened? Well truth be told, I didn't do anything I didn't try to stop cussing. I didn't say to myself. You know what? I'm gonna make sure I don't cuss I'm gonna try to hold my mind to it. No, what I did was I really did what James says He says in chapter 4 verse 7 says submit yourself therefore to God Let me say verse 8 draw near to God and he will draw near to you Well, that makes sense the closer you get to God the further you get away from everything else If you get close to God and there are some things that need to be cleansed in you Who's gonna do it? He will and so it wasn't so much a focus on dealing with that particular sin The focus was just getting closer to him And as I got closer to him my heart become began to change and it changed at a more rapid pace There was some things that I still struggle with that's not what I'm saying that you're not gonna struggle with anything But this right here that's coming out of your heart into your into your mouth into the atmosphere for people to hear Things it's gonna make folks look at you Well, that shouldn't be because we want people to see our Goodness or the goodness of the Lord coming out of us And so even though that might be indicative of an issue with the heart that can be changed Just by getting closer to him and so to answer the question is it right? Is it a sin for a Christian to sin? Well, yes, it is There's just no way around it, but how can you fix that? Well, you can't let him fix it by you going closer to him Hey, man


Myth number 10 love is unconditional. This is a big one First to love is to value in general the most general sense possible. That's what that means To value something is to judge something to be of value by definition To love anyone is to love them on the condition that they are who they are and that they do not become someone you disvalue They do not become a monster over time someone you Want nothing to do it which they certainly can change into an extreme example would be that Hitler's immediate family was not unconditionally obligated to continue to love him When he started slaughtering people If anyone in your immediate family became a rapist Someone that's physically or sexually assaulted people or a murderer you would not in any way And that was the same would be true for anything any kind of friendship or relationship. That's just complete nonsense They have broken the condition that they are who they are. They are not Someone who's a murderer someone who's a killer someone who you want nothing to do with and it doesn't have to be that extreme though The person you love family friend intimate partner Fundamentally changes who they are for the worse.  I mean fundamentally Couple years ago Jason Savage He introduced the concept to me that was profound that in a way. I was aware of but not explicitly or consciously He told me that the pursuit of health is a sign or expression of self-esteem so What's important here is having self-esteem or having fundamental values that are important to you a woman or an intimate partner so Again with with just physical appearances if that changes is temporarily That's not that important. What's more important is that she has a pursuit of health that she is a happy person That you like to be around that you enjoy Not the day-to-day small things that can change for better or worse very quickly It's the fundamentals that matter You just rip off DJ Fuji so Those are the ten myths. That's a crash course in this book and in romantic love Some further reading beyond the book, which is just a psychology of romantic love. You can get it on Amazon Barnes and Noble so on Would be a follow-up book this one that is not very well known, but it's really really good It's hard to find but you should be able to get on the internet And that's a romantic love question-answer book. It's a direct follow-up to the book came out three years later. I want to say It's just as long and it's just a Q&A, but it's really really good and he does it with his wife at the time Another book from him is this is my second favorite book from him right after psychology romantic love It's called the art of living consciously the power of awareness to transform everyday life This is fantastic in general, but in specific as well I believe for romantic love as far as being conscious in your daily life and Bringing just like he says five to ten percent more consciousness and awareness Three interactions to your endeavors to your pursuits in life It's really really good And I mentioned this in specific because he is known as the father of self-esteem So he has like a whole list of books on self-esteem that are really really good But that's what he's mostly known for and books like psychology romantic love and this book they kind of get brushed to the side They're of secondary importance behind self-esteem books from him So I would say first look at these because I think these Not saying anything about the self-esteem books. They're great, but these are harder to find and they're not as they're not quite as Popular or discussed as often You can also check out the author's website at his name. So it's Nathaniel Brandon calm He has an entire section on romantic