All right. Good morning, everybody. Thank you very much for coming today. Thank you for the build teams, the airport staff teams and the media for attending this extremely exciting event, historical event in my mind of the future of this Burlington International Airport. My name is Nick Longo. I'm the Acting Director of Aviation here at the airport. I'm going to introduce, of course, the very well-known folks behind me in just a second. I did want to just quickly introduce the project, this top-off ceremony, which you see behind us. The steel being placed just within the last few weeks. This left-hand picture over here is what you're going to see this time next year when we are hoping to invite you back for our ribbon-cutting ceremony and welcome you to the new facility. Some of these other photos here are what's next in line. We call this our terminal integration project, the TIP project. The tip of the iceberg on what the future of the airport looks like. So again, thank you very much for coming today. I'd like to introduce City of Burlington Mayor Murrow Weinberger for his few words. Great. Thank you, Nick, and thanks for your service to the airport for many years now and for stepping up into this leadership role and for your work on this important project. Yeah, just to expand a little bit on the context Nick just offered, why this is such an important project both for now. It will have immediate impacts as soon as it's open, as well as for the future, this facility has been designed in such a way that as the airport grows and expands, it can be added on to and continue to serve the security needs of the airport. So thank you for joining us to recognize and celebrate this major expansion of the Burlington International Airport with the construction of this terminal integration project. Burlington has been the proud steward of this airport for 100 years now and over that time we've experienced strong support from our federal partners who recognize the importance of having a safe, thriving international airport to strengthen our local and our regional economy and to improve the quality of life for Burlingtonians and Burmoners. And in a moment we'll be hearing from a couple of federal partners, key federal partners, Senator Patrick Leahy who throughout his long career has taken a special interest and stewardship of this facility and we will then be hearing from Chris Nelson who is the Acting Federal Security Director in a moment as well. We welcome and appreciate your partnership and Nick on this project. This project would not be happening. The way that we are able to make this major investment is as a result of the $14.5 million federal grant award from the FAA. I appreciate the work of the entire federal delegation in this but especially in particular to Senator Leahy who again has been a real leader on all airport issues for many years. I'd also like to thank the entire talented airport team for shepherding this vision to reality. I spent 15 years before serving in this role trying to get buildings built know what an incredible effort that takes from dozens if not hundreds of people to get a modern building built. I know the airport team worked very hard to bring this about and I also want to recognize the construction trade team that is represented here today. Engelberth who we have done many important projects here at the airport with and elsewhere in the Burlington community is a key partner here and SD Ireland also is doing important work on this project. The expertise and skill of these teams enable the city to reliably meet the high expectations that Burlingtonians have for quality service and best in class facilities here at the airport. With each new significant undertaking the city takes on we is also a moment to reflect on the challenges the past year and a half that we've experienced as a community, as a country, as a globe really. We are embarked on this project in the wake of this major pandemic and we see the airport as an important pillar of the emotional recovery that our community needs. So many of our neighbors have had to postpone critical life events over the last year and a half the opportunity to visit with family, travel, explore or attend major events like weddings, graduations, births and funerals. The airport being open again and being with growing implements just about every week. Every time we have a trip out of here that ends in a reunion that represents an important and very much welcome return to normalcy. The prosperity of the aviation industry will be essential in advancing our economic recovery. The airport is a hub of commerce bringing visitors to the city and region connecting our economy here in Chittenden County to national and global businesses and the airport is also increasingly a home to many local innovative businesses such as spending everything from skinny pancake to beta technologies just across the parking lot here. So I look forward to being back here for the ribbon cutting and not too long and knowing that the investment in this terminal integration project will make Burlington make the airport here safer, easier to navigate and even more welcoming to visitors. So with that I am really excited that we are joined today by Senator Leahy. Senator thank you for amongst all your responsibilities. We know how much you have you're in the middle of in Washington right now. Thank you for being here and being part of this important event. It's great to see you. Thank you. Thank you, Maril. You know we've talked about this airport so much. And Nick when I was leaving home in middle sex this morning I was saying to myself I remember as a kid coming here and we sort of walked out on the runway and saw people and I told our children I had my first flight when I was a student at St. Michael's growing up in Montpeger by the airport there. I walked out on DC3 and they were singularly unimpressed other than to say did they have airplanes when you were that age dad? But I look at how this has grown and changed over the years. I think of the people who have been here. As you know I'm back and forth here all the time between here and Washington and I think how fortunate we are to have such a great airport. And this does start, as the mayor says it, a new phase of improved travel experience