I would say the intensity of NTC is off the charts. You're not going to get any training anywhere else in the world like this. They call it the premier training site in the world. What they see here, there's a range of temperatures, there's a range of terrain, and it's something that they're going to have to deal with downrange. You know, all the places we can go, the different climates. You see a lot of it here, depending on what time of year it is. So everything they do here prepares them for downrange. The first thing we tell these JTACs that come here is this is not a cast exercise. It's an integration exercise.  I'd say this is very advantageous. Their days here in the box are going to be a lot harder than some of the days they see downrange. Their enemy here with the op forces. The op forces do this 10 times a year. This is their backyard. So they're fighting an enemy in their backyard. Everything they do has been seen before. So there's going to be mistakes. There's going to be growing pains. They're going to be getting beat down. So when they go downrange, if they are getting beat down, they'll be ready for it and they'll know how to overcome it. For the most part, they're coming here with the units they're aligned with, so they will be deploying with them shortly after. There are some augment T slots, but for the most part, all these people that are here are going to be deploying together down the road. The relationships built here are essential. It gives you that bond between the partners you're working with. So you're not trying to build something when you're already downrange. That way, when you're going out as a JTAC, you know who your ground commander is, you know who your fire's officer is, and you know you can trust them if you're out in the field and you call it for fires or you call it for support, they're going to have your back.


Government says it acknowledges and prioritizes innovation as a catalyst for technology advancement, as it also promises to provide a conducive atmosphere for entrepreneurship to thrive in the country. Minister of Innovation, Science and Technology, Uche Naji, said these are the Made in a Disha, the Southwest Techno Expo organized by the National Board for Technology Incubation which held in Lagos. Details in this report. Small and medium enterprises, SMEs, constitutes to a large extent the firms providing a good number of employment opportunities and intently a vital role in economic growth. Therefore incubating and integrating technology as well as research and development into these SMEs will enable sustainability as well as provide these businesses with other requirements to grow. To mitigate some of these challenges, the National Board for Technology Incubation has brought stakeholders from the Southwest Zone to curate ideas on elevated Nigeria's research and development through tech incubation programs. For the federal government, the place of research and development cannot be overemphasized as it promises to provide the right nexus. The organizers intend to raise awareness and unlock potential capabilities but providing a platform where brilliant minds and creative thinkers, among others, can converge. Ashwa Jibola, Ahmed, Tinobu, Jesse, GCFR, my gratitude equally extends to all our other valued stakeholders within the geopolitical zone and nationwide. The team of these Made in Events elevating Nigeria's research and development output through technology incubation program is out and our life perfected with the President, with the President's former Ahmed Tinobu's Renewed Hope Agenda. Thus we are gathered here today with a common vision. Our modern talents, aspiring entrepreneurs and seasoned experts will showcase their projects, articulate their missions and participate in their role that will profoundly influence the cost of our technology progress. Other keynote speakers say the role of small businesses in social economic development is universally recognized. However, gaining access to resources, finances, research and development are huge but to next. For the Lagos State Government, it will continue to be partners in progress with businesses by creating a sustainable environment for R&D to thrive. Other Southwest governments believe the program will foster innovation and research in startups and beyond. For Lagos to benefit enormously from after, as a new instrument for promotion of trade amongst African countries, technology incubation programs linked to research and development is imperative. This will help attract private sector investment in industry, agriculture and service sectors. The development of nano, micro, small and medium scale enterprises are likely depends on the effective performance of technology incubation. Technology incubation helps entrepreneurs identify their talent, strength, goodness and to develop their ability to recognize when there is an opportunity. There are several challenges which include their small size as a constant, as a constraint for process and product innovation. There are problems in gaining access to resources, problems in research and development initiative, limited leads with knowledge sources and financial questions. Business incubation catalyzes the process of starting and growing ventures by providing tools needed for growth. The stakeholders are hopeful that research and development will bring about this elevation. Hello, hope you enjoyed the news. Please do subscribe to our YouTube channel and don't forget to hit the notification button so you get notified about fresh news updates.


From Hollywood it's time now for Edmund O'Brien as Johnny dollars. This is Carl Bush Johnny. Yeah, Carl. What's new? We've currently got a marine insurance headache down here.  It covers the cargo that's being delayed out there a time clause What reason do you have so far mechanical trouble on the ship one break down after another? Accidental sabotage or both? That's what we want to learn come on down after lunch and talk it over Edmund O'Brien in another adventure of the man with the action-packed expense account America's fabulous freelance insurance investigator yours truly Johnny dollar Expense account submitted by special investigator Johnny dollar to tri-state insurance company Hartford, Connecticut The following is an accounting of expenditures during my investigation of the Yankee pride matter Expense account item one a dollar and a half cab fare to your office Maritime insurance is a bad gamble at best dollar looks like we're on the short end of this one that I know about I bet on Notre Dame last Saturday You aren't alone This is the cargo of tin bound for a west coast plant that's under government contract armament bearings. I think Oh Well, that's where that time clause you mentioned fit, right? I got a deadline so they insured themselves The way it stands that that ship doesn't leave singapore in a week We start losing two percent a day on three hundred thousand You have an office in singapore? Yes, but we haven't gotten any satisfaction from them I don't know that far away. You're out of touch. What's your man's name? Here names elves vincent elves is he addressed? Yeah Well, I guess I can get the rest of the dope from him I'll get out of here as soon as I can get space good nice seeing you johnny. Let me know when your plane leaves I'll send you a bouquet of bourbon or something Expense account item two $1280 airfare and incidental expenses between Hartford and singapore In the perverse way of shipping airlines We arrived with one of melea's heavy muggy dawns coasting in over haze hidden native villages the island started harder finally I finished customs by nine Napt in my room at the hotel europe hotel and I was in tri-state's office by 1 p.m I'm happy to meet you mr. Dollar sit down. I trust you had a pleasant trip out Well, it's a little too long to be pleasant mr. Ells, but those airline people do everything they can Yes, you've uh, you've been in these before a few times now Then you know that the unexpected is more or less commonplace here Then what are you driving at it's possible that you've come on an extremely dangerous mission, sir On the other hand, perhaps it's only coincidence one of my adjusters has been killed He was working on this case. Yes, I'm afraid he was what have you done about it I turned the matter over to the police Did you mention the situation the delayed cargo? I did But I rather think that they categorized him as an individual rather than as an insurance adjuster Who was he a young chinese coup force soon an intelligent chap? I discussed the matter with him the morning previous to his death that was two days ago He told me he was going to visit the ship in question the yankee pride The men on board said he never arrived you don't think his death was a coincidence, do you Instinctively no, but it's true the death isn't where in some quarters here. So I've heard Hey, uh, this boy of yours leave a family anyone I can talk to His parents were killed in the last unpleasantness, but there's a brother they shared quarters I'd like to have the address of course it's in Then coolant street Here you are. I won't bother directing you any workshop fellow will know where it is But I believe he's employed by a dutch concern wouldn't be at home till evening. That'll work out I want to go talk to the chief engineer of that ship first anyway. Yes. I suppose you'll have to go I only beg of you to proceed with great caution the ship is down at the east docks I'm in attack. Come