Good evening, everyone. I'm Dr. Sarita Sarkar from SCV Medical College and Hospital Cartuck. I'm going to present a case series based on role of ADC in predicting the grade of the brain tumors. So, coming to the introductory part, as we all know, brain tumor can be diagnosed with a conventional MRI sequence that is T1 and T2 weighted images and post-contrast MR, post-contrast T1 weighted images. But those sequences are considered to be inhibition in diagnosing the aggressiveness of the brain tumors. For this purpose, recent studies have shown that there are the need of other imaging modalities like DWI and ADC. DWI or Diffusion Weighted Imaging based on measuring the random Brownian motion of water molecules in the biological tissue and is particularly useful in the tumor characterization. The extent of the tissue celerity and presence of intact cell membrane helps to determine the impedance of water molecule diffusion. Higher the cell content in the tumor or the high grade tumor shows high diffusion restriction and the low ADC value. This is the base of our study. So, aim of aim and objective of our study was to apply the ADC values to quantify the difference between low and high grade tumors and project it with histopathology. So, the data were collected from the patients attending to the department of radio diagnosis being primarily referred from the department of neurosurgery. The study period was 11 months and done on 60 patients. The study design is retrospective study. All patients of brain tumor where performed MR scan using G-sigma HDX machine with 1.5 tesla field strength. We performed the standard MR protocol and then calculated the ADC values of ADC values in the areas of greatest restriction diffusion in the solid tumor components. Then the histopathology reports were correlated individually. The inclusion criteria is the patients having DWI and ADC sequence in MR study. Only collision measuring more than 1 centimeter in diameter were included in the study. The histopathology consistent with high grade tumors and few benign tumors and we included all age group. Exclusion criteria, there were no ADC and DWI sequence in MR study and because histopathological report, patients measuring less than 1 centimeter on MR or artifact in DWI. The study was conducted according with the standard MR protocol using axial coronal and sagittal T1, axial coronal and sagittal T2, axial flare, axial DWI and ADC, axial coronal and sagittal T1 patch set plus contrast. The acquisition parameters were long tier and short T with a flip angle of 90 degree and a soviet 21 centimeter and two V values were taken and ADC maps were automatically calculated using the inbuilt software. The data were analyzed using the SPSS, using the SPSS version pattern. Then we can see, we can see one tumor that is high grade glioma diagnosed histopathologically. We can see the disarray looking cell with cellar atypia that tumor showed high diffusion restriction on DWI and corresponding low ADC value. Another tumor that is histopathologically proven schwannoma, schwannoma no diffusion restriction with high ADC value. So, coming to the result, as we can see there is a slight male pre-reliction and coming to the age distribution including the study included 60 patients, majority belong from the 41 to 70 years age group findings. In the study, 38 percent patient had high grade glioma, 10 percent patient had lymphoma, 4 percent patient had metastasis and 3 percent patient has atypical pterodactyrate tumor and rest of the patients having meningioma, low grade glioma, schwannoma and pituitary macrodenoma. Now coming to the main finding, the 28 patients with high grade tumor had low ADC value where the 4 patients with high grade tumor had high ADC value, whereas the 5 patients with low grade tumor had low ADC value and 28 and 23 patients with low grade tumor had high ADC value. So, we can clearly see 87 percent patients with histopathologically proven high grade tumors at low ADC values and 82 percent patients of low grade tumor had shown high ADC values on MRI. So, now coming to the validity of ADC, high grade tumor with low ADC shown the sensitivity of 87 percent, specificity of 82 percent, positive predictive value of 84 percent and accuracy of 85 percent, whereas low grade tumor with high ADC value had shown sensitivity of 82 percent, specificity of 87.5 percent, positive predictive value of 85 percent and accuracy of 85 percent. So, we can clearly see the sensitivity and specificity in predicting the grade of brain tumor showing significant positive result with good sensitivity and specificity. So, now coming to the discussion part, the study included 60 patients of brain tumor out of them, 32 patients had histologically proven high grade tumor and 28 had histologically proven low grade tumor. So, the findings were the majority of the patients belong from the 41 to 70 years of age group constituted about 73 percent of study population, 57 percent were male and 43 percent were female, 87 percent of patients with 87 percent patients with histologically proven high grade tumors had low ADC and 82 percent patients with low grade tumor had high ADC values. So, WHO3 and 4 were histologically proven, WHO3 and 4 were considered to be high grade tumor and WHO1 and 2 were considered to be low grade tumor. We compared our study with few