Welcome everyone, this is Dr. Steven Gundry and I'm talking today with a colleague of mine who I've gotten to know over the past year. We've actually known each other's work for many years and I'm a huge fan of this man and what you're going to hear today about his new book, The End of Alzheimer's, I think is going to be really revolutionary. And I'm just delighted to have you, Dr. Dale Branson, today talking with me. Thanks very much, Steven. I'm a huge fan of your work and you as well. In fact, I'm actually starting phase one of your protocol right now myself, which I think is fantastic. It actually fits very much with what we found in the test tube over the last 28 years on Alzheimer's disease. Yeah, I think that's very true and so what I want to do today, Dale, is get a feeling of, you know, what, first of all, what compelled you to write this book, The End of Alzheimer's? We have been looking for the last 28 years in the laboratory, basic neuroscience at what are the actual driving factors? Why do people get Alzheimer's? Why is it so common? As you know, it's now the third leading cause of death in the United States and by the way, number one in the UK. So this is a major and growing problem and as you know, complete failure on the therapeutic side. So we wanted to understand the basic mechanisms of this disease in enough detail that we could ultimately do something about it. And over the years, what we found is that this is very different than something where there's just one cause and it's one disease and it's the same thing each time. It's not like pneumococcal pneumonia. You don't take penicillin and it goes away. This is, if you could imagine looking at a car to say, why is the car not moving? Imagine that you found 100 things.  So what we found is that there are many different mechanisms and they all interestingly come together on a balance. So just as you get osteoporosis, when your osteoblastic activity is chronically exceeded by your osteoclastic activity, so it turns out you get Alzheimer's disease when you're synaptoblastic signaling and there are dozens of these signals are exceeded chronically by your synaptoclastic signals. And you can actually see this at the molecular level and you can actually see it at the human level. You change that balance, people start to get better. And many of the things that you've talked about in your book, especially some of the immune related things, leaky gut, chronic inflammation, all of these fit in. So we realize we now have actually over a thousand people who are following this protocol started back in 2012 after the research guided us here. We said, well, wait a minute, this should actually help human beings. Of course, I actually thought I would die still studying mice and cells, but we started to see humans getting better and we've now seen this in hundreds of people. So very excited. So I wrote the book actually so that people would understand that this disease is different than what we've actually been told. It's a very different disease. And in fact, there's a lot you can do about it. The reality is Alzheimer's should be a rare disease. Yeah, I think that's an amazing point. This disease didn't exist really. When when you and I were growing up, there was the odd case that everybody knew about. But it's a brand new thing. And there are societies that you and I know about where even if you carry the quote Alzheimer's gene, the Apple E4 gene that you don't develop the symptoms of Alzheimer's disease. So can you give me maybe you can share a little of the background of your studies with maybe some of your patients that have had, you know, reversal of their Alzheimer's or cognitive decline? Yeah, thanks, Stephen. So let me start by saying that the concept of this disease that has literally come out of the test tube research is very different than what we've been told about this disease. And what we discovered is that Alzheimer's disease, the thing we call Alzheimer's is actually a protective response to three fundamentally different insults. One, we've already talked about chronic inflammation. Anything you do to give yourself chronic inflammation, whether it's Lyme disease, whether it's HSV1, whether it's leaky gut, whether it's problems with your rhinocinal microbiome, what have you? Chronic inflammation causes your brain to make a protective response. Why? Because amyloid is a wonderful antimicrobial, as Rudy Tansy and Robert Warren, their colleagues at Harvard, showed beautifully. Second thing, if you withdraw trophic support, so things like estradiol, nerve growth factor, BDNF, vitamin D, testosterone, progesterone, prognatalone, free T3, we can go right down the list. Your brain actually cannot support any longer at this massive network. You have close to a quadrillion connections in your brain. If you can't support them, your brain does the same thing your company does. It says, okay, we can't hire any new people, can't add any new memories. And so that is the canary in the mind. And that is part of a programmatic downsizing. And it is mediated by amyloid. The third thing, if you have specific toxin exposures, be they biotoxins like mold-related mycotoxins, things from Stachybotrys or Penicillium or Aspergillus, or they're chemical toxins. Mercury is a big one. Copper, too much iron, all of these things. What do you do to protect yourself? You make amyloid because it binds these toxins. In fact, it's one of the best binders known of copper, 10 to the minus 18 molar. It's incredible. So you are protecting yourself. So the last thing we want to do is get rid of the amyloid. What we want to do is get rid of the reason for the amyloid. Then get rid of the amyloid. That's fine then. So what we realize is, okay, we need to now address all these different things that we need to determine for each person. Why is this happening? So we started to do that first person back in 2012. We actually tried to do initially a clinical trial. We were turned down because the clinical trial was, quote, too complicated because we were manipulating more than one variable. We said, yeah, but this is more than a one variable disease. This is a complex chronic illness. So we've had now, as I said, hundreds and hundreds of people. I'll give you a couple of examples. One person who is now 73 had had problems, ApoE4 positive, PET scan proven, Alzheimer's, showed with quantitative neuropsych testing over the years to decline down to where his CVLT was at the third percentile. Started the program in December of 2013, came back for retest, did very much better subjectively, but came back for neuropsych retest after 22 months, did absolutely beautifully CVLT at 84th percentile. Auditory memory went from 19th to 78th percentile. So this guy is going from doing very poorly, not remembering much of anything, to actually having a better memory than most of us. So he did very, very well. And he's now three and a half years into this and a little more than three and a half years and has actually done exceedingly well. He was actually shutting down all of his offices. He's opened new offices doing great. Another person who has done very well and had a low mocha score of 24, which means pre Alzheimer's, now has a mocha score of 30, which is perfect. Had amyloid PET scan proven Alzheimer's and actually got worse on a drug trial and has actually done exceedingly well. Again, with addressing all of the different things. And just as you talk about in your book, you have to address the root cause of the problem. To try to trick nature with a drug that is basically trying to trick your physiology really makes no sense. That's 20th century medicine. 21st century medicine is no longer about the what, it's about the why. Why did you get it? What are all the contributors? How are they acting? Is leaky gut among your problems? And then in microbiome changes, whatever they are, they need to be identified and addressed. And we see again, repeatedly improvement after improvement. Yeah, I mean, it's fantastic.  You suggested that I start measuring pregnant alone in my patients. And quite frankly, unless it came from you, I would be skeptical. Pregnant alone is not usually measured in a standard endocrine test because you need a mass spec machine to run it. But I started measuring right after we talked a year ago, pregnant alone. And you told me that 95% of adults I would find deficient in pregnant alone. And I can tell you that you are absolutely spot on. About 95% of my adult patients are basically completely deficient in pregnant alone. And as you taught me, pregnant alone is an incredible neuro-stimulating hormone.  And unless you had done this fundamental research, practicing physicians like myself wouldn't be knowledgeable of that. And I personally thank you. And my patients, thank you for that. It's an amazing observation. And you're right.  