and increased destinations that you can travel around the country. Most people are amazed to think that we have what's a relatively small area to have an airport which is far, far better than much, much larger communities and we will have improvement in the area of security which will make it easier. Most people worry about going through security this is going to be a lot easier I think and it's going to especially happen to things like that early morning flight when you're trying to catch it. But then aviation changes all the time bigger airplanes, bigger equipment. This will allow us to adjust for it because as I tell some of these airlines you come to Burlington you're going to fill up your planes and I think this is going to help a lot. Now as chairman of the Senate Appropriations Committee I've tried to make sure that Burlington had a seat at the table for a number of years investing in terminals for an airport the size of Burlington International was not a priority FAA. Well, they have seen a lot of pictures of Burlington they've heard a lot from me, heard from the mayor they've heard from the airport leadership and talked about it would be nice to change this I usually raise these issues when they're in to talk about their appropriations and so we're able to secure nearly $15 million to make this project a reality. Now that might seem like a lot for an area like this but the fact is this airport is so much better than in cities much larger than in this area and so I think Nick we're going to see more and more improvements I know that and we'll keep on doing it. Mr. Mayor I remember your days when you were on the commission and to this day everything that's happened and the tremendous people we have who can do the work so I know I'm preaching to the converted but I think people have to be reminded what a treasure we have in the airport here in the Burlington Airport it's people I know other senators come up here and they are amazed to have an airport this nice in a small area some who fly into much much larger cities and the airport is nowhere near as good so keep it up, thank you. Since you mentioned the commission it was a privilege to serve on the airport commission I do want to just point out especially because he's walking away we're lucky to be joined today by Bill Keough who is the current chair of the airport commission the commission has been a big part of this project as well Bill thank you for your partnership on this. Bill and I have known each other from when our hair was dark and we had more. Thank you Senator very much. I'd like to now introduce Acting Federal Security Director Chris Nelson of course this project the intent of this project is to improve our efficiencies with security making sure the passenger experience is what we all expect out of Burlington, Vermont our partnership with the federal entity the Transportation Security Administration is daily it's hourly and Chris is a huge part of that relationship so Chris thank you for being here today. Thank you Nick and company, thank you Mayor, thank you Senator thank you Engelberth and friends of the media thank you for being here communicating and fostering relationships with stakeholders within the airport community along with our federal and state partners is crucial is a crucial element when collaborating on a project of this magnitude I'm very proud of the partnership that has been built between TSA, Vermont and our partners it has allowed us to successfully work together and navigate challenges in both day-to-day operations and large-scale developments such as this checkpoint reconfiguration project I'm excited to work alongside Acting Director Nicholas Longo and his team as we continue to focus on the mission of providing safety and excellent service to our traveling public thank you. And just to wrap things up a little bit I too want to reflect a little bit on how we got here today both with the leadership of Mayor Morone Weinberger as well as Senator Patrick Leahy I reflect two or three years ago working with you and your team on how to make this building a reality it was not easy, it was not easy for your team I assume and for our team a lot of people, a lot of thought and design went into this building just to be eligible to receive these federal funds Senator Leahy's office made that a reality for us the intent behind this building is truly to capture a more secure, a safer airport and a better experience for the traveling public there will no longer be two TSA checkpoints there will be one checkpoint which is this building there will be additional hold room space additional seating, additional capacity for potentially new airlines new entities, new concessions new future of the airport and I'm so excited to present this today to share this with all of you today to share this with the incredible airport team who have really made this a reality and made where we are today come to fruition this is no pun intended a foundation of where we are at the airport this is the steel that's going up the structure, the ability for us to move in to the future and really take off with our projections of implements and passengers and the experience to welcome people to Vermont, to the city of Burlington and of course to this Burlington international airport so thank you all very much I think we're going to open it up to questions right now there's one thing Nick, your team and Mayor Weinberger's team important, I should mention John Tracy who's the head of our Vermont office who's here let's me forget what's needed for this and he is organized with our team of people and critics and everybody else to say how do we get this funding how do we make it work it is a team effort so thank you so what are we doing now? so I'd welcome any questions on the project anything for here what we're going to do after questions is we're actually going to invite everybody to sign this beautiful white beam this steel beam behind us which will be constructed into the project open to questions right now is there a timeline for filling the aviation director position permanently? the question is about filling the aviation director role permanently and it's something that I've been in consultation with the commission about and we all have a great deal of confidence