We have rollers, we told you that we all in, you fold up, it's all over, those up in the culture, the way that we live, every day of pay, we told you that we gotta win, you know us, we play the rush, I'm all in for this life, gotta chase the sun, I keep a straight face even when I'm under the gun, yeah. Anthony, I want to start by asking you about the day you had against the Houston Texans. You had over 100 receiving yards.  Yeah, I mean, I'm just excited to be able to find a role for the offense and be able to be in the spot when Ryan needs me. Yeah, just so happened I got a couple extra targets this game and I mean, yeah, I was excited to just have a big role in the win. What is it about Ryan Tannehill's leadership that makes this team so successful in high pressure situations? Yeah, I mean, he does a great job, calming everyone down and just having that trust in the huddle that we know we can win the game no matter what the situation. Yeah, everyone's in there trusting each other and just executing what we do in practice and what we've done in the past couple of games and we know we can come out on top. We just do the right thing. How does your preparation throughout the week, whether it be in practice or meetings, help prepare you for those high pressure stressful situations? Yeah, I think Coach Rable does a great job of kind of going through as many situations as he can. I know there's millions of different situations, but he does a great job giving us time and practice to watch it in film or kind of give us practice reps on different situations, whether it's X amount of time on the clock, timeouts. Yeah, we feel like we've run these similar situations in practice and we just go out there and execute. Titans are a major part of this Titans offensive scheme. What does that say to you about Arthur Smith and how much he trusts all the guys in that room to get the job done? Yeah, I think Arthur coming from a Titans position and coaching a lot of us prior to being the coordinator. I mean, yeah, he feels like he has trust in us and yeah, Todd did a great job stepping up at that Titans coach role. He just gets us in the right play, able to coach us to know what we got to do, know how we can execute, gives us all the tools we need. Yeah, if we're just able to keep being productive, yeah, just keep coming our way. The Titans have come out on top in a lot of close victories. As a player, how much confidence does that give you in the entire system that you're running that this stuff actually works? Yeah, exactly. I mean, we've seen the time and time out game after game that we've been successful and able to come out with the win. So, I mean, we're on the sidelines and the defense is out there, the offense is out there. We're cheering and we're have faith that they're going to be able to get the job done to have us execute and win the game. Does it take a little bit longer to get over a close victory? Do you need a little bit longer to celebrate, longer than maybe just 24 hours? No, I think we have a great mentality in the locker room where we're just looking at one game at a time and after Sunday, we win that game. I mean, we're looking at next week and just kind of focused on that. We know not to look in the past and not to get too high, not to get too low. How good does it feel to be 5-0 right now? Yeah, it feels good. I think we put ourselves in a good situation, but there's still a lot more games left in the season and we got to keep improving each week. What sets this 2020 team apart from some of the other Titans teams that you've been a part of? I think there's more confidence and trust. I mean, we've been running the same offense and similar defense schemes and just being able to trust each other and communicate and just have that type of commodity on a team is just give us all the confidence in the world.


Our next session is clinical evidence in genomic medicine sustainability. We'll have talks on the state of science and gaps from Jonathan Berg and Roger Klein. First will be Jonathan Berg from the University of North Carolina at Chapel Hill. Thank you. All right. Well, thank you for inviting me to speak. I've really enjoyed hearing about Ignite and everything that's going on.  And there's quite a lot to talk about. So I'm going to try to focus on just a few things here. You know, I think this is probably the key issue that we face in our society, which is the health care spending. And I think that largely this is why genetics is getting picked on as the new kid on the block, as Mark Williams told me this morning. You know, the technology that we have to use is being increasingly scrutinized. And much of that is probably because of the perception that it is technology that drives health care costs. And so that's natural for third-party payers to want to get a handle on, right? What are we doing? Why are we doing it? What are we hoping to accomplish by it? And I think we need to meet the third-party payers and other stakeholders in that space. And we can't expect that we're going to be exempt from evidence of utility. So this graph, I've sort of modified from something that I saw David Bienstra present at an IOM meeting, a workshop a few years ago now. And I've seen versions of this in different places, and you all probably have. And the idea is that if you just map things in terms of whether they cost you more or less and whether you get better outcomes or worse, then you can sort of map things out and say, well, these are the things that cost more and give us worse outcomes. We shouldn't be doing that. These are the things that give us better outcomes and cost less. And we all hope that genomic medicine will give us those types of outcomes. But the question is, really, can we achieve it? There's going to be some things that actually will give us lower costs but worse outcomes. And we could think about whether we'd want to use those if resources are scarce. If it's not that much worse and it's a whole lot less. So we might want to think about those things. But probably most of what we do is going to end up in the costing more and maybe giving us some better outcomes. And we need to address the fact that we do want to use the technology. And the question is, can we afford it? And does it give us the cost effectiveness we need? Obviously, this is the real no-brainer. These ones up here are actually difficult to change in medicine once you've got physicians established with practices. They don't want to change their practices even if it does turn out that they're worse outcomes and more expensive. It's pretty difficult to convince the public that they should have less, particularly if the outcomes are going to be a little bit less. And this one over here really depends on the stakeholder and what they value in this overall value proposition. So I think we're so accustomed to seeing this ubiquitous graph down now to about 1,000K per genome that it really seems intuitively obvious that we should be able to use whole genome sequencing clinically. That is why we're all in this field. But we still have to address the cost benefit, right? There's the cost of interpretation that's been mentioned. It's not the million-dollar interpretation as some sort of hyperbolic statements have made, but it's definitely more than zero. And the cost of downstream interventions are definitely going to be more than zero. So somehow we need to address the overall cost of genome sequencing and other genomic approaches. And we have to understand the net outcomes and sort of how effectively we can achieve those outcomes with sequencing. So what the evidence is for genomic medicine depends on who you ask, which I think is really important that you all have engaged stakeholders and that's going to be a main theme that I talked about. But it's also understanding what their perspectives are and really what they value in this process. And how much certainty is required to be able to make a decision about whether something should be used clinically. So these implementation studies are clearly necessary. We have to understand how to put things into a clinical space when there are all the barriers that we've identified. It is important that these need to be proven to be useful in order for the uptake to be maximal. But really the sustainability to me depends on convincing other parties involved, whether that's a healthcare system, insurance providers, FDA, etc., that genomics is effective in what it's trying to accomplish. So there have been some efforts to sort of engage stakeholders and think about what their perspectives are. And I like this way of looking at it. Again, Dave Vistra's on this, so you might have probably already