studies which shown the positive correlation between the ADC, ADC value and brain tumor reading. So, you can see that I have taken the four studies which have shown the positive correlation between the ADC value and brain tumor with an inverse relationship between the ADC value and brain tumor. ADC value, sorry, an inverse relationship between ADC value and high grade tumors. So, to conclude, preoperative accurate brain tumor diagnosis plays an essential role in selection of optimum treatment strategy as their management and prognosis are different. Through this study, we aim to analyze the potential of ADC in predicting the tumor grade by examining DWI and correlating the ADC of the tumor with WHO grade. And we found that our study is consistent with the reference studies. ADCs greater than 800 are predictive of low grade tumor with a sensitivity of 82 percent and ADCs that with less than 800 are predictive of high grade tumor with a sensitivity of 87.5 percent. These are my references. Thank you.


Hello, and welcome to the Adafruit Show and Tell. I'm Liz. I'm going to be your host this evening. If you would like to join, the StreamYard link can be found in the Adafruit Discord. That's adafruit.it slash discord in the live broadcast chat channel. Click the link and you'll be able to come into the queue to show up your project. But first, we're going to kick things off with some Adafruit folks. First, Melissa, maker Melissa. Hello. Melissa, how are you? Good. I've been working on a CircaPython installer for the CircaPython.org website. So rather than just downloading the firmware and the bootloader, it would actually go through and do all the installation for you on the website. So I wanted to show what I had on my computer at this moment. Yeah. I'll share your screen. Yeah. There is the tab there. So right now I have an open installer button and it comes up with a little menu when you do that. And I'm going to go ahead and click that. And I have this board connected to my computer at the moment. So I'm going to connect. You probably can't see this. I'm choosing it from a menu and so it connects. Yeah. Here we go. Next. And then it goes and erases the flash there. And this is kind of similar to the, is it kind of the same guts of ESP tool? Yeah. It's just like that in the back end. Yeah. Very cool. And then now it's going, it unzips the file and then starts putting the bootloader on. Right now I'm only showing the bootloader, but it's flashing that you can bind up in. And then I need to add it so it'll copy the UF 200 still. But I just wanted to kind of give you a little demonstration of what it looks like. Yeah. It's very cool. I like that folks will be able to just like find the board and just click and it'll do the thing because sometimes ESP tool could be a little intimidating for beginners. So I think this will be really awesome for folks. Yeah. Yeah. And then hopefully we can eventually add this into like the learn guide and stuff. So yeah, that's pretty much it at this point here, but it's just like a little lizard and it's configurable and maybe we can even use it like the Whippersnapper and stuff like that. Yeah, that'd be awesome. It's been really cool seeing your work on that and can't wait for our folks to get to use it. Yeah. Cool. All right. Thank you so much, Melissa. Have a good night. Thank you. You too. Next, we are going to go to Scott. Hey, Scott, how's it going? Hey, thanks for having me and thanks for hosting.  So I'm circling back to some stuff. First is the watch. My watch doesn't have anything. It's just me now. So I have CircuitPython running on my watch here. And I've had it running since August, basically, when I was on leave. And now I want to dust it off and get it actually checked in so that we're able to have other people use it. I have a second one here that I kind of haven't messed with. And I'm trying to get it working there, installing kind of wirelessly rather than using the. The secret ester pins on the back. So I've got to figure that out. So if anybody's done Nordic, if you hit me up on Discord and help me out. But then the other thing is the display on here is kind of like a sharp memory display, except it's three, three bits of color, one for red, one for green and one for blue. And so I was in there in display, I doing some like very low color work, you know, with three bits and four bits sort of stuff. And that got me thinking about yinck. Yeah, there's these seven color yincks, which are kind of weird. They're weird because it's it's not like with the watch, it's one bit R, one bit G, one bit blue. And that's kind of like gets you eight colors. But in this case, for these displays, it's like red, orange, yellow, green, blue and then black and white are your seven colors. I think if I counted right. So it means that you like this is a graphic actually designed for this display. So it looks pretty good. Yeah. And I'm turning it just because you'll get too much reflection if I don't turn it. You can use colors pop that way. Yeah. So this is kind of in the very similar places of display as. As the watch code. So that's why I was in there. And I've been thinking a lot about yinck and and all that. So finally dusted this off and this is a five point six five inch display. And Pimerone has a version of this as well. This is a wave share module. Yeah. And