This study found that closing schools can reduce the number of COVID-19 cases in a community. However, this comes at a cost of learning loss and well-being for students and their families. This article was authored by Abdul Mughid, Rezia Ali-Anni, Mujahid Abdullah, and others.


My name is Ed Doherty and I'm the Precision Machining Instructor for Suncoast Technical College. While all the students are, I like to call them apprentices, it's a career and a year. That's our motto here and we try to train everybody to work in the modern metalworking industry and we get them trained in just under a year, about 11 months, and we've had a hundred percent placement. I really can't fill all the jobs that people ask me to fill. So we have a lot of need in the area for machinists and computer integrated manufacturing. Today's world has a lot of computer driven machines, so you need traditional machining skills and also to be able to work with computerized programming and put those skills together in order to make high tech modern parts for like the plastics industry, medical implants, surgical tooling and the defense and aerospace. Our current class is all adults so it's a full day. We come in at 7.45, everybody punches in on a time clock just like they would at work so they become responsible employees and we'll go through some preparation for the day and we'll do some technical training and then we'll go into the shop and start working on projects and sometimes it'll be individual projects so they'll team up and work together on some collaborations and we're also working with our drafting department to, they'll design something and we'll make it and we'll work together on how that all works. It can be, you know, if you want to talk to me directly, the student services will have, leave information, I can call you back directly and we can talk together, you can take a tour at any time, they even have a blog and a YouTube channel so people want to see exactly what goes on and you know, without having to come in and the projects we work on, I have that also. So if they call me, I can send you that information and you can also check it out, you know, on the internet.


15 days in quarantine and I'm out tomorrow Opposite I guess it's like I don't know if you can see it, but it says concept street house Some rooftop bar. That's kind of cool, huh?  I'm not gonna drink it. Why do I need a bottle? Day 14 of quarantine. I'm officially out tomorrow. And yeah, this is a bathrobe, but I've run out of clean clothes and What are you gonna do? All I need now is a cigar and I feel proper pimping So this video is gonna be a day in a life out of quarantine the first day out of quarantine Something like that. All right one more sleep. See you tomorrow 7 a.m. Today is the day Then I'm out before we think about the day ahead. I have a meeting at 8 30 Okay done with the meeting and now I need to check out and head to the next hotel check into the hotel I like this place. This is just temporary. I'm still gonna find an apartment and maybe they will do a video of that so this hotel actually offers a laundry service and that's perfect because I've run out of clean clothes and I Really need some clean underwear could just go in commandos.  What's this? There's a drawer now. I need to go to the bank to get some money because New country new currency for the grab some coffee in the local area need that healthy dose of Vietnamese coffee Then get a little trim. I'm still figuring out what I should eat and where I should get lunch I don't know 14 days of not choosing what to eat. Now you've got to choose.  There's a few people ready about the sea. So that's cool.  I forgot how noisy it was in Ho Chi Minh like it's pretty interesting Lots things going on.  So so much better. Sup, man. Yeah, basically My what's burning like I've always wanted to live there.  Why is it so hot anyway? Kind of drunk It's like 1 1 30 pretty early night, but this is what a day looks like out of quarantine All right, peace out


Hello, welcome to theCUBE. We are live here in Las Vegas with SAS. Innovate 2024, I'm John Furrier, your host of theCUBE with Dave Vellante, Rob Streche, a CUBE analyst at theCUBE Research. It's two days of wall-to-wall coverage of the show Innovate here. We are rocking and rolling. Are you doing, boys? Dave, keynote review. Rob, great to see you. Good day. So we got in yesterday, got in early. Rob, we got in early. Dave got in right in time for all the action. During the partner sessions yesterday, we had a good chance to talk to some of the folks, and the keynote at this point we just came back from. So we look at the keynote, we're going to analyze that, but also look at what's happened in the ecosystem here. Their partners and customers are all here, and they're seeing real progress. The Dr. Goodnight gave a demo, he's a legend, actually referenced his first line of code in 1980. This is a private company, Dave. We were here last year. Rob, they have a lot of data. They have an install base. They got a lot of customers in all the industry verticals, and GenAi, as we said last year, was a gift to these guys, because it gives them a new opportunity to essentially go to the next level on the interface side and leverage the data with their customers. Yeah. I think that one of the most powerful comments that we talk about a lot here on theCUBE is that garbage in, garbage out. And the whole purpose of SAS is to get the data right. And I think everybody talks about GenAi, because it's the new shiny thing, but they've been doing AI using the modeling techniques within SAS. All the way back, I did it 30 years. Yeah, I was going to say, I was a SAS programmer 30 years ago. That's what we were talking about. It was SAS, a little bit of SPSS, but there was no R back then. You were a SAS coder. Yeah, yeah, I mean. We have a SAS coder in the semi-colon. You know, I love the semi-colon because everything ended in a semi-colon. And in fact, they have a really great sticker. Here that my love language ends in a semi-colon, which is kind of the winky-eye thing. So it's funny. All right, so it's good to have you have that DNA. Dave, you're looking at the marketplace. Again, this is a private company and they could go public, but Dr. Goodwright, they go public, stay private. They've sort of threatened it before and I think they will eventually go public, but they're about a $3.2 billion company. They've been around since the mid to late 1970s, okay? So they've had to navigate through a lot of different waves. I mean, they came in at the mainframe era. They had to go through the client server era. They had to deal with the PC era. And then, you know, then cloud, that's what Vi is all about, is their cloud native platform. And now they're injecting Gen AI into virtually everything. And of course they compete with the likes of Databricks and, you know, the big hyperscalers. Snowflake is kind of catching up to that whole. They also had them on the partner list too. Yeah, so they do partner with them. Absolutely. There's a little competition there. Let's get into the key now. I'll get your reaction on Dave. You were tweeting feverly. Rob, you were some tweets up there. The topic here is future of data and AI. That's the theme. I love the chart data plus AI plus decision plus outcomes equals learning rate. And I like how they added learning rates. So it's just not about outcomes. They're in the left-hand side of the equation. The equal sign is learning rate. So one learnings, but the rate words implies acceleration movement that it's never done. It's always generating. And with this new category of gender of AI, it's a huge part of the equation. So a nice subtle point there. The other thing I noticed is that they now have the three pillars locked and loaded. Productivity, performance, and trust. I was just talking with Reggie who handled that whole trust department. He'll be on theCUBE. Huge part of it. Obviously via workbench. And the big news is that they're introducing SAS models.  They're going to have selling Lego blocks of models. That's my word, not theirs. And to me, what was most impressive that I liked that was kind of like squinting through kind of the dots that were connecting is they had this concept of stored prompts. Okay, which I thought was an excellent illustration of where this is going. It's not just about generating an outcome and response, prompt return, answer, question. It's consistently solving the quality problem. So I think what we see with stored prompts, Rob, is that directional power law specialty models that we published over a year ago coming to fruition. And the value is going to be in using other things, stored prompts, either other modules to make the data better so that the ultimate decision and the response, whether it's reasoning or an outcome, is key. This is a key point. Yeah, I think where it really goes to is their persona that they've always been really tight with is the data science crew. And I think you develop in SaaS, I thought what was nice is they talked about Python and are coming soon. And I think that gets across all of the people in the data science community that really want to do these things and do them at a level that helps drive these models. And I think the key to their models are, it's some of their IP in those models. So it's not like you have to understand or worry about where it came from. And I think that's part of the trust and the governance that they're really looking to help organizations do. What Brian Harris was saying, he said he used the example of we go to a meeting and there's a lot of dumb questions in the meeting. So if you can map your questions into sort of multiple stored governed answers, we can give you not only better answers, we can give you better questions to get to better answers. So that was kind of interesting. And the other thing that I want to ask Brian about when he comes on is and nobody's really doing this today. I think Databricks is hinting at it. Amazon's hinting at a little bit is being able to dynamically not choose models, not like the model garden, that's one thing, but actually to have the system dynamically choose the model for you. I know for instance, Amazon retail, their supply chain, they use different models for different parts of the supply chain, but nobody has figured out, and maybe you've got some visibility on this, how to dynamically actually execute models for the specific use case or even parts of that workflow. That is going to be I think the next big thing beyond the stored governed discussion that we had today to improve the quality of the problem. I think to that point, there are a lot of people saying, hey, we'll make it easy for you to switch models, but you still need to do that testing and data quality. And I think the big message around synthetic data and how they're helping create that synthetic data or using Gen AI to create synthetic images like George Pacific was on stage with these odd looking trees that they acknowledge were odd looking trees, but again, looking at how you create cases where you can train data on safe data that is capable of getting to the answers repeatedly. And I think we always have heard that about the data quality.  I think that was kind of under the covers for the whole thing. I mean, they had the package and then they had the four areas, Gen AI, co-pilot, data maker, which is a synthetic piece, and then the workbench, all that working together. And I like how they ended it, Dave. They said the future of data science development, that's how they're positioning as AI powered developers with a little red cube, where the blue cube, good to see the cube out there. But I like how they're positioning that. I want to get you guys reaction to that because my takeaway was, wow, the future of data science development. Interesting choice of words, guys, because we've been seeing in the cube that the data science world is shrinking in the sense of, in terms of core people, you don't have to be a data scientist. You don't have to be in the game with Gen AI. You can be a user. And the democratization way that's coming in, Rob, is very clear in the data. And I know we got some research going on there, the cube research on this point, but we're seeing the trend being, okay, data scientists, you don't have to have all these data science in where you have a bunch, but you can now have real people doing data. And I think this plays into SAS's hand, but they're saying this is the future of data science development. What about just data in general? Now the title of the show is the future of data in AI. So I think what I wanted to see more of from SAS was the democratization angle. I think obviously everyone in the room is a data scientist pretty much in the SAS category. So what's your reaction to that, guys? Is this just playing to the crowd or is that? I thought they got at some of that, right? With the productivity, with the Viya co-pilot and where they were going and enabling people to build their own chatbots basically into there and actually add their data into the Viya co-pilot and workbench co-pilot so that they can be more productive. Because I think it is a productivity issue. And I think it's, again, having been on that side and done coding in there, it's fairly straightforward if you understand heavy data science and how all the algorithms work. And then, okay, so to your point, pick a model. So here suggest me some models. It suggests some models. You can switch in between models. I thought they were going to go and say, okay, now combine those two models. When they looked at CO2 emissions across the entire US and different cities, I think there's still places they can go. And I think they will go with this to make it easier for data scientists because I think it is such a finite resource. What do you think? Here's the way I think about it.  