And we've been very naive to think that we could knock off amyloid plaque and solve the problem. And really, thanks to your research, we're beginning to figure that out. So you brought up all these different factors. There are these different types of Alzheimer's or cognitive decline. And can you kind of talk about those three that you've defined and then maybe tell us how a functional medicine approach or what I call restorative medicine approach makes this possible? Yeah, a very good point. So when we started the research, of course, I knew nothing about functional medicine. My wife had told me 25 years ago, and she's an integrative physician. She had told me 25 years ago, you know, whatever you find in the test tube over the years, all these years of research, you're going to have something to do with things like nutrition and exercise and stress and sleep and all these basic things. And I laughed at the time and said, no, no, no, we're going to find, you know, one molecule, one domain. We're going to get a drug that's going to interact with one domain of one tiny molecule and everything's going to go away. And of course, the research showed just the opposite. That it showed that there's this beautiful network.  And what we realized, we now in the 21st century must think about Occam's network. What is the network that is contributing to your disease and about silver buckshot, not a silver bullet? Yes, you want to target all these critical things. That's great, but it's not just one thing. That was pneumococcal pneumonia. That's not the way these chronic complex illnesses work today. So we need to measure all these things. We need to look at them. We need to look at why they have changed. What is actually going on? When we started to do that, we now look at 150 different things. And by the way, this is of course what the cancer research centers are doing. They're looking at the whole genome of the tumor, the whole genome of the host. Of course, we want to go beyond the genome. We want to look at the metabolome and the lipidome and all this sort of thing. But we look at all the things that are actually driving the cognitive change or risk of cognitive change. And the first thing we found was that there are these multiple subtypes, as you mentioned. So these go very much with the idea of what amyloid is actually doing to help you. So number one, we find people who have cognitive decline. And this is when I say cognitive decline, these are Alzheimer's patients. So they have amyloid and they're making it because of chronic inflammation. And as you know, many causes. These are people with gut leak. These are people with Lyme disease. These are people with eating trans fats. These are people with high hemoglobin A1Cs, with all sorts of advanced glycation end products. Autoimmunity, all the things that you've talked about. This does contribute to what we call Alzheimer's disease. And in those cases, we need to identify why that is, and then we need to reduce it. So we use, for example, the specialized pro-resolving mediators. We use the appropriate omega-3s. When we need them, we use everything possible. And the critical thing, again, is to identify the source. Then we see people with metabolic syndrome, what we call type 1.5, which is glycotoxic. These are people who have this combination of the inflammation from the sugar, but also the trophic loss from the insulin resistance. So their neurons are no longer sensitive. And in fact, a beautiful work by professor Ed Getzel out of UCSF, who showed that virtually 100% of people with Alzheimer's disease, if you look at their neural exosomes, so you're actually looking at fragments of brain cells that are in the blood, he could show that they all had insulin resistance. They've literally changed their IRS-1 signaling molecule through phosphorylation events to reduce its sensitivity to insulin. So you are insulin resistant at that point in your brain, whether or not you are peripherally. Very scary. Then, second one, of course, we see many people where that's not the problem. They don't have a lot of inflammation. They don't have a lot of sugar-related problems. But what they have is no longer the support. Their estradiol is low. Pregnenolone, as you said earlier, they may have Pregnenolone steel, as you know, where you're basically taking that Pregnenolone and you're moving it into cortisol instead of to estradiol or testosterone or progesterone or things like that. So they do not have the support. Their brain-derived neurotrophic factor may be too low. Their NGF nerve growth factor may be too low. Their vitamin D may be too low. And we see these people. And they tend to present differently. So the typical person with the atrophic, this type 2, is in their 70s. The typical person who has a type 1 is in their 60s.  And again, you mentioned diseases we didn't see as medical students. And I've actually talked to a few of my neurology colleagues recently saying, have you ever seen this disease before, this type 3 Alzheimer's? Nobody has seen it. It is a hidden epidemic hidden underneath the umbrella of Alzheimer's disease. But when you and I were training, when did we see a 52-year-old woman with severe Alzheimer's disease? It just didn't happen unless they had familial mutations, which these people do not. So this is a toxin-related Alzheimer's. And by the way, if you have any doubt about toxin-related Alzheimer's, take a look at the World Trade Center first responders. 12.8% of them now have cognitive decline in their 50s. This is very concerning. And some beautiful work done out of New York looking at the follow-up. So there is this toxin, which is the type 3 related. It looks different. It's typically non-amnestic. These are people who have trouble organizing, trouble planning, trouble calculating, trouble word finding, trouble with visual perception. This is very different than type 1 and type 2 Alzheimer's. Yeah, you know, Michael Greger, the author of How Not to Die, who is a vegan physician who I respect a great deal, likes to point out that executives in the Miami, Florida area, where they consume a lot of fish, actually have marked cognitive decline because of the mercury levels in the grouper that's very popular in southern Florida to eat. And he makes a case of not eating fish because of that. But the more important case, which you would make, is, well, it's the mercury toxicity of in those particular fish that was actually part of their cognitive decline. And as you well know, you want to have smashed fish. So, you know, salmon and mackerel, anchovies, sardines and herring.  Absolutely. Yeah, last month I was down in a small village in southern Italy called Aciaroli, which I talk about in my book. These are actually now the greatest percentage of over 100-year-old people of any town in the world. About a third of the town is over 100 and functional. They have a diet of anchovies, rosemary, olive oil, and wine. And they have anchovies for breakfast, lunch, and dinner. And they actually have fried anchovies, but they fry them in olive oil. And I got to sample quite a bit of it. And you're right, they're eating tiny fish. And I think if we could get Dr. Greger to realize the fish is not necessarily a fish, that there may be beneficial fish for us that we'd all agree. It's the toxins that these fish acquire that are the problem. And as you've pointed out, you want to stay away from the farmed fish. Oh, yeah. You know, we have to understand that when we feed animals, and fish is an animal, things that they're not designed to eat, and we lace them with antibiotics, we totally change their microbiome and our personal microbiome. And we actually change really the cellular constituencies of those animals at a basic level. In fact, I was just talking with the medical director of our hospital yesterday, who was actually trained as a veterinary scientist. And he was telling me about their poultry courses. And he said, I can tell you to this day, because I'm still involved with the research, that 100% of our free-range chickens in this country are fed antibiotics. And he said, do not believe anyone who claims that they're antibiotic-free because you have 100,000 chickens in a warehouse crammed in together. And if one chicken gets an illness, you are not going to single out that one chicken. You are going to pan-treat them with antibiotics. And he said, it is one of the great lies that's been told to us that these chickens are antibiotic-free because the FDA, even though condemning antibiotics in chickens, allows the veterinarian on site to make a decision to give antibiotics to save the flock. And guess what? They always make that decision. And the thing is that we have found that there were a lot of assumptions made in the last 100 years with increased industrialization and food, for example. And of course, in the pharmaceutical industry, lots of assumptions made that have simply turned out to be incorrect. You can feed these animals anything, all sorts of things. You can put them together as closely as you want. These are just incorrect assumptions, and we're now paying the price