then it also comes in a four inch. So I got the Pimerone four inch on the way. And then it also comes in a seven inch, which is kind of so I'm kind of excited to see a larger ink as well and all colors. So to get an eye on the PRs for a ticker Python to get the sport for this in there. Excellent. I'm excited to play with that. I'm sure a lot of folks are. Yeah. Yeah. It's it's been a long time coming. Like the more was playing around with this like, I don't know, you're years ago and she like actually bought some of these. So expect to see those in the shop at some point as well. Excellent. Great. Thanks so much, Scott. Thanks, Liz. A good one. Next, we're going to go to Jeff. Hello, Jeff, how's it going? I'm good. So I wanted to talk to you because I put a new guide in the aid of fruit learning system this week. This is the mouse of the original next computer. And now you can convert this to your to run on your modern computer with circuit Python. So if you want to bring up my little overhead camera, this is the little box that I made to hold the converter. And so there's just about eight wires here. You solder them in, plug everybody in and you're good to go. But what I wanted to talk about a little bit is this is the kind of mouse that kind of broadly is called a bus mouse. And there's no not much smarts inside it. So like all of the raw information about the button, whether the button is pressed or not, or the like the motion information is coming in here and this is decoding it and sending it on to your computer. So anyway, I already took the screws out and I peaked a little bit, but let's see what's in inside here. Yeah. So we've got a couple of buttons. We've got the connector and then this is the motion assembly. It had three more screws. And I was a little surprised when I got down here. It looked a little different than what I expected. Come on. So actually that all that assembly all pulls out as one piece. OK. And so here on the back, I'll zoom down. So I would like to figure out what these two chips are. There's two and there's probably one for the X and Y. So this little guy here rolls. The ball moves against this guy here and is rotating in here. And that's got some kind of sensor that produces a pair of signals that you can decode with incremental encoder. And I'm guessing that goes to the chips U1 and U2 and then comes out. But these aren't like microcontrollers. They're just like amplifying the LED signal or something like that. Yeah. And then CircuitPython does all the rest. And I'd love for you to check out the guide. And if you adapted to run some other kind of old mouse from this era, like I think it would run an Atari ST mouse or maybe the Commodore mouse with a little adaptation. So I'd love to hear if you have an old mouse and get it to work with CircuitPython to bring it onto your modern computer. And that's what I got for you tonight. And you've done a few guides now bringing these vintage products. Yeah, I've got a number of keyboard guides. This is the first mouse guide that I did. Actually, I did a second one because you can also daisy chain it with the next keyboard. That was how they hooked together. This plugged into the keyboard and the keyboard plugged into the computer. But yeah, maybe I'll do more mice. So if you are interested in that, you can hit me up on Mastodon or on the Discord and tell me what I should do next. Just don't break the bank by telling me to get an ultra rare mouse because it should be something that other people could get a hold of as well. That's fair. Anyway, that's what I got for you tonight. Great. And when I was little, I would always see the balls in the ball and the mice and I'd really want to get it out. And so it's very sad. Oh, me too. Now it's what's going on inside. I would want to fidget with that totally. Yeah. Awesome. Thanks so much, Jeff. All right, see you later. And now we're gonna have JP play us out with I think some retro action. Hey, Liz. Yeah, first can I tell a story about mice? Okay, so I had a buddy that I worked with when I worked at Disney Animation and I had this buddy, Joe, who was an animator. We used to play pranks on each other. And one day I came back to my office, I think, from lunch and my mouse was acting super weird. So back in those days, in fact, we had like dual SGI CRT monitors. So two like 22 inch CRTs, like 1,000 pounds of monitor. And I went to do something and my cursor just started to like drift off the screen. I'm like, what is up with my mouse? And it took a minute or two for me to like look it all around here, this weird little whiny noise. And I look around on the ground like the workstation is sitting there on the floor basically behind my desk.  Joe had hooked up a pager motor to a battery and had taken a second mouse and plugged it into my computer and opened the mouse up.  