You know, we're not really match reducing anymore. And you remember Data Lakes? Well, you know. I was going to throw in, hey, about the mark.  But then applying it, it actually has to be evolutionary. You can't just, you know, overnight apply this stuff and drive your business.  I mean, we've been doing that for decades, right? But the way I think about it is it just keeps getting better and better and better. So we're getting more intelligent with all this AI. People are afraid that it's going to, you know, we're going to lose jobs. And yeah, that may happen, but I don't think anybody's going to like tap this AI and then say, oh, I want to go back to the way it used to be. I want to be dumber. That doesn't happen. So I think what you're seeing is this, this really progressive evolution of technology, but it's always the people to process the business models that are the blockers to integrating and it takes some time to do that. And then once it's absorbed, everything gets better. And nobody ever wants to go back. Well, I think that's a great point, but I would also add that, I think they get a lift from Gen AI because the interface modernization of Gen AI gives SaaS an opportunity, Rob, to take the best of what they built their legacy business on and put a front end on it. That's not just a fresh coat of paint. I mean, it's a new categorical category of user interface. User expectations. The generative, we heard Jensen Wong say this in a video when we had our chat with him. We heard it from this morning from Georgia Pacific. Basically, I don't know if you caught this. He said, yeah, we do a lot of stuff in SageMaker. Okay, because a lot of AI can be done with things like SageMaker. But what they're doing with the Gen AI is they're making it an orchestrator, right? To your exact point, John, it's the interface now that's simplified and, of course, becomes natural language. So it's a combination of legacy AI, if I can use that term, and Gen AI being the new abstraction layer. Well, I mean, Gen AI is generating, okay? Other AI was part of subsystems, machine learning, other ops. And Rob, this is really weird. But you're not going to throw that stuff away. In fact, if you add the stored prompts to it, I mean, everything gets better for the worker. In this case, the data scientist or the developer or anyone who's managing data. So as Gen AI and the interface comes in, this is where I think they miss the democratization angle. Maybe they're going to add it on the next year or whatever. But when they bolt on that user interface change, you don't have to be a data scientist. You can extract away all the other stuff with stored prompts. You're going to have stored stuff. I think you still need some data. At the data quality level, you still need data scientists. And I think it'll be not exactly that persona going away, but to your point, I think when you're doing model evolution and you understand what the output needs to look like, maybe you can have people with less data science skill, people who are newer to the industry. So to your point about democratization, it's an interesting point you're bringing up, but do you think about the market? I'd love to get your thoughts on this. You look at Microsoft, which I would say, I would position Microsoft and I'm overstating it, but they got the one model to rule them all. It's the open AI approach. And so what they're trying to own is the low code kind of no code space. And so I almost think it was maybe by design because that's maybe too simple. Not that these guys can't do no code and low code and Google, you guys were just Google next, you saw a lot of that, but there's still a lot of like serious coding that you can do and these co-pilots can make these data scientists smarter, take away some of the heavy lifting and do some things that you're not going to be able to do with low code and no code. What do you think about that? I think it's time to value of the data who's going to accelerate. And I think from that perspective, it's democratizing the data and getting it into the right places at the right time faster. And I think also the quality of the data should improve assuming that you're training the models properly. And I think that's where they were talking about is that iteration process. So I think, again, the data engineering part of it, the data science part of it, still needs to be there when you get to the algorithmic aspect of it. But I think, again, you'll have other people involved in those pipelines. I mean, to me, there's no doubt in my mind that the benefits of the under the infrastructures there is going to be a lot of AI. In security, we have the thing, security for AI and AI for security. The same thing goes for in industries like this. You've got AI for SaaS and AI for SaaS infrastructure. And if you look at Georgia Pacific and the examples they had with how they're using the use cases. And again, Brian Harris had real meat on the bone, real use case production. He called up production workloads and all those were based upon Amazon infrastructure web services. So again, back to who wins here. Amazon's got the models, but they're running infrastructure. On top of that, the SaaS has the intelligent decision engine or whatever they called it, that next layer up. That's their core layer. And the next layer on top of those modules, real time data, knowledge bank and process models. And then the GNI layer on top. And then the interface on the top. This is kind of a real world production workload running in the AI stack. So I think to me, that's all SaaS. There's nothing to do with open AI or Anthropic. They might use some stuff within Amazon in VPC, but Rob, this is a use case. I thought it was a fantastic stack for them to show off and being able to see that to your point, the intelligent decisioning is really important. And that's where that QC comes in, in that entire stack. Once you've actually deployed the models. And I think they talked about it at the edge. They talked about it from an inference, how fast, especially for Georgia Pacific, they need to be able to make these decisions when they're flying drones over fields where they're trying to harvest stuff. I thought that was a really good understanding of how they were using lightweight models at the edge for inference.  Now the challenge for a company like SaaS that's been around for 40 plus years is they got the old stuff and they got to balance the transition to the new stuff. It's just the way the business is. Dell has to deal with this, HPE has to deal with this, IBM has to deal with this. But they're dealing with their own stuff, right? So like when they abstract it with any kind of old SaaS legacy called code or whatever interface, it doesn't really matter if you don't see it. It's still fast. So I think this is the opportunity that Dell has. And we're talking to Dell about that. You can have all your stuff under the covers and the interface is here. And I think that to me was the big aha because what matters is the data, the code. So they say, okay, we want some Gen AI, let's do it. Now, what was interesting here on that point to take it to the next level is we've been saying on theCUBE on our last podcast, we went in deep on this. I did this on my NYSE report. The question is, do you build your own AI or do you use AI? Now there was an interesting point in the presentation by Brian Harris, the CTO, where he called out the industry perspective, said there are buyers, builders of AI, and then there's buyers of solutions. And then he said subscribers of models. So a little bit different twist on our thinking of you can use AI and then build your own or not. And sometimes you don't need to build your own AI. And he called out industries that need to do that like pharma, drug discovery, and some don't need it. Some just can use this lose. So I think they're on point there. And then this idea of subscribing to models, the first time I've seen that from an enterprise player, we've seen it with Open AI with their little model marketplace. But this idea that they're going to have baked models is a pretty genius move in mind. So I want to make a nuanced point. I've even wrong about this, but I don't think I am. It's not just putting a veneer on sort of the legacy products. Like we saw so often we saw cloud washing. People would take their on-prem stack, they'd wrap it in Kubernetes and stick it in the cloud and host it in the cloud essentially and say, oh yeah, we got cloud. They built a cloud native platform with Viya. It goes back to probably 2016, 2017, I want to say. So they're building their AI stack on top of that modern cloud native platform. So that's to me an advantage. To me, the example I would use would be like MongoDB Atlas. That's a new stack that was cloud native. And so a lot of companies, they'll just kind of frankly have half asset and through a little wrapper. So that's my sense is that these guys are doing true organic innovation. It's called SAS Innovate. So they are innovating. And there was a lot of good announcements today. We're going to hear more in a moment. I think to that point though, like the speed at which Workbench came up and that you could pick how many cores you could even put in GPUs. They're speaking platform engineering and abstracting that away because data scientists don't want to think about that stuff. And I think so really they did it in a really, I thought it was a really slick way that they're doing their cloud platform and making it easy for people who are used to using Workbench locally to come up and use it through the browser. And how about Brian's quantum wrap? I mean, that was kind of interesting that he spent so much time there. I mean, I remember last year at Cisco Live, you were sort of like surprised that Liz Santone, he spent so much time on quantum, but he said it's one to two years away from their gen AI moment. Well, we know that NVIDIA was poo-pooing quantum. We're going to ask Brian about that. I'm going to pull the quote from Jen's speech. Yeah, I mean, I think that the quantum, I mean, it's a science project that has use cases in areas of production. That's opportunity. The rest of it's all kind of there. Now, one of the opportunities that's networking is a big one. Photonics areas is a challenge. So I think the networking of quantum is going to be a problem, but there's going to be use cases. I'm not as bullish on quantum as others are as you know. I thought what he said though was interesting because he was talking about also hybrid models and using classical computing and quantum computing to actually get at different insights, which I think is probably where we, they're probably at the pointy end of the sphere based on what the personas are who view SAS over the years. They're at these companies, deep research, super data science people who are probably tapping into some of the quantum techniques that are out there. We were at IBM last November at the Thomas Watson Research Center and of course IBM's deep into quantum. We got the tour and I'm not an expert there, but there were several analysts that were really deep into this stuff. And what I learned was there's like six or seven and maybe even 10 sort of competing philosophies on how to do quantum and everyone has its benefits and everyone has its trade-offs. Some use a ton of energy, some are really expensive, some aren't that accurate or aren't that stable because the qubits croak. And so I think maybe you're right, John, one to two years I thought was quite aggressive. Well, I think what's impressive about this keynote and we're going to unpack it more at their media conference now we're going to go to and our interviews is that you see the consumer side of it with the chips, the hyperscancer, all the buyers of the GPUs and products. The enterprise has always been kind of like where's the beef on the enterprise and what you're seeing it is things like retrieval augmentation generation or RAG and things where customers have their own data. And I think what we're seeing here is with SaaS they have such a great install base and what they're showing and bringing to the table is the fact that you're seeing enterprise use cases right now where they can manage their data just like retrieval augmentation generation, you can do some RAG, you learn about prompting. That's all with your own data. And again, I think this is going to propel the power law that we've been talking about. You'll see a lot more use cases where it's my proprietary workflows, my proprietary data and enterprise using generative AI and building, mixing, matching that. So that's going to be very interesting. It's like a hybrid build by and subscribe model, Rob. So we'll be going to watch that. We'll add that to our repertoire and our research. Of course, we've got two days of wall-to-wall coverage. I'm John Furrier with theCUBE with Dave Vellante and Rob Stretcher kicking off day one of SaaS Innovate 24. We'll be right back after this break.