with our health. Yeah, absolutely. You and I both think that a great deal of this at the cellular level has to do with mitochondrial function. And can you kind of tell our listeners today where mitochondria, the little energy organelles in the neurons fit into this grand scheme? You know, this is a great question. So for one thing, amyloid actually interacts with the mitochondria. So it actually has a direct impact on mitochondria. And again, it is part of a downsizing phenomenon, as I mentioned. It literally changes your metabolism. However, we published a paper actually a few years ago with an expert, Dr. Martin Brandt is one of the world's experts on mitochondrial physiology. And interestingly, you know, we used the mouse model and said, okay, can we detect mitochondrial abnormalities in their synaptosomes early on? So in just the area where they're actually having neural transmission. And the surprise was, we did not see any changes early on. And one of the things we realized is that mouse Alzheimer's, what we call mouse Alzheimer's, is quite different than human Alzheimer's. When we give it to the mice, what do we do? We give them a mutation that is very, very rare in humans. So it's a horrible model. In humans, you have many, many different things feeding into this. But as you know, it is very difficult in a human patient to measure and with an easy lab test, you know, you can measure things like organic acids, these tend to be abnormal very late in the process. In fact, we need better tests of early mitochondrial changes that can be applied to people early in the course and people who are at risk. I believe that the neural exosome work where we're now starting to look at these exosomes, you're literally looking at brain chemistry in a blood sample, which is very exciting. And that's the coming thing. I think that will be very helpful for pointing us in the direction of what are the actual changes, as you probably know. In fact, the data are much better for absolutely clear complex one abnormalities in the mitochondria in Parkinson's disease. What data we do have suggests that it is more complex four in Alzheimer's disease. So I have no doubt that you're right. I have no doubt that these will play an important role. But it's actually been quite difficult to tease out where it's coming from and whether, in fact, people early at risk actually have such changes. You know, you and I are both big advocates of fasting, speaking of mitochondria. Absolutely. And you know, why is fasting good for brain health? And what do you think about the optimal timing for fasting? You and I both agree on this, but I want to hear it from you. You know, this is a great point. It's so funny that, you know, when I was training, I was much younger. I would see, you know, what's, I would see what's going on with these various... Sorry. Sorry. I forget to do that all the time. I apologize for that. So in any case, you know, when we were younger, we would hear about these old civilizations, things that, you know, Ramadan, things like this. Oh, you've got to do this. This has started hundreds of years ago. And I would say, what's the point here? And in fact, obviously someone knew what they were doing. And in fact, there are a lot of advantages to fasting, as you know. And we should all be doing it. So what we recommend to the patients as part of the overall protocol that we call RECODE for reversing cognitive decline. And I go into this in the book in detail. What do you need to check? What do you need to do? And when you do this, so we recommend between 12 and 16 hours between finishing your dinner and starting your breakfast or brunch or lunch, whatever your next meal is going to be. So you need to have that fasting period. And then three hours before bed. And here's the reason that there are many reasons, as you know. For one thing, as your brain now is shutting down and as in terms of new food exposed to it, it literally changes. Number one, it will start to remove amyloid. It will start to clean out. It will induce a process called autophagy so that you're actually going to start cleaning out your brain.  And interestingly, while you're sleeping with this fast, you actually change fundamentally the micro anatomy of the brain. So you were literally flushing out the brain during that time.  Now, as you've pointed out, if you are ApoE4 positive and that includes about two-thirds of people with Alzheimer's disease and it increases your chance of Alzheimer's if you are ApoE4 positive, then in fact you should probably make that 14 to 16 hours. If you're ApoE4 negative, then you can make it 12 to 14 hours. But you want to have a significant fast to allow your brain to cleanse itself and actually to help reduce the inflammation, to help reduce the accumulation of abnormal proteins. Yeah, I think that's a really critical point.   And we actually shunt a huge amount of blood flow to our gut in digestion. And what your work and others have shown is that during sleep we have to have increased blood flow to our brain to do this deep cleaning that you and others have discovered. And I think what people have to take away is we don't tell you, well, fast three hours before you go to bed, it's actually because you don't want blood flow going down to your gut and stealing what would naturally be happening in your brain. And so if we put this in practical terms that people can, you know, can understand, okay, I don't want to get a cramp in my brain, I need big time blood flow at night when my brain is cleaning itself. And, you know, we're beginning to discover, you're right, that so much of the brain can be cleaned as long as we have the opportunity for the brain to clean itself. So your message is well taken here. It's amazing how important the combination of optimal nutrition, exercise, sleep, and stress reduction, and then of course that relates to microbiome as well. It's remarkable how powerful these are and how often they are forgotten by many physicians. So what are the other practical things that you talk about in your book, The End of Alzheimer's, that people can do in their everyday lives? Well, again, the thing we recommend first and foremost is to get a cognoscopy.  So you should know these things because they are important to you. These aren't, you know, strange things that you don't need to know. This is determining your future. Are you at risk for Alzheimer's? And then, when you know what your risk factors are, you want to optimize each thing. So we tell the patients, you know, imagine you've got a roof with 36 holes in it, you know, you can look at those holes with your cognoscopy and then you can plug the appropriate ones, but you don't want to just plug one, which is what the drug does, you want to plug all of them. In fact, I believe the drugs work much better if you actually would plug the rest of the 35 holes. So to get back to what you said, yes, you want to include optimizing your microbiome. You want probiotics. You want to heal your gut if it is leaky. And as you point out, many people have leaky gut and are not aware of it. You want to help bring down your HSCRP. And that may take some pro-resolving mediators, but it may just take some good fish oil and some good antioxidants. You want to make sure that your vitamin D is optimal. There are so many people who are deficient in vitamin D, as you know, deficient in magnesium, deficient in iodine, deficient in zinc. These are so common in our society. You want to make sure to get off the proton pump inhibitors. You want to make sure to get on the appropriate vegetables. These are all powerful things. You want to optimize your hormones. So as we tell the patients, we're now going to treat you like a competitive athlete. It's no longer good enough to have a B12 of 350, even though that is, quote, within normal limits. It's not optimal, as you know. This is a fairy tale that the two standard deviations is the way we should be optimizing things. So we want to have your B12 level over 500.  