in. Sorry to bother you chief. I What's the matter with you? Blast and fever Seems like this climate brings it back. Alaria. Yeah What do you want aboard my name's dollar? I was sent out here by the company that's ensuring your cargo What about it? They're gonna start losing money if this ship doesn't get started home in a few days. Well There's nothing they can do and nothing I can do I have a bearing flown to me from Hong Kong When that gets here, I can pump water into the boilers and Not before What do you think about all this mechanical trouble you've been having? What do you mean? Well, has it all been legitimate or could it have been sabotage? sabotage Now who'd do that? I don't know. Well, it hasn't been sabotage Bearings go and generators fall up without any help Ask me. I've been nursing them for 15 years When do you expect the stuff from Hong Kong? It's hard to say People don't work the same out here as they do in the States I'll fly up there myself after your bearing if it'll get you out of here on time Look, mister. I'm not in any shape to figure out anything now. I'm sick I'll try and talk to the captain about it Come back tomorrow Oh, yeah Your chief I know that fever's rough After dinner that night I rickshawed towards the address of the dead chinese adjuster I crossed over the singapore river which winds through the city to separate the native and european quarters And entered ben coolant street Was jammed with its people outside to take advantage of the breadth of coolness that comes with night We're here to one good Which store? You've got some other place one. I wait. All right, you wait Are you mister cool? Who asked? I'm an american. I want to talk to you about your brother. I will not talk Why do you come here? I'm working with a company where your brother worked. I came all the way from america Why won't you talk to me? You speak the truth? Yes, I have no reason to lie You come then to heard in america about my brother Oh, but i'm here in singapore to do the same job he was doing when he was killed I wondered if there was some connection Connection? Was he killed because of what he was doing or for some other reason? I do not know. I did not know what he was doing. Are you telling the truth? Yes. What are you afraid of? Why did you tell me you wouldn't talk about your brother?  Did someone tell you that you would if you talked about it? Yes I cannot tell anything because I know nothing That he will not believe who Come on, you can trust me. I promise you I won't mention a word of this He who came here before the police I told him that my brother and I speak of other things not work But he made promise that I'd die if I speak to police Who was this man? Did you know him? No, I have never seen him. Was he oriental or accidental? English He would do low work. I think the work of threatening people for some other And you're sure your brother didn't say anything about his work the night a day before he was killed Anything about a ship named the Yankee pride? Nothing I have spent many hours remembering his last words to me He spoke only of one new thing a woman We've for soon there was always a new woman With this one he was filled with pride and excitement She was Malayan Perhaps she brought him there The man that threatened you did he ask you about her? He asked me everything that had been talked of but I was frightened and did not mention her In our name or where I can find him You will keep the secret I won't even mention that I've met you What will you say? I'll lie about when I got here. I'll tell her I talked to your brother that night before he died Ah Her name is randy There's a place of an Arab in Malabar street. It is called Dili parka That is where he spoke of finding her. All right. Let's see if I can please Of course soon death is a very heavy sorrow But my death is in the future Do not come back To speak further or this would be to waste the future.  I'd come out was enough to tell me what had happened The future that mr. Coo had been so anxious to protect had just ceased to exist In just a moment we'll return to the second act of yours truly johnny dollar starring edmund o' brian But first are you ready to sing it again tonight? You'll find a whole hour full of the day's popular music sung by eugenie baird allen dale bob howard and the riddler You'll hear the tuneful riddle songs that lead to sing it again spant and voice treasure trove $5,000 in cash and 10,000 more in wonder prizes Be listening again to sing it again tonight when it comes your way on most of the same cbs station The phantoms are puzzler, but some cbs listener will win that five grand in cash And now with our star edmund o' brian. We've returned you to the second act of yours truly johnny dollar Telephones are still at a premium in the native quarters of singapore I wanted to report what had happened to vincent elves and tell them where I was going and why So I tried to find one but couldn't The joint called the billy parka Was a mixture of nationalities languages and tobacco smoke I spotted two occidentals as I went in they ignored me. So I ignored them and elbowed a place at the bar What are you doing any scotch? Oh, yes, sir. I've got good scotch. I'll take one. Don't mix it Hey, I'm looking for a girl named randy She hit a man randy You go devil. She's sure you boss you pay her right I'm glad you did sit down Why did you ask for me? Well a friend told me about you. You sound american. Are you that's right? I know some american They'd one teach you to speak english who speak very well No, they do not teach me that I learned from missionary school in penance. You are surprised. I didn't know it shows Everybody is surprised a randy went to school Some american fan told me about me. No, he was chinese. His name was kufo soon He is no friend of mine It's for clerk He told you about me a couple of afternoons ago Said he was coming here to meet you I wanted to meet me all right, but I did not want to meet him. He made fool of himself That would be easy What did he say about me? Oh, that That you were beautiful That he was looking forward to seeing you. He said that because he was lonely I know about men That's why you think of me tonight Because you are lonely As a matter of fact, I am What is your name? Dala, Johnny Dala You tease me. Well, I'll admit it has a ring to it. No I tease you I know the name I'm pronouncing my father workforce teamship line with that name Are you in shipping business? No relation Shall we get rid of the scotch? How do you say? Bottoms up Better now Because he told you about me I got tired of these people I like to talk to you Oh work, will you wait for me? Wait for you only a little while then I stop work. You come to my house. We can talk some more.  He is dead I only knew him that one time Look as well as I know you How should I find out? Why should I lie to you because of the chances are that you're the last person to see him before he was killed How do you know that because he was on his way to meet you and he never came back There are many places to go in Singapore. Yeah, yeah, but it all keeps returning to you or that place Who's whom's brother was shot right after he told me about you? I did not know he had brother Do not want to talk to you like that I gave the name of the place to my rickshaw boy somebody overheard it And the shooting took place right after we left Why would somebody want to keep me away from you? Nobody wants to keep you away from you You are frightened. Ah, that's pass if they wanted to kill me they would have I now Why did you bring me here?  I would help you Hmm Forget it that would be better I will help you forget too I'll make a drink Hi, will I buy sure sure anything Do not think about your death You cannot help them now You think of me What else? Easy now easy sorry to interrupt. Hey, keep your pistol on him Roy. All right. Well. I find out if he's got one He's not on. Ah, well you should know, dearie Well now, aren't you going to get up? I don't see why I should because we're going for a little drive. That's why you should Are you coming like a gentleman or otherwise? Boy, yeah What do you make of me? You go to sleep in a river shack. You're not careful now say on your feet And you wake up on the threshold of a blasted mansion. They give me and Roy. You can't hold his feet yet All right You know you're an important man dollar, but don't get big headed is then that's more important. Thank you Here we are All right, you are go on straight ahead He uh, he was quite um violent sir. Yeah help him to the chair I'd hope this wouldn't happen mr.   I have the power to support them I know all about you why you're here My chief engineer will see that the Yankee pride does not move until I give the word When will that be when I am ready to leave for mexico mech You're crazy that ship isn't going to mexico. Oh, yes, it is mr. Dollar Because I have paid well for passage there. You don't buy ships articles the Yankee pride say she's going to san francisco One can buy anything with sufficient funds The simplest are the petty official signatures needed to make these changes You'd be amazed at how easily eyes are blinded and ears deafened You don't agree with me up to a point I understand You think that I brought you here for the purpose of bargaining with you There's no need for that Why am I here because I enjoy my power And at the moment I'm fighting you and your Stumbling idiotic method.  I'm not impressed.  