once again to another edition of the Red Brown and Williams real estate show. I'm Shannon Deskins along with Jennifer Brown Day and we can say now I think all schools are out and summer has begun. Summer is officially here you're in pool time and people out in the yard and kids playing in the neighborhoods almost every single neighborhood that we drive into right now for a showing. You see kids out on bikes or you can hear them in the pool so it definitely is summer. It's a time when number one a lot of people's houses are feeling pretty small so those people may be looking to purchase something new and bigger but it's also a time with school out being colleges and universities a lot of the rentals are coming open so if you've been in the market to maybe find a new place to rent right now might be the time to do that and I think you'll talk about later in your real estate minute but right now you brought five listings that are for sale. Yes absolutely and we'll start with the first one being a brand new listing in the Shelbyanna area. Yes this one is at Schoolhouse Lane and this is a brand new listing and I love talking about this listing because like I told you I actually sold this house to them years ago and they have now kind of outgrown it and they're looking for more of their forever home so this was their starter home and it's perfect for that and I'm just looking at the the exterior picture of that house I mean it's looking look at the views you're actually up on the hill with this one right? You are and this is one we didn't include the picture but I highly recommend you go on our website and look at the pictures I bought a picture that's actually off the back deck and it's complete privacy and it's a completely beautiful view so something that you really do need to see. Two bedrooms one bathroom then you've got a two car detached carport. Yes the good thing about this house you have two additional rooms that are not counted as bedrooms that you could easily transform into bedrooms or use as an office you have a lot of extra space to play with so technically right now it is a two bedroom could very very very easily become a three bedroom with minimal work and so it's one that you can definitely grow in it's not a small house it's almost 1600 square feet. Wow so when you say a two bedroom a lot of times people think that it might be very compact that is not this house this house has huge rooms and this also has you know not very interesting this time of year but it does have a brick fireplace but just give it a few months and that is going to be very very appealing but it's got an open layout like you said almost 1600 square feet so much bigger on the inside this is one of those you probably need to schedule a showing just to walk through. You really do because of how it lays out on the lot when you drive by it you really can only see a small portion of the house so if you are interested in that area if this looks like something that you want to see this really is one that you need to go in. And then we also need to add it has a fenced yard so it's got everything on the inside the fenced yard like you said you've got a small family small children pets this one is just waiting for a family to move into and call it theirs. Yes absolutely it is and this is your listing again let the price on this one $1199 so not a bad price for everything you're getting just outside the Pikeville City limits at Shelby Anna so if they want to take a look at this one how can they get a hold of you let's talk about that Pikeville office number. Let's call the Pikeville office at<PHONE_NUMBER>. Okay now the next one actually all of these are your listings today but the next next one is interesting because when you sent it to me it was a brand new listing now it is already pending. Yes so we're still going to talk about it you never know what's going to happen right but yes it has already gone pending on the market which means we've had an offer that's been accepted on it so if you're interested in a property that just goes to show you you need to act fast you never know which ones are really going to hit the market and go quickly. And this one is on Amba Street now this is downtown Pikeville kind of on the Hill area close to Mount Martha Drive. Yes you're not going very far up the hill this is really on the bottom of the hill closer to Hambly and but you're right there off Hambly you're within again walking distance to school shopping all the downtown area so a really really good location. This also has below grade square footage so they have actually finished out basement space so you've got above grade almost 1500 but total you're gonna have almost 2000 square feet if you include the basement. You can't really sit on the fence very long when it comes to real estate you just never know when that one buyer and all it takes is one buyer. Exactly. To come in and and if you're looking at it mess your dreams up. There you go. Well and you have to keep in mind typically this area is a 6 to 12 month market. We are a fairly slow-moving market that's just the way that a more rural market works but you do have the houses especially in the downtown area that are going to move very quickly because they don't come up a lot especially when you have one that's more moving ready priced well it's not gonna last long. Right now if you want to look this one up and follow this one on the on the website it's one one two two four nine that's the MLS number you can look it up on look at any of these listings up on the website when the listings up on your screen that MLS number will be right there on your screen. Now the next one is a brand new listing this one has not gone pending yet. You still have a chance on. Yes and this one's really cool we don't have a lot of duplexes in Parkfield so always get excited when we get to do something just a little bit different this is actually a duplex so this is one like we said you can live in part rent out part help pay your mortgage or it can be a complete investment property you can go ahead and rent out both sides and the way this was done this actually used to be a single family residential home so if you wanted to take it back there that's also an option and I love being able to say this is a house that can help you pay help pay your mortgage anytime that you can pay your mortgage and buy a house at the same time that's a win-win situation and this is on Town Mountain Road on Mays Branch in a great location because you're still in the city limits of Pifal. Yes and this is a great location like you said because you're still in the city limits but you're out far enough this is gonna be that more country feel so you're gonna sit on your front porch you might see three cars pass the entire day it's gonna be a whole lot more quiet but again you are within a you know rock throws distance of the school and downtown area right now this is one let's talk about the two different units the first one is not right under 950 square feet you've got one bedroom to or one bathroom and two bedrooms the other one just a little bit smaller with one bedroom and one bathroom correct so two different options for sizes yeah two different options that it actually does have a one car carport and that's on the side of the larger unit so that's something that can go with that larger unit and it does already come with a tenant if somebody is interested in keeping the tenant there the smaller unit does currently have a tenant in it deck space it's got private yard again this is just something definitely something to look at especially if you want to help pay in that mortgage absolutely and again just because it's two units now as you said it was originally built as one so it can be converted back so this is one of those that really has a lot of options it really does so anything that you're interested in that's one to look at and it's on maze branch again I'm assuming you've got a sign in the yard somebody can do a drive through a drive by on that one but it's priced well 149 nine to get two separate units that you can rent or like you said live in one for under 150,000 that's one that may not last long as well so let's give your email address okay the email is jay brown at rbnw.com okay now the next listing we're going to talk about is out of the city limits quite a ways this one's at mouth card but we've talked about this one before and I really like this listing yes this is a really really cute house really nice very very spacious and the reason I wanted to bring it back up is they have reduced the price on it so we want to make sure that everybody in that area is aware aware that it's been reduced and that it's available and I just glanced at the price wow it is reduced so everything we're going to tell you a hundred and sixteen thousand dollars and so you're getting a whole lot of things you're getting above grade square footage almost 1800 with another 1500 below grade so ton of space in this house yes absolutely and this is one technically we've got it listed I believe is a four-bedroom this is one that they have added on to they actually finished out space so this could easily again you've got a five bedroom home you just have one of them that doesn't have a closet no big deal so if you need the extra bedroom space it also has a living room a family room with a fireplace and then like you said you have all the basement space that is unfinished but is great storage or one day could easily be finished out for additional living space and that's a lot of people like to come into a place that's got unfinished space because they can put their own style their own touch to that so they can look at it and see that is it's just a blank canvas exactly and speaking of blank canvases when they bought this house there was a house an older house next door on the lot that has since been torn down and the lot is being sold with the house so you have an additional lot next door that is a complete blank space that they've got a little garden on but there used to be a house on it so it's large enough for another house if you have a family member you want to do a double wide or something like that and put it in next you've got that coming with this property so this and then this has a lot of updates as well you know a new kitchen countertops and a bar a newer heat pump a newer master suite so this is one of those if you live in that area or you don't mind a little bit of a commute into the Pikeville area I would definitely look at this because everything you're getting again $116,000 it's a really really especially if you look at dollar amount per square foot you're really getting a lot with this listing and this one I'm assuming another one with the sign in the yard absolutely all right this is out of the Pikeville office this is Jennifer's listing so let's give that Pikeville office number that number is<PHONE_NUMBER> all right now we're gonna end the show with another one that we've talked about before but this one has just been reduced this one has also been reduced and this is back in the Pikeville city limits you are over in on Meadowview Lane which is right at the bottom of Quail Ridge and right off Thompson Road the Walmart area so super convenient location this one is really close to let's say tractor supply Buffalo Wild Wings in that area going toward the polydition and kill addition right on the