That's absolutely critical for your cognition. If you are a female, of course, same idea with your estradiol and progesterone and, of course, pregnenolone and DHEA. These are all critical parameters. Many people, as you know, are mildly hypothyroid. We want to understand why that is. We want to make sure that your thyroid is hitting on all cylinders. That your reverse T3 is not too high. We look at the free T3 to reverse T3 level, which many people do. We want to make sure that your TSH is not too high. Many people are walking around with TSHs of 3 1⁄2 and being told those are normal, but they're not optimal once again. So these are all critical. The type of exercise you do, you want to get some cardiovascular, but you also want to get some strength training. One of the most critical things is you want to achieve insulin sensitivity. So if you're walking around with a fasting insulin of 10, although your doctor may tell you that's normal, it is not optimal. We want to see it, you know, below 5. We want to see your hemoglobin A1C, you know, 5.5 or below, preferably. We want to make sure that your fasting glucose is below 92. So we want to optimize your insulin sensitivity. And now, of course, with the neural exosomes, we'll be able to look directly and say, do you have phosphorylation of your IRS1 that is preventing signaling in your brain? So that will be a very powerful addition to this. So we want to optimize your insulin sensitivity. And of course, that's fasting as part of that, as is exercise. And so all of these things are critical. And then one of the things that's ignored by most people, and it's just shocking how many people are ending up with type 3 toxic-related Alzheimer's disease, we want to know what toxins you are carrying in your body. And you know, Dr. Joe Pizzorno made a really good point recently that as people get to 50, get to the menopausal time or andropausal, they start losing some bone. And as they release the bone, of course, mercury is coming out, which they've stored for years. That many of these toxins, not just mercury, are all sitting there. You've stored them away. You've kept them from harming you. And this, we believe, is now why so many people are turning up with type 3 cognitive decline right around the age of 50. And in fact, when we include in the treatment an optimization of their BHRT, of their hormone replacement therapy, they do much better. So this is likely to be preventing continued release of this because you need to find the source of the toxins and you need to remove it. So this is another absolutely critical thing to optimal performance. And then, of course, as we talked about earlier, what's your magnesium status? We want to know your RBC magnesium. What is your copper-to-zinc ratio? If you're walking around with a high copper-zinc ratio, that was shown 30 years ago to be associated with dementia. So all of these things are critical to evaluate and optimize. You know, speaking of TSH, I do a complete thyroid panel on all my patients. And one of the interesting things, one of the probably only smart things the government ever did in the early 1900s was to mandate iodine in salt. And we're seeing, at least in my practice, and I talked to other restorative medicine docs, this switch to sea salt or Himalayan salt, I'm seeing a kind of all of a sudden an iodine deficiency in so many people. And they're running a slightly high TSH and their docs tell them everything's fine. In fact, their docs, if they measure a thyroid function at all, it's TSH. And if they're lucky, they get a T4 and a T3, but never the free form. And I've been fascinated. All I do is either ask them to go get iodized salt again or iodized sea salt, it exists, or I just ask them to take some spirulina tablets so that they can get it Trader Joe's. And help seaweed any of them. And, lo and behold, their TSHs fall down to the normal range. So I'm seeing just this easy to fix fundamental problem that the government recognized 100 years ago. And we've forgotten it. And so let me say, so the average person is sitting here listening to you and me going, holy cow, that's a lot to look at. And my doctor, he doesn't even, what's a fasting insulin? And in fact, I will tell you that I've yet to see a fasting insulin on any blood test that's brought to me from any practicing physician from around this country. And personally, I'd much rather see a fasting insulin level than a fasting glucose or even a hemoglobin A1C. But how does the average person who picks up your book put this into effect? How do they get these tests? Is there a system? Can you make your doctor do this? Where do you go? This is such a great point because we are all in the early days of a true revolution. And my argument is this is the bloodiest revolution ever because so many people are going downhill without realizing that there's a lot that can be done. So this is a revolution. We are changing from 20th century medicine that asked what is the diagnosis but didn't look for the root cause to 21st century medicine that asks why and looks at the root causes and identifies and treats the root causes. So the first thing to do, very simple, grab a few of these books, the one that you wrote very helpful. I've enjoyed it very much. Looking at all the different pieces that contribute to these problems of chronic illness. And thank you very much. And grab the end of Alzheimer's. We go through every single one of the tests that you need to get. And yes, your doctor can order it. But you're absolutely right. Many doctors will not order it. So then what you can do is we are we've trained now 450 practitioners from seven different countries and all over the United States to do our protocol to order the right tests to get the right computer based algorithm that we use and then to generate the correct and optimal program. This is no longer about monotherapeutics. This is about programatics. And so we'll have a thousand trained by the end of this year. Our functional medicine is working with us. We have our next training in Dallas actually in September and then another one in Miami in December. We had an earlier one in Los Angeles back in April. So we will continue to have these different times where we train people. And my hope is people will begin to slowly see that in fact these are the critical things for your health. And in fact, Alzheimer's should be a rare disease. If we all get these parameters evaluated when we're relatively young or if we start to have symptoms as early as possible. Now fortunately lately we've seen people even late in the course with some response but the earlier the better no surprise. And so I think when this becomes standard of care and people realize yes you need to look at these and you're you know of course the insurance companies have to ultimately step up and say you know what we can save. There is a as you know over 220 billion dollar price tag per year on Alzheimer's disease in the United States. It is shocking. It is going to bankrupt Medicare if we don't do something about it. In fact we can all do something to reduce that bill by getting a Cognoscopy and by getting on the appropriate prevention or early reversal. You know and I bet a Cognoscopy is a lot easier than a Cognoscopy. Much easier. Probably far more pleasant. Much more pleasant. Nobody sticks anything in your head. It's a little bit of a few blood tests and an online cognitive assessment. Easy to do and really it really can save you time in a nursing home. And your book will show people well I know it does but your book shows people how to do this. Exactly. It goes through and it goes through each test and says you know why would you want to know your fasting insulin? Why would you want to know your copper-zinc ratio? And so hopefully you know it was written actually both for doctors and for patients so that anyone, caretakers, et cetera, health coaches, et cetera, anyone can pick this up, look through this and look at you know why do you get this test? Why is this so critical? Well you know you're someone who's really spent your life in this and all of this what you're recommending is certainly not your first rodeo as I like to say. So what are you working on now? Now that you've figured out how to end Alzheimer's where to next? So what we're doing, first we're doing two things. Number one is that we are looking at how can we make this effective later and later and later? So even if someone is at end stage can we really bring them back? And then if they plateau partway back can we now add things to bring them all the way back? So that's the question. We know that we, basically anyone who's early stage has done very well but the people later stages it's more difficult and we want to know what do we need to add? Do we need to add specific neural stem cells? Do we need to add specific intranasal trophic support? What are the things that do we need to add antibodies to remove the amyloid once we've gotten rid of the cause of the amyloid? So lots of questions about that and of course as you can imagine we're also looking at what if we do the same sort of thing but directed again at the biochemistry of ALS, Lou Gehrig's disease or Parkinson's or Lewy body? So we're just beginning to see if this sort of approach can be applied of course with the appropriately modification or again for Occam's network of those diseases can we now improve ALS? Because as you know neurodegenerative disease has been the area of greatest biomedical failure. We have not previously had anything to do about these problems. So that's where we're going in fact we're writing up a paper right now on the next 50 people who've responded objectively and very well to the protocol and another one on the type 3's what's the best because there's virtually nothing in the literature about how do you manage type 3 optimally and how do you prevent it? This is the toxic form. So you know in that light let's suppose you or a loved one or a family