Two percent of three hundred thousand dollars for each day over schedule Well, please convey to them my thanks Until them I shall cover their loss They won't attempt to prosecute You may go Earl and Roy would drive you wherever you wish them to I retreated to my hotel room But I knew one thing about him and thought I knew something else His name is spotted on an envelope and the way out seemed to be major Ralph Dixon And I had a strong feeling that his weakness was as strength and vice versa The man was power mad Despite of my exhaustion frustration didn't let me sleep too well through the rest of the night This is dala. Well, I don't think for a minute that it didn't happen. What do you know about a major Ralph Dixon? Well, he boasts that he's the man behind our trouble. He's crazy and I really mean that He claims that he's bribed everybody concerned with the Yankee pride sailing including port officials I believe them Look, you have better entree here than I have. Would you see that you can learn? Something about the ship's papers being changed to include a Mexican port. There was no Mexican port. I know that well He says there is and see what you can learn about his visas and passport and you might even check customs He's holding the sailing up for something. I say, uh, what are you going to be doing? Well, I'll start at the other end I know my way around the bottom You aren't afraid of me, but you will be Right now you're afraid of the major and I don't blame you Two men were killed to keep you and the rest of his pawns afraid You and one or two others are going to have to protect him by taking the blame for those two murders You know that don't you that there would be no trouble That was before I came to town. I say there is going to be trouble Because I'm going to turn you in And the major is so powerful that nobody will believe you when you tell the truth You will pay for it all I believe that Well, don't you want to help yourself if you can? Why?  Tell me what's behind it Gold from an Indian sartanet who is afraid of invasion We send their gold out when they can The major is Making the arrangement How much do you know I've only heard Almost 100 million American standard. Yes, America That's been delayed in its journey here What can you do against our life back journey if we can get high enough we'll break him The man I'm working with on this is checking every official the major claims to have paid off How do you know that? What do you mean by that? You are speaking of mr. air. That's right He is only a human being He is as greedy as any of us I do not think he's asking a question He's been bought too, huh? Yes You a captain the engineer officials El you too, Charlie If you were wise Did they tell you to say that? It doesn't matter Yes, I did They told me to warn you I'm glad I hear that Why should you be glad? Because Amizi's afraid of me What else were you supposed to tell me? Only about mr. Elf Yeah Mr. Elves is as good a place to start as any A check on the tri-state office told me that Elves had left for home. So I followed him there It was a cottage set back from the street and answered my knock through the veranda window. I could see why Vincent Elves was sprawled on the floor a pistol just beyond his outstretched hand The way to major Dixon's I stopped at my hotel long enough to get an automatic out of my luggage His own life Perhaps you can profit from his act. I think I can What happened? Did he turn on you? Let us say that he didn't appreciate his position with me. He miscalculated my strength Naturally learned there was nothing left for him to live for How of you fair? I've done all right I've finally realized that there's only one way to stop you What is that?  Obviously here. I'm a man of influence. You'd not be rewarded.  You'll pardon me. I'm sure I know about the gold major Oh You do do you What do you propose doing about it? I'm going to stop it you Don't try to leave major major I didn't kill him as it turned out. I didn't have to police investigation of the shooting brought out all the truth The gold was confiscated when it arrived and after three days of questioning. I was released remarks You may lose two days on the yankee pride schedule But to balance that you also lost mr. L's an agent you can do without Expense account item four three hundred dollars miscellaneous expense account item five same as item two expense account total Two thousand six hundred and eighty six dollars yours truly Johnny dollar Yours truly Johnny dollar stars Edmond O'Brien in the title role and is written by gildowd with music conducted by alexander courage Edmond O'Brien may soon be seen in the paramount pictures production war path Featured in tonight's cast where virginia greg bob sweeney cuter oan bill johnstone walley mayor jack cruisin and ben right Yours truly Johnny dollar is produced and directed by heimey del valle This is bob stephenson inviting you to join us next week at this time when we'll again bring you edmond o'Brien as Yours truly Johnny dollar Their saturday night fun with the younger married set when lucille ball and her favorite husband come along later this evening on most of the same columbia station Now stay tuned for Vaughn Monroe's caravan which follows immediately on most of the same cbs station This is cbs where hop along cassidy rides every saturday night on the columbia broadcasting system


This video will talk about rational applications. Rational functions are needed when we have a concept that involves an idea like per, since they involve fractions. An example would be speed, since it's miles per hour. Here's a few more. Some students agree to share equally to rent a large beach house for one week over spring break. The house costs $1,800 for the week, and if 15 students want to rent the house, how much is the cost per student? Well, they're going to divide it up evenly, because they said equally. So we have to take our $1,800 that we had and divide that by the number of people. And that the way it works, cost divided by the number of people will then give you that each person would have to pay $120. The PIVN represents the cost per student in dollars if in students rent the house. Well that's exactly what we just talked about. We have our $1,800 that the cost is divided by that number of students. So if we want to know, is it an increasing or is it a decreasing function? Well, if you think about it intuitively, as you get more and more people dividing up the amount of money, it should be a decreasing type of function. But let's just look at the graph and see what happens with it. $1,800 divided by X, and that must mean that I need to make my window go to say 2,000. And if I look at my graph then I can see that it is definitely decreasing. So we were right. So it's a decreasing function because the more people you get, the less money it's going to cost you. Finding P of 10, remember our function was 1,800 divided by N, but the N is now my 10. And if I just cancel off the zeros to divide by 10, then I just end up with each person has to pay $180. And exactly what this means in the situation, that's exactly it. Each person pays $180. Find N if P of N is equal to 90. So this time we know 90 and we have to solve for N. Well, remember to solve rational equations we have to multiply by the denominator. We only have one denominator here, so we only have to multiply by N. My N's cancel on this side, and this gives me 90 N equal to 1,800. And divide by the 90, we find out that N is going to be equal to 20. Which means 20 people splitting the cost would each pay $90. So we have this one. Suppose you're throwing a party and you want to share the expenses equally. So again, we're sharing expenses equally. Among all who attend, the band you hire costs $200 and everyone who comes will drink at least $3 worth of food. What does a total cost T for two people to attend? Well, the total cost is $200 for the band, plus the two people that have to show up. Times that $3 that they're going to eat and drink, or $206. Happens if five people show up while you still have that $200 for the band. But this time you have five people that you have to multiply by that $3. So you'll have $215. And if 20 people show up, again you have the flat fee of the cost of the band. Plus you have 20 people that are going to eat $3 worth of food. So now we have $260. How much should each person charge if two people attend? Go back and look. It was $206 for two people, dividing by two, and we have $103 each. That's a lot of money for a party. If we have five, that was $215 that we had to divide up now by five people. And that would go in 43 times, so we have $43 each, getting a little better. And when we had $260 divided by 20, it's $13 each. So what is a total cost function? Well, we've been doing that over and over again, so let's think of what we did. The cost is $200 for the band plus $3 of food times a number of people, right? So plus 3n. How much should be charged? The charge is going to be the $200 plus the 3 times the number of people. But now we're going to divide that evenly amongst those in people, those same in people. So finally, if you want to charge each person $5, so that's the charge, how many people need to attend? So we have 200 plus 3n divided by n. Again, we have to clear our fraction, so 5n is going to be equal to 200 plus 3n. And if I combine my ns by subtracting this 3n over here, then I'm going to have 2n is equal to 200, and n will be equal to 100. And remember, n is number of people, so 100 people would pay $5 each.