other side of the railroad tracks so it's convenient and it's in one of the more popular neighborhoods in Pikeville yes absolutely and this is one you're looking at almost 2,500 square feet not counting finished attic space and that is currently is completely finished in a playroom so additional space that's not on there three car attached garage and you're sitting on a double lot so you have a really nice yard space and then inside again four bed rooms two and a half bathrooms so you just have space everywhere it's just everything gives you a lot of room and this is one that you just love that white kitchen especially during the summertime and warmer months it seems like it just is part of that the the warmer season where you just want to get outside and enjoy things well you can bring that inside to this kitchen love that island yes absolutely and they did granite countertops in their newer plants is all that has been updated and this is one this is more of an executive style home so you've got that very comfortable den area but then you also have a formal living room formal dining area so it's just one it's a great family home this is one you can definitely grow into and it's got your second story but then it's got that open foyer so you're gonna walk in it's got that grand entrance feel with the two-story foyer and then you're gonna see everything else this house has to offer so and then again if you've looked at it before it may have been borderline out of your price range they have decided to reduce that price so I take it they're motivated sellers absolutely all right so they are wanting to sell this one they've reduced the price 384.9 is the price on this one now so everything that we've talked about today of course when it's up on the screen you see that little MLS number for this one is 111 459 you can look those up on the website or you can browse through the website is great it's a new website and you can search for any house land rentals commercial anything you want on rbnw.com absolutely we invite you to go on there and look like she said it includes everything that we have to offer so if that doesn't help you feel free to call any of our four offices that's right now we talked about five that were for sale but as we talked about the beginning of the show I'm gonna step out now let Jennifer tell you more about rentals Ray Brown Williams real estate services currently has many leasing or rental opportunities there are multiple commercial strip plazas in Johnson and Floyd counties offering great locations for your business rbnw also offers residential leasing options in Johnson Floyd and Pike counties including the Pipeville Commons apartments the Commons now offers a media community room and fitness facility for our tenants plus we have an on-site property manager feel free to call any of our four offices for information on our available commercial and residential rental spaces thank you for watching our show this week we will see you again soon


Side here, step a little bit to the left and the loater. Pop and loater are very useful first, but you can do your pop one too, and then third one, okay. Outside to the side, rotate it to the back, to the side, back up slowly.


From theCUBE Studios in Palo Alto in Boston, it's theCUBE, covering and powering the autonomous enterprise, brought to you by Oracle Consulting. Welcome back to theCUBE, everybody. This is a special digital presentation sponsored by Oracle Consulting. We go out to the events, we extract the signal from the noise and we're going to multiple locations to really try to understand better the rebirth of Oracle Consulting. Stephanie Trunzo is here. She's the head of transformation and offerings at Oracle Consulting North America. Stephanie, good to see you. Yeah, good to see you. Okay, so we talked about the mission of Oracle Consulting. Now let's get into it and talk about what some of the customers are seeing. There's this theme in the industry that Gartner brought up about bimodal IT. You guys are talking about trimodal IT. So what is that all about? Well, two wasn't good enough, so we had to add a third. So bimodal IT, two-speed IT, the idea there is a lot of modern enterprises are struggling with this challenge between the systems of record that they have that have to be sources of truth. They're often slow to change. There's a lot of rigor around transforming those systems of record. And then on the second side, on the bimodal side, there are the systems of interaction or systems of engagement, they're sometimes called. And those systems are things like the applications where there's users, customers at the other end, and they need to move at the speed of business. And so the idea of bimodal IT and what a lot of our clients are struggling with currently is how do you serve both of those needs at the same time? There's complications in the processes, the tools, and certainly in the budget. And at the same time, there's kind of looming out there this threat almost that if you aren't in the AI ML data-driven world yet, you're going to fall behind. And so our clients are struggling with the fact that they have not yet successfully addressed bimodal IT, but still have to figure out how to get into this AI space. So our third system, hence, trimodal IT, is the systems of intelligence. The third piece obviously relates to machine intelligence, AI, and ML. It seems like that type of capability would apply to both systems of record and systems of engagement. Is that how you're looking at it? Yes, and so the trimodal IT concept is kind of three different systems and how they interlock and relate to one another. If you think about systems of record, the currency, so to speak, for systems of record or processes. If you think about the currency for systems of interaction, it's the people, it's the users, it's the humans. And the currency for the system of intelligence is data, to your point. So when you're talking about systems of intelligence, collecting and leveraging data from all three systems is going to be what fuels your system of intelligence going forward. And that's the common thread between all three and it just seems to me that is ultimately the underpinning of modernization. I wonder what your customers, how do they view and how do you view modernization? So the awesome thing about being at Oracle is data is our DNA. That's where Oracle started from, that's where we still are today, is data underpins, everything we do, all of the technology that we build is built on the understanding that it must be data-driven. And so when we're looking at all three of those systems and you're looking at it from an Oracle perspective, data is at the heart of even systems of record, of even systems of interaction, not only the systems of intelligence. When our clients are looking at modernization, they're trying to figure out a way to kind of leapfrog this story and get the whole way to a place where they're getting intelligence and insights out of their data. They're not just unlocking it, they're not just moving workloads in a lift and shift kind of model, they're doing it because they want to serve the ultimate outcome that they get smarter as a business. Talk about cloud. Customers want to go from where they are today to some outcome, some endpoint, and they don't want to spend a zillion dollars and they don't want to disrupt their business, they're going to have to make investments clearly. How do they get from point A to point B on that cloud journey? So we've built something called the cloud evolution framework. That cloud evolution framework has several different phases and stages and it's intended to be kind of a skeleton to have that conversation with clients. Are you thinking about all of the things you need to consider to make a healthy decision that has a real roadmap behind it? To your point on budget, and this is part of the Trimodal IT conversation, is they're struggling, I've talked to so many CIOs who are struggling to figure out, right now I'm spending, 90% of my spend is on maintenance of systems versus on innovation. So how do I shift that spending story to something that's actually gonna move the needle on getting the business ahead that's gonna serve my stakeholders who are the lines of business in a way that is not additive to my budget but actually a shift of the budget. And so we're looking at from a cloud perspective helping our clients make that monetary shift, make the shift of the budget where they're self-financing their own innovation by getting smarter and faster on moving their workloads to the cloud. You guys use this concept and others do as well of the autonomous enterprise, you have autonomous database, I wonder if we can drill into that, get past the buzzwords. What is the autonomous enterprise and what's the Oracle's fit there? Yeah, I think one of the big misconceptions when people hear autonomous is that they think it means without people and that's not right. So autonomous means that you're helping elevate all the parts of the system to their highest value which means you don't need to worry about security patches, you don't need to worry about repairing things on the database. Those kinds of autonomous things is the technology helping heal and serve itself. That doesn't mean you don't need people anymore. What it means is two things, you need the experts that can help make sure that you're optimizing the value you get out of the autonomous tooling but it also means that the humans are now freed up to do different kinds of high value work. So an autonomous enterprise would be one where they're really sort of self-actualized in the sense that their technology is feeding itself, it's getting smarter and they're getting insights out of that so that the people in their business are as valuable as they can be leveraging the insights from the technology. So I can see how that trickles into IT, no question about it. Can the autonomous IT organization trickle into the autonomous enterprise? And I mean, I know it's sort of early days but how do you see that shaping up? So these kinds of transformations, I believe are fundamentally across the whole company. And this is true at Oracle as well. We have something called Oracle at Oracle and it's about drinking our own champagne and applying our own technology in-house. So it's not just in an IT organization capacity, it's across HR, procurement, legal, every supporting function that you can imagine. So that cultural change bleeds out across the entire body of the company. And I believe fully that if you're going after something like an AI mission or an autonomous enterprise state, which is an evolution, that you need to involve everyone in the company in different roles. So what's that future state look like? I think the future state looks like a place where you're not just getting incremental gains on business processes or tasks that already exist. You're fundamentally seeing shifts and the way the business runs itself as a result of the technology learning and getting smarter. And the people who are benefiting from that technology changing the way they operate in the company as well. Tri-modal IT, we'll be watching. Stephanie, thanks so much. It's great to see you. Yeah, absolutely, thanks. And thank you for watching. You're watching theCUBE at this special digital presentation. We'll be right back right after this short break.