love that I think is really really good. It has books articles Excuse me and Audios from speeches like this. He gave back in like the 80s. They're great. They're cost a couple of bucks There's MP3's and they're really really good. I would highly recommend them. They're absolutely worth like 995 whatever charges form and that's it. That's my presentation on the psychology of romantic love a Brief introduction to it. I hope you guys have enjoyed it and if you have any questions, I'll be happy to take them. Thanks guys Questions for Anthony Johnson He actually I should have mentioned that There's actually entire section in the book. He starts off. It's actually It's really good, but it's not as good as the rest of the book the beginning of psychology romantic love He goes into history So it's like maybe 30 40 pages on the history of romantic love How it's developed throughout the ages and different cultures and religions and so on and how it's been treated So the book answers that really really well I would say I'm not even sure if this is his exact inclusion, but mine is that it most has to do with religions religions have wanted to control sex for hundreds or thousands of years That's why it's such a big issue or That's kind of Self-fulfilling prophecy there. I think that sex is such a It's such a profound celebration of your life and of happiness on this earth as something that people want to control So to control that they create things And I'm not bashing marriage here, but they create things like marriage. They and then they create certain rules for it and such That sex for example sex outside of marriage is evil.  I don't think any of you are very obedient. So power to you. Fuck. I ain't Does that answer your question? I think it's most it mostly comes down to religion It's not even there are a lot of traditional cultural things too, but most of it. I think with some from religions Does anyone else have a question? No, yeah Okay That guy we go. Oh, actually All of a sudden zero to like three. Yeah How does the psychology of romantic love impacts offspring and Children Not an obligation If you oh, yeah, if you get into it liability more likely Yeah, I think that was for example bigger when I was a child and it's gone away a little bit But you're right. It's still around


to here. This is the midbrain section. If you follow closely, the portion which is posterior to the aqueduct of sylvia, this region is known as the tectal area and the portion anteriorly is known as the tegmentum of the midbrain. If you follow the tectal area, this area is known as the quadregeminal plate. It has got two swelling, one superiorly, one inferiorly. The superior swelling is the superior colliculus. The inferior swelling is the inferior colliculus. The superior swelling is concerned with visual reflexes, like visual body reflex. The inferior swelling is concerned with oratory localization, with oratory processing. Like they say, then there's a thunderstorm going on. You see a lightning first and then you hear the thunder. You see the lightning first and then you hear the thunder. That's what they say. This whole thing is to continue with the story of the pineal tumor, which I was talking about a little earlier. This is the location of the pineal gland. Once the pineal gland to the tumor enlarges, after it compresses the posterior commissure, it can even compress on the superior colliculus in all the structures in this region and then it can give rise to a condition known as perinode syndrome where there is paralysis of convergence and paralysis of upward gaze, because the upward gaze center is situated in this part of the mid-brain and that upward gaze center is known as the rostral interstitial nucleus of MLF. Let's not digress too much. Come back here. The aqueduct of sylvius leads into the fourth ventricle. What are the boundaries of the fourth ventricle? The fourth ventricle is bounded by the pons in its upper half, medulla in its lower half anteriorly. Posteriorly, it is bounded by a tent-shaped roof consisting of an upper half and a lower half. The upper half of the tent-shaped roof is known as the superior medullary velum, which is a thin sheet of gray and white matter. And the inferior half of the tent-shaped roof is formed is called the inferior medullary velum, which does not contain any neural tissue. It contains only pyramid and ependymia, that's all. So this is the boundary of the fourth ventricle. This is the floor of the fourth ventricle, which is also known as the rhomboid fossa. We can see only one half of it because this is a sagittal section. And as I told you a little while back, upper half of the floor is formed by the pons, the lower half of the floor is formed by the posterior surface of the medulla. If you look closely, this front leg structure which you see here, this is the coroid plexus of the fourth ventricle. The coroid plexus of the fourth ventricle is situated only in the inferior medullary velum. The superior medullary velum does not contain any coroid plexus. So this is the coroid plexus. And what is also seen here is this opening where my probe is situated right now. This is the location. This is the location