in Nick's leadership and are focused on projects like this and getting the work done right now we've not set a timeline for a permanent search we will do a search before appointing a permanent director we haven't initiated that yet and don't have a timeline for it yet the groundbreaking or topping off was delayed twice did the progress of the rock? not at all so we started right on time right when our permits allowed us to start we made immense progress with the Jacobs, the Engelberg the Ireland teams to immediately move into this with the hopes of course with topping it off, wrapping it up for winter so we can get inside and do some of the interior work in fact one of the things I missed was there are changes inside the existing terminal that will occur because of this project like I said two checkpoints consolidated into one into this building which opens up the north end of our terminal building to new opportunities in the future all that's happening within the next 12 months so we are right on time are there going to be any changes to the control tower at any time? the FAA air traffic control tower there are not in our master plan there are thoughts of designing the terminal building to the north this is very very future forward thinking to connect to that building but the tower is not going to be impacted because of that I'm just curious what the demand for flights has been like as the pandemic rages on here I know in the summer there was likely a rebound with that as the state of Vermont reopened what are we seeing now with that it's really exciting it's higher than we expected it it's growing faster than we initially thought we are working with our incumbent airlines to make sure that they have the resources that they need to continue operating I'm happy to report that all of our routes are back online except for one we have mainline air service which is a larger aircraft that is now continuing their operation over to Chicago our percentages are climbing a little bit faster than we expected right now we are between 60 to 75% of our 2019 numbers which was a historical 10 year number for us but we are also looking at our revenues too what's happening on that side of things and we are even greater on our revenue there's been some tremendous effort again on the federal side to help all airports through the country through the pandemic because of those losses but the growth of the passengers the growth of the concessionaires here at the airport and the moving forward of each one of those entities lets us realize that we are a little bit higher than we expected I know every single flight I've taken the last few months it's been a lot of it everyone has been full which means we need more planes here yes, yes, yes why don't we do the ceremony pad and then I could be available for later


Hey everyone, welcome back to Nintendo Prime and oh you know when we're on this set we have a lot of news to talk about today five huge stories including potentially a new feature for Breath of the Wild 2 that includes clothing, durability, um yeah please Nintendo don't uh destroy my favorite clothes too quickly but uh before we get into that hey why don't you guys drop a subscribe we are on our road to 100 thousand subscribers so why not drop in and become a subscriber before we get there so you can say hey I was there I was part of the club before the club became I don't know three digits long I guess I don't know there's multiple digits of the more like what are we 77.8 hey we also have a massive giveaway event this summer called Prime Gaming Fest it also involves live reaction to Summer Game Fest uh giving away thousands of dollars with the stuff and you gotta be subscribed to win that stuff anyways so uh why not just get in now and so you're all ready to go for June all right that being said let's get into today's news and the first one deals with the potential of brand new Sega Genesis slash Master Drive games coming to Nintendo Switch and this is because the Twitter account NIN status update which is basically one that tracks you know maintenance for Nintendo Switch noted that there is direct maintenance happening to the Sega Genesis slash Master System uh you know network stuff at Nintendo coming up here on the 22nd and typically when we have such stuff happening they drop brand new games that same week and that same week would be this week so uh that's just something worth paying attention to because they've actually had this happen the last two big game drops and remember when they drop a bunch of games for the Sega Genesis slash Master System uh they do it like just rapid fire like here's 20 games so we could be seeing a massive drop based on maintenance that's happening tomorrow so pretty exciting our next story deals with Star Fox Zero because that is one of the Wii U games of course that hasn't actually come over to Switch yet and we know last September platinum games who actually were the developers of the game however Shiguro Miyamoto was actually the person running the team uh they you don't want to bring the game over they think it's worth bringing over they think it could get a better reception the second time around and obviously we've seen a lot of Wii U ports perform very very well on Nintendo Switch but they're not the only ones uh the the co-producer with Shiguro Miyamoto the art character creator Takaya Amura went to Twitter of all places which tells you he's already tried talking to the Nintendo privately not giving the response he hopes so he went to Twitter to essentially beg Nintendo to let Star Fox Zero get ported over to Switch here's what he had to say Dear Nintendo six years have passed since the release of Star Fox Zero today I think there are some issues but please port it to Switch also if you can produce a sequel to the animation because there was an animation that went along with the game back in the day we will also be in charge of scenarios and content I look forward to working with you best regards now typically if you're going to see something like this go to social media they're really just trying to garner a bunch of fan support for bringing the game over because Nintendo obviously has not responded or has shut down the idea of bringing this game over and I really hope Nintendo hasn't I would