And it was like, it had barely any traction. So it was like a weird slow jerky motion that was endless. So I never, I never got back at him. So that, and that was like 18 years ago. So I've been waiting cause that one was so good that I didn't really, he ended it right there. It was a really good, really good hack. So thanks, Joe. And thanks for reminding me of that, Jeff, with your ball mouse cause those, yeah, those often had like either a physical wheel that's fun or usually two wheels that would spin like a little light blocking LED encoder thing would get spun. So that was my mouse story. Yeah, so, so I wanted to share a screen here that I didn't set up. So let me, let me add, I'm gonna try two different things. So let me try this one first. Okay, so the Nintendo entertainment system emulator running on Pico with HDMI, actually DVI and audio output through an HDMI shaped connector and SD cards. So this is a project that Frank Hode Makers put together and it was forked off of a couple other iterations of this, but his added the SD card support, I think, and he put together two versions. One runs on a Pimeroni, and he put together two versions. One runs on a Pimeroni base that has some of these things built in and the other one, he just put it on a breadboard and used the Adderfruit add-ons for DVI breakout and SD card breakout. So the ROMs that you're gonna play on this Nintendo emulator go on the SD card, which is really cool actually, cause it makes it easy for someone who's not technical, if you give a gift version of this to someone, they can just power it off, put a ROM on the card and play. Yeah. This, I've got it running back here, which you won't be able to see too well. And I picked Kirby, which probably doesn't have enough contrast to look like much of anything, but there it is playing. So it's playing, I think it's 64480 over HDMI port on this old TV, LCD TV. But the innovation, the thing that's really cool is that this is now running with a real NES controller instead of a modern controller plugged into USB. And this is thanks to Phil B. So our own paint your dragon, I asked him, hey, is there any chance you could look at, while you're fiddling around in there and checking out the code, what do you think it would take to use the shift register as three wires of like data latch and clock as well as ground and power. Those are what are in the end. I'm gonna probably break things by unplugging it while it's live, but that's the end of the controller. It's a seven pin connector. Two of the pins are reserved for other uses, like with some of the joysticks that have weird other support and probably some of that robot Bob stuff uses it or Rob uses it. But this, he was able to get it working. And so no longer need the OTG connector and the USB controllers were real pain to figure out how to get them working. So it's like very specific to like just the dual shock from PlayStation, dual shock four and the dual sense. That's it. You're gonna try to plug something else in, forget it. Generics don't really work in that USB game pad descriptor world. They're all super specific. So that was win number one. Two, those are both like $40, $50 controllers. You can buy used originals for 10 to 20 bucks on eBay, less if you find them at a yard sale or a thrift shop. And there are clones of these that cost like $2 that will also, I'm sure they'll also work as a well-known protocol and convention. And you're able to get these things, which are the connectors forum on AliExpress. I got like 10 of them for six bucks or something like that. I developed a little PCB to put the original three things I needed plus a switch on there. Now I'm developing another one that'll have a spot for the NES controller. And since Nintendo is awesome, they made it so that the SNES controller was essentially backwards compatible and Lamorra was just discussing this. I think it's 16 bits, but the first eight bits that this sent are the ones that the NES wants. So it just describes the rest and it actually worked. Yeah, so I plugged one of these in through just a bunch of wiring, but I got a hold of some of these too, like a couple of bucks. And I'm just measuring those carefully. There's no footprint I could find, but I'm measuring those carefully in building Minerino and then adding footprints to the board. So I think I'll be able to fit both of these on here. You can plug them both in at the same time if you want. You might do that for like accessibility stuff if a couple of people want to have like one person's on the D-pad and the other's on the A button so that you can get in a fight and hate each other or something. That's, I think, possible. I don't think there's anything bad about that. I was gonna do a selector switch, but it turns out you kinda don't really need to. You can just plug them both in. So that's what the state of that is. And then I just wanna share the other screen here. One second, I'll change what I'm sending. Let's see. Share screen, window. So I've been putting together these in fritzing. So for some reason, I've become enamored of making these PCBs in fritzing. UI on it is easy to kinda get into when you haven't done in a while, which is not the case for me with Eagle. I've used Eagle in the past and anytime I don't use it for a while, I absolutely immediately forget how to use it because it has very kinda old-fashioned UI things about it. Maybe that's changed with some of the newer versions of it. But anyway, I've been doing these in fritzing. So I started out on a breadboard. That's what this project looked like and I had to make up some sort of bogus stuff here to plug in my NES controller, put together a schematic for it, and then start laying it out. These are the sort of made-up things. I'm just using holes and putting them where I've measured they need to be, but that so far seems to work