invited him. He probably couldn't come, which is why you invited me. But the idea being that if you have some information about the risk and benefit of a particular application, and you have some level of uncertainty or certainty about whether it is favorable or not. That you could actually sort of get some consensus around how to use these things, how to develop them, whether you could use some evidence development practices to get additional data. So I think that this is the sort of work that probably needs to be done more to really understand at many different levels with stakeholders what kinds of evidence they need and how they could help us to generate it. So which outcomes matter? So ideally you want to get direct health outcomes, right? That's what we're in this business for. We are in a medicine field and these are the things that matter. But for physicians you could also imagine that just simply being able to tailor and improve management might be a reasonable expectation. And especially for our patients with very rare disorders, even if there are no evidence based guidelines or other sort of clear things to do, we can at least use our best clinical judgment to treat those patients as well as possible. And the idea that for patients and families there may be some intrinsic value to understanding the diagnosis, which is clearly also including what the recurrence risk is in the family. So I recently came across the hierarchical model presented by Frybeck and Thornberry, which I think originally was designed for imaging tests. I think is highly relevant to what we do. And they describe several layers of efficacy, if you will. So there's a technical efficacy to a test that really deals with its analytic validity, does it actually tell you, give you a correct assay in terms of the genotype, whether it gives you an accurate diagnosis and coupled to that, whether it helps the clinician with their diagnostic thinking, which I think relates to clinical validity. So in other words, if the physician is faced with a number of possible differential diagnosis questions, does the test help them narrow that down, exclude things, or include things? Does the test lead to therapeutic efficacy? And this is not necessarily a utility, but does it actually allow the physician to make a decision about treatment, whether or not that actually has any benefit to the patient? You also have a patient outcome efficacy, which is a bit of a higher level there, which I think falls into the clinical utility category. And then at the very top, on this case in the bottom, the societal efficacy really does the cost of healthcare change. Do you get a more cost-effective outcome with this test? So I think these are useful ways to think about what we do in genomic medicine. And just as a simple example, I sort of was thinking about cystic fibrosis. So you have a child with a diagnosis. We know what it is. So what chloride test was positive, we know the diagnosis is cystic fibrosis. So really is genetic testing needed? And you could argue that it's not if you have a clinical diagnosis. But if it is, what test would you do? And should that be covered by insurance? And so thinking about the hierarchical efficacy, clearly the genetic testing modalities we have for genotyping and sequencing of the cystic fibrosis gene are quite reliable, quite accurate. The establishing a specific molecular lesion in this particular patient might not actually help your diagnostic thinking if you just find out the patient is homozygous for the common Delta 508. Doesn't really change the clinical diagnosis any. So you could argue that, well, that didn't really help you very much because you already knew the clinical diagnosis. But if there was something that you could think about in terms of enabling different decision-making about treatment, for example, using some of the new drugs like Lumicaftor and Ivacaftor, which arguably are coming on board and are facing physicians have to face this decision of, do I try this drug? Well, we know that these drugs only work with certain types of genetic variants in the cystic fibrosis gene. So in fact, doing the sequencing and identifying the specific molecular lesion would alter therapeutic efficacy and it might even improve patient outcomes if you consider the data, the early data on these drugs. And so conceivably, this might alter the cost of carrying for cystic fibrosis patients. So going back to my questions, is genetic testing needed? I would argue yes, because we really want to know whether this drug combination is a possible therapy. And if so, what would we do? You know, and I put out here the exome is clearly an incorrect answer because you don't need to do a whole exome or a whole genome sequence to understand what the CFTR mutations are. But you could imagine a different set of conditions where there was a higher range of genetic heterogeneity and you really needed to specifically identify the gene. Should it be covered by insurance? You know, this is where it comes to the value in the economics, the cost of the test, the cost of the drug, the nature of the health outcomes. You know, the early data suggests that you can reduce hospitalizations by one third in these patients. Do we consider the cost of the drug at $259,000 a year to be affordable? It's a societal question, but these are the types of things that providers, the third party stakeholders, are going to have to make decisions about. Just as a brief thing, what about the reproductive implications we talked about, personal utility, being able to know for family reproductive planning? I think the real problem with this is that there's no defined measures of utility in that context, and every family is going to have different uses for the information. And so stakeholders are going to arguably view these differently. And I don't think this is an incorrect assessment by payers that this type of information may not be worth them paying for. But these are the sorts of things that we need to be able to communicate with stakeholders about. So getting to the gaps, I think stakeholder engagement, and as I was putting my talk together, I learned about the Ignite stakeholder engagement. Workshop wasn't able to attend, but had someone here told me a little bit about it. And it sounds like this is a very, very good first start. I think we need to conduct our engagement with respect to defined clinical scenarios. We need to be clear in communicating the population that we're interested in, the tests that we're interested in, what we're doing it for, so that the stakeholders understand the clinical context. We need to understand what they value. And this could be anywhere from patients to providers to health care systems to payers about different outcomes of genetic testing. We need to understand the evidence that they need to make decisions, understanding that this may be difficult for them to tell us in advance. But if we understand those things, the studies can be designed with very specific outcomes in mind that provide that evidence that really directly addresses those requirements. I don't think that this means that we should completely ignore the other important scientific questions in our field. One example would be how to deal with secondary findings or how to understand the penetrance of these conditions and these sorts of things. But we have to frame our studies to convey our results to these different stakeholders. I think evidence synthesis is a big gap. Just as we need the databases of genes and variants at ClinVar, and that's a somewhat self-serving statement since I'm involved in that project, I think we also need to have systematic collection, curation, and evaluation of genomic studies. And I think I heard that mentioned in the stakeholder summary that somehow understanding how to organize that information, design something in collaboration with different stakeholders so that we structure information that facilitates the review of all of these studies that we're doing, make it publicly available, have it curated by experts, make it transparent so that everyone knows what evidence the stakeholders are looking at, and then we can also design our studies for maximal impact in that area. So just to kind of summarize briefly my take-homes, technology and health care costs are a big issue for us. We just have to tackle it head-on. We definitely need to understand what stakeholders value, what evidence they need to see to support use of genetic testing, genomic testing, in different contexts, and be able to really produce the relevant evidence that'll tackle those topics. So, thank you. Thank you, Jonathan. Next we have Roger Klein from the...