member has been given a prescription for Aricep or an Exelon patch and say this is the best treatment there is you've got it. Good luck. What do you do? Again there's nothing wrong with the drug it patches one hole beautifully. There's of course the one concern that has been pointed out over the years for Aricept where you have to be careful Aricept inhibits your colonesterase so therefore you have more acetylcholine at your synapses but the problem is your body responds by making more colonesterase so if you suddenly cold turkey the Aricept you can actually decline quite significantly so you simply don't want to cold turkey it and we recommend for people who come in on it stay on it fine we will add all the other things which should actually help it to work even better. So what I would recommend is no problem if you want to work with your doctor and be on a medication but it's good also to seek the counsel of someone who knows about a protocol that is a functional medicine associated protocol that will then look at the actual drivers when you're giving a drug you're saying I'm not bothering to look at what's actually driving the process I'm just because I only have a few minutes I'm going to cover it quickly with this and then sorry you're not going to do very well well if you bother to look further you're going to find for each person what is driving the process. On that same line I've heard you talk what do you think about statin drugs in the brain any opinion? You know this is the statin drugs again probably the areas of greatest controversy right now are bio identical hormone replacement and statins people tried for years to look to see whether statins could actually be a treatment for Alzheimer's it never showed to be a treatment my belief from all the data we have so far is that the problem is you're seeing both a positive and a negative effect so for some people the net will be slightly positive and for some people the net will be slightly negative no question some people go on statins and immediately lose their memory that's well described it's in the brochure etc it's a well known side effect but for many people they don't have that problem and so on the one hand you will get an improvement for example because of less inflammation however my argument is there are lots of better ways to decrease your inflammation so you don't need to use that because there are the negative effects and in fact years ago when we started looking at this balance this synaptoclastic-synaptoblastic balance we thought look let's screen all the drugs in the pharmacopeia because of course Bruce Ames years ago developed the Ames test and told us about carcinogens how we could screen for carcinogens but nobody ever tells you about dementogens and we realized yes there are lots of dementogens out there when we screened through all the drugs guess what came up first as putting you on the wrong side and that was specific statins and interestingly the one that was the worst was the one that had already been taken off the market for the Sariva statin which has some bad side effects statins do have this potentially negative effect but they also and there are publications showing they have potentially positive effects so my argument is if you can control your lipids with other ways go there first if you can't control it any other way and it's not going to damage your cognition acutely then you might play with fire and use these but if you can do it another way like with exercise with all the other things that we now know are available then in fact that's probably for your brain the better way to go okay yeah statins I think actually prevent lessen heart disease by actually reducing inflammation they actually hit the mute switch on toll-like receptors but I use them as a band-aid or a cast on someone until I get those factors causing their inflammation affected and gone and then I try quite frankly to get people off of statin drugs we usually find they don't need them once we fix the underlying cause yeah again they're trying to subvert physiology yeah absolutely so any last words of advice obviously first last word the book it goes on sale in a couple of days August 22nd you can obviously pre-order it on Amazon or Barnes & Noble or go to your local bookstore please and pre-order it this is you know I've my quotes on the back this is quite frankly a life-changing book this is something that really all of us need to be aware of no matter what our age no matter what our health because as you said and I said this is an epidemic that unless we do something it's going to break Medicare it's going to break all the insurance companies and you and I both believe that all of us have the power with the information that you're providing in this book to take control of this and to actually reverse this you know once again folks Dr. Bredesen has devoted his life's work to understanding all this and he has taught me a huge amount of at the cellular level at the molecular level how this is being is happening and in the book he actually makes it accessible for Joe Blow to understand what they need to do and you know it's brilliant writing Dale and congratulations so any final words just that this is a trillion dollar global problem and of course the number of dollars doesn't begin to describe suffering all the pain that people and families go through it affects the workforce all the caretakers another thing to note is this is a female centric disease 65% of patients and 60% of caregivers are females this is a huge global problem that is growing and in fact we absolutely can do something about it literally no one should get Alzheimer's if you do the right prevention and the right early reversal we can all take a huge bite out of this there are 45 million Americans who are currently living who will develop Alzheimer's and in fact we can reduce that dramatically if we all get the appropriate tests and get on the appropriate prevention or early reversal alright well I'm gonna I'm gonna let you go the book the end of Alzheimer's by Dr. Dale Bredesen my colleague and friend and Dale it's always good to see you and I'm sure we'll see each other again very shortly I look forward to it alright thank you Stephen alright thanks a lot take care


Aaron Boone, the first question from Meredith Morakovic. The manager's report is brought to you by Geico. Aaron, do you feel like that was a wasted start from Jay Hap? Well, I mean, we didn't win. So that's the frustrating part. But it doesn't take away the fact of how well he pitched. And being able to give us some length when we really needed it. But to really give us a really good chance to win and we had a lot of opportunities tonight. I actually thought different from Baltimore, where we were getting held down. Tonight we saw a lot of good at bats up and down the order. Just weren't able to punch through. And right now, we understand where we're at and close isn't good enough right now. We need to find a way to get it done. I thought DJ had some really good at bats and big spots. Wynn kind of knocked his ball down and right. And a great play up the middle with some runners out there. So we did a lot of good things tonight. But right now, close isn't good enough. We got to be able to find a way to punch through. And we got to start that tomorrow. Mention punching through 0-7 with runners in scoring position. 10 men left on base. You said the at bat qualities were a little better. What told you that despite the results? Yeah, I mean, just up and down, I thought we got some really good counts. Obviously, we created a lot of traffic, made it real hard on Walker. LeMaheuse two at bats with runners in scoring position. The ball to right, that's probably a homer most nights. And the ball that Espinall made the great play up the middle. But we got to find a way right now. And we start tomorrow. We can take a next question. Eric Bowlin, please unmute. Aaron, we've all heard the Bill Parcells quote. You are what your record says you are. Do you feel like a 500 team? I know we're better than that, but we have not played to our capabilities. And obviously, the last couple of weeks has been a rough stretch to get us to that point. So we still have time here to turn this thing around and confident we will. But I mean, we are, we're 500 right now. So that's the reality of the situation. But the other reality is it's there for the taking for us. We don't need anyone's help right now. We need to play well. And if we do that, the season will take care of itself. Thank you, Aaron. Yep. Next one to George King. Aaron, what did you think of Gary? I thought he had good at bats, hit the ball hard to third his last time up, smoked the ball to left. I thought he did a better job of laying off some secondary stuff. He expanded on this one strikeout. But I thought he got off a lot. I thought he had good at bats and got off some good swings tonight. Just didn't get any results for it. But I thought he looked pretty good.