SNSE is a promising thermoelectric material due to its excellent thermoelectric properties. It also exhibits catalytic activity in the degradation of methylene blue, which is attributed to its non-equilibrium carrier distribution at high temperatures. This study demonstrates that SNSE can serve as a thermal catalyst for organic degradation, especially at high temperatures. This article was authored by Li Fan, XIN Su, Hong Liang Zhu, and others.


Grounded Theory is a qualitative research methodology which involves collecting data and analyzing it to develop a theory about a particular phenomenon. It is based on the idea that theory should emerge from the data collected rather than being imposed upon it. The data collection and analysis process is iterative and cyclical, with each cycle involving the collection of new data, analysis of existing data, and refinement of the theory. The goal of Grounded Theory is to create a theory that explains the phenomenon being studied. This article was authored by Alona Chantai, Melanie Burks, and Karen Francis.


What's up everybody, it's Jason here for JaspysCaseRays.com. We just sold out our last, last one guys. Last filler here to unlock. The last six spots in here for a Sapphire football edition. So I appreciate you guys here. Again, this is for the last six spots. 2021 Mosaic football hobby, one-pack break. We ran and seized the overnighty one. So here we go guys. I wouldn't doubt that Rex.  It comes out in July. We were just talking about that earlier actually that you missed out. So again guys, number 91 Mosaic one-pack break. So first we do the break. Randomize because the name of the team that showed the hits all day at the end. We'll randomize only the names. And top six get in. Roll. Two times. One, two. Two times. Next over down to Steven. Two times. One, two. Cardinals out of the chargers. All right guys, stick to what you got here guys, of course. The rest of the team is dead. Tom Brady. Bucks edition Tom Brady. That's going to Cupperman. Nice little blue there. Out of 99. Well there you go, Jimmy. Jimmy just said he's seen it Rex. What you talking about bro? Justin Fields, Jones. I'm pretty sure if it was shown in theaters people talked about it on social media. It just probably didn't pop up on your feed Rex. People usually always be like posting stuff all that stuff up. Especially on Twitter. Or X I should say. All right, so here we go guys. Hip rate. Last six spots we've been giving away here guys. Good luck. Roll. Four times, one out of three. One, two, three, and four. Four times. One, three, four, four. Top six. Stover, sorry buddy. Hopefully you're still on the top man. Dylan. Dylan. Edward. Stover. So, Jimmy. Congrats guys. You guys six are in. And coming up next is the break itself guys. Thank you.


This study found that pharmacists with formal antimicrobial stewardship program, ASP, responsibilities spend significantly more time on ASP activities compared to those without formal ASP responsibilities. Additionally, pharmacists with formal ASP responsibilities without formal infectious disease, ID, training or certification spend less time on ASP activities and are more likely to perform lower level interventions. This suggests that pharmacist involvement in ASPs may need to be tailored to individual pharmacists' skill sets and experience levels. This article was offered by Brandon Dion, Jamie L. Wagner, Daniel B. Chastain and others.


Hello everyone, welcome to today's lecture. We will briefly look at the various aspects of asymmetric synthesis or asymmetric reactions that we started in the last class. What I introduced was the importance of optically active molecules or the chiral molecules because of the importance in our biological systems, the chiral drugs are important to obtain. In a similar fashion as I also mentioned that some molecules could have a different order or different smell. So that also depends on the enantiomer or the enantiomeric purity of the molecule. Then we saw how the various aspects of asymmetric synthesis are needed to be developed in order to get chiral molecules. In a synthesis as I have discussed that as soon as possible the first possibility at the first possibility a chiral starting material should be available at the beginning of the synthesis so that the possibility of diastereome mixtures are is or reduced. And then we went further to see how the three people got the Nobel Prize, the William Knowles, Ryoji Noyori and Sharpless. These are the people who shared the 2001 Nobel Prize in chemistry for their work in symmetric synthesis. And towards the end we started discussing Sharpless based asymmetric epoxidation. And as I mentioned last time that these epoxides are very important because once we have a very pure epoxide in this particular case an example of this type was taken which was from the pro chiral allylic alcohol. So as I mentioned that in the case of Sharpless based asymmetric epoxidation has to be done from an aryl alcohol. It is not possible to do this epoxidation of an olefin of this kind for example of this kind which does not have an allylic alcohol function. So epoxidation of this cannot be done by the conditions developed by Sharpless. For that we will see later on there are other epoxidations, there are other asymmetric epoxidation. For further time being we will look at how this Sharpless based epoxidation of allylic alcohols to epoxial alcohols occurs. And we also looked at it that we can use a combination of reagents in which titanium isopropoxide is used as a reagent, then tertiary butyl hydro peroxide is used as another reagent, then you have L plus or or D minus tartarate basically. It is an diethyl tartarate, it is a nester. So this is what is the most important aspect of course we have to use molecular sieves which are four angstrom molecular sieves and some solvent like dichloromethane or such solvent. So this is the protocol which is used for the asymmetric epoxidation. All these things are required to be done and this reaction has to be done in a dry medium in the sense that it should be moisture free. Now how this reaction is done? So if we have an allylic alcohol of this type here where there are four substituents on the double bond one of which is C2H. So we are starting with a double bond like this and we are writing the allylic alcohol part like this. So there is something called mnemonic device or a device in which you can predict the possibility of which side of the double bond the epoxide will form. So if the allylic alcohol is kept on the piece of paper for example withdraw in such a fashion that the C2H is on the lower side of the double bond and on the right hand side, not like this. So this is the way we have to orient on a piece of paper the structure of the allylic alcohol that we are considering. So this is how it is shown here. So if we have an allylic alcohol with a double bond like this and OH with the appropriate substituents and if we orient it in such a fashion then if we use L plus DET then the epoxidation occurs from the lower side that is the alpha side. This is the alpha oriented epoxide that means the oxygen comes to the double bond from the alpha side or from the lower side. But if we take D minus diethyl tartarate then the epoxidation takes place from the beta side and the product that is from looks like this. So these are basically the enantiomers of each other. If you look at the structure of L plus DET this is what is the L plus DET and this is D minus DET we can also write the same. This is the Fisher projection and this is of course the 3-dimensional structure like this. So these are obviously the enantiomers of each other and that is the reason why the products that are formed are enantiomeric in the nature. So what Sharpless has actually career out is the epoxidation at minus 20 degrees and whichever diethyl tartarate that is taken it can give either of the two enantiomers as the major product and this is what the mnemonic device allows you to essentially predict the stereochemistry of the epoxy alcohol before you actually carry out the reaction. That is very very important part of the asymmetric epoxidation developed by Sharpless. Now the transition state which defines the stereoselectivity of the reasoning epoxy alcohol is something that we need to really look at it. If we take say for example if we look at the diethyl tartarate which I have shown it here and we can write it in this particular fashion the same molecule and if we see that you have ester group as E written as E then of course we can write it that we have something like this we have OH here and then we have an OH here and this is beta so the other epoxide ester part of the diethyl tartarate would have an ester like this and this is exactly what is what is shown here and when this comes in contact with titanium isopropoxide then you have four of the groups attached to the titanium and then we can expect that two of the isopropoxy moieties are lost when the these two hydroxy groups react with it and of course we can expect something like this to form where we have now titanium and you have an isopropoxide and you have isopropoxide here which would be through the oxygen of course. So this is how it is shown in here so we have the ester group the on the left hand side which is a beta and then this is the ester which is at the alpha side which is pointing below. So this is alpha and this is beta and then of course you have the isopropoxide parts coming in here and the ester group and the could have a chelation with the titanium and what is found is that the species which is a real catalyst is a dimeric in the nature and therefore we can have two the similar molecules are aligned in this particular fashion and they will have kind of chelation something of this kind we have here chelation of this type of techniques and the dimeric species can form which is what is shown here. Now this is the first dimeric species which is actually there is enough evidence to see that such a dimeric species is present during the reaction and actually it is this one which allows the reaction to proceed. How does the reaction take place? Now what happens is that we have this dimeric species to which the tertiary butyl hydroperoxide. Now tertiary butyl hydroperoxide as we can expect that you have here tertiary butyl group which is a large group and of course you have the corresponding hydroperoxide part. When this dimeric species in which this is a isopropoxide and this is also isopropoxide and the tertiary butyl hydroperoxide as you can see here that tertiary butyl hydroperoxide attaches from the equatorial side. Now this is the equatorial side and this is the axial side basically as it is a bidented ligand it is a bidented ligand