Hello, my name is Monika Noriega and I work under the Department of Operations and Emergencies and I work with the team that has been leading the efforts to ensure the GBV prevention, mitigation and response is an integral part of all IOM crisis operations. This means working towards achieving that all crisis-affected persons, but especially women and girls, live free from GBV. For the past four years we've been working to ensure that IOM staff have the skills, the knowledge, the tools to properly do this, but it also means that we've been working to create the structures to ensure that the safety, dignity, well-being and equitable access to services for women and girls is prioritized, integrated and coordinated. Two months ago we took a very exciting step and the organization put its commitments on GBV into this tool, which is the GBV in crisis framework. We're very proud of all the work that IOM is doing on GBV and we're excited to see how more and more missions are putting these commitments into practice. So we want to take advantage of the 16 days of activism to remember the challenges that women and girls face in emergencies. We want to keep survivors in the center because that's the inspiration for all the work that we do and we want to honor some of the colleagues who are working to support them, who are working to mitigate GBV risks and who are working to address its root causes. So we hope that you will be as inspired as we are with all these examples and we hope that you will join us to drive more change and to do more to address GBV in crisis.


Imam towards the end of the sermon he says I'm surprised at the one. Now you'll be a little bit shocked to hear this from the Imam but will elaborate by what he means. The Imam says I'm actually surprised at the one who sleeps well at night not feeling anxious whatsoever when heaven and hell are the destination we're going to. What does the Imam mean by that? So we know that anxiety is not good obviously who wants to be in a state of anxiety but when you're approaching something serious let's say tomorrow is the day of the interview that will determine your career or tomorrow's the final exam day or you have a very important trip tomorrow honestly when you sleep at night how do you sleep? Yes maybe you could sleep well but see there's a level of anxiety right? Why? Why is it that if tomorrow is your interview and you're prepared you're fine you're prepared you know what you're doing. Why do you feel some level of anxiety? Because you're serious about that appointment right? You know how important it is. There is a healthy level of anxiety brothers and sisters there is. Yes sometimes it becomes uncontrollable it becomes a psychological disorder needs to be treated but some level of anxiety the Imam says at night when you sleep be worried about next day in terms of the good deeds that you're going to commit. Don't say yeah today's just another day I'll go about my lifestyle and my habits and a lot of them are bad habits and waste time. No when you sleep at night be concerned that I have this journey ahead of me am I prepared for it or no? In other words the Imam says take it seriously. If you sleep not caring whatsoever that one says you're not taking seriously. The Imam says I'm surprised at the one who sleeps without any concern about this journey. Some level of concern and anxiety it's good it keeps you in check that way you wake up in the morning you're like I have a goal today I'm not going to waste a single minute every opportunity to do a good deed I'll take advantage of that opportunity because I know there's a big journey ahead of me yes Allah is merciful no doubt about that my dear brothers and sisters but remember that race you're racing let's say with 70 billion people don't you want to be the first in the race the second top ten top hundred top thousand let's even say top million you're lucky if you make it to the top million out of 70 million right the Imam says look if you want to be in the top one thousand or top one million you have to be prepared yes Allah is merciful he forgives as much as there is room for forgiveness but the Imam is teaching you when the race be a winner on the day of judgment it's a marathon we all want to win right if I lose in the race or I don't really do well I'll be disappointed in a small worldly late race we see we get disappointed don't we now imagine the race of the hereafter the ultimate race the final race and it's only one race the Imam says be a winner in that race but the way that you can do that is in this world as long as you still are alive Allah has given you the resources to do that which is right to take advantage of these numbered days in this world be good to your family to your parents to your children it's not worth it be good to your loved ones to your friends be charitable and remember this Quran this Quran will be the greatest source of light on the day of judgment the hadith states on the day of judgment and it's a difficult day there are many you know checkpoints we have to go through many many different passages we have to go through and remember that final passage which is the bridge of Surat which the hadith describes it as narrower than what than a thread and sharper than a sword we're all gonna cross that now the Holy Quran tells us that bridge will cross over what what does it cross over to get you to heaven yeah it crosses over hell the hadith says judgment for those believers who were good with the Quran they read the Quran they studied the Quran and they more importantly implemented its implementation that counts somebody could read it like a parrot that doesn't do them any good no to implement the teachings of the Quran on the day of judgment this Quran will transform into a beautiful figure the hadith says on the day of judgment the person you know has anxiety it's a difficult day look at Surat Al-Hajj Allah describes it Allah describes the day of judgment in Surat Al-Hajj it is a difficult day such that a woman who's breastfeeding her child the Quran makes this description brothers and sisters these are the