So it's a great privilege to be here. It's 15 years from the day I started work as a young lawyer and Since then I've come a long way in public health and access to medicines And I've had the privilege to work with one of the finest Access units in the world, which is called the campaign for access to essential medicines It's a specialized unit of medicine so from there's and we have been working on hepatitis C for the last 11 years From the day I started work in in the access campaign I would like to acknowledge the contribution of our HIV HIV pharmacist to this presentation and the work around access to medicines And I'll just introduce My presentation it has an introduction barriers facing access strategies and responses and Conclusion based on the medicines that we require to treat hepatitis C which are direct acting antivirals So I call them DAAs. So if you just have that question, what is DAA? It's direct acting antiviral So, what's the background from 2005 to 2013? There was considerable debate on treatment for HIV in co-infected patients that means people living with HIV who also had HIV There was also considerable Data to show that if you did screen The cohorts that we had there would be much more Numbers or hepatitis C But we were stunted by the lack of availability of very effective drugs And predominantly by a very old chemotherapy drug, which is called peglated interferon It causes huge side effects It makes people very sick when they're on that treatment Some people told me that it was worse than being on any other treatment that they've ever been they felt more sick than the disease had ever made them and Most importantly it did not have a very high efficacy rate and lastly it was expensive and it was a biological medicine and MSF In its history of treating patients has not dealt very well with biologicals except for vaccines So the whole issue of biologicals faced us We were not able to procure the medicine in time and we decided to wait for the direct acting antivirals So from 2013 and 2015 you see a huge excitement speed up Off-testing in MSF to start screening our cohorts in Myanmar in Pakistan in India And and get ready to treat the most vulnerable populations in the case of Myanmar and Manipur it started with just wanting to treat co-infected patients But as you can see there was a change in prioritization to the most vulnerable community which are drug users in 2015 we started treatment in Pakistan India and in 2016 we are on the cusp of treatment in Myanmar we have the drugs starting to come in which are direct acting antivirals Multiple barriers still exist to treating hepatitis C In the region for example if you look at Ukraine or if you look at Iran or you look at Thailand Malaysia the issue of access to direct acting antivirals is definitely a burning issue So wherever you are going to be operational and wherever you're going to treat for example vulnerable communities whether they are HIV positive or Just simply drug users you are going to need to be prepared to deal with hepatitis C and need for direct acting antivirals MSF strategy was very pure and simple we were focused on getting two good direct acting Antivirals and putting them together into a combination that we could give across genotypes and Make it available to anybody who needed it So it did not matter whether you were a drug user you were HIV positive and so forth So the idea was simplify treatment so much that some of this these discussions about exclusion become moot because the treatment is simple It's like antivirals you combine the medicines you make it simple and you make sure that people have it in a simplified One day a pill or two pills a day and you may ensure that the treatment is short and effective We knew that this was a cure so that means that we did not have to sustain people on a lifelong treatment It was the debate is about eight weeks twelve weeks and so on So it was a short cure and we had if we had two drugs we could treat more people as they came along in our projects We worked very hard with the WHO Technical groups on the WHO new treatment guidelines and Dr. Isabelle was from MSF was part of those drafting committee and We made official submissions to the inclusion of so first be veered into the WHO essential medicine list So we knew that so first be veered and our class we as I call them Sofu and our class we had to get them into the WHO essential medicine list and make them affordable to be able to treat Our patients in the region and across the world Someone many few few people may not even recognize this is a doctor Andrew Hill. He's a pharmacologist He did a study to show that actually the cost of direct acting Antivirals was as cheap as what today and re-retrovirals are so so first be veered the drug that we all talked about in a different projects Is actually just $68 to 136 dollars for three months to make and then duck like a sweet is practically free You can give it free with doctor with so first be veered it's 10 to 30 dollars per treatment So if you combine these two drugs the cost of treatment wouldn't go above a hundred fifty to two hundred dollars He did that looking at the Structure of the molecule and he put that number out and I'm going to talk about why that number was so important to sort of Revolutionize MSF thinking around it because suddenly we realized that this treatment could be as cheap as antiretrovirals Which is hundred dollars per patient per year and we needed to get it down to that price So that we could treat more people and we could see that the impact would be that governments would be excited enough to start viral Hepatitis programs and treat hepatitis C So what did we do The first thing that you do when you want a new medicine is to find out if there's going to be a monopoly on it or not And we went and found the patents and as you said today everyone talks about so first be veered and duck like us We at that time they were just numbers They were seven seven nine seven and so forth and there was a chemical structure and we had to go and find these patent applications All I can tell you is this I had to learn chemistry very fast and figure out which applications related to what and I had a lot of help From a Pakistani colleague of mine mine called Aziz Uru Rehman He's by far the one of the finest patent attorneys. I know who helped me find these molecule structures Pattern oppositions were filed in Brazil China Russia Ukraine Argentina and Egypt on its own initiative rejected the pattern applications filed by a Gilead Sciences to support its own domestic production Egypt has the highest burden of hepatitis C in the world and after that is Pakistan It was challenged in Europe and so forth and of course people followed with a challenge to duck like us we The recommendation from WHO was something that was very much needed came in 2014 Treat all adults and children with chronic hepatitis C infection including people who inject drugs should be assessed for antiviral treatment And when someone just asked, you know, what about will they be stable? Will they adhere? I think this recommendation is based on the fact that you can actually treat drug users the treatment can be simple enough to to Address the needs of people who use drugs. Of course, you do need to give all the other allied support services that are required So the drug sofas baby People in this in this region of the world are obsessed with the price of gold Gram for gram it cost 67 the price of gold in the United States. That's the price of this drug thousand dollars a pill and We had to make sure that this drug was in generic production and available to patients across the region and across the board So was some of the issues that I'm going to talk about is about compassionate use for dying patients price and availability from originator companies like BMS and Gilead patent claims in generic production voluntary licenses and anti-diversion and Delay and lack of registration a regulatory barrier can be as big as a patent barrier sometimes similarly that let us we're more expensive than diamonds My family will always ask me You know, you could be as rich as anybody you should put a few bottles and carry them across the border And it's really funny because that's exactly what everyone is thinking right now Can we come to South Asia and get treated for hepatitis C? Because this has become the hub for hepatitis C treatment again similar issues BMS would not supply duck at us we to MSF for years. We've spent negotiating. We didn't have compassionate use access We had problems with registration BMS does not believe in registering its medicines It just believes in filing patents clearly and of course offering us donations when we couldn't get the drug into the country because it Was unregistered so the donation was completely unsustainable for us So what did we I would say one of the first thing we learned from hepatitis C is that compassionate use is important for patients in developing countries if you have advanced liver disease or you have If you look at HIV or you look at DRTB, you can't wait for the drug to be registered and all the studies to be completed You'll be dead by that time So some clinicians need to go and ask for the drug for those patients who urgently need them and this was something that is now Being used extensively in DRTB where delimited and and and better quillen is not have registered in those countries And we need to treat DRTB patients and now of course for hepatitis C when the drugs were unregistered Treating critical patients is a starting point for all of us and it was really important We started negotiations with Gillard and BMS asking for access to compassionate use and I must say The Manipur project played a huge role in asking and pushing for compassionate use for its patients They agreed to give us name patient access so patient by patient We did very painful paperwork to get the drug into the country and treat patients However, they still charged us so there was no compassionate use There was complete lack of compassion as I would say on the part of the companies They just excluded Asia from compassionate use particularly South and Southeast Asia MSF strategy push us push companies to give us compassionate use access Get companies to file for registration in key countries whether it's Pakistan India Myanmar Whether it's originator or generic companies find a source that will register the medicine So that the drug is available in the country and request waiver of local clinical trial from DRAs Now often we hear a lot of debate around clinical trials But sometimes clinical trials the last phase of it the local trial can take so much time that you may have to Wave it off in certain conditions not always but in certain conditions So a lot of civil society got together for the for asking for waiver on sofas bevere and dakla taswee and the Indian FDA did a Did provide the waiver which is revolutionizing treatment and making available more generics from India for other countries Quality validation of DA is it's a very important issue for a humanitarian organization to be responsible for the quality of medicines that we provide we have besides Encouraging the WHO PQ to speeden up the pre-qualification of direct acting antivirals We ourselves have taken up the whole issue of going to the companies and asking them to apply for WHO pre-qualification and validation They see it as a market entry. We see this