as you can see it here. So this is the tertiary butyl hydroperoxide part and this is the tertiary butyl group. So the one of the OR groups one of the isopropoxy group is replaced when the tertiary butyl hydroperoxide attaches from the equatorial side and replaces this particular isopropoxide group of and gets attached and of course the oxygen tertiary butyl bond is something that is very important to look at it. So when tertiary butyl hydroperoxide attaches from the equatorial side it needs actually more space because tertiary butyl hydroperoxide is large in size and therefore it does not go to the axial side but it goes to the equatorial side and that is the reason why this attachment of the tertiary butyl hydroperoxide takes place in such a way to avoid the steric hindrance. Once that has attached then there is a possibility of attachment of the second oxygen either from the lower side or from the top side and that is where the tertiary butyl titanium tertiary butyl oxide titanium bond forms from the less hinder lower side that is alpha attack providing energy phase selectivity. That means once the this particular bond is formed the O tertiary butyl oxide bond here attaches from the lower side alpha side that is because this particular ester group is beta oriented. So this particular part does not come from the top but it comes from the alpha side and also of course we have this also being beta. So it comes from the alpha side where only one of the esters here for example in the vicinity is alpha oriented. So this orientation of the titanium O tertiary butyl bond is very important. As you can see that the only other possibility now is left for the allylic alcohol is to attach from the axial side this is what is the axial side and therefore the alcohol allylic alcohol part comes in this particular fashion. And molecular sieves is used basically to remove water and isopropanol from the reaction mixture and thus the reaction is actually catalytic because your the isopropanol sorry isopropanol and water are basically removed continuously by molecular sieves. So once we have decided that the attachment of the tertiary butyl hydro peroxide and the allylic alcohol takes place in such a fashion that the chirality or the absolute configuration or orientation of the L plus DET in this particular case decides from which direction the titanium O tertiary butyl bond is formed and accordingly the allylic alcohol comes from the opposite side. So once the allylic alcohol has attached from the axial side as you can see now the epoxidation onto this double bond takes place from the lower side that means allylic alcohol part is on the top and the epoxide is here and from the bottom side the epoxidation is essentially taking place. If it takes place from the bottom side what do we get is as you can see here that in the transition state the double bond is here which is what is here double bond which is what is shown here and the oxygen is here that attachment is allowing the epoxidation to take place from the lower side. So if we orient in this fashion the parts where this allylic alcohol is epoxide is coming from the lower side and that is how we are writing the epoxide like this. If we rotate it 180 degrees in this fashion then of course we get this particular product as epoxide. So if we look at the strati material what we had was a strati material was like this and we got the product which is like this. So it is very clear that when we take L plus DET then L plus DET allows the epoxidation to take place in such a fashion that if the allylic alcohol is written in this way the mnemonic device allows epoxidation to make the product or lead to the product which has such a orientation. So again once again I want to reemphasize on that in the dimeric species the tertiary group the tertiary butyl hydroperoxide attaches from the equatorial side and then the attachment of the tertiary butyl O bond occurs based on the orientation of the ester group. In this case the ester group is beta and therefore the attachment takes place from the alpha side and this leads to the attachment of the OH of the allylic alcohol from the top and then accordingly the oxygen of the tertiary butyl hydroperoxide is transferred to give the corresponding epoxidation from the alpha side. Exactly opposite of that happens in the case of reactions dealing with D minus DET. For example if we take the D minus DET the D minus DET would look something like this and very clear that when we have a dimeric species this is the dimeric species from D minus DET and as you can see this is pointing actually below it is going below alpha oriented but it is coming towards us below whereas this is going up on the top exactly opposite of what it is here and then what happens in such a situation as I have shown it here that the tertiary butyl hydroperoxide again comes from the equatorial side but then because this particular group is alpha so the attachment of the tertiary butyl O bond takes place from the top side this is the beta side and since it is coming from the beta side the allylic alcohol attaches from the alpha side. So and then the epoxidation takes place in this particular fashion that you have the epoxide forming from the tertiary butyl oxy part and this is basically pointing above the double bond part. So you have O here and the epoxidation is taking place from the beta side. If it is taking place from the beta side and this is how this part is here this part is here then epoxide takes place from the beta side we can get the epoxide alcohol like this because this is the epoxide oxygen. Now if we simply rotate it in this fashion so we will if we rotate it in this fashion as I have shown it here that we get the epox alcohol having this configuration. So again the tertiary butyl O bond attaches to the titanium from beta side and allylic alcohol attaches from the bottom side that is alpha side that is epoxidation occurs from the beta phase. So you can see how different they are with each other exactly opposite we can also look at it in a slightly different way. Alternatively we look at L plus DET this is the transition state the right part of the transition state when we did the L plus DET and we can imagine that its mirror image would be D minus DET. So if we look at it this way we can this is exactly the opposite of each other and if this gives a product like this as we discussed this is the alpha side and this is also alpha side but it is a mirror image. So we can look at this as the product taking place forming taking place whereas in the case of L plus DET this is the product that is forming. If this is the product which is what we looked at it last time last case and then the rotation leads to the product here. On the other hand here now we are looking at the mirror image and of course in the mirror image again the epoxidation is taking place from the lower side also but now this is the product which is formed which is exactly opposite of this they are basically mirror images of each other and now if we just turn out of the plane then we get this particular product. So this product and this product basically are an insurance of each other and they conform to the mnemonic device that we have looked at it in the beginning. So this is another way of looking at the transition state by simply considering the fact that L plus DET is a mirror image of D minus DET and therefore the transition state that we are looking at it can also be the mirror image of each other when we take either L plus DET or D minus DET. So in both the ways we can see that the product that is formed is basically an enunchomer of each other. Now this something that we looked at it last time and that from the mnemonic device and now we can very clearly understand that how does this mnemonic device allow the alpha side attack when L plus DET is used and beta side attack when D minus DET used. So we can imagine the orientation of the allylic alcohol in such a way that when the double bond is written on a piece of paper in a vertical fashion the CH2OH group should be oriented on the right hand lower side and then accordingly we can predict the absolute configuration of the epoxy alcohol during this reaction. Now what is the further development in these reactions? We can start the reaction with allylic alcohol which could be racemic. That means we need not start all the time alcohol which is like this but we can also have a racemic molecule. So if we have a racemic molecule where there is a particular R1 group attached and then what happens is out of the two enunchomers of the starting allylic alcohol one of them reacts faster towards the epoxidizing reagent and gets epoxidized whereas the other one does not react. Obviously if we leave the reaction for a very, very long time then the reaction will give epoxides from both the enunchomers of the starting allylic alcohol that is the reason why this is called as kinetic resolution. That means one of the two enunchomers of the starting allylic alcohol reacts faster. Now how does this reaction happen and why is it so that when the R1 group is beta oriented the epoxidization takes place when R1 is alpha oriented epoxidization is slow. Like if we look at the transition state with L plus DET here. So we can orient the the racemic the asymmetric center of the allylic alcohol in these two fashions. That means for example we have the R1 group as beta here and here we have R1 group as alpha. So if it is beta that means it is coming towards us whereas this particular entire part of the molecule is this part here contained is all is all attached to this one and the hydrogen is going behind and to which this ester group is now having some interaction. Obviously this ester group will have less interaction with a small H compared to the interaction of the ester group with the R1 group. When R1 is alpha oriented that means it is going back side and it is facing the ester group we will have more steric hindrance. So it is H versus E, E is ester which is offering less steric hindrance and therefore faster reaction and that is the reason why this epoxide has formed first and then you have R1 versus ester which is sterically more hindered and it is therefore it is a slow reaction and this is how it leads to the kinetic resolution. Interestingly when this reaction is carried out we can get almost 100% optically pure epoxide and almost 100% pure optically active allylic alcohol which is not epoxidized almost like 95, 98% enantiomeric excess that we can expect. So this is how the kinetic resolution occurs. So we will stop it at this particular stage today and then next class we will see how the utility of these epoxy alcohols can be done in synthetic transformations. Till then bye and thank you.