jobs with the fastest pay growth. That's what we're going to be talking about today, but before we get into that, gently tap the like button in order to defeat the evil YouTube algorithm as always. On this channel, we talk about personal finance, college degrees, careers, and opportunities that are going to lead you to success. We also talk about avoiding some of the common financial traps that are so easy to fall into. And if that sounds like something that you're interested in and you haven't done it already, go ahead, hit the subscribe button, ring the notification bell so that you never miss a video. Now with that out of the way, let's jump right into it. We are going to talk about number 10 on the list, which is going to be user experience designer. This is also known as UX UI designer, user experience, user interface designer. There's a lot of different names for it. But basically this is all about designing websites and applications and things like that that are extremely user friendly. We're talking about the usability, the usefulness, desirability, how easy it is, how ergonomic it is. Frictionless. And of course, when all of those things are better, the product is much more likely to be purchased. So the median based salary in November of 2015 was about $70,000 a year. In 2018, it was about $75,000 a year. And in 2019, it's over $77,000 a year. So the wage growth from 2018 to 2019 was about 2.75%. And the wage growth from 2015 to 2019 was about 9%. That is really, really good. Most professions are not going to be gaining nine, almost 10% wage growth over a four year period. Now this is one that only requires an associates degree generally speaking to get into it. Some people can even break into it without an associates degree. Now the cool thing about this one is it is technical. It has that technical side of things, but it also is very artistic. Now I've talked about this a lot on the channel, but artistic type professions are very popular, just about everybody wants to go into them. And so unfortunately, they usually get saturated relatively quickly. However, UX UI designers have a ton of different skills. And it's not just the art part. They also have those technical skills as well. We're talking about branding, typography, icons, extensive skill with design and prototyping tools, and all other types of design skills. And when you put it all together, it's like, whoa, that's impressive, that's a lot. You're also going to have a very good mix of kind of introverted creative type work where you're just basically by yourself and you're designing. And then if you're an extrovert, you're also going to have that side of communicating with other departments within the company. So you're probably going to be talking with marketing a lot, for instance. So for those of my audience who are artistic, but they also just want to have a normal job, they don't want to be kind of like an entrepreneur, which a lot of artists have to be. This is a really good option. Number nine on the list is going to be a buyer. So the shopaholics in my audience are going to love this one because you're basically going to be shopping except you're spending other people's money. And so you're going to be representing businesses and making sure that they have enough of whatever materials they have to have. So for instance, let's say you're working for a construction company, you got to make sure that they have enough cement, they've got enough metal, they've got enough iron, enough steel. And then, of course, you're also going to be negotiating prices because the prices for those are going to fluctuate a lot throughout the year. So the median based salary November of 2015 was about $54,000. In November of 2018, it's about $58,000. And November 2019, $59,000, almost $60,000. And then the four year wage growth from 2015 to 2019 is going to be 9.1%. So personality wise, this is going to be one that's going to be better for people who are a little bit more outgoing and social. The reason for this is because you're going to be forming relationships with different vendors and sellers. And let's say, you know, all of a sudden, nobody can get a hold of any concrete, you're going to want to have a relationship with somebody. So they put you at the top of their list. This is what's going to make you extremely valuable to your company. And getting supplies can range anywhere from just getting basic office supplies for an office, all the way to ordering a bunch of, you know, concrete or rebar or anything like that for a construction company. So you're basically responsible for making sure that the company has enough of whatever supplies that they need. And if they ever need any extra supplies, you're the person that they go to next one on the list is going to be an information technology manager. So basically all of the information technology within an organization is going to be managed based on the needs of each individual organization. Hello, IT. Have you tried turning it off and on again? That's what IT management is all about. So in 2015, the median salary was going to be about 79,000. In 2018, it's 83,000. And in 2019, it's 86,000. So the one year growth was about 3.18%. And the four year wage growth was 8.16. So this one has been growing really steadily over the last five years. And last year grew quite a bit. Now, this is one of those fields where technology is evolving so quickly, it's evolving every single day.  Technology is also one of those careers. And I've said this so many other times, where you can get a job pretty much anywhere in the world. There's a lot of careers out there where sure, you can get a job, but you're going to have to move somewhere and it might not be a place that's desirable. With a lot of the different technology careers, you can literally move anywhere you want, some of them you can even be remote. There's a lot more to this career than asking people whether they tried turning it on and off again, you'll have to constantly be learning, getting new certifications, but you're also going to get rewarded really well for that. This is a great career if you're somebody who likes problem solving and being really helpful. Number seven on the list is going to be data analyst. Now, you're probably noticing a turn here. There's a lot of technology related careers. And basically what you're going to be doing here is you're going to be studying, modeling, inspecting all different types of data. And the goal of doing this is to organize and understand the data in such a way where you can make real life decisions. Now, in 2015, they were making around $57,000 a year. In 2018, it's $61,000. And in 2019, it's about $63,000. That means it's grown about 2.7% in the last year. And over the last four years, it's grown 10%. Now, this one will be a really good combination of hard analytical skills as well as communication skills. You're going to have to be able to understand and analyze the data on a pretty high level. But at the same time, you're also going to be able to communicate that data in layman's terms to business people who aren't as technical. You're going to be talking to managers and executives and telling them what your conclusions are based off of the data and why that is. Then you can suggest changes that you can make in order to make things more efficient. So there's some other careers that I've talked about before, like data scientists, for instance, that's definitely more on the analytical and technical side of things. Whereas data analysts basically just understand the data so that they can communicate that data to managers and executives. So it's a little bit less technical and a little bit more communication. Number six on the list is going to be a design engineer. All right, so design engineering is basically exactly what it sounds like. So as a design engineer, you're going to be focused on the engineering side of things, so the practical side of things. But it also does have a little bit of an artistic side as well. So in 2015, they were making around $69,000 a year. In 2018, they're making $71,000. And in 2019, they're making $74,000. This is a one-year wage growth of about 3.6% and a four-year wage growth of 8%. Now, there's a lot of mechanical engineers, for instance, that go into design engineering. There is some art to this, but unfortunately, when I was looking it up, it's not as much as you might think. You will be working with computer aided design, also known as CAD, but it's mostly about making things work. You're going to be paying a lot of attention to schedule, cost, efficiency, and manufacturability. You have to balance all of these different things and make a final product that makes everybody within the company happy. Number five on the list is going to be a sales manager. So basically, you are going to be a manager of your own sales team, and you're going to coach and prepare that team to make as many sales as possible within a company. In 2015, they were making around $58,000 a year. In 2018, they're making $63,000. And in 2019, they're making $65,000 on average. That means the one-year wage growth is about 2.8% and the four-year wage growth is 11.9%, almost 12%. So one unique thing about this role is you're going to be in the field seeing customers because you're going to be watching your sales team interact with customers. You're either going to be directly there out in the field or you're going to be listening to them talking on the phone. But at the same time, you're also going to be interacting with people within the organization. So that gives you a unique perspective. A lot of the time, people within the organization don't actually interact with customers. And so that gives you a really good perspective and a unique chance to teach them. Now, of course, you'll be keeping track of what's known as KPI or Key Performance Indicators. You'll be motivating your sales people, figuring out how to get the best performance out of them.  