pretty well. I've printed these out and they seem to line up. I'm making a little breakout header there so that you can still plug weird stuff in without needing the exact controller port. And I still have to add the SNES controller. And then let me just flip it over to the bottom real quick. And the other thing I kinda didn't really realize is this is not that difficult to put pretty fancy silkscreens on in fritzing. Let me see how it looks. It looks nice on the front there. Yeah, oh, yeah, right. You there's, I put a logo there, right? Yeah, so that logo, I presume it'll look nice when I get them made. I haven't tried yet with a fancier logo on these. Let me just flip over to the bottom silkscreen and I gotta hide the top stuff. Let me see the top silkscreen. So this was, I should probably change it because this is just like a Google search for someone's ripped icons from sprites from a game. I'll probably find something else that isn't someone's. But what I did was I just took it into Photoshop and dithered it so that I could get some, it's really just black and white, but there's a lot of good dithering tools in Photoshop to make some shades in there. So that's what it looks like right now. I might end up changing that. There's the URL at the bottom there and I'll put it in the chat, which is the GitHub page for this SNES emulator for Pico. And once I get this PCB made, this new version I'll post it up to that same, to Frank's GitHub, so it'll all live there. It's very serendipitous that you'd left that space out of those intentional notes that Ben had said. Yeah, I totally was like, I don't need to make this as small as possible. I'm just gonna make it kind of rectangular and I bet I'll use this space for something. So I think those will both fit, hopefully not or I'll rearrange stuff a little bit, but yeah, that's the state of things. And it's a nice, you can press select and start at the same time. Oh no, it doesn't love me anymore. Oh wait, let's see, let's see. Does this recover from a unplug, re-plug the question? Hey, it did. Okay, yeah, so this has a little file loader. Oh, that's great. You can go in and start up a new game. And as Phil was explaining, it essentially reads, it launches that menu system thing, waits for you to pick something. It writes the name of the ROM you've picked to a text file and then it kind of reboots the machine and checks for that file name and that's the next thing it launches. And some stuff looks great on it, even on, I noticed even on a, this is a progressive display, but this emulator has added fake scan lines that on some games look really nice, look fairly convincing and a little less blurry than Nintendo's own Android emulator they put into a little mini SNES. So some of the games have a little blur to them, but some of them look nice and sharp. So I've been impressed. You can put that on your big LCD or plasma it actually looks kind of nice. That's awesome. Yeah. And you have your show tomorrow at 4pm Eastern? Show tomorrow, come on by, I'll be hacking more on the see and say. I've got the vintage style, the retro style but modern see and say, Fisher Price toy that I've been replacing its innards with some circuit Python stuffs and I've got some of my own city sounds instead of the usual farm and barking dogs. Actually, I still have barking dogs. That's very city, but we're garbage trucks now. So. Excellent. All right. Well, thanks. Yeah, thanks, come on by. Thank you. Have a good one. All right. That is going to do it for show and tell tonight. Thank you everyone for showing your projects up next in just nine minutes right here on the YouTube channel is going to be Ask Engineer with the more PT. And until next time, have a good night.


Family Theater presents transcribed Star of Wonder with Pat O'Brien as host. Mission with Family Theater presents Star of Wonder. To introduce the drama, here is your host, Pat O'Brien. Thank you, Tony LaFranco. Family Theater's only purpose is to bring to everyone's attention the practice that must become an important part of our lives. If we are to win peace for ourselves, peace for our families and peace for the world, Family Theater urges you to pray. Pray together as a family. Tonight, Family Theater takes great pleasure in presenting Star of Wonder, featuring Francis X Bushman, Norman Field, Herbert Rawlinson, and Cliff Clark, with Jill Oppenheim as Evie. Once upon a time in a great observatory on a pine-covered mountain in the western state, there lived three wise old men. There was even Joe, who had spent his entire life in the study of the Saturnian rings. The thickness of these rings is very small, perhaps even less than 10 miles, nowhere else in the universe. And there was Otto Schwartz, a recognized authority on lunar craters. The moon's surface offers us astounding evidence of the effect of widespread volcanic fests. And finally, there was Walter Lethem, whose monograph on the atmosphere of Venus was an astronomical landmark. Further confirmation of the supposition that the physical surface of Venus is the top of a cloud bank is evidenced by the color of the... There they were, the three of them, isolated in the lonely mountain top observatory, each tolerating the other two, no more. They knew about Saturn and the moon and Venus, these three wise men, but they had forgotten about people, about love, about Christmas, and then it happened. Even had gone for the mail that morning, and when he returned from the half-mile hike to the box... Oh, I ask you, Walter, how was I to know that it was your notes, a note scrap of paper? A scrap of paper. Six months' work and you use it to light your cigar. Why do you have to smoke the smelly things in the tower room anyway? This pleasure.  