Hey coach, how's it going? In today's video, I'm going to be talking about how to avoid the pain of starting a new soccer business. Now, when I'm talking about this, you have to keep in mind everything is going to come down to time management. And this is the deal. When I'm working with my clients one-on-one or if they're in my four-week program, I know exactly how many hours they're putting into this every week.  And so this all comes down to number one, managing your time better. And so what I like to do personally is I like to wake up early. I like to wake up very early this way. There's no distractions in the morning. And between the hours of like 6 a.m. and 8 a.m., no one's going to be texting me. No one's going to be calling me. No one's going to be trying to reach out to me during those hours. So that is my time where I know I can work with zero distractions. And this is the thing. Most of the time when coaches are trying to start their business, they don't make that a priority. So it becomes very painful. They think about it all the time, but they're not actually working on it. They're doing a lot of busy work, but that's not efficient. They're trying to work on logos. They're trying to work on their websites. Those are things that are not going to drive immediate sales. My goal is to help you overcome that pain and show you the easy way to build this business. This way you can get clients faster. You're not waiting months. You're not hoping that you're going to get clients. You're going to expect to get clients by using a very specific system. And that's why I'm here right now is to show you that this business is so doable and so achievable. If you're good at managing your time and you follow a system, that's why I created my four-week online business course where you're going to get my personal 101 help. I want to walk you through exactly how to start, how to scale, and how to run this business for as long as you want. This way you're not only going to be the only trainer in your business. I'm going to show you how to hire other coaches in the future. I'm going to show you how to scale at the company. But this is really set up for coaches who understand that you know what? I'm sick and tired of failing with this business or it's for coaches who they're brand new and they know that they want to take their business to that next level and they need help. And that's why I'm here guys. You've heard me talk about this before in other videos or in other podcasts. I'm here to help. And to give you one example, there's a guy named Patrick. He lives in San Francisco. He was one of my clients. He was part of my program and what's including that program is I will get on the phone with you throughout the month to help you out one-on-one. I was on the phone with him for six hours straight and that just shows the amount of care I have for you and your success. I'm willing to do whatever it takes to help coaches who invest into themselves. And that's what that program is about. And if you want to take your business to that next level, I highly recommend you check out that course. Simply go to soccerentrepreneur.com slash coaching. When you go there, you'll see an information page. It'll give you all the information about what's including that program and how I can help you out personally. So that's it for today's video guys. If you want to overcome the pain of starting a business, you need to follow a roadmap. Alright, so that's it. I'll see you later.


So, here we had stopped in the last module we are discussing the analytic method by which we are going to obtain general expression for the wave function for harmonic oscillator this is where we have gone so far we have written Schrodinger equation in terms of this variable psi which is proportional to x and 2e by h cross omega. So, Schrodinger equation has become d 2 psi d psi 2 is equal to psi square minus k multiplied by psi remember it is still Schrodinger equation and then what we have been able to do is we have been able to work out the left hand side d 2 psi d psi 2 we have obtained an expression for it. So, the next step is quite obvious we are going to take this expression and we are going to substitute in Schrodinger equation. Let us do that but before doing that let us rewrite psi as h of psi multiplied by e to the power minus psi square by 2 right. Once we have done that now we are ready to put them together and write Schrodinger equation d 2 d psi 2 of h minus 2 psi multiplied by first derivative of h with respect to psi plus psi square minus 1 multiplied by h multiplied by this Gaussian function in psi is equal to psi square minus k multiplied by h multiplied by the same Gaussian function. The Gaussian functions are shown in blue because it is obvious that they occur on both the sides as factors. So, they are going to cancel each other and this is what we are left with and now we can think of simplifying a little further look at the third term on the left hand side and look at the term on the right hand side both are in h and both contain psi square. So, we can easily combine these two terms and get rid of psi square. When we take the right hand side psi square minus k multiplied by h to the left hand side then we already have h multiplied by psi square minus 1 subtract this from here psi square and psi square cancel sin of k becomes positive and we get this equation d 2 d psi 2 of h minus 2 psi multiplied by d d psi of h plus k minus 1 multiplied by h equal to 0. So, we get a little more complicated differential equation. Now, the thing is in mathematics solutions how to solve this kind of differential equations is known already and one very powerful method by which these equations can be solved is to use a solution that is a power series that is known already. So, we are taking known mathematics and we are applying it in our problem. So, the proposed solution for this kind of equation would be h psi written in terms of well written as a series or you can say a polynomial in psi. a 0 plus a 1 psi plus a 2 psi square plus 1 and so forth in principle this can go all the way up to infinity. So, we can simply write it as a summation sum over j equal to 0 to infinity multiplied by a j multiplied by psi to the power j does that make sense the first term for example is a 0 for that j equal to 0. So, a 0 and psi to the power 0 is 1 for the second term j equal to 1. So, a 1 and psi to the power 1 is psi and so on and so forth. So, that is what we have got we have proposed the solution. Now, how do we go about it simple we are going to differentiate h psi not once but twice with respect to psi and we are going to take those derivatives first derivative and second derivatives plug them back into this equation not only that h psi is itself written as a summation we are going to plug that as well and then we will use another property of power series to get the solution here goes what is d h d psi I am not saying d h of psi all the time right the way it is written it means that h is a function of psi.  So, the derivative of the series power series is also another power series a 1 plus 2 a 2 that is how we get 2 a 2 psi square differentiate what you get you get 2 psi right. So, 2 a 2 similarly well 2 a 2 psi plus 3 a 3 psi square plus 1 and so forth. We can write that as a summation as well and what we will do is since we are going to combine the summations at the end we will keep the limits the same we will sum from j equal to 0 to infinity. So, if we do that sum over j equal to 0 to infinity then what do I get j multiplied by aj multiplied by xi to the power j minus 1. Let us see first term what the first term would be is j multiplied by whatever j equal to 0. So, it does not matter what it is multiplied by it is going to be 0 unless it is multiplied by 1 by 0 then it could be a problem. So, this is the summation sum over j equal to 0 to infinity j multiplied by aj multiplied by xi to the power j minus 1 what is xi the independent variable what is aj is the coefficient of the jth power of i in the power series expansion of h. I will repeat that j is essentially the coefficient for well sorry aj is the coefficient for the term in jth power of xi in the power series expansion of h. So, h is written as a power series we get another summation for d h xi d xi as well and by now it should not be very difficult for us to understand that if we differentiate once again then we end up getting another power series. What is d 2 d xi 2 of h d 2 h of xi d xi 2 what will that be well differentiate this thing with respect to xi first term will give you 0 second term will give you 2 a 2 third term will give you 3 into 2 into a 3 xi and so on and so forth. So, what we will do is we will write it in this form 2 a 2 is essentially 1 into 2 a 2 plus 2 is already there well sorry 3 is already there and 2 comes from the differentiation of xi square. So, we will just write we will not write 6 write down we will write 2 into 3 a 3 xi. So, next one again will be 4 a 4 was already there and the term that was there differentiate once more. So, you get xi square and this is 3 remember we had xi to the power 3 after differentiating once. So, we will write this as summation once again and once again we want to sum from 0 to infinity. So, what should the summation be I will give you a second to write it down yourself without looking and then let us see whether you have got the right answer please write down on notebook what the summation would be for the second derivative of h with respect to xi. Now, I give you the answer this is the answer j equal to 0 to infinity j plus 1 multiplied by j plus 2 multiplied by a j plus 2 multiplied by xi to the power j is that right what would the first term be then j equal to 0 right. So, first term would be 0 plus 1 is 1 0 plus 2 is 2. So, 2 from here a j plus 2 that means a 2 see that is what we have got and xi to the power j xi to the power 0 is 1. So, the first term is 2 a 2 which is in line with this let us go to the third term third term is for third term j equal to 0 1 2 right. So, 2 plus 1 3 multiplied by 2 plus 2 4 multiplied by a j and a j plus 2 right a j plus 2 j equal to 2 here. So, a 4 multiplied by xi to the power j j equal to 2 set please satisfy yourself that this is really the expression for the second derivative. So, now we have expressed our solution as a power series and we have expressed the first and second derivatives of it as series as well what should we do take this first derivative plug it in take the second derivative plug it in and in fact take the original power series and plug it in as well when we do that we get an expression in terms of summation. The first one the second derivative that is summed over xi to the power j the third one h xi itself is sum over xi to the power j what about the second term here the summation is for xi to the power j minus 1 but do not forget that it is being multiplied by minus 2 xi. So, xi multiplied by xi to the power j minus 1 is essentially xi to the power j. So, we end up in this left hand side getting summations in xi to the power j for all the terms write it down sum over j equal to infinity sorry j equal to 0 to infinity j plus 1 into j plus 2 multiplied by a j plus 2 that comes from here the second derivative plus well minus 2 j into a j this comes from here do not forget we have taken epsilon j epsilon to the power j what am I saying xi to the power j common outside the bracket plus we get k minus 1 multiplied by a j right. So, this is the expression that we get and now we will use the property of a power series when we have a summation like this where we use the jth power of the variable and we sum from 0 to infinity it is this imperative that coefficient of each power of xi has to vanish. Sometimes I say epsilon instead of xi I am sorry about that but in case I do please understand what I mean I mean xi. So, the property of power series tells us and this for this you need to read a book on some book on mathematics but right now we will take it axiomatically coefficient of each power of xi must vanish what does that mean that means that I can just write this we do not have to worry about the summation. Let us take each for each value of j each value of j we can write j plus 1 multiplied by j plus 2 multiplied by a j plus 2 minus 2 j plus 1 minus k multiplied by a j equal to 0. So, we have got a relationship between the jth coefficient in this power series for H and the j plus 2th coefficient. So, what we see is that in this series the coefficients alternate coefficients can be expressed in terms of each other.  