hate to see Star Fox Zero left to die on Wii U I understand that aspects of the game didn't really click with some people but some of those aspects could be cleaned up and modernized for Switch also it's the last you know decent Star Fox game we've had so well we all you know would love a new one it's one of those Star Fox is clearly sort of up in the air on if Nintendo is going to continue to support the IP so why not at least give us the Wii U and especially a platinum games is already willing to do it and probably willing to bring it over on the cheap so here's hoping that Shigeru Miyamoto and the rest of the Nintendo team are listening and that hopefully all of our fan reactions to this and our desires to get this game over end up reaching the right ears at Nintendo to make it happen. The Daemon X Makana team is added again Marvelous XC games they brought us at Daemon X Makana some people love the game some people didn't they're added again with a new game called DeadCraft which will be coming to Nintendo Switch and all platforms on May 19th they actually just announced this game today and let's just dive into the press release while you watch a little bit of gameplay here so DeadCraft is the newest deadly and daring game from Marvelous's first studio creators of Daemon X Makana as if a hail of meteors reducing earth to a barren wasteland wasn't bad enough the devastation released a mysterious virus that resurrected the dead ravaged by fire from the sky and the dead below only a fraction of the human population remains largely clustered in the small outpost where power hungry opportunists capitalize on the chaos a rare survivor of exposure to the virus part zombie Reed is captured by the twisted Nebron leader of the Ark after escaping from the torture table into the surrounding wasteland Reed is determined to return to the city and exact some apocalyptic justice stare in wild wonder as the half human half zombie protagonist Reed slices through foes on a quest for righteous vengeance wield his inhuman zombie powers defend off enemies while searching the wasteland for answers to what happened to the only man he could trust build fantastical new armaments conjure curious concoctions or even grow and harvest zombie soldiers to stand by Reed's side against whatever the apocalypse throws at him it's a dangerous world in order to stay alive read must take full advantage of the dead key features including farm the dead to stay alive plant fresh corpses or just a combination of limbs into the ground and give them a little TLC until they sprout into an undead army of infantry sentries and more creep test at crafting surviving the apocalypse sometimes means using whatever scraps one can find to make new weapons other times it means enlisting a loyal undead to assist in building and running an entire factory of grotesque machinery churning out an unholy amalgamation of survival items death defying powers of the undead Reed zombie side gives him a powerful advantage in a fight allowing him to shield himself from danger or swat enemies away like annoying gnats but as each devoured enemy pushes him closer to his zombie side he'll have to take care to maintain what little humanity he has left become a savior or a scourge help out the survivors to learn new recipes or abilities but if Reed's hard up for money or supplies shake down a local and take it off of them as long as he doesn't mind potentially becoming a wanted man now the game is going to be 24.99 for the standard version or there will be a digital x version for 39.99 and yeah pretty crazy we're getting this game there will be a free demo available a little bit later so you will be able to try out the game before you decide to plunge into it which i think a lot of people prefer we did get a demo for daemon x market so why not get a demo for this game as well so yeah may 19th not too long that's right around the corner so hey you know what try it out for free and i guess we'll see what happens today i'm finally happy to give you a real update on teenage mutant ninja turtles shredders revenge my lord we have not had a real update on this forever and first up boom here's some gameplay because ign has a bunch of brand new exclusive gameplay and hey it's always good to see new gameplay of a highly anticipated classic style beat them up ninja turtles game right like just saying that already you know it gives me a little bit of goosebumps but what's really cool about this game is that limited run games is actually going to be releasing a physical version of this game with a little bit of extra content now limited run games normally when they do this they do limited runs of games but they did know this time around this will not be a limited physical version they will be actually selling it in you know huge quantities on places like amazon and maybe a few other retailers so that's really good to note also the physical version unfortunately will not be their date one it will be releasing at a later date but we do have some release news update and we still don't have a release date for teenage mutant ninja turtles shredders revenge but we now have an updated release timing and the timing is this summer so yeah june july august summer in there we're going to be able to finally play this game also of note they did announce today that the entire 1980s well 87 i believe technically voice cast from the original cartoon series have reprised their roles for this game so that's obviously really really exciting for those of us that are classic fans of the old school ninja turtles like i am so i'm really looking forward to see where this game's gonna go we haven't had a game like this from the turtle series in quite some time that's actually been worthwhile so hopefully this one can live up to like the kawabunga collection coming out that contains all the classic beat them up ninja turtle games that we remember at least i remember from my childhood and for those of you that have never played one before you're really in for a treat now our final story deals with a brand new patent from nintendo filed by a very interesting person the original technical designer of breath of the wild actually filed this patent on behalf of nintendo and it deals with clothing and this patent is probably going to