words of God we should be familiar with the words of God يَوْمَ تَذْهَلُ كُلْ مُرْضَعَتٍ عَمَّا أَرْضَعَتٍ the Quran says that day is so serious and severe that even a woman who's breastfeeding her child and you know that's like the closest state a woman is a mother is to her child the Quran says a woman who's in that state she'll forget about her child she won't even know what she's doing وَتَضَعُ كُلْ لُذَاتِ حَمْلٍ حَمْلَهَا and a pregnant woman will miscarry وَتَرَى النَّاسَ سُكَارًا and you see that people they're like drunk but the Quran says وَمَا هُمْ بِسُكَارًا no they're not drunk but that day is a severe day so on that severe day the believer sees this beautiful image guiding him showing him how to make it to the bridge of saraat and then holding him firm on that bridge and walks him to paradise that beautiful figure takes you to the entrance of paradise and tells you here enter I've done my job you look at that figure and you tell that figure who are you you've been so good to me you saved me from all these risks who are you introduce yourself to me what will that beautiful figure say I am the Quran I am the book of God that you implemented in your life you were good to me in your life now I'd like to pay you back and God has commanded me to save you the Quran will save us on the day of judgment so my dear brothers and sisters Allah's rahmah is primarily to be seen on the day of judgment no doubt about that but the day of judgment as the Quran calls it is the day of hasra the day of regret even the good doers the believers they'll say why did I not do more why did I waste time on earth busy with other things that didn't matter so the Imam alayhi salam in this beautiful sermon and I urge all of you to study najjul balagh it's a beautiful book that really sometimes recalibrates how we view life how we live in this life the words of the imams the words of the Quran they actually illuminate our hearts they keep us firm and prepared for the day of judgment so Allah is merciful but my dear brothers and sisters there's a race there's a grand marathon tomorrow on the day of judgment let's be prepared for that race shallah all of you will be winners in that race the best of the best on the top charts inshallah right the top charts of this dunya mean nothing believe me the top charts here have nothing to do with success on the day of judgment in fact sometimes top charts here are a liability on the day of judgment because they distracted so many people not all top charts some of them maybe they were a distraction maybe they encouraged people to immorality top charts here become liability but it's the good deeds that will give us success on the day of judgment


In today's Cobb Highlight, we show you how to lose weight and gain some style at the same time with the full titanium version of the Cobb Mark 7 GTI Cat-Back Exhaust. Everyone loves modifying their exhausts because a nice quality Cat-Back can improve everything we love about tuning cars, looks, sound, and performance. Our excellent stainless steel Cat-Back provides all of that, but this titanium version takes all of those benefits even further. The tubing before and after the muffler are full three inch sections that split into twin two and a half inch sections leading to the dual exits, with matching blue burnt tips featuring the Cobb logo etched on top. The entire exhaust has a modern looking matte finish that is perfectly accented by the expertly welded pike cut bends throughout, plus a cool looking and functional brace at the Y section. Those features common to titanium parts serve as a nice reminder of the biggest advantage in a full titanium exhaust, weight savings. This entire Cat-Back weighs in at a total of only 20 pounds, which is less than half of the factory exhaust. And of course, the sound is the make or break deal for many people. Under low, this exhaust has plenty of growl without droning on the highway. Sound is subjective, but we think it has just the right increase in volume and aggression versus the steel version without going too far with either. The combo of sleek, simple style, top shelf engineering and excellent build quality make the Cobb Titanium Cat-Back exhaust for the Mark 7 GTI the premier aftermarket exhaust option on the market.


What's up everybody, JC over at Jasper's Case Breaks.com. We're doing a quick team random or 150 dollars in break credit. This sells out Pikachu number one, two, and three of Bowman Sapphire five box breaks. I can guarantee the team or 150 dollars in break credit, so the way this works, teams one and the team random will count as teams in the main break giveaway. As long as you have two plus teams in the same main break for Sapphire, and then of course we will take all 20 customer names, randomize them only, then place them up and match them up with the list below. What every team match up with is what you get, so number one is going to get 150 dollars in break credit. Number two is the Oros Pikachu number one, all the way down to Cardinals Pikachu number three. And we'll be bringing these back to back to back. So good luck guys, there's the list. Again here are the customer names. Dice Roller, let's roll it. And we got a three and a five, two five times. Good luck. One, two, three, four, and five. And boom, after five times, Daniel, odds game, got half of them, there you go, all the way down to Oliver. So, Daniel, you have 150 dollars in break credit coming your way. You also have the Oilers, I mean Oilers, Orioles, Matthew, you have the Tigers. Daniel with the Brewers, SKS with the Orioles and number two, Ryan, you have the Tigers in two. Daniel with the Astros and Angels in two, Scott with the Marlins in two, TJ with the Brewers in two, Matthew with the Phillies in two, Daniel with the Orioles in three, Rockies three, Tigers three, Daniel with Astros three, Daniel with Marlins three, Matthew with Brewers, Daniel with Twins, SKS with Phillies, and Oliver with the Cardinals. So, there you go, the way it came out here, as you can see. And again, coming up next now, guys, the Sapphires one, two, and three. Appreciate it, guys.