I am sorry. I will help you gather the data again. You will. And what makes you feel that you are qualified to help me assemble material on the atmospheric changes of Venus? Walter, stop! You're like two children. Why must there be this constant bickering? Oh, even. You're back. Any mail? Yes. The Journal of Astronomy for you, Walter, and the Christmas Circular for you, Otto. Christmas Circular. Where do the days go? To the end of another year we are coming. I've been waiting for the Journal. This is the issue in which God had promised to make a fool of himself. The air must be chilly this morning, even. You look flushed in the face. We have snow before the week is out. Otto, Walter, there was one other thing in the mail this morning. Another thing? What? Not a letter from the trustees, I hope? The letter was for me, but it affects us all, so I thought I should read it to you. It's from a woman named Farrell. She lived next to my sister in Orange, New Jersey. She writes that my sister has died. Oh, I'm so sorry, even. I did not know you had the sister. I thought you were alone, like me. She was a younger sister. I haven't seen her for years. Twenty years or more it must be. It's hard to grasp a death when it happens far from us. She was married, this sister? She was a widow. Her husband died several years ago. If there's any work of yours that I can do today, even, wait. There's more. More? She left a child. A child? A daughter named Eve. How old is the girl, even? Ten. I've never seen her. We didn't correspond, my sister and I. I suppose I should have kept in touch, but... It's easy to forget up here. I hope the child is well provided for. She isn't. The girl has nothing. No one. Even. A little money I have saved, if it will help you... You can count on me, too. Very generous of you both, but it isn't money that's the worry. The child has no home. Home? Surely, even. You didn't think. I know how you feel, but it was my sister's last request, according to this feral woman, that Eve be sent to me. Bring a child here to the observatory. I know how it sounds. A ten-year-old girl here. Even this you cannot seriously consider. Why, it's preposterous. The notion of keeping this girl in the observatory is unthinkable. I agree with you, Walter. We can't keep her here permanently, but until I can make other arrangements. Children have no respect for routine. Life here will be intolerant. Walter, for a little while, until Eve makes his arrangements. Oh, so you're both against me. Not against you, Walter. It won't be an ideal situation, I admit it. But until I can properly place the child. Very well. As long as we understand that this is a temporary arrangement. Well, it may take me a little time to find a school that will accept her. Why should that be if we're prepared to pay the price? One thing I forgot to mention. Eve is blind. Even? By the mailbox on the road. Oh, we're still half-mile from the observatory. Are you sure you feel like walking it? I'll be fine if we go slow and you hold my hand. All right. The trail's rather steep. There are tall pine trees here, aren't there, Uncle Even? Yes, they're pines. They surround the observatory. I can hear the wind walking through them. Is the observatory tower very high, Uncle Even? High? Well, yes, I suppose it is. This is a very high mountain, and the tower is almost 100 feet above the summit. So close to the stars. Am I going too fast for you? Oh, no, no. I'm all right.  Your head covered with stars. Well, that's not quite the way of it. Eve, you know, there are two other men at the observatory with me. The three wise men. You know, we haven't had much experience with younger people, so if you'll try to remember that, I'm sure we'll all get along very well together. I'll remember. Uncle Even, you haven't seen the wise men's star this year. Yes, have you? No, no, nothing. Careful there now. Don't slip. It's quite a drop off the trail here. I'm all right as long as I have your hand, Uncle Even. Up here, I feel so much closer to the stars. So much closer. Such a strange one she is. Not an ordinary little girl at all, Walter. What do you know about ordinary little girls? She says so little, and yet there is a feeling when she's in a room as if she were talking, seeing things that cannot be put in words. Oh, I do not make good sense. That can't be blamed on the child. I wonder if Even is doing anything about a school for her. He has, I think, written some letters. Otto, I don't mean to let him forget that this is a temporary arrangement. I don't think he will. Walter, has she asked you about the star? The star? What star? There are millions of stars, and why should she ask me about one of them? I don't know. Several times she mentions it to me since she comes, as if I should know of it. Oh, it's some childish game. Where is she now? With Even, I think. I've not seen her since supper. She knows her place. I'll give her that. Doesn't intrude. All the same. This won't be a fit