apply to a multitude of games at nintendo because it's not specifically you know going to be clothing durability per se however it that could be how you interpret parts of this patent that we'll get into so we might actually have some updates for breath of the wild too and how they're going to add durability to clothes i i think that's rather fascinating considering some of the some people love the weapon durability some people hated it now durability to the clothing that's going to be quite interesting if they go that route but what's really interesting of course is what this general patent means and first let's read nintendo life's interpretation of this patent so the recently filed patent is for a process called deformation this is something that stops clothing textures from seeping into an in-game character model so you know no awkward lack of cape swishing because it's blending into mario's thigh or something and no accidental exposed skin in wintry areas we won't like to get cold in the hebro region would we in the image above you can see a very faint outline of clothing on the character model on the left ch1 this is way too close which would lead to the kind of stitching you wouldn't expect on a person we imagine this is a particular pain for floaty clothes like skirts this is what a model might look like before deformation the table underneath the two figures indicates everything stored by the game's dynamic random access memory or d-ram and you'll see that clothing data is stored there too the character on the right ch2 however is the lucky one no risk of getting a chill because of exposed skin as the character model has been made smaller and the clothes are now an extra layer previously devs would have had to make a brand new model to fit the clothes they want to don so this is just like putting a jumper over your clothes uh this patent has actually sparked some confusion among fans however as the patent was filed by zelda breath of the wilds technology supervisor tukahiro dota who we assume is also working on the elusive sequel which has got some speculating that breath of the wild two will have armor durability as well as weapon durability now segment next an independent website from nintendo life actually is the one that does a lot of the notations on the fact that this could mean things like clothing durability and in breath of the wild two as well as obviously making it so the clothing isn't clipping through the character and actually looks more natural they say the patented clothing is believed to incorporate durability mechanics meaning that any armor that plays wear that players wear in breath of the wild two will have a limited number of uses the armor will hence need to be either replaced or even perhaps repaired and failing to do so will render them useless if such a new clothing durability mechanic becomes part of the sequel players will be forced to keep looking for new armor sets or take constant care of their existing wares now we'll also add a new twist to how players tend to stick with the best armor in the game once they have found it and i do find this to be a rather interesting and almost natural addition to breath of the wild two we already have weapon durability why wouldn't you have clothing durability that you know when you're getting slashed out by enemies and lit on fire and you know dealing with the elements so your clothing is going to break down and we've actually seen link with his armor and and the sword and everything look like he's wearing tattered clothing as is now while that could be a clothing option in the game it could actually be already showing off the clothing durability mechanic where the clothing does become more tattered as you wear it and then obviously maybe you could repair it at a tailor or you know by gathering certain materials like we hope you can do a weapons as well we kind of hope that this is a new addition it brings in it to the game in terms of hey keep the durability that's fine it kind of forces us to use a wide range of weapons but also allow us to repair our favorite weapons and also allow us to repair our favorite armor and clothing so it also means that you might be able to find multiple pieces of various clothing in the game so i find that to be really cool as well weapon durability you know if you already have that why not have armor durability and obviously you know the the effect that this pack can have on all of nintendo's games is just really really good it's going to make it seem a lot more natural and not like we just took the mario texture and just repainted his skin and then you see really clipping and the clothing doesn't look like it fits right so this is going to affect multiple games but still if durability comes to breath of wild too you guys know i'm all about that so thank you guys so much for tuning in i am the fan of rebel jets from the center probably sure to let me know what you think about this video down in the comments below about all the news all this crazy shenanigans about maybe prime gaming fest and the few times i've hinted at it to this point and you know what i'm going to catch you guys probably on a live stream tonight since we didn't stream yesterday due to the buck's playoff game uh so we'll be probably streaming tonight and uh you're going to see why making this video the way that i'm making this video you're going to learn tonight that uh this wasn't exactly the most uh pain-free experience all right catch you guys in the next video


Hey yo, what's up, bro. Is that Sonic twerking? Uh, no. Alright, whatever. Dude, did you get the email? Wait, what are you talking about? He sent us another video from the dark web, bro. What do you mean? Alright, let's check it out, man. Okay, cool. Look it up. Look at it right now, go. Oh, hey yo, bro. It's already on my desktop. What the heck? Let's open it. Do not open, bro. Do not open? Okay, dude, that's the one. That's the one. Sonic EXE? What the? Oh, hey, now, bro. This is cursed, dawg. Go, go, open it, bro. Hello. Oh, do you want to play with me?  Oh, no. What? Do what I'm saying. Bro, he just said we're gonna die. What? Mikey, what? Wait, where did Mikey go? What? Mikey? What the heck? Hey, yo, what?  What the heck? Mikey, is that you, bro? Oh, no. Ready for round two.