My name is Alyssa Carson. I am currently a 20-year-old college student studying astrobiology. I was kind of always interested in space ever since I was a little girl, and I was also interested in being an astronaut because I thought, why not go to space? Right now I'm leaning towards my grow bacteria in space, so looking for signs of bacterial life on Mars, testing those soil samples, and then eventually, let's say we do find something, running tests to actually classify that bacteria. I mean, if I was selected as an astronaut, I'd be able to do some of that in space would be the ultimate goal. We are starting to see more female astronauts, and I think that's really, really amazing because growing up I was in the environment where there were a good bit of females, but then I realized, oh, this isn't how it usually is. I couldn't find another girl with my major. I was, like, going around campus asking. I now met a couple, so, you know, we're growing. I like to think that everything in space always does come back to Earth. So for example, if we are trying to figure out this crazy thing like turning Mars into a second Earth, you know, one of the biggest things we're going to have to do that is we're going to have to clean up Mars' atmosphere. It's mostly carbon dioxide, so if we figure that out for Mars, we could definitely also clean up Earth's atmosphere at the same time. Although it does seem like a far disconnect, I do think that a lot of the things that we do in space always come back in some way for us to continue using those technologies. You know, it takes tens of thousands of people to send one astronaut into space. It definitely isn't a small task, and there's a lot of different positions that are super important. And so I think the next step really is getting more women across all of those jobs. There's no one way to be an astronaut. There's no one thing you have to study or you have to do. We want more people. We want more people to grow up and pursue STEM, so we'd probably be more than willing to help you and help support you in some way. And really just don't be afraid to talk about your dreams and just follow them.


this points to a whole new persona developer. You got eSports on the Twitch side, booming. eSports is changing the game in the whole digital sports category. Robotics, space, you got a satellite announcement. This is a genre change in digital culture. All those areas that we're continuing to expand into are areas that our customers are asking us to help them with and where there are huge opportunities for customers, but where it's hard. I mean, if you look at space as an example, if you have to interact with a satellite, it's expensive to have to have all those satellites set up and those ground antennas set up and then you have to program them and then you actually have to pay this fixed price instead of on demand. Customers say, why can't you give us access to those satellites the way we consume AWS? And then if you can have the ground antennas where when the data comes down from the satellite, it's basically on the same premises as your AWS region so we can store the data and process the data, analyze it and take action, that is very compelling. So that just felt like a natural fit. And the same thing with robotics. I think that robotics is one of the most underrated areas in technology. I think robots will do all kinds of things for us at work and in the home. People are gravitating towards robotics. Robotics clubs are booming. That maker culture goes to a whole another level with robotics. Congratulations. It's funny, we had the youngest person to ever pass the AWS certification exam is a kid named Karthik. Nine years old, he was here this week actually and I got a chance to meet with him today and I said, well after the certification, what are you doing? He said, well, I'm building a robot. And I'm building a robot. And he said, now with your launch of DeepRacer, I want to try and find a way to have the DeepRacer car be the eyes and the camera and the reinforcement learning for my robot. Nine years old.


Welcome to It's About Time on ThinkTech from our downtown studio at the core of downtown Honolulu. I'm your host Becky Sampson. I'm a professional motivational speaker, trainer, and coach. Most of us struggle with some sort of health issue. Oftentimes feeling like there are limited solutions out there to overcome these challenges. Being bombarded with endless opinions and options, it can definitely get very confusing. So today joining me in the studio is Karina Pearl and Tammy Wadsworth with PIPCO, the Pain Injury Brain Centers of America. A not-so-new technology and mostly unknown powerful solutions to everyday medical conditions. So welcome you guys. Thank you. Yeah, thanks for coming. I know it's been kind of a crazy day for all of us. So tell everybody kind of, now you're you're on island just for a short period of time, Tammy. We are. And you've been doing some training with with Karina. Kind of explain what, you're doing a franchise owner of PIPCO, PIPCOA. And thank you. I've founded PIPCOA and Karina is our franchise owner. Awesome, awesome. So tell us a little bit about what this organization is and what it's all about. Well, I will have a nursing background, a health care background. And 11 years ago I was dismayed to find out there was a technology available to professional athletes and not widely available to the general public. And I'm a pretty tenderhearted person until I find something out like that.  Yeah. And so the last 11 years, we've spent our time trying to bring this technology to the public. A few years ago we franchise and we're so excited to bring this technology now to Hawaii. I know. And it's something, now a lot of people, what is the technology? Let's start off with that, actually. And then we'll kind of go into some of the issues that you've seen or you guys have both seen because you've both been able to help a lot of people and how we can kind of do those, you know, give them some solutions for that. But what is the technology? The therapy is called AI myonervascular therapy. And basically what it is doing, it's looking for electrical disruption in the body. We're electrical beings. We produce electricity in the brain that runs the body. How many people really know that, though? Well, not too many. And so we have a lot of education to do. So say that again, we're electrical beings, right? And we produce 85% of our electricity in our brain and 15% in our heart. And if we don't produce enough electricity in the brain to run the body, then the body suffers from electrical disruption. Disease processes start. And the generation takes place. Very, very simple. I was just telling you today, I have a lot of electricity going through me today. And sometimes that causes diseases, right? Exactly. Yeah. So what tell a little bit more about the actual technology and because I know it's a machine, right? Yes. Yeah, talk about that a little bit.  This is something they developed at the end of their career. They had spent millions of dollars bringing those other devices to the public. This is something that was developed at the end of their career. A few of the scientists had retired and they just never put the money into pushing this forward like it needed to. And I really believe it's one of their greatest devices. The other devices they invented diagnosed. And they said, you know, we can see electrical disruption in the body, we can record electrical disruption in the in the brain, the heart, the muscles in the nerves. And they said, we should be able to fix it. But they didn't know how. At that time, the United States government was working on the Star Wars project. And it wasn't a movie. Although Star Wars did come out then in the 1970s. But they went to work for the Department of Defense, and they learned about artificial intelligence. And the government was that that time researching how to manipulate electrical currents, even between a millionth and a trillionth of an ampere. They learned what they could for from the Department of Defense, went back and put artificial intelligence in the devices that they originally developed. And so the devices were born in the late 1970s. But they chose to ever fully market it among the professional athletic world. Wow. So it really was just in the athletics. And now your mission really is to get it to the average everyday person. Right. Because there's so many solutions to that. Right. What Karina, tell everybody kind of how you got involved in this because this this has really made a huge difference for you.  