place to work until she goes. Which of you had my slide rule? I use my own instruments. No one else's. Maybe I use it, Even. But I put it back in the case, I'm sure. Anyway, it is a week or more. Well, where is Evee? Evee? With you, we thought she was. And I thought she came in here after supper. Where do you suppose she is? Her room? The tower? Check in her room, Otto. I'll look up in the tower. Doing up here. That circular staircase. You might have fallen. I wasn't afraid. Not busy. I wanted to be close. What star? You should be up here alone with all this equipment. These telescopes are set. You might have pumped into one of them and spoiled everything. Uncle Even, it's only a week now till Christmas. The star should be in the sky. Christmas? What star should be in the sky? The star that the wise men followed. The wise men. When Mom used to tell me the Christmas story, I think how lucky you were to be able to see the star so plain. Our Christmas story, Evee. You don't still believe in that, do you? Believe it? They couldn't see the star at home because it was always so much smoke. Up here? Well, I can feel that I'm close to it. If I could see, oh, I bet I could show you just where to find it. That's a story for babies. You've grown up, Evee. You'll find no such star in the sky. And you must promise me not to come up here ever again. But Mom said that the star... I've lived all my life with the stars, my dear. Don't you think I'd know if there were such a star? I don't want to hear any more about it. If you'd only look... I'd help you down to beddy. If you're going to stay here with us, you'd have to learn to live our way. Take our word for the things we know.  Yes, Uncle Eben. I'm sorry that I spoke to you so... so roughly, but it's for your own good. For my own good to forget about the star in the east to me? Of course. There's no time for such stories here. All right, Uncle Eben. The sooner you forget them, the happier you'll be. The happier we'll all be. When he had privilege called the wise man, inquired of him diligently what time the star appeared. And he sent them to Bethlehem and said, Go and search diligently for the young child. And when you have found him, bring me word again. That I may come and worship him also. It's getting late, Evee. Don't you think you're very good... Yes, Uncle Eben. There's just a little more about the star. Let her finish, Evee, but she reads it good. When they had heard the king, they departed. And lo, the star which they saw in the east went before them, till it came and stood over where the young child was. And when they saw the star, they rejoiced with exceeding great joy. You were hardly touching the braille, Evee. I've read that part so many times I know it by heart. Oh, I'd give anything if I could see that star that the wise man saw. Evee. Oh, I'm sorry, Uncle Eben.  Who was like us? The three wise men. They probably lived in a place like this and watched the stars. Same as you. Just think how excited they must have been to see that new star in the sky. It's almost 10 o'clock, Evee. No scientific record of their discovery. Yeah, take my hand, Evee. Oh, I do wonderfully well by myself now, Uncle Eben. I can go almost any place in the observatory and never stumble once. Good night, little one. Good night, Uncle Otto. Uncle Walter. Good night. Tonight I'm going to dream about Christmas. Put out the lights down here when you're through. I'm going up the tower. It's good to turn your eyes to the stars. They don't change all in their places, just as they've been for millions of years. Star in the Easter child's story. There's no such star there and never was. Child is to be so upset. It's the girl. She must go. As soon as the holiday's over, I must find another place for her. And as soon as the holiday... What was that? In the tower of something forest. Yeah, Evee must be up there. I thought you told that child. I did. She's disobeyed me. But don't stand there. Let's see what she's smashed. Big glass thin compass from Switzerland. Oh, and a valuable instrument. Now look at it. Junk. Nothing but junk. You promised me that you'd never come up those stairs again. What did she mean the compass had never been there before? How many times do you come to this tower, Evee? Every night. What in the world would you want to come up here for? The stars. Get up here. Well, I just felt sort of... Well, sort of lonely since I came to live here. And the star was a thing I could hold on to. I told you once before, Evee, there was no such star. Oh, get set. I can see, Evee. I've looked through the telescope night after night all my life. And there is no such star. Oh, I can't believe it. I can't. I'll leave it to Walter Tuato. Is there a star in the east, a new star, that comes only at special times of the year? Of course not.  Tuato! No. No, there is no such star, little one. Now, how do you believe me? Oh, what? Go to your room. Should one of us follow her, Evee? No. No. Let her alone. The weather's closing in. It'll be snow before morning. Visibility is limited. Yes. Visibility is very limited. I sleep. I can't. I sleep. I've got to make sure she's all right. Is that you, even? Oh, Otto. Yes, I couldn't sleep. I thought I'd look in on Evee just to make sure she's all right. It's snowing very hard. Otto, the door to her room. It's standing open. She's gone, even. Look at the bed. It hasn't been slept in at all. She can't be gone.  