So, if you know a j you can work out a j plus 2 this is called a recursion formula and what it allows you to do is suppose you know a 0 then you can work out all the even number coefficient. Suppose you know a 1 you can work out all the even number sorry odd number coefficients from there. So, this is how recursion formulae allow us to work out the coefficients and express the coefficients in terms of each other. With this we will go a little further ahead and we will try to find what the wave function actually looks like. So, again we have just brought everything together this is the recursion formula that we had just written and we have said that one can generate even number coefficients from a 0 and odd number coefficients from a 1. So, whatever we need in the subsequent discussion is actually summarized in this slide. Now, we will remember something else what is k? k is 2e divided by h cross and we already know the expression for EV this is where our treatment deviates from the treatment of Griffiths. Griffith has done a more rigorous more general treatment what we will do is since we have worked out EV already we are going to use that expression and try to reach the answer in a little shorter way. So, for v equal to 0, 1, 2 and so on and so forth EV is given by v plus half into h cross omega. So, what we can do is we can just take this and we can put it in the expression for k and it is very simple for you to see that k turns out to be 2v plus 1. Why are we doing this? Just hold on a minute and we will see but first check EV equal to v plus half into h cross omega to get k first of all multiplied by h cross omega you are left with v plus half then multiplied by 2e sorry what am I saying e equal to h cross omega k divided by 2. So, just multiply this by h cross omega k divided by 2 this is what you will get. So, k turns out to be 2v plus 1 I will just give you a minute to absorb that. Yeah, instead of e let us put v plus half multiplied by h cross omega in the expression for k it easily comes out that k is equal to 2v plus 1. So, of course k is quantized that is not a surprised not a surprise at all and also what we see is what we have said earlier k is a positive integer the smallest value of v is 0 so 2 into 0 is 0 plus 1 is 1.  So, what we will do is we are going to plug this into the expression for we are plug this into we are going to plug this into the recursion formula. So, we get aj plus 2 is equal to aj multiplied by very simply 2 into j minus v by j plus 1 multiplied by j plus 2 is that okay 2j plus 1 was already there minus 2v minus 1 so 1 minus 1 is 0 so you get 2j minus 2v in the numerator I have written it as 2 into j minus v. What does that mean or what is the important observation that this leads to it leads to an important observation that well aj plus 2 if you do it very simply is equal to 0 for j equal to v is not it just algebra put j equal to v aj plus 2 becomes 0 what is aj plus 4 aj plus 4 will also be equal to 0 right because whatever you get here will be multiplied by now aj plus 2 what will be aj plus 6 plus 8 10 12 everything will be 0 which means that v equal to j is what defines the upper limit of j j max is equal to v there is an upper limit to j it cannot keep on going okay and it would better be that way otherwise if it really goes to very high values of xi square then once again the function will not be normalizable. So, it is great that we get an expression for j max right now let us consider something so we are saying that it is the maximum value of j so a v plus 3 should also be equal to 0 isn't it which means a v plus 1 is also 0 you are just going down by 2 which means a v minus 1 will also be equal to 0 what does that mean what is the relationship between a v and a v plus 1 or a v minus 1 if v is even then v plus 1 v minus 1 these are odd and vice versa. So, what we are saying is that depending on the vibration quantum number either odd or even numbered amplitudes are 0 let us see we have just suddenly dropped something very profound on you let us see if you understand this what we are saying is this we have proved that j max is determined by v now remember suppose v is equal to even then what are the coefficients we will get the coefficients will get are a 0 a 2 a 4 so on and so forth from there we cannot get a 1 etc but then since we have determined that you cannot have a j beyond v v plus 3 will also not be there and then you can go down from v plus 3 and so on and so forth you can show that v equal to 1 that will also not be there and similarly you can work it out for odd v's as well so either odd numbered amplitudes will be 0 or even numbered amplitudes will be 0 so for odd v values this is what I mean the function h is going to be a 1 multiplied by xi plus a 3 multiplied by xi cube note there is no a 2 multiplied by xi square next term will be a 5 multiplied by xi to the power 5 so on and so forth up to a v multiplied by xi to the power v similarly for even v the function h is going to be a 0 plus there will not be anything in a 1 so the next term will be a 2 multiplied by xi square plus a 4 multiplied by xi to the power 4 and so on and so forth again the last one will be a v multiplied by xi to the power v the only difference between this and this is that here v is even here v is odd so I think it is better to break now and come back for a short third module to complete this discussion so what we see then is for odd v h xi is equal to a 1 xi plus a 3 xi cube plus a 5 xi cube and so on and so forth note there is no a 2 no a 4 so these even numbered terms are all missing when v the vibrational quantum number is odd similarly for even v the odd numbered coefficients are missing they are all 0 so we have worked out the expression for h of xi for even and odd values of v we have learned that both of them go only up to j equal to v now to complete this discussion and build a full description of the wave function we will need to work a little more but let us break this module here we will come back for a short module to complete this discussion


Hey y'all, welcome to What Chelsea Eats. Thank you so much for joining me today. I want to talk to you briefly about my favorite seasonings.  I love all those things, but let me just tell you when I started eating healthy, a lot of the times I would make the food and it would look beautiful and I'd be like, oh, I taste it and it just tastes so bland because I wasn't used to eating these kinds of foods because my taste buds were used to eating junk food and processed foods and you know, fat-laden foods. So I was looking for stimulation in my tongue and when you start and change your diet, you're not getting stimulated the same way you get stimulated when you eat those kinds of foods. So I don't have all of my favorite seasonings here, but this is my top favorite, my absolute top. And my husband has actually said to me when I ordered this online, because I ordered a pound like 16 ounces of it, so I wouldn't run out because I have it and I've just been like, ah, I don't want to run out of that. So I ordered a pound of it. My husband's like, what is that that you ordered from that place? I was like, it's seasoning. It's um, seasoning that I use on our food. He's like, is that what you use on the salads to make the salads taste so good? I'm like, yeah, that's what I use on the salads to make the salads taste so good. So without further ado, here is my favorite seasoning. It's called Benson's Table Tasty and this is the zesty one and I bought the pound. Benson, I don't know if you can see that, but it's Benson's Table Tasty and um, this one is my absolute favorite. Like I do everything with this. When I get finished making my dish, I just sprinkle it on top. So I keep this bottle because this is the one I originally bought and so I just keep filling it up. The other one that I bought is one called Supreme. It's good, but it can't even touch this one. And there's another one that is just like their flagship seasoning. It's good. It's good to use if you're trying to get off salt and you know, things like that, but it's nothing compared to this one. The Supreme to me is good. And so what I'm going to do is put a link down below so that you can buy the set. Like this, there's a set of all the seasonings that are this size. I think there's like six of them. If you buy the six, then you can try the seasonings to see what, which ones are your favorite. That's sort of what I did. I think I bought, I don't know what I did. I don't remember what I did, so I'm not even gonna try to explain it, but I just found that the, this one in the yellow top happened to be my favorite one. My husband loves it. I absolutely love it. It makes my food taste delicious. If you're struggling with healthy food tasting good, be, look at your seasonings because you cannot use the same seasonings that you used to use whenever you were eating a processed foods diet. Like you can't use table salt, like the tables, the white Morton's salt, you can't use that. And even some varieties of salt that say sea salt on them are not good salts. They are processed salts and they've been bleached. And even though they call it sea salt, it's not sea salt. So the only salts that I recommend are Himalayan crystal salt. I can put a link down below the exact one I bought or Celtic sea salt or black salt, salts that have color to them.  If you're going to eat them, go ahead and use that kind. But some people choose not to even eat salt. As a matter of fact, when I use this, this seasoning, I don't even need to use salt because the way they formulated it, they formulated it for people who are trying to kick salt. So you don't even need salt. You can't use that all season all that, you know, we grew up using the thing with the blue top on and orange letters. I think that's what it is. I want to say it's about Morton's, I'm not sure. I'm not trying to bash any company or anything like that. I'm just saying those are not the healthiest things to eat because they are loaded with chemicals and, you know, see, you know, like table salt and things like that, that the thing that kept us in the having the problem in the first place. So yeah, but these are my favorite salts. And I know I sound very passionate about it. You know, I don't work for the company or anything like that, you know, but I'm just saying I know how hard it is to make the transition from eating healthy food, from eating a bad diet to eating healthy foods. And I know that sometimes you need a kickstart and this is one of those ones that those things that has helped me. So anyway, y'all, thanks so much for watching and I'll talk to you all soon. Take care.