Truly. Yeah, I'm privileged to be part of the mission of PIPCOA. Yeah. And I started as a patient, a student at BYU here in Hawaii, and Brigham Young University, and struggling, struggling with depression and anxiety that I had for many years. A lot of people have nowadays. And you know, and for a long time, I didn't know how to talk about it. It felt so different and captive inside of myself. And I did the best that I could with the resources that I had. So when I heard of PIPCOA through a family member back home in Utah, I took a break from school, and I went to go get treatment. And that's really that really was a beginning. Within a few weeks, I was sleeping through the night. I was so anxious that I couldn't go to sleep without turning. When I would turn on the lights, there was a knife under my pillow or a bat by my bed, and always nervous and hesitant. Danger. Had a little bit of PTSD from past experiences. But I kind of always put it under the rug. And it got to the point where it was getting in the way of what I wanted to create in my life. And so that kind of exhaustion where you're so tired, even blinking your eyes is tired. And so when I went through the treatments, it was a matter of days. When I started to know that heaviness in your eye, when you're so tired, it's like something's like sitting Yeah, like you're drunk. Yeah, you're heavy. Yeah, you're heavy. Yeah. And I felt light. And I felt a genuine desire to connect with the people around me, which before it really drained me. Yeah, because depression and anxiety, I know that's a lot. It disconnects people from the world. Really. And then they feel like they're like alone and feel like they're the only people that are struggling like that. And so who introduced you to this technology? So I have an aunt who lived in Utah in the same neighborhood as the owner of the franchise, Utah and St. George. And she's like an auntie and her niece was going through treatment. So seven year old going through treatments. It's a little didn't really understand what PIPCO was when I was told over the phone. But I heard that there was pretty incredible results in the behavior of my love little girl, you know, and so it took a risk and went on the leap of faith. And it was one of the greatest decisions I've ever made in my life. Was it something that you were familiar with with this technology? Or I mean, was this all totally new to you? Absolutely not. Totally new that our bodies are electrical beings.  And but that's as much it that I understood really how the body also had a physical side of physicists, not just the chemical side. And that if we looked at the body through both ends, that the physicists really could lead the chemical beautifully. And I saw that in myself. At the very end of treatments, I knew I I don't have that feeling where you come across something you were prepared for. Right. And it's easy. It's natural. And you feel it so deep inside. And that's really what led my government choices after that, when it came to wanting to know everything about what was the mission behind. And that's when I discovered it was a franchise. Well, I think you've got a great point because a lot of times we were actually on the way here, we were talking a little bit about how sometimes people can feel kind of Lulu about anything that's electrical or quantum physics or any of those kind of things. What have you been doing? You don't really need to know everything about the science of it to know that it still works. It works, right? I mean, have you found that? Or did some people may come into treatments that know about it? And some don't. I mean, you didn't know a lot about it. So this is totally new to you. You just knew it worked. Right. The great thing is, you know, some people ask if what we do is alternative medicine. Because they think it might be on the fringes and be out there. Yeah. And I say, absolutely, if you're thinking non drug, non invasive, however, I live 40 minutes from Rochester, Minnesota, and we call her mother male, the Mayo Clinic. And so I know many doctors through the Mayo Clinic. And what's important to know about this technology, they're class two medical devices. So we have the science and the research to back up our claims and to validate what it is we do. We are electrical beings, that if you don't heal from an injury, it's electrical disruption. If you have an injury, it's electrical disruption. If you have something of neurological going on, it's electrical disruption, people say, Well, it's chemical disruption. And I say, Well, what caused the chemical disruption? It was electrical disruption that caused the chemical disruption. So when we treat things like addiction, depression, bipolar, but also any type of traumatic brain injury, concussion, anything going on in the body, equipment is looking for it. They're class two medical devices, we have the science to back up our claims. We have the research. And it increases the body's own ability to heal by 500%. The documented 95%. I know, and that's a pretty amazing statistic to be able to say that 95% of the people that come into your clinics, with all kinds of issues that you can you can help them improve those things through just the electrical current, right that you're that you're is it rewiring? Is that what it is? Maybe reconnecting reconnecting reconnecting reconnecting. Yeah, I know when you did the treatment with it with us last week, you know, it was you can you can tangibly feel it. At least I did. You can feel the energy going through and being able to feel a lot more grounded. And even though you don't understand, I know oftentimes as a public speaker, we talk about, you know, all of us use electricity, but we don't know how the electricity really works. You know, we just flip the switch and it works. Right? So when you have people come in and it's what a great story that I mean, you didn't know much about it. And then you ended up getting the results and you're like, Hey, other people need this. Right? That's such a great purpose for you to want to go out and help other people. I think that's opportunity you you can create when your body works with you. And together and you discover it's an instrument. And that it wants to heal. And when you incorporate everything together, it works as a whole. And we just get to do the electrical side. And something that really helped me was, you know, when you go to the doctor, you have a heart problem.  