She's run away outside in this storm. Oh, no. Even what have we done to her? We've got to find her, Otto. We've got to find her. By that tree. He against it. Evee. Evee. It's her. Right now, Evee. All right. Otto. Walter. I found her. I found her. Is she all right? I wish I could tell her that she was. She's fighting pneumonia, exposure, shock. But she, she will be all right. She's a very sick youngster. I wish I could take her to the hospital. I'm afraid to move her. We'll take care of her. Just tell us what we must do. Well, I've given her a shot of penicillin. I'll leave some medicine here and I want you to force liquids on her. I'll be back in the morning. Surely there, there isn't any cause for alarm, is there? Just follow my instructions. I'll see you in the morning. It's all right. She's not rallying. If anything, she slipped since yesterday. We followed your instructions, doctor. She took the medicine, we forced the liquids, and one of us was with her all the time. Usually kids her age kick right back. React in less than 24 hours. But she's not fighting it at all. Anything that we can do to help her, just tell us, doctor. No, we haven't quit yet. That's not going to be a very merry Christmas for the poor little kid. This is Christmas Eve, isn't it? I'll be here in the morning. If she should get worse, you'll just have to try to get through to me. If she gets worse, she doesn't want to get well. She's not fighting at all. And it's our fault. The only thing she found here to love, we tried to take from her. She believed in the star. She really believed. Do you know until she came, I had forgotten that story? We had nothing to believe in, so her faith angered us. The star, did you see the star? Evened, do you think if we took her up there? To the tower room? The doctor said it was dangerous to move her. But if she could believe again, well, get that extra blanket. Otto, help me. We're going up to the telescope. Evee, we're in the tower room with the big telescope. Evee, it's Christmas Eve. We thought you might like to be near the star. You don't believe it, sir. You don't believe in the star. Tell us where to look, Evee. We want to believe. Help us. Where will it be, Evee? You want to believe? Yes, yes, Evee, we do. Help us, Evee. Tell us where to look. It was in the east, and it was very bright. If you believe, I believe, you must be able to see it tonight of all nights. Let me see. You're looking in the telescope? Yes, I am. I don't see anything yet, Evee. Keep looking, Uncle Evee, keep looking. I see it. Otto, won't I? Look, it is there, a great shining star where there's never been a star before. Let me see. It can't be there. It can't. And still it is. A beautiful star, Evee. A magnificent star. Star of wonder, star of life. You believe me now? Of course we do, Evee, and you've got to get well. We need you. The three of us need you, Evee. You need me? Yes. Yes, we do, Evee. She's going to get well, aren't you, Evee? Yes. Yes, I'm going to get well.  Our forehead is cool. I think the worst is over. Merry Christmas, Uncle Eben. Uncle Walter and Uncle Otto. Merry Christmas, Evee. Yes, Merry Christmas, Evee. Merry Christmas. Merry Christmas, little one. Best you should take her back to bed, Evee. Yes, I will. And when they saw the star, they rejoiced with exceeding great joy, with exceeding great joy. This is Pat O'Brien again. During the season of the year, there's a lot of praying going on, and that's a very good thing. And since some of these prayers are set to music to form carols during the Christmas season, it gives us an opportunity for a musical illustration of what we mean when we speak of the beauty of family prayer. With Mr. Zimmerman's help, we'll use the family of stringed instruments in our illustration. We'll start with the father and then the mother. Then let's say there's one son, one daughter. Pretty little thing, isn't she? Now, each of the members of this musical family is capable of carrying the melody of this beautiful Christmas hymn without any help from the others. But listen to them play the same melody, not as individual instruments, but as a family of instruments. See? You see how the harmony adds beauty? How the melody gains new importance? Family prayer is much the same. But prayer is music to God. And since we were created by Him, and since it is through Him that all good comes to us, then shouldn't we strive to make our prayers as worthy as possible, as beautiful as possible? There's really no doubt that the members of the family praying as individuals do make music in heaven. And they pray together. Well, then they make a concert. Is one other argument in favor of family prayer? It's a promise that family theater uses for a slogan. The family that prays together stays together.  The script was written by John McGreevy with music composed and conducted by Harry Zimmerman and was directed for Family Theater by Joseph F. Mansfield. This is Tony LaFranco expressing the wish of Family Theater that the blessing of God may be upon you and your home and inviting you to join us next week for Family Theater. Join us, won't you? Family Theater transcribed as broadcast throughout the world and originates in the Hollywood studios of the world's largest network. This is the Mutual Broadcasting System.