as an important marker and quality validation in developing countries There are many license agreement license agreement is about an agreement between two parties in this case a multinational company and a generic company majority of these agreements Include countries like India Pakistan and Myanmar and then exclude countries like Ukraine Thailand So it's a dilemma for MSF to accept these licenses Because some of our medicine some of our patients are on this side of the border and some of our patients on the other side So there's no treatment without borders unfortunately for us due to these license agreements They also as I can if you look at it This is the region that is locked out of access and you will see central Asia completely locked out of ask us And I think this is a big problem with the license agreement Lastly, they said every bottle you must provide a name and you must give the bottle back And that was a very big problem for us. So it was Patient by patient we would get treatment from Gilead. Gilead was worried that the medicine would find its way back into the United States and other countries we refused we do not believe that a company is entitled to patient data and we helped Projects negotiate out of a many of those conditions We still return the empty bottles and we would like to stop doing that in many places But as soon as we have validated generics will be out of this whole issue of wanting to return having to return empty bottles to Gilead So we allied with civil society We spoke up against these unethical practices of pharma companies like Gilead and we also talked about the middle-income countries who excluded from there Outcomes generic sofas bevere has been developed and registered in India Bangladesh Pakistan in Egypt Generic companies marketing the com are marketing the combination of sofas bevere and dakhata sweet There is an internal quality assessment within MSF besides the DRA is registering it two more slides And we have now validated sources from hetero and of course far co pharmaceuticals Egypt Which gives me a great pleasure to see that you know generic production is not only Restricted in to India any longer, but it's taking root in a number of other developing countries more sources are emerging Perhaps Pakistani companies soon will come out with a validated source Treatment with sofas bevere and dakhata sweet will start the medicines are coming into our projects as we speak No more peggillated interferon. We will be free of peggillated interferon in 2016 Thank you So the lessons learned from MSF experience The partnership between medical projects and the access campaign is really important to deliver access And I think it it's also true for NACO and DNP for example I think many treatment providers and people who fight for access need to be together and talk to each other and be able to work Together to deliver access You have to tackle IP problems. You have to tackle regulatory barriers Big farmers donations voluntary licenses are always problematic People need to be more discerning about them need to take a magnifying glass and read all the Closes that exist when they offer you a donation or any other kind of agreement Medical needs need to be met by legal safeguards and pushing for policy change. So in the end Yes, medical projects are important But the whole purpose of of the projects is to push for policy change so that drug users People living with HIV who are co-infected and and people other people who need it are able to get the treatment they need Access to hep C medicines reflects the continued challenges of access to affordable medicines developed countries have reached the pain threshold As I said eighty four thousand dollars For just one drug in the United States. It's very clear. I mean I Would like to say that I have helped the bias Club in India and they take medicines across the world for people in Austria Italy Spain Canada United States and you can see that it's no longer an issue that only affects developing countries It's affecting Eastern Europe for example, and there's a need to build allies and talk to them about access to treatment as well The future Bangladesh they were the first producer of what I call a hope it avir That was a generic of so for severe and this is going to be the future of generic production It's going to go beyond India to South Asia and other countries and of course all the years that people have spent Fighting and marching in and asking for the rights for direct acting anti-virus. So this is was the presentation. Thank you


It started in a more theater background. Was it odd to switch to improvising or ad-libbing? Well, I got rejected from every graduate school I applied to. So it was a pretty easy choice. How many did you apply to? Three. Only the good. I really thought highly of myself. I applied as a playwright to Yale, Juilliard, and NYU, and just got a universal no thanks. Had you been James Franco? I know. I would have like three PhDs by now. But no, I got rejected. And I recently went back and read the play that I had submitted. And I thought I was going to have that thing where you look back at something you wrote and you think, oh, this was terrible. I understand. And I still thought it was pretty good. I think that's better because I think it tells you how arbitrary, particularly in the arts, these things are. It was funny. It was a play about Kant and Newton as 13-year-old boys trying to date girls and debating the nature of space. And it's really funny. I don't know. I think they made a mistake. Well, now you can produce it for money. So screw them, you know?  If everyone walks away with one thing tonight, I think that's the most important.


Warning, this video may not be suitable for all audiences. Your discussion is advised. Okay guys, we're still in Crystal River, Florida. I did a lot of filming on my phone and none of the, even though I formatted the new card I put in, none of the videos have came out so there's a lot of lost footage and I'm sorry about that but we'll be back and show you where we was. Monkey had the same problem. Mine was working fine until today and they're both doing the same thing. We bought these cards offline so there's a problem there. But anyway, as you can see, we're out in a beautiful place, right? But look at this. This is kind of sad. It's kind of messed up. Got this tarp here.  I mean, we found out that some of it is dumping and some of it is homeless. Now if you're homeless, I understand. Okay, but when you're asked to leave, you pack some of this stuff in and they say I'm homeless. How can I pack it out the same way you packed it in? At least put it in a pile for someone to clean up. Look at this.  You know, look at this.  Well, they got money because they can't handle. Now the people that can't handle that need the money. I understand. See, some of this is dumping. Okay, some of it could be washed up for the hurricane, whatever. This is not. You know, how'd you get it here? Take it back with you. You know, that's why I feel about it and it really pisses me off that there's a lot of people that do this and, you know, they got a thousand dollars in their pocket.  You know, we don't have a thousand dollars in our pocket and we work every day, both of us, all day.  You know, it's terrible, isn't it babe? Yeah. Makes me sick. Yeah, it's beautiful out this way. I know. But then, anyway, back to the, but then, you know, look at this. I mean, they got stuff tied off the trees. It's terrible, right? Yeah. I don't know what you just mumbled but. It is terrible.  Some beautiful place like this for us to come and enjoy and then you got people out there making more money than we do but they don't think they have to pay for anything but, okay, fine.  It really pisses me off.   Look at it. I think this may be a dump site. I don't know if this is a dump but even if it is or homeless, whatever. Why you want to do this? You know, you got brawls here. You know, you've got shorts here.   Just underneath this. Look at this canopy. Look how beautiful. You know, you're looking at this going, oh wow, it's so shady.  Now, I want to know why this is government property, why the county, township, whatever the case may be, they can't afford to have somebody come out here and clean it up.  I'll clean all this up, make it look like spotless in the very next weekend. Give me Friday, Saturday and Sunday and take camp here for free.    Really? Really? Pisses me off. Sorry, babe. Well, don't it?   Well, they made us leave. Well, guess what?  How? We're homeless.  All right, let's go to the next place and leave it like this. I granted some of this is, you know, just dump site, which another thing, you're dumping. If I catch it, guess what?   What? Really? You're swearing. Oh, I'm swearing on YouTube. That never happens. Oh, well, I think it's a cool spot though. It is, it's nice, but leave it, but yeah, but leave it for the next person, you know, to enjoy. Yeah, they made quite a mess on here. And we're so far away from the nearest gas station, if it's paying handlers, they're not going to walk that far.  Well, it's ripped. Leave it. Even though we packed it in, let someone else pack it out. I'm sorry, babe, but you know what?  This is my country. This is my land as well as yours. You know, I pay taxes. You pay taxes. I mean, look, there's wiper stuff here. Why bring it out here and dump it?  Yeah, they were living out here. You know, God. But yeah, some of this, like that, I'm going to say was probably from the homeless because you know, they don't want to step in the mud. But like this children, hopefully this children stuff, Fisher price and all this kid stuff, hopefully not just dumped or just dumped and not that they were living with children out here. Look at this. Look at this. I've seen that. But look at this right here. We got a Nike shoe. Jesus Christ. I never owned a Nike shoe in my life unless it was given to me and it was probably half worn out then. But look at this, you know, so and then leave the stuff. I'm sorry, guys, but this my rant. And you know what? No holds barred today because this pisses me off.  This ain't this ain't from the hurricane. This wasn't here from the hurricane. You know, I was a year ago, almost a year ago.   Like she said, look at this coolers, big old suitcase.  What's all that green yellow stuff? You know, there's, there's a flashlight. You know, there's a little cross there.  That's, that's what you care, you know, about the good Lord. I'm sorry, but man. Anyway, guys, sorry about that rant. Sorry for my language, but I'm not gonna bleep any of this out. I'm not, I'm not gonna edit it. It just people need to see the plate of a beautiful place. And like I said earlier, damn, why, why, you know, and this was bought apparently at a yard sale or a thrift store. It says $1 on it. You know, come on guys. If you're watching this and you do this shit, contact me. I'll talk to you. I'll meet you. I ain't scared.    And apparently, this shit's been here for a long time. Apparently, the government's not gonna clean it up either. So I'm sorry guys, but you know, my rant. Sorry. But anyway, we're having a beautiful day. There you go. Look how beautiful it is. Our memory cards aren't working right on our phones. Like I said, so but we'll we'll make up for it. We'll come back. Hi, babe. Say bye. All right. All right, we're gonna we see something more interesting. We will get back with you. Thanks guys. Bye.