That electrical current that brings you back. Yeah. And something that's really important to understand is that AI, it's just a simple way of saying it's like eekiness, you know, it's a calculator calculating math really fast. What's a calculating your information of your tissue? And then the electrical current, it's microcurrent. So gentle. It is impossible for us to hurt you through what energy frequencies deltas, betas, betas, alphas, gammas, and they work together to create the optimum results for a person. Yeah. What would you say the most common issue that people have when they come into the clinic? Neurological. Neurological. In what sense? Like what are some of the conditions? Neuropathy, pancerphysiitis, neuropathy from diabetes, ALS, Parkinson's, degenerative diseases, neurological conditions. Ideal partnership would be with a neurologist. Because 98% of my patients have a neurologist. And they're at a standstill. They have the best support that there's something, something or somebody missing on their team. And when they come in, I see people from their wheelchair go into their walker within a month. And how many treatment treatments are there during the week? Or is it once a week? Or is it? That's a great question. So we're working with cells and increasing their capacity to hold electricity. So stem cell and the family of cells, just noninvasively. And so it takes time for us to send signal, get the detox out of the body. And the cells begin to get stronger, maximize, energize, hold, so that it's at its full ATP level. And so the minimum is at least four times a week for patients to come.  You have things waiting for you and you can maximize, you know, two to three times a day or six times a week, at least the minimum and still having the great quality treatment results, or minimum. Awesome. Give people an example of what a treatment is like. They probably don't, I mean, they probably think you're going to zap them or something with these electrodes, but explain to them because it's really gentle. It's so, it's super gentle. But explain to them kind of what you do when they come into the office for the first time. What can they expect? So everything is non-invasive pain-free. So imagine going to your typical visit. You're in a waiting room, music playing, anticipating waiting, and the clinician will greet you. The clinicians are trained to be able to work and be the facilitators. And they're sweet. They're very nice. And most of the time they're CNAs, or they're massage therapists. So they're acquainted with the body and they love working with patients.  And we'll show you, depending on the treatment of that day, we have quite a few tools for different symptoms. Very wide range. Typically. So yes, we're gonna go to a break real quick. And I want you to finish telling people kind of what it's like when they come into the clinic. Because I don't want them to be scared at all. Because this is, this is actually a really great, a great service that you provide for sure. So we're going to be taking a short break. I'm Becky Sampson. This is on It's About Time on ThinkTech. We're talking to Karina Pearl and Tammy Wattsworth with PIPCO, The Pain Injury, and Brain Centers of America. We'll be right back in just a minute. Aloha, my name is Victoria and I'm a host at The Adventures in Small Business. This is a collaboration between US Small Business Administration, Hawaii District Office, and its partners, where we showcase the stories of local entrepreneurs in small businesses, talk about how to start a business, talk about great tips for small business owners. Please join us every Thursday, 11 a.m. at ThinkTech, Hawaii. Can you say mahalo? Hello, I'm Mufi Hanomet. I want to tell you about a great show that appears on ThinkTech, Hawaii. It's all about tourism. In fact, we call it Tourism 101, where we talk about the issues and challenges that face our number one industry throughout the state. We'll have some interesting guests, very informative dialogue, and allow you an opportunity to maybe learn a little bit more about why this industry is so important for our state. It's been great for us in the past, we need it today, and especially going forward. That's Tourism 101 on ThinkTech, Hawaii. Mahalo. Hi, we're back. I'm Becky Sampson, and this is It's About Time. I'm with Karina Pearl and Tammy Watsworth with Pipkoa.  Absolutely, it's a question everyone has. Yes. Yeah, what is it going to be like for me? So, it's your typical experience waiting in a waiting room for a clinic to see your doctor or a visit massage therapist. You come in, you're waiting in a waiting room, a clinician who facilitates the treatments through the medical device trained and certified. You will be a massage therapist, DNA by trade. They'll come in, they'll greet you, they'll welcome into your room. Now, everything's going to happen in an atmosphere with a massage bed. You'll see the medical device. Number one is you'll get introduced to the medical device. You'll get a preview of what we're going to do that day. The most important thing that really sets us apart is the connection we get to have with the equipment. And so the equipment really, in this part, in this piece, you'll really understand how much we are the facilitators of the equipment and it's not based on our knowledge, obviously the protocols, but the AI will take readings of the body. So everything will... So they'll do a diagnosis, basically. So it's not that somebody can come in and say, hey, this is what's my problem. No, let's really find out through the body what the body is giving us feedback of what the real issue is. If I might interrupt. The devices don't diagnose, but they're telling us exactly electrically where the problem is and where the disruption is. Okay. So then you know how to, where to go in the body to reconnect. Right. Okay. Mm-hmm. So you're hearing for a disconnection, which is zero numbers, or low sound, like static. They'll be hearing that sound or really high tones, or high inflammation. We'll take care of that first. So a lot of times people will come with a migraine or they'll come with neuropathy and they can't feel the toes or they feel needle pain in their toes. The disconnection is going up in their brain, down the spine, and not signaling fully and correctly to the feet. And so we're going to follow up that line, the meridians, acupuncture points. Once we are clear on that, and we work with that first, then we facilitate the protocol. And I see it as there's no more resistance so then the body's open to receive. So how important is it, now this is an interesting concept, but how important is it that the person being treated believes in the treatment? I'm going to ask Tammy that because we have a personal experience, right? We do. How important is it that you at least be open to the possibility of this technology being able to to reconnect those connections? Well, we tell people, the joke is probably people don't get better as fast as the happy people. So our goal is to make every patient laugh or smile. And people say, well, I'm really skeptical. I say call my bluff because it'll work whether or not. If some people really have some problems going on and some real electrical disruption, it might be important to treat the brain first to clear that blockage so that they're open to receiving. And would that be a case too for PTSD? Because you and I have talked about that and how powerful this technology is for people that struggle with PTSD. It is. Because I think that's probably a scary thing for people that have had PTSD to go back and relive all of that where this really goes to the core, right, and helps to repair that damage that's done in the brain. I think when we treat things like obviously we do regular hips, backs, knees, the traditional things when you think of pain or injury, but when we talk about the neurological, when we talk about depression, when we talk about PTSD, when we're talking about bipolar, and we take readings of the brain and can see where the disruption is, people look at us with tears in their eyes and they say, you mean there really is something wrong with me, that it's not just emotional. Yeah, they're not growing crazy. Yeah, that it's something that we can see the electrical disruption and then the equipment with the artificial intelligence sends out a corrective signal and really that's what makes the devices different from other electrical devices out there is the artificial intelligence and the equipment's ability to read the tissue and then through the artificial intelligence send out a corrective signal and then it recalibrates a hundred times per second. Well, I know when you did mine a week ago or so you said that, what was it my brain was? Your readings were low. And so what does that mean? Is a normal healthy tissue resonates at a certain frequency. Anything that's impaired, injured, diseased, or degenerated registers at a lower frequency. But most of our disease processes start with inflammation, so then your readings are too high. We need to increase your pigments in your fruits and vegetables. I eat so well. I can do. And so it might be increasing your good oils to facilitate the absorption of those pigments. But that's also, I mean, that's bringing something to an awareness. Again, I always say, you can't change what you don't know, but you don't acknowledge and obviously having a machine to be able to look. I mean, how do we know what the electrical currents are doing in our bodies and how they're affecting our every day and how many people beat themselves up over depression and anxiety when really, it's just misconnected. I don't know what the terminology is, but.   