This is another really good one and it's growing extremely fast. Number four on the list is going to be a surprise and it's going to be a truck driver. I don't think I need to explain what this one is. In 2015, they're making $49,000 a year. In 2018, they're making $55,000 and in 2019, they're making $56,500. That's a one-year wage growth of 2.6% and a four-year wage growth of 13.4%. Now, the cool thing about this one is you don't need any schooling whatsoever to get into it. You can literally graduate from high school and within a month, you can be a professional truck driver. Now, the money is going to vary quite a bit here. It really depends on what specialty that you go into. There's plenty of truck drivers out there that are making six figures a year. You can make even more than that if you own your own truck, if you get a little bit entrepreneurial. And one really cool thing about this one is you can save up a ton of money, especially if you're young and you don't have a family that depends on you. And the reason for this is because you don't need to own a car or a house and those are usually the two biggest expenses. You can pretty much just live out of the truck and that way you get to save a ton of money on rent as well as car payments. So because of this, a lot of people are able to just bank money as a young person working as a truck driver.  But this is also a great career if you want to travel and see the country. Now, of course, there's going to be a lot of downsides to this, especially if you're a long haul driver where you're going to be away from your family for weeks or even months at a time. But this is a really good one to look into. Number three on the list is going to be a property manager. So basically in layman's terms, let's say there's a landlord who owns like 20 or 30 houses and they've been managing it all by themselves. Eventually they get tired of managing all of those houses and getting those three o'clock calls in the middle of the night to fix their toilet. And so they look into hiring someone to do most of the work themselves. This is where the property manager comes in. There's somebody that you can hire to manage all of your properties. So in 2015, they were making on average $48,000 a year. In 2018, it was $52,000. And in 2019, it's $54,000. This is a one year wage growth of 3.51% and a four year wage growth of 13.3%. This is also another career where you do not have to have a college degree in order to get into it. You can get into property management right out of high school if you want to. It's kind of similar to being a real estate agent. So there's a ton of different things you do here. You would of course advertise to find tenants. You would also kick them out. If you have to, you'd be collecting rent. You'd be keeping up maintenance on the properties as well as maintaining the properties themselves. And you'd be taking care of all the legal aspects of owning and renting a property. It's a lot of work, but that's why they get paid so well. Number two on the list is going to be a claims adjuster. So this is basically the person that you talk to after you've gotten into an accident, for instance. So I'm sure a lot of people who are watching this video have been re-rendered or they've had a minor accident before. So you give your insurance company a call. You tell them what happened. And then a few days later, somebody calls you back and that person is usually the claims adjuster. So in 2015, they were making $48,000 a year. In 2018, they're making $53,000. And in 2019, they're making $55,000 a year. This is a one year wage growth of 3.69% and a four year wage growth of 12.9%. This is another one where you don't have to have a degree in order to get into, although there will be some training. So you're going to spend quite a bit of your day talking to people on the phone about whatever accident happened to their house, whatever insurance claim that they're filing. For instance, you might be talking to people about the details of a car wreck. So a few years ago, I was driving on the Las Vegas Strip and all of a sudden I hear this huge crash right behind me, this huge bang sound. And then about half a second later, as I'm looking back, my car gets hit. So what basically happened here was the person who was parked right behind me at a stoplight got hit so hard that it actually hit that car into my car. So the person who hit them was going way too fast. Now of course the person who hit them tried to claim that the car that was in the middle hit me first, stopped all of a sudden and then they subsequently hit them. So the claims adjuster called me just to clarify details and I told them what really happened. And so the person who was in the very back was 100% responsible for the entire accident and the person in the middle and I had zero responsibility. As a car insurance claims adjuster, for instance, you'd be talking to different mechanics and all kinds of different people who might be working on the car that got into the accident. And in rare cases, you might even go and look at the car in person. Number one on the list is going to be a financial advisor. Now this is a really good one. It's one I've talked about before on this channel. So you're basically going to be talking to everyday people and giving them advice on their personal finance needs. So in a roundabout way, I'm kind of a financial advisor, although I'm not talking one-on-one with people, I'm just giving advice on my YouTube videos. But this is a really good career and I think it's one that's getting more and more popular and you'll be giving people advice on investing, saving, you know, getting real estate as well as planning for retirement. Now in 2015, they were making around $48,000 a year. In 2018, it's $54,000. And in 2019, it's $57,000. So this is a one-year wage growth of 4.8%, which is insane, and a four-year wage growth of about 17.8%. Again, this one makes me really happy because I like seeing normal people get educated about personal finance. I think this is something that should be taught in school. It should be mandatory, but for some reason it isn't. Now I will say that not all financial advisors give the best advice when it comes to investing. I've done extensive research on this and I've seen some here on YouTube that will give you good advice, but not the best advice. So for instance, I always advise investing in what's known as an index fund and you can look that up if you haven't already. I've made many videos about it. However, a lot of personal financial advisors will tell you to invest in a mutual fund, which is similar to an index fund, but it's just not quite as good. The big difference there is a lot of mutual funds will give some type of incentive to people in order to recommend their service. So the personal financial advisor will likely get some kind of payment for you if you decide to sign up. Whereas with index funds, that's really rare just because of the fact that there's such a low cost in order to sign up for an index fund. They don't really make all that much money off of you. So again, this is good advice, but it's not great advice. I'm not saying they're scammers or anything like that. I'm just saying that they're not giving you the best advice because of the fact that they're incentivized to give you the second best advice. Another thing that I've been seeing is them recommending that you sign up for life insurance when the truth is that not everybody needs life insurance. It's something that's good for a very specific type of person. It can be a great investment, but for the most part, there's quite a few people out there that absolutely do not need whole life insurance. They might be better with term insurance, for instance, but whole life insurance, you don't need it most of the time. But again, they're incentivized to get people to sign up for it. So a lot of people end up promoting that. If you haven't done it already, go ahead and smash the like button, hit the subscribe button, ring the notification bell, comment down below any thoughts, comments, criticisms, etc that you have on the video. And before you go, make sure to check out my other videos right here. I made them just for you.


This study aimed to identify attributes and facilitators for a comprehensive vaccine intervention in OBGYN clinical settings by conducting in-depth interviews with 24 providers from urban and suburban practices in Georgia and Colorado about their immunization attitudes, practices, and patient experiences. Six major themes emerged, strong provider buy-in for maternal immunization, the supporting role of clinical, interpersonal cues for vaccine promotion, varying provider patient communication approaches, an urgent need for a designated office immunization champion, reimbursement and practice implementation challenges, and region differences in attitudes toward maternal immunization. The findings reflect needs for immunization champion identification, training, and support, along with best practices guidelines to improve coordination of vaccine promotion and delivery efforts in OBGYN provider offices. Provider training on communication approaches to enhance acceptance and uptake of maternal vaccines is also warranted.