Mystery House, that strange publishing firm owned by Dan and Barbara Glenn, where each new novel is acted out by the Mystery House staff before it is accepted for publication. Mystery House. Well, Barbie, a murder story about airplanes tonight, is it tough to solve? It looks like you know the identity of the murder almost right from the start, but you wonder if the police will ever find out. Oh, a frame-up, huh? Well, I like that kind of a story once in a while. Oh, this is the honey of a frame-up, one that doesn't seem to have any loose ends. But right triumphs in the end, hm? Well, Mr. Glenn, I'm surprised at you.  We're talking about rights at the end of the story. Everything's right in these stories, right from the start. Just listen. Okay, Tom, places, everybody. Set the scene for tonight's story, will you? Operation Murder. The scene is the office in an isolated building where Anne Logan, former woman's speed pilot, turned aviation engineer, is working on a government-sponsored secret experiment. Doug Ward has just come in. Doug, what's the idea of dropping in on me here? You'll know I... Yeah, sure, I know Anne, but I was just driving by when I saw a very shady customer coming out of your place. What do you mean? A guy named Lopez. As soon as he saw me, he ducked. Lopez? I never heard of him. Maybe some friend of Austin's. Well, this guy's nobody's friend, Anne. I had plenty of trouble with him way back when I was flying in Spain. Well, I'm not going to worry about him. That's Austin's department. Well, you're kind of leaving everything to Austin these days, aren't you? Austin is important to me. Sure, I know. You got yourself engaged to him because of his bankroll. Anne, how could you sell out like that? I didn't sell out. Austin Ames is... Well, he's done more than anybody to make this operation successful. Okay, so he put up the dough... Hits more than that, Doug. He's seriously interested in the future of aviation. He's not just a... That's right. He's no stick pusher. You know I never called you a stick pusher, Doug. It's just... Well, I always hoped you'd grow up and get serious about flying. Doug, you could amount to something. It's a laugh. Do you know anybody who's done more flying than me? Sure, you're just about as hot as any flyer in the country on stunt stuff, but you're not young. You ought to settle down. Why don't you take the job I offered you? No, thanks, Angel. I don't need charity. There's still dough and test stuff. But any day now your nerves will get you and you'll be grounded for good. What'll you do then? I'll get by, Anne. Oh, sure, any bum can get by. But you know too much about flying to let it go to waste. Look what an amateur like Austin can do. Why, you... The main difference between your pal Austin and me is that that bank account of his. Now, maybe if I'd have had that, you'd be engaged to me instead of him. Oh, please, Doug, don't start that again. You know, we had that out long before Austin and I were engaged. Okay, Angel, okay. I just don't want you to forget that I'll always be available. Oh, Doug, Doug, if you'd only grow up, get a serious interest. You could change if you wanted to. Look, Anne, don't try to keep making me over. I could sweet talk you, baby, but you know cloud hoppers like me don't change. I'll be a stick pusher until they ground me. But you don't want me that way. That's right. I want a man with a purpose in life. Oh, hello, Austin. Hi, Anne. We're all set. Hello, Austin. You don't mind if I visit your future bride, do you? Oh, I didn't see you, Warren. I don't like to seem rude, but you don't belong here, you know. Now, Austin, don't be that way. Doug's an old friend. That's all right, Anne. I'll take off. No, Doug. Austin didn't mean it that way, did you, Austin? Anne, this office is full of secret plans. We swore to protect until this plane is ready. Austin, aren't you forgetting? Oh, that's all right, Anne. Wait a minute. Maybe I am a little touchy. Working under pressure, I... Well, you don't have to worry about me, old timer. I haven't seen sign of your secret plans. Oh, you two. Why don't you be friends? I was just going to suggest that... Doug, we could... Well, we could make a good spot for you. Now, that's more like it. I was just telling Doug... Oh, no. I'm not on the skid yet. You don't get it, Doug. This is a big operation made to order for you. Sorry. How would you like to make the first test of our new plane? Wait a minute. I'm going to make that flight. After all... Now, take it easy, Anne. I know you counted on this. Count it on it. I'm going. Anne, we need publicity. The kind we can get with Doug as a pilot. He's the best known flyer in the country. That'll get us twice as much space in the papers. Look, that plane is my baby. I've given her everything I... I know, I know, darling, but your safety means too much to me. I couldn't think of you cracking up. What are you so excited about? Anne's as good as they come. Well, if Doug would, I might be willing. I knew you'd see it, Anne. You've always wanted Doug as a partner. No, I'm not so fast. I might do this test, but... If you would, Doug. Well... Well, it's only because I don't like to see you taking chances, Angel. That's the spirit. We'll work out details later. Oh, it's going to be good to have you around, Doug. Sure it is. We can take a look at the ship now while you're cleaning up, Anne. Well, why don't the three of us go out today? Sort of celebrate. And what is this? I just said that... Sure, sure, Doug. But Anne's just happy to have you with us.  Okay, Angel. You wear that favorite dress of mine and I'll go. That's a date. Take care of him, Austin. I'll hurry. Metta girl. See you soon. Well, Austin, you sure you go for this deal? Of course. Well, I just thought that... Forget it. I trust Anne. And besides, we couldn't let her take any chances on this test flight, could we? Well, there's always that million to one... Sure. And besides, there are certain details I don't think Anne could handle. What do you mean? Anne ought to know all about her own plane after all she designed it. Of course. That's exactly why. I don't get it. It's because she did design the ship that I can't let her make the test. What's that? Anne would make a success of the test or die in the attempt. Oh, you mean if somebody's got to die, you'd rather it be me. Not that. I just can't afford to let this be a success. What? Oh, I've got reasons. You see, I don't have as much money as Anne thinks I have. So when I get this offer... What offer? Never mind that. I need money to keep Anne in business. Well, but if this test flight's good, you'll have all the money you'll ever need. If it's successful. But what if it isn't? Well, any designer takes that gamble. Failure means you may go broke. Well, I'm not taking that chance. We're going to fail and get well-paid for it. Very well-paid. Oh, come on. Talk sense. Anne doesn't go for failure. That's where you come in.  Now, wait a minute.  Oh, so that's the angle, huh?  Oh, no, I'm taking off. Not so fast, Birdman. I'm afraid you'll find it a little difficult to get out of here. Yeah?  That's why I made other arrangements.  Come on in, Sammy. Our hero is going to require some persuasion. He doesn't seem to realize he's involved in a very melodramatic situation. Okay, boss. Just let me... Is this over-stuffed character part of the melodrama? This dog is Samson. He used to be a circus strongman, but he found my kind of work pays better. Okay, boss. Now... Get away from me, muscle bound. Just keep an eye on him, Sammy. I want my friend, Doug, to understand the plot. Hey, Austin, you haven't seen enough movies. Don't you know the hero always comes out on top? Does he? Yeah, he does. For instance, I haven't forgotten... Hey, you! Oh, my arms! No, it's not busted.  I've got you covered. What? Oh, guns make you nervous, don't they?  