Yeah, that's true. I know you've got some slides, too, that you can kind of go over. Yeah. I don't know which would you like to address first? Well, if we go on to the next slide, please. It's a proper implementation of the protocols. We are able to increase the body's own ability to heal by a documented 500 percent success, 500 percent. It's non-drug, it's non-invasive. The results are quick. Most of our patients start to feel the results in the very first treatment. And they're surprised. They get off the table with tears in their eyes and they say, I can't believe that I feel better. I put my hands on my hips and I say, isn't that why you came? But people are so used trying things. Yeah, and not having your work. And not having the results that they go for. And especially with drugs. Right. You know, we talked about that on the way here as well is that people are over drugged where it's, if we can look at alternative things whether it's nutrition or whether through this kind of technology to be able to help them that's non-invasive, you know, to really get to the core because there's too many things that are, in my opinion, we could get really a political about this, but in my opinion, we're just dealing drugs out so much when there's other things that are out there. So I love that this is a different way of attacking at the core, at the core. Yeah? Yes, absolutely. And so, and what's important to know is this technology spent around a long time about that same scientific team that gave us some of the greatest diagnostic equipment available. And this was one of the, one of their last devices that they brought to us. And why do you think it hasn't gotten out to the Republic? Just they didn't, they didn't get it out there? I think that maybe the medical industry today doesn't see that there's enough money to be made in it because when you're thinking, you know, for a simple carpal tunnel we treat someone Monday through Friday for two weeks, it's about $1,500. But that carpal tunnel surgery is typically $25,000 to $30,000 employs a lot of people. For us, we're happy to bring this technology and we're happy, you know, to do that. We're not looking for the $25,000, $30,000. So. And do you work with insurances as well? Like I know you had mentioned, you can go through the alternative, is that right? Well, you can't, we can give patients a super bill. We don't choose to bill insurance because we can give our patients a better price if we don't bill insurance. Right. And so. But a lot of health plans could probably use, I know when I did my health plan, we just went to alternative stuff and then just gave it back to our what do they call it health savings plan? And we can run health savings account. Cards like a credit card. We can do that. There are alternatives. There are financing options. And so when people say we'll do bill insurance, we ask them, have you met your deductible yet? And try and set them up to meet that deductible and then take it from there. So it's an engages in a conversation because the purpose of PIPCOA is to bring this to the public. Yeah. It's a crime that this hasn't been available to the general public. You know, I became a nurse in 1982. That's not just yesterday. I'll bet that was before you were born. She's so cute. And but the thousands of people that I have seen suffer over the years that didn't need to die or didn't need to suffer their whole life. They would have had access to this. Yeah. So that really is the mission of PIPCOA is to go out and find them. And the franchise model was the best way for us to go out and find them. Which your opening franchise is all over the place. We are. I mean, I know you're only here for a couple weeks. Right. But then you're off to other places opening up and doing trainings and helping people really learn. You've been here for a week. Right. Week and a half. Week and a half. Yes. Training. Awesome. So what are the what are the things can people if they're if they're listening right now or if they know people that are struggling how do they get a hold of how old of you or here in Hawaii or if there's nationwide? That's a great question. We were in Las Vegas when we started and we got an important phone call and connection to a patient in Queens hospital. And thankfully through a lot of the support there we were able to treat man from the big island who was paralyzed with a neurological condition. And my husband is from here from Kuhuku and it was our dream to come back here and to offer this gift. And so at our clinic we have packages. We fluctuated prices to be able to feed fit the needs excuse me fit the needs of local families. And it's been a pleasure to increase our staff. Local beautiful women that have a desire to increase their knowledge and give back to their community. And that's our number one. And so we have a location in Kaniohe. We started in Kuhuku at a wellness center Kola Wellness Center. And I've been to your place. Yeah. Yeah, Kaniohe. Yes, we just had a warm ground opening just a week ago. And we are ready our biggest desire to move so quickly was so that we could have wheelchair accessibility. We have a wheelchair accessible room that was the most filled room we have. And with multiple treatment rooms so that we can help variety of people that are seeking answers and direction that know that there's something missing and hoping that this may be the last stop. That's awesome. That's awesome. And give me your phone number of where they can call you. 808-2-0-3-9-3-6-5. Awesome. And thank you so much Karina and Tammy for being on the show today and sharing this technology with the people in the community and whether they're here in Hawaii I mean this goes on internet so or they're all around the world. Is there a website a main website that you have? The website is www.tibcoa.com And Becky I want to say from my heart thank you so much for having us because you are going to be the instrument in helping so many people with your heart and your desire to get this out so we want to thank you. Thank you and thank you for treating me. You're welcome. Telling me my brain needs some more stuff going on right? So thank you guys so much for coming on. We're out of time today and we'll wrap it up so I'm Becky Samson with It's About Time on Think Tech Live streaming network series. We've been talking to Karina Pearl and Tammy Wadsworth with PIPCO, The Pain, Injury and Brain Centers of America. So thank you to our broadcast engineers or and our floor manager and to Jay Fidel our executive producer who puts this all together. So and of course I'll see you next Wednesday for more of It's About Time on Think Tech. I'm Becky Samson. Aloha everyone.