That's my stage name. My ID name is Maureen Katima. Maw unatwambia japa you adjust a woman? I'm just trying to give status in manamke. Kwa sabu manamke a kwa in different forms. We are trying to appreciate a woman, trying to show feminism and prejudice in women. Most of it all women are so loving and lovable. But I thought women are their own worst enemies? No, it depends. Not all women are their own worst enemies. Tell me what it depends on. It depends because when we support each other, then it will be strong. When we support each other, we become strong as women. I like that. I like the video. I like the theme. It's very cultural and looks really nice. I will tell me about the concept. What do you think? I think it's something traditional. It's something traditional. It's something traditional. It's something traditional. This is something kwa afrikan is still very famous and traditional. Maw unatwambia japa uwa kwa kwa kwa kwa kwa kwa kwa kwa kwa is. Niki eveni kwa kwa kwa kwa is, kwa kwa kwa kwa kwa is. It depends upon the experiences we experience. What do you think A sofa, Ala I don't clean? Because of it We are two very close people So you must make a decision If you don't know how good g this people are Would you look at her different Not sure if you looked at her but Everything was just beginning but we got a problem hendam sigu na kupReally yo u usikini Siu isa zatu hadi Omoo periki Nana kwa wajera kupiyo nii.  Ay! Nili toca? Can we just have a moment for all the surets who do amazing things about? So where we come, am Sanimo What are you bringing to the table? Fasutu. Bo agu lii poi ii o koshun mania Corona No, actually this is my very first song Register My very first one, yes I just released it last week on Tuesday So I wasn't actually going into music but whatever I'm planning I need to sing or I need to do something because I had something in mind First of all I do have a YouTube channel I started on it but it's called Yangadans It's a channel that I'd love for the youth to come together and talk about themselves, express their feelings So I thought, apart from the Yangadans channel I needed to create something more I needed to create something like more katima, muziki With that I needed for us to connect as youth through music but not particularly for dancing, clubbing and all that We can use that moment for education educating one another, maybe doing some business 1, 2, 3, something that will add something into our pockets or maybe into our future So in order to have that in going I also needed to have my own music so that I could start on it So this is just about a stepping stone to what is coming I want to come back, I want to scare something in pocket You know what to do Even though I'm a Zoom kid kid Ok, so I don't even know how to properly ask you because right now in Noliza there's a lot going on in Africa Sana Sana Iso Saita West, South Street and South there's a branch of police that is being brutal to the people it's supposed to be protecting Kongo, the things happening in Kame Run and we're trying to figure out kama ma celeb, wakismama ma se mekilam to a protest and we protest peacefully, please they decided that so sa wewa suma jo mejie kapo like you put yourself in the limelight so you're more or less a celebrity you have people who follow you you have a follower no matter how big or small I laughed inna when you dame you ektu ningumu kwa celeb ala fetepe kwa dame because you might have opportunities and you might say I like you too so you know what I'm talking about how would you deal with that as a celebrity who has a voice Ok, I believe those people who believe in you if you stand in front I'm sure they'll be able to follow you at the bank kwa zata given the fact that you're a lady kuna ma dame hadko they can stand and they say something and then it's being done kuna vilipi inafiwa nga moment you have to wumiliakidoko maybe tani kwa stivi but we have to do this thing it has to happen so I think they have a voice na fikimali wa kuleze ma roja za ma roja ulewa as if we're going to raise the family together do you have that to ma backlash where kwa dame na jari buktu sku ma kwa youth and trying to but there's someone using your femininity against you but I think the key thing is believing in yourself because people will judge you for whatever you're doing but that will that you have I want to do this thing then you go ahead and do it no matter what happens you have to be strong I like your vibe so to kimalizia you're going to give us socials but before that so where's your destination my destination is I'd love to create a foundation for the youth whereby we are able to stand up for ourselves not just by word maybe by career, family, religion and all that stuff as in we need people who are for example I've had this thing alcoholism for example people get into something maybe they do not know maybe because of influence and stuff but if we do have a foundation whereby we get to educate each other, we get to do stuff together maybe in one of the other and then I believe when you are a youth and you are a youth as well kun aviationna bond kun avleniki kwanbi akitu Not living alone with your parent kun nemi iki kwanbi akitu, kun avleni uineza ni understand that uineza kwa in the same page so that's what I want to create ...and grow as youth Kuna kakitu Knit Fokus Kuna kakitu, kakitu, kakitu Kakirumu wei mumane So where do we find you on social media?  Okay my last words especially to the youth I'd like to say I believe in yourself And whenever you need something done, go for it. It will happen.  So you changed yours? No. It's a kukoshani also, buddy. Let me believe so then. Let me believe in you. Thank you.


One historian described the beginnings of Jefferson Street as a simple wagon trail that traveled from the west side of town to the river. But as the nation entered into the Civil War and emerged on the other side of it, it became something different, something much greater. To be what's been up and coming, home to amazing teachers, historians, and artists, you name it. It's all here. A legacy, a real representation of a divine excellence where the soul is alive and the culture is food. These are our roots. Forever a center activity for the community. Simply said, the core, the heart, the essence. Well, Jefferson Street was, at one time, the black mecca of Nashville. We were definitely community-based. Everything was centered around the community. We had everything that we needed. We could live our whole lives right here on Jefferson Street. And some people did. We've been in business since 1966. And it started by my father, which was Earl Price Senior. We're here to stay in the community. And when a lot of people don't realize this, we've been here for over 56 years in a business. So we've been through the ups and downs and the highs and lows. Our cable line and several other names are original names for Africa. We wanted to focus on things that were from our history. So my father was opened up the shop to focus on creating positive images and highlighting the rich history of people from the African diaspora. I wanted to be able to provide an environment where it wasn't just a place they came in at their hair done, but it was a place they was able to talk about whatever they that was on their mind.  And we have fun at the same time. But then sometimes it's just moments where they just need to relax. And I knew that's the kind of environment I wanted to set for them. We chose Jefferson Street because it is a historically African-American neighborhood. It's the mecca of African-Americans in Nashville. So it was very, very important for us to put this cocktail concept on Jefferson Street due to the history of Jefferson Street and what it meant or what it still means. Woodworking was my hobby. I actually majored in industrial arts and technology at Tennessee State University. And woodworking was my specialty. And so as a hobby, I began to make frames for friends and family out of my home. I never dreamed that I would have a business on Jefferson Street when I was coming up, but it just happened that way. Love being a part of Jefferson Street. I love interacting with the customers. And we've seen other businesses grow along with us. Where else would you be besides Jefferson Street? Besides here, where are you going to get the love? The family. This is family right here. They take care of me. I take care of them. Well, I really never thought about a newspaper or a magazine. Like they were reinforcing things that happened that was bad in our community. And then I told my husband one time, there are good people in this town that are educated. We have FISTSU, American Baptist College, and Meharry Medical College. Why can't we let these folks know that we have educators in this town? We were always north of people of faith, working to keep our hearts strong and our strength great. Important to the world, preservation of wisdom, a reflection of what music is, what miracles are, what it means to grow. Historical, authentic, prepared for the main event, a major attraction. You're seeing it, the pride of this place, essential to the progression of what's coming. A value that's valid, that's powerful, that's dominant, that's celebrated, that's noteworthy. Most importantly, we're respected. Products of a magical atmosphere of quality and spirit. What can I say? We're always new.