So, why prostate MRI as opposed to say ultrasound or digital examination or serum PSA? First of all, serum PSA has a sensitivity of 36 percent for diagnosing prostate cancer. That just frankly is not good enough. Digital rectal examination is somewhere far south of that. And in terms of assessing tumors, we use histologic rating called the Gleason score. We'll talk about that at a separate time, but a Gleason score of seven or over is considered more aggressive, six or less, less aggressive, and that'll be a story for another section. Previously we used transurethral rectal ultrasound to biopsy and define aggressiveness of the Gleason with the histologic Gleason score. But those biopsies were not directed to any one specific ominous locus. They are somewhat random in character until MRI came along. So what are the indications for MRI? Probably the most important indication is surveillance in a low risk tier one individual. So what does a tier one mean? That is a separate vignette coming right up, but we're going to have three tiers of aggressiveness and risk. There'll be tier one, tier two, and tier three. Then we also can use MRI for staging. And the staging will help us identify not only how big the tumor is, but also it's histologic character because there's a correlation between the Gleason score and the appearance on MRI. Now let's go back to surveillance for a minute. Surveillance is used in tier one low risk individuals. So what does that give you? Well, if you can survey the prostate gland and assure that there's not an aggressive lesion and use a conservative method for following the gland, you avert the potential complications of intervention on the prostate gland with all the techniques that are available out there, starting with surgery. With surgery, the risk of having some ejaculatory dysfunction is as high as 60%. The risk of incontinence or leaking is as high as 30%. So if you don't need a procedure for an aggressive lesion, you shouldn't have one. And in the past, we have been operating on cancers that are less aggressive. So we've got surveillance, which can prevent you from having an unnecessary procedure, probably the most important indication of MRI by far, and then second is staging. And staging helps you not only decide the character of the tumor, but also what to do. Because if the stage is later stage, that's a different treatment than if it's early stage, even if they are both aggressive. So we've already talked about avoiding unnecessary surgery, let's take the converse. You've got somebody with a rising PSA and we know that the PSA goes up with age because the normal gland gets bigger, more normal gland, more PSA. So it may be a matter of how fast it rises, but the converse that we're referring to is what if the PSA is rising and there really is an aggressive cancer? How good is MRI at picking up Gleason 8s, 9s, and 10s? Really, really good. How good is it at picking up Gleason 1s, 2s, 3s, 4s, 5s? Not so good. And that's a good thing. Because we're not picking up or not registering a lot of these smaller or less aggressive cancers that should be surveyed for conversion to more aggressive character, which MR does really, really well. MR is used for biopsy, planning, and overlay. So instead of going into a gland, going through the rectum from the back here, and just randomly putting a needle in and saying, okay, I'll take 12 samples, one here, one here, one here, and so on, with MRI, you have directed access to that nodule. You overlay it on the ultrasound using it as a map and you can go directly to that locus and put your needle right where you see the abnormality. And the MR far more accurately shows you these loci than ultrasound ever could. So you have this very nice correlation between MR, truce, and where your needle should go. On top of that, you can take three-dimensional MRI, 3D MRI within sections, and you can volumetrically take a nodule, and then on a series of axial slices, you can simply trace the outside of the nodule from one slice to the next and get a volume of tumor and further assist the accuracy of that trans-urethral biopsy done under sonographic biopsy. The other thing you can use MRI for is recurrence. MR does pretty well in patients that have had prior partial treatments, including subtotal prostatectomies, prostatectomies, which is a more complete treatment, but many of the other treatments that include laser, heat ablation, extra corporation, and other newer techniques that alter the architecture of the prostate, but there are methods to assess tumor recurrence that we'll discuss at a separate date. So we've got surveillance is probably the most important aspect of MRI that's unique. The second most important is directing trans-urethral ultrasonographic biopsy. Probably the third most important is staging, and all of these combined will allow you to avoid unnecessary surgery or intervene if you need to intervene if you've got the landmark correlate of Eglison 8, 9, or 10, and we'll discuss what that correlate is. We also said that we're going to survey individuals that have Tier 1 disease or lower grade types of disease. There'll be three tiers, and we're going to discuss those tiers in a separate section.