I don't want to shoot you. Yeah. Sammy. Here's one for you. Catch! Nice throw, boss. Now, Birdman, you've got you covered from both sides. Ah, fast work, Austin. Maybe the movies could use you. Just shut up and start moving. And remember, there are two guns in your bag. You think this is melodrama, Birdman? Take a look at that plane. Wow. Hey, I got a hand at the end. She sure did a job of design on this, baby. So you're impressed, huh? Well, just watch, Sammy. He's going to do a few tricks with that window over there. Hey! What's the idea? That's a sure way to get the cops here. Absolutely. That's part of the plot. Okay, genius. You got it.  Oh, me? You. Remember? In this plot, the hero is the fall guy. Now, just climb up there in the cabin. We need a few fingerprints. Oh, so that's why you always wear gloves. Get up there. There is much time. All right. Okay. Come on down now. Look, what? What? What kind of a brainstorm are you having? Come here now. Look, take a look at this engine. Well, yeah. That's right. Get your hands in there. Now, Sammy. Yeah, boss. You keep him covered while I get these Emory filings ready. Emory filings? Well, you cut the heart out of that motor.  Well, that's one of the oldest tricks there is. Anybody knows that Emory filings... Sure they do.   Let's get it over here. Oh, Sammy, do you hear me?  Help, I... I've been... I've been... Hey. Hey, Austin. Austin. What's the matter with you? Great Scott, man. He's dead. Dead? You...   No, I didn't. I didn't. I didn't. I didn't. I didn't. No. No, I didn't.  It was an accident. It must have been. What? What's that? Come on. You... It wasn't you. Somebody over there. It was an accident, doc. Han. Han, where are you? What? Well, it was an accident, wasn't it? You saw... Was it? Move back a little, doc. I want to see if Sammy's really dead. Funny, isn't it? Well, it took care of poor old Austin. But it took two to finish Sammy. Tough, wasn't it? Man, you're crazy.   Don't try anything smart. I'm going to call the police. But you just killed Austin and Sammy. And you're going to call the police? That's right, darling. I'm going to call the police. So you better scram. They might find you, Doug. Oh, and for the love of Mike, find me while... You see, Doug, I know this place like a book. I can get out of here without anybody seeing me. I don't think you can. Oh, they'll find you all right. And wait a minute. Where are you going? You shot these men in cold blood. You can't... Can I, Doug? So long, and happy landing. They push her. Will she get away with the cold-blooded killing of Austin Ames and his bodyguard, Samson? Will Doug Ward be able to convince the police that he did not kill Anne's partner? Well, the second act will answer those questions. But in the meantime... Act two of Operation Murder. Police detective Juergens has arrived on the murder scene and has begun to question the flyer, Doug Ward. Oh, you take me forward. You'd better start talking if you want to have any chance at all. I told you I didn't do it. Sure, sure you didn't do it. But you were sitting here when I come in, weren't you? You admit you were fighting with these guys. Well, I didn't kill them. I told you that. All I know is the shots came out of the dark behind... Behind those empty crates. Well, who was it then? Who was behind them boxes? I can't tell you. You can tell me and you will tell me or you'll hang. Who are you protecting? Come on, Ward.  I didn't murder anybody. Well, maybe you'll start talking when we find the fingerprints on the gun you left lying here. Look, I didn't have a gun. I don't even carry one. Okay, so you took it off of one of these guys. Everybody knows you were sweet on that gal Anne Logan. You were jealous, weren't you? Oh, but not like you were trying to make it look. You were mad because Ames was in on this new plane that that Logan girl designed. You figured you could make it look like Ames was no good. Oh, no, you're crazy. We came here to jimmy up that plane and you figured to make it look like Austin Ames had done it. I tell you, you're wrong. And it all figured out, didn't you? Only Austin comes along and catches you at it.  You killed Austin Ames and then you shot Sammy because he was a witness. No, you've got it all mixed up. Anne... What about Anne? She telephoned the station and she'll be here in a minute. All right. Anne Logan was a friend. I was going to make the test flight for her. She asked you to? No. No, Austin did. It was double crossing, Anne. He wanted to make the test flop and he tried to hire me to pull a funny cracker. Well, then why did you kill him? Wouldn't he pay you enough?  Oh, no. No, Inspector, you don't think Doug Ward killed... Oh, he couldn't have. Anne... Surely it couldn't be Doug, Inspector. Doug had agreed to pilot the ship in tomorrow's test flight because Austin didn't want me to take the chance. He did, huh? Yes. Of course, Doug and Austin weren't very good friends, but I guess Doug felt it would be better if I didn't take the chance. You know, you can't always tell about new planes. Is that why your friend Doug came here tonight? Because you and Austin invited him? No. I guess Doug was curious about the plane. He just dropped in and asked if he could take a look. And you took him out to see it? Why, no. Doug is a friend. I knew, of course, it would be all right for him to go alone. Alone? Yeah, sure, he was alone. That's right. Austin and Sammy went out a few minutes later, and then I heard shots. I didn't know what to make of it. I was frightened, and I ran out to find help. Oh, so that's the way you want it, huh? Well, I'm sorry! Hey, hey, hey, stop him! He's getting away! What do you mean, break? This makes the second time today you've tried to ignore me, Lopez. I do not know you. Get out. Oh, you know me all right, Lopez. That's why you're so nervous. You've been worried about me.  No, no. Not until we've had a little talk. And don't reach for that desk drawer. Have you forgotten, Lopez, that I'm an expert on judo? Quiet! What's the matter? Make you squirm? All right. You are Doug Ward, and I am Raymond Lopez, but this is not spin. I told you not to reach for that gun. Listen, Ward... You ought to learn to act better, Lopez. Now that you're an airline executive. This is a legitimate business. Sure. What do you want? How much did you pay for the plans to Anne Logan's plane? What? You think... You heard me? How much? Let me go. Let go of my arms. Look, I saw you coming out of Anne Logan's office. I know your tricks. Now, how much? No, no, I can't tell. Look, Lopez, you've been selling your services to one country after another. Your reputation isn't worth a nickel. I am. Now just tell me how much. How much did you pay for the plans? All right. $300,000. $300,000? Anne. You see, Miss Logan? Here he is. Doug, Doug, I was searching for you. I was so sure we wouldn't find you here. What? May I ask what is the meaning of this? It just means that... No, no, Inspector. I'm sure you're wrong. There must be some explanation for Doug's being here. Well, Anne, you know darn well why I'm here. Doug, you misunderstand me. I just told the Inspector what you said about seeing Mr. Lopez. What? Well, I only thought... You see, if Doug was right in saying he'd seen you near my office, that must mean you'd come to see Austin. What's the game, Anne? I'm so sorry about this, Doug. If I'd had any idea we'd find you here, but I only thought Lopez must know something because of all the things you've told me about him. What is this? Well, Doug always said if I ever wanted to sell out to a foreign country, that you were the man to see. Looks like your goose is cooked, Ward. What? Do you mean you're falling for her story? No, none of that, Ward. You won't need me anymore, will you, Inspector? I'm so unedged. Do you mind if I go on home? Sure enough, Miss Logan. And thanks for having that hunch about Lopez. Doug, I'm really awfully sorry. Look, Jerkins, are you going to let her... Fight down, Ward, and start talking now. But she... Sure, sure, she was too smart for you, wasn't she? You shouldn't have blabbed about your friend Lopez. Listen, why do you think I came to this guy's office? Get him to tell you about the 300,000 bucks he paid out for the plans to Anne's plane. It is a lie, Inspector. I demand that you take this man away. Look, Jerkins, this guy's bad medicine wherever he goes. He's admitted that he paid out 300,000 berries to get the design for Anne's ship on condition that the test flight was called off. Now, he paid that money to Anne Logan herself. What? He is guessing, Inspector. He knows nothing. Oh, yeah? Well, then what were you doing in Anne's office? It is true. I went there but not to see Miss Logan. I make my arrangements with our partner, this Austin Ames. What arrangements? The people I represent pay Austin Ames to make sure the test flight is a failure. But it is understood this Doug Ward needs to be the pilot. You mean that Ward was to fix the plane so it would crash? That is correct. Our Austin Ames anticipated some trouble in persuasion.  