of the foramen of magindai. What is the foramen of magindai? It is the midline foramen through which the fourth ventricle communicates with the cerebellum medullary system, subarachnoid system. This is the foramen of magindai. Laterally will be situated the foramen of lushka. The foramen of lushka will be situated further laterally. That is also known as the pontometallary cistern or the fontan angle cistern. Okay. So these are the structures which constitute the components of the ventricular system. Now I'll say a few words about all the other structures which are visible in this particular dissection. Let's start from below. As I mentioned in the beginning, this whole thing is the brainstem. This portion from here to here is the midbrain. This is the tegmentum of the midbrain. Sorry, one more time it blurred out. Sorry? Do it one more time it blurred. Okay. This portion from here to here is the midbrain. The portion anterior is called the tegmentum of the midbrain. The posterior is called the tectum. The tegmentum of the midbrain, if you see closely, this area here, this is known as the decastation of the pyramids. What does it do? It gives rise to the crisscrossing fibers from all the deep nuclei of the cerebellum. Deep nuclei of the cerebellum. The vestigial, interposed, and dentate nucleus. All those which go towards the red nucleus and the thalamus, they all decasate in the decastation of the superior cerebellar pyramid. I've already described the tectum, the superior and the inferior colic in this. Let's come to the lower part. This section from here to here is the pons. The anterior portion of the pons is known as the basilar part of the pons. If you look closely, you will find that the basilar part of pons has got the descending corticospinal tract, the corticobulbar tract, and it also contains the corticopont tank fibers. These are all situated in the basilar part of pons. This is the site of central pontine myelinolysis. The portion posteriorly is known as the tegmentum of the pons, which is continuous with the tegmentum of the midbrain. This is the tegmentum of the midbrain. This is the site of hemorrhage, which we had described as duress hemorrhage when there's a tentorial conic. Incidentally, if you follow this up, you'll find that the tegmentum of the midbrain becomes continuous with the hypothalamus and the thalamus. Or to put it the other way around, the thalamus and the hypothalamus becomes continuous inferiorly with the tegmentum of the midbrain, which is continuous with the tegmentum of the pons. And finally, this is the medulla. Most of the medulla has been cut here, but if we're able to trace these fibers down, then this portion would have been the pyramids of the medulla, which contains the corticospinal tracts. So these are the structures in the midbrain, brainstem. This portion that we see here, this is the vermice of the cerebellum, the cut section of the vermice of the cerebellum. And if you take a good look at this, you'll find that this has got a central core of white matter with multiple fronts of gray matter. This is known as the arbor vitae for the tree of life. This is referred to as the arbor, this cut appearance is called the arbor vitae of the tree of life, consisting of a central core of white matter with a surrounding rim of gray matter. It has got several components. We shall not describe them. They are not important for us at this stage. Let us continue. This thin membrane that we see here, this is the septum pellucidum. What is the septum pellucidum? It is composed, it's a thin double layer membrane. It is composed of epindima on either side and a thin double layer of epindima with a slit like space in between. This septum pellucidum stretches between the phornix here. This is the phornix and the body and the genu of corpus callosum. This septum pellucidum separates one lateral ventricle from the other lateral ventricle and as you have already mentioned, this is the interventricular foramenum monarum. So this is the structure here. This is our corpus callosum. This is the rostrum of the corpus callosum. This thin inferior most limit, the rostrum continues up as the genu of the corpus callosum. Then it continues as the body of the corpus callosum. This is the cut section. The corpus callosum is much extensive and it continues and ends in the large enlarged posterior portion which is known as the spleenium of the corpus callosum. Take a good hard look at this structure here. This space to be more precise. This triangular space that we see here. This is known as the cistern of the great cerebral vein of galleon or the cerebellum medullary cistern. This is known as the great cistern of the great cerebral vein of galleon. This is bounded anteriorly by the tectum of the midbrain. Superiorly it is bounded by the spleenium of the corpus callosum and inferiorly it is bounded by the cerebellum. This cistern contains the great cerebral vein. The great cerebral vein of galleon runs under this. This sulcus which is situated around the corpus callosum. This is known as the callosal sulcus and that separates it from the medial surface of the cerebral hemisphere of the cortex which we had already described.