Is that it, Ward?  The killer is your friend, Anne Logan. Anne Logan? That's right. I saw her do it. What? You told me you didn't know it. I know, I know. I couldn't figure out why she did it then. But when she began acting sorry for me, acting like she was defending me, I realized I was supposed to be the fall guy. What was her motive then, if your story is true? Money. Austin Ames was her husband to be. She wanted his money, not him. When she got engaged to him, she got him to make a will in her favor. Are you guessing or do you know? I'll bet on what I say being right. Look, if you just let me talk to her, I'll ask her some questions. I can trap her. I know I can. Okay, then come on. Then I am free now? You're gonna have to answer some questions about those plane plans and that money, Lopez, but we'll take care of that later. Just don't get any ideas about getting away. Come on, Ward. Miss Logan, you startled me. What brings you back to my office? The policemen and that flyer ward, they just left for your apartment. I never went to my apartment, Lopez. I waited outside, waited till they left. I saw them leave. That was clever, Miss Logan. But why? Because I wanted to talk to you alone. Without anyone hearing us. What about? I knew at this plane design business, Lopez. A lot depends on what happens to my first job. Ever let a story get out that I was mixed up in a sellout to a foreign country and I'd be licked? Done. Nobody'd give me another chance. I've got to know, Lopez. Were you dealing with Austin or weren't you? I am afraid I cannot discuss my business affairs with you, Miss Logan. Oh, yes, you can. You can do that or answer for two murders right now. Me? Two murders? First you tried to blame the flyer for them and now you think you can change to me. I doubt that, Miss Logan. I doubt it very much. I saw you kill them, Lopez. So you dropped the gun and run. I picked it up and went ahead. You think you would make the police believe a story like that? Fantastic. Particularly after what you have said about Doug Ward. Oh, no, it's true, and I can prove it. I had my gloves on, Lopez, and I guarded your fingerprints carefully. They're still on the gun. I imagine the police could trace it to you if I told them where to look. You made a mistake coming here alone, Miss Logan. What? You had that gun? So you admit it?   Not here. I can do it and admit it freely.  But I shot himself to fence and I can take care of the fingerprints on that gun. So there are fingerprints.  It doesn't make much difference now, Miss Logan, to you or to me. But why? Why would you do such a thing? Ames made a deal with me. He took the money. And he insisted he'd get Doug Ward to crack up the plane so the test would be a failure. But Doug Ward turned down the deal. I knew he would talk. I couldn't afford to have my operations known. But why didn't you kill Doug? And let Austin Ames have that over my head? No, my dear. That wouldn't have done at all. And now? No. No, you can't shoot me. I'll shoot to kill. Where's Hannah? Are you hurt? He just got me in the shoulder. But how come he came back? You came here with me, remember, Miss Logan? You said you were going to your apartment when you left here. She lied. She stayed here. We heard why she stayed here, Lopez. But how did you know I'd be here? Well, you came with me and there wasn't a cab any place around, not for blocks. Didn't seem like you could have gotten far enough away so we couldn't see you. So we came back to see what you were up to. We heard Lopez's admission of the murders. You could have told me about him before. I had to be sure about Austin Ames being a crook. I had to know about Lopez playing there with Ames. I'm sorry I had to mix you into a duck, but I wouldn't let them convict you. And there had to be somebody to keep the police interested until I could talk to Lopez. Well, you were handy. Handy? But I won't be from now on, Ann.  No, I'm gonna stick to test flights from now on for a guy isn't risking his life all the time.


Are you one of these students who doesn't take things for granted but ask questions such as how useful Crombach's Alpha truly is? Classesma, psychometrician in our department, has done research on that and most scholars would be surprised with his findings. Classesma is also the former head of our department and currently the dean of our school. He is also the founding father of the research master programme that you are looking at. Professor Jürgen Vermund is internationally known as the expert in latent class analysis. He is really keen on getting you convinced about the quality of the method and he undoubtedly will do that. By the way, my name is Guy Mors, I'm the minor coordinator of the methodology and statistics track and my field of expertise is survey research. Students in the research master all have keen interest in doing research but a small group who is interested in doing research on methods and statistics has been focusing on a number of issues. You might wonder which topics that they deal with. I'll present you two of them. First of all, we all know that developing scale involves making compromises between on the one hand practical considerations that a scale should not be too lengthy but on the other hand methodological requirements saying that a scale should be lengthy enough to be able to have reliable data. Well, the question how short a test when a short test becomes too short is a topic researched by one of our research students and who is finishing his PhD on that. The second example. Multilevel data involve data at different levels in which individuals for instance are nested in schools or citizens within countries and multilevel methods have been developed to analyze how these group variables explain differences between individuals. But what if it's the other way around? That you like to explain group differences with the visual level data. It's not that obvious. Well, one of the research master students has developed his research on that. We have the one minus beta. That's the real logo of our department. But you have the power as well. You have the power by joining our team and then you'll experience the luxury of individual traineeships, traineeships which often involves cooperating with staff members in trying to publish papers and getting them published in high quality journals. It's moving into PhD tracks. First year papers, master thesis have been published in our department. So if you're join our team, you're in the real business of doing research, not just practicing. And that is what really makes the difference. And finally, some things that our foreign students told me to tell to you is that, well, how nice is that everybody talks English in the Netherlands? It's one thing that they learned a lot of things that they never heard of before when they entered the program, but best of all that they were given the opportunity to enter a PhD track and they are getting paid for that. So if you have interest in medicine statistics, you have good grades in related courses and you're into the challenge of our research master program, you're welcome. Just give us a mail. Thanks.